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Maria Ester Coutinho completed a Medical Degree at the University of Porto and a medical specialisation in Neurology at the Hospital Santo Antonio, Porto, Portugal. She was an awardee of the studentship from the Gulbenkian Programme for Advanced Medical Education and completed a DPhil degree (PhD equivalent in Oxford) in Clinical Neurosciences at the Nuffield Department of Clinical Neuroscience, University of Oxford in 2017. Following her PhD studies, she worked as a clinical postdoctoral research fellow at the Institute of Psychiatry, Psychology & Neurosciences and as an MRC Centre for Developmental Neurobiology clinical fellow at King's College London. Alongside her research at KCL, she worked as a Neurology consultant at King's College Hospital until June 2023, where she established and led a multidisciplinary specialist clinic for patients with neurological autoimmune diseases, and pioneered the neurology and neuropsychiatry pathway in one of the first national NHSE-funded specialist clinics for Post-COVID-19 syndrome (long COVID). In 2021 she was awarded a contract by the Fundacao Ciencia e Tecnologia (FCT) under the Individual Scientific Employment Stimulus call, which led her to take a junior researcher position at The Center for Neuroscience and Cell Biology (CNC) at the University of Coimbra. She published 40 academic papers (14 in the last 5 years, total citation >2000, h-index 23) (source: Google Scholar). Since becoming a Junior Researcher at the CNC she received 3 awards (as the PI) from the FCT, Brain Behaviour and Research Foundation and Sociedade Portuguesa de Neurologia (Total funding: 123K Euro). Alongside her clinical and research work, she was a module leader for the MSc in Clinical Neuropsychiatry at King's College Hospital (module: Scientific Foundations of Neuropsychiatry) and is an Invited Assistant Professor of the Medical course at the Católica Medical School, Lisbon (coordinator - module: Thinking and doing I; co-coordinator - module: Thinking and doing II). She currently supervises 1 PhD student and 2 MSc students. She organised and co-chaired a symposium of the Federation of European Neuroscience Societies Regional Meeting in 2023. She is a thesis comittee member of two ongoing PhD studies and was the main examiner of one master's thesis. She is a frequent invited speaker of seminars/lectures at international conferences or research institutes. She was awarded the Pre-Doctoral Plenary Competition first prize by the Academy of Medical Sciences, UK. She works in the areas of Medical & Health Sciences, with an emphasis on Neurology and Neuroimmunology.
Identificação

Identificação pessoal

Nome completo
Maria Ester Freitas Barbosa Pereira Coutinho

Nomes de citação

  • Coutinho, Ester

Identificadores de autor

Ciência ID
8A15-1EA8-C0AA
ORCID iD
0000-0002-5688-8198

Endereços de correio eletrónico

  • mcoutinho@uc.pt (Profissional)
  • ester.coutinho@kcl.ac.uk (Profissional)
  • mecoutinho@ucp.pt (Profissional)

Moradas

  • Center for Neuroscience and Cell Biology & Department of Life Sciences University of Coimbra Portugal, 3004-504 , Coimbra, Coimbra, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Clínica - Neurologia Clínica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
2012/10 - 2017/04
Concluído
DPhil in Clinical Neurosciences (Doctor of Philosophy)
University of Oxford, Reino Unido
"Central Nervous System autoimmunity in neuropsychiatric disorders" (TESE/DISSERTAÇÃO)
2011/10 - 2012/05
Concluído
Programme for Advanced Medical Education (Outros)
Instituto Gulbenkian de Ciência, Portugal

Fundação para a Ciência e a Tecnologia, Portugal
2006/03 - 2011/03
Concluído
Specialist in Neurology (Especialização pós-licenciatura)
Centro Hospitalar Universitário do Porto EPE - Hospital Geral de Santo António, Portugal
1998/10 - 2004/07
Concluído
Medicine (Licenciatura)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2021/08/01 - Atual Investigador Contratado (Investigação) Universidade de Coimbra, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2021/05/01 - Atual Professor Auxiliar Convidado (Docente Universitário) Universidade Católica Portuguesa, Portugal
Catolica Medical School, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2018/10 - 2023/06 Honorary Neurology Consultant King's College Hospital, Reino Unido
2019/01 - 2021/04/30 Clinical Research Fellow King's College London - Denmark Hill Campus, Reino Unido
2017/11 - 2018/08 Specialty Registrar in Neurology / Stroke King's College Hospital, Reino Unido
2016/08 - 2017/08 Honorary Research Associate University of Oxford Nuffield Department of Clinical Neurosciences, Reino Unido
2006/03 - 2011/03 Médico Interno da Especialidade de Neurologia (Specialist Registrar in Neurology) Centro Hospitalar Universitário do Porto EPE - Hospital Geral de Santo António, Portugal
2005/01 - 2006/03 Médico Interno do Ano Comum (General Medical trainee) Centro Hospitalar de Vila Nova de Gaia EPE Espinho Unidade III, Portugal
Projetos

Bolsa

Designação Financiadores
2023/05/01 - Atual Human centred-design as a vehicle to science communication: a participatory and citizen science research approach
N/a
Investigador
Banco Santander Portugal
2023/03/01 - Atual Understanding the role of maternal IgG antibodies in fetal brain development
N/a
Investigador responsável
Brain and Behavior Research Foundation
2023/03/01 - Atual UNITED - Unravelling Novel Immune Targets in Encephalitic Diseases
N/ a
Investigador responsável
Sociedade Portuguesa de Neurologia
2023/03/01 - Atual MIRACLES - MicroRNAs And Cognition in Longcovid: Exploratory Study
2022.04018.PTDC
Investigador responsável
Fundação para a Ciência e a Tecnologia
2019/04 - Atual SINNAPS2 study: A randomised placebo-controlled trial of immunotherapy in patients with psychosis associated with anti-neuronal membrane antibodies.
MR/N019067/1
Outra
Medical Research Council
Em curso
2023/04/01 - 2026/03/31 Homeostatic plasticity defects in autism: insight from human mutations in the CNTNAP2 gene
202202-30-31
Investigador
Fundació la Marató de TV3
Em curso
2018/06 - 2021/05 Understanding the pathogenesis in CASPR2-antibody autoimmune synaptic encephalitis
PTDC/MED-NEU/29452/2017
Investigador
Fundação para a Ciência e a Tecnologia

Projeto

Designação Financiadores
2021/08/01 - Atual Maternal IgG antibodies: a novel role in the neurodevelopment of the offspring?
2020.03359.CEECIND
Investigador Pós-doutorado
Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2009/04/20 - 2012/10/20 Trends in incidence and outcome of Neurological Attacks: the second population-based study in Northern Portugal
PIC/IC/82858/2007
Investigador
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Administração Regional de Saúde do Norte IP, Portugal

Centro Hospitalar Universitário de Santo António, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Outro

Designação Financiadores
2019/06/01 - 2021/04/30 Maternal IgG antibodies and their role in the neurodevelopment of the offspring
UNK
Bolseiro de Investigação
MRC Centre for Developmental Neurobiology, Reino Unido
Em curso
2019/01 - 2019/12 Inhibition of placental transfer as a therapeutic target in antibody-mediated neurodevelopmental disorders
132871
Investigador
UCB Biopharma SPRL
Concluído
2012/09 - 2017/04 Central nervous system autoimmunity in neuropsychiatric disorders
n/a
Bolseiro de Doutoramento
University of Oxford Nuffield Department of Clinical Neurosciences, Reino Unido
Gulbenkian Programme for Advanced Medical Education
Concluído
2010/01 - 2010/06 Clinical and serological training of the myasthenic syndromes
not available
Bolseiro de Investigação
Oxford Myasthenia Center and Clinical Neuroimmunology Service, Reino Unido
European Federation of Neurological Societies
Concluído
Produções

Publicações

Artigo em revista
  1. Butler, Matt; Abdat, Yasmin; Zandi, Michael; Michael, Benedict D.; Coutinho, Ester; Nicholson, Timothy R.; Easton, Ava; Pollak, Thomas A.. "Mental health outcomes of encephalitis: An international web-based study". European Journal of Neurology 31 1 (2023): http://dx.doi.org/10.1111/ene.16083.
    10.1111/ene.16083
  2. Ward, Catherine; Farag, Mena; Pollak, Thomas A.; Coutinho, Ester; Posporelis, Sotiris. "Suicidal and self-injurious behavior following adalimumab reference-to-generic biosimilar switch". Psychiatry and Clinical Neurosciences 76 2 (2021): 59-62. http://dx.doi.org/10.1111/pcn.13315.
    10.1111/pcn.13315
  3. Ariño, Helena; Coutinho, Ester; Pollak, Thomas A.; Stewart, Robert. "Real-world experience of assessing antibodies against the N-methyl-D-aspartate receptor (NMDAR-IgG) in psychiatric patients. A retrospective single-centre study". Brain, Behavior, and Immunity 98 (2021): 330-336. http://dx.doi.org/10.1016/j.bbi.2021.08.233.
    10.1016/j.bbi.2021.08.233
  4. Coutinho, Ester. "Demystifying the spontaneous phenomena of motor hyperexcitability". Clinical Neurophysiology 132 8 (2021): 1830-1844. http://dx.doi.org/10.1016/j.clinph.2021.03.053.
    10.1016/j.clinph.2021.03.053
  5. Coutinho, Ester. "Inhibition of Maternal-to-Fetal Transfer of IgG Antibodies by FcRn Blockade in a Mouse Model of Arthrogryposis Multiplex Congenita". Neurology - Neuroimmunology Neuroinflammation 8 4 (2021): e1011-e1011. http://dx.doi.org/10.1212/nxi.0000000000001011.
    10.1212/nxi.0000000000001011
  6. Coutinho, Ester. "Psychosis in systemic lupus erythematosus (SLE): 40-year experience of a specialist centre". Rheumatology (2021): http://dx.doi.org/10.1093/rheumatology/keab160.
    10.1093/rheumatology/keab160
  7. Cechin, Laura; Gasmelseed, Jihad; Bashford, James; Rowczenio, Dorota; Reilly, Mary M.; Gillmore, Julian D.; Coutinho, Ester. "Early-Onset Leptomeningeal Manifestation of G47R Hereditary Transthyretin Amyloidosis". Neurology: Clinical Practice 11 5 (2021): e757-e759. http://dx.doi.org/10.1212/cpj.0000000000001054.
    10.1212/cpj.0000000000001054
  8. Thomas A. Pollak; Angela Vincent; Conrad Iyegbe; Ester Coutinho; Leslie Jacobson; Dan Rujescu; James Stone; et al. "Relationship Between Serum NMDA Receptor Antibodies and Response to Antipsychotic Treatment in First-Episode Psychosis". Biological Psychiatry (2020): https://doi.org/10.1016%2Fj.biopsych.2020.11.014.
    10.1016/j.biopsych.2020.11.014
  9. Coutinho, Ester. "Clinical, cognitive and neuroanatomical associations of serum NMDAR autoantibodies in people at clinical high risk for psychosis.". Molecular psychiatry (2020): https://doi.org/10.1038/s41380-020-00899-w.
    10.1038/s41380-020-00899-w
  10. L. L. Gibson; A. McKeever; E. Coutinho; C. Finke; T. A. Pollak. "Cognitive impact of neuronal antibodies: encephalitis and beyond". Translational Psychiatry 10 1 (2020): https://doi.org/10.1038%2Fs41398-020-00989-x.
    10.1038/s41398-020-00989-x
  11. Katya Marks; Ester Coutinho; Angela Vincent. "Maternal-Autoantibody-Related (MAR) Autism: Identifying Neuronal Antigens and Approaching Prospects for Intervention". Journal of Clinical Medicine 9 8 (2020): 2564-2564. https://doi.org/10.3390%2Fjcm9082564.
    10.3390/jcm9082564
  12. Liam Carroll; Sven Braeutigam; John M. Dawes; Zeljka Krsnik; Ivica Kostovic; Ester Coutinho; Jennifer M. Dewing; et al. "Autism Spectrum Disorders: Multiple Routes to, and Multiple Consequences of, Abnormal Synaptic Function and Connectivity". The Neuroscientist 27 1 (2020): 10-29. https://doi.org/10.1177%2F1073858420921378.
    10.1177/1073858420921378
  13. Baglioni, V.; Coutinho, E.; Menassa, D.A.; Giannoccaro, M.P.; Jacobson, L.; Buttiglione, M.; Petruzzelli, O.; Cardona, F.; Vincent, A.. "Antibodies to neuronal surface proteins in Tourette Syndrome: Lack of evidence in a European paediatric cohort". Brain, Behavior, and Immunity 81 (2019): 665-669. http://dx.doi.org/10.1016/j.bbi.2019.08.008.
    10.1016/j.bbi.2019.08.008
  14. Giannoccaro, Maria Pia; Menassa, David A; Jacobson, Leslie; Coutinho, Ester; Prota, Gennaro; Lang, Bethan; Leite, M Isabel; et al. "Behaviour and neuropathology in mice injected with human contactin-associated protein 2 antibodies". Brain 142 7 (2019): 2000-2012. http://dx.doi.org/10.1093/brain/awz119.
    10.1093/brain/awz119
  15. Fernandes, Dominique; Santos, Sandra D; Coutinho, Ester; Whitt, Jessica L; Beltrão, Nuno; Rondão, Tiago; Leite, M Isabel; et al. "Disrupted AMPA Receptor Function upon Genetic- or Antibody-Mediated Loss of Autism-Associated CASPR2". Cerebral Cortex 29 12 (2019): 4919-4931. http://dx.doi.org/10.1093/cercor/bhz032.
    10.1093/cercor/bhz032
  16. Dawes, John M.; Weir, Greg A.; Middleton, Steven J.; Patel, Ryan; Chisholm, Kim I.; Pettingill, Philippa; Peck, Liam J.; et al. "Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability". Neuron 97 4 (2018): 806-822.e10. http://dx.doi.org/10.1016/j.neuron.2018.01.033.
    10.1016/j.neuron.2018.01.033
  17. Ester Coutinho; Leslie Jacobson; Marianne Giørtz Pedersen; Michael Eriksen Benros; Bent Nørgaard-Pedersen; Preben Bo Mortensen; Paul J Harrison; Angela Vincent. "CASPR2 autoantibodies are raised during pregnancy in mothers of children with mental retardation and disorders of psychological development but not autism". Journal of Neurology, Neurosurgery & Psychiatry 88 9 (2017): 718-721. https://doi.org/10.1136%2Fjnnp-2016-315251.
    10.1136/jnnp-2016-315251
  18. Ernestina Santos; Ester Coutinho; Ana Martins da Silva; António Marinho; Carlos Vasconcelos; Ricardo Taipa; Manuel Melo Pires; et al. "Inflammatory myopathy associated with myasthenia gravis with and without thymic pathology: Report of four cases and literature review". Autoimmunity Reviews 16 6 (2017): 644-649. https://doi.org/10.1016%2Fj.autrev.2017.04.009.
    10.1016/j.autrev.2017.04.009
  19. Ester Coutinho; David Menassa; Leslie Jacobson; Steven West; Joana Domingos; Teresa Moloney; Marianne G Pedersen; et al. "Maternal CASPR2 antibodies and neurodevelopmental disorders in the offspring: epidemiological findings and an animal model". The Lancet 389 (2017): S18-S18. https://doi.org/10.1016%2Fs0140-6736%2817%2930414-2.
    10.1016/s0140-6736(17)30414-2
  20. Coutinho, E.; Menassa, D.A.; Jacobson, L.; West, S.J.; Domingos, J.; Moloney, T.C.; Lang, B.; et al. "Persistent microglial activation and synaptic loss with behavioral abnormalities in mouse offspring exposed to CASPR2-antibodies in utero". Acta Neuropathologica 134 4 (2017): 567-583. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026451577&partnerID=MN8TOARS.
    10.1007/s00401-017-1751-5
  21. Gaughran, F.; Lally, J.; Beck, K.; McCormack, R.; Gardner-Sood, P.; Coutinho, E.; Jacobson, L.; et al. "Brain-relevant antibodies in first-episode psychosis: a matched case–control study". Psychological Medicine (2017): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-85030860781&partnerID=MN8TOARS.
    10.1017/S0033291717002689
  22. Santos, E.; Coutinho, E.; Moreira, I.; Silva, A.M.; Lopes, D.; Costa, H.; Silveira, F.; et al. "Epidemiology of myasthenia gravis in Northern Portugal: Frequency estimates and clinical epidemiological distribution of cases". Muscle and Nerve 54 3 (2016): 413-421. http://www.scopus.com/inward/record.url?eid=2-s2.0-84982179134&partnerID=MN8TOARS.
    10.1002/mus.25068
  23. Nour, M.M.; Nakashima, I.; Coutinho, E.; Woodhall, M.; Sousa, F.; Revis, J.; Takai, Y.; et al. "Pregnancy outcomes in aquaporin-4-positive neuromyelitis optica spectrum disorder". Neurology 86 1 (2016): 79-87. http://www.scopus.com/inward/record.url?eid=2-s2.0-84952360960&partnerID=MN8TOARS.
    10.1212/WNL.0000000000002208
  24. Monica Marta; Ernestina Santos; Ester Coutinho; Ana Martins Silva; João Correia; Carlos Vasconcelos; Gavin Giovannoni. "The role of infections in Behçet disease and neuro-Behçet syndrome". Autoimmunity Reviews 14 7 (2015): 609-615. https://doi.org/10.1016%2Fj.autrev.2015.02.009.
    10.1016/j.autrev.2015.02.009
  25. Ana Martins Da Silva; Sara Cavaco; Inês Moreira; Andreia Bettencourt; Ernestina Santos; Cláudia Pinto; Alexandra Gonçalves; et al. "Cognitive reserve in multiple sclerosis: Protective effects of education". Multiple Sclerosis Journal 21 10 (2015): 1312-1321. https://doi.org/10.1177%2F1352458515581874.
    10.1177/1352458515581874
  26. Ernestina Santos; Isabel Moreira; Ester Coutinho; Guilherme Gonçalves; Carlos Lopes; José Lopes Lima; M. Isabel Leite. "Congenital myasthenic syndrome due to mutation in CHRNE gene with clinical worsening and thymic hyperplasia attributed to association with autoimmune-myasthenia gravis". Neuromuscular Disorders 25 12 (2015): 928-931. https://doi.org/10.1016%2Fj.nmd.2015.08.001.
    10.1016/j.nmd.2015.08.001
  27. Alexander Carvajal-González; M. Isabel Leite; Patrick Waters; Mark Woodhall; Ester Coutinho; Bettina Balint; Bethan Lang; et al. "Glycine receptor antibodies in PERM and related syndromes: characteristics, clinical features and outcomes". Brain 137 8 (2014): 2178-2192. https://doi.org/10.1093%2Fbrain%2Fawu142.
    10.1093/brain/awu142
  28. Belinda Lennox; Michael S. Zandi; Julia B. Deakin; Alasdair Coles; Linda Scoriels; Peter Jones; Ester Coutinho; Angela Vincent. "NMDA RECEPTOR ANTIBODIES IN FIRST EPISODE PSYCHOSIS: PREVALENCE AND CLINICAL PHENOTYPE". Schizophrenia Research 153 (2014): S35-S35. https://doi.org/10.1016%2Fs0920-9964%2814%2970116-1.
    10.1016/s0920-9964(14)70116-1
  29. Ester Coutinho; Paul Harrison; Angela Vincent. "Do Neuronal Autoantibodies Cause Psychosis? A Neuroimmunological Perspective". Biological Psychiatry 75 4 (2014): 269-275. https://doi.org/10.1016%2Fj.biopsych.2013.07.040.
    10.1016/j.biopsych.2013.07.040
  30. Carvajal-González, A.; Isabel Leite, M.; Waters, P.; Woodhall, M.; Coutinho, E.; Balint, B.; Lang, B.; et al. "Erratum: Glycine receptor antibodies in PERM and related syndromes: Characteristics, clinical features and outcomes (Brain (2014) 137 (2178-2192) DOI:10.1093/brain/awu142)". Brain 137 12 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84922367480&partnerID=MN8TOARS.
    10.1093/brain/awu274
  31. Joana Damásio; M. Isabel Leite; Ester Coutinho; Patrick Waters; Mark Woodhall; Manuela A. Santos; Inês Carrilho; Angela Vincent. "Progressive Encephalomyelitis With Rigidity and Myoclonus: The First Pediatric Case With Glycine Receptor Antibodies". JAMA Neurology 70 4 (2013): 498-498. https://doi.org/10.1001%2Fjamaneurol.2013.1872.
    10.1001/jamaneurol.2013.1872
  32. Kim, W.; Kim, S.-H.; Nakashima, I.; Takai, Y.; Fujihara, K.; Leite, M.I.; Kitley, J.; et al. "Influence of pregnancy on neuromyelitis optica spectrum disorder". Neurology 78 16 (2012): 1264-1267. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860708188&partnerID=MN8TOARS.
    10.1212/WNL.0b013e318250d812
  33. Cavaco, S.; Martins Da Silva, A.; Santos, E.; Coutinho, E.; Marinho, A.; Moreira, I.; Gonçalves, A.; et al. "Are cognitive and olfactory dysfunctions in neuropsychiatric lupus erythematosus dependent on anxiety or depression?". Journal of Rheumatology 39 4 (2012): 770-776. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859463832&partnerID=MN8TOARS.
    10.3899/jrheum.110574
  34. Leite, M.I.; Coutinho, E.; Lana-Peixoto, M.; Apostolos, S.; Waters, P.; Sato, D.; Melamud, L.; et al. "Myasthenia gravis and neuromyelitis optica spectrum disorder: A multicenter study of 16 patients". Neurology 78 20 (2012): 1601-1607. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863580450&partnerID=MN8TOARS.
    10.1212/WNL.0b013e31825644ff
  35. Ana Martins Silva; Ernestina Santos; Inês Moreira; Andreia Bettencourt; Ester Coutinho; Alexandra Gonçalves; Claudia Pinto; Xavier Montalban; Sara Cavaco. "Olfactory dysfunction in multiple sclerosis: association with secondary progression". Multiple Sclerosis Journal 18 5 (2011): 616-621. https://doi.org/10.1177%2F1352458511427156.
    10.1177/1352458511427156
  36. Ester Coutinho; Ana M Silva; Cláudia Freitas; Ernestina Santos. "Graves' disease presenting as pseudotumor cerebri: a case report". Journal of Medical Case Reports 5 1 (2011): https://doi.org/10.1186%2F1752-1947-5-68.
    10.1186/1752-1947-5-68
  37. Carlos Almeida; Ester Coutinho; Daniela Moreira; Ernestina Santos; José Aguiar; Almeida, C.; Coutinho, E.; et al. "Myasthenia gravis and pregnancy: anaesthetic management – a series of cases". European Journal of Anaesthesiology 27 11 (2010): 985-990. https://doi.org/10.1097%2Feja.0b013e32833e263f.
    10.1097/eja.0b013e32833e263f
  38. Ester Coutinho; José Pedro Pereira; Daniel Dias; Sara Cavaco; Cláudia Pinto; Rui Carvalho; Marina Magalhães. "Tremor and white matter lesions in Klinefelter syndrome". Movement Disorders 25 12 (2010): 1993-1994. https://doi.org/10.1002%2Fmds.23149.
    10.1002/mds.23149
  39. Cavaco, Sara; Da Silva, Ana Martins; Pinto, Pedro; Coutinho, Estér; Santos, Ernestina; Bettencourt, Andreia; Pinto, Cláudia; et al. "Cognitive Functioning in Behçet's Disease". Annals of the New York Academy of Sciences 1173 1 (2009): 217-226. http://dx.doi.org/10.1111/j.1749-6632.2009.04670.x.
    10.1111/j.1749-6632.2009.04670.x
  40. Coutinho, E.; Pereira-Monteiro, J.. "'Bad trips': Airplane headache not just in airplanes?". Cephalalgia 28 9 (2008): 986-987. http://www.scopus.com/inward/record.url?eid=2-s2.0-49649112646&partnerID=MN8TOARS.
    10.1111/j.1468-2982.2008.01632.x
Capítulo de livro
  1. Pollak, Thomas A.; Coutinho, Ester; Palmer-Cooper, Emma; Vincent, Angela. "Inflammatory and autoimmune disorders in neuropsychiatry". In Oxford Textbook of Neuropsychiatry, 245-258. Oxford University Press, 2020.
    10.1093/med/9780198757139.003.0022
  2. Coutinho, Ester; Vincent, Angela. "Autoimmunity in neuropsychiatric disorders". In Handbook of Clinical Neurology, 269-282. Elsevier, 2016.
    10.1016/b978-0-444-63432-0.00015-3
  3. Coutinho, E.; Vincent, A.; Ester Coutinho; Angela Vincent. "Central Nervous System Neuronal Surface Antibodies". In Handbook of Clinical Neurology. 2013.
    10.1016/B978-0-444-56378-1.00070-8
Poster em conferência
  1. Serrenho, Débora; Fernandes, Dominique; Vasconcelos, Ana; Santos, Sandra; Cortes, Luisa; Coutinho, Ester; Carvalho, Ana Luisa. "Human anti-CASPR2 autoantibodies impact synaptic transmission and neuronal excitability (to be presented)". Trabalho apresentado em 8th European Synapse Meeting, 2022.
  2. Oliveira, Ana Rafaela; Cammarata, G; Cardoso, AM; Seabra, C; Guedes, J; Cardoso, AL; Fernandes, Dominique; et al. "Autism associated CASPR2 auto-immune antibodies modify the developmental trajectory and network activity in human brain organoids". Trabalho apresentado em 13th FENS Forum of Neuroscience, 2022.
  3. Vasconcelos, Ana; Fernandes, Dominique; Santos, Sandra Manuela Domingues dos; Coutinho, Ester; Carvalho, Ana Luisa. "Concentration-dependent effects elicited by CASPR2 autoantibodies in the regulation of AMPA receptor trafficking and synaptic plasticity". Trabalho apresentado em Encephalitis Society 2021, 2021.
  4. Vasconcelos, Ana; Fernandes, Dominique; Santos, Sandra Manuela Domingues dos; Coutinho, Ester; Whitt, Jessica L; Lee, Hey-Kyoung; Carvalho, Ana Luisa. "CASPR2 autoantibodies elicit concentration-dependent perturbations in the regulation of AMPA receptor trafficking and synaptic plasticity.". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  5. Oliveira, Ana Rafaela; Seabra, Catarina; Guedes, Joana; Cammarata, Giuseppe; Cardoso, Ana Maria; Fernandes, Dominique; Coutinho, Ester; et al. "Uncovering the neurodevelopmental consequences of anti-CASPR2 antibody exposure in 3D brain organoids". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  6. Oliveira, Ana Rafaela; Seabra, Catarina M.; Guedes, Joana Ribeiro; Cammarata, G.; Fernandes, Dominique; Coutinho, Ester; Carvalho, Ana Luisa; Ferreira, Lino; Peça, João. "Uncovering the role of immune response in ASD: Neurodevelopmental consequences of anti-CASPR2 antibodies exposure in 3D brain organoids". Trabalho apresentado em EMBL Symposia "Organoids: Modelling Organ Development and Disease in 3D Culture - Virtual", 2020.
  7. Fernandes, Dominique; Vasconcelos, Ana M.; Santos, Sandra; Coutinho, Ester; Whitt, Jessica L; Beltrão, Nuno; Rondão, Tiago; et al. "Disrupted AMPA receptor function and synaptic plasticity upon genetic- or antibody-mediated loss of autism-related CASPR2". Trabalho apresentado em CIBB Annual Meeting, 2019.
  8. Fernandes, Dominique; Vasconcelos, Ana; Santos, Sandra; Coutinho, Ester; Whitt, Jessica L; Beltrão, Nuno; Rondão, Tiago; et al. "CASPR2 autoantibodies disrupt AMPA receptor function". Trabalho apresentado em Encephalitis Conference 2019, 2019.
  9. Fernandes, Dominique; Santos, Sandra; Whitt, Jessica L; Coutinho, Ester; Leite, M. Isabel; Buckley, Camilla; Lee, Hey-Kyoung; Carvalho, Ana Luisa. "Autism-associated Caspr2 regulates synaptic AMPA receptors in the context of homeostatic synaptic plasticity". Trabalho apresentado em 2017 Excitatory Synapses & Brain Function Gordon Research Conference., 2017.
  10. Fernandes, Dominique; Santos, Sandra; Whitt, Jessica L; Coutinho, Ester; Leite, M. Isabel; Buckley, Camilla; Lee, Hey-Kyoung; Carvalho, Ana Luísa. "Contactin-associated proteins 1 and 2 (Caspr1 & Caspr2) - unexpected key players in the regulation of homeostatic synaptic scaling". Trabalho apresentado em 2016 Regional meeting of the International Society for Neurochemistry ¿ Synaptic Function and Dysfunction in Brain Diseases, 2016.
  11. Fernandes, Dominique; Santos, Sandra; Whitt, Jessica L; Coutinho, Ester; Leite, M. Isabel; Buckley, Camilla; Lee, Hey-Kyoung; Carvalho, Ana Luísa. "Homeostatic scaling of synaptic AMPA receptors: the unexpected role of Contactin-associated proteins 1 and 2 (Caspr1 & Caspr2)". Trabalho apresentado em Integrating Hebbian and Homeostatic Plasticity, 2016.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2021/07/07 The patients who changed the field of autoimmune neurology SINNAPS Seminar
(Reino Unido)
2021/03/19 Maternal antibodies and neurodevelopment disorders Dutch Autisme Conference
(Países Baixos)
2020/10/17 Maternal antibodies and neurodevelopment disorders IV Congresso labirinto do autismo
(Brasil)
2020/02/15 Maternal antibodies in neurodevelopmental diseases X Congresso Nacional de Patologia Clinica
Sociedade Portuguesa de Patologia Clinica (Porto, Portugal)
2019/09/10 Autoimmune encephalitis and Graus criteria Mental Health and Neuroimmunology conference
Encephalitis Society (Kent, Reino Unido)
2019/06/28 The influence of maternal antibodies on ASD and neurodevelopment 1st International Congress on Autism Spectrum Disorders
Associação Caminho Azul (Rio de Janeiro, Brasil)
2018/11/30 Cell surface neuronal antibodies and their roles in neurological diseases The A-Z of MS
King's College Hospital (London, Reino Unido)
2018/05/17 Cell surface neuronal antibodies and their roles in neurological diseases 11th Internation Conference on Autoimmunity
(Lisbon, Portugal)
2017/09/15 CNS Antibody-Mediated Diseases. 5th Keele course on CNS inflammation
Keele University (Staffordshire, Reino Unido)
2017/03/16 Maternal antibodies and neurodevelopmental disorders in the offspring Inaugural Oxford Neurodevelopment Consortium
Oxford Neurodevelopment Consortium (Oxford, Reino Unido)
2017/01/04 Maternal antibodies in neurodevelopmental disorders
Center for Neuroscience and cell biology & Institute for biomedical imaging and life sciences (Coimbra, Portugal)
2016/10/18 Maternal antibodies in neurodevelopmental disorders
Institute of Psychiatry, Psychology & Neuroscience (London, Reino Unido)
2016/04/04 Antibodies to Neuronal Cell Surface Antigens in Psychiatric Disease. 5th Biennial Schizophrenia International Research Society conference
(Florence, Itália)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2023/07 - Atual Understanding the role of maternal IgG antibodies in brain development
Orientador
Mestrado em Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra, Portugal
2021/12/10 - Atual Prevalence and determinants of fatigue in longcovid and multiple sclerosis
Orientador
MSc in Clinical Neuropsychiatry (Mestrado)
2021/10/10 - Atual Characterisation of pain syndromes in patients with longcovid
Orientador
MSc in Clinical Neuropsychiatry (Mestrado)
2019 - 2019 Antibody-mediated microglial activation in neurodevelopmental and neuropsychiatric disorders
Coorientador
Clinical Neuropsychiatry MSc (Mestrado)
Institute of Psychiatry Psychology and Neuroscience Department of Basic and Clinical Neuroscience, Reino Unido
2017 - 2017 Tourette syndrome and autoantibodies
Orientador
University of Oxford Nuffield Department of Clinical Neurosciences, Reino Unido

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2023 the role of IgLON5 in neuronal function
Vogal
Beatriz Ribeiro (Doutoramento)
Universidade de Coimbra, Portugal
2022/07 MODULATION OF GABAERGIC SYNAPSES BY AUTOANTIBODIES FROM EPILEPTIC PATIENTS
Arguente principal
Catarina Daniela Gonçalves Rodrigues (Mestrado)
Universidade de Coimbra, Portugal
2022 Information design as a vector in science communication: A co-design approach involving Autoimmune Encephalitis patients, their families, and scientists
Vogal
Ana Maria da Graça Fernandes Vasconcelos (Doutoramento)
Universidade de Coimbra, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2023/02 - Atual The Federation of European Neuroscience Societies Regional Meeting The Federation of European Neuroscience Societies

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2022/06/01 - Atual Module sub-coordinator: Thinking and doing II; Medical course; Universidade Catolica, Lisbon Medicine (Mestrado integrado) Universidade Católica Portuguesa, Portugal
2022/03/02 - Atual Module coordinator: Thinking and doing I Medicine (Licenciatura) Universidade Católica Portuguesa, Portugal
2021/06/01 - Atual Module leader - Scientific Foundations of Neuropsychiatry, MSc in Clinical Neuropsychiatry, KCL MSc in Clinical Neuropsychiatry (Master) King's College London - Denmark Hill Campus, Reino Unido

Tutoria

Tópico Nome do aluno
2014 - 2014 Antibody-mediated neurological diseases: clinical and laboratorial training in peripheral and central nervous system disorders Dr Joana Domingos
Distinções

Prémio

2017 Pre-Doctoral Plenary Competition joint first prize
Academy of Medical Sciences, Reino Unido
2014 Oxion day poster prize
Oxion Programme, Reino Unido
2010 Young Researchers Grant - 26th ECTRIMS conference
European Committee for Treatment and Research in Multiple Sclerosis, Suiça