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Liliana Bernardino currently holds the position of Associate Professor with Habilitation at the Faculty of Health Sciences and Principal Investigator at the Health Sciences Research Center (CICS-UBI) of the University of Beira Interior (UBI). She holds a Ph.D. in Molecular Biology from the University of Coimbra in 2008, conducting research at the Mario Negri Institute for Pharmacological Research (Milan, Annamaria Vezzani¿s lab), and at the University of Southern Denmark, Odense (Denmark; Jens Zimmer¿s lab). Her doctoral studies contributed to revealing the dual role of inflammatory molecules on neuronal survival and repair (Bernardino et al., 2005, J Neurosci; Bernardino et al., 2008, J Neurochem, Stem Cells). She pursued postdoctoral training at the Center for Neuroscience and Cell Biology (CNC), and the University of Beira Interior (UBI) from 2008 to 2012. During her postdoctoral studies, she unveiled cellular and molecular processes triggering neurogenesis (Bernardino et al., 2012, Stem Cells; Santos et al., 2012, ACS Nano). This significant contribution to the field earned her prestigious recognitions, including the Calouste Gulbenkian Foundation Research Prize and the L'Oréal Portugal Medals of Honor for Women in Science (2010). From 2010 to 2012, she was appointed as an Auxiliary Professor at the Portuguese Catholic University, teaching several curricular units to the Bachelor in Biomedical Sciences and Master in Dental Medicine. In 2013, she was appointed as Auxiliar Professor at UBI, and from 2023 she is Associate Professor. Her current main scientific interest is the development of novel therapies for Parkinson's disease. She was a pioneer in identifying novel targets (microRNA, retinoic acid, histamine) along with innovative delivery strategies (nanoparticles, small extracellular vesicles) that have therapeutic benefits for Parkinson's disease and stroke (Ferreira et al., 2016, Nanoscale; Saraiva et al., 2016, J Control Rel; Ferreira et al., 2020, Nature Communications; Esteves et al., 2022, Mol Therapy, etc). She is a (co)author of 66 peer-reviewed articles published in international journals, including renowned journals in the field, 1 book, 12 book chapters, and 4 patents. She has a h-index of 33 and more than 3.5K citations (Scopus). She (co)supervised 3 post-docs, 8 Ph.D. candidates (funded by FCT, MIT-Portugal PhD program, EMBO grant), and 19 MSc theses (Biomedical Sciences, Medicine, Biochemistry, Biotechnology). Dr. Bernardino actively participated as a researcher and Principal Investigator in national and international grants (total of 18 grants, >3500K euro). She has played pivotal roles in numerous management activities, including President of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC, elected in October 2023), and appointed as a member of the Faculty Council (2020-present), Pedagogical Committee (2017-2023), and Director of the Bachelor in Biomedical Sciences (2017-2023) at the Faculty of Health Sciences (UBI). She was also a member of the Executive Committee and elected coordinator of the Neurologic and Neurovascular Disorders Group (2015-2017, 2021-2022), a coordinator of the Interaction with the Society committee (2015-2017) at CICS-UBI. She has been an evaluator of several funding agencies, such as EIC Pathfinder Open, FCT-Portugal, Marie-Curie fellowships and doctoral networks, National Science Foundation (NSF), Deutsche Forschungsgemeinschaft (DFG), European Cooperation in Science and Technology (COST actions), etc. She has been a Reviewer, Review Editor, Editor of Special Issue, Associate and Guest Associate Editor of different Journals. She contributed to the organization of national and international scientific events, was an invited speaker at national and international conferences (e.g., Annual Meeting of the European Society for Clinical Investigation 2012 and 2023, among others), and coordinated and organized several outreach activities.
Identificação

Identificação pessoal

Nome completo
LILIANA INÁCIO BERNARDINO

Identificadores de autor

Ciência ID
581D-8F48-53EC

Endereços de correio eletrónico

  • libernardino@fcsaude.ubi.pt (Profissional)

Moradas

  • Av Infante D. Henrique, 6200-506, Covilhã, Covilhã, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Português (Idioma materno)
Italiano Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2021/07/30
Concluído
Biomedicine (Título de Agregado)
Universidade da Beira Interior, Portugal
Approved
2008/03 - 2012/12
Concluído
Postdoc fellow at the Center for Neuroscience and Cell Biology, University of Coimbra and University of Beira Interior. Project title: “Histamine versus antihistamines: New modulators of neurogenesis?” SFRH/BPD/34841/2007 (Pós-doutoramento)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2003/10 - 2008/02
Concluído
Molecular Biology (Doutoramento)
Universidade de Coimbra, Portugal
"Inflammation in Excitotoxic neuronal death and Survival: Involvement of Tumor Necrosis Factor-alpha and Interleukin-1 beta." (TESE/DISSERTAÇÃO)
Approved with distinction and honors
2007/06/08
Concluído
III Course on Laboratory Animal Science (FELASA - LEVEL C - Animal Experiment Leader) (Diploma de especialização)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
1998/09 - 2003/07
Concluído
Biology (Licenciatura)
Universidade de Coimbra, Portugal
17/20
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2013/01/01 - Atual Investigador principal (carreira) (Investigação) Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2023/08/14 - 2023/08/20 Investigador visitante (Investigação) Universitetet i Bergen, Noruega
2020/03/01 - 2020/03/31 Investigador visitante (Investigação) Weizmann Institute of Science, Israel
Weizmann Institute of Science, Israel
2015/10/15 - 2015/11/10 Investigador visitante (Investigação) Università Vita Salute San Raffaele, Itália
2008 - 2012 Pós-doutorado (Investigação) Universidade de Coimbra, Portugal
Universidade de Coimbra, Portugal
2004/03/20 - 2005/03/08 Investigador visitante (Investigação) Istituto di Ricerche Farmacologiche Mario Negri, Itália
Istituto di Ricerche Farmacologiche Mario Negri, Itália
2003 - 2004 Investigador visitante (Investigação) Syddansk Universitet, Dinamarca

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2023/08/01 - Atual Professor Associado (Docente Universitário) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013/01/02 - 2023/07/31 Professor Auxiliar (Docente Universitário) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
Universidade da Beira Interior, Portugal
2010/10 - 2012/02 Professor Auxiliar Convidado (Docente Universitário) Universidade Católica Portuguesa, Portugal
Universidade Católica Portuguesa, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2024/01/02 - Atual Presidente Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
2020/06/28 - Atual Member of the Faculty Council Universidade da Beira Interior, Portugal
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2021 - 2023/10/31 Director of the Bachelor (BSc) in Biomedical Sciences Universidade da Beira Interior, Portugal
Universidade da Beira Interior, Portugal
2021 - 2023/10/31 Coordinator of the Scientific Committee and of the Pedagogical Committee of the Bachelor (BSc) in Biomedical Sciences Universidade da Beira Interior, Portugal
Universidade da Beira Interior, Portugal
2017/08/01 - 2023/10/31 Member of the Pedagogical Coordination Committee at the Faculty of Health Sciences Universidade da Beira Interior, Portugal
Universidade da Beira Interior, Portugal
2021/11/29 - 2022/10/01 Coordinator of the Neuroprotection and Neurodegeneration research group at the Health Science Research Center (CICS-UBI) Universidade da Beira Interior, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2021/11/29 - 2022/10/01 Member of the Executive Commission, Health Science Research Center (CICS-UBI) Universidade da Beira Interior, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2019/10 - 2021/10 Member of the Governing board (Vogal) of the Portuguese Society of Stem Cells and Cell Therapies (SPCE-TC) Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
2017/08/01 - 2020 Director of the Bachelor (BSc) in Biomedical Sciences Universidade da Beira Interior, Portugal
Universidade da Beira Interior, Portugal
2017/08/01 - 2020 Coordinator of the Scientific Committee and of the Pedagogical Committee of the Bachelor (BSc) in Biomedical Sciences Universidade da Beira Interior, Portugal
Universidade da Beira Interior, Portugal
2014 - 2020 Co-coordinator for the management of the Microscopy facilities at the Health Sciences Research Centre (CICS-UBI). Universidade da Beira Interior, Portugal
Universidade da Beira Interior, Portugal
2015/10 - 2017/10 Member of the Audit Board (Vogal) of the Portuguese Society of Stem Cells and Cell Therapies (SPCE-TC). Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
2015/02 - 2017/03 Coordinator of the Neuroprotection and Neurodegeneration research line at the Health Science Research Center (CICS-UBI) Universidade da Beira Interior, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2015/02 - 2017/03 Coordinator of the Outreach Activities section at the Health Science Research Center (CICS-UBI) Universidade da Beira Interior, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2015/02 - 2017/03 Secretary of the Executive Commission of the Health Science Research Center (CICS-UBI) Universidade da Beira Interior, Portugal
Universidade da Beira Interior, Portugal
2013/06 - 2015/10 Member of the Governing board (Vogal) of the Portuguese Society of Stem Cells and Cell Therapies (SPCE-TC). Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2020/03/01 - 2020/03/31 Sabatical Fellowship at the Weizmann Institute of Science, Israel. Fellowship from the Fondation for Science and Technology (FCT, Reference: SFRH/BSAB/150444/2019) Weizmann Institute of Science, Israel
Weizmann Institute of Science, Israel
2015/10/15 - 2015/11/10 Short Term Scientific Mission (STSM) funded by COST BM1402 Development of a European network for preclinical testing of interventions in mouse models of age and age-related diseases (MouseAGE) Università Vita Salute San Raffaele, Itália
Università Vita Salute San Raffaele, Itália
2008/03/01 - 2012/12/31 PostDoc Fellow at the Center for Neuroscience and Cell Biology. Fellowship from the Foundation for Science and Technoloy (FCT, Reference: SFRH/BPD/34841/2007) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2007/12 - 2008/02 Research fellow at the Center for Neuroscience and Cell Biology, University of Coimbra. Reference: PTDC/SAU-NEU/68465/2006 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2003/10 - 2008/02 PhD fellow at the Center for Neuroscience and Cell Biology. Fellowship from the Foundation for Science and Technology. (FCT, Reference: SFRH/BD/12731/2003) Universidade de Coimbra, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2004/05 - 2005/03 PhD fellow at the Institute for Pharmacological Research Mario Negri, Department of Neuroscience, Milan, Italy, under the supervision of Annamaria Vezzani. Istituto Di Ricerche Farmacologiche Mario Negri, Itália
2003/09 - 2004/04 PhD fellow at the Department of Anatomy and Neurobiology, University of Southern Denmark, Odense, Denmark, under the supervision of Jens Zimmer Syddansk Universitet, Dinamarca
Projetos

Bolsa

Designação Financiadores
2022/12/01 - Atual New role for histamine: protecting the depressed brain
2022.13027.BD
Orientador
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2020/02/01 - Atual The interplay between microRNAs and alpha-synuclein: exploring novel therapeutic approaches for Parkinson's disease
SFRH/BD/149036/2019
Orientador
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2024/04/15 - 2024/07/16 Intranasal delivery of Bromocriptine-loaded Ceria Nanoparticles: A potential new therapeutic approach for Parkinson's disease
EMBO Scientific Exchange Grant, European Molecular Biology Organization (EMBO)
Orientador
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Em curso
2017/04/01 - 2023/07/30 MicroRNAs-enriched exosomes as a new therapy for brain repair in Parkinson's disease
SFRH/BD/121822/2016
Orientador
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2020/03/01 - 2020/03/31 Unveiling the myeloid cell-specific role of LRRK2 in multiple sclerosis
SFRH/BSAB/150444/2019
Bolseiro de Cientista Convidado
Weizmann Institute of Science, Israel
Fundação para a Ciência e a Tecnologia
Concluído
2018/10/01 - 2019/05/31 Interdisciplinary Challenges On Neurodegeneration
01-0145-FEDER-000013
Orientador
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Comissão de Coordenação e Desenvolvimento Regional do Centro
Concluído
2017/09/01 - 2018/08/31 Interdisciplinary Challenges On Neurodegeneration
CENTRO-01-0145-FEDER-000013.
Orientador
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Comissão de Coordenação e Desenvolvimento Regional do Centro
2012/09/01 - 2017/12/30 MicroRNA-124-loaded nanoparticles as a new promising therapeutic tool for neural stem cell-based brain repair strategies
SFRH/BD/90365/2012
Orientador
Universidade Nova de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2014/04/01 - 2016/12/31 Therapeutic application of retinoic acid-loaded nanoparticles for neurological and vascular repair in stroke
SFRH/BPD/94228/2013
Orientador
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2012/01/01 - 2016/03/31 Therapeutic potential of retinoic acid-loaded nanoparticles for brain repair
SFRH/BD/79526/2011
Orientador
Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2015/10/15 - 2015/11/10 Targeting the HMGB1-RAGE axis: a new therapy for brain repair in Parkinson's disease
COST BM1402
Bolseiro de Cientista Convidado
Università Vita Salute San Raffaele, Itália
European Cooperation in Science and Technology
Concluído
2009/09/01 - 2013/12/20 Neurogenesis in the hippocampus: histamine and AMPA receptors facilitate differentiation and synaptic integration of new neurons
SRRH/BD/42848/2008
Orientador
Universidade Nova de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2008/03/01 - 2012/12/31 Histamine versus antihistamines: New modulators of neurogenesis?
SFRH/BPD/34841/2007
Bolseiro de Pós-Doutoramento
Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2003/10/01 - 2008/02/11 Inflammation in neuronal death and survival: Involvement of Tumor Necrosis Factor-alpha and Interleukin-1 beta
SFRH/BD/12731/2003
Bolseiro de Doutoramento
Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2023/04/01 - Atual IMMUPARKNET - The role of IMMUnity in tackling PARKinson's disease through a Translational NETwork
COST ACTION CA21117
Investigador
Em curso
2021/01/01 - 2023/06/30 PDSolve - New therapeutic approach to slowdown the progression of Parkinson's disease
PT2020 - CENTRO-01-0247-FEDER-113213
Investigador
Universidade da Beira Interior, Portugal
Comissão de Coordenação e Desenvolvimento Regional do Centro
Concluído
2020 - 2020 Unveiling the myeloid cell-specific role of LRRK2 in multiple sclerosis
Visiting Faculty Program Award, Weizmann Institute of Science
Investigador responsável
Weizmann Institute of Science, Israel
Weizmann Institute of Science
Concluído
2018 - 2020 NANOSTEM: New nanomaterials for neural stem cells drug delivery
721468
Investigador
European Commission
Concluído
2017 - 2020 Interdisciplinary Challenges On Neurodegeneration - ICON
CENTRO-01-0145-FEDER-000013
Investigador
Comissão de Coordenação e Desenvolvimento Regional do Centro
Concluído
2019/01/01 - 2019/12/31 Health Sciences Research Centre
UID/Multi/00709/2019
Universidade da Beira Interior, Portugal

Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2015 - 2018 StrokeTherapy: Therapeutic platforms for stroke
POCI-01-0247-FEDER-003386
Investigador
Comissão de Coordenação e Desenvolvimento Regional do Centro
Concluído
2014 - 2018 Development of a European network for preclinical testing of interventions in mouse models of age and age-related diseases (MouseAGE)
Cost action BM1402
Investigador
Concluído
2016 - 2016 Research Grant on Cerebrovascular Diseases "Terapia celular para a recuperação vascular e neurológica em acidente vascular cerebral
Portuguese Stroke Society
Investigador
Sociedade Portuguesa do Acidente Vascular Cerebral
Concluído
2014 - 2015 MicroRNA-124 loaded nanoparticles: boosting neurogenesis to treat Parkinson's disease
EXPL/BIM-MED/0822/2013
Investigador responsável
Universidade da Beira Interior, Portugal
Fundação para a Ciência e Tecnologia, FCT
Concluído
2013 - 2014 Modulation of microglial reactivity by GDNF: relevance to dopaminergic protection.
PTDC/NEU-BEN/0156/2012
Investigador
Fundação para a Ciência e Tecnologia, FCT
Concluído
2010 - 2013 Histamine versus antihistamines: new modulators of neurogenesis?
PTDC/SAU-NEU/104415/2008
Investigador responsável
Fundação para a Ciência e Tecnologia, FCT
Concluído
2010 - 2013 Role of intercellular communication between endothelial and stem cells in stemness and neurogenesis: new targets for brain repair therapies
PTDC/SAU-NEU/101783/2008
Investigador
Fundação para a Ciência e Tecnologia, FCT
Concluído
2011/01/01 - 2012/12/31 Strategic Project - LA 1 - 2011-2012
PEst-C/SAU/LA0001/2011
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2011 - 2012 Histamine as a promising therapeutic tool for neural stem cell-based brain repair strategies
L'Oréal Portugal Medals of Honor for Women in Science
Investigador responsável
Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2009 - 2012 Heart regeneration by embryonic vascular cells and a biomimetic scaffold.
PTDC/SAU-BEB/098468/2008
Investigador
Fundação para a Ciência e Tecnologia, FCT
Concluído
2009 - 2011 Histamine in the neural and cancer stem cell niche: a role in glioblastoma ontogeny?
FCG 96542
Investigador responsável
Fundação Calouste Gulbenkian
Concluído
2006 - 2011 Microglial and neuronal changes in the hippocampus induced by methamphetamine: role of pro-inflammatory cytokines and neuropeptide Y.
PTDC/SAU-FCF/67053/2006
Investigador
Fundação para a Ciência e Tecnologia, FCT
Concluído
2006 - 2010 Subventricular zone stem cells as a tool for brain repair in temporal lobe epilepsy.
PTDC/SAU-NEU/68465/2006
Investigador
Fundação para a Ciência e Tecnologia, FCT
Concluído
2005 - 2008 Neo-neurogenesis and Microglia in Temporal Lobe Epilesy: Role of Pro-inflammatory Cytokines and Neuropeptide Y in Neuroprotection of New Neurons
POCTI/SAU-NEU/58492/2004
Investigador
Fundação para a Ciência e Tecnologia, FCT
Concluído
2003 - 2006 Neuroprotective effect of neuropeptide Y in excitotoxicity and in temporal lobe epilepsy
POCTI/NSE/46848/2002
Investigador
Fundação para a Ciência e Tecnologia, FCT
Concluído
Produções

Publicações

Artigo em revista
  1. Esteves, Marta; Cristóvão, Ana Clara; Vale, Ana; Machado-Pereira, Marta; Ferreira, Raquel; Bernardino, Liliana. "MicroRNA-124-3p Modulates Alpha-Synuclein Expression Levels in a Paraquat-Induced in vivo Model for Parkinson’s Disease". Neurochemical Research (2024): http://dx.doi.org/10.1007/s11064-024-04130-y.
    10.1007/s11064-024-04130-y
  2. da Silva, Ana Alexandra Flores; Fiadeiro, Mariana Bernardo; Bernardino, Liliana Inácio; Fonseca, Carla Sofia Pais; Baltazar, Graça Maria Fernandes; Cristóvão, Ana Clara Braz. ""Lipopolysaccharide-induced animal models for neuroinflammation – An overview."". Journal of Neuroimmunology 387 (2024): 578273. http://dx.doi.org/10.1016/j.jneuroim.2023.578273.
    10.1016/j.jneuroim.2023.578273
  3. Saraiva, Cláudia; Lopes-Nunes, Jéssica; Esteves, Marta; Santos, Tiago; Vale, Ana; Cristóvão, Ana Clara; Ferreira, Raquel; Bernardino, Liliana. "CtBP Neuroprotective Role in Toxin-Based Parkinson’s Disease Models: From Expression Pattern to Dopaminergic Survival". Molecular Neurobiology 60 8 (2023): 4246-4260. http://dx.doi.org/10.1007/s12035-023-03331-w.
    10.1007/s12035-023-03331-w
  4. Machado-Pereira, Marta; Grayston, Alba; Garcia-Gabilondo, Miguel; Francisco, Vitor; Cristóvão, Ana; Marto, João; Vieira, Helena; et al. Autor correspondente: Bernardino, Liliana. "Retinoic Acid Loaded Nanoparticles Promote Neurovascular Protection in Stroke". Stroke 54 4 (2023): http://dx.doi.org/10.1161/strokeaha.122.041839.
    10.1161/strokeaha.122.041839
  5. Brito, Vanessa; Marques, Mariana; Esteves, Marta; Serra-Almeida, Catarina; Alves, Gilberto; Almeida, Paulo; Bernardino, Liliana; Silvestre, Samuel. "Synthesis, In Vitro Biological Evaluation of Antiproliferative and Neuroprotective Effects and In Silico Studies of Novel 16E-Arylidene-5a,6a-epoxyepiandrosterone Derivatives". Biomedicines 11 3 (2023): 812. http://dx.doi.org/10.3390/biomedicines11030812.
    10.3390/biomedicines11030812
  6. Rodrigues, Artur Filipe; Rebelo, Catarina; Reis, Tiago; Simões, Susana; Bernardino, Liliana; Peça, João; Ferreira, Lino. "Engineering optical tools for remotely controlled brain stimulation and regeneration". Biomaterials Science 11 9 (2023): 3034-3050. http://dx.doi.org/10.1039/d2bm02059a.
    10.1039/d2bm02059a
  7. Esteves, Marta; Abreu, Ricardo; Fernandes, Hugo; Serra-Almeida, Catarina; Martins, Patrícia A.T.; Barão, Marta; Cristóvão, Ana Clara; et al. Autor correspondente: Bernardino, Liliana. "MicroRNA-124-3p-enriched small extracellular vesicles as a therapeutic approach for Parkinson’s disease". Molecular Therapy 30 10 (2022): 3176-3192. http://dx.doi.org/10.1016/j.ymthe.2022.06.003.
    10.1016/j.ymthe.2022.06.003
  8. Esteves, Eduardo; Mendes, Vera M.; Manadas, Bruno; Lopes, Rafaela; Bernardino, Liliana; Correia, Maria José; Barros, Marlene; Esteves, Ana Cristina; Rosa, Nuno. "COVID-19 Salivary Protein Profile: Unravelling Molecular Aspects of SARS-CoV-2 Infection". Journal of Clinical Medicine 11 19 (2022): 5571. http://dx.doi.org/10.3390/jcm11195571.
    10.3390/jcm11195571
  9. Rebelo, Catarina; Reis, Tiago; Guedes, Joana; Saraiva, Cláudia; Rodrigues, Artur Filipe; Simões, Susana; Bernardino, Liliana; et al. "Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications". Nature Communications 13 1 (2022): http://dx.doi.org/10.1038/s41467-022-31791-6.
    10.1038/s41467-022-31791-6
  10. Esteves, Eduardo; Mendes, Ana Karina; Barros, Marlene; Figueiredo, Cátia; Andrade, Joana; Capelo, Joana; Novais, António; et al. "Population wide testing pooling strategy for SARS-CoV-2 detection using saliva". PLOS ONE 17 1 (2022): e0263033. http://dx.doi.org/10.1371/journal.pone.0263033.
    10.1371/journal.pone.0263033
  11. Machado-Pereira, Marta; Saraiva, Cláudia; Bernardino, Liliana; Cristóvão, Ana C.; Ferreira, Raquel. "Argonaute-2 protects the neurovascular unit from damage caused by systemic inflammation". Journal of Neuroinflammation 19 1 (2022): http://dx.doi.org/10.1186/s12974-021-02324-7.
    10.1186/s12974-021-02324-7
  12. Zare, Iman; Yaraki, Mohammad Tavakkoli; Speranza, Giorgio; Najafabadi, Alireza Hassani; Haghighi, Alireza Shourangiz; Nik, Amirala Bakhshian; Manshian, Bella B.; et al. "Gold nanostructures: synthesis, properties, and neurological applications". Chemical Society Reviews (2022): http://dx.doi.org/10.1039/d1cs01111a.
    10.1039/d1cs01111a
  13. Serra-Almeida, Catarina; Saraiva, Cláudia; Esteves, Marta; Ferreira, Raquel; Santos, Tiago; Cristóvão, Ana Clara; Bernardino, Liliana. "C-Terminal Binding Proteins Promote Neurogenesis and Oligodendrogenesis in the Subventricular Zone". Frontiers in Cell and Developmental Biology 8 (2021): http://dx.doi.org/10.3389/fcell.2020.584220.
    10.3389/fcell.2020.584220
  14. Bernardino, Liliana; Volonté, Cinzia; Passani, Maria Beatrice; Ferreira, Raquel. "Editorial: Dual Role of Microglia in Health and Disease: Pushing the Balance Towards Repair". Frontiers in Cellular Neuroscience 14 (2020): http://dx.doi.org/10.3389/fncel.2020.00259.
    10.3389/fncel.2020.00259
  15. Ferreira, Raquel; Napoli, Joseph; Enver, Tariq; Bernardino, Liliana; Ferreira, Lino. "Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine". Nature Communications 11 1 (2020): http://dx.doi.org/10.1038/s41467-020-18042-2.
    10.1038/s41467-020-18042-2
  16. Esteves, M.; Serra-Almeida, C.; Saraiva, C.; Bernardino, L.. "New insights into the regulatory roles of microRNAs in adult neurogenesis". Current Opinion in Pharmacology 50 (2020): 38-45. http://www.scopus.com/inward/record.url?eid=2-s2.0-85076726651&partnerID=MN8TOARS.
    10.1016/j.coph.2019.11.003
  17. Cristóvão, A.C.; Campos, F.L.; Je, G.; Esteves, M.; Guhathakurta, S.; Yang, L.; Beal, M.F.; et al. "Characterization of a Parkinson’s disease rat model using an upgraded paraquat exposure paradigm". European Journal of Neuroscience (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85078945954&partnerID=MN8TOARS.
    10.1111/ejn.14683
  18. Saraiva, C.; Barata-Antunes, S.; Santos, T.; Ferreiro, E.; Cristóvão, A.C.; Serra-Almeida, C.; Ferreira, R.; Bernardino, L.. "Histamine modulates hippocampal inflammation and neurogenesis in adult mice". Scientific Reports 9 1 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85067204850&partnerID=MN8TOARS.
    10.1038/s41598-019-44816-w
  19. Catarina Praça; Akhilesh Rai; Tiago Santos; Ana C. Cristovão; Sonia L. Pinho; Romeo Cecchelli; Marie-Pierre Dehouck; Liliana Bernardino; Lino S. Ferreira. "A nanoformulation for the preferential accumulation in adult neurogenic niches". Journal of Controlled Release 284 (2018): 57-72. https://doi.org/10.1016/j.jconrel.2018.06.013.
    10.1016/j.jconrel.2018.06.013
  20. Machado-Pereira, M.; Santos, T.; Ferreira, L.; Bernardino, L.; Ferreira, R.. "Intravenous administration of retinoic acid-loaded polymeric nanoparticles prevents ischemic injury in the immature brain". Neuroscience Letters 673 (2018): 116-121. http://www.scopus.com/inward/record.url?eid=2-s2.0-85043362481&partnerID=MN8TOARS.
    10.1016/j.neulet.2018.02.066
  21. Machado-Pereira, M.; Santos, T.; Ferreira, L.; Bernardino, L.; Ferreira, R.. "Challenging the great vascular wall: Can we envision a simple yet comprehensive therapy for stroke?". Journal of Tissue Engineering and Regenerative Medicine 12 1 (2018): e350-e354. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020466929&partnerID=MN8TOARS.
    10.1002/term.2427
  22. Saraiva, C.; Talhada, D.; Rai, A.; Ferreira, R.; Ferreira, L.; Bernardino, L.; Ruscher, K.. "MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo". PLoS ONE 13 3 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85042940584&partnerID=MN8TOARS.
    10.1371/journal.pone.0193609
  23. Ferreira, A.C.; Santos, T.; Sampaio-Marques, B.; Novais, A.; Mesquita, S.D.; Ludovico, P.; Bernardino, L.; et al. "Lipocalin-2 regulates adult neurogenesis and contextual discriminative behaviours". Molecular Psychiatry 23 4 (2018): 1031-1039. http://www.scopus.com/inward/record.url?eid=2-s2.0-85038012215&partnerID=MN8TOARS.
    10.1038/mp.2017.95
  24. S. Barata-Antunes; A.C. Cristóvão; J. Pires; S.M. Rocha; L. Bernardino. "Dual role of histamine on microglia-induced neurodegeneration". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1863 3 (2017): 764-769. https://doi.org/10.1016/j.bbadis.2016.12.016.
    10.1016/j.bbadis.2016.12.016
  25. Machado-Pereira, M.; Santos, T.; Bernardino, L.; Ferreira, R.. "Vascular inter-regulation of inflammation: molecular and cellular targets for CNS therapy". Journal of Neurochemistry 140 5 (2017): 692-702. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013800733&partnerID=MN8TOARS.
    10.1111/jnc.13914
  26. Ana Raquel Santiago; Liliana Bernardino; Marta Agudo-Barriuso; Joana Gonçalves. "Microglia in Health and Disease: A Double-Edged Sword". Mediators of Inflammation (2017):
    10.1155/2017/7034143
  27. Saraiva, C.; Esteves, M.; Bernardino, L.. "MicroRNA: Basic concepts and implications for regeneration and repair of neurodegenerative diseases". Biochemical Pharmacology 141 (2017): 118-131. http://www.scopus.com/inward/record.url?eid=2-s2.0-85025474702&partnerID=MN8TOARS.
    10.1016/j.bcp.2017.07.008
  28. Valero, J.; Bernardino, L.; Cardoso, F.L.; Silva, A.P.; Fontes-Ribeiro, C.; Ambrósio, A.F.; Malva, J.O.. "Impact of Neuroinflammation on Hippocampal Neurogenesis: Relevance to Aging and Alzheimer's Disease". Journal of Alzheimer's Disease 60 s1 (2017): S161-S168. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029488785&partnerID=MN8TOARS.
    10.3233/JAD-170239
  29. Aday, S.; Zoldan, J.; Besnier, M.; Carreto, L.; Saif, J.; Fernandes, R.; Santos, T.; et al. "Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition". Nature Communications 8 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85030330994&partnerID=MN8TOARS.
    10.1038/s41467-017-00746-7
  30. Santos, T.; Ferreira, R.; Quartin, E.; Boto, C.; Saraiva, C.; Bragança, J.; Peça, J.; et al. Autor correspondente: Bernardino, L.. "Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles". Acta Biomaterialia 59 (2017): 293-302. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021825481&partnerID=MN8TOARS.
    10.1016/j.actbio.2017.06.044
  31. Marta Machado-Pereira; Tiago Santos; Lino Ferreira; Liliana Bernardino; Raquel Ferreira. "Anti-Inflammatory Strategy for M2 Microglial Polarization Using Retinoic Acid-Loaded Nanoparticles". Mediators of Inflammation (2017):
    10.1155/2017/6742427
  32. Fonseca, B.M.; Rodrigues, M.; Cristóvão, A.C.; Gonçalves, D.; Fortuna, A.; Bernardino, L.; Falcão, A.; Alves, G.. "Determination of catecholamines and endogenous related compounds in rat brain tissue exploring their native fluorescence and liquid chromatography". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1049-1050 (2017): 51-59. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014362163&partnerID=MN8TOARS.
    10.1016/j.jchromb.2017.02.028
  33. Cláudia Saraiva; Catarina Praça; Raquel Ferreira; Tiago Santos; Lino Ferreira; Liliana Bernardino. "Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases". Journal of Controlled Release 235 (2016): 34-47. https://doi.org/10.1016%2Fj.jconrel.2016.05.044.
    10.1016/j.jconrel.2016.05.044
  34. Saraiva, C.; Paiva, J.; Santos, T.; Ferreira, L.; Bernardino, L.. "MicroRNA-124 loaded nanoparticles enhance brain repair in Parkinson's disease". Journal of Controlled Release 235 (2016): 291-305. http://www.scopus.com/inward/record.url?eid=2-s2.0-84974633324&partnerID=MN8TOARS.
    10.1016/j.jconrel.2016.06.005
  35. Rocha, S.M.; Saraiva, T.; Cristóvão, A.C.; Ferreira, R.; Santos, T.; Esteves, M.; Saraiva, C.; et al. Autor correspondente: Bernardino, L.. "Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation". Journal of Neuroinflammation 13 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84973169252&partnerID=MN8TOARS.
    10.1186/s12974-016-0600-0
  36. Rosa, A.I.; Grade, S.; Santos, S.D.; Bernardino, L.; Chen, T.C.; Relvas, J.; Hofman, F.M.; Agasse, F.. "Heterocellular contacts with mouse brain endothelial cells via laminin and a6ß1 integrin sustain subventricular zone (SVZ) stem/progenitor cells properties". Frontiers in Cellular Neuroscience 10 DEC2016 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85007483072&partnerID=MN8TOARS.
    10.3389/fncel.2016.00284
  37. Santos, T.; Boto, C.; Saraiva, C.M.; Bernardino, L.; Ferreira, L.. "Nanomedicine Approaches to Modulate Neural Stem Cells in Brain Repair". Trends in Biotechnology 34 6 (2016): 437-439. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964372743&partnerID=MN8TOARS.
    10.1016/j.tibtech.2016.02.003
  38. Ferreira, R.; Fonseca, M.C.; Santos, T.; Sargento-Freitas, J.; Tjeng, R.; Paiva, F.; Castelo-Branco, M.; Ferreira, L.S.; Bernardino, L.. "Retinoic acid-loaded polymeric nanoparticles enhance vascular regulation of neural stem cell survival and differentiation after ischaemia". Nanoscale 8 15 (2016): 8126-8137. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964645621&partnerID=MN8TOARS.
    10.1039/c5nr09077f
  39. Tenreiro, M.M.; Ferreira, R.; Bernardino, L.; Brito, M.A.. "Cellular response of the blood-brain barrier to injury: Potential biomarkers and therapeutic targets for brain regeneration". Neurobiology of Disease 91 (2016): 262-273. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962311044&partnerID=MN8TOARS.
    10.1016/j.nbd.2016.03.014
  40. Saraiva, C.; Ferreira, L.; Bernardino, L.. "Traceable microRNA-124 loaded nanoparticles as a new promising therapeutic tool for Parkinson’s disease". Neurogenesis 3 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85050580278&partnerID=MN8TOARS.
    10.1080/23262133.2016.1256855
  41. Esteves, M.; Cristóvão, A.C.; Saraiva, T.; Rocha, S.M.; Baltazar, G.; Ferreira, L.; Bernardino, L.. "Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model for parkinson's disease". Frontiers in Aging Neuroscience 7 MAR (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84926392573&partnerID=MN8TOARS.
    10.3389/fnagi.2015.00020
  42. Ferreira, R.; Bernardino, L.; BERNARDINO, LILIANA. "Dual role of microglia in health and disease: Pushing the balance toward repair". Frontiers in Cellular Neuroscience 9 FEB (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84923247654&partnerID=MN8TOARS.
    10.3389/fncel.2015.00051
  43. Serpa, A.; Pinto, I.; Bernardino, L.; Cascalheira, J.F.. "Combined neuroprotective action of adenosine A1 and cannabinoid CB1 receptors against NMDA-induced excitotoxicity in the hippocampus". Neurochemistry International 87 (2015): 106-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937630250&partnerID=MN8TOARS.
    10.1016/j.neuint.2015.06.005
  44. Eiriz, M.F.; Valero, J.; Malva, J.O.; Bernardino, L.. "New insights into the role of histamine in subventricular zone-olfactory bulb neurogenesis". Frontiers in Neuroscience 8 JUN (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84905001204&partnerID=MN8TOARS.
    10.3389/fnins.2014.00142
  45. Xapelli, S.; Agasse, F.; Grade, S.; Bernardino, L.; Ribeiro, F.F.; Schitine, C.S.; Heimann, A.S.; et al. "Modulation of subventricular zone oligodendrogenesis: A role for hemopressin?". Frontiers in Cellular Neuroscience 8 FEB (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84901347333&partnerID=MN8TOARS.
    10.3389/fncel.2014.00059
  46. Rocha, S.M.; Pires, J.; Esteves, M.; Baltazar, G.; Bernardino, L.. "Histamine: A new immunomodulatory player in the neuron-glia crosstalk". Frontiers in Cellular Neuroscience 8 1 APR (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84899699754&partnerID=MN8TOARS.
    10.3389/fncel.2014.00120
  47. Grade, S.; Bernardino, L.; Malva, J.O.. "Oligodendrogenesis from neural stem cells: Perspectives for remyelinating strategies". International Journal of Developmental Neuroscience 31 7 (2013): 692-700. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887612588&partnerID=MN8TOARS.
    10.1016/j.ijdevneu.2013.01.004
  48. Agasse, F.; Xapelli, S.; Coronas, V.; Christiansen, S.H.; Rosa, A.I.; Sardá-Arroyo, L.; Santos, T.; et al. "Galanin promotes neuronal differentiation in murine subventricular zone cell cultures". Stem Cells and Development 22 11 (2013): 1693-1708. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878051807&partnerID=MN8TOARS.
    10.1089/scd.2012.0161
  49. Xapelli, S.; Agasse, F.; Sardà-Arroyo, L.; Bernardino, L.; Santos, T.; Ribeiro, F.F.; Valero, J.; et al. "Activation of Type 1 Cannabinoid Receptor (CB1R) Promotes Neurogenesis in Murine Subventricular Zone Cell Cultures". PLoS ONE 8 5 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84877955877&partnerID=MN8TOARS.
    10.1371/journal.pone.0063529
  50. Ferreira, R.; Santos, T.; Bernardino, L.. "Novel role of neuropeptide y in the modulation of microglia activity". Advances in Neuroimmune Biology 4 3 (2013): 167-176. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896741571&partnerID=MN8TOARS.
    10.3233/NIB-130063
  51. Santos, T.; Ferreira, R.; Maia, J.; Agasse, F.; Xapelli, S.; Cortes, L.; Bragancia, J.; et al. Autor correspondente: Bernardino, L.. "Polymeric nanoparticles to control the differentiation of neural stem cells in the subventricular zone of the brain". ACS Nano 6 12 (2012): 10463-10474. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871596644&partnerID=MN8TOARS.
    10.1021/nn304541h
  52. Santos, T.; Maia, J.; Agasse, F.; Xapelli, S.; Ferreira, L.; Bernardino, L.. "Nanomedicine boosts neurogenesis: New strategies for brain repair". Integrative Biology (United Kingdom) 4 9 (2012): 973-981. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870939373&partnerID=MN8TOARS.
    10.1039/c2ib20129a
  53. Ferreira, R.; Santos, T.; Gonçalves, J.; Baltazar, G.; Ferreira, L.; Agasse, F.; Bernardino, L.. "Histamine modulates microglia function". Journal of Neuroinflammation 9 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84860618694&partnerID=MN8TOARS.
    10.1186/1742-2094-9-90
  54. Bernardino, L.; Eiriz, M.F.; Santos, T.; Xapelli, S.; Grade, S.; Rosa, A.I.; Cortes, L.; et al. "Histamine stimulates neurogenesis in the rodent subventricular zone". Stem Cells 30 4 (2012): 773-784. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859512101&partnerID=MN8TOARS.
    10.1002/stem.1042
  55. Baptista, S.; Bento, A.R.; Gonçalves, J.; Bernardino, L.; Summavielle, T.; Lobo, A.; Fontes-Ribeiro, C.; et al. "Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures.". Neuropharmacology 62 7 (2012): 2413-2423. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871869687&partnerID=MN8TOARS.
    10.1016/j.neuropharm.2012.02.015
  56. Ferreira, R.; Santos, T.; Viegas, M.; Cortes, L.; Bernardino, L.; Vieira, O.V.; Malva, J.O.. "Neuropeptide Y inhibits interleukin-1ß-induced phagocytosis by microglial cells". Journal of Neuroinflammation 8 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-82455168238&partnerID=MN8TOARS.
    10.1186/1742-2094-8-169
  57. Eiriz, M.F.; Grade, S.; Rosa, A.; Xapelli, S.; Bernardino, L.; Agasse, F.; Malva, J.O.. "Functional evaluation of neural stem cell differentiation by single cell calcium imaging". Current Stem Cell Research and Therapy 6 3 (2011): 288-296. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051759924&partnerID=MN8TOARS.
    10.2174/157488811796575387
  58. Grade, S.; Agasse, F.; Bernardino, L.; Silva, C.G.; Cortes, L.; Malva, J.O.. "Functional identification of neural stem cell-derived oligodendrocytes by means of calcium transients elicited by thrombin". Rejuvenation Research 13 1 (2010): 27-37. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949493309&partnerID=MN8TOARS.
    10.1089/rej.2009.0889
  59. Rosa, A.I.; Gonçalves, J.; Cortes, L.; Bernardino, L.; Malva, J.O.; Agasse, F.. "The angiogenic factor angiopoietin-1 is a proneurogenic peptide on subventricular zone stem/progenitor cells". Journal of Neuroscience 30 13 (2010): 4573-4584. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950633340&partnerID=MN8TOARS.
    10.1523/JNEUROSCI.5597-09.2010
  60. BERNARDINO, LILIANA. "Malva JO, Bernardino L (2010) Células estaminais neurais: A caminho da reparação cerebral?". Canal BQ - Revista da Sociedade Portuguesa de Bioquímica 7 (2010):
    Publicado
  61. Bernardino, L.; Agasse, F.; Silva, B.; Ferreira, R.; Grade, S.; Malva, J.O.. "Tumor necrosis factor-a modulates survival, proliferation, and neuronal differentiation in neonatal subventricular zone cell cultures". Stem Cells 26 9 (2008): 2361-2371. http://www.scopus.com/inward/record.url?eid=2-s2.0-55049114476&partnerID=MN8TOARS.
    10.1634/stemcells.2007-0914
  62. Bernardino, L.; Balosso, S.; Ravizza, T.; Marchi, N.; Ku, G.; Randle, J.C.; Malva, J.O.; Vezzani, A.. "Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: A crucial role of P2X7 receptor-mediated IL-1ß release". Journal of Neurochemistry 106 1 (2008): 271-280. http://www.scopus.com/inward/record.url?eid=2-s2.0-45249094554&partnerID=MN8TOARS.
    10.1111/j.1471-4159.2008.05387.x
  63. Agasse, F.; Bernardino, L.; Kristiansen, H.; Christiansen, S.H.; Ferreira, R.; Silva, B.; Grade, S.; Woldbye, D.P.D.; Malva, J.O.. "Neuropeptide Y promotes neurogenesis in murine subventricular zone". Stem Cells 26 6 (2008): 1636-1645. http://www.scopus.com/inward/record.url?eid=2-s2.0-48649106084&partnerID=MN8TOARS.
    10.1634/stemcells.2008-0056
  64. Xapelli, S.; Bernardino, L.; Ferreira, R.; Grade, S.; Silva, A.P.; Salgado, J.R.; Cavadas, C.; et al. "Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: A role for microglia". European Journal of Neuroscience 27 8 (2008): 2089-2102. http://www.scopus.com/inward/record.url?eid=2-s2.0-42049112780&partnerID=MN8TOARS.
    10.1111/j.1460-9568.2008.06172.x
  65. Agasse, F.; Bernardino, L.; Silva, B.; Ferreira, R.; Grade, S.; Malva, J.O.. "Response to histamine allows the functional identification of neuronal progenitors, neurons, astrocytes, and immature cells in subventricular zone cell cultures". Rejuvenation Research 11 1 (2008): 187-200. http://www.scopus.com/inward/record.url?eid=2-s2.0-39449112119&partnerID=MN8TOARS.
    10.1089/rej.2007.0600
  66. Ravizza, T.; Lucas, S.-M.; Balosso, S.; Bernardino, L.; Ku, G.; Noé, F.; Malva, J.; et al. "Inactivation of caspase-1 in rodent brain: A novel anticonvulsive strategy". Epilepsia 47 7 (2006): 1160-1168. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746145901&partnerID=MN8TOARS.
    10.1111/j.1528-1167.2006.00590.x
  67. Bernardino, L.; Ferreira, R.; Cristóvão, A.J.; Sales, F.; Malva, J.O.. "Inflammation and neurogenesis in temporal lobe epilepsy". Current Drug Targets: CNS and Neurological Disorders 4 4 (2005): 349-360. http://www.scopus.com/inward/record.url?eid=2-s2.0-23144431758&partnerID=MN8TOARS.
    10.2174/1568007054546171
  68. Bernardino, L.; Xapelli, S.; Silva, A.P.; Jakobsen, B.; Poulsen, F.R.; Oliveira, C.R.; Vezzani, A.; Malva, J.O.; Zimmer, J.. "Modulator effects of interleukin-1ß and tumor necrosis factor-a on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures". Journal of Neuroscience 25 29 (2005): 6734-6744. http://www.scopus.com/inward/record.url?eid=2-s2.0-22544483518&partnerID=MN8TOARS.
    10.1523/JNEUROSCI.1510-05.2005
Capítulo de livro
  1. Bernardino, Liliana. "Histamine in the Crosstalk Between Innate Immune Cells and Neurons: Relevance for Brain Homeostasis and Disease". In Current Topics in Behavioral Neurosciences. Springer Berlin Heidelberg, 2021.
    10.1007/7854_2021_235
  2. Ferreira, Raquel; Bernardino, Liliana. "Nanotechnology for intracellular delivery and targeting". In Nanoengineered Biomaterials for Advanced Drug Delivery, 683-696. Elsevier, 2020.
    10.1016/b978-0-08-102985-5.00027-9
  3. BERNARDINO, LILIANA; Ferreira, Raquel. "Neurogenesis and the brain vasculature". In in: Advances in Brain Vascular Research, 28-47. Cambridge Scholars Publishing Ltd. England, 2020.
    Publicado
  4. Saraiva, Cláudia; Santos, Tiago; Bernardino, Liliana. "Neural Stem Cell-Based Therapeutic Approaches for Brain Repair". In Pathology, Prevention and Therapeutics of Neurodegenerative Disease, 241-252. Springer Singapore, 2018.
    10.1007/978-981-13-0944-1_21
  5. BERNARDINO, LILIANA. "Grade S, Rosa AI, Silva AC, Bernardino L, Malva JO, AC Rego (2017) Neurogénese e terapia celular do cérebro". In In: Neurociências. Edições Lidel., 2017.
  6. BERNARDINO, LILIANA. "Ferreira R, Bernardino L, Xapelli S (2017) Epilepsia". In In: Neurociências. Edições Lidel, 2017.
    Publicado
  7. Ferreira, R.; Ballerini, C.; Passani, Maria Beatrice; Bernardino, L.. "Histaminergic Regulation of Blood–Brain Barrier Activity". In Histamine Receptors, 215-230. Springer International Publishing, 2016.
    10.1007/978-3-319-40308-3_8
  8. Eiriz, Maria Francisca; Malva, João Oliveira; Agasse, Fabienne; Bernardino, Liliana. "Histamine in the Neural and Cancer Stem Cell Niches". In Stem Cells and Cancer Stem Cells, Volume 12, 3-17. Springer Netherlands, 2013.
    10.1007/978-94-017-8032-2_1
  9. BERNARDINO, LILIANA; João Malva. "Células estaminais neurais: A caminho da reparação cerebral?". In Canal BQ - Revista da Sociedade Portuguesa de Bioquímica, 24-29. Portugal, 2010.
    Publicado
  10. Bernardino, Liliana; Agasse, Fabienne; Malva, João O.. "Neurogenesis and Inflammation". In Encyclopedia of Neuroscience, 2676-2680. Springer Berlin Heidelberg, 2008.
    10.1007/978-3-540-29678-2_3847
  11. Malva, João O.; Bernardino, Liliana. "Inflammation and Neuronal Susceptibility to Excitotoxic Cell Death". In Interaction Between Neurons and Glia in Aging and Disease, 3-35. Springer US, 2007.
    10.1007/978-0-387-70830-0_1
  12. Agasse, Fabienne; Bernardino, Liliana; Malva, João O.. "Subventricular Zone Cells as a Tool for Brain Repair". In Interaction Between Neurons and Glia in Aging and Disease, 81-108. Springer US, 2007.
    Publicado • 10.1007/978-0-387-70830-0_4
Edição de livro
  1. Saraiva C, Ferreira R, Bernardino L. Research Topic - Stem cells & Brain injury: reprogramming, modeling and therapy. Frontiers in Cellular Neuroscience - section Cellular Neuropathology. 2022.
    Publicado • Editor
  2. Ferreira R, Cristóvão AC, BernardinoL. Advances in Brain Vascular Research. Cambridge Scholars Publishing Ltd. England. 2020.
    Publicado
  3. Ferreira, Raquel; Bernardino, Liliana; Passani, Maria Beatrice; Volonté, Cinzia. Dual Role of Microglia in Health and Disease: Pushing the Balance Towards Repair. Frontiers Media SA. 2020.
    Publicado • 10.3389/978-2-88966-106-0 • Editor
  4. Ana Raquel Santiago, Liliana Bernardino, Marta Agudo-Barriuso, Joana Gonçalves. Microglia in Health and Disease: A Double-Edged Sword. Mediators of Inflammation. 2017.
    Publicado • Editor
  5. Ferreira R, Bernardino L. Ferreira R, Bernardino L (2015) Dual role of microglia in health and disease: pushing the balance towards repair.. Ebook - Front. Cell. Neurosci. 2015.
    Publicado • Editor
Livro
  1. BERNARDINO, LILIANA; Ferreira, Raquel; Cristóvão, Ana Clara Braz. Advances in Brain Vascular Research. Cambridge Scholars Publishing Ltd. 2020.
    Publicado • Editor
Poster em conferência
  1. Cristovão ACC, Fiadeiro M, Sousa AC, Afonso M, Bernardino L, Neves M, Sharma M, Coutinho J, Freire M. "New formulation of NADPH Oxidase inhibitor to prevent neurodegeneration in Parkinson’s Disease". Trabalho apresentado em AD/PDTM 2022 International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders, 2022.
  2. Serra-Almeida C, Gomez Giro G, Saraiva S, Cristovao AC, Schwamborn JS, Bernardino L. "Studying the role of microRNAs in autophagy in human midbrain organoids carrying the SNCA triplication.". Trabalho apresentado em Synuclein Meeting, 2022.
  3. Esteves M, Abreu R, Fernandes H, Saraiva C, Ferreira R, Cristóvão AC, Ferreira L, Bernardino L. "MicroRNA-124 enriched exosomes induce neurogenesis and counteract dopaminergic degeneration and motor deficits in a Parkinson’s disease mouse model. 11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, October 10-12, Lisbon.". 2019.
  4. Serra-Almeida C, Saraiva C, Esteves M, Santos T, Ferreira R, Cristóvão AC, Bernardino L. "CtBPs Induce Neuronal and Oligodendrocyte Differentiation From Neural Stem Cells In The Subventricular Zone. 11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, October 10-12, Lisbon.". 2019.
  5. Brito V, Marques M, Alves G, Almeida P, Esteves M, Almeida C, Bernardino L, Silvestre S. "Synthesis and biological evaluation of new 16e-arylidende-5alpha,6alpha epoxydehydroepiandrosterone derivatives. III International Congress in Health Sciences Research - Trends in Aging and Cancer, November 14-16, Covilhã.". 2019.
    10.17758/iaast.a0714020
  6. Pais JP, Machado-Pereira M, Saraiva C, Bernardino L, Cristóvão AC, Ferreira R. "Argonaute-2 role in post-ischemia inflammatory response. III International Congress in Health Sciences Research - Trends in Aging and Cancer, November 14-16, Covilhã.". 2019.
  7. Machado-Pereira M, Pais JP, Bernardino L, Cristóvão AC, Ferreira R. "Putative therapeutic role of argonaute-2 in stroke. III International Congress in Health Sciences Research - Trends in Aging and Cancer, November 14-16, Covilhã. Best Poster award.". 2019.
  8. Almeida C, Saraiva C, Esteves M, Santos T, Ferreira R, Cristóvão AC, Bernardino L. "CtBPs: Novel transcriptional regulators of neural stem cells. XIV Annual CICS-UBI Symposium, University of Beira Interior, July 4-5.". 2019.
  9. Esteves M, Abreu R, Fernandes H, Saraiva C, Ferreira R, Cristóvão AC, Ferreira L, Bernardino L. "miR-124-enriched exosomes improve adult neurogenesis and protect dopaminergic neurons in Parkinson’s disease. XIV Annual CICS-UBI Symposium, University of Beira Interior, July 4-5.". 2019.
  10. BERNARDINO, LILIANA. "CtBPs as novel transcriptional regulators of neuronal and oligodendrocyte differentiation from neural stem cells. Conference Ageing: models, mechanisms and therapies. June 28-29, Coimbra.". 2019.
  11. BERNARDINO, LILIANA. "miR-124-enriched exosomes improve adult neurogenesis and protect dopaminergic neurons in Parkinson’s disease. Conference Ageing: models, mechanisms and therapies. June 28-29, Coimbra.". 2019.
  12. Esteves M, Abreu R, Fernandes H, Saraiva C, Ferreira R, Cristóvão AC, Ferreira L, Bernardino L.. "MicroRNA-124-enriched exosomes improve adult neurogenesis in the subventricular zone. XVI Meeting of the Portuguese Society for Neuroscience (SPN), Lisboa, May 30th-June 1st.". 2019.
  13. Almeida CA, Saraiva C, Esteves M, Santos T, Ferreira R, Cristóvão AC, Bernardino L. "CTBPS: novel transcriptional regulators of neurogenesis. XVI Meeting of the Portuguese Society for Neuroscience (SPN), Lisboa, May 30th-June 1st.". 2019.
  14. 6. Pais JP, Machado-Pereira M, Saraiva C, Bernardino L, Cristóvão AC, Ferreira R. "Argonaute-2 role in post-ischemia inflammatory response". Trabalho apresentado em III International Congress in Health Sciences Research - Trends in Aging and Cancer, Covilhã, 2019.
  15. Brito V, Marques M, Alves G, Almeida P, Esteves M, Almeida C, Bernardino L, Silvestre S. "Synthesis and biological evaluation of new 16e-arylidende-5alpha,6alpha epoxydehydroepiandrosterone derivatives.". Trabalho apresentado em III International Congress in Health Sciences Research - Trends in Aging and Cancer, Covilhã, 2019.
  16. Serra-Almeida C, Saraiva C, Esteves M, Santos T, Ferreira R, Cristóvão AC, Bernardino L. "CtBPs Induce Neuronal and Oligodendrocyte Differentiation From Neural Stem Cells In The Subventricular Zone". Trabalho apresentado em 11º Encontro Anual da Sociedade Portuguesa de Células Estaminais e Terapia Celular (SPCE-TC), 2019.
  17. Esteves M, Abreu R, Fernandes H, Saraiva C, Ferreira R, Cristóvão AC, Ferreira L, Bernardino L. "MicroRNA-124 enriched exosomes induce neurogenesis and counteract dopaminergic degeneration and motor deficits in a Parkinson’s disease mouse model.". Trabalho apresentado em 11º Encontro Anual da Sociedade Portuguesa de Células Estaminais e Terapia Celular (SPCE-TC), 2019.
  18. Saraiva C, Rai A, Talhada D, Santos T, Ferreira R, Ferreira L, Rusher K, Bernardino L. "Targeting subventricular zone neurogenesis in Parkinson’s disease and stroke animal models using microRNA-124-loaded nanoparticles. 11th FENS Forum of Neuroscience, Berlin, July 7-11.". 2018.
  19. Saraiva C, Talhada D, Rai A, Ferreira R, Ferreira L, Bernardino L, Ruscher K. "microRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo. Congress “10th International meeting of the Portuguese Society for Stem cells and Cell therapies”, Covilhã, October 12-14.". 2018.
  20. Barata-Antunes S, Cristóvão AC, Machado-Pereira M, Santos T, Saraiva C, Ferreira R, Bernardino L. "Unveiling a novel crosstalk between histamine and lipopolysaccharide in the modulation of inflammation and neurogenesis in the hippocampus. I Simpósio em Bioquímica Aplicada. Braga, May 31th.". 2017.
  21. Nunes J, Afonso M, Santos T, Esteves M, Cristóvão AC, Bernardino L. "Novel transcriptional regulation mechanisms associated with Parkinson’s disease pathogenesis. II International Congress in Health Sciences Research. Towards Innovation and entrepreneurship: Trends in Biotechnology for Biomedical Applications. Covilhã. May 17-20.". 2017.
  22. Pereira M, Santos T, Ferreira L, Bernardino L, Ferreira R. "Anti-inflammatory strategy for M2 microglial polarization using retinoic acid-loaded nanoparticles. Jornadas de Biomédicas, University of Beira Interior, Covilhã, March 8-11.". 2017.
  23. Machado-Pereira M, Santos T, Ferreira L, Bernardino L, Ferreira R. "Anti-inflammatory strategy for M2 microglial polarization using retinoic acid-loaded nanoparticles. V Jornadas de Química e Bioquímica. University of Beira Interior, Covilhã. May 3-4.". 2017.
  24. Bernardino L, Eiriz MF, Santos T, Xapelli S, Grade S, Rosa AI, Cortes L, Ferreira R, Bragança J, Agasse F, Ferreira L, M. "Histamine Stimulates Neurogenesis in the Rodent Subventricular Zone. International Meeting on Stem Cells for Regenerative Medicine and Drug Screening, Biocant, Cantanhede, July 19th.". 2013.
  25. Santos T, Ferreira R, Maia J, Agasse F, Xapelli S, Cortes L, Bragança J, Malva JO, Ferreira L, Bernardino L. "Polymeric Nanoparticles to Control the Differentiation of Neural Stem Cells in the Subventricular Zone of the Brain. International Meeting on Stem Cells for Regenerative Medicine and Drug Screening, Biocant, Cantanhede, July 19th.". 2013.
  26. Bernardino L, Eiriz MF, Santos T, Xapelli S, Grade S, Rosa A, Cortes L, Bragança J, Agasse F, Ferreira L, Malva JO. "Histamine as a promising proneurogenic factor on subventricular zone stem cells: a new approach for brain repair. Congress “8th IBRO World Congress of Neuroscience”, Florence, Italy, July 14-18.". 2011.
  27. Bernardino L, Eiriz MF, Santos T, Xapelli S, Grade S, Rosa A, Cortes L, Bragança J, Agasse F, Ferreira L, Malva JO. "Histamine, a proneurogenic factor on the subventricular zone: a new approach for brain repair. Congress “10th European meeting on glial cells in health and disease”, Praga, September 13-17.". 2011.
  28. Baptista S, Bento AR, Gonçalves J, Bernardino L, Ribeiro CR, Malva JO, Agasse F, Silva AP. "Neuropeptide Y Promotes Neurogenesis and Protection Against Methamphetamine-Induced Toxicity in Dentate Gyrus Cell Cultures. Congress “23rd Biennial Meeting ISN-ESN 2011”, Athens, Greece, August 28th – September 1st.". 2011.
    10.1109/bsc.2006.1644552
  29. Ferreira R, Santos T, Agasse F, Malva JO, Bernardino L. "Histamine modulates the inflammatory response of microglial cells. Congress “10th European meeting on glial cells in health and disease”, Praha, September 13-17.". 2011.
  30. Xapelli S, Sardà-Arroyo L, Bernardino L, Santos T, Schitine C, Agasse F, Malva JO.. "Activation of the cannabinoid CB1R promotes proliferation and neuronal differentiation in murine subventricular zone cell cultures. Congress “10th European meeting on glial cells in health and disease”, Praha, September 13-17.". 2011.
  31. Xapelli S, Sardà L, Bernardino L, Santos S, Schitine CS, Cortes L, De Melo Reis RA, Agasse F, Malva JO. "The endocannabinoid system promotes proliferation and neuronal differentiation in murine subventricular zone cell cultures. Congress “8th IBRO World Congress of Neuroscience”, Florence, Italy, July 14-18.". 2011.
  32. Baptista S, Bento AR, Gonçalves J, Bernardino L, Fontes Ribeiro C, Malva JO, Agasse F, Silva AP. "Methamphetamine impairs neurogenesis in dentate gyrus cell cultures: protective role of neuropeptide Y. Congress “8th IBRO World Congress of Neuroscience”, Florence, Italy, July 14-18.". 2011.
  33. Santos T, Ferreira R, Maia J, Xapelli S, Cortes L, Agasse F, Bragança J, Ferreira L, Malva JO, Bernardino L. "Neuronal Differentiation of Neural Stem Cells by a Novel Retinoic Acid-Loaded Nanoparticles Delivery System. Congress “8th IBRO World Congress of Neuroscience”, Florence, Italy, July 14-18.". 2011.
  34. Ferreira R, Santos T, Agasse F, Malva JO, Bernardino L. "Histamine modulates microglial inflammatory response. Congress “8th IBRO World Congress of Neuroscience”, Florence, Italy, July 14-18.". 2011.
  35. Ferreira R, Santos T, Agasse F, Malva JO, Bernardino L. "Histamine modulates microglial inflammatory response. Congress “8th IBRO World Congress of Neuroscience”, Florence, Italy, July 14-18.". 2011.
  36. Maia J, Santos T, Aday S, Agasse F, Cortes L, Malva JO, Bernardino L, Ferreira L. "Controlling the Neuronal Differentiation of Stem Cells by the Intracellular Delivery of Retinoic Acid-loaded Nanoparticles. Congress “European Society of Biomaterials (ESB)”, Dublin, September 4-8.". 2011.
  37. Baptista S, Bento AR, Gonçalves J, Bernardino L, Ribeiro CF, Malva JO, Agasse F, Silva AP. "Methamphetamine is toxic and impairs neurogenesis in dentate gyrus cell cultures. Congress “6th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies (SPCE-TC)”, Biocant- Cantanhede, April 28-29.". 2011.
  38. Xapelli s, de Melo Reis RA, Bernardino L, Agasse F, Schitine CS, Cortes L, Heimann A, Ferro ES, Malva JO.. "Endocannabinois mediate neurogenesis in murine subventricular zone Stem/Progenitor Cell Cultures. Congress “6th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies (SPCE-TC)”, Biocant- Cantanhede, April 28-29.". 2011.
  39. Santos T, Ferreira R, Maia J, Xapelli S, Cortes L, Agasse F, Bragança J, Ferreira L, Malva JO, Bernardino L. "Retinoic Acid-Loaded Nanoparticles Induce Neuronal Differentiation of Neural Stem cells. “12th Annual Meeting of the Portuguese Society for Neuroscience (SPN)”, Lisboa, May 26-28.". 2011.
  40. Xapelli S, Sardà L, Agasse F, Bernardino L, Santos T, DE Melo Reis RA, Schitine CS, Cortes L, Heimann A, Ferro ES, Malva. "The endocannabinoid system mediates neuronal differentiation in murine subventricular zone stem/progenitor cell cultures. “12th Annual Meeting of the Portuguese Society for Neuroscience (SPN)”, Lisboa, May 26-28.". 2011.
  41. Bernardino L, Eiriz MF, Santos T, Xapelli S, Grade S, Rosa A, Cortes L, Bragança J, Agasse F, Ferreira L, Malva JO. "Histamine as a proneurogenic factor on subventricular zone: a new approach for brain repair therapies. “12th Annual Meeting of the Portuguese Society for Neuroscience (SPN)”, Lisboa, May 26-28". 2011.
  42. Bernardino L, Eiriz MF, Xapelli S, Grade S, Rosa A, Cortes L, Agasse F, Ferreira F, Malva JO. "Histamine is a Proneurogenic Factor on Subventricular Zone Stem/Progenitor Cells: A New Approach for Brain Repair Therapies. Congress “ISDN 2010- Understanding the basic mechanisms of neurodevelopmental disorders”, Estoril, Portugal, June 6-9.". 2010.
  43. Eiriz MF, Bernardino L, Xapelli S, Grade S, Rosa A, Cortes L, Agasse F, Ferreira L, Malva JO. "Histamine-releasing PLGA microparticles as a tool to impel brain repair. Congress “ESTOOLS- International Symposium: Stem Cells in Biology and Disease”, Lisboa, Portugal, May 26-28.". 2010.
  44. Xapelli S, Bernardino L, Cortes L, Schitine C, Ferro ES, De Melo Reis RA, Agasse F, Malva JO. "Activation of type 1 cannabinoid receptor (CB1R) induce neurogensis in the murine subventricular zone. Congress “ESTOOLS- International Symposium: Stem Cells in Biology and Disease”, Lisboa, Portugal, May 26-28.". 2010.
  45. Xapelli S, Bernardino L, Cortes L, Schitine C, Ferro E, De Melo Reis RA, Agasse F, Malva JO. "Type 1 Cannabinoid Receptor Activation Induces Neuronal Differentiation of Subventricular Zone Stem/Progenitor Cell Cultures. Congress “ISDN 2010- Understanding the basic mechanisms of neurodevelopmental disorders”, Estoril, Portugal, June 6-9.". 2010.
  46. Santos T, Maia J, Aday S, Bernardino L, Malva JO, Ferreira L. "Nanomaterials to drive the differentiation of stem cells into neuronal cells. Congress “ESTOOLS- International Symposium: Stem Cells in Biology and Disease”, Lisboa, Portugal, May 26-28.". 2010.
  47. Grade S, Agasse F, Bernardino L, Silva CG, Cortes L, Malva JO. "Functional identification of neural stem cell-derived oligodendrocytes by means of calcium transients elicited by thrombin. “La 3º Journée de la recherché du Regroupement Neurosciences & Santé Mentale de l’Université Laval », Quebéc city, Quebéc, November 26th.". 2009.
  48. Grade S, Agasse F, Bernardino L, Silva CG, Cortes L, Malva JO. "L'augmentation du calcium intracellulaire induit par la thrombine est caractéristique des oligodendrocytes provenant de cellules de la zone sous-ventriculaire. « Journée Scientifique du Centre de recherche Université Laval Robert-Giffard », Quebéc city, Quebéc, January 29th.". 2009.
  49. Xapelli S, Bernardino L, Ferreira R, Grade S, Silva AP, Cavadas C, Grouzmann E, Poulsen FR, Jakobsen B, Oliveira CR, Zim. "Interactions between NPY and BDNF in neuroprotection against excitotoxicity: a role for neuron-microglia crosstalk? 10th Annual Meeting of the Portuguese Society for Neuroscience (SPN), Ofir, Portugal, May 23-26.". 2007.
  50. Agasse F, Bernardino L, Ferreira R, Grade S, Silva BA, Malva JO.. "NPY modulates neurogenesis in SVZ cell cultures. 10th Annual Meeting of the Portuguese Society for Neuroscience (SPN), Ofir, Portugal, May 23-26.". 2007.
  51. Bernardino L, Agasse F, Grade S, Xapelli S, Ferreira R, Domingues S, Silva AP, Silva B, Oliveira CR, Malva JO.. "‘Neuroinflammation and Excitotoxicity in Temporal Lobe Epilepsy.’, XXI Annual Meeting of the Society of Experimental Biology, Aguas de Lindóia, São Paulo, Brasil, August 23-26.". 2006.
  52. Bernardino L, Balosso S, Ravizza T, Xapelli S, Ku G, Randle JC, Zimmer J, Dinarello C, Malva JO, and Vezzani A. "“Inflammation exacerbate excitotoxic injury in CA3 pyramidal neurons via Interleukin-1 beta release in organotypic cultures of mouse hippocampal slices.”, Advanced Course (FENS/PENS Summer School) “The Brain as a target for inflammatory processes”, Berlin, Germany, May 14-20.". 2006.
  53. Xapelli S, Bernardino L, Silva AP, Salgado JR, Cavadas C, Grouzmann E, Poulsen FR, Jakobsen B, Oliveira CR, Zimmer J and. "“Implication of BDNF in the neuroprotective effect of NPY in mouse hippocampal slice cultures exposed to excitotoxic insults.”, 8th NPY meeting, St. Petersburg, Florida, U.S.A., April 22-26.". 2006.
  54. Ravizza T, Filippi F, Noe’ F, Bernardino L, Balosso S, Ku G, Malva JO, Randle JCR, Vezzani A.. "‘Caspase-1 inhibition protects from seizures by blocking interleukin-1 (IL-1) beta production in brain.‘, American Epilepsy Society and American Clinical Neurophysiology Society Joint Annual Meeting, Washington, DC, USA, December 2-6.". 2005.
  55. Xapelli S, Silva AP, Ferreira R, Bernardino L, Pinheiro P, Zimmer J, Oliveira CR and Malva JO.. "‘NPY Y1 and Y2 receptors activation can rescue neurons following the application of an excitotoxic insult with kainate in rat organotypic hippocampal slice cultures ‘, FENS Advanced Summer School “Neuro-glia interaction in aging and disease”, Ofir, Portugal, July 5-10". 2005.
  56. Balosso S, Bernardino L, Rizzi M, Calcagno E, Invernizzi R, Zimmer J, Malva JO and Vezzani A.. "“Functional interactions between TNF-alpha and glutamate in the mouse hippocampus”. FENS Advanced Summer School “Neuro-glia interaction in aging and disease”, Ofir, Portugal, July 5-10.". 2005.
  57. Bernardino L, Balosso S, Ravizza T, Rizzi M, Ku G, Randle JC, Zimmer J, Malva JO and Vezzani A. "‘Involvement of P2X7 receptors in microglia-like cell death mediated by ATP in LPS-primed mouse organotypic hippocampal slice cultures.’ FENS Advanced Summer School: “Neuro-glia interaction in aging and disease”, Ofir, July 5-10.". 2005.
  58. Balosso S, Bernardino L, Ravizza T, Calcagno E, Ravizza T, Rizzi M, Zimmer J, Invernizzi R, Malva JO and Vezzani A. "’Functional interactions between TNF-alpha and glutamate in the hippocampus: implications for neuronal excitability and neuronal survival.’, Conference ” Molecular mechanisms of neurodegeneration”, Milan, Italy, May 7-10.". 2005.
  59. Bernardino L, Balosso S, Rizzi M, Marchi N, Ravizza T, Ku G, Randle JCR, Zimmer J, Malva JO, and Vezzani A.. "‘Inflammation induced in organotypic hippocampal slice cultures triggers microglia apoptosis mediated by TNF-alpha release.’, Conference ” Molecular mechanisms of neurodegeneration”, Milan, Italy, May 7-10.". 2005.
  60. Xapelli S, Bernardino L, Poulsen FR, Jakobsen B, Zimmer J and Malva JO. "’A activação do receptor Y2 do NPY protege culturas organotípicas de hipocampo de murganho contra agressões excitotóxicas.’, IV Congress of Investigation in Medicine ´Pedagogy and Science´, Coimbra, Portugal, November 17-18.". 2004.
  61. Xapelli S, Bernardino L, Poulsen FR, Jakobsen B, Zimmer J and Malva JO.. "‘Effect of neuropeptide Y2 receptor activation in AMPA-mediated neuronal death and Brain Derived Neurotrophic Factor expression in mouse organotypic hippocampal slice cultures.’ FEBS Course ‘New molecular strategies to treat neurodegenerative diseases’, Ofir, Portugal, July 17-23.". 2004.
  62. Xapelli S, Bernardino L, Silva AP, Jakobsen B, Zimmer J and Malva JO. "’Activaction of Neuropeptide Y2 and Y5 receptor is neuroprotective against excitotoxicity induced by AMPA in mouse organotypic hippocampal slice cultures.’,“7th international NPY meeting”; Hotel Melia, Coimbra, Portugal, February 3-7. Award for the best poster". 2004.
  63. Xapelli S, Bernardino L, Poulsen FR, Jakobsen B, Zimmer J and Malva JO. "’Neuropeptide Y2 receptor activation protect mouse organotypic hippocampal slice cultures against excitotoxic insults.’, Congress “The multiple facets of GABAergic synapses”; La Ciotat, France, September 15-18.". 2004.
  64. Xapelli S, Bernardino L, Silva AP, Poulsen FR, Jakobsen B, Oliveira CR, Malva JO and Zimmer J.. "’Involvement of neuropeptide Y2 receptor in neuroprotection and decrease of brain derived neurotrophic factor expression under excitotoxicity in mouse organotypic hippocampal slice cultures.’ XIV Annual Meeting of the Portuguese Biochemical Socieety, Vilamoura, Portugal, December 2-4.". 2004.
  65. Saavedra A, Bernardino L, Baltazar G and Duarte EP. "´Oxidative stress and GDNF expression and release in postnatal cultures from substantia nigra.´, ´Frontiers in Neurodegenerative Disorders and Aging: Fundamental Aspects, Clinical Perspectives and New Insights´, Antalya, Turquey, May 26th – June 1st.". 2003.
  66. Saavedra A, Bernardino L, Baltazar G, Carvalho C and Duarte EP.. "´GDNF expression in the nigrostriatal system: effect of damage to dopaminergic neurons.´ 8th Meeting of the Portuguese Society for Neurosciences, Curia, Portugal, June 12-13.". 2003.
Resumo em conferência
  1. BERNARDINO, LILIANA. "MicroRNA-124-3p-enriched Small Extracellular Vesicles as a Promising Therapeutic Approach for Parkinson’s Disease". Trabalho apresentado em Proceedings of the Nano Boston Conference. NanoWorld Journal, 2021.
    Publicado
  2. Rebelo C, Pinho S, Reis T, Saraiva C, Guedes J, Bernardino L, Peça J, Ferreira L. "NIR-light dependent delivery of Cre recombinase: an optogenetic tool for DNA modulation in the brain.". Trabalho apresentado em European Journal of Clinical Investigation., 2019.
    Publicado
  3. Aday S, Besnier M, Zoldan J, Saif J, Santos T, Carreto L, Bernardino L, Langer R, Emanueli C, Ferreira L.. "MicroRNA 17 in Angiogenesis: Lessons Learned From Immobilized Vascular Endothelial Growth Factor. Circulation Research 117:A10 • July 2015.". 2015.
  4. Aday S, Zoldan J, Carreto L, Santos T, Bernardino L, Malva J, Langer R, Ferreira L.. "VEGF165-bound beads modulate endothelial cell survival and mirna expression. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE. WILEY-BLACKWELL. 2014, 8:191-192.". 2014.
  5. Saraiva CM, Paiva JM, Ferreira L, Bernardino L.. "MicroRNA-124 loaded nanoparticles modulate neurogenesis in the subventricular zone. Program No. 199.12. 2014 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.". 2014.
  6. Bernardino L, Saraiva T, Cristóvão AC, Esteves M, Baltazar G, Rocha S. "Histamine triggers microglial phagocytosis. Congress “XI European Meeting on Glial Cell Function in Health and Disease”, July 3-6, Berlin. Special issue of Glia, Volume 61, Issue Supplement S1, July 2013; DOI: 10.1002/glia.22530.". 2013.
  7. Xapelli S, Sardà-Arroyo L, Bernardino L, Santos T, Schitine C, Agasse F, Malva JO.. "(R)-(+)-Methanandamide stimulates neurogenesis in neural stem/progenitor cell cultures derived from postnatal rodent subventricular zone. FENS, A-471-0001-00415, 2012.". 2012.
  8. Xapelli S, Agasse F, Bernardino L, Schitine CS, Heimann A, Ferro ES, De Melo Reis RA, Malva JO. "Hemopressin promotes neurogenesis and oligodendrogenesis in murine subventricular zone cell cultures. Program No. 33.06. 2012 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online.". 2012.
  9. Xapelli S, Agasse F, Ribeiro FF, Bernardino L, Schitine CS, Heimann A, Ferro ES, De Melo Reis RA, Sebastião AM, Malva JO. "Hemopressin promotes oligodendrogenesis in murine subventricular zone cell cultures J Neurochem 125(Supplement s1) Special Issue: The 24th Biennial Meeting of the International Society for Neurochemistry and the American Society for Neurochemistry.". 2012.
  10. Ferreira R, Santos T, Agasse F, Malva JO, Bernardino L. "Histamine modulates the inflammatory response of microglial cells. Congress “10th European meeting on glial cells in health and disease”, Prague, September 13-17. GLIA 59:S42–S154 (2011) DOI: 10.1002/glia.21210, S42.". 2011.
    10.1158/1538-7445.am2017-lb-295
  11. Xapelli S, Sardà-Arroyo L, Bernardino L, Santos T, Schitine C, Agasse F, Malva JO.. "Activation of the cannabinoid CB1R promotes proliferation and neuronal differentiation in murine subventricular zone cell cultures. Congress “10th European meeting on glial cells in health and disease”, Prague, September 13-17. GLIA 59:S42–S154 (2011) DOI: 10.1002/glia.21210, S123.". 2011.
  12. Ferreiro F, Valero J, Bernardino L, Pereira C, Agasse F. "Impaired properties of stem/progenitor cells contribute to decreased neurogenesis in the triple transgenic mouse model of Alzheimer’s disease. Soc. Neurosci. Abstr., 241.09/E23. SFN Neuroscience 2011; Washington DC, 12-16 November.". 2011.
  13. Rosa AI, Santos S, Bernardino L, Chen TC, Relvas J, Hofman FM, Agasse F. "Heterocellular contacts with mouse brain endothelial cells via laminin-1 and a6ß1 integrin sustains subventricular zone (SVZ) stem/progenitor cells properties. Soc. Neurosci. Abstr., 30.20/A42. SFN Neuroscience 2011; Washington DC, November 12-16.". 2011.
  14. Baptista S, Bento AR, Gonçalves J, Bernardino L, Ribeiro CR, Malva JO, Agasse F, Silva AP. "Neuropeptide Y Promotes Neurogenesis and Protection Against Methamphetamine-Induced Toxicity in Dentate Gyrus Cell Cultures. Congress “23rd Biennial Meeting ISN-ESN 2011”, Athens, Greece, August 28th – September 1st. Journal of Neurochemistry, vol. 94, supplement 2, pag.180.". 2011.
  15. Bernardino L, Eiriz MF, Santos T, Xapelli S, Grade S, Rosa A, Cortes L, Bragança J, Agasse F, Ferreira L, Malva JO. "Histamine, a proneurogenic factor on the subventricular zone: a new approach for brain repair. Congress “10th European meeting on glial cells in health and disease”, Prague, September 13-17. GLIA 59:S42–S154 (2011) DOI: 10.1002/glia.21210, S119.". 2011.
  16. Malva JO, Bernardino L, Eiriz M, Xapelli S, Grade S, Rosa A. Cortes L, Agasse F, Ferreira L. "Histamine-releasing PLGA microparticles promote neuronal differentiation from neural stem cell cultures. Soc. Neurosci. Abstr., 738.2. Poster presented at the “40th Annual Meeting of the Society for Neuroscience”, San Diego, EUA, November 13-17.". 2010.
  17. Xapelli S, Melo Reis RA, Schitine CS, Cortes L, Heimann A, Ferro ES, Agasse F, Bernardino L, Malva JO. "Cannabinoid type 1 receptor-mediated modulation of murine subventricular zone neurogenesis. Soc. Neurosci. Abstr., 437.15. Poster presented at the “40th Annual Meeting of the Society for Neuroscience”, San Diego, EUA, November 13-17.". 2010.
  18. Baptista S, Bento AR, Gonçalves J, Bernardino L, Fontes Ribeiro C, Malva JO, Agasse F, Silva AP. "Neuropeptide Y promotes proliferation, neuronal differentiation and protection against methamphetamine-induced toxicity in dentate gyrus cultures. FENS Abstr., vol.5, 041.2. Poster presented at the “7th FENS Forum of European Neuroscience”, Amsterdam, The Netherlands, July 3-7.". 2010.
  19. BERNARDINO, LILIANA. "Type 1 cannabinoid receptor (CB1R) activation promotes neuronal differentiation in murine subventricular zone cell cultures. FENS Abstr., vol.5, 073.38. Poster presented at the “7th FENS Forum of European Neuroscience”, Amsterdam, The Netherlands, July 3-7.". 2010.
  20. BERNARDINO, LILIANA. "Histamine promotes neurogenesis in subventricular zone cell cultures: a new approach for brain repair therapies. FENS Abstr., vol.5, 011.6. Poster presented at the “7th FENS Forum of European Neuroscience”, Amsterdam, The Netherlands, July 3-7.". 2010.
  21. BERNARDINO, LILIANA. "Methamphetamine exerts toxic effects in murine subventricular zone cell cultures. Frontiers in Neuroscience. doi: 10.3389/conf.neuro.01.2009.11.050.". 2009.
  22. Baptista S, Bento AR, Bernardino L, Ribeiro CF, Malva JO, Agasse F, Silva AP. "Methamphetamine is toxic for murine dentate progenitor cell cultures. Frontiers in Neuroscience. doi: 10.3389/conf.neuro.01.2009.11.048. “11º Encontro Anual da Sociedade Portuguesa de Neurociências (SPN)”.". 2009.
  23. Agasse F, Christiansen SH, Rosa A, Schitine C, Bernardino L, Malva JO, Woldbye DPD. "Neuropeptides galanin and somatostatin promote neuronal differentiation in murine subventricular zone cultures. Frontiers in Neuroscience. doi: 10.3389/conf.neuro.01.2009.11.099.". 2009.
  24. Grade S, Agasse F, Bernardino L, Gomes C, Malva JO. "Thrombin-induced intracellular calcium rise identifies oligodendrocytes derived from SVZ cultures. Frontiers in Neuroscience. doi: 10.3389/conf.neuro.01.2009.11.014.". 2009.
  25. Grade S, Agasse F, Bernardino L, Silva CG, Cortes L, Malva. "Thrombin-induced intracellular calcium rise identifies oligodendrocytes derived from Subventricular Zone cell cultures. Soc. Neurosci. Abstr., 126.4. “39th Annual Meeting of the Society for Neuroscience”, Chicago, EUA.". 2009.
  26. Agasse F, Christiansen SH, Rosa A, Schitine C, Bernardino L, Malva JO, Woldbye DPD. "The neuropeptide Galanin promotes neuronal differentiation in murine subventricular zone cultures. Soc. Neurosci. Abstr., 30.5. “39th Annual Meeting of the Society for Neuroscience”, Chicago, EUA". 2009.
  27. Bernardino L, Eiriz MF, Santos T, Xapelli S, Grade S, Rosa A, Cortes L, Bragança J, Agasse F, Ferreira L, Malva JO. "Histamine induces neuronal differentiation in murine subventricular zone (SVZ) cell cultures. Frontiers in Neuroscience. doi: 10.3389/conf.neuro.01.2009.11.051.". 2009.
  28. Bernardino L, Eiriz MF, Xapelli S, Grade S, Cortes L, Agasse F, Ferreira F, Malva JO. "Histamine released from biocompatible microparticles induce neurogenesis in the murine subventricular zone. Soc. Neurosci. Abstr.,30.15. “39th Annual Meeting of the Society for Neuroscience”, Chicago, EUA.". 2009.
  29. Xapelli S, Bernardino L, Ferreira R, Grade S, Silva AP, Salgado JR, Cavadas C, Grouzmann E, Poulsen FR, Jakobsen B, Oliv. "Neuroprotective interactions between neuropeptide Y and brain-derived neurotrophic factor: a role for microglia. FENS Abstr., vol. 4, 115.21, 2008". 2008.
  30. Bernardino L, Agasse F, Silva BA, Ferreira R, Grade S, Malva JO.. "Modulator effects of tumor necrosis factor-alpha on subventricular zone neurogenesis. FENS Abstr., vol. 4, 009.2, 2008.". 2008.
  31. Bernardino L, Agasse F, Silva B, Ferreira R, Grade S, Malva JO. "Interplay between neurogenesis and neuroinflammation: Tumor Necrosis factor-alpha as a key modulator of SVZ neurogenesis in vitro. Program No. 522.6. 2008 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2008. Online.". 2008.
  32. Xapelli S, Bernardino L, Ferreira R, Grade S, Silva AP, Cavadas C, Grouzmann E, Poulsen F, Jakobsen B, Oliveira CR, Zimm. "Neuropeptide Y and brain derived neurotrophic factor in neuroprotection against excitotoxicity: A neuron-microglia crosstalk? J. Neurochem., vol. 102, pag. 229, supplement 1, 2007.". 2007.
  33. Bernardino L, Agasse F, Grade S, Ferreira R, Silva BA, Malva JO.. "Tumor necrosis factor-alpha modulates cell survival, proliferation and neuronal differentiation in neonatal neural stem cells. J. Neurochem. vol. 102, pag. 293, supplement 1, 2007.". 2007.
  34. Bernardino L, Agasse F, Silva BA, Grade S, Ferreira R, Malva JO.. "Role of TNF-alpha in neurogenesis: new potential tool for brain repair? Neuron Glia Biology, vol. 2, supplement 1, S79, A148, 2007.". 2007.
  35. Xapelli S, Bernardino L, Ferreira R, Grade S, Silva AP, Cavadas C, Grouzmann E, Poulsen F, Jakobsen B, Oliveira CR, Zimm. "Interaction between neurons and microglia in NPY and BDNF-mediated neuroprotection against excitotoxicity. Program No. 352.1. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online.". 2007.
  36. Agasse F, Bernardino L, Ferreira R, Grade S, Silva BA, Malva JO. "NPY promotes neurogenesis in subventricular zone (SVZ) cell cultures. Program No. 777.10. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online.". 2007.
  37. Bernardino L, Agasse F, Ferreira R, Grade S, Silva BA, Malva JO.. "Tumor Necrosis Factor-alpha promotes neuronal differentiation from Subventricular Zone cell cultures. Program No. 673.17. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online.". 2007.
  38. Agasse F, Bernardino L, Grade S, Silva AP, Ferreira R, Silva BA, Malva JO. "‘Subventricular zone (SVZ) cells as a tool for neuronal replacement in mice models of temporal lobe epilepsy.’36th Annual Meeting SFN; Atlanta, October 14-18. Program No. 221.8/A8. 2006 Neuroscience Meeting Planner. Atlanta, GA: Society for Neuroscience, 2006. Online.". 2006.
  39. Bernardino L, Agasse F, Grade S, Silva AP, Ferreira R, Silva BA, Malva JO. "‘Tumor necrosis factor-alpha induces differentiation of new neurons in neonatal subventricular zone cell cultures.’ 36th Annual Meeting SFN; Atlanta, October 14-18. Program No. 221.8/A8. 2006 Neuroscience Meeting Planner. Atlanta, GA: Society for Neuroscience, 2006. Online.". 2006.
  40. Malva JO, Bernardino L, Balosso S, Ravizza T, Marchi N, Ku G, Randle JC, Zimmer J, Dinarello C, Vezzani A. "‘Inflammation and interleukin–1beta release exacerbate excitotoxic damage to CA3 pyramidal neurons in mouse organotypic hippocampal slice cultures’ 5th Forum of European Neuroscience”, July 8-12, Vienna. FENS Abstr., vol.3, A202.8, 2006.". 2006.
  41. Ravizza T, Balosso S, Calcagno E, Rizzi M, Mariotto A, Bernardino L, Malva JO, Invernizzi R and Vezzani A. "‘Molecular and functional interactions between TNF-alpha and glutamate in the mouse hippocampus: implications for neuronal excitability and cell survival’ 35th Annual Meeting SFN; Washington DC, November 12-16. Program No. 906.4. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. Online.". 2005.
  42. Silva AP, Xapelli S, Ferreira R, Bernardino L, Pinheiro PS, Zimmer J, Oliveira CR, Malva JO. "“Activation of neuropeptide y1 or y2 receptors can prevent the excitotoxicity induced by kainate in rat organotypic hippocampal slice cultures” 35th Annual Meeting SFN; Washington DC, November 12-16. Program No. 336.16. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. Online.". 2005.
  43. Xapelli S, Bernardino L, Silva AP, Cavadas C, Grouzmann E, Poulsen FR, Jakobsen B, Cristóvão AJC, Oliveira CR, Zimmer J. "‘NPY triggers neuroprotection mechanisms following excitotoxic insults in mouse organotypic hippocampal slice cultures.’ 35th Annual Meeting SFN; Washington DC, November 12-16. Program No. 336.10. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. Online.". 2005.
  44. BERNARDINO, LILIANA. "‘Inflammatory stimuli in organotypic hippocampal slice cultures induces microglia-like cell apoptosis via P2X7 receptors: relevance for neuronal survival to excitotoxicity’ 35th Annual Meeting SFN; Washington DC, November 12-16, 2005, Program No. 906.6. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. Online.". 2005.
  45. Bernardino L, Xapelli S, Silva AP, Poulsen FR, Jakobsen B, Oliveira CR, Vezzani A, Malva JO and Zimmer J. ", ‘Distinct tumor necrosis factor-alpha receptor subtypes modulate neuronal survival in mouse organotypic hippocampal slice cultures.‘35th Annual Meeting SFN; Washington DC, November 12-16. Program No. 906.3. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. Online.". 2005.
  46. Bernardino L, Rizzi M, Marchi N, Ravizza T, Ku G, Randle JCR, Zimmer J, Malva JO, and Vezzani A. "’Adenosine Triphosphate induces microglia-like cell death in Lipopolysaccharide-primed mouse organotypic hippocampal slice cultures via Tumour Necrosis Factor-alpha release.’ 20th Biennial Meeting of Neurochemistry, Innsbruck, Austria, August 21-26, 2005;". 2005.
  47. Balosso S, Lucas SM, Bernardino L, Malva JO, Ravizza T, Ku G, Randle JCR, Allan S and Vezzani A. "‘Selective inhibition of caspase-1 reduces interleukin-1 (IL-1) beta production and release in rodent brain and protects from kainate-induced seizures.’ 26th International Epilepsy Congress, Paris, France, August 28th to September 1st, 2005, Epilepsia, vol. 46, supplement 6, pag. 202.". 2005.
  48. Bernardino L, Xapelli S, Poulsen F, Jakobsen B, Zimmer J, Duarte EP and Malva JO. "‘Effect of TNF-alpha and Interleukin-1beta in AMPA-mediated neuronal death in mouse organotypic hippocampal slice cultures.“4th Forum of European Neuroscience, Lisboa, Portugal, July 10-14. FENS Abstr. vol 2, A045.05, 2004.". 2004.
  49. Bernardino L, Xapelli S, Silva AP, Jackobsen B, Poulsen FR, Oliveira CR, Malva JO and Zimmer J. "‘Activation of microglia in excytotoxic lesions in organotypic slice cultures of the mouse hippocampus.’ 34th Annual Meeting San Diego; San Diego, October 23-27. Program No. 679.16. 2004 Abstract Viewer/Itinerary Planner.". 2004.
  50. Xapelli S, Silva AP, Bernardino L, Poulsen FR, Jakobsen B, Oliveira CR, Malva JO and Zimmer J. "‘Neuroprotection and decreased of Brain Derived Neurotrophic Factor expression mediated by neuropeptide Y2 receptor activation in mouse organotypic hippocampal slice cultures.’ 34th Annual Meeting San Diego; San Diego, October 23-27. Program No. 47.3. 2004 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2004. Online". 2004.
  51. Saavedra A, Baltazar G, Bernardino L, Carvalho C and Duarte EP. "´Upregulation of GDNF in substantia nigra postnatal cultures in response to L-DOPA and hydrogen peroxide´ 33rd Annual Meeting of Society for Neuroscience, New Orleans, E.U.A., November 8-12. Program No. 409.21. 2003 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2003. Online.". 2003.

Propriedade Intelectual

Patente
  1. Maia J, Santos T, Bernardino L, Malva JO, Ferreira L. 2011. "Non-leaching nanoparticle formulation for the intracellular delivery of hydrophobic drugs and its use to modulate cell activity and differentiation - WO2011145963".
  2. Bernardino L, Agasse F, Eiriz MF, Ferreira L, Malva JO. 2009. "Histamine released from biocompatible microparticles induce neurogenesis in the murine subventricular zone - PAT 2009/1000098".
  3. Grade S, Malva JO, Bernardino L, Agasse F. 2008. "Functional identification of SVZ-derived oligodendrocytes based on selective response to thrombin - PAT 200810008950".
  4. Agasse F, Bernardino L, Silva BA, Malva JO. 2008. "Method for the functional identification of new neurons, neural progenitors, astrocytes and immature cells from stem cell cultures and uses thereof - WO2008100168".
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023 Serra-Almeida C, Jarazo J, Cristóvão AC, Bernardino L, Schwamborn JC (2023) Human midbrain organoids carrying the SNCA triplication show autophagy impairment. ETRS & SPCE-TC Joint Meeting 2023, Coimbra, 11-13 October
2023 INVITED SPEAKER - Bernardino L (2023) MicroRNA-124-enriched small extracellular vesicles: a new therapeutic approach for Parkinson's disease. 57 Annual Meeting of the European Society for Clinical Investigation (ESCI), Prague, 7-9 June.
2023 INVITED SPEAKER - Bernardino L (2023) Neuroprotective and neurorestorative strategies for Parkinson's disease, Second IMMUPARKNET Conference, Seville, 15-17 June.
2022 Machado-Pereira M, Cristóvão AC, Ferreira L, Bernardino L, Ferreira R (2022) Retinoic acid-loaded nanoparticles protect cerebral vascular dysregulation under ischemia. International Meeting on the Brain Vasculature, online, 3 June.
2022 INVITED SPEAKER - Bernardino L (2022) MicroRNA-based therapeutic approaches for Parkinson's disease. 12th International Meeting of Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), Braga, 11-12 March.
2022 INVITED SPEAKER - Bernardino L (2022) MicroRNA-based therapeutic approaches for Parkinson's disease. Lunch Seminar. CICS-UBI, Covilhã, 5 May.
2021 INVITED SPEAKER - Bernardino L (2021) MicroRNA-124-3p-enriched Small Extracellular Vesicles as A Promising Therapeutic Approach for Parkinson's Disease. 7th NANO Boston Conference (NWC Boston 2021), Virtual, 18-20 October
2021 INVITED SPEAKER - Bernardino L (2021) MicroRNA-124-3p-enriched small extracellular vesicles as a promising therapeutic approach for Parkinson's disease. 55th Annual Scientific Meeting - ESCI Virtual 2021. Coimbra, 9-11 June.
2020 INVITED SPEAKER - Bernardino L (2020) Imaging of neural stem cells activity. ADVANCED COURSE - Advanced Imaging Methods in Neuroscience. Coimbra, 9-20 November.
2019 Serra-Almeida C, Saraiva C, Esteves M, Santos T, Ferreira R, Cristóvão AC, Bernardino L (2019) CTBPs modulation promotes neuronal and oligodendrocyte differentiation from neural stem cells in the subventricular zone. III International Congress in Health Sciences Research - Trends in Aging and Cancer, November 14-16, Covilhã.
2019 Machado-Pereira M, Pais JP, Bernardino L, Cristovão AC, Ferreira R (2019) Papel da Argonauta-2 na recuperação vascular em isquémia. 20º Congresso do Núcleo de Estudos da Doença Vascular Cerebral, Sociedade Portuguesa de Medicina Interna, Porto, 29-30 Novembro.
2019 Pais JP, Machado-Pereira M, Saraiva C, Bernardino L, Cristóvão AC, Ferreira R (2019) Argonauta-2 na resposta inflamatória pós-isquémia. 20º Congresso do Núcleo de Estudos da Doença Vascular Cerebral, Sociedade Portuguesa de Medicina Interna, Porto, 29-30 Novembro.
2019 Esteves M, Abreu R, Fernandes H, Saraiva C, Ferreira R, Cristóvão AC, Ferreira L, Bernardino L (2019) MicroRNA-124-enriched exosomes induce subventricular zone neurogenesis and counteract dopaminergic degeneration and motor deficits in a mouse model of Parkinson’s disease. III International Congress in Health Sciences Research - Trends in Aging and Cancer, November 14-16, Covilhã.
2019 Esteves M, Abreu R, Fernandes H, Saraiva C, Ferreira R, Cristóvão AC, Ferreira L, Bernardino L (2019) MicroRNA-124-enriched exosomes improve adult neurogenesis in the subventricular zone. XVI Meeting of the Portuguese Society for Neuroscience, May 30 - June 1, Lisbon.
2019 Serra-Almeida C, Saraiva C, Esteves M, Santos T, Ferreira R, Cristóvão AC, Bernardino L (2019) CTBPS: novel transcriptional regulators of neural stem cells. XIV Annual CICS-UBI Symposium, University of Beira Interior, July 4-5.
2019 Gouveia A, Fonseca C and Bernardino L (2019) De uma abordagem teórica a uma abordagem prática: transformação de sucesso de uma Unidade Curricular. 6º Congresso Nacional de Práticas Pedagógicas no ensino superior (CNaPPES). Instituto Politécnico de Santarém, July 11-12.
2018 Esteves M, Abreu R, Fernandes H, Saraiva C, Ferreira R, Cristóvão AC, Ferreira L, Bernardino L (2018) MicroRNA-enriched exosomes enhance survival and neuronal differentiation in subventricular zone cell cultures. XIII ANNUAL CICS-UBI SYMPOSIUM 2018, July 5-6, Covilhã, Portugal.
2018 Almeida C, Saraiva C, Esteves M, Santos T, Ferreira R, Cristóvão AC, Bernardino L (2018) CTBPS: Novel transcriptional regulators in neurogenesis. XIII ANNUAL CICS-UBI SYMPOSIUM 2018, July 5-6, Covilhã, Portugal.
2018 Lopes-Nunes J, Santos T, Afonso MCV, Esteves M, Saraiva C, Baltazar G, Ferreira R, Cristóvão AC, Bernardino L (2018) Neuroprotective role of CTBPs on in vitro and in vivo models for Parkinson’s disease. XIII ANNUAL CICS-UBI SYMPOSIUM 2018, July 5-6, Covilhã, Portugal.
2018 Fiadeiro M, Sousa AC, Afonso M, Sharma M, Bernardino L, Freire M, Cristóvão AC (2018) New antioxidant formulation to prevent neuronal degeneration in Parkinson’s disease. XIII ANNUAL CICS-UBI SYMPOSIUM 2018, July 5-6, Covilhã, Portugal.
2017 Almeida C, Saraiva C, Santos T, Esteves M, Bernardino L (2017) CtBPs: novel transcriptional regulators in neurogenesis. XLVIII Reunião da Sociedade Portuguesa de Farmacologia, Annual meeting of The Portuguese Pharmacological Society, Faculty of Medicine, University of Lisboa, February 5-7.
2017 Ferreira R, Machado-Pereira M, Fonseca M, Santos T, Sargento-Freiras J, Tjeng R, Paiva F, Castelo-Branco M, Ferreira L, Bernardino L (2017) Retinoic acid-loaded polymeric nanoparticles modulate the endothelial and microglial response under ischemia. Annual meeting of The Portuguese Pharmacological Society, Faculty of Medicine, University of Lisboa, February 5-7.
2017 Sousa ACA, Afonso MCV, Bernardino L, Neves CMSS, Sharma M, Freire MG, Cristóvão AC (2017) New antioxidant ionic liquid chemical formulations to prevent neuronal degeneration in Parkinson’s disease. Annual meeting of The Portuguese Pharmacological Society, Faculty of Medicine, University of Lisboa, February 5-7.
2017 Esteves M, Abreu R, Fernandes H, Ferreira L, Bernardino L (2017) MICRORNAS-enriched exosomes enhance survival and neuronal differentiation in subventricular zone (SVZ) cell cultures. Annual meeting of The Portuguese Pharmacological Society, Faculty of Medicine, University of Lisboa, February 5-7.
2017 Saraiva C, Talhada D, Rai A, Ferreira R, Ferreira L, Bernardino L, Ruscher K. (2017) Potential therapeutic effect of microRNA-124-loaded nanoparticles in ischemic stroke. Annual meeting of The Portuguese Pharmacological Society, Faculty of Medicine, University of Lisboa, February 5-7.
2017 INVITED SPEAKER - Bernardino L (2017) Nanomedicine approaches to modulate neural stem cells for brain repair. XV Portuguese Society for Neuroscience meeting, Braga, May 26th.
2017 INVITED SPEAKER - Bernardino L (2017) MicroRNAs in neurogenesis: basic concepts and future prospects for brain repair therapies. CNC-IBILI Seminars, Biocant, Cantanhede, May 3rd.
2016 Fonseca B, Rodrigues M, Cristovão AC, Fortuna A, Bernardino L, Falcão A, Alves G (2016) HPLC-FLD method for the simultaneous determination of cathecolamines and related-compounds in the rat brain tissue. "XLVI Annual meeting of The Portuguese Pharmacological Society", Porto, February 4-6.
2016 INVITED SPEAKER - Bernardino L (2016) Nanomedicine approaches to modulate neural stem cells in brain repair, Life Sciences PhD Days 2016, University of Luxembourg, November 24-25.
2015 Ferreira R, Fonseca MC, Santos T, Sargento-Freitas J, Tjeng R, Paiva F, Ferreira L, Bernardino L (2015) Modulação vascular da sobrevivência e diferenciação de células estaminais neurais, induzida por nanopartículas poliméricas com ácido retinóico, após isquémia. 9th Portuguese Stroke society meeting, Porto, February 5-7.
2015 Machado-Pereira M, Santos T, Bernardino L, Ferreira R (2015) Efeito anti-inflamatório de nanopartículas poliméricas com ácido retinóico encapsulado num contexto isquémico. 9th Portuguese Stroke society meeting, Porto, February 5-7.
2015 Saraiva CM, Paiva J, Santos T, Ferreira L, Bernardino L (2015) MicroRNA-loaded nanoparticles induce subventricular zone neurogenesis in a mouse model for Parkinson’s disease. "9th Annual meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)”, Carcavelos, October 15-16.
2015 Santos T, Boto C, Ferreira R, Ferreira L, Bernardino L (2015) Light-Sensitive Retinoic Acid-Loaded Nanoparticles Modulate Murine Subventricular Neurogenesis. "XLV Annual meeting of The Portuguese Pharmacological Society", February 5-6, FCM-NOVA, Lisboa.
2015 Saraiva CM, Paiva JM, Ferreira L, Bernardino L (2015) Modulation of Neural Stem Cells from the Subventricular Zone by microRNA-loaded Nanoparticle. "XLV Annual meeting of The Portuguese Pharmacological Society", February 5-6, FCM-NOVA, Lisboa.
2015 Ferreira R, Fonseca MC, Santos T, Ferreira LS, Bernardino L (2015) Therapeutic application of retinoic acid-loaded nanoparticles for neurovascular repair in a murine in vitro model of ischemia. "XLV Annual meeting of The Portuguese Pharmacological Society", February 5-6, FCM-NOVA, Lisboa.
2015 Lindeza P, Ferreira R, Santos T, Saraiva C, Bernardino L, Cristóvão AC (2015) Characterization of HMGB1 and RAGE protein levels in experimental models of Parkinson’s disease. “X Annual CICS Symposium”; University of Beira Interior, Covilhã, July 6-7.
2015 Santos T, Boto C, Ferreira R, Saraiva C, Bragança J, Cristóvão AC, Ferreira L, Bernardino L (2015) Light-sensitive retinoic acid-loaded nanoparticles induce subventricular neurogenesis. “X Annual CICS Symposium”; University of Beira Interior, Covilhã, July 6-7.
2015 Saraiva CM, Paiva J, Santos T, Ferreira L, Bernardino L (2015) MicroRNA-loaded nanoparticles as modulators of neurogenesis in the subventricular zone. “X Annual CICS Symposium”; University of Beira Interior, Covilhã, July 6-7.
2015 INVITED SPEAKER - Bernardino L (2015) Neural stem cells and nanotechnology in brain repair therapies. I Congress in Health Sciences Research: Towards Innovation and Entrepreneurship, Trends in Endocrinology and Neurosciences, UBI, November 26-28.
2015 INVITED SPEAKER - Bernardino L (2015) O potencial das células estaminais neurais na medicina regenerativa. X Congresso Científico AEFFUP Neurociência: Um olhar através do cérebro, ICBAS/FFUP, Porto, November 19-20.
2015 INVITED SPEAKER - Bernardino L (2015) Nanomedicina para a recuperação neurovascular do acidente vascular cerebral , Encontros com a Inovação em Saúde organizado pelo Health Cluster Portugal (HCP) Translational and clinical research: from bench to bedside, from Portugal to the world, April 16th, Coimbra.
2015 INVITED SPEAKER - Bernardino L (2015) Histamine modulates dopaminergic neuronal survival by boosting microglial activity, European Histamine Research Society, 44st Annual Meeting, May 6-9, Malaga, Spain.
2014 Saraiva CM, Paiva JM, Ferreira L, Bernardino L. MicroRNA-124 loaded nanoparticles modulate neurogenesis in the subventricular zone. Program No. 199.12. 2014 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.
2014 Santos T, Ferreira R, Maia J, Agasse F, Xapelli S, Cortes L, Bragança J, Malva J O, Ferreira L, Bernardino L (2014) Therapeutic Potential of Retinoic Acid-Loaded Nanoparticles for Brain Repair. "XLIV Annual meeting of The Portuguese Pharmacological Society", Coimbra, February 5-7.
2014 Saraiva CM, Paiva J M, Ferreira L, Bernardino L (2014) MicroRNA-124 loaded nanoparticles modulate neurogenesis in the subventricular zone. "XLIV Annual meeting of The Portuguese Pharmacological Society", Coimbra, February 5-7.
2014 Ferreira R, Santos T, Amar A, Tahara S M, Chen T C, Giannotta S L, Hofman F M, Bernardino L (2014) MicroRNA-18a Improves Human Cerebral Arteriovenous Malformation Endothelial Cell Function. "XLIV Annual meeting of The Portuguese Pharmacological Society", Coimbra, February 5-7.
2014 Saraiva C, Paiva J, Ferreira L, Bernardino L (2014) Subventricular zone’s neurogenesis is modulated by MicroRNA-124 loaded nanoparticles. “IX Annual CICS Symposium”; University of Beira Interior, Covilhã, June 30th- July 1st.
2014 Santos T, Ferreira R, Maia J, Agasse F, Xapelli S, Cortes L, Bragança J, Malva JO, Ferreira L, Bernardino L (2014) Retinoic Acid-Loaded Nanoparticles for Brain Repair. “IX Annual CICS Symposium”; University of Beira Interior, Covilhã, June 30th- July 1st. 2014.
2014 INVITED SPEAKER - Bernardino L (2014) The role of inflammation in brain repair: focus on neurogenesis. Workshop Profiling alterations in microglia dynamic properties by neuroinflammation; Faculty of Pharmacy, University of Lisbon, November 7th.
2014 INVITED SPEAKER - Bernardino L (2014) "Células estaminais na reparação cerebral". Sessão Clínica no Centro Hospitalar Cova da Beira (CHCB), Dia Nacional do doente com AVC, March 27th.
2014 INVITED SPEAKER - Bernardino L (2014) "Células estaminais na reparação cerebral". Jornadas Tecnológicas da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa, Jortec BCM 2014; Universidade Nova de Lisboa, February 14th.
2013 Xapelli S, Agasse F, Ribeiro FF, Bernardino L, Schitine CS, Heimann A., Ferro ES, De Melo Reis RA, Sebastião AM, Malva JO (2013) Hemopressin stimulates oligodendrogenesis in neural stem cell cultures from the subventricular zone – XIII Annual meeting of The Portuguese Society for Neuroscience, Luso (Portugal), May 30, 31 and June 1.
2013 Ferreiro E, Valero J, Bernardino L, Pereira C, Agasse F. (2013) Imbalance in the stem/progenitor cells properties leads to the suppression of neurogenesis in the triple transgenic mouse model of Alzheimer’s disease. XIII Annual meeting of The Portuguese Society for Neuroscience, Luso (Portugal), May 30, 31 and June 1.
2013 Esteves M, Saraiva T, Rocha S, Baltazar G, Ferreira L, Bernardino L. (2013) Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model of Parkinson’s disease. XIII Annual meeting of The Portuguese Society for Neuroscience, Luso (Portugal), May 30, 31 and June 1.
2013 Saraiva T, Rocha S, Esteves M, Cristóvão AC, Baltazar G, Alves G, Bernardino L. (2013) Histamine modulates dopaminergic neuronal survival by boosting microglial activity. XIII Annual meeting of The Portuguese Society for Neuroscience, Luso (Portugal), May 30, 31 and June 1.
2013 Ferreiro E, Valero J, Bernardino L, Pereira C, Agasse F. (2013) Imbalance in the stem/progenitor cells properties leads to the suppression of neurogenesis in the triple transgenic mouse model of Alzheimer’s disease. XIII Annual meeting of The Portuguese Society for Neuroscience, Luso (Portugal), May 30, 31 and June 1.
2013 Xapelli S, Agasse F, Ribeiro FF, Bernardino L, Schitine CS, Heimann A., Ferro ES, De Melo Reis RA, Sebastião AM, Malva JO (2013) Hemopressin stimulates oligodendrogenesis in neural stem cell cultures from the subventricular zone – XIII Annual meeting of The Portuguese Society for Neuroscience, Luso (Portugal), May 30, 31 and June 1.
2013 INVITED SPEAKER - Bernardino L (2013) Células Estaminais na Reparação Cerebral. I Ciclo de Conferências Biomédicas à Tarde; UBI-Covilhã, April 9th.
2012 Xapelli S, Sardà L, Bernardino L, Santos T, Schitine C, Agasse F, Malva JO (2012) (R)-(+)-Methanandamide stimulates neurogenesis in neural stem cell cultures from the subventricular zone - “XLII Annual meeting of The Portuguese Pharmacological Society”, Lisbon (Portugal), February 1-3.
2012 Santos T, Ferreira R, Maia J, Xapelli S, Cortes L, Agasse F, Bragança J, Ferreira L, Malva JO, Bernardino L (2011) Intracellular Delivery of Retinoic Acid-Loaded Nanoparticles Modulates Neuronal Differentiation of Stem cells. “6th Annual meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)”, Biocant-Cantanhede, April 28-29. Prize for the best oral communication
2011 Ferreiro E, Valero J, Bernardino L, Pereira C, Agasse F (2011) Impaired properties of stem/progenitor cells contribute to decreased neurogenesis in the triple transgenic mouse model of Alzheimer’s disease. “25ª Reunião do Grupo de Estudo de Envelhecimento Cerebral e Demências”, Hotel dos Templários, Tomar, June 03-04.
2011 INVITED SPEAKER - Bernardino L (2011) As células estaminais na reparação do cérebro doente: ficção ou realidade? Ciclo de Conferências Smile Togheter; Universidade Católica Portuguesa; Viseu; February 18th.
2010 Santos T, Maia J, Aday S, Bernardino L, Malva JO, Ferreira L (2010) Nanomaterials to drive the differentiation of stem cells into neuronal cells. “5th Annual meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)”, Caldas das Taipas, Guimarães, Portugal, May 20-21.
2010 Eiriz MF, Bernardino L, Xapelli S, Grade S, Rosa A, Cortes L, Agasse F, Ferreira L, Malva JO (2010) Histamine releasing PLGA microparticles as a new way to drive brain repair. “5th Annual meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)”, Caldas das Taipas, Guimarães, Portugal, May 20-21. Prize for the best oral communication
2010 INVITED SPEAKER - Bernardino L, Eiriz MF, Xapelli S, Grade S, Rosa A, Cortes L, Agasse F, Ferreira F and Malva JO (2010) Histamine is a Proneurogenic Factor on Subventricular Zone Stem/Progenitor Cells: A New Approach for Brain Repair Therapies. ENI-Net meeting, Coimbra, May 6-8.
2009 Baptista S, Bento AR, Bernardino L, Ribeiro CF, Malva JO, Agasse F, Silva AP (2009) Neuropeptide Y prevents methamphetamine-induced cell death in Dentate Gyrus cell cultures. “XL Anual meeting of the Portuguese Society for Pharmacology”, Porto, December 2-4.
2009 Bernardino L, Eiriz MF, Xapelli S, Grade S, Rosa A, Cortes L, Agasse F, Ferreira F and Malva JO (2009) Histamine released from biocompatible microparticles induce neuronal differentiation in the subventricular zone. “XL Anual meeting of the Portuguese Society for Pharmacology”, Porto, December 2-4.
2009 Grade S, Agasse F, Bernardino L, Gomes C, Malva JO (2009) Functional identification of SVZ-derived oligodendrocytes based on selective response to thrombin. “4th Annual meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)”, Lisboa, April 29-30.
2009 Bernardino L, Agasse F, Xapelli S, Grade S, Rosa A, Malva JO (2009) Histamine promotes neuronal differentiation from subventricular zone (SVZ) cell cultures. “4th Annual meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)”, Lisboa, April 29-30.
2009 INVITED SPEAKER - Bernardino L (2009) The dual role of neuroinflammation in excitotoxicity and neurogenesis. 1st Portuguese-Spanish Mini-Symposium on Glia Cell Biology, Braga, June 4th.
2009 INVITED SPEAKER - Bernardino L (2009) "As células estaminais neurais na reparação cerebral". Encontro Nacional dos Estudantes de Bioquímica (ENEBIOQ), Covilhã, November 28th.
2008 Agasse F, Bernardino L, Silva B, Grade S, Malva JO. (2008) Single Cell Calcium Imaging and pharmacology of neurogenesis: a method useful for drug screening in Neural Stem Cell Cultures. 3rd Annual meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), Faro, Portugal, April 23-24.
2008 Bernardino L, Agasse F, Silva B, Ferreira R, Grade S, Malva JO. (2008) Neurogenesis in the Subventricular Zone: Tumor Necrosis Factor-alpha as a key modulator. 3rd Annual meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), Faro, Portugal, April 23-24.
2008 Agasse F, Bernardino L, Kristiansen H, Christiansen S, Ferreira R, Silva B, Grade S, Woldbye D, Malva JO. Subventricular zone cells as tool for brain repair. FENS Abstr., vol. 4, 232.1, 2008.
2007 Agasse F, Bernardino L, Ferreira R, Grade S, Silva BA, Malva JO. (2007) NPY promotes neurogenesis in Subventricular Zone Cell (SVZ) cell cultures. 2nd Annual meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), Coimbra, Portugal, April 27-28.
2007 Bernardino L, Agasse F, Grade S, Ferreira R, Silva BA, Malva JO. (2007) Tumor Necrosis Factor-Alpha modulates cell proliferation, survival and differentiation of new neurons in SVZ cell cultures. 2nd Annual meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), Coimbra, Portugal, April 27-28.
2007 Bernardino L, Agasse F, Grade S, Ferreira R, Silva BA, Malva JO. (2007) Tumor Necrosis Factor-alpha triggers differentiation of new neurons in neonatal neural stem cells. 10th Anual meeting of the Portuguese Society for Neuroscience (SPN), Ofir, Portugal, May 23-26.
2007 Malva JO, Silva AP, Xapelli S, Ferreira R, Bernardino L, Agasse F. (2007) Neuropeptide Y in neuroprotection and neurogenesis- tool for brain repair? 1º Colóquio Português-Brasileiro em Neuroquímica, Ofir, Portugal, May 23th.
2006 Xapelli S, Bernardino L, Silva AP, Cavadas C, Grouzmann E, Poulsen F, Jakobsen B, Oliveira CR, Zimmer J, Malva JO. (2006) Neuroprotection by NPY and BDNF against excitotoxicity in mouse hippocampal slice cultures. XXXVII Anual meeting of the Portuguese Society for Pharmacology, Porto, December 5-7.
2006 Bernardino L, Agasse F, Grade S, Ferreira R, Silva BA, Malva JO. (2006) Tumor necrosis factor-alpha induces neurogenesis in subventricular zone cell cultures. XXXVII Anual meeting of the Portuguese Society for Pharmacology, Porto, December 5-7.
2006 Agasse F, Bernardino L, Grade S, Silva BA, Malva JO (2006) Differentiation of subventricular zone (SVZ) cells following treatment with cytokines: a calcium imaging study. 1st Annual meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), Funchal, Madeira, May 30-31.
2006 Bernardino L, Agasse F, Grade S, Silva BA, Malva JO. (2006) TNF-alpha induces neuronal differentiation in subventricular zone cell cultures of the mouse brain. 1st Annual meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), Funchal, Madeira, May 30-31.
2005 Xapelli S, Bernardino L, Silva AP, Cavadas C, Grouzmann E, Poulsen FR, Jakobsen B, Zimmer J and Malva JO. (2005) Neuroprotection mediated by neuropeptide Y2 receptor activation in mouse hippocampal organotypic cultures: cross-talk with BDNF. 9th Meeting of the Portuguese Society for Neurosciences, Luso, Portugal, May 19-20, 2005. Published in ‘Sinapse’, Vol 5, nº1, pag 96, May 2005.
2005 Bernardino L, Xapelli S, Silva AP, Poulsen FR, Jakobsen B, Vezzani A, Malva JO and Zimmer J. (2005) Neuroprotective and neurotoxic effects mediated by activation of distinct Tumor Necrosis Factor (TNF)-alpha receptor subtypes in mouse organotypic hippocampal slice cultures. 9th Meeting of the Portuguese Society for Neurosciences, Luso, May 19-20, 2005. Published in ‘Sinapse’, Vol 5, nº1, YL1, pag 96, May 2005; Selected as a Young Speaker
2005 Bernardino L., Role of Inflammation in neurodegeneration and neuroprotection. 3rd Meeting of the Center for Neuroscience and Cell Biology, Bencanta, September 23, 2005.
2005 Bernardino L, Balosso S, Ravizza T, Xapelli S, Ku G, Randle JC, Zimmer J, Malva JO, and Vezzani A. (2005) Activation of P2X7 receptors causes microglia-like cell apoptosis and contributes to increased susceptibility of pyramidal cells to AMPA-induced excitotoxicity. XXXVI Annual meeting of the Portuguese Pharmacological Society, Lisbon, December 5-7.
2004 Xapelli S, Silva AP, Bernardino L, Jakobsen B, Zimmer J, Oliveira CR and Malva JO. (2004) Neuroprotection by Neuropeptide Y receptor activation in excitotoxicity and epilepsy, 4th Forum of European Neuroscience, Symposium “Brain damage and Repair”, Lisboa, July 10-14.
2004 Silva AP, Xapelli S, Pinheiro PS, Bernardino L, Carvalho AP, Carvalho CM, Oliveira CR, Jakobsen B, Zimmer J and Malva JO. (2004) Neuroprotection mediated by neuropeptide Y receptors in the hippocampus, XIV Annual meeting of the Portuguese Biochemical Society, Vilamoura, Portugal, December 2-4.

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2023/09/05 - Atual Potencial terapêutico de células estaminais no AVC.
Orientador
Medicine (Mestrado)
Universidade da Beira Interior, Portugal
2022/12 - Atual Fellowship from the Foundation for Science and Technology (Reference: 2022.13027.BD) PhD in Biomedicine, University of Beira Interior. Thesis title: New role for histamine: protecting the depressed brain.
Orientador
Universidade da Beira Interior, Portugal
2019/12 - Atual Fellowship from the Foundation for Science and Technology (Reference: SFRH/BD/149036/2019) PhD in Biomedicine, University of Beira Interior. Thesis title: The interplay between microRNAs and alpha-synuclein: exploring novel therapeutic approaches for Parkinson's disease.
Orientador de Ana Catarina Almeida
Universidade da Beira Interior, Portugal
2019/04 - Atual Marie Curie fellowship from the Marie Sklodowska-Curie Innovative Training Networks-ITN, European Union’s Horizon 2020 research and innovation programme (Grant agreement nº 764958) Thesis title: Engineered formulations for brain gene edition.
Coorientador de Angela Maria Barrera Sandoval
Universidade de Coimbra, Portugal
2018/09 - Atual MSc in Biomedical Sciences, University of Beira Interior. Thesis title: Development of novel steroids for the treatment of neurodegenerative diseases.
Orientador de Mariana Filipa dos Santos Marques
Universidade da Beira Interior, Portugal
2024/04/15 - 2024/07/16 Intranasal delivery of Bromocriptine-loaded Ceria Nanoparticles: A potential new therapeutic approach for Parkinson's disease. Fellowship from EMBO Scientific Exchange Grant, European Molecular Biology Organization (EMBO)
Orientador
EMBO Scientific Exchange Grant, European Molecular Biology Organization (EMBO) (Doutoramento)
Universidade da Beira Interior, Portugal
2022/09 - 2023/11 MSc in Biomedical Sciences, University of Beira Interior.Thesis entitled: Desenvolvimento de Um Modelo Ex Vivo de Envelhecimento em Culturas Organotípicas de Hipocampo.
Orientador
Universidade da Beira Interior, Portugal
2022/09 - 2023/11 MSc in Biochemistry, University of Beira Interior. Thesis entitled: Evaluation of the Role of C-Terminal Binding Proteins (CTBP) in the Neuroimmune Response.
Orientador
Universidade da Beira Interior, Portugal
2021/09/02 - 2023/02 MSc in Biomedical Sciences, University of Beira Interior. Thesis title: Genetic regulation in Parkinson's disease: microRNAs as therapeutic targets
Orientador
Universidade da Beira Interior, Portugal
2019/05 - 2023 PhD in Biomedicine, University of Beira Interior. Thesis title: SalivaPrint as a tool for non-invasive diagnosis.
Coorientador de Eduardo Jorge Mónica Esteves
Universidade da Beira Interior, Portugal
2017/04 - 2023 Fellowship from the Foundation for Science and Technology (Reference: SFRH/BD/121822/2016) PhD in Biomedicine, University of Beira Interior. Thesis title: MicroRNAs-enriched exosomes as a new therapy for brain repair in stroke.
Orientador de Marta Raquel Carrola Esteves
Universidade da Beira Interior, Portugal
2021/09/02 - 2022/11 MSc in Biomedical Sciences, University of Beira Interior. Thesis title: Role of microRNAs on glial activity in a Parkinson’s disease mouse model.
Orientador
Universidade da Beira Interior, Portugal
2020/09/05 - 2022/03/31 MSc in Pharmaceutical Sciences, University of Beira Interior. Thesis title: Processo de senescência celular do envelhecimento biológico: as estratégias senolíticas em fase de ensaios clínicos
Orientador
Universidade da Beira Interior, Portugal
2020 - 2021 MSc in Biomedical Sciences, University of Beira Interior. Thesis title: "The impact of peripheric inflammation in the susceptibility for neurodegenerative diseases"
Orientador
Universidade da Beira Interior, Portugal
2019 - 2020 MSc in Pharmaceutics Science, University of Beira Interior. Thesis title: "Relação entre a doença de Parkinson e as doenças inflamatórias gastrointestinais: Experiência profissionalizante na vertente de investigação, Fármacia hospitalar e comunitária"
Orientador
Universidade da Beira Interior, Portugal
2019/03 - 2019/12 Project title: Interdisciplinary Challenges On Neurodegeneration. Funding: Integrated programmes for SR&TD-Scientific Research & Technological Development. CENTRO-01-0145-FEDER-000013.
Orientador de Ana Catarina Almeida
Universidade da Beira Interior, Portugal
2018/10 - 2019/05 Post-Doctoral Fellow in the setting of the project Interdisciplinary Challenges On Neurodegeneration. Integrated programmes for SR&TD-Scientific Research & Technological Development. CENTRO-01-0145-FEDER-000013.
Orientador de Cláudia Marisa Monteiro Saraiva
Universidade da Beira Interior, Portugal
2017/09 - 2018/08 Post-Doctoral Fellow in the setting of the project Interdisciplinary Challenges On Neurodegeneration. Integrated programmes for SR&TD-Scientific Research & Technological Development. CENTRO-01-0145-FEDER-000013.
Orientador de Ana Clara Braz Cristóvão
Universidade da Beira Interior, Portugal
2017/09 - 2018/07 MSc in Biomedical Sciences, University of Beira Interior. Thesis title: Evaluation of the neurogenic response evoked by activation of the G protein-coupled estradiol receptor
Coorientador de Catarina Inês Duarte Chendo
Universidade da Beira Interior, Portugal
2017/09 - 2018/07 MSc in Biomedical Sciences, University of Beira Interior. Thesis title: The role of novel transcriptional regulation mechanisms in neurogenesis.
Orientador de Ana Catarina Almeida
Universidade da Beira Interior, Portugal
2017/09 - 2018/07 MSc in Biomedical Sciences, University of Beira Interior. Thesis title: Novel transcriptional regulation mechanisms associated with Parkinson’s disease pathogenesis: from biological activity towards therapy.
Orientador de Jéssica Lopes Nunes
Universidade da Beira Interior, Portugal
2012/09 - 2017/12 Fellowship from the Foundation for Science and Technology (Reference: SFRH/BD/90365/2012) PhD in Bioengineering Systems, MIT Portugal PhD Program, Universidade Nova de Lisboa Thesis title: MicroRNA-124-loaded nanoparticles as a new promising therapeutic tool for neural stem cell-based brain repair strategies.
Orientador de Cláudia Marisa Monteiro Saraiva
Universidade Nova de Lisboa, Portugal
2014/04 - 2016/12 Post-Doctoral Fellowship from the Foundation for Science and Technology (Reference: SFRH/BPD/94228/2013) Project title: Therapeutic application of retinoic acid-loaded nanoparticles for neurological and vascular repair in stroke.
Orientador de Raquel Margarida da Silva Ferreira
Universidade da Beira Interior, Portugal
2015/09 - 2016/11 MSc in Biomedical Sciences, University of Beira Interior. Thesis title: Unveiling a novel crosstalk between histamine and lipopolysaccharide in the modulation of hippocampal inflammation and neurogenesis.
Orientador de Sandra Barata Antunes
Universidade da Beira Interior, Portugal
2015/09 - 2016/06 MSc in Biomedical Sciences, University of Beira Interior. Thesis title: Therapeutic application of endothelial cells treated with nanoparticles containing retinoic acid in an experimental model of stroke.
Coorientador de Marta Sofia Machado Pereira
Universidade da Beira Interior, Portugal
2012/01 - 2016/03 Fellowship from the Foundation for Science and Technology (Reference: SFRH/BD/79526/2011) PhD in Biosciences, speciality in Neurosciences, University of Coimbra. Thesis title: Therapeutic potential of retinoic acid-loaded nanoparticles for brain repair.
Orientador de Tiago Alexandre Ramos Teixeira de Sousa Santos
Universidade de Coimbra, Portugal
2014/09 - 2015/07 MSc in Biomedical Sciences, University of Beira Interior. Thesis title: Evaluation of dopaminergic degeneration influence on endothelial activity in experimental models of Parkinson's disease.
Coorientador de Patrícia Vanessa Almeida Lindeza
Universidade da Beira Interior, Portugal
2014/09 - 2015/07 MSc in Biotechnology, University of Beira Interior. Thesis title: Therapeutic application of retinoic acid-loaded nanoparticles for neurological and vascular repair in stroke.
Coorientador de Márcia Carvalho da Fonseca
Universidade da Beira Interior, Portugal
2009/09 - 2013/12 Fellowship from the Foundation for Science and Technology (Reference: SRRH/BD/42848/2008) PhD in Bioengineering Systems, MIT Portugal PhD Program, Universidade Nova de Lisboa Thesis title: Neurogenesis in the hippocampus: histamine and AMPA receptors facilitate differentiation and synaptic integration of new neurons.
Coorientador de Maria Francisca Santos Eiriz
Universidade Nova de Lisboa, Portugal
2012/09 - 2013/11 MSc in Biochemistry, University of Beira Interior. Thesis title: Histamine modulates dopaminergic neuronal survival by boosting microglial activity.
Orientador de Tatiana Filipa Melo Saraiva
Universidade da Beira Interior, Portugal
2012/09 - 2013/07 MSc in Biotechnology, University of Beira Interior. Thesis title: Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model of Parkinson’s disease.
Orientador de Marta Raquel Carrola Esteves
Universidade da Beira Interior, Portugal
2012/04 - 2012/09 Project title: Histamine versus antihistamines: new modulators of neurogenesis? (Reference: PTDC/SAU-NEU/104415/2008)
Orientador de Sandra Catarina Moreira Rocha
Universidade da Beira Interior, Portugal
2011/08 - 2012/07 MSc in Biochemistry, University of Beira Interior. Thesis title: Histamine modulates nitric oxide release by microglia and dopaminergic neuronal survival
Orientador de Joel Pereira Pires
Universidade da Beira Interior, Portugal
2011/02 - 2012/02 Project title: Histamine versus antihistamines: new modulators of neurogenesis? (Reference: PTDC/SAU-NEU/104415/2008)
Orientador de Raquel Margarida da Silva Ferreira
Universidade de Coimbra, Portugal
2010/10 - 2011/12 Project title: Histamine versus antihistamines: new modulators of neurogenesis? (Reference: PTDC/SAU-NEU/104415/2008)
Orientador de Tiago Alexandre Ramos Teixeira de Sousa Santos
Universidade de Coimbra, Portugal
2009/09 - 2010/07 MSc in Cell Biology, University of Coimbra. Thesis title: Methamphetamine-induced microglial cells toxicity: the role of TNF-alpha.
Coorientador de Sandrine Pontes Machado
Universidade de Coimbra, Portugal
2009/09 - 2010/07 MSc in Cell Biology, University of Coimbra. Thesis title: Differentiation of neural stem cells by a novel retinoic acid-loaded nanoparticles delivery system.
Orientador de Tiago Alexandre Ramos Teixeira de Sousa Santos
Universidade de Coimbra, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2024/06/06 - 2024/06/08 Summer School COST Models for Parkinson's disease: from basics to translation. COST CA21117 - The role of IMMUnity in tackling PARKinson's disease through a Translational NETwork (IMMUPARKNET) (2024/06/06 - 2024/06/08)
Conferência (Presidente da Comissão Organizadora)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2023/10/11 - 2023/10/13 ETRS & SPCE-TC 2023 Joint Annual Meeting (2023/10/11 - 2023/10/13)
Congresso (Membro da Comissão Científica)
Universidade de Coimbra, Portugal
2022/07/20 - 2022/07/21 XVII International CICS-UBI Symposium (2022/07/20 - 2022/07/21)
Encontro (Membro da Comissão Científica)
2022/06/03 - 2022/06/03 International Meeting on the Brain Vasculature (2022/06/03 - 2022/06/03)
Conferência (Membro da Comissão Organizadora)
2022/03/11 - 2022/03/12 12th International Meeting of Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC) (2022/03/11 - 2022/03/12)
Congresso (Membro da Comissão Científica)
2019 - 2019 III International Congress in Health Sciences Research - Trends in Aging and Cancer, Covilhã, 14-16 November, 2019 (2019 - 2019)
Congresso (Membro da Comissão Científica)
2019 - 2019 XVI Meeting of the Portuguese Society for Neuroscience (SPN), Lisboa, May 30- June 1, 2019 (2019 - 2019)
Congresso (Membro da Comissão Científica)
2019 - 2019 11th International Meeting of Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), Lisboa, October 10-12, 2019. (2019 - 2019)
Congresso (Membro da Comissão Científica)
2018 - 2018 International advanced course “Translational approaches for regenerative-based therapies.”, Faculty of Health Sciences, University of Beira Interior, November 29-30, 2018. (2018 - 2018)
Congresso (Presidente da Comissão Organizadora)
Universidade da Beira Interior, Portugal
2018 - 2018 Practical course on calcium imaging, Faculty of Health Sciences, University of Beira Interior, November 22-23, 2018. (2018 - 2018)
Conferência (Coorganizador)
Universidade da Beira Interior, Portugal
2017 - 2017 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), University of Beira Interior, Covilhã, October 12-14, 2017. (2017 - 2017)
Congresso (Presidente da Comissão Organizadora)
Universidade da Beira Interior, Portugal
2016 - 2016 XI Annual CICS-UBI Symposium, Universidade da Beira Interior, Covilhã, June 30 July 1, 2016. (2016 - 2016)
Congresso (Membro da Comissão Científica)
2015 - 2015 X Annual CICS-UBI Symposium, Universidade da Beira Interior, Covilhã, July 6-7, 2015. (2015 - 2015)
Congresso (Membro da Comissão Científica)
2015 - 2015 I Congress in Health Sciences Research: Towards Innovation and Entrepreneurship, Trends in Endocrinology and Neurosciences, Universidade da Beira Interior, Covilhã, November 26-28, 2015. (2015 - 2015)
Congresso (Membro da Comissão Científica)
2015 - 2015 X Scientific Congress AEFFUP “Neurociência: Um olhar através do cérebro”, ICBAS/FFUP, Porto, November 19-20, 2015. (2015 - 2015)
Conferência (Membro da Comissão Científica)
2013 - 2013 1st Advanced Course on Fluorescence Microscopy and Image Analysis", University of Beira Interior, Covilhã, November 22-24, 2013. (2013 - 2013)
Congresso (Presidente da Comissão Organizadora)
Universidade da Beira Interior, Portugal
2013 - 2013 XIII Meeting of the Portuguese Society for Neuroscience, Luso, May 30th–June 1st, 2013 (2013 - 2013)
Congresso (Membro da Comissão Organizadora)
2013 - 2013 I International Meeting on Stem Cells for Regenerative Medicine and Drug Screening”, Biocant, July 19th, 2013 (2013 - 2013)
Congresso (Membro da Comissão Organizadora)
2011 - 2011 6th International meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)”, Biocant-Cantanhede, April 28-29, 2011. (2011 - 2011)
Congresso (Membro da Comissão Organizadora)
2004 - 2004 7th International NPY Meeting”, Hotel Meliá Confort, Coimbra, February 3-7, 2004. (2004 - 2004)
Congresso (Membro da Comissão Organizadora)

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2023 Thesis entitled: Expression of the transferrin receptor and permeability of the blood brain barrier in ischemic stroke, University of Coimbra, July 20.
Arguente principal
Sara Bernardo Castro (Doutoramento)
2023 Thesis entitled: MicroRNAs-enriched exosomes as a new therapy for Parkinson’ disease, University of Beira Interior, July 5.
Vogal
Marta Raquel Carrola Esteves (Doutoramento)
2023 Thesis entitled: Otimização e Implementação de Um Método de Preparação de Fibrilas de Alfa-Sinucleína para Posterior Desenvolvimento de Um Modelo Animal da Doença de Parkinson. University of Beira Interior, July 18.
Arguente principal
Joana Sofia Ribeiro Saraiva (Mestrado)
2023 Thesis entitled: Evaluation of the Role of C-Terminal Binding Proteins (CTBP) in the Neuroimmune Response, University of Beira Interior, November 17.
Vogal
Mariana Massano (Mestrado)
2023 Thesis entitled: Compósitos Biocerâmicos de ß-Tcp Reforçados com Zircónia. Fabrico e Caracterização Física, Mecânica, Microestrutural e Biológica, University of Beira Interior, November 2.
Presidente do júri
Vanessa Sofia Cordeiro Mão de Ferro (Mestrado)
2023 Thesis entitled: Blackberries and Mulberries from Covilhã as Health Promotors: Physical and Phytochemical Characterization and Biological Potential, University of Beira Interior, November 2.
Presidente do júri
Mariana Sofia Morgado Martins (Mestrado)
2023 Thesis entitled: Impact of the Endocrine Disruptor Methoxychlor on the Survival and Glycolytic Metabolism of Sertoli Cells, University of Beira Interior, October 30.
Presidente do júri
Mariana Costa Bordadágua (Mestrado)
2023 Thesis entitled: : Desenvolvimento de Um Modelo Ex Vivo de Envelhecimento em Culturas Organotípicas de Hipocampo, University of Beira Interior, November 3.
Vogal
Luiza Maria Ferreira Lopes Athayde (Mestrado)
2023 Thesis entitled: Estudo do Efeito das Citocinas Pró- Inflamatórias IFN-g e IL-17a na Ativação de Linfócitos T Humanos Mediada Pela IL-15, University of Beira Interior, November 2.
Presidente do júri
Leila Regina Homem Duarte (Mestrado)
2023 Thesis entitled: Relatório de Estágio Colheita em Zaragatoa É Suficiente para Deteção de Bactérias?, University of Beira Interior, November 3.
Presidente do júri
Joana Rita Protásio Valério (Mestrado)
2023 Thesis entitled: Study of the Effect of the Anti-Inflammatory Cytokines Il-10 and Tgf-ß on the Il-15- Induced Activation of Human T Cells, University of Beira Interior, November 2.
Presidente do júri
Hugo Filipe Abelha Peixoto (Mestrado)
2023 Thesis entitled: Estudo da Influência do Bisfenol a Nas Células Musculares Lisas Vasculares da Artéria Cerebral Média e a Possível Influência no Acidente Vascular Cerebral, University of Beira Interior, October 30.
Presidente do júri
Henrique Elói Albino Costa (Mestrado)
2023 Thesis entitled: Regulation of Gene Expression in Parkinson’s Disease: MicroRNAs as Potential Therapeutic Targets, University of Beir Interior, February 23.
Vogal
Mafalda Proença (Mestrado)
2023 Thesis entitled: The Role of the Glucosensing Receptor Tas1r3 in Glioblastoma, Breast, and Colorectal Cancer Hallmarks, University of Beira Interior, July 6.
Presidente do júri
Inês Rosado de Matos (Mestrado)
2022 Thesis entitled: Targeting neuroinflammation: from target validation to rational design of selective modulators, University of Coimbra, June 1.
Arguente principal
João Pedro dos Reis Luís (Doutoramento)
2022 Thesis entitled: Evaluation of promising MiRNA modulation in neural cells and derived secretomes as therapeutic tools in ALS, University of Lisboa, December 12.
Arguente principal
Marta Isabel da Silva Rodrigues Barbosa (Doutoramento)
2022 Thesis entitled: Processo de senescência celular do envelhecimento biológico: as estratégias senolíticas em fase de ensaios clínicos, University of Beira Interior, March 29.
Vogal
Ana Teresa Cirne Ramos (Mestrado)
2022 Thesis entitled: Intranasal administration of Simvastatin for neuroprotection: Development of Micro and Nanoemulsions for intranasal delivery of Simvastatin in ischemic stroke, University of Beira Interior, July 28.
Presidente do júri
Francisco Gama Sousa (Mestrado)
2022 Thesis entitled: Avaliação da capacidade neuroprotetora de uma nova formulação inibidora da NOX1 para a doença de Parkinson, University of Beira Interior, July 28.
Presidente do júri
Beatriz Serra Almeida (Mestrado)
2022 Thesis entitled: Role of MicroRNAs on Glial Activity in a Parkinson’s Disease Mouse Model, Universiy of Beira Interior, November 23.
Vogal
Tânia Alexandra Salavessa Silva (Mestrado)
2022 Thesis entitled: Study of Th17 Cells in Patients Under Peritoneal Dialysis, University of Beira Interior, November 22.
Presidente do júri
Inês Rodrigues Barreto (Mestrado)
2021 Thesis entitled: Neuropeptide response in Traumatic Brain Injury, University of Coimbra, December 9.
Arguente principal
José Luis Monteiro Alves (Doutoramento)
2021 Thesis entitled: Assessing the therapeutic role of the secretome from mesenchymal stromal cells in genetic models of Parkinson's Disease based on the overexpression of alpha-synuclein., University of Minho, December 21.
Arguente principal
Cláudia Raquel Ferreira Marques (Doutoramento)
2021 Thesis entitled: Papel da argonauta-2 no secretoma microglial, University of Beira Interior, January 21.
Arguente principal
Joana Ester Borges Batista (Mestrado)
2021 Thesis entitled: Impact of Peripheral Inflammation on the Susceptibility to Neurodegenerative Diseases, University of Beira Interior, November 9.
Vogal
Ana Margarida Gonçalves Candeias do Vale (Mestrado)
2020 Thesis entitled: Transplanting Glial Restricted Precursor into a model of cytogenesis ablation: uncovering the interplay between neuro-and gliogenesis, University of Minho, July 27.
Arguente principal
Joana Catarina Martins Macedo (Mestrado)
2020 Thesis entitled: Relação entre a doença de Parkinson e as Doenças Inflamatórias Gastrointestinais, Experiência Profissionalizante na vertente de Investigação, Farmácia Hospitalar e Comunitária, University of Beira Interior, September 29.
Vogal
Inês Maria Antunes Pires (Mestrado)
2019/07 Thesis entitled: “Mesenchymal stem cells secretome – derived exosomes: Biological nanovesicles for the treatment of Parkinson’s disease?” University of Minho, July 2019.
Arguente principal
Helena Maria Vilaça Faria (Mestrado)
2019/05 Thesis entitled: “Generation of midbrain organoids as a model to study Parkinson's disease.” Université du Luxembourg, May 2019.
Arguente principal
Lisa Maria Smits (Doutoramento)
2019 Thesis entitled: Liquified capsules containing nanogrooved microdiscs and co-encapsulated endothelial and mesenchymal stem cells for bone tissue engineering, University of Aveiro, December 9.
Arguente principal
Mariana da Silva Carreira (Mestrado)
2019 Thesis entitled: Fabrication of two-dimensional (2D) shape-tailored microparticles using wettability contrast-based platforms, University of Aveiro, December 9.
Arguente principal
Mafalda Dias de Campos Neto (Mestrado)
2019 Thesis entitled: Impact of Traumatic Brain Injury on astrocytes: Role of Neuropeptide Y, University of Coimbra, September 9.
Arguente principal
Ana Luísa Marques Bernardo (Mestrado)
2018/10 Thesis entitled: "Uso de Sistemas de Telemonitorização: O Estado da e-Saúde Em Portugal.” University of Beira Interior, October 2018.
Presidente do júri
Joaquim Filipe Pinto Dias (Mestrado)
2018/10 Thesis entitled: “Role of striatal-enriched protein tyrosine phosphatase (STEP) in the control of microglial reactivity” University of Beira Interior, October 2018.
Arguente principal
Débora Alexandra Reste Ferreira (Mestrado)
2018/07 Thesis entitled: “The Role of Novel Transcriptional Regulation Mechanisms In Neurogenesis” University of Beira Interior, June 2018.
Orientador
Ana Catarina Almeida (Mestrado)
2018/06 Thesis entitled: “Desenvolvimento de Um Novo Modelo Para O Estudo do Acidente Vascular Cerebral Perinatal.” University of Beira Interior, June 2018.
Arguente principal
Tânia Vanessa Faustino Mendes (Mestrado)
2018/05 Thesis entitled: “Improving neurite outgrowth in 3D hydrogel matrices by mimicking cell receptor-ECM interactions occurring in neurogenic niches: an engineering approach to develop more efficient neural stem cell hydrogel carriers.” University of Porto, May 2018.
Arguente principal
Ana Rita das Neves Lagarto Bento (Doutoramento)
2018/05 Thesis entitled: “The Parkinson’s disease associated Pink1-Parkin pathway in pathology and development.” Université du Luxembourg, May 2018.
Arguente principal
Javier Jarazo (Doutoramento)
2017/12 Thesis entitled: “Role of glial cells as contributors to the onset and propagation of ALS disease.” University of Lisboa, December 2017.
Arguente principal
Joana Carolina Marinho Cunha (Doutoramento)
2017/07 Thesis entitled: “Exosomes-Based Therapy for Stroke” University of Coimbra, July 2017.
Arguente principal
António José da Silva Santinha (Mestrado)
2017/07 Thesis entitled: “Novel transcriptional regulation mechanisms associated with Parkinson’s disease pathogenesis: from biological activity towards therapy” University of Beira Interior, July 2017.
Orientador
Jéssica Nunes (Mestrado)
2017/02 Thesis entitled: “Brain-like endotelial cells derived from stem cells to study BBB development and targeting”.University of Coimbra, February 2017.
Arguente
Catarina Oliveira Praça de Almeida (Doutoramento)
2016/06 Thesis entitled: “Enhancement of endogenous neurogenesis by nitric oxide: Identification of S-nitrosylation targets” University of Algarve, June 2016.
Arguente principal
Ana Isabel Reis dos Santos (Doutoramento)
2016/05 Thesis entitled: “The role of Tau protein in the stress-induced changes in adult hippocampal neurogenesis.” University of Minho, May 2016.
Arguente principal
Chrysoula Dioli (Mestrado)
2016/03 Thesis entitled: “Therapeutic potential of retinoic acid-loaded nanoparticles for brain repair”. University of Coimbra, March 2016.
Vogal
Tiago Alexandre Ramos Teixeira de Sousa Santos (Doutoramento)
2016/01 Thesis entitled: “The role of neudesin in the brain: disclosing a potential sex-dependent action.” University of Minho, January 2016.
Arguente principal
Alberto Abreu da Silva (Mestrado)
2015/11 Thesis entitled: “Modulation of Microglial Activity By GDNF.” University of Beira Interior, November 2015.
Arguente principal
Diogo Alexandre da Silva Tomé (Mestrado)
2015/06 Thesis entitled: “Relationship between the adenosine A1 receptor and cGMP levels in the hippocampus: implications on neurotransmission and synaptic plasticity” University of Beira Interior, June 2015.
Vogal
André Santos Romão Serpa (Doutoramento)
2015/06 Thesis entitled: “Características Valorizadas Num Educador No Ensino da Medicina: Perspetivas de Alunos, Docentes Em Meio Clínico e Docentes Em Meio Não Clínico.” University of Beira Interior, June 2015.
Presidente do júri
João Pedro Gameiro Lopes (Mestrado)
2015/06 Thesis entitled: “Estudo dos Problemas Emocionais e de Comportamento Em Crianças Descendentes de Mães Com Doença Afetiva.” University of Beira Interior, June 2015.
Presidente do júri
Maria Inês da Silva Gonçalves (Mestrado)
2015/06 Thesis entitled: “Multirresistência Bacteriana – Uma “Nova” Terapêutica: Bacteriófagos” University of Beira Interior, June 2015.
Presidente do júri
José Eduardo Cardoso da Rosa (Mestrado)
2015/05 Thesis entitled: “Modulation of retinal ganglion cell function and implications for neuroprotection” University of Coimbra, May 2015.
Arguente principal
João Filipe da Costa Martins (Doutoramento)
2015/04 Thesis entitled: “In vivo single cell analysis reveals distinct behavior of neural stem and progenitor cells in homeostasis and regeneration in the adult brain” University of Coimbra, April 2015.
Vogal
Joana Santos Barbosa (Doutoramento)
2015/02 Thesis entitled: “Impact of methamphetamine on dentate gyrus neurogenesis: The underlying mechanisms and the role of neuropeptide Y”. University of Coimbra, February 2015.
Vogal
Ana Sofia Simões Bento Baptista (Doutoramento)
2015/02 Thesis entitled: “Study of the molecular mechanisms involved in cardiac and neuronal differentiation of embryonic stem cells” University of Algarve, February 2015.
Arguente principal
Ivette Pacheco Leyva (Doutoramento)
2015/01 Thesis entitled: “Modulation of the Secretome of Mesenchymal Stem Cells for Central Nervous System Regenerative Medicine Applications” University of Minho, January 2015.
Arguente principal
Fábio Gabriel Rodrigues Teixeira (Doutoramento)
2014/11 Thesis entitled: “Neuro-glia-vascular alterations by common neonatal clinical conditions” University of Lisboa, November 2014.
Arguente
Filipa Solange Parreira Lourenço Cardoso (Doutoramento)
2014/09 Thesis entitled: “Nuclear and mitochondrial controlo of the apoptosis machinery regulates neural stem cell fate” University of Lisboa, September 2014.
Arguente principal
Joana Mafalda Rodrigues Xavier (Doutoramento)
2014/07 Thesis entitled: “Regulação dos genes circadianos Per1 e Per2 pelo estradiol em células epiteliais do Plexo Coróide.” University of Beira Interior, July 2014.
Arguente principal
Tânia Cristina de Oliveira Albuquerque (Mestrado)
2013/12 Thesis entitled: “Nanomaterials for miRNA delivery and non-invasive imaging in cardiovascular regeneration.” University of Coimbra, December 2013.
Vogal
Renata Sofia Mota Gomes (Doutoramento)
2013/12 Thesis entitled: “Unraveling the biological role of neudesin, a novel neurotrophic factor.” University of Minho, December 2013.
Arguente principal
Ashley da Cruz Novais (Doutoramento)
2013/12 Thesis entitled: “Migration and differentiation of neuronal precursors in the postnatal brain: insights from the subventricular zone and cerebellum” Nova University of Lisboa, December 2013.
Vogal
Maria Francisca Santos Eiriz (Doutoramento)
2013/11 Thesis entitled: “Histamine modulates dopaminergic neuronal survival by boosting microglial activity.” University of Beira Interior, November 2013.
Orientador
Tatiana Filipa Melo Saraiva (Mestrado)
2013/07 Thesis entitled: “Effects of exposure to eslicarbazepine acetate and to other antiepileptic drugs on neurotoxicity and hippocampal development” University of Coimbra, July 2013.
Arguente principal
Maria Inês Frade Marquez Varela Morte (Doutoramento)
2013/07 Thesis entitled: “Ritmo circadiano no plexo coroideu: Influência das hormonas sexuais”, University of Beira Interior, July 2013.
Arguente principal
Cláudia Marisa Fernandes Sousa (Mestrado)
2013/07 Thesis entitled: “Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model of Parkinson’s disease.” University of Beira Interior, July 2013.
Orientador
Marta Raquel Carrola Esteves (Mestrado)
2012/11 Thesis entitled: “Histamine modulates nitric oxide release by microglia and dopaminergic neuronal survival”, University of Beira Interior, November 2012.
Orientador
Joel Pereira Pires (Mestrado)
2012/06 Thesis entitled: “The role of Tumor Necrosis factor receptor 1 in diabetic retinophaty: contribution to the early neuronal cell death” University of Coimbra, June 2012.
Arguente principal
Gabriel Nascimento Ferreira da Costa (Doutoramento)
2011/09 Thesis entitled: “Stimulation of Neural Stem Cell Proliferation by inhibition of phosphatidiesterase 5”, University of Coimbra, September 2011.
Arguente principal
Ana Isabel Reis dos Santos (Mestrado)
2011/07 Thesis entitled: “Methamphetamine induces microglial cell death: protective effect of Interleukine-6”, University of Coimbra, July 2011.
Arguente principal
Vanessa Filipa Coelho Santos (Mestrado)
2010/09 Thesis entitled: “Differential effects of methamphetamine in frontal cortex and striatum: focus on astrogliosis and cell death”, University of Coimbra, September 2010.
Vogal
Sandrine Pontes Machado (Mestrado)
2010/07 Thesis entitled: “Differentiation of neural stem cells by a novel retinoic acid-loaded nanoparticles delivery system”, University of Coimbra, July 2010.
Vogal
Tiago de Sousa Santos (Mestrado)
2010/07 Thesis entitled: “Astrocyte-derived GDNF is a potente inhibitor of microglial activation”, University of Beira Interior, July 2010.
Arguente principal
Sandra Catarina Moreira Rocha (Mestrado)
2010/07 Thesis entitled: “Estudo da protecção de lesões dopaminérgicas exercida por meios condicionados por células estaminais e astrócitos”, University of Beira Interior, July 2010.
Arguente principal
Ana Rita Nunes Parente (Mestrado)

Arbitragem científica em conferência

Nome da conferência Local da conferência
2023/10/11 - 2023/10/13 ETRS & SPCE-TC 2023 Joint Annual Meeting University of Coimbra
2022/07/20 - 2022/07/21 XVII International CICS-UBI Symposium University of Beira Interior
2022/03/11 - 2022/03/12 12th International Meeting of Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC) Braga
2019/11/14 - 2019/11/16 III International Congress in Health Sciences Research - Trends in Aging and Cancer University of Beira Interior
2019/10/10 - 2019/10/12 11th International Meeting of Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC) Lisboa
2019/05/30 - 2019/06/01 XVI Meeting of the Portuguese Society for Neuroscience (SPN) Lisboa
2017/10/12 - 2017/10/14 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies University of Beira Interior
2016/06/30 - 2016/07/01 XI Annual CICS-UBI Symposium University of Beira Interior
2015/11/26 - 2015/11/28 I Congress in Health Sciences Research: Towards Innovation and Entrepreneurship, Trends in Endocrinology and Neurosciences University of Beira Interior
2015/11/19 - 2015/11/20 X Scientific Congress AEFFUP “Neurociência: Um olhar através do cérebro” ICBAS/FFUP, Porto
2015/07/06 - 2015/07/07 X Annual CICS-UBI Symposium University of Beira Interior

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2024 - Atual Neurochemical Research
2023 - Atual Biomaterials Science
2022 - Atual Translational Neurodegeneration
2022 - Atual Molecular Neurobiology
2022 - Atual Molecular Therapy
2022 - Atual Frontiers in Psychiatry | Mood Disorders
2020 - Atual PNAS
2020 - Atual Advanced Science
2019 - Atual Nature Communications (2041-1723) Springer Science and Business Media LLC
2019 - Atual British Journal of Pharmacology (1476-5381) Wiley (Blackwell Publishing)
2019 - Atual Journal of Neurochemistry (1471-4159) Wiley (Blackwell Publishing)
2019 - Atual ACS Nano (1936-086X) American Chemical Society
2019 - Atual Nanoscale (2040-3372) The Royal Society of Chemistry
2019 - Atual Frontiers in Cellular Neuroscience (1662-5102) Frontiers Media SA
2019 - Atual Biomaterials (0142-9612) Elsevier
2019 - Atual Stem Cells (1549-4918) Wiley (John Wiley & Sons)
2019 - Atual Scientific Reports (2045-2322) Springer Science and Business Media LLC
2019 - Atual Pharmacology & Therapeutics (0163-7258) Elsevier
2019 - Atual Journal of Controlled Release (0168-3659) Elsevier
2019 - Atual Particle & Particle Systems Characterization (1521-4117) Wiley (John Wiley & Sons)

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2019 - Atual Member of the Assessment Committee for Final Scientific Reports of IC&DT Projects 2019-2022 Foundation for Science and Technology (FCT) (2019 – 2023)
Avaliador
2015/07 - 2019/03 Reviewer of projects - Member of the Scientific Commission of Biosciences for the Mantero Belard Scientific prize, “Santa Casa da Misericórdia de Lisboa”
Avaliador
Santa Casa da Misericórdia de Lisboa, Portugal

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2019 - Atual Scientific Consultant of the biotech company NeuroSov (https://neurosov.com/)

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2021 - Atual Curricular Unit: Advanced Courses III - PhD in Biomedicine Biomedicine (Doutoramento) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2017 - Atual Curricular Unit: Seminar - Biomedical Sciences — 1st Cycle Degree Biomedical Sciences (Licenciatura) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2016 - Atual Curricular Unit: Cell Cultures - Master in Biotechnology Biotechnology (Mestrado) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013 - Atual Curricular Unit: Cellular and Molecular Bases of Medicine - Medicine - Integrated Master Degree Medicine (Mestrado integrado) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013 - Atual Curricular Unit: Neurobiology - Master in Biomedical Sciences Biomedical Sciences (Mestrado) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2012 - Atual Curricular unit: Nervous System and Senses Organs - Medicine - Integrated Master Degree Medicine (Mestrado integrado) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2011/02/02 - Atual Invited Seminar for the Advanced course Adult stem cells - from basic biology to cell replacement therapies of the PDBEB - PhD Program in Experimental Biology and Biomedicine, University of Coimbra. Title: Neural stem cells (Doutoramento) Universidade de Coimbra, Portugal
2010/10/19 - Atual Invited Seminar for the Advanced course Brain repair - tinkering with brain damage of the PDBEB - PhD Program in Experimental Biology and Biomedicine, University of Coimbra. Title: Neuroinflammation as a potential therapeutic target for brain repair (Doutoramento) Universidade de Coimbra, Portugal
2010/05/25 - Atual Invited Seminar for the Advanced course Regenerative Medicine: The bright and the dark side of Inflammation and Neurogenesis in Epilepsy of the Doctoral Programme in Health Sciences, University of Coimbra. Title: Neurogenesis and inflammation (Doutoramento) Universidade de Coimbra, Portugal
2010/01/27 - Atual Invited Seminar for the Advanced course Bioengineering Systems of the PhD Program MIT-Portugal, University of Coimbra. Title: Neuroinflammation in Brain Repair (Doutoramento) Universidade de Coimbra, Portugal
2024/02/16 - 2024/02/16 Invited Seminar for the Advanced course Pathogenic mechanisms in neuropsychiatric and neurodegenerative disorders of the PDBEB - PhD Program in Experimental Biology and Biomedicine, University of Coimbra. Title: CtBP neuroprotective role in toxin-based Parkinson's disease models (Doutoramento) Universidade de Coimbra, Portugal
2017 - 2024 Curricular Unit: Introduction to Biomedical Sciences - Biomedical Sciences — 1st Cycle Degree Biomedical Sciences (Licenciatura) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2023/01/30 - 2023/01/30 Invited Seminar for the Advanced course Neuroscience - Pathogenic mechanisms in neuropsychiatric and neurodegenerative disorders) of the PDBEB - PhD Program in Experimental Biology and Biomedicine, University of Coimbra. Title: MicroRNAs as biomarkers and therapeutic targets for Parkinson's disease (Doutoramento) Universidade de Coimbra, Portugal
2022/04/12 - 2022/04/12 Invited Seminar for the Advanced course Advanced Therapies of the PDBEB - PhD Program in Experimental Biology and Biomedicine, University of Coimbra. Title: MicroRNA-based therapeutic approaches for Parkinson's disease (Doutoramento) Universidade de Coimbra, Portugal
2018 - 2022 Curricular Unit: Neuroscience of Vision - Optometry and Vision Sciences — 1st Cycle Degree Optometry and Vision Sciences (Licenciatura) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013 - 2021 Curricular Unit: Laboratory rotations - PhD in Biomedicine Biomedicine (Doutoramento) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2019/04/03 - 2019/04/03 Invited Seminar for the Advanced course Neuroscience and Mental Health: A clinical and molecular overview in neuropsychiatric and age-related neurodegenerative disorders of the Doctoral Programme in Health Sciences, University of Coimbra. Title: Regenerative therapeutic approaches for Parkinson’s disease (Doutoramento) Universidade de Coimbra, Portugal
2017 - 2018 Curricular Unit: Human Pathophysiology and Pharmacology - Pharmaceutical Sciences Integrated Master Pharmaceutical Sciences (Mestrado integrado) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2017/02/20 - 2017/02/20 Invited Seminar for the Advanced course Cell and Tissue Engineering-MIT-Portugal Doctoral Program, Bioengineering Focus Area of the PhD Program MIT-Portugal, IST, University of Lisboa. Title: Neural Stem Cells (Doutoramento) Universidade de Lisboa, Portugal
2016 - 2017 Curricular Unit: Human Anatomy and Physiology I - Pharmaceutical Sciences Integrated Master Pharmaceutical Sciences Integrated Master (Mestrado integrado) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2016 - 2017 Curricular Unit: Advanced Course Molecular Mechanisms of Neurodegeneration - PhD in Biomedicine Biomedicine (Doutoramento) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2016/02/12 - 2016/02/12 Invited Seminar for the Advanced course Cell and Tissue Engineering-MIT-Portugal Doctoral Program, Bioengineering Focus Area of the PhD Program MIT-Portugal, IST, University of Lisboa. Title: Nanomedicine approaches to modulate neural stem cells in brain repair (Doutoramento) Universidade de Lisboa, Portugal
2013 - 2016 Curricular Unit: Cellular and Molecular Biology - Biomedical Sciences — 1st Cycle Degree Biomedical Sciences (Licenciatura) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2015/03/05 - 2015/03/05 Invited Seminar for the Advanced course Cell and Tissue Engineering-MIT-Portugal Doctoral Program, Bioengineering Focus Area of the PhD Program MIT-Portugal, IST, University of Lisboa. Title: Neural stem cells: basic concepts and future prospects for brain repair therapies (Doutoramento) Universidade de Lisboa, Portugal
2014/02/28 - 2014/02/28 Invited Seminar for the Advanced course Cell and Tissue Engineering-MIT-Portugal Doctoral Program, Bioengineering Focus Area of the PhD Program MIT-Portugal, IST, University of Lisboa. Title: Neural stem cells in brain repair therapies (Doutoramento) Universidade de Lisboa, Portugal
2013 - 2014 Curricular Unit: Neurophysiology - Biomedical Sciences — 1st Cycle Degree Biomedical Sciences (Licenciatura) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2012 - 2014 Curricular Unit: Digestive System - Medicine - Integrated Master Degree Medicine (Mestrado integrado) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013/02/18 - 2013/02/18 Invited Seminar for the Advanced course Brain and ocular diseases: How to overcome the barriers? From basic science to imaging approaches of the Doctoral Programme in Health Sciences, University of Coimbra. Title: Blood-brain barrier: a crucial frontier that controls neuroinflammation and neurogenesis (Doutoramento) Universidade de Coimbra, Portugal
2012/11/19 - 2012/11/19 Invited Seminar for the Advanced course Stem Cells and Human Health 2012- Stem Cells And Development of the Doctoral Programme in Health Sciences, University of Coimbra. Title: Neural stem cells and nanotechnology in brain repair therapies (Doutoramento) Universidade de Coimbra, Portugal
2011 - 2012 Curricular Unit: Neurobiology - Biomedical Sciences - 1st degree cycle Biomedical Sciences (Licenciatura) Universidade Católica Portuguesa, Portugal
2010 - 2011 Curricular Unit: Immunobiology - Integrated Master's Degree in Dental Medicine Dental Medicine (Mestrado) Universidade Católica Portuguesa, Portugal
2010 - 2011 Curricular Unit: Topics in Biomedicine - Biomedical Sciences - 1st degree cycle Biomedical Sciences (Licenciatura) Universidade Católica Portuguesa, Portugal
2010 - 2011 Curricular Unit: Biomolecular Laboratories - Biomedical Sciences - 1st cycle degree Biomedical Sciences Universidade Católica Portuguesa, Portugal
2010 - 2011 Curricular Unit: Integrative Unit I and II - Integrated Master's Degree in Dental Medicine Dental Medicine (Mestrado integrado) Universidade Católica Portuguesa, Portugal
2009/03/25 - 2009/03/25 Invited Seminar for the Advanced course Neurogenesis of the PDBEB - PhD Program in Experimental Biology and Biomedicine, University of Coimbra. Title: Neuroinflammation in neurodegeneration and neurogenesis (Doutoramento) Universidade de Coimbra, Portugal
2008/04/02 - 2008/04/02 Invited Seminar for the Advanced course Neuroimmunology of the PDBEB - PhD Program in Experimental Biology and Biomedicine, University of Coimbra. Title: Contribution of neuroinflammation to excitotoxicity and neurogenesis (Doutoramento) Universidade de Coimbra, Portugal
2006/01/16 - 2006/01/16 Invited pratical hands-on section for the Advanced course Neuromodulation of the PDBEB - PhD Program in Experimental Biology and Biomedicine, University of Coimbra. Title: Organotypic cultures (Doutoramento) Universidade de Coimbra, Portugal

Membro de associação

Nome da associação Tipo de participação
2005 - Atual Portuguese Society for Neuroscience (SPN), Portugal.
2005 - Atual Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2024 - Atual Member of PhD thesis committee of Inês Torquato Afonso of the PhD Program in Biomedical Sciences of the University of Algarve
Membro
Universidade do Algarve, Portugal
2023 - Atual Member of PhD thesis committee of Alessander Leyendecker Junior of the PhD Program in Health Sciences of the University of Minho
Membro
Universidade do Minho, Portugal
2023 - Atual Member of PhD thesis committee of Carla Sofia Teixeira Cavaleiro of the Doctoral Programme in Experimental Biology and Biomedicine (PDBEB), University of Coimbra
Membro
Universidade de Coimbra, Portugal
2022 - Atual Member of PhD thesis committee of João Pedro Novo of the Doctoral Programme in Experimental Biology and Biomedicine (PDBEB), University of Coimbra
Membro
Universidade de Coimbra, Portugal
2021 - Atual Member of PhD thesis committee of Sara Paulo of the Doctoral Programme of the Academic Center of Lisboa, University of Lisboa
Membro
Universidade de Lisboa, Portugal
2021 - Atual Member of PhD thesis committee of Mariana Pais of the Doctoral Programme of Biomedical Egineering, University of Coimbra
Membro
Universidade de Coimbra, Portugal
2020 - Atual Member of PhD thesis committee of Tiago Almeida of the Doctoral Programme of Biomedical Sciences, University of Porto
Membro
Universidade do Porto, Portugal
2017 - 2020 Member of PhD thesis committee of Ricardo Abreu of the Doctoral Programme in Experimental Biology and Biomedicine, University of Coimbra
Membro
Universidade de Coimbra, Portugal

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2022 - Atual Reviewer of projects - EIC Pathfinder Open, EU-Brussels (2022, 2023)
2022 - Atual Reviewer of projects - FAPESP - Fundação de Amparo à Pesquisa do Estado de São Paulo, Brasil (2022)
2021 - Atual Reviewer of projects - National Science Foundation (NSF), USA (2021)
2018 - Atual Reviewer of projects - Deutsche Forschungsgemeinschaft (DFG), German Research Foundation (2018, 2021)
2018 - Atual Reviewer of projects - National Science Centre, Poland (Narodowe Centrum Nauki – NCN (2018)
2017 - Atual Reviewer of projects - Israeli Ministry of Science, Technology and Space, Call for Proposals 2016: Research Program "Applied and - Engineering Researches 2017" (2017)
2016 - Atual Reviewer of projects - European Commission, Marie Sklodowska-Curie actions (2016, 2017, 2019, 2021, 2022, 2023)
2016 - Atual Reviewer of projects - MRCG/HRB Joint Funding Scheme 2016, Epilepsy Ireland (2016)
2016 - Atual Reviewer of projects - European Cooperation in Science and Technology (COST actions), EU-Brussels (2016)
2016 - Atual Reviewer of projects - National Research Foundation (NRF), South Africa (2016)
2012 - Atual Reviewer of projects - Medical Research Council (MRC, UK, 2012)
2014 - 2018 Reviewer of projects - Portuguese funding agency FCT (2014, 2015, 2018)
Distinções

Prémio

2017 Co-author of Best Poster - Nunes J, Afonso M, Santos T, Esteves M, Cristóvão AC, Bernardino L (2017) Novel transcriptional regulation mechanisms associated with Parkinson’s disease pathogenesis", II International Congress in Health Sciences Research.
2017 Co-author of Best Poster - Barata-Antunes S, Cristóvão AC, Machado-Pereira M, Santos T, Saraiva C, Ferreira R, Bernardino L (2017) Unveiling a novel crosstalk between histamine and lipopolysaccharide in the modulation of in the hippocampus.
Universidade do Minho, Portugal
2015 Co-author of the Best Oral Communication - Saraiva CM, Paiva J, Santos T, Ferreira L, Bernardino L (2015) MicroRNA-loaded nanoparticles as modulators of neurogenesis in the subventricular zone. X Annual CICS Symposium
Universidade da Beira Interior, Portugal
2013 Co-author of the Pulido Valente Science Prize 2013 to the work - Santos T, et al, Ferreira L, Bernardino L. Polymeric nanoparticles to control the differentiation of neural stem cells in the subventricular zone of the brain. (10K euros)
Fundação Professor Francisco Pulido Valente, Portugal
2011 Medal of Honor L´Oreal Portugal for Women in Science (7th edition, 2011) Award attributed to Liliana Bernardino for a project in the field of neurogenesis and Parkinson’s disease.
2011 Co-author of the Best Oral Communication - Santos T, et al, Bernardino L (2011) Intracellular Delivery of Retinoic Acid-Loaded Nanoparticles Modulates Neuronal Differentiation of Stem cells; 6th SPCE-TC Annual Meeting, Biocant
2010 Co-author of the Best Oral Communication - Eiriz MF, Bernardino L, Xapelli S, Grade S, Rosa A, Cortes L, Agasse F, Ferreira L, Malva JO (2010) Histamine releasing PLGA microparticles as a new way to drive brain repair. 5th Annual Meeting of the SPCE-TC
Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
2008 Calouste Gulbenkian Foundation Award (2008) Award attributed to Liliana Bernardino for a project in the neural stem cells and cancer field.

Outra distinção

2021 Selected for the book Women in Science, by Ciência Viva, 2021, ISBN: 978-989-54649-5-1
Ciência Viva, Portugal
2010 Travel grant, Congress “ESTOOLS- International Symposium: Stem Cells in Biology and Disease”. Promoting entity: Organization Committee of the congress.
2008 Travel grant, 3rd Meeting of the Portuguese Society for Stem Cells and Cell Therapy. Promoting entity: Portuguese Society for Stem Cells and Cell Therapy.
2008 Travel grant, 6th FENS Forum of European Neuroscience, Geneva, Switzerland. Promoting entity: Federation of European Neuroscience (FENS)
2008 Travel grant, Annual SfN meeting, Washington. Promoting entity: Calouste Gulbenkian Foundation
2007 Travel grant, 2nd Meeting of the Portuguese Society for Stem Cells and Cell Therapy. Promoting entity: Portuguese Society for Stem Cells and Cell Therapy
2006 Travel grant, Annual SfN meeting, Atlanta, USA. Promoting entity: FLAD- Luso American Foundation
2006 Travel grant, 1st Meeting of the Portuguese Society for Stem Cells and Cell Therapy. Promoting entity: Portuguese Society for Stem Cells and Cell Therapy
2005 ISN/ESN Travel grant, 20th Biennial Meeting of Neurochemistry, Innsbruck. Promoting entity: ISN/ESN-International Society for Neurochemistry/ European Society for Neurochemistry
2005 FLAD Travel grant, Annual SfN meeting, Washington. Promoting entity: FLAD- Luso American Foundation