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Identificação

Identificação pessoal

Nome completo
Ricardo Lagoa

Identificadores de autor

Ciência ID
5C18-A29A-44AB
ORCID iD
0000-0003-2375-6612
Researcher Id
AEV-0520-2022
Scopus Author Id
23051352300
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2011/11/29 - Atual Professor Adjunto (Docente Ensino Superior Politécnico) Instituto Politécnico de Leiria Escola Superior de Tecnologia e Gestão, Portugal
2000/10/01 - 2011/11/28 Assistente (Docente Ensino Superior Politécnico) Instituto Politécnico de Leiria, Portugal
Projetos

Projeto

Designação Financiadores
2018/10/01 - 2022/09/30 Multifunctional biomolecular systems for new methods of decontamination, protection and toxicological assessment
PTDC/BIA-MIB/31864/2017
Investigador responsável
Instituto Politécnico de Leiria, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Marques-da-Silva, Dorinda; Mal, Sib Sankar; Aureliano, Manuel; Lagoa, Ricardo. "The Growth Curve Method to Rapidly Derive the Antibacterial Potential of Polyoxovanadates". Trabalho apresentado em Biosystems in Toxicology and Pharmacology – Current Challenges (BiTaP 2022), 2022.
    Publicado • 10.3390/bitap-12790
  2. Silva, João; Videira, Paula Alexandra Quintela; Lagoa, Ricardo. "Bioactivity gradients of cytoprotective and anticancer catechins in skin: Simulation studies for the design of controlled release systems". Trabalho apresentado em 5th Portuguese Meeting on Bioengineering, Coimbra, 2017.
    Publicado • 10.1109/enbeng.2017.7889467
  3. Mendes, Ausenda; Lagoa, Ricardo; Bártolo, Paulo. "Rapid prototyping system for tissue engineering". Trabalho apresentado em 1st International Conference on Advanced Research on Virtual and Rapid Prototyping, 2003.
    Publicado
Artigo em revista
  1. João Lopes et al.. "Cardiolipin membranes promote cytochrome c transformation of polycyclic aromatic hydrocarbons and their in vivo metabolites". Molecules (2024):
    Aceite para publicação
  2. López-Sánchez, Carmen; Lagoa, Ricardo; Poejo, Joana; García-López, Virginio; García-Martínez, Virginio; Gutierrez-Merino, Carlos. "An Update of Kaempferol Protection against Brain Damage Induced by Ischemia-Reperfusion and by 3-Nitropropionic Acid". Molecules 29 4 (2024): 776. http://dx.doi.org/10.3390/molecules29040776.
    10.3390/molecules29040776
  3. Marques-da-Silva, Dorinda; Lagoa, Ricardo. "Rafting on the Evidence for Lipid Raft-like Domains as Hubs Triggering Environmental Toxicants’ Cellular Effects". Molecules 28 18 (2023): 6598. http://dx.doi.org/10.3390/molecules28186598.
    10.3390/molecules28186598
  4. Pal, Dilipkumar; Raj, Khushboo; Nandi, Shyam Sundar; Sinha, Surajit; Mishra, Abhishek; Mondal, Arijit; Lagoa, Ricardo; Burcher, Jack T.; Bishayee, Anupam. "Potential of Synthetic and Natural Compounds as Novel Histone Deacetylase Inhibitors for the Treatment of Hematological Malignancies". Cancers 15 10 (2023): 2808. http://dx.doi.org/10.3390/cancers15102808.
    10.3390/cancers15102808
  5. Ghanbari-Movahed, Maryam; Shafiee, Sahar; Burcher, Jack T.; Lagoa, Ricardo; Farzaei, Mohammad Hosein; Bishayee, Anupam. "Anticancer Potential of Apigenin and Isovitexin with Focus on Oncogenic Metabolism in Cancer Stem Cells". Metabolites 13 3 (2023): 404. http://dx.doi.org/10.3390/metabo13030404.
    10.3390/metabo13030404
  6. Arunachalam, Kannappan; Pandurangan, Poonguzhali; Shi, Chunlei; Lagoa, Ricardo. "Regulation of Staphylococcus aureus Virulence and Application of Nanotherapeutics to Eradicate S. aureus Infection". Pharmaceutics 15 2 (2023): 310. http://dx.doi.org/10.3390/pharmaceutics15020310.
    10.3390/pharmaceutics15020310
  7. Marques-da-Silva, Dorinda; Lopes, João M.; Correia, Iris; Silva, João S.; Lagoa, Ricardo. "Removal of Hydrophobic Organic Pollutants and Copper by Alginate-Based and Polycaprolactone Materials". Processes 10 11 (2022): 2300. http://dx.doi.org/10.3390/pr10112300.
    Acesso aberto • 10.3390/pr10112300
  8. Lopes, João M.; Marques-da-Silva, Dorinda; Videira, Paula Q.; Lagoa, Ricardo L.. Autor correspondente: Lagoa, Ricardo L.. "Comparison of Laccases and Hemeproteins Systems in Bioremediation of Organic Pollutants". Current Protein & Peptide Science 23 6 (2022): 402-423. http://dx.doi.org/10.2174/1389203723666220704090416.
    10.2174/1389203723666220704090416
  9. Renu, Kaviyarasi; Mukherjee, Anirban Goutam; Wanjari, Uddesh Ramesh; Vinayagam, Sathishkumar; Veeraraghavan, Vishnu Priya; Vellingiri, Balachandar; George, Alex; et al. "Misuse of Cardiac Lipid upon Exposure to Toxic Trace Elements - A Focused Review". Molecules 27 17 (2022): 5657. http://dx.doi.org/10.3390/molecules27175657.
    10.3390/molecules27175657
  10. Marques-da-Silva, Dorinda; Videira, Paula Alexandra; Lagoa, Ricardo. "Registered human trials addressing environmental and occupational toxicant exposures: Scoping review of immunological markers and protective strategies". Environmental Toxicology and Pharmacology 93 (2022): 103886. http://dx.doi.org/10.1016/j.etap.2022.103886.
    Acesso aberto • 10.1016/j.etap.2022.103886
  11. Lagoa, Ricardo; Marques-da-Silva, Dorinda; Diniz, Mário; Daglia, Maria; Bishayee, Anupam. Autor correspondente: Lagoa, Ricardo. "Molecular mechanisms linking environmental toxicants to cancer development: Significance for protective interventions with polyphenols". Seminars in Cancer Biology 80 (2022): 118-144. http://dx.doi.org/10.1016/j.semcancer.2020.02.002.
    10.1016/j.semcancer.2020.02.002
  12. Silva, João; Marques-da-Silva, Dorinda; Lagoa, Ricardo. Autor correspondente: Lagoa, Ricardo. "Reassessment of the experimental skin permeability coefficients of polycyclic aromatic hydrocarbons and organophosphorus pesticides". Environmental Toxicology and Pharmacology 86 (2021): 103671. http://dx.doi.org/10.1016/j.etap.2021.103671.
    10.1016/j.etap.2021.103671
  13. Silva, João; Vanat, Pavlo; Dorinda Marques-da-Silva; Rodrigues, Joaquim; Lagoa, Ricardo. Autor correspondente: Lagoa, Ricardo. "Metal alginates for polyphenol delivery systems: Studies on crosslinking ions and easy-to-use patches for release of protective flavonoids in skin". Bioactive Materials 5 3 (2020): 447-457. http://dx.doi.org/10.1016/j.bioactmat.2020.03.012.
    Acesso aberto • 10.1016/j.bioactmat.2020.03.012
  14. Kannappan, Arunachalam; Durgadevi, Ravindran; Srinivasan, Ramanathan; Lagoa, Ricardo; Packiavathy, Issac Abraham Sybiya Vasantha; Pandian, Shunmugiah Karutha; Veera Ravi, Arumugam. "2-Hydroxy-4-methoxybenzaldehyde from Hemidesmus indicus is antagonistic to Staphylococcus epidermidis biofilm formation". Biofouling 36 5 (2020): 549-563. http://dx.doi.org/10.1080/08927014.2020.1777989.
    10.1080/08927014.2020.1777989
  15. Lagoa, Ricardo; Silva, João; Rodrigues, Joaquim; Anupam Bishayee. Autor correspondente: Lagoa, Ricardo. "Advances in phytochemical delivery systems for improved anticancer activity". Biotechnology Advances 38 (2020): https://doi.org/10.1016/j.biotechadv.2019.04.004.
    10.1016/j.biotechadv.2019.04.004
  16. Kim, Doo Hwan; Khan, Haroon; Ullah, Hammad; Hassan, Sherif T.S.; Šmejkal, Karel; Efferth, Thomas; Mahomoodally, Mohamad Fawzi; et al. "MicroRNA targeting by quercetin in cancer treatment and chemoprotection". Pharmacological Research 147 (2019): 104346. http://dx.doi.org/10.1016/j.phrs.2019.104346.
    Publicado • 10.1016/j.phrs.2019.104346
  17. Rengasamy, K.R.R.; Khan, H.; Gowrishankar, S.; Lagoa, Ricardo; Mahomoodally, F.M.; Khan, Z.; Suroowan, S.; et al. "The role of flavonoids in autoimmune diseases: Therapeutic updates". Pharmacology and Therapeutics 194 (2019): 107-131. https://doi.org/10.1016/j.pharmthera.2018.09.009.
    Publicado • 10.1016/j.pharmthera.2018.09.009
  18. Silva, Dorinda; Gil Fraqueza; Lagoa, Ricardo; Anjana Anandan Vannathan; Sib Sankar Mal; Manuel Aureliano. "Polyoxovanadate inhibition of Escherichia coli growth shows a reverse correlation with Ca2+-ATPase inhibition". New Journal of Chemistry 43 45 (2019): 17577-17587. https://doi.org/10.1039/C9NJ01208G.
    Publicado • 10.1039/C9NJ01208G
  19. Lagoa, Ricardo; Arias, Alejandro; Gutierrez-Merino, Carlos. Autor correspondente: Lagoa, Ricardo. "Correlation between the potency of flavonoids for cytochrome c reduction and inhibition of cardiolipin-induced peroxidase activity". BioFactors 43 3 (2017): 451-468. https://doi.org/10.1002%2Fbiof.1357.
    Publicado • 10.1002/biof.1357
  20. Arias, Alejandro; López-Sánchez, C.; Silva, Dorinda; Lagoa, Ricardo; Garcia-Lopez, V.; García-Martínez, V.; Gutierrez-Merino, Carlos. "High expression of cytochrome b 5 reductase isoform 3/cytochrome b 5 system in the cerebellum and pyramidal neurons of adult rat brain". Brain Structure and Function 221 4 (2016): 2147-2162. https://link.springer.com/article/10.1007/s00429-015-1036-5.
    Publicado • 10.1007/s00429-015-1036-5
  21. Liu, Feng; Lee, Dong-Hoon; Lagoa, Ricardo; Kumar, Sandeep. "New frontiers in biomedical science and engineering during 2014–2015 (Guest Editorial)". Bio-Medical Materials and Engineering 26 s1 (2015): 3-7. https://content.iospress.com/articles/bio-medical-materials-and-engineering/bme1283.
    Publicado • 10.3233/BME-151283
  22. Lagoa, Ricardo; Gañán, Carlos; López-Sánchez, Carmen; García-Martínez, Virginio; Gutierrez-Merino, Carlos. "The decrease of NAD(P)H:quinone oxidoreductase 1 activity and increase of ROS production by NADPH oxidases are early biomarkers in doxorubicin cardiotoxicity". Biomarkers 19 2 (2014): 142-153. http://hdl.handle.net/10400.8/2352.
    Publicado • 10.3109/1354750X.2014.885084
  23. Gutierrez-Merino, Carlos; Lopez-Sanchez, C.; Lagoa, Ricardo; Arias, Alejandro; Bueno, C.; Garcia-Martinez, V.. "Neuroprotective actions of flavonoids". Current Medicinal Chemistry 18 8 (2011): 1195-1212. https://doi.org/10.2174/092986711795029735.
    Publicado • 10.2174/092986711795029735
  24. Lagoa, Ricardo; Graziani, I.; Lopez-Sanchez, C.; Garcia-Martinez, V.; Gutierrez-Merino, Carlos. "Complex I and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria". Biochimica et Biophysica Acta - Bioenergetics 1807 12 (2011): 1562-1572. https://doi.org/10.1016/j.bbabio.2011.09.022.
    Acesso aberto • Publicado • 10.1016/j.bbabio.2011.09.022
  25. Lagoa, Ricardo; Rodrigues, Joaquim. Autor correspondente: Lagoa, Ricardo. "Kinetic analysis of metal uptake by dry and gel alginate particles". Biochemical Engineering Journal 46 3 (2009): 320-326. http://dx.doi.org/10.1016/j.bej.2009.06.007.
    Publicado • 10.1016/j.bej.2009.06.007
  26. Lagoa, Ricardo; Lopez-Sanchez, C.; Arias, Alejandro; Gañan, C.M.; Garcia-Martinez, V.; Gutierrez-Merino, Carlos. "Kaempferol protects against rat striatal degeneration induced by 3-nitropropionic acid". Journal of Neurochemistry 111 2 (2009): 473-487. https://doi.org/10.1111/j.1471-4159.2009.06331.x.
    Acesso aberto • Publicado • 10.1111/j.1471-4159.2009.06331.x
  27. Silva, Rui M. P.; Manso, João P. H.; Rodrigues, Joaquim; Lagoa, Ricardo. Autor correspondente: Lagoa, Ricardo. "A comparative study of alginate beads and an ion-exchange resin for the removal of heavy metals from a metal plating effluent". Journal of Environmental Science and Health, Part A 43 11 (2008): 1311-1317. http://dx.doi.org/10.1080/10934520802177953.
    Publicado • 10.1080/10934520802177953
  28. Lagoa, Ricardo; Rodrigues, Joaquim. Autor correspondente: Lagoa, Ricardo. "Evaluation of Dry Protonated Calcium Alginate Beads for Biosorption Applications and Studies of Lead Uptake". Applied Biochemistry and Biotechnology 143 2 (2007): 115-128. http://dx.doi.org/10.1007/s12010-007-0041-4.
    Publicado • 10.1007/s12010-007-0041-4
  29. Rodrigues, Joaquim; Lagoa, Ricardo. Autor correspondente: Lagoa, Ricardo. "Copper ions binding in Cu-alginate gelation". Journal of Carbohydrate Chemistry 25 2-3 (2006): 219-232. https://doi.org/10.1080/07328300600732956.
    Publicado • 10.1080/07328300600732956
  30. Murtinho, D.; Lagoa, Ricardo; Garcia, F.A.P.; Gil, M.H.. "Cellulose derivatives membranes as supports for immobilisation of enzymes". Cellulose 5 4 (1998): 299-308. https://doi.org/10.1023/A:1009255126274.
    Publicado • 10.1023/A:1009255126274
Capítulo de livro
  1. Aureliano, Manuel; Dorinda, Marques-da-Silva; Serrano, Ana; Martins, João; Faleiro, Leonor; Fonseca, Custôdia; Fraqueza, Gil; Lagoa, Ricardo. "Polyoxometalates with Anticancer, Antibacterial and Antiviral Activities". In Polyoxometalates, 309-358. Jenny Stanford Publishing, 2022.
    Publicado • 10.1201/9781003277446-8
  2. Silva, João S.; Marques-da-Silva, Dorinda; Lagoa, Ricardo. Autor correspondente: Lagoa, Ricardo. "Towards the Development of Delivery Systems of Bioactive Compounds With Eyes Set on Pharmacokinetics". In Modeling and Control of Drug Delivery Systems, 125-144. Elsevier, 2021.
    Publicado • 10.1016/b978-0-12-821185-4.00006-3
  3. Marques-da-Silva, Dorinda; Rodrigues, Joaquim Rui; Lagoa, Ricardo. Autor correspondente: Lagoa, Ricardo. "Anthocyanins, effects in mitochondria and metabolism". In Mitochondrial Physiology and Vegetal Molecules, 267-300. Elsevier, 2021.
    Publicado • 10.1016/b978-0-12-821562-3.00028-9
  4. Lagoa, Ricardo; Gutierrez-Merino, Carlos. "Cytochrome c reducing agents and antiapoptotic action of antioxidants". In Cytochrome C: Roles and Therapeutic Implications, 1-49. New York, Estados Unidos: Nova Science Publishers, 2019.
    Publicado
  5. Silva, Dorinda; Francisco, R.; dos Reis Ferreira, V.; Forbat, L.; Lagoa, Ricardo; Videira, Paula Alexandra Quintela; Witters, P.; Jaeken, J.; Cassiman, D.. "An electronic questionnaire for liver assessment in congenital disorders of glycosylation (LeQCDG): A patient-centered study". 55-64. 2019.
    Publicado • 10.1007/8904_2018_121
  6. Lagoa, Ricardo; Murtinho, Dina; Gil, M.H.. "Membranes of Cellulose Derivatives as Supports for Immobilization of Enzymes (Chapter 15)". In ACS Symposium Series - Biopolymers (Utilizing Nature’s Advanced Materials), 228-234. Washington DC, Estados Unidos: American Chemical Society (Edited by S. Imam, R. Greene and B. Zaidi), 1999.
    Publicado • 10.1021/bk-1999-0723.ch015
Edição de número de revista
  1. Lagoa, Ricardo; Diniz, Mário. "Development of Protective Therapies Facing Toxic Environmental Exposures". Topic Issue associated to different Journals (2022): https://www.mdpi.com/topics/therapy_toxic.
    Publicado • Co-editor