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Carlos Guimarães. Completed the Mestrado integrado in Bioengineering in 2017/07 by Universidade do Porto Faculdade de Engenharia, Doutoramento in Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais in 2022/02/18 by Stanford University School of Medicine and Doutoramento in Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais in 2022/02/18 by Universidade do Minho. Is Contracted Researcher in Universidade do Minho. Published 12 articles in journals. Has 1 section(s) of books. Has 1 patent(s) registered. Organized 3 event(s). Participated in 1 event(s). Has received 11 awards and/or honors. Participates and/or participated as Co-Principal Investigator (Co-PI) in 1 project(s), PhD Student Fellow in 3 project(s), Principal investigator in 1 project(s) and Researcher in 3 project(s). Works in the area(s) of Engineering and Technology with emphasis on Materials Engineering, Natural sciences with emphasis on Biological Sciences with emphasis on Cell Biology, Medical and Health Sciences with emphasis on Medical Biotechnology with emphasis on Biomaterials and Medical and Health Sciences with emphasis on Medical Biotechnology with emphasis on Health-Related Biotechnology. In their professional activities interacted with 29 collaborator(s) co-authorship of scientific papers. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Tissue engineering; Hydrogel microfibers; 3D biological models; Cancer models; Vascular fibers; Bioengineering; Organ on a chip; Self-assembly; Externally driven assembly; Personalized medicine; Point of Care, ; Detection; Biofabrication; 3D Cancer Models; Microfluidics; Hydrogels; .
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Identificação

Identificação pessoal

Nome completo
Carlos Guimarães

Nomes de citação

  • Guimarães, Carlos F.

Identificadores de autor

Ciência ID
A116-C6D1-2109
ORCID iD
0000-0001-8235-0597

Telefones

Telemóvel
  • 912325069 (Pessoal)

Websites

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Engenharia dos Materiais
  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biotecnologia Aplicada à Saúde

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador independente (B1)
Francês Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2017/09/04 - 2022/02/18
Concluído
 Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento)
Especialização em Sem especialidade
Universidade do Minho, Portugal

Stanford University School of Medicine, Estados Unidos
"Microfluidic Hydrogel Biofabrication for High-Throughput Screening, Modeling, and Quantifying 3D Biological Phenomena" (TESE/DISSERTAÇÃO)
 Muito Bom (Maximum Grade)
2012/09 - 2017/07
Concluído
 Bioengineering (Mestrado integrado)
Especialização em Biotechnology
Universidade do Porto Faculdade de Engenharia, Portugal
"Cancer-associated Fibroblasts and tumor-associated macrophages: Exploring their mutual regulation" (TESE/DISSERTAÇÃO)
 18
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2023/08/31 - Atual Investigador Contratado (Investigação) Universidade do Minho, Portugal
Biomaterials Biodegradables and Biomimetics, Portugal
2022/02/19 - 2023/08/30 Pós-doutorado (Investigação) Biomaterials Biodegradables and Biomimetics, Portugal
Biomaterials Biodegradables and Biomimetics, Portugal
2020/03/01 - 2021/02/28 Investigador visitante (Investigação) Stanford University School of Medicine, Estados Unidos
Stanford University Department of Radiology, Estados Unidos
2016/02/15 - 2016/07/15 Estagiário de Investigação (Investigação) Rijksuniversiteit Groningen, Países Baixos

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2017/09/01 - 2022/02/18 PhD Student Universidade do Minho, Portugal
Biomaterials Biodegradables and Biomimetics, Portugal
(...)
2016/10/01 - 2017/07/15 MSc Student Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Projetos

Bolsa

Designação Financiadores
2021/10/01 - 2022/02/28 FCT Exceptional COVID19 Scholarship
COVID/BD/152016/2021
Bolseiro de Doutoramento
Biomaterials Biodegradables and Biomimetics, Portugal

Stanford University Department of Radiology, Estados Unidos

Stanford University School of Medicine, Estados Unidos
Concluído
2017/09/04 - 2022/02/20 FCT PhD Scholarship
PD/BD/135253/2017
Bolseiro de Doutoramento
Biomaterials Biodegradables and Biomimetics, Portugal

Stanford University School of Medicine, Estados Unidos
Fundação para a Ciência e a Tecnologia
Concluído
2020/03/01 - 2021/02/28 R&D@PhD Scholarship
Proj. 13/2020
Investigador
Stanford University Department of Radiology, Estados Unidos

Biomaterials Biodegradables and Biomimetics, Portugal
Fundação Luso-Americana
Concluído

Projeto

Designação Financiadores
2023/08/16 - 2029/08/15 Living Hydrogel Optical Fibers: The Digitalization of 3D Biology
2022.05711.CEECIND/CP1718/CT0012
10.54499/2022.05711.CEECIND/CP1718/CT0012
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2023/03/01 - 2026/02/28 Cancer Optical fibers: pre-Metastatic Engineered Tissues
2022.05737.PTDC
10.54499/2022.05737.PTDC
Co-Investigador Responsável (Co-IR)
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2020/08/15 - 2021/08/14 Swab-Couplable Hydrogel Optical Fibers for COVID19 in situ diagnostics
RPH 13.2
Investigador
Stanford University, Estados Unidos
 Stanford RISE
Concluído
2021/01/01 - 2021/05/01 Swab-Couplable Hydrogel Optical Fibers for in situ diagnostics of SARS-CoV-2 and other respiratory viruses
2021/swab-couplable-hydrogel
Investigador
Stanford University Department of Radiology, Estados Unidos
 Stanford PHIND
Concluído
2017 - 2019 ERC Advanced Grant ComplexiTE
Grant agreement ID: 321266
Bolseiro de Doutoramento
Biomaterials Biodegradables and Biomimetics, Portugal
 European Research Council
Concluído
Produções

Publicações

Artigo em jornal
  1. "Living optical fibers expand the use of photonics for bioengineering", Nanowerk, 2021, https://www.nanowerk.com/spotlight/spotid=58895.php.
Artigo em revista
  1. Guimarães, Carlos F; Liu, Shiqin; Wang, Jie; Purcell, Emma; Ozedirne, Tugba; Ren, Tanchen; Aslan, Merve; et al. "Co-axial hydrogel spinning for facile biofabrication of prostate cancer-like 3D models". Biofabrication (2024): http://dx.doi.org/10.1088/1758-5090/ad2535.
    10.1088/1758-5090/ad2535
  2. "Microfluidic mixing system for precise PLGA-PEG nanoparticles size control". Nanomedicine: Nanotechnology, Biology and Medicine (2021): 102482-102482. http://dx.doi.org/10.1016/j.nano.2021.102482.
    10.1016/j.nano.2021.102482
  3. Guimarães, Carlos F.. "Engineering Polysaccharide-Based Hydrogel Photonic Constructs: From Multiscale Detection to the Biofabrication of Living Optical Fibers". Advanced Materials (2021): 2105361-2105361. http://dx.doi.org/10.1002/adma.202105361.
    10.1002/adma.202105361
  4. Guimarães, Carlos F.. "Wearable Collector for Noninvasive Sampling of SARS-CoV-2 from Exhaled Breath for Rapid Detection". ACS Applied Materials & Interfaces 13 35 (2021): 41445-41453. http://dx.doi.org/10.1021/acsami.1c09309.
    10.1021/acsami.1c09309
  5. Guimarães, Carlos F.. "Engineering Hydrogel-Based Biomedical Photonics: Design, Fabrication, and Applications". Advanced Materials (2021): 2006582-2006582. http://dx.doi.org/10.1002/adma.202006582.
    10.1002/adma.202006582
  6. Guimarães, Carlos F.. "3D flow-focusing microfluidic biofabrication: One-chip-fits-all hydrogel fiber architectures". Applied Materials Today 23 (2021): 101013-101013. https://www.sciencedirect.com/science/article/pii/S2352940721000780.
    https://doi.org/10.1016/j.apmt.2021.101013
  7. Guimarães, Carlos F.. "Emerging biofabrication approaches for gastrointestinal organoids towards patient specific cancer models". Cancer Letters 504 (2021): 116-124. https://www.sciencedirect.com/science/article/pii/S0304383521000471.
    https://doi.org/10.1016/j.canlet.2021.01.023
  8. Guimarães, Carlos F.. "High-throughput fabrication of cell-laden 3D biomaterial gradients". Materials Horizons (2020): http://dx.doi.org/10.1039/d0mh00818d.
    10.1039/d0mh00818d
  9. Guimarães, Carlos F.; Gasperini, Luca; Marques, Alexandra P.; Reis, Rui L.. "The stiffness of living tissues and its implications for tissue engineering". Nature Reviews Materials (2020): http://dx.doi.org/10.1038/s41578-019-0169-1.
    10.1038/s41578-019-0169-1
  10. Guimarães, Carlos. "Development of a Novel Orthogonal Double Gradient for High-Throughput Screening of Mesenchymal Stem Cells--Materials Interaction". Advanced Materials Interfaces (2018): 1800504-1800504.
    10.1002/admi.201800504
  11. Guimarães, Carlos. "KRAS Oncogenic Signaling Extends beyond Cancer Cells to Orchestrate the Microenvironment". Cancer Research (2017): http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-5472.CAN-17-2084.
    10.1158/0008-5472.CAN-17-2084
  12. Guimarães, Carlos. "Screening Platform for Cell Contact Guidance Based on Inorganic Biomaterial Micro/nanotopographical Gradients.". ACS applied materials & interfaces (2017): http://europepmc.org/abstract/med/28825457.
    10.1021/acsami.7b08237
Capítulo de livro
  1. Guimarães, Carlos F.; Gasperini, Luca; Reis, Rui L.. Autor correspondente: Guimarães, Carlos F.. "Microfluidic-Driven Biofabrication and the Engineering of Cancer-Like Microenvironments". In Microfluidics and Biosensors in Cancer Research. Springer Nature, 2022.
    No prelo
Poster em conferência
  1. Guimarães, Carlos F.; Luca Gasperini; Alexandra P. Marques; Rui L. Reis. "Microfluidic Fabrication of Cell-Laden 3D Biomaterial Gradients". Trabalho apresentado em TermStem/Achilles 2019, 2019.
  2. Guimarães, Carlos F.; Luca Gasperini; Alexandra P. Marques; Rui L. Reis. "3D Microfluidic Gradients for Detecting Best-Fit Biomaterial Formulations towards Cellular Stimulation.". Trabalho apresentado em Forecast/Achilles 2019, 2019.
  3. Guimarães, Carlos F.; Luca Gasperini; Alexandra P. Marques; Rui L. Reis. "High-Throughput Discovery of Stem Cell Responses to 3D Material Gradients.". Trabalho apresentado em 1st Discoveries Forum on Regenerative and Precision Medicine, 2019.
  4. Guimarães, Carlos F.; Luca Gasperini; Raquel S. Ribeiro; Andreia F. Carvalho; Alexandra P. Marques; Rui L. Reis. "Microfluidic fabrication of 3D biomaterial libraries towards high-throughput quantitative stem cell responses screening.". Trabalho apresentado em Chem2Nature Final Conference, 2018.
  5. Guimarães, Carlos F.; Patrícia Dias Carvalho; Flávia Castro; Flávia Martins; Maria José Oliveira; Sérgia Velho. "Fibroblasts as stromal modulators of macrophage polarization and cancer cell invasion.". Trabalho apresentado em Symposium on immunomodulation in cancer and regeneration, 2017.
Tese / Dissertação
  1. "Microfluidic Hydrogel Biofabrication For High-Throughput Screening, Modelling and Quantifying 3D Biological Phenomena". Doutoramento, Biomaterials Biodegradables and Biomimetics, 2021. http://repositorium.sdum.uminho.pt/handle/1822/76111.
  2. Guimarães, Carlos F.. "Cancer-associated fibroblasts in cancer cell metastasis and tumor-associated macrophage polarization". Mestrado, Universidade do Porto Faculdade de Engenharia, 2017.

Propriedade Intelectual

Patente
  1. Guimarães, Carlos F.; Gasperini, Luca; Alexandra P. Marques; Reis, Rui L.. 2023. "Multicompartement hydrogel fibre their preparation and uses thereof".
    Pendente
Pedido provisório de patente
  1. 2021. "Hydrogel Optical Fibers and Their Application and Use".
    Divulgado

Outros

Invenção
  1. Living Optical Fibers. 2021. Guimarães, Carlos F.; Reis, Rui L.; Utkan Demirci.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/01 The Engineering of Living Optical Fibers XIII Congress of the Order of the Engineers
Ordem dos Engenheiros (Porto, Portugal)
2023/09 Microfluidic-Driven Hydrogel Biofabrication for in vitro Modelling of Healthy and Diseased 3D Biological Environments Health-Unorte Conference
Health Unorte Project (Guimaraes, Portugal)
2023/06 Microfluidic-Driven Hydrogel Biofabrication and the Engineering of Living Cancer Optical Fibers X Biotech Health Symposium
Biotech Health Doctoral Program (Porto, Portugal)
2023/02 Cells, Biomaterials and Microfluidics – from tissue Engineering to the Biofabrication of Living Optical Fibers XVIII Symposium of Biomedical Engineering
Biomedical Engineering Course, University of Minho (Braga, Portugal)
2022/07 Microfluidic-Enabled Biofabrication of 3D Hydrogel Architectures and Light-Driven Digitalization of Dynamic Cancer Responses TERMIS AM Chapter Conference
TERMIS (Toronto, Canadá)
2022/04 Microfluidic-Driven Hydrogel Tissue Engineering for Modelling and Digitalizing Complex Biological Phenomena Society for Biomaterials, 2022 Meeting
Society for Biomaterials (Baltimore, Estados Unidos)
2022/03/26 Bending Cells and Materials to a Bioengineer¿'s Will: Fabricating Living Tissues, Engineering 3D Cancer Models, and Fighting COVID19. Symposium of Bioengineering
Faculty of Engineering of the University of Porto (Porto, Portugal)
2022/03/17 Microfluidic-Driven Hydrogel Biofabrication of 3D Biological Models and Living Optical Fibers INM Kolloqium
Leibniz Institute for New Materials (Leibniz, Alemanha)
2021/10 Hydrogel Bioarchitectures for Modelling and Digitalizing 3D Cancer Dynamics toward the Discovery of Functional Drug Thresholds Final FoReCaST Conference
3B's Research Group (Porto, Portugal)
2021/09 Microfluidic-Driven Hydrogel Biofabrication for Engineering Living Microtissue Architectures 31st European Conference on Biomaterials
European Society for Biomaterials (ESB) (Porto, Portugal)
2020/10 How to Publish High-Impact Review Articles
Nanophotonics & Biosensors Bangladesh Chapter (Bangladesh)
2020/02 Microfluidics as a tool for high-throughput biomaterial screening and complex biofabrication
Iberian Nanotechnology Laboratory (INL) (Braga, Portugal)
2019/05/04 Microfluidic fabrication of 3D biomaterial libraries for high-throughput screening stem cell responses TERMIS EU 2019
Tissue Engineering and Regenerative Medicine International Society (Rhodes, Grécia)
2018/11/05 From low to high-throughput: Development of a 3D Gellan Gum gradient to screen the effect of hydrogel mechanics on ASC commitment. Chem2Nature Summer School
3B's Research Group (Porto , Portugal)
2018/09/05 From low- to high-throughput: Microfluidic fabrication of novel 3D biomaterial libraries for screening cell responses 29th European Conference on Biomaterials
European Society for Biomaterials (Maastricht, Países Baixos)

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2017 - 2019 Gene2Skin International Twinning Conferences (2017)
Conferência (Membro da Comissão Organizadora)
 Biomaterials Biodegradables and Biomimetics, Portugal
2018 - 2018 Scientific Pictures Art Contest (2018 - 2018)
Concurso (Coorganizador)
 Biomaterials Biodegradables and Biomimetics, Portugal
2018 - 2018 Guimarães City Science Exposition Open Store (2018 - 2018)
Exposição (Presidente da Comissão Organizadora)
 Biomaterials Biodegradables and Biomimetics, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2018/09 - Atual Participation in the IV Quantitative Fluorescence Microscopy Course
Oficina (workshop)
Universidade de Coimbra, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2021 - Atual International Journal of Nanomedicine (1178-2013) Dove Press
2020 - Atual Michrochimica Acta (1436-5073) Springer

Comissão de avaliação

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2019/02/22 - 2019/02/23 Invited as Reviewer of the 6th IEEE Portuguese Bioengineering Comittee, 22-23 February 2019, Lisbon, Portugal.
Avaliador

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2022/02/18 UMinho: Grupo 3B’s cria pela primeira vez fibras óticas vivas Mais Guimarães
2021/11/15 This Month in Pictures Advanced Science News
2021/10/11 Nanowerk Spotlight Nanowerk

Entrevista / Programa (rádio / tv)

Programa Tema
2022 - Atual Rádio Renascença Interview Investigadores criam fibras óticas vivas. Uma revolução no campo da bioengenharia
2022 - Atual UMinho I&D - Interview

Membro de associação

Nome da associação Tipo de participação
2017 - Atual PhDynamics Initiative Founder and Leader
2019/11 - 2020/03 University of Minho Doctoral College I3B's PhD Student Representative

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2021/09 - 2022/09 I3B's Council PhD Student Representative
Membro
 Biomaterials Biodegradables and Biomimetics, Portugal
Distinções

Prémio

2023 Julia Polak European Doctorate Award
European Society for Biomaterials , França
2022 The Best and Biggest of Technological Portugal - Innovation Awards, 1st Place
VISAO Press Group, Portugal
2021 Best Review Publication of 2020
Biomaterials Biodegradables and Biomimetics, Portugal
2021 Alfredo da Silva Scientific Investigation Award - Honorable Mention (top 2)
Fundação Amélia de Mello, Portugal

COTEC Portugal, Portugal
2019 DGES Merit Scholarship
Direção-Geral Do Ensino Superior, Portugal
2017 Best Tissue Engineering Idea
Universidade do Minho, Portugal

Outra distinção

2021 Stanford PHIND Individual Seed Grant
Stanford University Department of Radiology, Estados Unidos
2021 Exceptional COVID19 FCT PhD Scholarship
Fundação para a Ciência e a Tecnologia, Portugal
2020 R&D@PhD FLAD Scholarship
Fundação Luso-Americana, Portugal
2020 Stanford RISE COVID-19 Crisis Response Seed Grant Program
Stanford University Chemistry Engineering & Medicine for Human Health, Estados Unidos
2017 FCT PhD Scholarship
Fundação para a Ciência e a Tecnologia, Portugal