Matilde Sangreman Proença Maia Marques (A91D-4363-0132)

Curriculum Vitae

Matilde Sangreman Proença Maia Marques

Currently enrolled in the Ph.D program in Biotechnology and Biosciences from Instituto Superior Técnico (IST), Lisbon University (UL), my research focuses on increasing octocorals resilience towards climate change scenarios through microbiome manipulation, as well as exploring octocoral-associated viruses. In my PhD project, in collaboration with Lisbon Oceanarium, I am studying the octocoral microbiome of manmade marine ecosystems and their putative role in the preservation of microbial symbionts of octocorals. To implement microbiome therapy for octocorals, I am a visiting researcher at the Red Sea Research Centre (RSRC) at King Abdullah University for Science and Technology (KAUST), where I am currently running aquarium experiments to study the octocoral holobiont response to temperature and pathogen stress. I obtained my Master's degree in Biotechnology in December 2019 from IST-UL, and my Bachelor's degree in Biology, with specialization in Molecular Biology and Genetics, in July 2017 from Faculdade de Ciências (UL). My Master's studies received the Academic Merit Diploma in 2019 and the Academic Excellence Diploma in 2020. In my master thesis, I investigated the bioactivity of chemical extracts from marine bacterial symbionts of octocorals and marine sponges against human lung and breast cancer cells. I performed phenotypic and genotypic screenings of these bacterial isolates, and applied functional genomics and bioinformatics tools to assess their secondary metabolite coding potential. After my Master's studies, I deepened my scientific training in marine metagenomics, annotating metagenome-assembled genomes (MAGs) from uncultured Planktomarina sp. (Alphaproteobacteria) of the Atlantic Ocean. During my Bachelor, I have worked in the area of phytoremediation, assessing the impact of environmental stresses on the fatty acid profile and genetic expression of the brown mustard (Brassica juncea). Fascinated by the myriad facets of Biology, during my undergraduate studies, I also completed an internship in the Laboratory of Molecular Biology and HIV Epidemiology (Faculty of Pharmacy, UL) and attended workshops related with Forensic Entomology and Biological and Forensic Anthropology. So far, I have authored/co-authored four research articles in international, peer-reviewed journals and presented my work in over 15 oral and poster communications at multiple international and national scientific conferences, meetings and workshops. I am an organized person with a happy heart, who enjoys working in teams that offer a versatile and multidisciplinary environment. In my academic as well as personal life, I value balance, learning new things and sharing knowledge and experiences.

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Identificação

Identificação pessoal

Nome completo: Matilde Sangreman Proença Maia Marques

Nomes de citação

Marques, Matilde

Identificadores de autor

Ciência ID: A91D-4363-0132
ORCID iD: 0000-0001-9443-0893
Google Scholar ID: XHbvH2QAAAAJ

Endereços de correio eletrónico

matildesangremanmarques@tecnico.ulisboa.pt (Profissional)

Moradas

Av. Rovisco Pais 1, 1049-001, Lisbon, Lisbon, Portugal (Profissional)

Websites

https://www.linkedin.com/in/matildesangremanmarques/ (Profissional)
https://scholar.google.com/citations?hl=pt-PT&user=XHbvH2QAAAAJ (Profissional)
https://marinemicrobiomeslab.kaust.edu.sa/people/detail/matilde-marques (Profissional)
https://orcid.org/0000-0001-9443-0893 (Profissional)
https://www.facebook.com/MicroEcoEvo/ (Rede social)
https://www.instagram.com/microecoevo/ (Rede social)

Domínios de atuação

Ciências Naturais - Ciências Biológicas - Biologia Marinha
Ciências Naturais - Ciências Biológicas - Biologia
Ciências Médicas e da Saúde - Biotecnologia Médica - Biotecnologia Aplicada à Saúde

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão
Português (Idioma materno)
Inglês	Utilizador proficiente (C1)	Utilizador proficiente (C2)	Utilizador independente (B2)	Utilizador proficiente (C1)
Francês	Utilizador elementar (A1)	Utilizador independente (B1)	Utilizador elementar (A2)	Utilizador independente (B1)

Formação

	Grau	Classificação
2021/02/05 - 2025/02/05 Em curso	Biotecnologia e Biociências (Doutoramento) Universidade de Lisboa Instituto Superior Técnico, Portugal "Microbiome therapy for improved coral health and reef resilience" (TESE/DISSERTAÇÃO)
2017/09 - 2019/12 Concluído	Biotecnologia (Mestrado) Universidade de Lisboa Instituto Superior Técnico, Portugal "Assessment of anticancer activities in marine sponge- and coral-associated bacteria" (TESE/DISSERTAÇÃO)	17
2014/09 - 2017/07 Concluído	Biologia (Licenciatura) Especialização em Molecular e Genética Universidade de Lisboa Faculdade de Ciências, Portugal	14

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2023/08/06 - Atual	Investigador visitante (Investigação)	King Abdullah University of Science and Technology, Arábia Saudita

2022/09/24 - 2022/12/02	Investigador visitante (Investigação)	King Abdullah University of Science and Technology, Arábia Saudita

2020/05/01 - 2021/04/30	Assistente de Investigação (carreira) (Investigação)	Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
	Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2020/01/01 - 2020/04/30	Estagiário de Investigação (Investigação)	Universidade de Lisboa Instituto Superior Técnico, Portugal
	Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2016/10 - 2017/05	Volunteer Researcher	Universidade de Lisboa Faculdade de Farmácia, Portugal

Projetos

Bolsa

	Designação	Financiadores
2023/02/01 - Atual	Blue Bioeconomy Pact (PBA) - Recovery and Resilience Plan (PRR); Active on Work Package WP9 - Portuguese Blue Biobank C632741873-00467082 Bolseiro de Doutoramento Universidade de Lisboa Instituto Superior Técnico, Portugal	European Union (NextGenerationEU) Em curso
2020/05/01 - 2021/04/30	Symbioreactor - Sustainable production of bioactive metabolites from microbial symbionts of marine sponges and corals. FA05-2017-032 Bolseiro de Investigação Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal	Direção-Geral de Política do Mar Em curso

Produções

Publicações

Artigo em revista	Joana F. Couceiro; Matilde Marques; Sandra G. Silva; Tina Keller-Costa; Rodrigo Costa. "Aquimarina aquimarini sp. nov. and Aquimarina spinulae sp. nov., novel bacterial species with versatile natural product biosynthesis potential isolated from marine sponges". International Journal of Systematic and Evolutionary Microbiology (2024): https://doi.org/10.1099/ijsem.0.006228. 10.1099/ijsem.0.006228 João F. Almeida; Matilde Marques; Vanessa Oliveira; Conceição Egas; Dalila Mil-Homens; Romeu Viana; Daniel F. R. Cleary; et al. "Marine Sponge and Octocoral-Associated Bacteria Show Versatile Secondary Metabolite Biosynthesis Potential and Antimicrobial Activities against Human Pathogens". Marine Drugs (2022): https://doi.org/10.3390/md21010034. 10.3390/md21010034 Couceiro, Joana F.; Keller-Costa, Tina; Marques, Matilde; Kyrpides, Nikos C.; Woyke, Tanja; Whitman, William B.; Costa, Rodrigo. Autor correspondente: Costa, Rodrigo. "The Roseibium album (Labrenzia alba) Genome Possesses Multiple Symbiosis Factors Possibly Underpinning Host-Microbe Relationships in the Marine Benthos". Microbiology Resource Announcements 10 34 (2021): http://dx.doi.org/10.1128/mra.00320-21. Publicado • 10.1128/mra.00320-21 Marques, Matilde; Borges, Nuno; Silva, Sandra Godinho; da Rocha, Ulisses Nunes; Lago-Lestón, Asunción; Keller-Costa, Tina; Costa, Rodrigo. "Metagenome-Assembled Genome Sequences of Three Uncultured Planktomarina sp. Strains from the Northeast Atlantic Ocean". Microbiology Resource Announcements 9 12 (2020): http://dx.doi.org/10.1128/mra.00127-20. Publicado • 10.1128/mra.00127-20
Poster em conferência	Marques, Matilde; Santos, Elsa; Baylina, Núria; Raquel Peixoto; Keller-Costa, Tina; Costa, Rodrigo. "Insights into the culturable bacterial community of long-term aquarium tropical octocorals". Trabalho apresentado em Congress of Microbiology and Biotechnology, 2023. Marques, Matilde; Santos, Elsa; Baylina, Núria; Raquel Peixoto; Keller-Costa, Tina; Costa, Rodrigo. "Insights into the culturable bacterial community of long-term aquarium tropical octocorals". Trabalho apresentado em Encontro Ciência, 2023. Couceiro, Joana F.; Marques, Matilde; Silva, Sandra G.; Keller-Costa, Tina; Costa, Rodrigo. "Aquimarina aquimarinae sp. nov. and Aquimarina spinosulus sp. nov., new bacterial species with versatile natural product biosynthesis potential". Trabalho apresentado em Bacterial Genetics and Ecology, 2023. Marques, Matilde; Santos, Elsa; Baylina, Núria; Raquel Peixoto; Keller-Costa, Tina; Costa, Rodrigo. "Insights into the culturable bacterial community of long-term aquarium tropical octocorals". Trabalho apresentado em Bacterial Genetics and Ecology, 2023. João Fragoso Almeida; Marques, Matilde; Oliveira, Vanessa; Conceição Egas; Mil-Homens, Dalila; Viana, Romeu; Cleary, D.; et al. "Marine Sponge and Octocoral-Associated Bacteria Show Versatile Secondary Metabolite Biosynthesis Potential and Antimicrobial Activities against Human Pathogens". Trabalho apresentado em Bacterial Genetics and Ecology, 2023. João Fragoso Almeida; Marques, Matilde; Oliveira, Vanessa; Conceição Egas; Mil-Homens, Dalila; Viana, Romeu; Cleary, D.; et al. "Marine Sponge and Octocoral-Associated Bacteria Show Versatile Secondary Metabolite Biosynthesis Potential and Antimicrobial Activities against Human Pathogens". Trabalho apresentado em International Conference on Culture Collections, 2023. Marques, Matilde; Keller-Costa, Tina; Lago-Lestón, Asunción; Ulisses Nunes da Rocha; Kyrpides, Nikos C.; Páez-Espino, David; Costa, Rodrigo. "Functional and comparative metagenomics of viral communities in healthy and diseased octocoral tissue and seawater". Trabalho apresentado em International Coral Reef Symposium, 2022. Marques, Matilde; Almeida, João; Mil-Homens, Dalila; Fialho, Arsénio; Oliveira, Vanessa; Gomes, Newton; Costa, Rodrigo; Keller-Costa, Tina. "Bioprospecting bacterial symbionts of marine animals: sponge and coral-associated Gammaproteobacteria inhibit growth of notorious human and aquaculture pathogens". Trabalho apresentado em Microbiotec21, 2021. Marques, Matilde; Keller-Costa, Tina; Lago-Lestón, Asunción; Ulisses Nunes da Rocha; Kyrpides, Nikos C.; Páez-Espino, David; Costa, Rodrigo. "Functional and comparative metagenomics of viral communities in healthy and diseased octocoral tissue and seawater". Trabalho apresentado em Microbiotec21, 2021. Couceiro, Joana F.; Keller-Costa, Tina; Marques, Matilde; Kyrpides, Nikos C.; Woyke, Tanja; Whitman, William B.; Costa, Rodrigo. "The Roseibium album (Labrenzia alba) pangenome reveals multiple symbiosis factors likely underpinning host-microbe relationships in the marine benthos". Trabalho apresentado em Congress of Microbiology and Biotechnology, 2021. Marques, Matilde; Keller-Costa, Tina; Raquel Peixoto; Costa, Rodrigo. "Microbiome therapy for improved octocoral health and reef resilience". Trabalho apresentado em MIT Portugal Annual Conference, 2021. Marques, Matilde; Silva, Sandra G.; Bernardes, Nuno; Keller-Costa, Tina; Fialho, Arsénio; Costa, Rodrigo. "Extracellular metabolites from Aquimarina (Bacteroidetes) species possess promising anticancer activity". Trabalho apresentado em Congresso de Microbiologia e Biotecnologia, 2019.
Tese / Dissertação	Marques, Matilde. "Assessment of anticancer activities in marine sponge- and coral-associated bacteria". Mestrado, Universidade de Lisboa Instituto Superior Técnico, 2019.
Tradução	SECORE International, Inc.. Coral Heroes. 2023. Aceite para publicação

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2022/10/18	Aquimarina aquimarinae sp. nov. e Aquimarina spinosulus sp. nov., novas espécies bacterianas com potencial biossintético de produtos naturais	Microbiologia 2022
2022/09/20	Microbiome therapy for improved octocoral health and reef resilience	MIT Portugal Annual Conference (Portugal)
2021/09/23	Marine host-associated bacteria show versatile secondary metabolite biosynthesis capacities and antimicrobial activities	Congress of Microbiology and Biotechnology

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2018/03 - 2018/03	Collaborator in the IV Bioengineering Week. As a receptionist, I greeted speakers and attendees, signed them in and directed them to their destination. As a publicist, I advertised different activities occurring during the event to the target-audience. (2018/03) Conferência (Membro da Comissão Organizadora)	Universidade de Lisboa Instituto Superior Técnico, Portugal

Participação em evento

	Descrição da atividade Tipo de evento	Nome do evento Instituição / Organização
2023/07/04 - 2023/07/05	Metagenomic and bioinformatic insights into microbial communities. Oficina (workshop)	Meta_Microbial: Metagenomic and bioinformatic insights into microbial communities Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2023/05/20 - 2023/05/20	Engagement with the public, showcasing „The wonderful world of marine bacteria“ Exposição	Dia do Técnico Universidade de Lisboa Instituto Superior Técnico, Portugal
2023/04/05 - 2023/04/05	Exploring key oral communication skills, to ultimately contribute to better presentations of scientific work when addressing peers or lay people. Oficina (workshop)	Oral Communication Massachusetts Institute of Technology MIT Portugal Program, Portugal
2022/08/29 - 2022/09/02	Introduction to core computational skills, including task automation, version control, and modular programming. Oficina (workshop)	Software Carpentry Wellcome Sanger Institute, Reino Unido
2022/06/20 - 2022/07/01	Overview of Python language with an emphasis on biology related practical problem solving, using examples and exercises drawn from various aspects of bioinformatics work. Oficina (workshop)	Introduction to Python for Biologists Wellcome Sanger Institute, Reino Unido
2022/05/23 - 2022/05/23	Dia do Técnico 2022 exhibitor; engagement with the public, showcasing „The wonderful world of marine bacteria“ Exposição	Dia do Técnico Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/09/16 - 2021/09/21	Introduction on how to keep students engaged, key aspects of students-centered learning for effective learning and strategies to develop as a teacher. Oficina (workshop)	Teaching STEM Students - Transformation Guide for Teaching Assistants Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/12 - 2019/12	Initiation on Data Management focusing on its applicability and importance. The consequences of researchers using different platforms with different classification criteria were discussed. A Data Management Plan was then created and discussed. Oficina (workshop)	Ready for BioData Management? Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/09 - 2019/09	Participation on a dissemination stand about marine bacteria as a team member of the Research Group Microbial Ecology and Marine Metagenomics, from Instituto de Bioengenharia e Biociências (iBB), Instituto Superior Técnico. Conferência	Dia Internacional do Microrganismo Universidade de Lisboa Instituto Superior Técnico, Portugal
2018/03 - 2018/03	Presentation of the different areas of Anthropology, with examples of where and who can practice it. Hands-on exercise where age assessment and a sexual diagnosis where performed on human bones. Oficina (workshop)	Antropologia Biológica e Forense: O que dizem os nossos ossos sobre nós? Centro de Investigação Interdisciplinar Egas Moniz, Portugal
2018/03 - 2018/03	Introduction to the relevance of Networking based on true stories, either due to self-initiative or by chance. The importance of philanthropic networking was also discussed. Oficina (workshop)	Networking Skills: Tips and Tricks to Connect Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/02 - 2017/02	Introduction to Forensic Entomology and the stages of human decomposition and respective insect succession. Presentation of morphological characteristics of insects followed by sampling, identification and conservation of Diptera and Coleoptera of forensic interest. Oficina (workshop)	Entomologia Forense Universidade de Lisboa Faculdade de Ciências, Portugal
2013/09 - 2014/06	Designing and execution of projects based on ONU's Sustainable Development Goals to tackle community issues (such as poverty and elderly abandonment). Outro	VI Edição do Projeto “Make It Possible” AIESEC Portugal, Portugal

Membro de associação

	Nome da associação	Tipo de participação
2021 - Atual	Portuguese Society for Microbiology (SPM) https://spmicrobiologia.wordpress.com/	Active Member

Distinções

Prémio

2021	Best Poster Communication Award in Microbiotec21

Título

2023	Advanced Adventure Diver
2018	SDI Open Water Scuba Diver SDI/TDI, Portugal

Outra distinção

2020	Academic Excellence Diploma for my Masters in Biotechnology Universidade de Lisboa Instituto Superior Técnico, Portugal
2019	Academic Merit Diploma for my Masters Studies Universidade de Lisboa Instituto Superior Técnico, Portugal