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Sílvia Socorro is Full Professor of Biomedicine at the Faculty of Health Sciences of University of Beira Interior (UBI) and the Vice-Rector for Research, Innovation and Development. Silvia Socorro has a PhD in Biological Sciences (2001) and obtained the Habilitation degree in Biomedicine in 2013. She taught several curricular units of B.Sc., M.Sc. and Ph.D. programmes, namely the Ph.D. programme in Biomedicine, being responsible for the Scientific Writing modules. Research interests cover the action of sex steroid hormones, endocrine disruptors and other metabolic regulators in the control of cell survival, energy metabolism and calcium homeostasis in male reproduction and prostate cancer. Sílvia Socorro has supervised 3 post-doctoral projects and 7 PhD theses and co-authored more than 80 articles (Scopus h-index 28) in specialized journals in the fields of cell and molecular biology, reproduction and cancer. She is a member of the Editorial Board of international indexed journals and a member of national and international scientific organizations, namely, the ASPIC (Portuguese Association for Cancer Research) and the EACR (European Association for Cancer Research).
Identificação

Identificação pessoal

Nome completo
Sílvia Cristina da Cruz Marques Socorro

Nomes de citação

  • Socorro, Sílvia

Identificadores de autor

Ciência ID
AB17-5C25-1F2C
ORCID iD
0000-0001-8181-488X
Google Scholar ID
https://scholar.google.pt/citations?user=PA3L_h8AAAAJ&hl=pt-PT
Researcher Id
G-2285-2010
Scopus Author Id
23097994600

Endereços de correio eletrónico

  • ssocorro@fcsaude.ubi.pt (Profissional)

Telefones

Telefone
  • 275329053 (Profissional)

Moradas

  • Universidade da Beira Interior, Faculdade de Ciências da Saúde. Av. Infante D. Henrique , 6200-506, Covilhã, Covilhã, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Fisiologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador independente (B2) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador independente (B2)
Formação
Grau Classificação
2013
Concluído
Biomedicina (Título de Agregado)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2001
Concluído
Ciências Biológicas (Doutoramento)
Universidade do Algarve, Portugal
"Cloning and characterisation of seabream (Sparus aurata) estrogen receptors." (TESE/DISSERTAÇÃO)
1994
Concluído
Biologia Marinha (Licenciatura)
Universidade do Algarve, Portugal
"Estimulação por esteróides e gonadotrofina da maturação final in vitro de ovócitos em Halobatrachus didactylus. " (TESE/DISSERTAÇÃO)
17
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2002 - Atual Investigador (Investigação) Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2001 - 2002 Investigador Auxiliar Convidado (carreira) (Investigação) Universidade do Algarve, Portugal
Centro de Ciências do Mar, Portugal
2001 - 2001 Investigador Auxiliar Convidado (carreira) (Investigação) Ottawa Health Research Institute, Ottawa Hospita, Canadá
1994 - 2000 Investigador (Investigação) Universidade do Algarve, Portugal
Centro de Ciências do Mar, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2019 - Atual Professor Catedrático (Docente Universitário) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2016/10/01 - 2019 Professor Associado (Docente Universitário) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2004 - 2016 Professor Auxiliar (Docente Universitário) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2002 - 2004 Professor Auxiliar Convidado (Docente Universitário) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2023 - Atual Director Non-Degree Course Project Management for Researchers Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2023 - Atual Director Non-Degree Course Applying for Funding Tools for Researchers Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2021/06/08 - Atual Vice-Reitor Universidade da Beira Interior, Portugal
2019/10/01 - 2021/06/01 Director de Unidade Orgânica Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2017 - 2021 Director PhD Programme Biomedicine Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2009 - 2021 Member of the Scientific Council Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2015/11/01 - 2019/09/30 Subdirector de Unidade Orgânica Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2017 - 2019 Secretary of the Scientific Council Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2017 - 2019 Member of the Pedagogical Council Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2009 - 2013 Member of the Faculty Council Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2006 - 2011 Director of the 1st cycle of studies in Biomedical Sciences Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
Projetos

Bolsa

Designação Financiadores
2022 - 2023 MICROBIO-PCa - Estudo das alterações metabólicas do cancro da próstata desencadeadas pelo bacterioma: implicações na progressão da doença e na clínica
MICROBIO-PCa
Co-Investigador Responsável (Co-IR)
Liga Portuguesa Contra o Cancro
Em curso
2022 - 2023 ARGOS - Desregulação do tecido Adiposo peRiprostático induzida por químicos ambientais e aGressividade do cancrO da próstata
ARGOS
Co-Investigador Responsável (Co-IR)
Associação Portuguesa de Urologia
Em curso
2022 - 2023 MICROBIO-PCa - Estudo das alterações metabólicas do cancro da próstata desencadeadas pelo bacterioma: implicações na progressão da doença e na clínica
MICROBIO-PCa
Liga Portuguesa Contra o Cancro
2001 - 2002 Genes and sex change: steroid receptors and novel genes in seabream (Sparus aurata)
BPD/7129/2001
Bolseiro de Pós-Doutoramento
Ministério da Ciência Tecnologia e Ensino Superior
1996 - 2000 Cloning and characterisation of seabream (Sparus aurata) estrogen receptors.
BD/9214/96
Bolseiro de Doutoramento
Ministério da Ciência Tecnologia e Ensino Superior

Projeto

Designação Financiadores
2022 - 2024 U*Night - The UNITA Researchers' Night
HORIZON-MSCA-2022-CITIZENS-01-01, HORIZON-CSA, Project number: 101061610
Co-Investigador Responsável (Co-IR)
Horizon Europe
Em curso
2021 - 2023 CICS4COVID - Testar, Rastrear, e Inovar no Diagnóstico da COVID-19
CENTRO-01-0145-FEDER-072541
Investigador responsável
Comissão de Coordenação e Desenvolvimento Regional do Centro
Concluído
2019 - 2023 COST Action CA18124 "European Sexual Medicine Network”.
Co-Investigador Responsável (Co-IR)
Em curso
2018/07 - 2022 Shaping prostate cell metabolism by extrinsic factors: insights into cancer prevention, diagnosis and treatment
POCI-01-0145-FEDER-029114
Investigador responsável
Fundação para a Ciência e a Tecnologia
2018 - 2022 C4 – Cloud Computing Competences Centre
Investigador
Comissão de Coordenação e Desenvolvimento Regional do Centro
Concluído
2020 - 2021 Track and Trace COVID-19
Projeto nº 149
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2016/09 - 2020 "Tribbles Research and Innovation Network (TRAIN)"
EU project 721532
Investigador responsável
European Commission
2013 - 2015 Hormonal and Inflammatory basis of age-related diseases
CENTRO-07-ST24-FEDER-002015
Investigador
Comissão de Coordenação e Desenvolvimento Regional do Centro, Programa Operacional Regional do Centro 2007-2013 QREN
2012 - 2015 Can Hormonal (De)regulation of Ion Transporters in Human Sertoli Cells be Responsible for Infertility?
Investigador
Fundação para a Ciência e a Tecnologia, I.P.
2005/09 - 2008/08 Regulation of human and mouse transthyretin levels in liver and choroid plexus by steroid hormones.
Investigador
Fundação para a Ciência e a Tecnologia, I.P.
Produções

Publicações

Artigo em conferência
  1. Correia, Sara; Alves, Mário R; Martins, Ana D; Cavaco, José E; Oliveira, Pedro F; Socorro, Sílvia. "Effect of 17[beta]-estradiol on germ cell apoptosis by modulating the expression of SCF/c-kit, FasL/FasR and regucalcin". Trabalho apresentado em 16th European Congress of Endocrinology, 2014.
    Publicado • 10.1530/endoabs.35.P702
  2. Ricardo J Marques; Vaz, CV; Peres, Carina; Gomes, I.; SANTOS, Cecilia R A; Maia, Cláudio J. B.; Socorro, Sílvia. "177 Effect of Androgens on the Expression of Ca2+-binding Protein, Regucalcin, and Ca2+-channels in MCF-7 Cells". 2012.
    10.1016/s0959-8049(12)70876-6
Artigo em revista
  1. Filipa Duarte; Mariana Feijó; Ângelo Luís; Sílvia Socorro; Cláudio J. Maia; Sara Correia. "Propolis Protects GC-1spg Spermatogonial Cells against Tert-Butyl Hydroperoxide-Induced Oxidative Damage". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms25010614.
    10.3390/ijms25010614
  2. Rocha, Sandra M.; Santos, Fátima M.; Socorro, Sílvia; Passarinha, Luís A.; Maia, Cláudio J.. "Proteomic analysis of STEAP1 knockdown in human LNCaP prostate cancer cells". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1870 7 (2023): 119522. http://dx.doi.org/10.1016/j.bbamcr.2023.119522.
    10.1016/j.bbamcr.2023.119522
  3. Sandra M. Rocha; Daniel Nascimento; Rafaella S. Coelho; Ana Margarida Cardoso; Luís A. Passarinha; Sílvia Socorro; Cláudio J. Maia. "STEAP1 Knockdown Decreases the Sensitivity of Prostate Cancer Cells to Paclitaxel, Docetaxel and Cabazitaxel". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24076643.
    10.3390/ijms24076643
  4. Rocha, Sandra; Nascimento, Daniel; Cardoso, Ana; Passarinha, Luís; Socorro, Sílvia; Maia, Cláudio. "STEAP1 regulation and its influence modulating the response of LNCaP prostate cancer cells to bicalutamide, enzalutamide and apalutamide". Molecular Medicine Reports 27 2 (2023): http://dx.doi.org/10.3892/mmr.2023.12939.
    Publicado • 10.3892/mmr.2023.12939
  5. Henrique J. Cardoso; Marília I. Figueira; Tiago M.A. Carvalho; Catarina D.M. Serra; Cátia V. Vaz; Patrícia A. Madureira; Sílvia Socorro. "Androgens and low density lipoprotein-cholesterol interplay in modulating prostate cancer cell fate and metabolism". Pathology - Research and Practice (2022): https://doi.org/10.1016/j.prp.2022.154181.
    10.1016/j.prp.2022.154181
  6. Sandra M. Rocha; Sílvia Socorro; Luís A. Passarinha; Cláudio J. Maia. "Comprehensive Landscape of STEAP Family Members Expression in Human Cancers: Unraveling the Potential Usefulness in Clinical Practice Using Integrated Bioinformatics Analysis". Data 7 5 (2022): 64-64. https://doi.org/10.3390/data7050064.
    10.3390/data7050064
  7. Sandra Rocha; Inês Sousa; Inês M. Gomes; Patrícia Arinto; Pedro Costa-Pinheiro; Eduarda Coutinho; Cecília R A Santos; et al. "Promoter Demethylation Upregulates STEAP1 Gene Expression in Human Prostate Cancer: In Vitro and In Silico Analysis". Life (2021): https://www.mdpi.com/2075-1729/11/11/1251.
    10.3390/life11111251
  8. Josué Carvalho; Jéssica Lopes-Nunes; Joana Figueiredo; Tiago Santos; André Miranda; Micaela Riscado; Fani Sousa; et al. "Molecular Beacon Assay Development for Severe Acute Respiratory Syndrome Coronavirus 2 Detection". Sensors 21 21 (2021): 7015-7015. https://doi.org/10.3390/s21217015.
    10.3390/s21217015
  9. Roberta V. L. Martins; Ana M. S. Silva; Ana Paula Duarte; Sílvia Socorro; Sara Correia; Cláudio J. Maia. "Natural Products as Protective Agents for Male Fertility". BioChem 1 3 (2021): 122-147. https://doi.org/10.3390/biochem1030011.
    10.3390/biochem1030011
  10. Lara R. S. Fonseca; Gonçalo R. Silva; Ângelo Luís; Henrique J. Cardoso; Sara Correia; Cátia V. Vaz; Ana P. Duarte; Sílvia Socorro. "Sweet Cherries as Anti-Cancer Agents: From Bioactive Compounds to Function". Molecules 26 10 (2021): 2941-2941. https://doi.org/10.3390/molecules26102941.
    10.3390/molecules26102941
  11. Feijó, Mariana; Martins, Roberta V L; Socorro, Sílvia; Pereira, Luísa; Correia, Sara. "Effects of the endocrine disruptor vinclozolin in male reproduction: a systematic review and meta-analysis". Biology of Reproduction (2021): http://dx.doi.org/10.1093/biolre/ioab018.
    Publicado • 10.1093/biolre/ioab018
  12. Henrique J. Cardoso; Marília I. Figueira; Cátia V. Vaz; Tiago M. A. Carvalho; Luís A. Brás; Patrícia A. Madureira; Paulo J. Oliveira; Vilma A. Sardão; Sílvia Socorro. "Glutaminolysis is a metabolic route essential for survival and growth of prostate cancer cells and a target of 5a-dihydrotestosterone regulation". Cellular Oncology (2021): https://doi.org/10.1007/s13402-020-00575-9.
    10.1007/s13402-020-00575-9
  13. Henrique J. Cardoso; Tiago M. A. Carvalho; Lara R. S. Fonseca; Marília I. Figueira; Cátia V. Vaz; Sílvia Socorro. "Revisiting prostate cancer metabolism: From metabolites to disease and therapy". Medicinal Research Reviews (2020): https://doi.org/10.1002/med.21766.
    10.1002/med.21766
  14. Silva, Ana M.S.; Socorro, Sílvia; Hurtado de Llera, Ana; Vaz, Cátia V.; Correia, Sara; Maia, Cláudio J.. "Overexpression of regucalcin mitigates the ageing-related changes in oxidative stress and sperm quality". Theriogenology 157 (2020): 472-482. http://dx.doi.org/10.1016/j.theriogenology.2020.08.028.
    10.1016/j.theriogenology.2020.08.028
  15. Silva, Gonçalo R.; Vaz, Cátia V.; Catalão, Beatriz; Ferreira, Susana; Cardoso, Henrique J.; Duarte, Ana Paula; Socorro, Sílvia. "Sweet Cherry Extract Targets the Hallmarks of Cancer in Prostate Cells: Diminished Viability, Increased Apoptosis and Suppressed Glycolytic Metabolism". Nutrition and Cancer 11 (2019): 1-15. http://dx.doi.org/10.1080/01635581.2019.1661502.
    Publicado • 10.1080/01635581.2019.1661502
  16. Tiago MA. Carvalho; Henrique J. Cardoso; Marília I. Figueira; Cátia V. Vaz; Sílvia Socorro. "The peculiarities of cancer cell metabolism: A route to metastasization and a target for therapy". European Journal of Medicinal Chemistry 171 (2019): 343-363. https://doi.org/10.1016/j.ejmech.2019.03.053.
    10.1016/j.ejmech.2019.03.053
  17. Henrique J. Cardoso; Cátia V. Vaz; Tiago M.A. Carvalho; Marília I. Figueira; Sílvia Socorro. "Tyrosine kinase inhibitor imatinib modulates the viability and apoptosis of castrate-resistant prostate cancer cells dependently on the glycolytic environment". Life Sciences 218 (2019): 274-283. https://doi.org/10.1016/j.lfs.2018.12.055.
    10.1016/j.lfs.2018.12.055
  18. Inês Mateus; Mariana Feijó; Luís M. Espínola; Cátia V. Vaz; Sara Correia; Sílvia Socorro. "Glucose and glutamine handling in the Sertoli cells of transgenic rats overexpressing regucalcin: plasticity towards lactate production". Scientific Reports (2018): https://doi.org/10.1038/s41598-018-28668-4.
    10.1038/s41598-018-28668-4
  19. Henrique J. Cardoso; Marília I. Figueira; Sílvia Socorro. "The stem cell factor (SCF)/c-KIT signalling in testis and prostate cancer". Journal of Cell Communication and Signaling (2017): https://doi.org/10.1007/s12079-017-0399-1.
    10.1007/s12079-017-0399-1
  20. Marília I. Figueira; Henrique J. Cardoso; Sara Correia; Cláudio J. Maia; Sílvia Socorro. "The stem cell factor (SCF)/c-KIT system in carcinogenesis of reproductive tissues: What does the hormonal regulation tell us?". Cancer Letters 405 (2017): 10-21. https://doi.org/10.1016%2Fj.canlet.2017.07.017.
    10.1016/j.canlet.2017.07.017
  21. Correia, S.; Vaz, C.V.; Silva, A.M.S.; Cavaco, J.E.; Socorro, S.. "Regucalcin counteracts tert-butyl hydroperoxide and cadmium-induced oxidative stress in rat testis". Journal of Applied Toxicology 37 2 (2017): 159-166. http://www.scopus.com/inward/record.url?eid=2-s2.0-85002396873&partnerID=MN8TOARS.
    10.1002/jat.3333
  22. Maia, Cláudio Jorge; Rocha, Sandra Moreira; Socorro, Sílvia; Schmitt, Fernando; Santos, Cecília Reis. "Oligoadenylate synthetase 1 (OAS1) expression in human breast and prostate cancer cases, and its regulation by sex steroid hormones". Advances in Modern Oncology Research 2 2 (2016): 97. http://dx.doi.org/10.18282/amor.v2.i1.70.
    10.18282/amor.v2.i1.70
  23. Figueira, M.I.; Correia, S.; Vaz, C.V.; Cardoso, H.J.; Gomes, I.M.; Marques, R.; Maia, C.J.; Socorro, S.. "Estrogens down-regulate the stem cell factor (SCF)/c-KIT system in prostate cells: Evidence of antiproliferative and proapoptotic effects". Biochemical Pharmacology 99 (2016): 73-87. http://www.scopus.com/inward/record.url?eid=2-s2.0-84952638603&partnerID=MN8TOARS.
    10.1016/j.bcp.2015.11.016
  24. Vaz, C.V.; Marques, R.; Cardoso, H.J.; Maia, C.J.; Socorro, S.. "Suppressed glycolytic metabolism in the prostate of transgenic rats overexpressing calcium-binding protein regucalcin underpins reduced cell proliferation". Transgenic Research 25 2 (2016): 139-148. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946811164&partnerID=MN8TOARS.
    10.1007/s11248-015-9918-0
  25. Silva, A.M.S.; Correia, S.; Socorro, S.; Maia, C.J.. "Endogenous factors in the recovery of reproductive function after testicular injury and cancer". Current Molecular Medicine 16 7 (2016): 631-649. http://www.scopus.com/inward/record.url?eid=2-s2.0-84989247286&partnerID=MN8TOARS.
    10.2174/1566524016666160802150400
  26. Silva, A.M.S.; Correia, S.; Casalta-Lopes, J.E.; Mamede, A.C.; Cavaco, J.E.B.; Botelho, M.F.; Socorro, S.; Maia, C.J.. "The protective effect of regucalcin against radiation-induced damage in testicular cells". Life Sciences 164 (2016): 31-41. http://www.scopus.com/inward/record.url?eid=2-s2.0-84987923505&partnerID=MN8TOARS.
    10.1016/j.lfs.2016.09.003
  27. Vaz, C.V.; Correia, S.; Cardoso, H.J.; Figueira, M.I.; Marques, R.; Maia, C.J.; Socorro, S.. "The emerging role of regucalcin as a tumor suppressor: Facts and views". Current Molecular Medicine 16 7 (2016): 607-619. http://www.scopus.com/inward/record.url?eid=2-s2.0-84989246357&partnerID=MN8TOARS.
    10.2174/1566524016666160714124550
  28. Cátia V. Vaz; Ricardo Marques; Cláudio J. Maia; Sílvia Socorro. "Aging-associated changes in oxidative stress, cell proliferation, and apoptosis are prevented in the prostate of transgenic rats overexpressing regucalcin". Translational Research 166 6 (2015): 693-705. https://doi.org/10.1016/j.trsl.2015.08.009.
    10.1016/j.trsl.2015.08.009
  29. Marques, R.; Vaz, C.V.; Maia, C.J.; Gomes, M.; Gama, A.; Alves, G.; Santos, C.R.; Schmitt, F.; Socorro, S.. "Histopathological and in vivo evidence of regucalcin as a protective molecule in mammary gland carcinogenesis". Experimental Cell Research 330 2 (2015): 325-335. http://www.scopus.com/inward/record.url?eid=2-s2.0-84919789386&partnerID=MN8TOARS.
    10.1016/j.yexcr.2014.08.007
  30. Correia, S.; Cardoso, H.J.; Cavaco, J.E.; Socorro, S.. "Oestrogens as apoptosis regulators in mammalian testis: Angels or devils?". Expert Reviews in Molecular Medicine 17 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84927716482&partnerID=MN8TOARS.
    10.1017/erm.2014.25
  31. Gonçalves, C.; Bastos, M.; Pignatelli, D.; Borges, T.; Aragüés, J.M.; Fonseca, F.; Pereira, B.D.; Socorro, S.; Lemos, M.C.. "Novel FGFR1 mutations in Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism: Evidence for the involvement of an alternatively spliced isoform". Fertility and Sterility (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84940748757&partnerID=MN8TOARS.
    10.1016/j.fertnstert.2015.07.1142
  32. Vaz, C.V.; Marques, R.; Alves, M.G.; Oliveira, P.F.; Cavaco, J.E.; Maia, C.J.; Socorro, S.. "Androgens enhance the glycolytic metabolism and lactate export in prostate cancer cells by modulating the expression of GLUT1, GLUT3, PFK, LDH and MCT4 genes". Journal of Cancer Research and Clinical Oncology (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84930532325&partnerID=MN8TOARS.
    10.1007/s00432-015-1992-4
  33. Cardoso, H.J.; Vaz, C.V.; Correia, S.; Figueira, M.I.; Marques, R.; Maia, C.J.; Socorro, S.. "Paradoxical and contradictory effects of imatinib in two cell line models of hormone-refractory prostate cancer". Prostate 75 9 (2015): 923-935. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929996402&partnerID=MN8TOARS.
    10.1002/pros.22976
  34. Marques, R.; Peres, C.G.; Vaz, C.V.; Gomes, I.M.; Figueira, M.I.; Cairrão, E.; Verde, I.; Maia, C.J.; Socorro, S.. "5a-Dihydrotestosterone regulates the expression of L-type calcium channels and calcium-binding protein regucalcin in human breast cancer cells with suppression of cell growth". Medical Oncology 32 9 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84938787084&partnerID=MN8TOARS.
    10.1007/s12032-015-0676-x
  35. Vaz, C.V.; Rodrigues, D.B.; Socorro, S.; Maia, C.J.. "Effect of extracellular calcium on regucalcin expression and cell viability in neoplastic and non-neoplastic human prostate cells". Biochimica et Biophysica Acta - Molecular Cell Research 1853 10 (2015): 2621-2628. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939454739&partnerID=MN8TOARS.
    10.1016/j.bbamcr.2015.07.006
  36. Dias, T.R.; Alves, M.G.; Tomás, G.D.; Socorro, S.; Silva, B.M.; Oliveira, P.F.. "White tea as a promising antioxidant medium additive for sperm storage at room temperature: A comparative study with green tea". Journal of Agricultural and Food Chemistry 62 3 (2014): 608-617. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892999479&partnerID=MN8TOARS.
    10.1021/jf4049462
  37. Cardoso, H.J.; Figueira, M.I.; Correia, S.; Vaz, C.V.; Socorro, S.. "The SCF/c-KIT system in the male: Survival strategies in fertility and cancer". Molecular Reproduction and Development 81 12 (2014): 1064-1079. http://www.scopus.com/inward/record.url?eid=2-s2.0-84920051800&partnerID=MN8TOARS.
    10.1002/mrd.22430
  38. Correia, S.; Alves, M.G.; Oliveira, P.F.; Alves, M.R.; van Pelt, A.M.M.; Cavaco, J.E.; Socorro, S.. "Transgenic overexpression of regucalcin leads to suppression of thapsigargin- and actinomycin D-induced apoptosis in the testis by modulation of apoptotic pathways". Andrology 2 2 (2014): 290-298. http://www.scopus.com/inward/record.url?eid=2-s2.0-84894308909&partnerID=MN8TOARS.
    10.1111/j.2047-2927.2014.00186.x
  39. Oliveira, P.F.; Alves, M.G.; Martins, A.D.; Correia, S.; Bernardino, R.L.; Silva, J.; Barros, A.; et al. "Expression pattern of G protein-coupled receptor 30 in human seminiferous tubular cells". General and Comparative Endocrinology 201 (2014): 16-20. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897952706&partnerID=MN8TOARS.
    10.1016/j.ygcen.2014.02.022
  40. Figueira, M.I.; Cardoso, H.J.; Correia, S.; Maia, C.J.; Socorro, S.. "Hormonal regulation of c-KIT receptor and its ligand: implications for human infertility?". Progress in histochemistry and cytochemistry 49 1-3 (2014): 1-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-84919473944&partnerID=MN8TOARS.
    10.1016/j.proghi.2014.09.001
  41. Correia, S.; Alves, M.R.; Cavaco, J.E.; Oliveira, P.F.; Socorro, S.. "Estrogenic regulation of testicular expression of stem cell factor and c-kit: Implications in germ cell survival and male fertility". Fertility and Sterility 102 1 (2014): 299-306. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903381688&partnerID=MN8TOARS.
    10.1016/j.fertnstert.2014.04.009
  42. Vaz, C.V.; Maia, C.J.; Marques, R.; Gomes, I.M.; Correia, S.; Alves, M.G.; Cavaco, J.E.; Oliveira, P.F.; Socorro, S.. "Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways". Prostate 74 12 (2014): 1189-1198. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904658283&partnerID=MN8TOARS.
    10.1002/pros.22835
  43. Marques, R.; Maia, C.J.; Vaz, C.; Correia, S.; Socorro, S.. "The diverse roles of calcium-binding protein regucalcin in cell biology: From tissue expression and signalling to disease". Cellular and Molecular Life Sciences 71 1 (2014): 93-111. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891882606&partnerID=MN8TOARS.
    10.1007/s00018-013-1323-3
  44. Alves, M.G.; Martins, A.D.; Vaz, C.V.; Correia, S.; Moreira, P.I.; Oliveira, P.F.; Socorro, S.. "Metformin and male reproduction: Effects on Sertoli cell metabolism". British Journal of Pharmacology 171 4 (2014): 1033-1042. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893042451&partnerID=MN8TOARS.
    10.1111/bph.12522
  45. Rato, L.; Duarte, A.I.; Tomás, G.D.; Santos, M.S.; Moreira, P.I.; Socorro, S.; Cavaco, J.E.; Alves, M.G.; Oliveira, P.F.. "Pre-diabetes alters testicular PGC1-a/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress". Biochimica et Biophysica Acta - Bioenergetics 1837 3 (2014): 335-344. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892411578&partnerID=MN8TOARS.
    10.1016/j.bbabio.2013.12.008
  46. Martins, A.D.; Alves, M.G.; Simões, V.L.; Dias, T.R.; Rato, L.; Moreira, P.I.; Socorro, S.; Cavaco, J.E.; Oliveira, P.F.. "Control of Sertoli cell metabolism by sex steroid hormones is mediated through modulation in glycolysis-related transporters and enzymes". Cell and Tissue Research 354 3 (2013): 861-868. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890482473&partnerID=MN8TOARS.
    10.1007/s00441-013-1722-7
  47. Gärtner, A.; Pereira, T.; Alves, M.G.; Armada-da-Silva, P.A.S.; Amorim, I.; Gomes, R.; Ribeiro, J.; et al. "Corrigendum to Use of poly(DL-lactide-e-caprolactone) membranes and mesenchymal stem cells from the Wharton's jelly of the umbilical cord for promoting nerve regeneration in axonotmesis: In vitro and in vivo analysis [Differentiation 84 (2012) 355-365]". Differentiation 85 3 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84878909587&partnerID=MN8TOARS.
    10.1016/j.diff.2013.03.001
  48. Dias, T.R.; Martins, A.D.; Reis, V.P.; Socorro, S.; Silva, B.M.; Alves, M.G.; Oliveira, P.F.. "Glucose transport and metabolism in sertoli cell: Relevance for male fertility". Current Chemical Biology 7 3 (2013): 282-293. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901288156&partnerID=MN8TOARS.
  49. Bernardino, R.L.; Martins, A.D.; Socorro, S.; Alves, M.G.; Oliveira, P.F.. "Effect of prediabetes on membrane bicarbonate transporters in testis and epididymis". Journal of Membrane Biology 246 12 (2013): 877-883. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888216253&partnerID=MN8TOARS.
    10.1007/s00232-013-9601-4
  50. Alves, M.G.; Neuhaus-Oliveira, A.; Moreira, P.I.; Socorro, S.; Oliveira, P.F.. "Exposure to 2,4-dichlorophenoxyacetic acid alters glucose metabolism in immature rat Sertoli cells". Reproductive Toxicology 38 (2013): 81-88. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876339594&partnerID=MN8TOARS.
    10.1016/j.reprotox.2013.03.005
  51. Laurentino, S.S.; Pinto, P.I.S.; Tomás, J.; Cavaco, J.E.; Sousa, M.; Barros, A.; Power, D.M.; Canário, A.V.M.; Socorro, S.. "Identification of androgen receptor variants in testis from humans and other vertebrates". Andrologia 45 3 (2013): 187-194. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876814362&partnerID=MN8TOARS.
    10.1111/j.1439-0272.2012.01333.x
  52. Rato, L.; Alves, M.G.; Dias, T.R.; Lopes, G.; Cavaco, J.E.; Socorro, S.; Oliveira, P.F.. "High-energy diets may induce a pre-diabetic state altering testicular glycolytic metabolic profile and male reproductive parameters.". Andrology 1 3 (2013): 495-504. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885600016&partnerID=MN8TOARS.
  53. Alves, M.G.; Rato, L.; Carvalho, R.A.; Moreira, P.I.; Socorro, S.; Oliveira, P.F.. "Hormonal control of Sertoli cell metabolism regulates spermatogenesis". Cellular and Molecular Life Sciences 70 5 (2013): 777-793. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873719667&partnerID=MN8TOARS.
    10.1007/s00018-012-1079-1
  54. Simões, V.L.; Alves, M.G.; Martins, A.D.; Dias, T.R.; Rato, L.; Socorro, S.; Oliveira, P.F.. "Regulation of apoptotic signaling pathways by 5a-dihydrotestosterone and 17ß-estradiol in immature rat Sertoli cells". Journal of Steroid Biochemistry and Molecular Biology 135 1 (2013): 15-23. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874408605&partnerID=MN8TOARS.
    10.1016/j.jsbmb.2012.11.019
  55. Gomes, I.M.; Santos, C.R.; Socorro, S.; Maia, C.J.. "Six transmembrane epithelial antigen of the prostate 1 is down-regulated by sex hormones in prostate cells". Prostate 73 6 (2013): 605-613. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875803548&partnerID=MN8TOARS.
    10.1002/pros.22601
  56. Bernardino, R.L.; Jesus, T.T.; Martins, A.D.; Sousa, M.; Barros, A.; Cavaco, J.E.; Socorro, S.; Alves, M.G.; Oliveira, P.F.. "Molecular basis of bicarbonate membrane transport in the male reproductive tract". Current Medicinal Chemistry 20 32 (2013): 4037-4049. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887961875&partnerID=MN8TOARS.
    10.2174/15672050113109990200
  57. Alves, M.G.; Martins, A.D.; Rato, L.; Moreira, P.I.; Socorro, S.; Oliveira, P.F.. "Molecular mechanisms beyond glucose transport in diabetes-related male infertility". Biochimica et Biophysica Acta - Molecular Basis of Disease 1832 5 (2013): 626-635. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874414576&partnerID=MN8TOARS.
    10.1016/j.bbadis.2013.01.011
  58. Correia, S.; Oliveira, P.F.; Guerreiro, P.M.; Lopes, G.; Alves, M.G.; Canário, A.V.M.; Cavaco, J.E.; Socorro, S.. "Sperm parameters and epididymis function in transgenic rats overexpressing the Ca2+-binding protein regucalcin: A hidden role for Ca2+ in sperm maturation?". Molecular Human Reproduction 19 9 (2013): 581-589. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883162067&partnerID=MN8TOARS.
    10.1093/molehr/gat030
  59. Gärtner A; Pereira T; Alves MG; Armada-da-Silva PA; Amorim I; Gomes R; Ribeiro J; et al. "Use of poly(DL-lactide-e-caprolactone) membranes and mesenchymal stem cells from the Wharton's jelly of the umbilical cord for promoting nerve regeneration in axonotmesis: in vitro and in vivo analysis.". (2012): http://europepmc.org/abstract/med/23142731.
    10.1016/j.diff.2012.10.001
  60. Oliveira, P.F.; Alves, M.G.; Rato, L.; Laurentino, S.; Silva, J.; Sá, R.; Barros, A.; et al. "Effect of insulin deprivation on metabolism and metabolism-associated gene transcript levels of in vitro cultured human Sertoli cells". Biochimica et Biophysica Acta - General Subjects 1820 2 (2012): 84-89. http://www.scopus.com/inward/record.url?eid=2-s2.0-83455235851&partnerID=MN8TOARS.
    10.1016/j.bbagen.2011.11.006
  61. Vaz, C.V.; Alves, M.G.; Marques, R.; Moreira, P.I.; Oliveira, P.F.; Maia, C.J.; Socorro, S.. "Androgen-responsive and nonresponsive prostate cancer cells present a distinct glycolytic metabolism profile". International Journal of Biochemistry and Cell Biology 44 11 (2012): 2077-2084. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865554409&partnerID=MN8TOARS.
    10.1016/j.biocel.2012.08.013
  62. Rato, L.; Alves, M.G.; Socorro, S.; Carvalho, R.A.; Cavaco, J.E.; Oliveira, P.F.. "Metabolic modulation induced by oestradiol and DHT in immature rat Sertoli cells cultured in vitro". Bioscience Reports 32 1 (2012): 61-69. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855896846&partnerID=MN8TOARS.
    10.1042/BSR20110030
  63. Rato, L.; Alves, M.G.; Socorro, S.; Duarte, A.I.; Cavaco, J.E.; Oliveira, P.F.. "Metabolic regulation is important for spermatogenesis". Nature Reviews Urology 9 6 (2012): 330-338. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862208844&partnerID=MN8TOARS.
    10.1038/nrurol.2012.77
  64. Alves, M.G.; Oliveira, P.F.; Socorro, S.; Moreira, P.I.. "Impact of diabetes in blood-testis and blood-brain barriers: Resemblances and differences". Current Diabetes Reviews 8 6 (2012): 401-412. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870183874&partnerID=MN8TOARS.
    10.2174/157339912803529896
  65. Alves, M.G.; Socorro, S.; Silva, J.; Barros, A.; Sousa, M.; Cavaco, J.E.; Oliveira, P.F.. "In vitro cultured human Sertoli cells secrete high amounts of acetate that is stimulated by 17ß-estradiol and suppressed by insulin deprivation". Biochimica et Biophysica Acta - Molecular Cell Research 1823 8 (2012): 1389-1394. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862625700&partnerID=MN8TOARS.
    10.1016/j.bbamcr.2012.06.002
  66. Laurentino, S.S.; Correia, S.; Cavaco, J.E.; Oliveira, P.F.; de Sousa, M.D.; Barros, A.; Socorro, S.. "Regucalcin, a calcium-binding protein with a role in male reproduction?". Molecular Human Reproduction 18 4 (2012): 161-170. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858685367&partnerID=MN8TOARS.
    10.1093/molehr/gar075
  67. Pinto, P.I.S.; Teodósio, R.; Socorro, S.; Power, D.M.; Canário, A.V.M.. "Structure, tissue distribution and estrogen regulation of splice variants of the sea bream estrogen receptor a gene". Gene 503 1 (2012): 18-24. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861783170&partnerID=MN8TOARS.
    10.1016/j.gene.2012.04.081
  68. Laurentino, S.S.; Correia, S.; Cavaco, J.E.; Oliveira, P.F.; Rato, L.; Sousa, M.; Barros, A.; Socorro, S.. "Regucalcin is broadly expressed in male reproductive tissues and is a new androgen-target gene in mammalian testis". Reproduction 142 3 (2011): 447-456. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051992405&partnerID=MN8TOARS.
    10.1530/REP-11-0085
  69. Laurentino, S.; Gonalves, J.; Cavaco, J.E.; Oliveira, P.F.; Alves, M.G.; De Sousa, M.; Barros, A.; Socorro, S.. "Apoptosis-inhibitor Aven is downregulated in defective spermatogenesis and a novel estrogen target gene in mammalian testis". Fertility and Sterility 96 3 (2011): 745-750. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052262541&partnerID=MN8TOARS.
    10.1016/j.fertnstert.2011.06.009
  70. Oliveira, P.F.; Alves, M.G.; Rato, L.; Silva, J.; Sá, R.; Barros, A.; Sousa, M.; et al. "Influence of 5a-dihydrotestosterone and 17ß-estradiol on human Sertoli cells metabolism". International Journal of Andrology 34 6 PART 2 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-81455158931&partnerID=MN8TOARS.
    10.1111/j.1365-2605.2011.01205.x
  71. Gomes I; Santos CR; Socorro S; Lopes C; Maia CJ. "STEAP1 expression in prostate cancer and its regulation by androgens.". (2010): http://europepmc.org/abstract/PMC/PMC3255063.
  72. Maia CJ; Vaz CV; Peres CG; Santos CR; Socorro S. "Regucalcin, a calcium-binding protein, is a new target gene in human prostate cancer?". (2010): http://europepmc.org/abstract/PMC/PMC3255008.
  73. Rato, L.; Socorro, S.; Cavaco, J.E.B.; Oliveira, P.F.. "Tubular fluid secretion in the seminiferous epithelium: Ion transporters and aquaporins in sertoli cells". Journal of Membrane Biology 236 2 (2010): 215-224. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650212931&partnerID=MN8TOARS.
    10.1007/s00232-010-9294-x
  74. Cavaco, J.E.B.; Laurentino, S.S.; Barros, A.; Sousa, M.; Socorro, S.. "Estrogen receptors a and ß in human testis: Both isoforms are expressed". Systems Biology in Reproductive Medicine 55 4 (2009): 137-144. http://www.scopus.com/inward/record.url?eid=2-s2.0-72949111982&partnerID=MN8TOARS.
    10.3109/19396360902855733
  75. Pinto, P.I.S.; Estêvão, M.D.; Redruello, B.; Socorro, S.M.; Canário, A.V.M.; Power, D.M.. "Immunohistochemical detection of estrogen receptors in fish scales". General and Comparative Endocrinology 160 1 (2009): 19-29. http://www.scopus.com/inward/record.url?eid=2-s2.0-57649221909&partnerID=MN8TOARS.
    10.1016/j.ygcen.2008.10.011
  76. Alves, C.H.; Gonçalves, I.; Socorro, S.; Baltazar, G.; Quintela, T.; Santos, C.R.A.. "Androgen receptor is expressed in murine choroid plexus and downregulated by 5a-Dihydrotestosterone in male and female mice". Journal of Molecular Neuroscience 38 1 (2009): 41-49. http://www.scopus.com/inward/record.url?eid=2-s2.0-68949213641&partnerID=MN8TOARS.
    10.1007/s12031-008-9157-4
  77. Maia, C.; Santos, C.; Schmitt, F.; Socorro, S.. "Regucalcin is under-expressed in human breast and prostate cancers: Effect of sex steroid hormones". Journal of Cellular Biochemistry 107 4 (2009): 667-676. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650087642&partnerID=MN8TOARS.
    10.1002/jcb.22158
  78. Maia, C.J.B.; Santos, C.R.; Schmitt, F.; Socorro, S.. "Regucalcin is expressed in rat mammary gland and prostate and down-regulated by 17ß-estradiol". Molecular and Cellular Biochemistry 311 1-2 (2008): 81-86. http://www.scopus.com/inward/record.url?eid=2-s2.0-41349096904&partnerID=MN8TOARS.
    10.1007/s11010-007-9697-x
  79. Maia, C.J.B.; Socorro, S.; Schmitt, F.; Santos, C.R.A.. "STEAP1 is over-expressed in breast cancer and down-regulated by 17ß-estradiol in MCF-7 cells and in the rat mammary gland". Endocrine 34 1-3 (2008): 108-116. http://www.scopus.com/inward/record.url?eid=2-s2.0-65449116921&partnerID=MN8TOARS.
    10.1007/s12020-008-9113-7
  80. Maia, C.J.B.; Socorro, S.; Schmitt, F.; Santos, C.R.A.. "Characterization of oligoadenylate synthetase-1 expression in rat mammary gland and prostate: Effects of 17ß-estradiol on the regulation of OAS1g in both tissues". Molecular and Cellular Biochemistry 314 1-2 (2008): 113-121. http://www.scopus.com/inward/record.url?eid=2-s2.0-45449097052&partnerID=MN8TOARS.
    10.1007/s11010-008-9771-z
  81. Gonçalves, I.; Alves, C.H.; Quintela, T.; Baltazar, G.; Socorro, S.; Saraiva, M.J.; Abreu, R.; Santos, C.R.A.. "Transthyretin is up-regulated by sex hormones in mice liver". Molecular and Cellular Biochemistry 317 1-2 (2008): 137-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-53149110036&partnerID=MN8TOARS.
    10.1007/s11010-008-9841-2
  82. Socorro, S.; Martins, R.S.; Deloffre, L.; Mylonas, C.C.; Canario, A.V.M.. "A cDNA for European sea bass (Dicentrachus labrax) 11ß-hydroxylase: Gene expression during the thermosensitive period and gonadogenesis". General and Comparative Endocrinology 150 1 (2007): 164-173. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845192413&partnerID=MN8TOARS.
    10.1016/j.ygcen.2006.07.018
  83. Moutou, K.A.; Socorro, S.; Power, D.M.; Mamuris, Z.; Canario, A.V.M.. "Molecular cloning and sequence of gilthead sea bream (Sparus aurata) a-skeletal actin: Tissue and developmental expression". Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology 130 1 (2001): 13-21. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034935045&partnerID=MN8TOARS.
    10.1016/S1096-4959(01)00381-5
  84. Socorro, S.; Power, D.M.; Olsson, P.-E.; Canario, A.V.M.. "Two estrogen receptors expressed in the teleost fish, sparus aurata: cDNA cloning, characterization and tissue distribution". Journal of Endocrinology 166 2 (2000): 293-306. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033838723&partnerID=MN8TOARS.
Capítulo de livro
  1. Rocha, Sandra M; Barroca-Ferreira, Jorge; Passarinha, Luís A; Socorro, Sílvia; Maia, Cláudio J. "The Usefulness of STEAP Proteins in Prostate Cancer Clinical Practice". In Prostate Cancer, 139-154. Exon Publications, 2021.
    Publicado • 10.36255/exonpublications.prostatecancer.steap.2021
  2. Fonseca, Lara; Correia, Sara; Vaz, Cátia; Socorro, Sílvia. "The relationship of calcium-binding protein regucalcin with cancer and mammalian reproduction". In Advances in Comparative Endocrinology. Association Ibérica de Endocrinologia Comparada (AIEC), 2020.
  3. Sara Correia; Pillai, H; Silva. AMS; Santos, VM; Socorro, Sílvia. "The horizons of regucalcin in male reproduction.". In Regucalcin: Metabolic Regulation and Disease. Nova Science Publishers, Inc,, 2019.
    Publicado
  4. Figueira, Marília I.; Cardoso, Henrique J.; Socorro, Sílvia. "The Role of GPER Signaling in Carcinogenesis: A Focus on Prostate Cancer". In Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs, 59-117. Springer International Publishing, 2018.
    Publicado • 10.1007/978-3-319-71553-7_5
  5. Cavaco, J.E.; Laurentino, S.; Correia, S.; Pinto, P.; Socorro, S.. "Naturally occurring androgen receptor splice variants: Impact on androgen signaling pathways". 2014.
  6. Pinto, P.; Estêvão, M.D.; Socorro, S.. "Androgen receptors in non-mammalian vertebrates: Structure and function". In Androgen Receptor: Structural Biology, Genetics and Molecular Defects. 2014.
  7. Vaz, C.V.; Alves, M.G.; Marques, R.; Oliveira, P.F.; Maia, C.J.; Socorro, S.. "Glucose uptake and androgen responsiveness of prostate cancer cells". 2013.
  8. Dias, T.R.; Alves, M.G.; Neuhaus-Oliveira, A.; Socorro, S.; Silva, B.M.; Oliveira, P.F.. "Implications of diabetes on sperm glucose uptake and metabolism". 2013.
  9. Gomes, IM; Vaz, C.V.; Rodrigues, D; Rocha, SM; Socorro, Sílvia; Santos, CR; Maia CJ. "Estrogens and prostate cancer". In Estradiol: synthesis, Health Effects and Drug Interactions. New York, Estados Unidos: Nova Science Publishers, Inc, 2013.
    Publicado
  10. Rato, L.; Alves, M.G.; Socorro, S.; Cavaco, J.E.; Oliveira, P.F.. "Blood testis barrier: How does the seminiferous epithelium feeds the developing germ cells?". 2012.
Edição de livro
  1. Socorro, S.. Androgen receptor: Structural biology, genetics and molecular defects. 2014.
    Publicado
Livro
  1. Socorro, S.. Preface. 2014.
Poster em conferência
  1. Feijó, Mariana; Casanova, César; Fonseca, Lara R. S.; Kiss-Toth, Endre; Correia, Sara; Socorro, Sílvia. "Periprostatic adipose tissue exposed to the endocrine disruptor tributyltin changes the plasticity of human prostate cells towards a cancer progression-phenotype". Trabalho apresentado em EACR Virtual Conference on Signaling Circuits in Cancer, 2024.
  2. Fonseca L. R. S.; Feijó, Mariana; Pereira BJ; Rabaça C; Figueira MI; Laurentino, Sandra; Palmeira-de-Oliveira, A.; Socorro, Sílvia. "Escherichia coli ¿bioactive metabolites¿ modulate prostate cancer cells¿ plasticity altering survival, oxidative stress and metabolism". Trabalho apresentado em EACR Virtual Conference on Signaling Circuits in Cancer, 2024.
  3. Fonseca L. R. S.; Feijó, Mariana; Bruno Jorge Pereira; Carlos Rabaça; Figueira MI 881D-B823-72F5; Laurentino, Sandra; Palmeira-de-Oliveira, A.; Socorro, Sílvia. "Escherichia coli "bioactive metabolites" modulate human prostate cells fate, oxidative stress and metabolic reprogramming". Trabalho apresentado em III ASPIC-ASEICA International Meeting, 2023.
  4. Samuel Dinis; Diogo Ferreira; João L. Serrano; Cátia Vaz; Socorro, Sílvia; Silvestre, Samuel; Almeida, Paulo. "(Thio)barbiturates and fatty acids hybrids against prostate cancer: Synthesis, antiproliferative activity and inhibition of fatty acids intake". Trabalho apresentado em XXVIII Encontro Nacional da Sociedade Portuguesa de Química, 2023.
  5. Samuel Dinis; Diogo Ferreira; João L. Serrano; Cátia vaz; Socorro, Sílvia; Almeida, Paulo; Silvestre, Samuel. "Targeting prostate cancer by (thio)barbiturates and fatty acids hybrids: from synthesis and antiproliferative activity to inhibition of lipid intake". Trabalho apresentado em XVIII International CICS-UBI Symposium, 2023.
  6. Duarte, Filipa; Feijó, Mariana; Luís, Ângelo; Socorro, Sílvia; Maia, Cláudio J. B.; Correia, Sara. "Unveiling the preventive role of propolis facing oxidative damage in spermatogonial cells". Trabalho apresentado em XVIII International CICS-UBI Symposium, 2023.
  7. Bordadágua, Mariana; Feijó, Mariana; Socorro, Sílvia; Correia, Sara. "The impact of the endocrine disruptor methoxychlor in the glycolytic metabolism of Sertoli cells". Trabalho apresentado em XVIII International CICS-UBI Symposium, 2023.
  8. Mariana G. Veiga; Fonseca L. R. S.; Socorro, Sílvia. "Actions of the inflammatory agent lipopolysaccharide targeting energy metabolism in prostate cancer cells". Trabalho apresentado em XVIII International CICS-UBI Symposium, 2023.
  9. Carreira RJP; Fonseca L. R. S.; Figueira MI; Socorro, Sílvia. "Unravelling the relationship between the g protein-coupled estrogen receptor and the calciumbinding protein regucalcin in prostate cancer". Trabalho apresentado em XVIII International CICS-UBI Symposium, 2023.
  10. Feijó, Mariana; Casanova, César; Fonseca, Lara R. S.; Kiss-Toth, Endre; Correia, Sara; Socorro, Sílvia. "Periprostatic adipose tissue is a target of the obesogen tributyltin empowering its protumorigenic actions". Trabalho apresentado em EACR 2023 International Congress, 2023.
  11. Feijó, Mariana; Casanova, César; Fonseca L. R. S.; Kiss-Toth, Endre; Correia, Sara; Socorro, Sílvia. "The obesogen tributyltin programs periprostatic adipose tissue to a cancer driven phenotype". Trabalho apresentado em III ASPIC-ASEICA International Meeting, 2023.
  12. Tavares, Daniel; Feijó, Mariana; Fonseca, Lara; Sousa, Ana Catarina; Correia, Sara; Socorro, Sílvia. "Efeito do desregulador endócrino vinclozolina no metabolismo glicolítico do epidídimo". Trabalho apresentado em Reunião Ibérica de Andrologia, Medicina Sexual e Reprodução, Évora, 2022.
  13. Raposo, Joana; Feijó, Mariana; Maia, Cláudio J. B.; Socorro, Sílvia; Tomaz, Cândida; Correia, Sara. "Efeito do desregulador endócrino metoxicloro em células espermatogoniais". Trabalho apresentado em XVI Reunião Ibérica de Andrologia, Medicina Sexual e Reprodução, Évora, 2022.
  14. Raposo, Joana; Feijó, Mariana; Maia, Cláudio J. B.; Socorro, Sílvia; Tomaz, Cândida; Correia, Sara. "The impact of the endocrine disruptor methoxychlor on spermatogonial survival". Trabalho apresentado em XVII International CICS-UBI Symposium, Covilhã, 2022.
  15. Feijó, Mariana; Fonseca, Lara; A Brás, Luís; Kiss-Toth, Endre; Correia, Sara; Socorro, Sílvia. "Deregulation of periprostatic adipose tissue induced by the obesogen tributyltion: a driven force in tumorigenesis?". Trabalho apresentado em XVII International CICS-UBI Symposium, Covilhã, 2022.
  16. Figueira, Marília; Cardoso, Henrique; Carvalho, Tiago; Feijó, Mariana; Correia, Sara; Oliveira dos Santos, Adriana; Socorro, Sílvia. "G protein-coupled estrogen receptor reduces prostate cancer cells growth through cell cycle arrest and controls their invasive capabilities". Trabalho apresentado em II ASPIC-ASEICA International Meeting - Current Trends in Precision Medicine in Cancer, 2021.
  17. Fonseca, Lara; Figueira, Marília; Feijó, Mariana; Cavaco, José Eduardo; Cardoso, Henrique; Vaz, Cátia V; Socorro, Sílvia. "Deregulated expression of calcium-binding protein regucalcin and progression of prostate cancer: A role in prognosis?". Trabalho apresentado em II ASPIC-ASEICA International Meeting - Current Trends in Precision Medicine in Cancer, 2021.
  18. Silva, Carla; Feijó, Mariana; Fonseca, Lara; Sousa, Ana Catarina; Socorro, Sílvia; Correia, Sara. "The epididymis as a target of endocrine disruption: effect on calcium homeostasis". Trabalho apresentado em XVI Annual Cics-Ubi Symposium, Covilhã, 2021.
  19. Figueira MI; Cardoso, HJ; Carvalho, TMA; Socorro, Sílvia. "G protein-coupled estrogen receptor controls the migratory and invasive properties of human prostate cancer cells". Trabalho apresentado em 27 th Congress of the European Association for Cancer Research. EACR 2021 Virtual Congress - Innovative Cancer Science: Better Outcomes Through Research., 2021.
  20. Fonseca LRS; Figueira MI; Feijó, Mariana; Brás LP; Serra CMD; Cavaco, EJ; Cardoso, HJ; Vaz, CV; Socorro, Sílvia. "A multifunctional calcium-binding protein with a role in preventing prostate cancer development and in its monitorization?". Trabalho apresentado em 27 th Congress of the European Association for Cancer Research. EACR 2021 Virtual Congress - Innovative Cancer Science: Better Outcomes Through Research, 2021.
  21. Fonseca, Lara; Figueira, Marília; Feijó, Mariana; Brás, Luís; Serra, Catarina; Cavaco, José Eduardo; Cardoso, Henrique; Vaz, Cátia; Socorro, Sílvia. "Regucalcin: A multifunctional calcium-binding protein with a role in preventing prostate cancer development and in its monitorization?". Trabalho apresentado em EACR 2021 Virtual Congress: Innovative Cancer Science: Better Outcomes Through Research, 2021.
  22. Correia, Sara; Feijó, Mariana; Cavaco, José Eduardo; Ramalho-Santos, João; van Pelt, Ans; Socorro, Sílvia. "Effects of the endocrine disruptor methoxychlor in spermatogonial stem cells: a protective role of regucalcin?". Trabalho apresentado em 2nd Health and Well-Being Intervention International Congress, 2021.
  23. Fonseca LRS; Figueira MI; Brás LP; Serra CMD; Cavaco, EJ; Cardoso, HJ; Vaz, CV; Socorro, Sílvia. "Downregulated expression of calcium-binding protein regucalcin correlates with prostate cancer development and aggressiveness". Trabalho apresentado em Annual International (bio)Medical Students (AIMS) Meeting, 2021.
  24. Martins, Roberta; Feijó, Mariana; Socorro, Sílvia; Correia, Sara. "Tert-butyl hydroperoxide-induced disruption of the testicular glycolytic metabolism and the protective effect of regucalcin". Trabalho apresentado em XV Annual Cics-Ubi Symposium, Covilhã, 2020.
  25. Feijó, Mariana; Castanheira, Mariana; Cavaco, Eduardo; Ramalho-Santos, João; van Pelt, Ans; Socorro, Sílvia; Correia, Sara. "Endocrine disruptors with xenoestrogenic and antiandrogenic activity affect the glycolytic metabolism of spermatogonial stem cells". Trabalho apresentado em XV Annual Cics-Ubi Symposium, Covilhã, 2020.
  26. Fonseca LRS; Cardoso, HJ; Vaz, CV; Socorro, Sílvia. "Loss of regucalcin protein contributes for prostate cancer development and aggressiveness". Trabalho apresentado em Cancer Biology: From Basic to Translational Research, 2020.
  27. Brás, L; Cardoso, HJ; Serra, C; Lara Fonseca; Vaz, CV; Socorro, Sílvia. "Tributyltin stimulates the glycolytic and lipid metabolism of human neoplastic prostate cancer cells: a missing link between obesity and prostate cancer?". Trabalho apresentado em III International Congress in Health Sciences Research towards innovation and entrepreneurship: Trends in Aging and Cancer, 2019.
  28. Vaz, Cátia; Silva, Gonçalo; Catalão, Beatriz; Ferreira, Susana; Cardoso, Henrique; Duarte, Ana Paula; Socorro, Sílvia. "The role of sweet cherry extract shaping the hallmarks of cancer in human prostate cells". Trabalho apresentado em III International Congress in Health Sciences Research towards innovation and entrepreneurship, 2019.
  29. Silva, AMS; Socorro, Sílvia; Hurtado de Llera, A; Vaz, CV; Correia, Sara#; Maia, CJ#. "Regucalcin protein alleviates ageing-related changes in male reproductive function. #contributed equally as senior authors". Trabalho apresentado em III International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship – Trends in Aging and Cancer (HSR-UBI 2019), 2019.
  30. Rocha, Sandra Moreira; Santos, F.M.; Passarinha LA; Socorro, Sílvia; Maia, Cláudio J. B.; Passarinha, Luís. "Proteomic analysis of human prostate cancer LNCaP cells upon STEAP1 knockdown.". Trabalho apresentado em III International Congress in Health Sciences Research towards innovation and entrepreneurship, 2019.
  31. Casimiro, neusa; Vitória, Paulo D; Socorro, Sílvia. "An exploratory study on psychosocial factors related to women infertility". Trabalho apresentado em 03rd Infectious Diseases in Obstetrics and Gynecology (ISIDOG) Congress, Porto, Portugal, 2019.
  32. Casimiro, neusa; Vitória, Paulo D; Socorro, Sílvia. "Characterization of gynecology consultation at a public hospital in Cabinda (Angola)". Trabalho apresentado em 03rd Infectious Diseases in Obstetrics and Gynecology (ISIDOG) Congress, Porto, Portugal, 2019.
  33. Vaz, CV; Silva, GR; Carvalho, TMA; Brás, L; Lara Fonseca; Figueira, MI; Cardoso, HJ; Duarte, AP; Socorro, Sílvia. "Human neoplastic and non-neoplastic prostate cells are sensitive to metabolic (de)regulation induced by endocrine disrupting chemicals and dietary factors". Trabalho apresentado em 26th MEETING OF THE EAU SECTION OF UROLOGICAL RESEARCH (ESUR), 2019.
  34. Figueira, MI; Cardoso, HJ; Socorro, Sílvia. "G protein-coupled estrogen receptor activation changes the metabolic profile of prostate cancer cells". Trabalho apresentado em 2ND FEBS ADVANCED LECTURE COURSE ON ONCOMETABOLISM, 2019.
  35. Casimiro, neusa; Vitória, Paulo D; Socorro, Sílvia. "Estudo exploratório sobre a qualidade de vida de mulheres com infertilidade". Trabalho apresentado em XIV CICS-UBI Annual Symposium,, 2019.
  36. Figueira, MI; Cardoso, HJ; Carvalho, TMA; Henrique, Rui; Cláudio Maia; Socorro, Sílvia. "G protein-coupled estrogen receptor is downregulated in aggressive stages of prostate cancer: preliminary insight in reversion of castration-resistance". Trabalho apresentado em XIV ANNUAL CICS-UBI SYMPOSIUM, 2019.
  37. Martins, Roberta; Silva, AM; Feijó, Mariana; Socorro, Sílvia; Correia, Sara. "Metabolic Cooperation in the Seminiferous Tubules of Transgenic Rats Overexpressing Regucalcin". Trabalho apresentado em XIV CICS-UBI Annual Symposyum, Covilhã, 2019.
  38. Carvalho, Tiago; Monteiro, Joana; Cardoso, Henrique; Figueira, Marília; Vaz, Cátia; Socorro, Sílvia. "Estrogens and environmental "estrogen-like" substances modulate the glycolytic metabolism of human prostate cancer cells". Trabalho apresentado em 1st Portuguese Symposium on Research and Innovations in Urology, 2018.
  39. Carvalho, TMA; Cardoso, HJ; Figueira, MI; Vaz, CV; Socorro, Sílvia. "Effect of endocrine disruptor methoxychlor modulating the behaviour of human prostate cancer cells: are the estrogen receptors involved?". Trabalho apresentado em XIII ANNUAL CICS-UBI SYMPOSIUM, 2018.
  40. Cardoso, HJ; Figueira MI; Madureira, Patrícia Alexandra; Socorro, Sílvia. "The pivotal role of glutaminolysis in prostate cancer cells and its regulation by androgens". Trabalho apresentado em 25 th BIENNIAL CONGRESS OF THE EUROPEAN ASSOCIATION FOR CANCER RESEARCH, 2018.
  41. Figueira MI; Cardoso, HJ; Socorro, Sílvia. "G protein-coupled oestrogen receptor activation decreases prostate cancer cells viability concomitantly with altered proliferation, apoptosis, and metabolic profile". Trabalho apresentado em 25 th BIENNIAL CONGRESS OF THE EUROPEAN ASSOCIATION FOR CANCER RESEARCH, 2018.
  42. Feijó, Mariana; Cavaco, Eduardo; Ramalho-Santos, João; van Pelt, Ans; Socorro, Sílvia; Correia, Sara. "Effects of 17ß-Estradiol and Endocrine Disruptor Methoxychlor in Spermatogonial Stem Cells". Trabalho apresentado em XIII CICS-UBI Annual Symposium, Covilhã, 2018.
  43. Monteiro, Joana; Vaz, Cátia; Socorro, Sílvia. "17ß-Estradiol Stimulates the Glycolytic Metabolism of LNCaP Prostate Cancer Cells". Trabalho apresentado em 3th ASPIC International Congress, 2018.
  44. Carvalho, TMA; Cardoso, HJ; Figueira, MI; Vaz, CV; Socorro, Sílvia. "The endocrine disruptor methoxychlor modulates the apoptotic pathways and glycolytic metabolism in human prostate cancer cells". Trabalho apresentado em 3th ASPIC INTERNATIONAL CONGRESS, 2018.
  45. Cardoso, HJ; Vaz, CV; Carvalho, TMA; Figueira, MI; Socorro, Sílvia. "Castrate-resistant prostate cancer cells display differential response to imatinib dependently on glycaemic conditions". Trabalho apresentado em 3th ASPIC INTERNATIONAL CONGRESS, 2018.
  46. Figueira, MI; Cardoso, HJ; Silvestre, S; Socorro, Sílvia. "Anti-tumoral effects of diosgenin in prostate cancer cells: insights from cell proliferation, apoptosis, and metabolism". Trabalho apresentado em 3th ASPIC INTERNATIONAL CONGRESS, 2018.
  47. Correia, Sara; Cavaco, J.E.B.; Socorro, Sílvia. "Hyperestrogenism, germ cell apoptosis and male infertility: exploring the link". Trabalho apresentado em ESAU Oporto Meeting, Joint Meeting ESAU-Portuguese Society of Andrology, 2018.
  48. Correia, Sara; Feijó, Mariana; Ramalho-Santos, João; van Pelt, Ans; Socorro, Sílvia. "Efeitos dos Disruptores Endócrinos nas Espermatogónias Estaminais: onde se enquadra o papel protetor da Regucalcina?". Trabalho apresentado em XVI National Congress of Portuguese Society of Andrology, Sexual Medicine and Reproduction, Porto, 2018.
  49. Correia, Sara; Feijó, Mariana; Ramalho-Santos, João; van Pelt, Ans; Socorro, Sílvia. "Effect of Endocrine Disruptors in Spermatogonial Stem Cells: where does the protective role of Regucalcin fit in?". Trabalho apresentado em Joint Meeting ESAU-Portuguese Society of Andrology, Porto, 2018.
    10.5274/assbt.2011.6
  50. Silva, AMS; Correia, Sara; Vaz, CV; Socorro, Sílvia; Maia, CJ. "Regucalcin overexpression prevents the age-associated decline of sperm quality". Trabalho apresentado em II International Congress in Health Sciences Research Towards Innovation and Entrepreneurship - Trends in Biotechnology for Biomedical Applications, 2017.
  51. Marques, R; Vaz, Cátia; Maia CJ; Socorro, Sílvia. "Regucalcin in hormone-dependent cancers: towards a candidate tumour supressor gene?". Trabalho apresentado em EACR24th From basic research to precision medicine, 2016.
  52. Cardoso, HJ; Figueira, MI; Vaz, CV; Socorro, Sílvia. "The androgens and glutaminolysis in prostate cancer: a new therapeutic approach". Trabalho apresentado em 2nd ASPIC INTERNATIONAL CONGRESS, 2016.
  53. Figueira, MI; Cardoso, HJ; Socorro, Sílvia. "GPER is differentially expressed in prostate cancer cell lines". Trabalho apresentado em 2nd ASPIC INTERNATIONAL CONGRESS, 2016.
  54. Marques, R; Vaz, CV; Maia CJ; Socorro, Sílvia. "Role of the androgen-target gene regucalcin in breast cancer and prostate physiology". Trabalho apresentado em 2nd ASPIC International Congress, 2016.
  55. Marques, R; Vaz, CV; Gomes, IM; Cairrão ME; Verde JI; Maia CJ; Socorro, Sílvia. "Abstract 1989: The effect of resveratrol combined with DFMO or DenSpm on MCF-7 breast cancer cells and MCF-10a non-cancerous cells". Trabalho apresentado em . XVIII Congress of the Portuguese Biochemical Society, 2014.
    10.1158/1538-7445.am2012-1989
  56. Correia, Sara; Cavaco, JEB; Socorro, Sílvia. "Regucalcin protein protects against oxidative stress in rat testis and epididymis". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, 2014.
  57. Marques, R; Vaz, CV; Maia CJ; Gomes M,; Gama A,; Alves G,; Santos CR,; Schmitt F,; Socorro, Sílvia. "Regucalcin, as a protective molecule in breast cancer: clinicohistopathological and in vivo evidences". Trabalho apresentado em 1st ASPIC International Congress, 2014.
  58. Vaz, CV; Maia, CJ; Marques, Ricardo; Gomes, IM; Correia, Sara; Alves, MG; Cavaco, JEB; Oliveira, PF; Socorro, Sílvia. "Regucalcin, a new androgen target gene involved in the regulation of prostate cell growth". Trabalho apresentado em 1st ASPIC International Congress, 2014.
  59. Figueira, MI; Correia, Sara; Vaz, CV; Cardoso, HJ; Gomes, IM; Marques, Ricardo; Maia, CJ; Socorro, Sílvia. "The estrogenic regulation of stem cell factor (SCF) and c-KIT in rat prostate supports the protective role of estrogens in prostate cancer". Trabalho apresentado em 1st ASPIC International Congress, 2014.
  60. Cardoso, HJ; Vaz, CV; Correia, Sara; Figueira, MI; Marques, Ricardo; Maia, CJ; Socorro, Sílvia. "Paradoxical and contradictory effects of imatinib in two cell line models of prostate cancer". Trabalho apresentado em 1st ASPIC International Congress, 2014.
  61. Correia, Sara; Alves, MR; Martins, AD; Cavaco, JEB; Oliveira, PF; Socorro, Sílvia. "Effect of 17ß-estradiol on germ cell apoptosis by modulating the expression of SCF/c-kit, FasL/FasR and regucalcin". Trabalho apresentado em 16th ECE, 2014.
  62. Bernardino, Raquel L.; Martins, Ana; Jesus, Tito T; Sá, Rosália; Sousa, Mário; Socorro, Sílvia; Alves, Marco G; Oliveira, Pedro F.. "Regulation by estrogens of bicarbonate secretion mechanisms in Sertoli cells". Trabalho apresentado em XXVII IUPS Congress 2013, 2013.
  63. Correia, Sara; Alves, M; Oliveira, PF; Cavaco, JEB; Socorro, Sílvia. "Regucalcin, an apoptosis regulator in spermatogenesis?". Trabalho apresentado em 38th FEBS Congress: Mechanisms in Biology, 2013.
  64. Alves, MR; Correia, Sara; Laurentino, S.; Cavaco, JEB; Oliveira, PF; Socorro, Sílvia. "Genes under estrogenic control in the testis: impact on apoptosis and male fertility". Trabalho apresentado em XXXVIII Jornadas Portuguesas de Genética, 2013.
  65. Bernardino, Raquel L.; Martins, Ana D; Jesus, Tito T.; Sá, Rosália; Sousa, Mário; Socorro, Sílvia; Alves, Marco G.; Oliveira, Pedro F.. "Regulation by estrogens of bicarbonate secretion mechanisms in Sertoli cell". Trabalho apresentado em 37th IUPS, 2013.
  66. Martins, Ana; Simões, Vera L; Alves, Marco G; Cavaco, José E; Socorro, Sílvia; Oliveira, Pedro F.. "Hormonal Regulation of Na+-H+ Exchanger 3 (NHE-3) in Sertoli Cells: A Possible Role for Estrogens in Spermatogenesis.". Trabalho apresentado em 7th European Congress of Andrology, 2012.
  67. Correia, Sara; Oliveira, PF; Lopes, G; Cavaco, JEB; Socorro, Sílvia. "The role of Regucalcin (RGN) on epididymal sperm parameters: evidences from RGN-transgenic rats". Trabalho apresentado em Society for Reproduction and Fertility Conference, 2012.
  68. Laurentino, S.; Correia, Sara; Maia, CJ; Cavaco, JEB; Socorro, Sílvia. "Regucalcin, a calcium-binding protein, as a new sex steroid target gene in rat testis". Trabalho apresentado em 11th International EMBL PhD Student Symposium, 2009.
Resumo em conferência
  1. Casanova, César; Feijó, Mariana; Correia, Sara; Socorro, Sílvia. "Periprostatic adipose tissue as a target of the obesogen tributyltin: Implications for prostate tumorigenesis". Trabalho apresentado em XVIII International CICS-UBI Symposium, Covilhã, 2023.
  2. Feijó, Mariana; Cavaco, JEB; Ramalho-Santos, João; van Pelt, AMM; Socorro, Sílvia; Correia, Sara. "Spermatogonial stem cells and estrogens: what if regucalcin is added to the equation?". Trabalho apresentado em 2nd International Congress of Health and Well-being intervention, 2021.
  3. Cardoso, HJ; Figueira, MI; Carvalho, TMA; Vaz, CV; Madureira, Patrícia Alexandra; Socorro, Sílvia. "LDL-cholesterol enriched environment favours prostate cancer cells viability, proliferation, and migration dependently on androgens". Trabalho apresentado em 2ND FEBS ADVANCED LECTURE COURSE ON ONCOMETABOLISM, Luso, 2019.
    Publicado
  4. Cardoso, HJ; Figueira, MI; Carvalho, TMA; Vaz, CV; Madureira, Patrícia Alexandra; Socorro, Sílvia. "LDL-cholesterol effects modulating prostate cancer cells fate in the interplay with androgens". Trabalho apresentado em XIV ANNUAL CICS-UBI SYMPOSIUM, Covilhã, 2019.
    Publicado
  5. Martins, RVL; Silva, AMS; Socorro, Sílvia; Correia, Sara. "The protective effect of regucalcin against tert-butyl hydroperoxide-induced disruption of testicular glycolytic metabolism". Trabalho apresentado em III International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship – Trends in Aging and Cancer (HSR-UBI 2019), 2019.
  6. Silva, AMS; Correia, Sara; Vaz, CV; Socorro, Sílvia; Maia, CJ. "Transgenic overexpression of regucalcin protein attenuates ageing-associated changes in the male reproductive function.". Trabalho apresentado em XIV Annual CICS-UBI Symposium, 2019.
  7. Vaz, CV; Serra, Catarina; Brás, L; Fonseca, L; Cardoso, HJ; Socorro, Sílvia. "The obesogen tributyltin deregulates glycolytic and lipid metabolism of human neoplastic and non-neoplastic prostate cells". Trabalho apresentado em 2ND FEBS ADVANCED LECTURE COURSE ON ONCOMETABOLISM, 2019.
  8. Cardoso, HJ; Vaz, CV; Carvalho, TMA; Figueira, MI; Socorro, Sílvia. "Imatinib modulates proliferation and apoptosis of the highly glycolytic castrate-resistant prostate cancer cells: effect of a glucose-enriched environment". Trabalho apresentado em 1st PORTUGUESE SYMPOSIUM ON RESEARCH AND INOVATIONS IN UROLOGY, Lisboa, 2018.
    Publicado
  9. Figueira, MI; Cardoso, HJ; Socorro, Sílvia. "G protein-coupled estrogen receptor effects modulating the behaviour of prostate cancer cells". Trabalho apresentado em XIII ANNUAL CICS-UBI SYMPOSIUM, COVILHÃ, 2018.
    Publicado
  10. Cardoso, HJ; Figueira, MI; Madureira, Patrícia Alexandra; Socorro, Sílvia. "The multiple faces of prostate cancer metabolism: the special role of androgens". Trabalho apresentado em XIII ANNUAL CICS-UBI SYPOSIUM, Covilhã, 2018.
    Publicado
  11. Santos, VM; Correia, Sara; Pinto, P.; Socorro, Sílvia. "The testicular transcriptome of transgenic rats overexpressing regucalcin (RGN): an insight into RGN role in spermatogenesis". Trabalho apresentado em XIII Annual CICS-UBI Symposium,, 2018.
  12. Carvalho, TMA; Cardoso, HJ; Figueira, MI; Vaz, CV; Socorro, Sílvia. "Methoxychlor modulates cell viability and glycolytic metabolism in human prostate cancer cells". Trabalho apresentado em XII ANNUAL CICS-UBI SYMPOSIUM, Covilhã, 2017.
    Publicado
  13. Marques, R; Vaz, Cátia; Maia CJ; Socorro, Sílvia. "Regucalcin in hormone-dependent cancers: towards a candidate tumour suppressor gene?". Trabalho apresentado em EACR24th From basic research to precision medicine, Manchester, 2016.
    10.1016/S0959-8049(16)61149-8
  14. Espínola, L; Correia, Sara; Socorro, Sílvia. "Estrogens as modulators of calcium and water influxes in the Epididymis". Trabalho apresentado em XI Annual CICS-UBI Symposium, 2016.
  15. Coelho, A; Correia, Sara; Socorro, Sílvia; Almeida, P. "Development of new aromatase inhibitors analogues of letrozole: perspectives for treatment of male infertility". Trabalho apresentado em . XI Annual CICS-UBI Symposium, 2016.
  16. Cardoso, HJ; Vaz, CV; Figueira, MI; Socorro, Sílvia. "Cell line models of hormone-refractory prostate cancer display differential response to imatinib dependently on the glycolytic environment". Trabalho apresentado em I Congress in Health Sciences Research: Towards Innovation and Entrepreneurship Trends in Endocrinology and Neurosciences, Covilhã, 2015.
    Publicado
  17. Cardoso, HJ; Vaz, CV; Figueira, MI; Socorro, Sílvia. "Hyperglycemia and hypoglycemia underlie differential responses to imatinib in cell line models of hormone-refractory prostate cancer". Trabalho apresentado em X ANNUAL CICS-UBI SYMPOSIUM, Covilhã, 2015.
    Publicado
  18. Bernardino, Raquel L.; Martins, Ana D; Costa, Ana Raquel; Silva, Joaquina; Barros, Alberto; Sá, Rosália; Alves, Marco Gouveia; et al. "Estrogenic regulation of Na+-dependent bicarbonate transporters from SLC4 family in human Sertoli Cells.". Trabalho apresentado em FEBS, 2015.
    Publicado • 10.1007/s11010-015-2481-4
  19. Silva, AMS#; Correia, Sara#; Casalta-Lopes, J; Mamede, AC; Cavaco, JE; Botelho, MF; Mais, CJ; Socorro, Sílvia. "The androgen-target gene regucalcin as an apoptosis modulator in irradiated rat testis #both authors contributed equally". Trabalho apresentado em I Congress in Health Sciences Research - Towards Innovation and Entrepreneurship Trends in Endocrinology and Neurosciences, 2015.
  20. Figueira, MI; Correia, Sara; Vaz, CV; Cardoso, HJ; Gomes, IM; Marques, Ricardo; Maia, CJ; Socorro, Sílvia. "Estrogenic actions in the prostate: are the stem cell factor (SCF) and c-KIT receptor involved?". Trabalho apresentado em I Congress in Health Sciences Research -Towards Innovation and Entrepreneurship Trends in Endocrinology and Neurosciences, 2015.
  21. Silva, AMS#; Correia, Sara#; Casalta-Lopes, JE; Mamede, AC; Cavaco, JEB; Botelho, MF; Maia, CJ; Socorro, Sílvia. "The protective effect of regucalcin against radiation-induced testicular damage #both authors contributed equally". Trabalho apresentado em X Annual CICS-UBI Symposium, 2015.
  22. Marques, Ricardo; Vaz, Cátia; Alves, M.G.; Moreira, PI; Oliveira PF; Cavaco, J.E.; Maia CJ; Socorro, Sílvia. "Androgens regulate gene expression of glucose transporters and glycolytic enzymes in prostate cancer cells". Trabalho apresentado em 16th European Congress of Endocrinology, Wroclaw, 2014.
    10.1530/endoabs.35.P571
  23. Marques, Ricardo; Vaz, Cátia V.; Gomes, Inês M; Cairrao, E.; Verde, I.; Maia, C. J.; Socorro, Sílvia; Maia CJ. "L-type Ca2+ channels in breast cancer MCF-7 cells: identification and regulation by androgens". Trabalho apresentado em FEBS-EMBO Congress, Paris, France, 2014.
    Publicado
  24. Marques, Ricardo; Vaz, Cátia V.; Maia, C. J.; Gomes, M; Gama, A; Alves, G; Santos, C. R.; Schmitt, Fernando; Socorro, Sílvia. "Clinicohistopathological and in vivo evidences". Trabalho apresentado em 1st ASPIC International Congress, Lisbon, Portugal, 2014.
    Publicado
  25. Maia CJ; Maia C; Vaz, Cátia V.; Marques, Ricardo; Cavaco, J. E.; Maia, C. J.; Socorro, Sílvia. "Regucalcin, a calcium (Ca2+)-binding protein with a protective role in prostate age-related diseases?". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, Coimbra, Portugal, 2014.
    Publicado
  26. Figueira, MI; Correia, Sara; Vaz, CV; Cardoso, H.J.; Gomes, IM; Marques, Ricardo; Mais, CJ; Socorro, Sílvia. "Estrogens down-regulate the stem cell factor (SCF)/c-KIT system in rat prostate: evidence of antiproliferative and apoptotic effects.". Trabalho apresentado em IX CICS-UBI Symposium, 2014.
  27. Marques, R; Vaz, CV; Maia CJ; Gama, A.; Alves, G.; Schmitt, F.; Santos, CR; Socorro, Sílvia. "Transgenic rats overexpressing Regucalcin display lower-susceptibility to develop DMBA-induced mammary gland tumors". Trabalho apresentado em 38th Federation of European Biochemical Societies Congress – Mechanisms in Biology, St. Petersburg, 2013.
    10.1111/febs.12340
  28. Marques, R; Vaz, CV; Alves MG; Oliveira PF; Maia CJ; Socorro, Sílvia; Vaz, Cátia. "Glucose Metabolism and Androgen Responsiveness of Prostate Cancer Cells". Trabalho apresentado em 38th Federation of European Biochemical Societies Congress – Mechanisms in Biology, St. Petersburg, 2013.
    https://doi.org/10.1111/febs.12340
  29. Marques, R; Vaz, CV; Maia CJ; Alves MG; Cavaco JE; Oliveira PF; Socorro, Sílvia; Alves MG,; Cavaco JE,. "Expression of Apoptosis and Cell-cycle Regulators in Rat Prostate Overexpressing Regucalcin". Trabalho apresentado em 2nd Congress of European Association for Cancer Research - from Basic Research to Personalised Cancer Treatment, Barcelona, 2012.
    10.1016/S0959-8049(12)70871-7
  30. Marques, Ricardo; Vaz, CV; Peres CG; Gomes, I.; Santos, CR; Maia CJ; Socorro, Sílvia. "Effect of Androgens on the Expression of Ca2+-binding Protein, Regucalcin, and Ca2+-channels in MCF-7 Cells". Trabalho apresentado em 22nd Congress of European Association for Cancer Research - from Basic Research to Personalised Cancer Treatment, Barcelona, 2012.
    10.1016/S0959-8049(12)70876-6
  31. Laurentino, S; Correia, Sara; Gonçalves, J; Cavaco, JEB; Oliveira, PF; Rato, L; Sousa, M; Barros, A.; Socorro, Sílvia. "New sex steroid target genes in the testis: the missing link between estrogens and apoptosis in spermatogenesis?". Trabalho apresentado em 20th World Congress on Fertility and Sterility, Munich, 2010.
  32. Correia, Sara; Laurentino, S.; Maia, CJ; Cavaco, JEB; Socorro, Sílvia. "Regucalcin, a new sex steroid target gene in Spermatogenesis?". Trabalho apresentado em IV CICS-UBI Symposium, 2009.
  33. Correia, Sara; Maia, CJ; Cavaco, JEB; Socorro, Sílvia. "Expression of Regucalcin in rat and human testis: Possible role in spermatogenesis?". Trabalho apresentado em III CICS-UBI Symposium, 2008.

Outros

Outra produção
  1. Regucalcin as a new tumor suppressor gene?. 2016. Vaz, CV; Sara Correia; Cardoso, HJ; Figueira, MI; Ricardo J Marques; Maia CJ; Socorro, Sílvia. http://www.aspic.pt/pt-pt/node/4657.
  2. Regucalcin controls prostate cell proliferation and glycolytic metabolism. 2016. Vaz, CV; Ricardo J Marques; Cardoso, HJ; Maia CJ; Socorro, Sílvia. https://atlasofscience.org/regucalcin-controls-prostate-cell-proliferation-and-glycolytic-metabolism/.
  3. Commonalities of survival strategies employed by germ and cancer cells: the case of SCF/c-KIT system. 2014. Cardoso, HJ; Figueira, MI; Sara Correia; Vaz, CV; Socorro, Sílvia. http://www.aspic.pt/pt-pt/node/2668.
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2018 - Atual Fatores psicossociais relacionados com a infertilidade feminina em Cabinda (Angola)
Coorientador
Biomedicina (Doutoramento)
Universidade da Beira Interior, Portugal
2016 - Atual TRIB1/3 modulation of androgen actions in prostate cancer
Orientador
Biomedicina (Doutoramento)
Universidade da Beira Interior, Portugal
2021 - 2025 Prostate bacteriome as a driven force in carcinogenesis: from tumour onset to therapy resistance
Orientador de Lara Raquel dos Santos Fonseca
Bioquímica (Doutoramento)
Universidade da Beira Interior, Portugal
2021 - 2025 Obesogens-induced deregulation of periprostatic adipose tissue: a driven force in the onset and progression of prostate cancer?”
Orientador
Bioquímica (Doutoramento)
Universidade da Beira Interior, Portugal
2015 - 2023/12/19 Estrogens and the G protein-coupled estrogen receptor in prostate cancer: angels or demons?
Orientador
Biomedicina (Doutoramento)
Universidade da Beira Interior, Portugal
2018 - 2023 Unrevealing the effect of STEAP1 knokdown in prostate cancer cells; from protein expression profile to clinical applications
Orientador
Biomedicina (Doutoramento)
Universidade da Beira Interior, Portugal
2015 - 2019 Prostate cancer cells metabolism on the interplay of androgenic regulation and metabolic environment
Orientador
Biomedicina (Doutoramento)
Universidade da Beira Interior, Portugal
2012 - 2016 Genética molecular do hipogonadismo hipogonadotrófico idiopático
Coorientador
Biomedicina (Doutoramento)
Universidade da Beira Interior, Portugal
2012 - 2016 Biological evidence of the protective role of regucalcin in beast cancer
Orientador
Biomedicina (Doutoramento)
Universidade da Beira Interior, Portugal
2011 - 2015 Androgens and calcium-binding protein regucalcin in the control of prostate cells metabolism and survival: implicatons in carcinogenesis
Orientador
Biomedicina (Doutoramento)
Universidade da Beira Interior, Portugal
2011 - 2014 Estrogens and Regucalcin in Testicular Apoptosis and Sperm Function: a Mather of Life and Death
Orientador
Biomedicina (Doutoramento)
Universidade da Beira Interior, Portugal
2008 - 2011 Sexual Steroid Regulation of Spermatogensis: New Actors Enter the Stage
Orientador
Biomedicina (Doutoramento)
Universidade da Beira Interior, Portugal
2005 - 2008 Novel genes differentially expressed in breast and prostate cancer: effects of sex steroid hormones
Orientador
Biomedicina (Doutoramento)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2024 Contribution to the study of prostate cancer: lifestyle influence in an animal model
Arguente
Elisabete Nascimento Gonçalves (Doutoramento)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022 Macrophage Microvesicle Production and Targeting
Arguente principal
Tagreed Shamrani (Doutoramento)
The University of Sheffield, Reino Unido
2021/07 Aggregation in Health Sciences, Biomedical Sciences
Arguente principal
Joana Lima Barbosa de Melo (Agregação)
Universidade de Coimbra Faculdade de Medicina, Portugal
2021/07 Aggregation in Biomedicine
Arguente
Liliana Inácio Bernardino (Agregação)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2021 Aromatase inhibitors in breast cancer: Drug discovery and strategies to overcome acquired resistance
Arguente principal
Tiago André Sousa Vieira Augusto (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2021 Characterization of TRIB2-mediated Drug Resistance
Arguente principal
Susana Machado (Doutoramento)
Universidade do Algarve, Portugal
2021 Investigating Tribbles 1 expression in the immune and adrenocortical cell populations of the adrenal gland under basal, inflammatory, and steroidogenic-promoting conditions
Arguente principal
Dominika Grzesik (Doutoramento)
Queen Mary University of London, Reino Unido
2020 Tribbles: the tumour microenvironment and their involvement in cancer
Arguente principal
Swapna Santosh Satam (Doutoramento)
Blackwell's University of Sheffield, Reino Unido
2019 Function and expression of the AMP-activating kinase, AMPK, in human spermatozoa
Arguente
Violeta Calle Guisado (Doutoramento)
Universidad de Extremadura, Espanha
2017 Monocarboxylate Transporters (MCTs) in breast cancer aggressiveness: therapeutic targeting and regulatory mechanisms
Arguente principal
Luísa Filipa Morais dos Santos (Doutoramento)
Universidade do Minho Escola de Medicina, Portugal
2015 Human Sperm Motility: proteins and metabolites towards the same journey’s end
Arguente principal
Carla Patrícia Rodrigues Paiva (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2014 Role of monocarboxylate transporters in prostate carcinoma
Arguente principal
Isabel Arouca Pértega-Gomes (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 DAX1 a sex determining gene in fish?
Arguente principal
Rute Sofia Tavares Martins (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007 Ciclo Hormonal Reprodutor, clonagem e expressão da enzima P450 aromatase na tilápia, Oreochromis mossambicus (Teleostei: Cichlidae)
Arguente principal
Mário António Pestana de Almeida e Cruz (Doutoramento)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2006 Diversidade, Expressão e Mecanismo de Acção do Receptor de Estrogénio na Dourada, Sparus aurata
Arguente principal
Patrícia Isabel Silvestre Pinto (Doutoramento)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2021 - 2024 Current Cell Science Bentham Science
2020 - 2024 Molecules MDPI

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2010 - 2024 Human Anatomy and Physiology II Biomedical Sciences (Licenciatura) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2010 - 2024 Biology of Reproduction Biomedical Sciences (Mestrado) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2002 - 2024 Nephrourinary and reproductive system Medicina (Mestrado integrado) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2017 - 2021 Thesis in Biomedicine 2 Biomedicina (Doutoramento) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2017 - 2021 Thesis in Biomedicine 3 Biomedicina (Doutoramento) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2011 - 2021 Project thesis Biomedicina (Doutoramento) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2010 - 2021 Endocrinology of Reproduction Biomedicina (Doutoramento) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2015 - 2017 Research methodologies Biomedicina (Doutoramento) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2009 - 2011 Mechanisms of Hormonal Action Biomedicina (Doutoramento) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2007 - 2011 Introduction to Biomedical Sciences Biomedical Sciences (Licenciatura) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2007 - 2011 Seminar Biomedical Sciences (Licenciatura) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

Membro de associação

Nome da associação Tipo de participação
2016 - Atual Sociedade Portuguesa de Andrologia
2012 - Atual ASPIC Vice-President of the Fiscal Council
2012 - Atual European Association for Cancer Research (EACR)

Tutoria

Tópico Nome do aluno
2020/09/01 - 2021/07/31 University of Algarve Alumni Mentoring Programme Ana Beatriz Oliveira
Distinções

Prémio

2022 Award Professor Alexandre Moreira Investigação in Andrology, Sexual Medicine and Reproduction 2018-2019
Sociedade Portuguesa de Andrologia, Portugal
2021 Prémio Carreira Alumni da Universidade do Algarve
Universidade do Algarve, Portugal
2018 Award Professor Alexandre Moreira Investigação in Andrology, Sexual Medicine and Reproduction 2016-2017
Sociedade Portuguesa de Andrologia, Portugal