| Artigo em conferência |
- Bicker, Joana; Alves, Gilberto; Cavaleiro, Carlos; Fortuna, Ana; Amílcar Falcão. "Identification of P-glycoprotein inhibitors
in Caco 2 cells: An in vitro screening methodology". Trabalho apresentado em 9th World Meeting on Pharmaceutics, 2014.
Aceite para publicação
- Serralheiro, Ana ; Alves, Gilberto; Fortuna, Ana; Amílcar Falcão. "Direct nose-to-brain delivery of carbamazepine after intranasal
administration to mice.". Trabalho apresentado em 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical
Technology, 2014.
|
| Artigo em jornal |
- Meirinho, Sara; Rodrigues, Márcio; Ferreira, Catarina L.; Oliveira, Rui Caetano; Fortuna, Ana; SANTOS, ADRIANA O.; Falcão,
Amílcar; Alves, Gilberto. Autor correspondente: Alves, Gilberto. "Intranasal delivery of lipid-based nanosystems as a promising
approach for brain targeting of the new-generation antiepileptic drug perampanel", International Journal of Pharmaceutics,
2022, https://doi.org/10.1016/j.ijpharm.2022.121853.
|
| Artigo em revista |
- Martins, Mariana S.; Rodrigues, Márcio; Flores-Félix, José David; Moreno, Diego A.; Garcia-Viguera, Cristina; Alves, Gilberto;
Silva, Luís R.; Gonçalves, Ana C.. Autor correspondente: Gonçalves, Ana C.. "The effect of phenolic-rich extracts of Rubus
fruticosus, R. ulmifolius and Morus nigra on oxidative stress and Caco-2 inhibition growth". Nutrients 16 9 (2024):
1361. https://www.mdpi.com/2072-6643/16/9/1361.
Publicado
- Flores-Félix, José David; Gonçalves, Ana Carolina; Meirinho, Sara; Nunes, Ana Raquel; Alves, Gilberto; Garcia-Viguera, Cristina;
Moreno, Diego A.; et al. "Differential response of blueberry to the application of bacterial inoculants to improve yield,
organoleptic qualities and concentration of bioactive compounds". Microbiological Research 278 (2024): 127544. http://dx.doi.org/10.1016/j.micres.2023.127544.
10.1016/j.micres.2023.127544
- Gonçalves, Ana C.; Falcão, Amílcar C.; Alves, Gilberto; Silva, Luís R.; Flores-Félix, José David. "Antioxidant activity of
the main phenolics found in red fruits: An in vitro and in silico study". Food Chemistry 452 (2024): 139459. https://www.sciencedirect.com/science/article/abs/pii/S0308814624011099.
Publicado
- Catarina Candeias; Jorge Gama; Márcio Rodrigues; Amílcar Falcão; Gilberto Alves. "Patients’ Characterization, Pattern of Medication
Use, and Factors Associated with Polypharmacy: A Cross-Sectional Study Focused on Eight Units of the Portuguese National Network
for Long-Term Integrated Care". Healthcare (2023): https://doi.org/10.3390/healthcare12010057.
10.3390/healthcare12010057
- Ana C. Gonçalves; Amílcar Falcão; Gilberto Alves; Luís R. Silva; José D. Flores-Félix. "Diversity of Culture Microorganisms
from Portuguese Sweet Cherries". Life (2023): https://doi.org/10.3390/life13122323.
10.3390/life13122323
- Mariana S. Martins; Ana C. Gonçalves; Gilberto Alves; Luís R. Silva. "Blackberries and Mulberries: Berries with Significant
Health-Promoting Properties". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms241512024.
10.3390/ijms241512024
- Patrícia C. Pires; Mariana Fernandes; Francisca Nina; Francisco Gama; Maria F. Gomes; Lina E. Rodrigues; Sara Meirinho; et
al. "Innovative Aqueous Nanoemulsion Prepared by Phase Inversion Emulsification with Exceptional Homogeneity". Pharmaceutics
(2023): https://doi.org/10.3390/pharmaceutics15071878.
10.3390/pharmaceutics15071878
- Meirinho, Sara; Rodrigues, Márcio; SANTOS, ADRIANA O.; Falcão, Amílcar; Alves, Gilberto. Autor correspondente: Alves, Gilberto.
"Nose-to-brain delivery of perampanel formulated in a self-microemulsifying drug delivery system improves anticonvulsant and
anxiolytic activity in mice". International Journal of Pharmaceutics 642 (2023): 123145. http://dx.doi.org/10.1016/j.ijpharm.2023.123145.
10.1016/j.ijpharm.2023.123145
- Sara Meirinho; Márcio Rodrigues; Adriana O. Santos; Amílcar Falcão; Gilberto Alves. "Intranasal Microemulsion as an Innovative
and Promising Alternative to the Oral Route in Improving Stiripentol Brain Targeting". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15061641.
10.3390/pharmaceutics15061641
- Ana C. Gonçalves; Ana R. Nunes; Sara Meirinho; Miguel Ayuso-Calles; Rocío Roca-Couso; Raúl Rivas; Amílcar Falcão; et al. "Exploring
the Antioxidant, Antidiabetic, and Antimicrobial Capacity of Phenolics from Blueberries and Sweet Cherries". Applied Sciences
(2023): https://doi.org/10.3390/app13106348.
10.3390/app13106348
- Ana R. Nunes; Elisabete C. Costa; Gilberto Alves; Luís R. Silva. "Nanoformulations for the Delivery of Dietary Anthocyanins
for the Prevention and Treatment of Diabetes Mellitus and Its Complications". Pharmaceuticals (2023): https://doi.org/10.3390/ph16050736.
10.3390/ph16050736
- Vanessa Brito; Mariana Marques; Marta Esteves; Catarina Serra-Almeida; Gilberto Alves; Paulo Almeida; Liliana Bernardino;
Samuel Silvestre. "Synthesis, In Vitro Biological Evaluation of Antiproliferative and Neuroprotective Effects and In Silico
Studies of Novel 16E-Arylidene-5a,6a-epoxyepiandrosterone Derivatives". Biomedicines (2023): https://doi.org/10.3390/biomedicines11030812.
10.3390/biomedicines11030812
- Mariana Matias; Adriana O. Santos; Samuel Silvestre; Gilberto Alves. "Fighting Epilepsy with Nanomedicines—Is This the Right
Weapon?". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15020306.
10.3390/pharmaceutics15020306
- Ana C. Gonçalves; Fernando Sánchez-Juanes; Sara Meirinho; Luís R. Silva; Gilberto Alves; José David Flores-Félix. "Insight
into the Taxonomic and Functional Diversity of Bacterial Communities Inhabiting Blueberries in Portugal". Microorganisms
(2022): https://doi.org/10.3390/microorganisms10112193.
10.3390/microorganisms10112193
- Ana R. Nunes; José D. Flores-Félix; Ana C. Gonçalves; Amílcar Falcão; Gilberto Alves; Luís R. Silva. "Anti-Inflammatory and
Antimicrobial Activities of Portuguese Prunus avium L. (Sweet Cherry) By-Products Extracts". Nutrients (2022): https://doi.org/10.3390/nu14214576.
10.3390/nu14214576
- Ana C. Gonçalves; Amílcar Falcão; Gilberto Alves; João A. Lopes; Luís R. Silva. "Employ of Anthocyanins in Nanocarriers for
Nano Delivery: In Vitro and In Vivo Experimental Approaches for Chronic Diseases". Pharmaceutics (2022): https://doi.org/10.3390/pharmaceutics14112272.
10.3390/pharmaceutics14112272
- Radhia Aitfella Lahlou; Nsevolo Samba; Pedro Soeiro; Gilberto Alves; Ana Carolina Gonçalves; Luís R. Silva; Samuel Silvestre;
Jesus Rodilla; Maria Isabel Ismael. "Thymus hirtus Willd. ssp. algeriensis Boiss. and Reut: A Comprehensive Review on Phytochemistry,
Bioactivities, and Health-Enhancing Effects". Foods (2022): https://doi.org/10.3390/foods11203195.
10.3390/foods11203195
- Vanessa Brito; Adriana Oliveira Santos; Gilberto Alves; Paulo Almeida; Samuel Silvestre. "Novel 4-Azapregnene Derivatives
as Potential Anticancer Agents: Synthesis, Antiproliferative Activity and Molecular Docking Studies". Molecules (2022):
https://doi.org/10.3390/molecules27186126.
10.3390/molecules27186126
- Sara Meirinho; Márcio Rodrigues; Adriana O. Santos; Amílcar Falcão; Gilberto Alves. "Self-Emulsifying Drug Delivery Systems:
An Alternative Approach to Improve Brain Bioavailability of Poorly Water-Soluble Drugs through Intranasal Administration".
Pharmaceutics (2022): https://doi.org/10.3390/pharmaceutics14071487.
10.3390/pharmaceutics14071487
- Ana C. Gonçalves; Ana R. Nunes; José D. Flores-Félix; Gilberto Alves; Luís R. Silva. "Cherries and Blueberries-Based Beverages:
Functional Foods with Antidiabetic and Immune Booster Properties". Molecules 27 10 (2022): 3294-3294. https://doi.org/10.3390/molecules27103294.
10.3390/molecules27103294
- Ana R. Nunes; Fernando Sánchez-Juanes; Ana C. Gonçalves; Gilberto Alves; Luís R. Silva; José David Flores-Félix. "Evaluation
of Raw Cheese as a Novel Source of Biofertilizer with a High Level of Biosecurity for Blueberry". Agronomy (2022):
https://doi.org/10.3390/agronomy12051150.
10.3390/agronomy12051150
- Ana C. Gonçalves; Dário Gaspar; José David Flores-Félix; Amílcar Falcão; Gilberto Alves; Luís R. Silva. "Effects of Functional
Phenolics Dietary Supplementation on Athletes’ Performance and Recovery: A Review". International Journal of Molecular
Sciences (2022): https://doi.org/10.3390/ijms23094652.
10.3390/ijms23094652
- Gonçalves, Ana C.; Gaspar, Dário; Amílcar Falcão; Alves, Gilberto; Luís R. Silva. "Effects of functional phenolics dietary
supplementation on athletes' performance and recovery: a detailed review". International Journal of Molecular Sciences
23 4652 (2022): https://doi.org/10.3390/ijms23094652.
Publicado • https://doi.org/10.3390/ijms23094652
- Catarina Canário; Mariana Matias; Vanessa Brito; Patrícia Pires; Adriana O. Santos; Amílcar Falcão; Samuel Silvestre; Gilberto
Alves. "C-Ring Oxidized Estrone Acetate Derivatives: Assessment of Antiproliferative Activities and Docking Studies". Applied
Sciences 12 7 (2022): 3579-3579. https://doi.org/10.3390/app12073579.
10.3390/app12073579
- Cristina Monteiro; Samuel Silvestre; Ana Paula Duarte; Gilberto Alves. "Safety of Non-Steroidal Anti-Inflammatory Drugs in
the Elderly: An Analysis of Published Literature and Reports Sent to the Portuguese Pharmacovigilance System". International
Journal of Environmental Research and Public Health 19 6 (2022): 3541-3541. https://doi.org/10.3390/ijerph19063541.
10.3390/ijerph19063541
- Ana Gonçalves; José Flores-Félix; Paula Coutinho; Gilberto Alves; Luís Silva. "Zimbro (Juniperus communis L.) as a Promising
Source of Bioactive Compounds and Biomedical Activities: A Review on Recent Trends". International Journal of Molecular
Sciences 23 6 (2022): 3197-3197. https://doi.org/10.3390/ijms23063197.
10.3390/ijms23063197
- Patrícia C. Pires; Márcio Rodrigues; Gilberto Alves; Adriana O. Santos. "Strategies to Improve Drug Strength in Nasal Preparations
for Brain Delivery of Low Aqueous Solubility Drugs". Pharmaceutics (2022):
10.3390/pharmaceutics14030588
- Ana R. Nunes; Ana C. Gonçalves; Edgar Pinto; Filipa Amaro; José D. Flores-Félix; Agostinho Almeida; Paula Guedes de Pinho;
et al. "Mineral Content and Volatile Profiling of Prunus avium L. (Sweet Cherry) By-Products from Fundão Region (Portugal)".
Foods (2022): https://doi.org/10.3390/foods11050751.
10.3390/foods11050751
- Canário C; Matias M; Brito V; Cruz-Vicente P; Soeiro P; Santos AO; Falcão A; Silvestre S; Alves G. "10ß-Hydroxyestra-1,4-diene-3,17-dione
as potential antiproliferative agent: in vitro biological evaluation and in silico studies.". Natural product research
(2022): http://europepmc.org/abstract/med/35167416.
10.1080/14786419.2022.2039136
- Meirinho, S.; Rodrigues, M.; Fortuna, A.; Falcão, A.; Alves, G.. "Study of the metabolic stability profiles of perampanel,
rufinamide and stiripentol and prediction of drug interactions using HepaRG cells as an in vitro human model". Toxicology
in Vitro 82 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85130269775&partnerID=MN8TOARS.
10.1016/j.tiv.2022.105389
- Ana C. Gonçalves; Márcio Rodrigues; José David Flores-Félix; Gonçalo Campos; Ana R. Nunes; Alessandra Braga Ribeiro; Luís
R. Silva; Gilberto Alves. "Sweet cherry phenolics revealed to be promising agents in inhibiting P-glycoprotein activity and
increasing cellular viability under oxidative stress conditions: in vitro and in silico study". Journal of Food Science
(2021): https://doi.org/10.1111/1750-3841.16001.
10.1111/1750-3841.16001
- Silva S; Bicker J; Fonseca C; Ferreira NR; Vitorino C; Alves G; Falcão A; Fortuna A. "Encapsulated Escitalopram and Paroxetine
Intranasal Co-Administration: In Vitro/In Vivo Evaluation.". Frontiers in pharmacology (2021): http://europepmc.org/abstract/med/34925013.
10.3389/fphar.2021.751321
- Ana C. Gonçalves; Radhia Aitfella Lahlou; Gilberto Alves; Cristina Garcia-Viguera; Diego A. Moreno; Luís R. Silva. "Potential
Activity of Abrantes Pollen Extract: Biochemical and Cellular Model Studies". Foods (2021): https://doi.org/10.3390/foods10112804.
10.3390/foods10112804
- Ana C. Gonçalves; José D. Flores-Félix; Ana R. Costa; Amílcar Falcão; Gilberto Alves; Luís R. Silva. "Hepatoprotective Effects
of Sweet Cherry Extracts (cv. Saco)". Foods (2021): https://doi.org/10.3390/foods10112623.
10.3390/foods10112623
- Candeias C; Gama J; Rodrigues M; Falcão A; Alves G. "Potentially Inappropriate Medications and Potential Prescribing Omissions
in Elderly Patients Receiving Post-Acute and Long-Term Care: Application of Screening Tool of Older People's Prescriptions/Screening
Tool to Alert to Right Treatment Criteria.". Frontiers in pharmacology (2021): http://europepmc.org/abstract/med/34737705.
10.3389/fphar.2021.747523
- Ana R. Nunes; Ana C. Gonçalves; Amílcar Falcão; Gilberto Alves; Luís R. Silva. "Prunus avium L. (Sweet Cherry) By-Products:
A Source of Phenolic Compounds with Antioxidant and Anti-Hyperglycemic Properties—A Review". Applied Sciences 11 18
(2021): 8516-8516. https://doi.org/10.3390/app11188516.
10.3390/app11188516
- José David Flores-Félix; Ana C. Gonçalves; Gilberto Alves; Luís R. Silva. "Consumption of Phenolic-Rich Food and Dietary Supplements
as a Key Tool in SARS-CoV-19 Infection". Foods (2021): https://doi.org/10.3390/foods10092084.
10.3390/foods10092084
- Catharine Falch; Gilberto Alves. "Pharmacists’ Role in Older Adults’ Medication Regimen Complexity: A Systematic Review".
International Journal of Environmental Research and Public Health (2021): https://doi.org/10.3390/ijerph18168824.
10.3390/ijerph18168824
- Ana C. Gonçalves; Ana R. Nunes; Amílcar Falcão; Gilberto Alves; Luís R. Silva. "Dietary Effects of Anthocyanins in Human Health:
A Comprehensive Review". Pharmaceuticals 14 7 (2021): 690-690. https://doi.org/10.3390/ph14070690.
10.3390/ph14070690
- Gonçalves AC; Campos G; Pinto E; Oliveira AS; Almeida A; de Pinho PG; Alves G; Silva LR. "Essential and non-essential elements,
and volatile organic compounds for the discrimination of twenty-three sweet cherry cultivars from Fundão, Portugal.". Food
chemistry (2021): http://europepmc.org/abstract/med/34352697.
10.1016/j.foodchem.2021.130503
- Pires PC; Fazendeiro AC; Rodrigues M; Alves G; Santos AO. "Nose-to-brain delivery of phenytoin and its hydrophilic prodrug
fosphenytoin combined in a microemulsion - formulation development and in vivo pharmacokinetics.". European journal of
pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences (2021): http://europepmc.org/abstract/med/34174414.
10.1016/j.ejps.2021.105918
- Ana R. Nunes; Ana C. Gonçalves; Gilberto Alves; Amílcar Falcão; Cristina Garcia-Viguera; Diego A. Moreno; Luís R. Silva. "Valorisation
of Prunus avium L. By-Products: Phenolic Composition and Effect on Caco-2 Cells Viability". Foods 10 6 (2021): 1185-1185.
https://doi.org/10.3390/foods10061185.
10.3390/foods10061185
- Catarina Canário; Mariana Matias; Vanessa Brito; Adriana O. Santos; Amílcar Falcão; Samuel Silvestre; Gilberto Alves. "New
Estrone Oxime Derivatives: Synthesis, Cytotoxic Evaluation and Docking Studies". Molecules (2021): https://doi.org/10.3390/molecules26092687.
10.3390/molecules26092687
- José David Flores Félix; Fernando Sanchez-Juanes; Luis R. Silva; Gilberto Alves. "Metagenomic and Culturomic Approaches for
Blueberry Biofertilizer Design". Biology and Life Sciences Forum (2021): https://doi.org/10.3390/IECAG2021-09668.
10.3390/IECAG2021-09668
- Monteiro C; Silvestre S; Duarte AP; Alves G. "Assessment of suspected adverse drug reactions in elderly patients with diabetes
mellitus based on a Portuguese spontaneous reporting database: analysis of reporting from 2008 to 2018.". Expert opinion
on drug safety (2021): http://europepmc.org/abstract/med/33962523.
10.1080/14740338.2021.1928072
- Vanessa Brito; Gilberto Alves; Paulo Almeida; Samuel Silvestre. "Highlights on Steroidal Arylidene Derivatives as a Source
of Pharmacologically Active Compounds: A Review". Molecules 26 7 (2021): 2032-2032. https://doi.org/10.3390/molecules26072032.
10.3390/molecules26072032
- Ana C. Gonçalves; Ana R. Nunes; Gilberto Alves; Luís R. Silva. "Serotonin and Melatonin: Plant Sources, Analytical Methods,
and Human Health Benefits". Revista Brasileira de Farmacognosia (2021): https://doi.org/10.1007/s43450-021-00141-w.
10.1007/s43450-021-00141-w
- Ana C. Gonçalves; Gonçalo Campos; Gilberto Alves; Cristina Garcia-Viguera; Diego A. Moreno; Luís R. Silva. "Physical and phytochemical
composition of 23 Portuguese sweet cherries as conditioned by variety (or genotype)". Food Chemistry 335 (2021): 127637-127637.
https://doi.org/10.1016/j.foodchem.2020.127637.
10.1016/j.foodchem.2020.127637
- Joana Gonçalves; Soraia Silva; Filipa Gouveia; Joana Bicker; Amílcar Falcão; Gilberto Alves; Ana Fortuna. "A combo-strategy
to improve brain delivery of antiepileptic drugs: Focus on BCRP and intranasal administration". International Journal of
Pharmaceutics 593 (2021): 120161-120161. https://doi.org/10.1016/j.ijpharm.2020.120161.
10.1016/j.ijpharm.2020.120161
- Gonçalves, J.; Alves, G.; Fonseca, C.; Carona, A.; Bicker, J.; Falcão, A.; Fortuna, A.. "Is intranasal administration an opportunity
for direct brain delivery of lacosamide?". European Journal of Pharmaceutical Sciences 157 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85095858521&partnerID=MN8TOARS.
10.1016/j.ejps.2020.105632
- Monteiro, C.; Duarte, A.P.; Alves, G.. "Adverse drug reactions in elderly: a five-year review of spontaneous reports to the
Portuguese pharmacovigilance system". Expert Opinion on Drug Safety 20 1 (2021): 109-118. http://www.scopus.com/inward/record.url?eid=2-s2.0-85097862523&partnerID=MN8TOARS.
10.1080/14740338.2020.1849137
- Aitfella Lahlou, R.; Bounechada, M.; Mohammedi, A.; Silva, L.R.; Alves, G.. "Dietary use of Rosmarinus officinalis and Thymus
vulgaris as anticoccidial alternatives in poultry". Animal Feed Science and Technology 273 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85100383542&partnerID=MN8TOARS.
10.1016/j.anifeedsci.2021.114826
- Pires, P.C.; Santos, L.T.; Rodrigues, M.; Alves, G.; Santos, A.O.. "Intranasal fosphenytoin: The promise of phosphate esters
in nose-to-brain delivery of poorly soluble drugs". International Journal of Pharmaceutics 592 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85095847981&partnerID=MN8TOARS.
10.1016/j.ijpharm.2020.120040
- Eusébio, D.; Neves, A.R.; Costa, D.; Biswas, S.; Alves, G.; Cui, Z.; Sousa, Â.. "Methods to improve the immunogenicity of
plasmid DNA vaccines". Drug Discovery Today 26 11 (2021): 2575-2592. http://www.scopus.com/inward/record.url?eid=2-s2.0-85109464115&partnerID=MN8TOARS.
10.1016/j.drudis.2021.06.008
- Ana Carolina Gonçalves; Catarina Bento; Ana R. Nunes; Manuel Simões; Gilberto Alves; Luís R. Silva. "Multitarget protection
of Pterospartum tridentatum phenolic-rich extracts against a wide range of free radical species, antidiabetic activity and
effects on human colon carcinoma (Caco-2) cells". Journal of Food Science (2020): https://doi.org/10.1111/1750-3841.15511.
10.1111/1750-3841.15511
- Sara Meirinho; Gonçalo Campos; Márcio Rodrigues; Ana Fortuna; Amílcar Falcão; Gilberto Alves. "Salting-out assisted liquid–liquid
extraction method optimized by design of experiments for the simultaneous high-performance liquid chromatography analysis
of perampanel and stiripentol in mouse matrices". Journal of Separation Science (2020): https://doi.org/10.1002/jssc.202000656.
10.1002/jssc.202000656
- Márcio Rodrigues; Ana Clara Lopes; Filipa Vaz; Melanie Filipe; Gilberto Alves; Maximiano P. Ribeiro; Paula Coutinho; André
R. T. S. Araujo. "Thymus mastichina: Composition and Biological Properties with a Focus on Antimicrobial Activity". Pharmaceuticals
(2020): https://doi.org/10.3390/ph13120479.
10.3390/ph13120479
- Meirinho S; Rodrigues M; Fortuna A; Falcão A; Alves G. "Liquid chromatographic methods for determination of the new antiepileptic
drugs stiripentol, retigabine, rufinamide and perampanel: A comprehensive and critical review.". Journal of pharmaceutical
analysis (2020): http://europepmc.org/abstract/med/34513117.
10.1016/j.jpha.2020.11.005
- Sarah Pousinho; Manuel Morgado; Ana I. Plácido; Fátima Roque; Amílcar Falcão; Gilberto Alves. "Clinical pharmacists´ interventions
in the management of type 2 diabetes mellitus: a systematic review". Pharmacy Practice (2020): https://doi.org/10.18549/PharmPract.2020.3.2000.
10.18549/PharmPract.2020.3.2000
- Canário, Catarina; Matias, Mariana; de Brito, Vanessa; Santos, Adriana O.; Falcão, Amílcar; Silvestre, Samuel; Alves, Gilberto.
"D9,11-Estrone derivatives as potential antiproliferative agents: synthesis, in vitro biological evaluation and docking studies".
Comptes Rendus. Chimie 23 2 (2020): 201-217. http://dx.doi.org/10.5802/crchim.17.
10.5802/crchim.17
- Canário, Catarina; Matias, Mariana; Brito, Vanessa; SANTOS, ADRIANA O.; Amílcar Falcão; Silvestre, Samuel; Alves, Gilberto.
"Delta9,11 -Estrone derivatives as potential antiproliferative agents: synthesis, in vitro biological evaluation and docking
studies". Comptes Rendus Chimie 23 2 (2020): 201-2017. https://comptes-rendus.academie-sciences.fr/chimie/item/CRCHIM_2020__23_2_201_0/.
Publicado • https://doi.org/10.5802/crchim.17
- Cristina Monteiro; Catarina Canário; Manuel Ângelo Ribeiro; Ana Paula Duarte; Gilberto Alves. "
Medication Evaluation in
Portuguese Elderly Patients According to Beers, STOPP/START Criteria and EU(7)-PIM List – An Exploratory Study ". Patient
Preference and Adherence (2020): https://doi.org/10.2147/PPA.S247013.
10.2147/PPA.S247013
- Gonçalves, Ana C.; Nunes, Ana R.; Simões, M.; Silva, Luís R.; Alves, Gilberto. "Pterospartum tridentatum extract protect human
erythrocyte membranes against oxidative damage and possess antidiabetic potential". Journal of Food Science (2020):
Publicado
- Luís R. Silva; Ana C. Gonçalves; Ana R. Nunes; Gilberto Alves. "Authentication of honeys from Caramulo region (Portugal):
Pollen spectrum, physicochemical characteristics, mineral content, and phenolic profile". Journal of Food Science (2020):
https://doi.org/10.1111/1750-3841.15023.
10.1111/1750-3841.15023
- Joana Bicker; Gilberto Alves; Amílcar Falcão; Ana Fortuna. "Timing in drug absorption and disposition: the past, present and
future of chronopharmacokinetics". British Journal of Pharmacology (2020): https://doi.org/10.1111/bph.15017.
10.1111/bph.15017
- Joana Bicker; Ana Fortuna; Gilberto Alves; Amílcar Falcão. "Nose-to-brain Delivery of Natural Compounds for the Treatment
of Central Nervous System Disorders". Current Pharmaceutical Design (2020): https://doi.org/10.2174/1381612826666200115101544.
10.2174/1381612826666200115101544
- Patrícia C. Pires; Diana Peixoto; Isaura Teixeira; Márcio Rodrigues; Gilberto Alves; Adriana O. Santos. "Nanoemulsions and
thermosensitive nanoemulgels of phenytoin and fosphenytoin for intranasal administration: Formulation development and in vitro
characterization". European Journal of Pharmaceutical Sciences 141 (2020): 105099-105099. https://doi.org/10.1016/j.ejps.2019.105099.
10.1016/j.ejps.2019.105099
- Gouveia, F.; Bicker, J.; Santos, J.; Rocha, M.; Alves, G.; Falcão, A.; Fortuna, A.. "Development, validation and application
of a new HPLC-DAD method for simultaneous quantification of apixaban, dabigatran, edoxaban and rivaroxaban in human plasma".
Journal of Pharmaceutical and Biomedical Analysis 181 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85078513077&partnerID=MN8TOARS.
10.1016/j.jpba.2020.113109
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Parkinson’s disease rat model using an upgraded paraquat exposure paradigm". European Journal of Neuroscience (2020):
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10.1111/ejn.14683
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10.2174/1573407214666181026111431
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Delivery of Zonisamide After Intranasal Administration". Pharmaceutical Research 37 4 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85082452374&partnerID=MN8TOARS.
10.1007/s11095-020-02786-z
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in Phenolic Compounds". Food Reviews International (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85097523069&partnerID=MN8TOARS.
10.1080/87559129.2020.1854781
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treatments". Pharmacological Research 162 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85095823211&partnerID=MN8TOARS.
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of fluoxetine in a real-world setting: A PK/PD analysis of the influence of (non-)genetic factors.". Experimental and Clinical
Psychopharmacology (2019): https://doi.org/10.1037/pha0000334.
10.1037/pha0000334
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with depression treated with antidepressant drugs focused on (non-)genetic factors, pharmacokinetics, and clinical outcomes:
GnG-PK/PD-AD study.". Experimental and Clinical Psychopharmacology (2019): https://doi.org/10.1037/pha0000294.
10.1037/pha0000294
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10.1080/01480545.2019.1601736
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10.1016/j.ijpharm.2019.04.047
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of lamotrigine given as a single-dose in Wistar rats". Food and Chemical Toxicology 128 (2019): 61-67. http://www.scopus.com/inward/record.url?eid=2-s2.0-85063732494&partnerID=MN8TOARS.
10.1016/j.fct.2019.03.051
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multidrug resistance: Focus on antiepileptic drugs". Food and Chemical Toxicology 111 (2018): 84-93. http://www.scopus.com/inward/record.url?eid=2-s2.0-85033366631&partnerID=MN8TOARS.
10.1016/j.fct.2017.11.004
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colistin quantification and its plasma monitoring in hospitalized patients". Analytical Methods 10 3 (2018): 389-396.
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of antiepileptic drugs for pharmacoresistant epilepsy". Epilepsy Research 146 (2018): 63-86. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050938227&partnerID=MN8TOARS.
10.1016/j.eplepsyres.2018.07.008
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array detection technique to simultaneously quantify lacosamide, levetiracetam and zonisamide in human plasma". Bioanalysis
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10.4155/bio-2017-0199
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on lamotrigine pharmacokinetics: Insights from in vivo studies in rats". Food and Chemical Toxicology 121 (2018): 166-172.
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10.1016/j.fct.2018.08.069
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of new drug candidates: Focus on in vivo pharmaco-toxicological assays based on the rotarod performance test". Journal
of Pharmacy and Pharmaceutical Sciences 21 1 (2018): 110-118. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044151077&partnerID=MN8TOARS.
10.18433/jpps29656
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simultaneous determination of five neuroactive amino acids in different regions of rat brain". Journal of Pharmacological
and Toxicological Methods 91 (2018): 72-79. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041549306&partnerID=MN8TOARS.
10.1016/j.vascn.2018.02.002
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13 2 (2018): 74-83. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048878403&partnerID=MN8TOARS.
10.2174/1574886313666180213090943
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ß-hydroxylase inhibitors with human P-glycoprotein and Breast Cancer Resistance Protein". European Journal of Pharmaceutical
Sciences 117 (2018): 35-40. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041551169&partnerID=MN8TOARS.
10.1016/j.ejps.2018.02.006
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10.2174/1389200219666180629121033
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"Effects of Paullinia cupana extract on lamotrigine pharmacokinetics in rats: A herb-drug interaction on the gastrointestinal
tract with potential clinical impact". Food and Chemical Toxicology 115 (2018): 170-177. http://www.scopus.com/inward/record.url?eid=2-s2.0-85043505393&partnerID=MN8TOARS.
10.1016/j.fct.2018.03.011
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extract and lamotrigine: data from pharmacokinetic studies in the rat". Drug and Chemical Toxicology (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85055292875&partnerID=MN8TOARS.
10.1080/01480545.2018.1518454
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Cherry Fruits". Nutrients 10 11 (2018): 1688-1688. http://hdl.handle.net/10314/4430.
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human health". International Journal of Environmental Research and Public Health (2018):
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using a thermoreversible in situ gel". European Journal of Pharmaceutical Sciences 97 (2017): 30-37. http://www.scopus.com/inward/record.url?eid=2-s2.0-84994832134&partnerID=MN8TOARS.
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COMT inhibitor, after single and multiple oral administration: A comparative study in the rat". Toxicology and Applied
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A New Tool Based on Microextraction by Packed Sorbent Coupled to Liquid Chromatography". Journal of analytical toxicology
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10.1093/jat/bkx043
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dihydropyrimidin(thi)one derivatives using a combo of in vitro and in silico assays". European Journal of Pharmaceutical
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10.1016/j.ejps.2017.08.023
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Pharmacokinetic Study". Pharmaceutical Research 34 11 (2017): 2260-2269. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026916021&partnerID=MN8TOARS.
10.1007/s11095-017-2232-1
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potential anticonvulsant drug candidates". European Journal of Pharmaceutical Sciences 102 (2017): 264-274. http://www.scopus.com/inward/record.url?eid=2-s2.0-85015869893&partnerID=MN8TOARS.
10.1016/j.ejps.2017.03.014
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to investigate the pharmacokinetics and pharmacodynamics of opicapone, a novel COMT inhibitor, in rat". Neuropharmacology
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10.1016/j.neuropharm.2017.07.019
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of lamotrigine in human plasma and saliva using microextraction by packed sorbent and high performance liquid chromatography–diode
array detection: An innovative bioanalytical tool for therapeutic drug monitoring". Microchemical Journal 130 (2017):
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a novel catechol-O-methyltransferase inhibitor, in the Wistar rat". Parkinsonism & Related Disorders 22 (2016): e184-e184.
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23 12 (2016): 1511-1526. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988527743&partnerID=MN8TOARS.
10.1016/j.phymed.2016.09.001
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A systematic review of randomized controlled trials". Journal of Managed Care and Specialty Pharmacy 22 5 (2016): 493-515.
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Influence on the bioavailability of intranasally administered drugs". Current Drug Metabolism 17 7 (2016): 628-647.
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activation and dopaminergic neuronal toxicity via H1 receptor activation". Journal of Neuroinflammation 13 1 (2016):
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enzymes be used in the rat for drug interaction studies?". Journal of Pharmacy and Pharmaceutical Sciences 19 4 (2016):
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of potential antitumoral 3,4-dihydropyrimidin-2-(1H)-thiones". Arabian Journal of Chemistry (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85008352523&partnerID=MN8TOARS.
10.1016/j.arabjc.2016.12.007
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chemistry, pharmacology and toxicology". Phytochemistry Reviews 15 1 (2016): 51-85. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957433866&partnerID=MN8TOARS.
10.1007/s11101-014-9384-y
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E.. "Effects of Hypericum perforatum extract and its main bioactive compounds on the cytotoxicity and expression of CYP1A2
and CYP2D6 in hepatic cells". Life Sciences 144 (2016): 30-36. http://www.scopus.com/inward/record.url?eid=2-s2.0-84948692116&partnerID=MN8TOARS.
10.1016/j.lfs.2015.11.004
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for screening the blood-brain barrier permeability of drug candidates". International Journal of Pharmaceutics 501
1-2 (2016): 102-111. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957593450&partnerID=MN8TOARS.
10.1016/j.ijpharm.2016.01.074
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the determination of opicapone and BIA 9-1079 in rat matrices". Biomedical Chromatography 30 3 (2016): 312-322. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956591120&partnerID=MN8TOARS.
10.1002/bmc.3550
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perforatum hydroalcoholic extract, hypericin, and hyperforin on cytotoxicity and CYP3A4 mRNA expression in hepatic cell lines:
a comparative study". Medicinal Chemistry Research 25 12 (2016): 2999-3010. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988613657&partnerID=MN8TOARS.
10.1007/s00044-016-1702-z
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H)-ones: synthesis, in vitro biological evaluation and QSAR studies". RSC Advances 6 88 (2016): 84943-84958. http://www.scopus.com/inward/record.url?eid=2-s2.0-84987657546&partnerID=MN8TOARS.
10.1039/c6ra14596e
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Method for the Quantification of Carbamazepine, Oxcarbazepine and their Active Metabolites in HepaRG Cell Culture Samples".
A new, sensitive and fast high-performance liquid chromatography–diode-array detection assay is herein reported, for the
first time, to simultaneously quantify carbamazepine (CBZ), oxcarbazepine (OXC), and the active metabolites carbamazepine-10,11-epoxide
(CBZ-E) and licarbazepine (LIC) in HepaRG cell culture medium samples. Chromatographic separation of analytes (CBZ, CBZE,
OXC, LIC) and interna 79 9-10 (2016): 581-590. http://hdl.handle.net/10314/3102.
10.1007/s10337-016-3063-7
- Ferreira, A.; Pousinho, S.; Fortuna, A.; Falcão, A.; Alves, G.. "Flavonoid compounds as reversal agents of the P-glycoprotein-mediated
multidrug resistance: biology, chemistry and pharmacology". Phytochemistry Reviews 14 2 (2015): 233-272. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939874562&partnerID=MN8TOARS.
10.1007/s11101-014-9358-0
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of safety and toxicity profiles". Current Drug Safety 9 2 (2014): 89-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904717224&partnerID=MN8TOARS.
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of CNS drug delivery systems: A review". European Journal of Pharmaceutics and Biopharmaceutics 87 3 (2014): 409-432.
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10.1016/j.ejpb.2014.03.012
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and biomacromolecules". European Journal of Pharmaceutics and Biopharmaceutics (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84897968392&partnerID=MN8TOARS.
10.1016/j.ejpb.2014.03.004
- Fortuna, A.; Alves, G.; Falcão, A.. "Chiral chromatographic resolution of antiepileptic drugs and their metabolites: A challenge
from the optimization to the application". Biomedical Chromatography 28 1 (2014): 27-58. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890227798&partnerID=MN8TOARS.
10.1002/bmc.3004
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chromatographic assay based on microextraction by packed sorbent for therapeutic drug monitoring of carbamazepine, lamotrigine,
oxcarbazepine, phenobarbital, phenytoin and the active metabolites carbamazepine-10,11-epoxide and licarbazepine". Journal
of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 971 (2014): 20-29. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907542842&partnerID=MN8TOARS.
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of venlafaxine and O-desmethylvenlafaxine in human plasma". Bioanalysis 6 22 (2014): 3025-3038. http://www.scopus.com/inward/record.url?eid=2-s2.0-84918518098&partnerID=MN8TOARS.
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administration of carbamazepine to mice: A direct delivery pathway for brain targeting". European Journal of Pharmaceutical
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of phenobarbital, primidone, phenytoin, carbamazepine, carbamazepine-10,11-epoxide, 10,11-trans-dihydroxy-10,11-dihydrocarbamazepine,
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amiodarone and its major metabolite in rat plasma and tissues: A useful tool for pharmacokinetic studies". Journal of Chromatographic
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of amiodarone and desethylamiodarone in human plasma using microextraction by packed sorbent (MEPS) as sample preparation
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10.1016/j.jchromb.2012.11.028
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10.1016/j.aca.2012.12.030
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10.1016/j.fct.2012.11.012
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the effect of Citrus aurantium fruit extract on the pharmacokinetics of amiodarone in rats". Food and Chemical Toxicology
60 (2013): 153-159. http://hdl.handle.net/10316/27406.
10.1016/j.fct.2013.07.041
- Fortuna, A.; Alves, G.; Falcão, A.; Soares-Da-Silva, P.. "Evaluation of the permeability and P-glycoprotein efflux of carbamazepine
and several derivatives across mouse small intestine by the Ussing chamber technique". Epilepsia 53 3 (2012): 529-538.
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10.1111/j.1528-1167.2012.03409.x
- Fortuna, A.; Alves, G.; Almeida, A.; Lopes, B.; Falcão, A.; Soares-da-Silva, P.. "A chiral liquid chromatography method for
the simultaneous determination of oxcarbazepine, eslicarbazepine, R-licarbazepine and other new chemical derivatives BIA 2-024,
BIA 2-059 and BIA 2-265, in mouse plasma and brain". Biomedical Chromatography 26 3 (2012): 384-392. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856569184&partnerID=MN8TOARS.
10.1002/bmc.1670
- Serralheiro, A.; Alves, G.; Falcão, A.. "Bioanalysis of small-molecule drugs in nasal and paranasal tissues and secretions:
Current status and perspectives". Central European Journal of Chemistry 10 3 (2012): 686-702. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867098752&partnerID=MN8TOARS.
10.2478/s11532-012-0021-6
- Sousa, J.; Alves, G.; Fortuna, A.; Falcão, A.. "Analytical methods for determination of new fluoroquinolones in biological
matrices and pharmaceutical formulations by liquid chromatography: A review". Analytical and Bioanalytical Chemistry
403 1 (2012): 93-129. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858745738&partnerID=MN8TOARS.
10.1007/s00216-011-5706-8
- Fortuna, A.; Alves, G.; Soares-da-silva, P.; Falcão, A.. "Optimization of a parallel artificial membrane permeability assay
for the fast and simultaneous prediction of human intestinal absorption and plasma protein binding of drug candidates: Application
to dibenz[b,f]azepine-5-carboxamide derivatives". Journal of Pharmaceutical Sciences 101 2 (2012): 530-540. http://www.scopus.com/inward/record.url?eid=2-s2.0-84455169538&partnerID=MN8TOARS.
10.1002/jps.22796
- Gonçalves, D.; Alves, G.; Soares-da-Silva, P.; Falcão, A.. "Bioanalytical chromatographic methods for the determination of
catechol-O-methyltransferase inhibitors in rodents and human samples: A review". Analytica Chimica Acta 710 (2012):
17-32. http://www.scopus.com/inward/record.url?eid=2-s2.0-84155162415&partnerID=MN8TOARS.
10.1016/j.aca.2011.10.026
- Rodrigues, M.; Alves, G.; Lourenço, N.; Falcão, A.. "Herb-drug interaction of Paullinia cupana (Guarana) seed extract on the
pharmacokinetics of amiodarone in rats". Evidence-based Complementary and Alternative Medicine 2012 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84871368693&partnerID=MN8TOARS.
10.1155/2012/428560
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in biological matrices and pharmaceutical formulations by liquid chromatography: A review (Analytical and Bioanalytical Chemistry
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10.1002/jssc.201100099
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chromatography method for the simultaneous determination of norfloxacin, lomefloxacin and ciprofloxacin in human plasma".
Biomedical Chromatography 25 5 (2011): 535-541. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953682225&partnerID=MN8TOARS.
10.1002/bmc.1480
- Ana Fortuna; Gilberto Alves; Amílcar Falcão. "In vitro and In vivo Relevance of the P-glycoprotein Probe Substrates in Drug
Discovery and Development: Focus on Rhodamine 123, Digoxin and Talinolol". JBB 01 02 (2011): http://dx.doi.org/10.4172/jbb.s2-001.
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- Costa, I.M.; Serralheiro, A.I.; Rodrigues, M.; Alves, G.; Falcão, A.C.. "Usefulness of factor II and factor X as therapeutic
markers in patients under chronic warfarin therapy". Biomedicine and Pharmacotherapy 64 2 (2010): 130-132. http://www.scopus.com/inward/record.url?eid=2-s2.0-77349094508&partnerID=MN8TOARS.
10.1016/j.biopha.2009.09.020
- Fortuna, A.; Alves, G.; Falcão, A.; Soares-Da-Silva, P.. "Binding of licarbazepine enantiomers to mouse and human plasma proteins".
Biopharmaceutics and Drug Disposition 31 5-6 (2010): 362-366. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955704455&partnerID=MN8TOARS.
10.1002/bdd.716
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assay for therapeutic drug monitoring of eslicarbazepine acetate: No interference with carbamazepine and its metabolites".
Therapeutic Drug Monitoring 32 4 (2010): 512-516. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955173774&partnerID=MN8TOARS.
10.1097/FTD.0b013e3181e5c855
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simultaneous quantification of carbamazepine, oxcarbazepine, eslicarbazepine acetate and their main metabolites in human plasma".
Analytical and Bioanalytical Chemistry 397 4 (2010): 1605-1615. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953806616&partnerID=MN8TOARS.
10.1007/s00216-010-3673-0
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10.1002/bmc.858
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| Capítulo de livro |
- Brito, V.; Alves, G.; Almeida, P.; Silvestre, S.. "Oxidized steroids as 5a-reductase inhibitors with potential interest in
prostatic diseases: A review". 1-35. 2022.
- Nunes, A.R.; Gonçalves, A.C.; Falcão, A.; Alves, G.; Silva, L.R.. "Health benefits of phenolic compounds against diabetes:
Recent advances". 1-78. 2021.
- Serralheiro, Ana ; Bicker, Joana; Alves, Gilberto; Falcão, Amílcar; Fortuna, Ana. "Novel Routes to Accessing the Brain: Intranasal
Administration". In Nanoparticles for Brain Drug Delivery, editado por Vitorino, Carla; Jorge, Andreia; Pais, Alberto.
New York, Estados Unidos: Routledge - Taylor & Francis Group, 2021.
Publicado
- Bicker, Joana; Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "Understanding brain delivery". In Nanoparticles for Brain
Drug Delivery. 2020.
Publicado
- Alves, Gilberto. "Microextraction Techniques in LC-MS Bioanalysis". 98-116. John Wiley {\&, 2019.
10.1002/9781119274315.ch8
- Gonçalves, A.C.; Bento, C.; Jesus, F.; Alves, G.; Silva, L.R.. "Sweet Cherry Phenolic Compounds: Identification, Characterization,
and Health Benefits". 31-78. 2018.
10.1016/B978-0-444-64179-3.00002-5
- Alves, Gilberto. "Bioanalysis in drug discovery and development: Focus on pharmacokinetic studies". 191-210. 2011.
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| Edição de número de revista |
- Rodrigues, Márcio; Alves, Gilberto. "Pharmacokinetics of Orally Administered Drugs, 2nd edition". Pharmaceutics (2024):
https://www.mdpi.com/journal/pharmaceutics/special_issues/D9W2LR5FSO.
- Alves, Gilberto; Ali, Javed ; Rodrigues, Márcio. "Intranasal Delivery of Central Nervous System Active Drugs: Opportunities
and Challenges". Frontiers in Pharmacology (2022): https://www.frontiersin.org/research-topics/19861/intranasal-delivery-of-central-nervous-system-active-drugs-opportunities-and-challenges.
- Rodrigues, Márcio; Alves, Gilberto. "Pharmacokinetics of Orally Administered Drugs". Pharmaceutics (2022): https://www.mdpi.com/journal/pharmaceutics/special_issues/Orally_Administered_Drugs.
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| Entrada de enciclopédia |
- Gonçalves, Ana C.; Flores-Félix, José David; Nunes, Ana R.; Falcão, Amílcar; Alves, Gilberto; Silva, Luís R.. "Dietary Effects
of Anthocyanins in Human Health". In Encyclopedia on-line, 2023. https://encyclopedia.pub/entry/47729.
Publicado
- Martins, Mariana S.; Gonçalves, Ana C.; Alves, Gilberto; Silva, Luís R.. "Blackberries and Mulberries". In Encyclopedia
on-line MDPI. MDPI, 2023.
Publicado
- Gonçalves, Ana C.; Flores-Félix, José David; Coutinho, Paula; Alves, Gilberto; Silva, Luís R.. "Zimbro". In Encyclopedia
on-line MDPI. MDPI, 2022. https://encyclopedia.pub/22273.
Publicado
- Gonçalves, Ana C.; Gaspar, Dário; Flores-Félix, José David; Falcão, Amílcar; Alves, Gilberto; Silva, Luís R.. "Phenolic Compounds
and Its Linkage". In Encyclopedia on-line MDPI. MDPI, 2022. https://encyclopedia.pub/entry/22491.
Publicado
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| Livro |
- Magalhães, M.; Ferreira, D.; Martinho, A.; Rosado, T.; Figueirinha, D.; Pires, A.; Domingues, F.; et al. Are naphthodianthrones
the key molecules in the biological properties of hypericum perforatum?. 2017.
- Fortuna, A.; Alves, G.; Falcão, A.. Pharmacokinetics and bioanalysis to improve drug development. 2015.
10.1515/9783110468755-003
- Fortuna, A.; Alves, G.; Falcão, A.. The pharmacology of simvastatin: From the mechanism of action to new therapeutic applications.
2015.
- Matias, M.; Canário, C.; Silvestre, S.; Falcã, A.; Alves, G.. Cytochrome P450-mediated toxicity of therapeutic drugs.
2014.
- Serralheiro, A.; Alves, G.; Sousa, J.; Fortuna, A.; Falcão, A.. Nose as a route for drug delivery. 2013.
10.1007/978-3-642-37250-6_15
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| Poster em conferência |
- Silva, Luís R.; Gonçalves, Ana C.; Flores-Félix, José David; Falcão, Amílcar C.; Garcia-Viguera, Cristina; Moreno, Diego;
Alves, Gilberto. "Health-promoting properties of sweet cherry extracts". Trabalho apresentado em 4th International Conference
on Food Bioactives & Health, 2023.
- Flores-Félix, José David; Gonçalves, Ana C.; Meirinho, Sara; Garcia-Viguera, Cristina; Moreno, Diego A.; Alves, Gilberto;
Silva, Luís R.; et al. "Bacterial biofortification improves production and modifies organic chemical composition of blueberry".
Trabalho apresentado em 1st International Agrienvironment Symposium, 2023.
- N. Zione; Rodrigues, Márcio; Alves, G.; Matias, Mariana. "Quality control studies of antimalarial drugs in Africa: a systematic
review". Trabalho apresentado em XVIII International CICS-UBI Symposium, 2023.
- Meirinho, Sara; Rodrigues, Márcio; Ferreira, Catarina L.; SANTOS, ADRIANA O.; Amílcar Falcão; Alves, Gilberto. Autor correspondente:
Meirinho, Sara. "A Safe Self-microemulsifying Drug Delivery System as a Promising Strategy for Nose-to-Brain Delivery of
Perampanel". Trabalho apresentado em XVIII International CICS-UBI Symposium, 2023.
- Gonçalves, Ana C.; Falcão, Amílcar; Alves, Gilberto; Silva, Luís R.. "Sweet cherries possess anti-inflammatory effects and
exhibit anti-cancer effects against AGS cells". Trabalho apresentado em XVIII International CICS-UBI Symposium, 2023.
- Zione, N’suka; Rodrigues, Márcio; Alves, Gilberto; Matias, Mariana. "Quality control trials of antimalarial drugs in Africa:
A systematic review". Trabalho apresentado em XVIII International CICS-UBI Symposium, 2023.
- Fiadeiro, Mariana B.; Silva, Ana A.; Sousa, Ana C.; Silvestre, Samuel; ALMEIDA, MARCO; Alves, Gilberto; Meirinho, Sara; et
al. "Novel Ionic Liquid-based Nox1 inhibitor as a new approach to slow down Parkinson's disease progression". Trabalho apresentado
em FENS Regional Meeting 2023, Albufeira, Portugal, 2023.
- Gonçalves, Ana C.; Falcão, Amílcar; Alves, G.; Garcia-Viguera, Cristina; Moreno, Diego A.; Silva, Luís R.; Gilberto Alves;
et al. "Phenolics from sweet cherries exhibit antidiabetic effects and hepatoprotective effects". Trabalho apresentado em
1 st International Congress on Food, Nutrition & Public Health – Towards a sustainable future, 2022.
- Nunes, A. Raquel; Gonçalves, Ana C.; Flores-Félix, J. D.; Alves, G.; Falcão, A.; Garcia-Viguera, Cristina; Moreno, Diego A.;
Silva, Luís R.. "Potential of Prunus avium L. By-Products from Fundão region: Bioactive Composition and Anti-Inflammatory
Activity". Trabalho apresentado em 1 st International Congress on Food, Nutrition & Public Health – Towards a sustainable
future, 2022.
- Flores-Félix, José David; Gonçalves, Ana C.; Meirinho, Sara; Filipa Amaro; Cristina G. Viguera; Diego A. Moreno; Alves, Gilberto;
Paula Guedes de Pinho; Luís R. Silva. "Bacterial biofertilization improves production and modifies organic chemical composition
of blueberry". Trabalho apresentado em XVI Encontro de Química dos Alimentos: Bio-sustentabilidade e Bio-segurança alimentar,
Inovação e qualidade alimentar, 2022.
- Gonçalves, Ana C.; Ana Sofia Oliveira; Cristina Garcia-Viguera; Diego A. Moreno; Alves, Gilberto; Paula Guedes de Pinho; Luís
R. Silva. "Phytochemical profile and physicochemical characteristics of Fundão sweet cherries". Trabalho apresentado em XVI
Química dos Alimentos, 2022.
- Nunes, Ana R.; Gonçalves, Ana C.; Flores-Félix, José David; Amílcar Celta Falcão; Alves, Gilberto; Silva, Luís R.. "The anti-inflammatory
potential of Portuguese cherry by-products". Trabalho apresentado em XVII International CICS-UBI Symposium, 2022.
- Flores-Félix, José David; Gonçalves, Ana C.; Meirinho, Sara; Nunes, Ana R.; Silva, Luís R.; Alves, Gilberto. "Phenolic compounds
profile modification on blueberry fruit due to biofertilization treatments". Trabalho apresentado em XVII International
CICS-UBI Symposium, 2022.
- Matias, Mariana; Amílcar Falcão; Silvestre, Samuel; Alves, Gilberto. "Dihydropyrimidin(thi)ones as potential drug candidates
for epilepsy: a preclinical study". Trabalho apresentado em XVII International CICS-UBI Symposium, 2022.
- Nunes, Ana R.; Gonçalves, Ana C.; Flores-Félix, José David; Alves, Gilberto; Amílcar Celta Falcão; Cristina García-Viguera;
Moreno, Diego; Luís R. Silva. "Valorization of sweet cherry by-products: bioactive compounds with health benefits". Trabalho
apresentado em VI Jornadas de Educação e Investigação em Saúde, 2021.
- Flores-Félix, José David; Gonçalves, Ana C.; Ana R. Nunes; Alves, Gilberto; Luís R. Silva. "Improving the quality of the production
of blueberry throughout the inoculation of bacterial biofertilizers". Trabalho apresentado em IX COLAPLAMED 2021, 2021.
- Gonçalves, Ana C.; Ana R. Nunes; Flores-Félix, José David; Alves, Gilberto; Amílcar Falcão; Cristina Garcia-Viguera; Diego
A. Moreno; Luís R. Silva. "Antioxidant and anticancer effects of Prunus avium L. fruits". Trabalho apresentado em IX COLAPLAMED
2021, 2021.
- Ana R. Nunes; Gonçalves, Ana C.; Flores-Félix, José David; Alves, Gilberto; Amílcar Falcão; Luís R. Silva. "Prunus avium
L. by-products valorisation: phenolic composition and biological properties". Trabalho apresentado em IX COLAPLAMED 2021,
2021.
- Nunes, Ana R.; Gonçalves, Ana C.; Flores-Félix, José David; Amílcar Falcão; Cristina García-Viguera; Diego A. Moreno; Alves,
Gilberto; Luís R. Silva. "Bioactive compounds of sweet cherry by-products: assessment of biological properties". Trabalho
apresentado em XVI Annual CICS-UBI Symposium, 2021.
- Mota, Francisco; Saramago, Ana; Matias, Mariana; Ferreira, Octávio; Silvestre, Samuel; Alves, Gilberto; Reis, Catarina; Gaspar,
Maria Manuela. "A nanotechnological approach to improve the therapeutic potential of cytotoxic agents towards colon cancer".
Trabalho apresentado em Congresso Nacional dos Farmacêuticos 2020 e XIV Congresso Mundial dos Farmacêuticos de Língua Portuguesa,
2020.
- Saramago, Ana; Mota, Francisco; Matias, Mariana; Ferreira, Octávio; Silvestre, Samuel; Alves, Gilberto; Reis, Catarina; Gaspar,
Maria Manuela. "Lipid-based nanosystems of Biginelli compounds as a novel therapeutic tool for cancer". Trabalho apresentado
em : Congresso Nacional dos Farmacêuticos 2020 e XIV Congresso Mundial dos Farmacêuticos de Língua Portuguesa, 2020.
- Gonçalves, Joana; Silva, Soraia; Vitorino, Carla; Alves, Gilberto; Fortuna, Ana. "How does the device determine nose-to-brain
drug delivery to mice?". Trabalho apresentado em Drug Delivery to the Lungs, 2019.
- RADHIA AITFELLA LAHLOU; Halladj, F.; Mohammedi, A.; Gonçalves, Ana C.; Nunes, Ana R.; Alves, Gilberto. "Polyphenols, flavonoids,
antioxidant and anticoccidial activities of Rosmarinus officinalis, Thymus algeriensis and Mentha aquatica". Trabalho apresentado
em III International Congress in Health Sciences Research Towards Innovation and Entrepreneurship: Trends in Aging and
Cancer, 2019.
- Gonçalves, Ana; Nunes, Ana; Rodrigues, Márcio; SANTOS, ADRIANA O.; Alves, Gilberto; Silva, Luís. "Effects of saco cherry extracts
on human colon adenocarcinoma Caco-2 cells". Trabalho apresentado em XIV Annual CICS Symposium, 2019.
- Nunes, AR; Gonçalves, AC; Jesus, F; Falcão, A; Silva, LR; Alves, G.. "Phytochemical profile and bioactive properties of Prunus
avium (L.) stems: A cost effective strategy for health improvement?". Trabalho apresentado em Natural Products in Drug
Discovery and Human Health (NatProdDDH), Lisbon, Portugal, 2019.
- Gonçalves, Joana; Silva, Soraia; Bicker, Joana; Alves, Gilberto; Falcão, Amílcar; Fortuna, Ana. "Nose-to-brain delivery of
levetiracetam: preclinical evidence". Trabalho apresentado em 53rd Annual Scientific Meeting of the European Society for
Clinical Investigation, 2019.
- Alves, Gilberto; Meirinho, Sara; Campos, Gonçalo; Fortuna, Ana; Falcão, Amílcar; Rodrigues, Márcio. "Development and validation
of the first HPLC method for quantification of perampanel and stiripentol in mouse matrices using an innovator salting-out
assisted liquid-liquid extraction procedure optimized by a design of experiments approach". Trabalho apresentado em 53rd
Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI 2019), 2019.
- Pires, Patrícia C.; Santos, Liliana; Rodrigues, Márcio; Alves, Gilberto; SANTOS, ADRIANA O.. "Simultaneous quantification
of phenytoin and fosphenytoin in mouse blood and brain using high-performance liquid chromatography: a tool for in vivo studies".
Trabalho apresentado em 6th European Chemical Biology Symposium, 2019.
- Pires, Patrícia C.; Santos, Liliana; Rodrigues, Márcio; Alves, Gilberto; SANTOS, ADRIANA O.. "Novel fosphenytoin formulations
for intranasal administration - development, characterization and in vitro release studies". Trabalho apresentado em 3rd
European Conference on Pharmaceutics, 2019.
- Ferreira, Octávio; Soeiro, P. F.; Silvestre, Samuel; Alves, Gilberto. "Dihydrotriazolopyrimidine derivatives and their cytotoxic
evaluation". Trabalho apresentado em XIV Annual CICS-UBI Symposium, 2019.
- Ferreira, Octávio; Soeiro, P. F.; Amílcar Falcão; Silvestre, Samuel; Alves, Gilberto. "4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidines
as potential anticonvulsant agents and their cytotoxic effect". Trabalho apresentado em III International Congress in Health
Sciences Research – Trends in Aging and Cancer, 2019.
- Brito, Vanessa; Serrano, João L. ; Alves, Gilberto; Almeida, Paulo; Silvestre, Samuel. "4-Azasteroid derivatives as inhibitors
of prostate cells proliferation: study of three-dimensional quantitative structureactivity relationship (3D-QSAR)". Trabalho
apresentado em XXIV Encontro Luso-Galego de Química, 2018.
- Eunice Sofia Aves; Meirinho, Sara; Amílcar Falcão; Rodrigues, Márcio; Alves, Gilberto. "Herb-drug interaction of Paullinia
cupana (guarana) extract on the pharmacokinetics of phenytoin in rats". Trabalho apresentado em IV Congresso Científico
Anual do UBIPharma, 2018.
- Gonçalves, AC; Bento, C; Nunes, AR; Alves, G.; Silva, LR. "Phenolic rich extracts of sweet cherry: antioxidant activity, antidiabetic
potential and erythrocytes protection". Trabalho apresentado em 30th International Symposium on the Chemistry of Natural
Products, Athens, Italy, 2018.
- Nunes, AR; Gonçalves, AC; Jesus, F; Alves, G.; Silva, LR. "Prunus avium (L.) stems as a good therapeutic potential for human
health". Trabalho apresentado em 30th International Symposium on the Chemistry of Natural Products, Athens, Italy,
2018.
- Nunes, AR; Jesus, F; Gonçalves, AC; Alves, G.; Silva, LR. "Effects of phenolic compounds from Prunus avium leaves in Caco-2
cells against t-BHP-induced toxicity". Trabalho apresentado em 4th International Congress on Occupational & Environmental
Toxicology, Matosinhos, Porto, Portugal, 2018.
- Gonçalves, AC; Nunes, AR; Rodrigues, Márcio; O. Santos, A.; Alves, G.; Silva, LR. "Effects of sweet cherry phenolics on human
colon adenocarcinoma Caco-2 cells". Trabalho apresentado em 4th International Congress on Occupational & Environmental
Toxicology, Matosinhos, Porto, Portugal, 2018.
- Ventura, Sandra; Rodrigues, Márcio; Falcão, Amílcar; Alves, Gilberto. "Safety evidence of Citrus aurantium (bitter orange)
extract administration with lamotrigine: pharmacokinetics data from in vivo studies in rats". Trabalho apresentado em XIII
Annual CICS Symposium, 2018.
- Gonçalves, AC; Nunes, AR; Rodrigues, Márcio; O. Santos, A.; Alves, G.; Silva, LR. "Effects of coloured and non-coloured phenolics
of Saco sweet cherries on human colon adenocarcinoma Caco-2 cells". Trabalho apresentado em XIII Annual CICS Symposium,
Covilhã, Portugak, 2018.
- Silva, LR; Gonçalves, AC; Nunes, AR; Bento, C; Alves, G.. "Pterospartum tridentatum: the biological potential of phenolic
compounds". Trabalho apresentado em XIII Annual CICS Symposium, Covilhã, Portugal, 2018.
- Gonçalves, Ana; Nunes, Ana; Alves, Gilberto; Rodrigues, Márcio; Silva, Luís. "Anticarcinogenic effect of saco sweet cherry
extracts on human colon adenocarcinoma Caco-2 cell lines". Trabalho apresentado em 2ª Reunião de Oncologia da Cova da Beira,
2018.
- Gonçalves, AC; Nunes, AR; Rodrigues, Márcio; Alves, G.; Silva, LR. "The anticarcinogenic effect of Saco sweet cherry extracts
on human colon adenocarcinoma Caco-2 cell lines". Trabalho apresentado em II Reunião de Oncologia da Cova da Beira, Centro
Hospitalar Universitário Cova da Beira, 2018.
- Silva, LR; Gonçalves, AC; Nunes, AR; Alves, G.. "The viability effects of phenolics from Pterospartum tridentatum on human
colon adenocarcinoma". Trabalho apresentado em II Reunião de Oncologia da Cova da Beira, Centro Hospitalar Universitário
Cova da Beira, 2018.
- Nunes, AR; Gonçalves, AC; Alves, G.; Silva, LR. "Prunus avium vegetal parts: Can stems be a good therapeutic potential against
cancer cells?". Trabalho apresentado em II Reunião de Oncologia da Cova da Beira, Centro Hospitalar Universitário Cova
da Beira, Covilhã, Portugal, 2018.
- Gonçalves, Ana C.; Alves, Gilberto; Silva, Luís R.. "Biochemical characterization of polyphenol-rich extracts from Saco sweet
cherry". Trabalho apresentado em VI ENEQUI, 2018.
- Ferreira, Octávio; Silvestre, Samuel; Alves, Gilberto. "New lamotrigine-related compounds as potential antiepileptic drugs
and their cytotoxicity evaluation". Trabalho apresentado em XII Annual CICS-UBI Symposium, 2018.
- Magalhães, Paulo; Alves, Gilberto; Llerena, A.; Fortuna, Ana; Falcão, Amílcar; Magalhães, P.; Alves, G.; Fortuna, A.; Falcão,
A.. "Genetic characterization of the CYP2C9, CYP2C19, CYP2D6 isoenzymes and P-glycoprotein in Portuguese depressive patients".
Trabalho apresentado em 47th ESPC Symposium on Clinical Pharmacy, 2018.
- Lourenço, Dina; Sarraguça, Mafalda; Alves, Gilberto; Coutinho, Paula; Araujo, A.R.T.S.; Rodrigues, Márcio. "HPLC-DAD method
for determination of zonisamide in human plasma using microextraction by packed sorbent optimized by Plackett-Burman experimental
design". Trabalho apresentado em 32nd International Epilepsy Congress, 2017.
- Fonseca, Beatriz; Ventura, Sandra; Rodrigues, Márcio; Alves, Gilberto. "A novel HPLC-DAD method for simultaneous quantification
of levetiracetam, zonisamide, lamotrigine, pentylenetetrazole and pilocarpine in rat plasma and brain samples". Trabalho apresentado
em 32nd International Epilepsy Congress, 2017.
- Ferreira, Ana; Rodrigues, Márcio; SANTOS, ADRIANA O.; Fortuna, Ana; Falcão, Amílcar; Alves, Gilberto. "Potential of baicalein,
(-)-epigallocatechin gallate, kaempferol, quercetin and silymarin and their dual combinations in reversing the P-glycoprotein-mediated
antiepileptic drug resistance". Trabalho apresentado em 32nd International Epilepsy Congress, 2017.
- Ferreira, Ana; Rodrigues, Márcio; Falcão, Amílcar; Alves, Gilberto. "Effects of silymarin and (-)-epigallocatechin gallate
on the pharmacokinetics of oxcarbazepine in rats". Trabalho apresentado em 6th Pharmaceutical Sciences World Congress,
2017.
- Ferreira, Ana; Rodrigues, Márcio; Fortuna, Ana; Falcão, Amílcar; Alves, Gilberto. "Effects of the silymarin, a P-glycoprotein
inhibitor, on the pharmacokinetics of oxcarbazepine and its active metabolite licarbazepine". Trabalho apresentado em II
International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship - Trends in Biotechnology for
Biomedical Applications, 2017.
- Ferreira, Ana Filipa; Rodrigues, Márcio; Amílcar Falcão; Alves, Gilberto. "Effects of the silymarin and (-)-epigallocatechin
gallate on the pharmacokinetics of oxcarbazepine in rats". Trabalho apresentado em 6th FIP Pharmaceutical Sciences World
Congress, 2017.
- Jarogniew Luszczki; Amílcar Falcão; Alves, Gilberto; Ferreira, Ana Filipa. "Isobolographic analysis of the neuro and hepatotoxicological
profile resulting from the combination of the antiepileptic drugs carbamazepine, oxcarbazepine or phenytoin with silymarin,
a flavonoid-type P-glycoprotein inhibitor". Trabalho apresentado em II International Congress in Health Sciences Research
Towards Innovation and Entrepreneurship - Trends in Biotechnology, 2017.
- Ferreira, Ana; Rodrigues, Márcio; Fortuna, Ana; Falcão, Amílcar; Alves, Gilberto. "Flavonoids as potential reversing agents
of the pharmacoresistance to antiepileptic drugs mediated by the P-glycoprotein". Trabalho apresentado em 12th European
Congress on Epileptology, 2016.
- Ferreira, Ana Filipa; adriana santos; Amílcar Falcão; Alves, Gilberto. "In vitro synergistic effect of baicalein, (-)-epigallocatechin
gallate, kaempferol, quercetin and silymarin in the inhibition of the P-glycoprotein". Trabalho apresentado em Ciência
2016 - Science and Technology in Portugal Meeting, 2016.
- Pires, Patrícia C.; Canário, Catarina; Matias, Mariana; Brito, Vanessa; SANTOS, ADRIANA O.; Amílcar Falcão; Silvestre, Samuel;
Alves, Gilberto. "Steroidal estrone oximes: cytotoxic effects on hormone-dependent cancer cell lines". Trabalho apresentado
em XI Annual CICS-UBI Symposium, 2016.
- Antunes Viegas, Daniel; Rodrigues, Márcio; Francisco, Joana; Falcão, Amílcar; Alves, Gilberto; SANTOS, ADRIANA O.. "Development
of an ex vivo permeation/bioconversion screening method to support nasal drug product design". Trabalho apresentado em International
Conference of Alternatives to Animal Experimentation, 2015.
- Magalhães, Paulo; Alves, Gilberto; Madeira, Nuno; LLerena, Adrián; Falcão, Amílcar. "Pharmacogenetics in the treatment of
depression: a clinical multicentre study". Trabalho apresentado em Mediterranean advanced course of psychopharmacotherapeutics,
2015.
- Fortuna, Ana; Alves, Gilberto; Bicker, Joana; Falcão, Amílcar. "Development of a new PAMPA method for the prediction of blood-brain
barrier permeation using an in-house brain lipid extract". Trabalho apresentado em 17th International Symposium on Signal
Transduction at the Blood-Brain and Blood-Retina Barriers, 2014.
- Ferreira, Ana; Rodrigues, Márcio; Rosado, Luísa; Rosado, Pedro; Falcão, Amílcar; Alves, Gilberto. "A new MEPS/HPLC-DAD assay
for therapeutic drug monitoring of phenobarbital, phenytoin, carbamazepine, lamotrigine, oxcarbazepine, and their active metabolites
carbamazepine-10,11-epoxide and licarbazepine in human plasma". Trabalho apresentado em 11th European Congress on Epileptology,
2014.
- Magalhães, Paulo; Alves, Gilberto; Rodrigues, Márcio; Llerena, Adrián; Falcão, Amílcar. "First liquid chromatography assay
for the simultaneous determination of venlafaxine and O-desmethylvenlafaxine in human plasma using microextraction by packed
sorbent". Trabalho apresentado em IX Annual CICS Symposium, 2014.
- Fortuna, Ana; Tavares, Ana; Couceiro, Paula; Alves, Gilberto; Falcão, Amílcar. "Medication regimen complexity evaluation in
a hypertensive Portuguese population". Trabalho apresentado em 43rd European Symposium on Clinical Pharmacy, 2014.
- Fortuna, Ana; Magalhães, Paulo; Rodrigues, Marcio; Llerena, A.; Alves, Gilberto; Falcão, Amílcar. "A new MEPS/HPLC assay to
quantify venlafaxine and its main metabolite in human plasma". Trabalho apresentado em 43rd European Symposium on Clinical
Pharmacy, 2014.
- Serralheiro, A.; Alves, G.; Fortuna, A.; Falcão, A.. "Avaliação do potencial da via intranasal para a administração de fármacos
antiepiléticos: Aplicação à carbamazepina". Trabalho apresentado em 26º Encontro Nacional de Epileptologia, 2014.
- Rodrigues, Márcio; Alves, Gilberto; Campos, Gonçalo; Queiroz, João; Falcão, Amílcar. "First liquid chromatographic assay for
determination of amiodarone and its main metabolite in human plasma using microextraction by packed sorbent as sample preparation
procedure". Trabalho apresentado em 47th Annual Scientific Meeting of European Society for Clinical Investigation – ESCI
2013, 2013.
- Ferreira, Ana; Rodrigues, Márcio; Campos, Gonçalo; Falcão, Amílcar; Alves, Gilberto. "Evaluation of drug interactions with
amiodarone using HepaRG cells as experimental model". Trabalho apresentado em 47th Annual Scientific Meeting of European
Society for Clinical Investigation – ESCI 2013, 2013.
- Rodrigues, Márcio; Alves, Gilberto; Campos, Gonçalo; Lourenço, Nulita; Falcão, Amílcar. "Herb-drug interaction of Paullinia
cupana seed extract and amiodarone in rats: a potential risk for reduced bioavailability of amiodarone in clinical practice".
Trabalho apresentado em 47th Annual Scientific Meeting of European Society for Clinical Investigation – ESCI 2013,
2013.
- Ferreira, Ana Filipa; Rodrigues, Márcio; Campos, Gonçalo; Amílcar Falcão; Alves, Gilberto. "Evaluation of drug interactions
with amiodarone using HepaRG cells as experimental model, in: 47th Annual Meeting of the European Journal of Clinical Investigation".
2013.
- Magalhães, Paulo; Freire, Idalina; Falcão, Amílcar; Fonseca, Olímpia; Alves, Gilberto. "Therapeutic drug monitoring of gentamicin:
a retrospective evaluation study". 2013.
- Serralheiro, A.; Alves, G.; Fortuna, A.; Falcão, A.. "The intranasal administration as a potential route for carbamazepine
brain targeting". Trabalho apresentado em IV Conferência CEF 2013, 2013.
- Rodrigues, Márcio; Alves, Gilberto; Lourenço, Nulita; Falcão, Amílcar. "Interação entre os extratos de Fucus vesiculosus e
de Paullinia cupana com a amiodarona em ratos". Trabalho apresentado em Congresso Nacional dos Farmacêuticos 2012,
2012.
- Rodrigues, Márcio; Alves, Gilberto; Lourenço, Nulita; Falcão, Amílcar. "Pharmacokinetic interaction of Paullinia cupana extract
and amiodarone in rat". Trabalho apresentado em Conferência CEF 2012, 2012.
- Fortuna, Ana; Alves, Gilberto; Soares-Da-Silva, Patrício; Falcão, Amílcar. "In vitro screening and in vivo preclinical models
fo r pharmacokinetic evaluation of carbamazepine and derivatives". Trabalho apresentado em Conferência Centro de Estudos
Farmacêuticos (CEF), 2012.
- Sousa, Joana; Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "Quantification of ciprofloxacin in plasma and nasal mucosa
matrices by high-performance liquid chromatography with fluorescence detection". Trabalho apresentado em 6th European Congress
of Pharmacology, EPHAR, 2012.
- Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "A new parallel artificial membrane permeability assay for estimation of intestinal
absorption and protein binding in drug discovery programs". Trabalho apresentado em 6th European Congress of Pharmacology,
EPHAR 20 12, 2012.
- Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "Development of an in vitro bidirectional transport model for prediction of
human drug absorption and assessment of P-glycoprotein involvement in intestinal drug absorption.". Trabalho apresentado em
6th European Congress of Pharmacology, EPHAR, 2012.
- Fortuna, Ana; Alves, Gilberto; Soares-Da-Silva, Patrício; Falcão, Amílcar. "Influence of plasma protein binding and efflux
transport mediated by P-glycoprotein on the enantioselective biodisposition of eslicarbazepine and R-licarbazepine.". Trabalho
apresentado em 6th European Congress of Pharmacology, EPHAR, 2012.
- Fortuna, Ana; Alves, Gilberto; Soares-Da-Silva, Patrício; Falcão, Amílcar. "Plasma and brain pharmacokinetic profiles of carbamazepine
and nine derivatives after oral administration to mice: implications for selection of drug candidates.". Trabalho apresentado
em 6th European Congress of Pharmacology, EPHAR, 2012.
- Rodrigues, Márcio; Matias, Mariana; Canário, Catarina; Abrantes, João; Ferreira, Ana; Alves, Gilberto; Falcão, Amílcar. "Herb-drug
interaction: effect of Fucus vesiculosus extract on the bioavailability and disposition of amiodarone in rats". Trabalho apresentado
em 6th European Congress of Pharmacology – EPHAR 2012, 2012.
- Rodrigues, Márcio; Canário, Catarina; Matias, Mariana; Abrantes, João; Ferreira, Ana; Alves, Gilberto; Falcão, Amílcar. "Effects
of Paullinia cupana (Guarana) seed extract on the systemic exposure of amiodarone in rats". Trabalho apresentado em 6th
European Congress of Pharmacology – EPHAR 2012, 2012.
- Fortuna, Ana; Alves, Gilberto; Soares-Da-Silva, Patrício; Falcão, Amílcar. "Avaliação farmacométrica in silico, in vitro e
in viv o da carbamazepina e análogos estruturais.". Trabalho apresentado em 24º Encontro Nacional de Epileptologia,
2012.
- Serralheiro, A.; Alves, G.; Fortuna, A.; Falcão, A.. "Fast HPLC-UV method for the simultaneous determination of carbamazepine,
lamotrigine, oxcarbazepine and phenytoin in mouse plasma, brain and liver tissues". Trabalho apresentado em 6th European
Congress of Pharmacology, 2012.
- Serralheiro, A.; Alves, G.; Fortuna, A.; Falcão, A.. "Development of a new HPLC-UV method for the simultaneous quantification
of four antiepileptic drugs and their main metabolites in mouse liver homogenates". Trabalho apresentado em Congresso Nacional
dos Farmacêuticos, 2012.
- Rodrigues, Márcio; Alves, Gilberto; Bicker, Joana; Ferreira, Ana; Queiroz, João; Falcão, Amílcar. "A simple procedure for
the monitoring of amiodarone and desethylamiodarone by HPLC-DAD detection: application to clinical toxicology". Trabalho apresentado
em I Jornadas Ibéricas de Toxicologia, 2011.
- Rodrigues, Márcio; Alves, Gilberto; Bicker, Joana; Ferreia, Ana; Queiroz, João; Falcão, Amílcar. "Fast HPLC-DAD method for
the determination of amiodarone and desethylamiodarone in liver, kidney and lung tissues of rat". Trabalho apresentado em
IV Congresso Ibero-Americano de Ciências Farmacêuticas, 2011.
- Sousa, Joana; Alves, Gilberto; Fortuna, Ana; Falcão, Amílcar. "Determination of norfloxacin, ciprofloxacin and lemofloxacin
in hum an plasma by a simple and rapid liquid chromatographic method.". Trabalho apresentado em Conferência Ibero-Americana
de Faculdades de Farmácia, 2011.
- Fortuna, Ana; Bicker, Joana; Mesquita, Inês; Alves, Gilberto; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Development of
an enantioselective high performance liquid chromatography analysis of dibenz[b,f]azepine-5- carboxamide derivatives in mouse
plasma and brain.". Trabalho apresentado em Conferência Ibero-Americana de Faculdades de Farmácia, 2011.
- Fortuna, Ana; Bicker, Joana; Mesquita, Inês; Alves, Gilberto; Falcão, Amílcar; Soares-Da-Silva, Patrício. "A rapid and robust
HPLC-UV method for simultaneous quantification of three generations of anti-epileptic drugs in human plasma: carbamazepine,
oxcarbazepine and eslicarbazepine acetate.". Trabalho apresentado em Conferência Ibero-Americana de Faculdades de Farmácia,
2011.
- Fortuna, Ana; Bicker, Joana; Mesquita, Inês; Alves, Gilberto; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Assessment of the
involvement of P-glycoprotein in intestinal drug absorption during drug discovery". Trabalho apresentado em Conferência
Ibero-Americana de Faculdades de Farmácia, 2011.
- Rodrigues, Márcio; Alves, Gilberto; Bicker, Joana; Ferreira, Ana; Queiroz, João; Falcão, Amílcar. "Simultaneous determination
of amiodarone and desethylamiodarone by HPLC-DAD in plasma and heart tissue of rat". Trabalho apresentado em IV Congresso
Ibero-Americano de Ciências Farmacêuticas, 2011.
- Serralheiro, A.; Bicker, J.; Fortuna, A.; Alves, G.; Falcão, A.. "Drug monitoring and clinical toxicology: A simple procedure
for the monitoring of six antiepileptic drugs by HPLC-UV detection". Trabalho apresentado em I Jornadas de Toxicologia,
2011.
- Fortuna, Ana; Direito, Rosa; Alves, Gilberto; Sousa, Joana; Falcão, Amílcar; Cabrita, A.. "Morphological evaluation of rat
liver tissue after the subcutaneous injection of 1,2-dimethylhydrazine". Trabalho apresentado em WorldPharma2010 – 16th
IUPHAR World Congress on Basis and Clinical Pharmacology, 2010.
- Fortuna, Ana; Alves, Gilberto; Santos, L.; Falcão, Amílcar; Soares-Da-Silva, Patrício. "A rapid and sensitive high-performance
liquid chromatographic method to quantify carbamazepine, oxcarbazepine, eslicarbazepine acetate and their main metabolites
in human plasma.". Trabalho apresentado em WorldPharma2010 – 16th IUPHAR World Congress on Basis and Clinical Pharmacology,
2010.
- Serralheiro, Ana ; Alves, Gilberto; Nunes, T.; Fortuna, Ana; Rodrigues, Márcio; Falcão, Amílcar; Soares-da-Silva, P.. "Plasma-brain
distribution of licarbazapine enantiomers in mice on steady-state conditions". Trabalho apresentado em 38th American College
of Clinical Pharmacology Annual Meeting, 2009.
- Castel-Branco, M.M.; Alves, Gilberto; Figueiredo, Isabel V.; Falcão, A.C.; Caramona, Margarida M.. "Animal models of seizures
induction in the preclinical assessment of new antiepileptic drugs: the maximal electroshock seizure model (MES test).". Trabalho
apresentado em 1st SPCAL Meeting, 2009.
- Caramona, Margarida; Fortuna, Ana; Alves, Gilberto; Pereira, C.; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Human plasma
protein binding of S- and R-licarbazepine". Trabalho apresentado em XVIII CONGRESO de la Asociación Latinoamericana de
Farmacología; XXX Reunión Anual Socie dad de Farmacología de Chile; XXIII Sociedad Chilena de Ciencias Fisiológicas; III Congreso
Iberoamericano de Farmacología., 2009.
- Alves, G.; Fortuna, A.; Rocha, M.; Serralheiro, A.; Rodrigues, M.; Falcão, A.; Caramona, M.. "Therapeutic drug monitoring
of oxcarbazepine in epileptic patients on carbamazepine therapy". Trabalho apresentado em 38th European Symposium on Clinical
Pharmacy, 2009.
- Caramona, Margarida M.; Alves, Gilberto; Pereira, C.; Falcão, A.C.; Figueiredo, Isabel V.; Castel-Branco, M.M.; Soares-da-Silva,
P.. "Enantioselective disposition of S-licarbazepine and R-licarbazepine in mice after oral administration.". Trabalho apresentado
em [XVIII Congress of the Latin American Association of Pharmacology], 2008.
- Fortuna, Ana; Pires, Ana; Silva, R.; Gaio, Daniel; Alves, Gilberto; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Plasma protein
binding of licarbazepine enantiomers in human and mouse species.". Trabalho apresentado em 1st International Epilepsy Colloquium,
2008.
- Alves, G.L.; Falcão, A.C.; Figueiredo, Isabel V.; Castel-Branco, M.M.; Caramona, Margarida M.; Soares-Da-Silva, P.. "Estereoseletividade
na distribuição plasma-cérebro dos enantiómeros S-licarbazepina e R-licarbazepina no murganho.". Trabalho apresentado em 20º
Encontro Nacional de Epileptologia., 2008.
- Alves, G.L.; Falcão, A.C.; Figueiredo, Isabel V.; Castel-Branco, M.M.; Caramona, Margarida M.; Soares-Da-Silva, P.. "Biodisposição
do acetato de eslicarbazepina no murganho e exposição cerebral aos seus metabolitos.". Trabalho apresentado em 20º Encontro
Nacional de Epileptologia, 2008.
- Fortuna, Ana; Caramona, Margarida; Alves, Gilberto; Pereira, C.; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Binding of licarbazepine
enantiomers to human serum albumin and alpha-1-a cid glycoprotein.". Trabalho apresentado em XVIII CONGRESO de la Asociación
Latinoamericana de Farmacología; XXX Reunión Anual Socie dad de Farmacología de Chile; XXIII Sociedad Chilena de Ciencias
Fisiológicas; III Congreso Iberoamericano de Farmacología., 2008.
- Almeida, Anabela; Fortuna, Ana; Pires, Anaisa; Gaio, Daniel; Silva, R.; Silva, H.; Alves, Gilberto; Falcão, Amílcar. "Lamotrigine
in patients submitted to video-electroencephalographic monitoring : effect of co-medication in temporal and extratemporal
epilepsy". Trabalho apresentado em 1st International Epilepsy Colloquium., 2007.
- Alves, Gilberto; Figueiredo, I.; Castel-Branco, M.; Loureiro, A. I.; Fortuna, Ana; Falcão, Amílcar; Caramona, Margarida. "Enantioselective
HPLC-UV Assay for Eslicarbazepine Acetate (BIA 2-093) and its metabolites determination in mice plasma and tissues: application
to pharmacokinetic studies.". Trabalho apresentado em Pharmaceutical Sciences World Congress (PSWC) – 3rd World Congress
of the Board of Pharmaceutical Sciences of FIP., 2007.
- Alves, G.L.; Figueiredo, I. V.; Falcao, A. C.; Castel-Branco, M.M.; Caramona, Margarida M.. "Stereoselective determination
of eslicarbazepine acetate and its metabolites in mouse liver by HPLC-UV.". Trabalho apresentado em 8th EILAT Conference
on New Antiepileptic Drugs, 2006.
- Machado, S. M.; Castel-Branco, M.M.; Alves, G.L.; Figueiredo, Isabel V.; Falcão, A.C.; Caramona, Margarida M.. "Interaction
of lamotrigine with oxcarbazepine in the maximal electroshock seizure test in rats: an isobolographic analysis.". Trabalho
apresentado em 4th Meeting of the Federation of the European Pharmacological Societies – EPHAR 2004, 2004.
|
| Pré-impressão |
- Ikbel Benalaya; Gilberto Alves; João Lopes; Luís R. Silva. "A Review of Natural Polysaccharides: Sources, Characteristics,
Properties, Food and Pharmaceutical Applications". 2023. https://doi.org/10.20944/preprints202312.1862.v1.
10.20944/preprints202312.1862.v1
- Ana C. Gonçalves; Amícal Falcão; Gilberto Alves; João A. Lopes; Luís R. Silva. "Employ of Anthocyanins in nanocarriers for
Nano Delivery: In Vitro and In Vivo Experimental Approaches for Chronic Diseases". 2022.
https://doi.org/10.20944/preprints202210.0142.v1.
10.20944/preprints202210.0142.v1
|
| Resumo em conferência |
- Meirinho, Sara; Rodrigues, Márcio; SANTOS, ADRIANA O.; Amílcar Falcão; Alves, Gilberto. "Intranasal administration promotes
perampanel rostral-caudal brain distribution with improvement inin vivo anxyolitic activity". Trabalho apresentado em XVII
International CICS-UBI Symposium, 2022.
- Meirinho, Sara; Gomes, Maria; Catarina Ferreira; Caetano Oliveira, Rui; SANTOS, ADRIANA O.; Fortuna, Ana; Amílcar Falcão;
Alves, Gilberto. "Nose-to-brain delivery of perampanel using a non-toxic self-microemulsion drug delivery system.". Trabalho
apresentado em 52ª Reunião da Sociedade Portuguesa de Farmacologia, 40ª Reunião de Farmacologia Clínica e 21ª Reunião
de Toxicologia, Porto, 2022.
- Meirinho, Sara; Rodrigues, Márcio; SANTOS, ADRIANA O.; Amílcar Falcão; Alves, Gilberto. "Nose-to-brain delivery of stiripentol
microemulsions as a promissing alternative to the oral route". Trabalho apresentado em XVI Annual CICS-UBI Symposium,
2021.
- Meirinho, Sara; Rodrigues, Márcio; SANTOS, ADRIANA O.; Fortuna, Ana; Amílcar Falcão; Alves, Gilberto. "Nose-to-brain delivery
of perampanel: a promising therapeutic approach for epilepsy". Trabalho apresentado em 51st Meeting of the Portuguese Society
of Pharmacology, 39th Meeting of the Clinical Pharmacology and 20th Meeting of the Toxicology, Lisboa, 2021.
- Gonçalves, Ana C.; Flores-Félix, José David; Nunes, Ana R.; Falcão, Amílcar C.; Alves, Gilberto; Silva, Luís R.. "Phytochemical
composition and influence of phenolic on the biological potential of sweet cherries". Trabalho apresentado em XVI Annual
CICS-UBI Symposium 2021, Covilhã, 2021.
Publicado
- Flores-Félix, José David; Gonçalves, Ana C.; Nunes, Ana R.; Silva, Luís R.; Alves, Gilberto. "Bacterial biofertilizers as
tool for improvement of blueberry quality and production". Trabalho apresentado em XVI Annual CICS-UBI Symposium, Covilhã,
2021.
Publicado
- Gonçalves, Ana C.; Campos, G; Alves, Gilberto; Garcia-Viguera, Cristina; Moreno, Diego A.; Silva, Luís R.. "Physical, phytochemical
composition and biological potential of Portuguese sweet cherries.". Trabalho apresentado em 6th International Conference
on Food Chemistry and Technology (FCT 2020), Paris, 2020.
- Gonçalves, Ana C.; Nunes, Ana R,; Rodrigues, Márcio; SANTOS, ADRIANA O.; Alves, Gilberto; Nunes, Ana R.; Alves, Gilberto;
Silva, Luís R.. "Sweet cherries phenolic-rich fractions exhibit anti-cancer properties and can modulate P-glycoprotein activity".
Trabalho apresentado em III International Congress in Health Sciences Research Towards Innovation and Entrepreneurship:
Trends in Aging and Cancer, Covilhã, 2019.
Publicado
- Gonçalves, Ana C.; Nunes, Ana R.; Pinto, Edgar; Almeida, Agostinho; Moreno, Diego; Alves, Gilberto; Silva, Luís R.. "Phenolic
composition, minerals and biological potential of Saco sweet cherry". Trabalho apresentado em Natural Products in Drug
Discovery and Human Health (NatProdDDH), Lisboa, 2019.
Publicado
- Nunes, Ana R.; Gonçalves, Ana C.; Falcão, Amílcar; Alves, Gilberto; Silva, Luís R.. "Prunus avium (L). Leaves: an unexplored
source of phenolic compounds". Trabalho apresentado em XIV Annual CICS-UBI Symposium, Covilhã, 2019.
Publicado
- Meirinho, Sara; Fortuna, Ana; Rodrigues, Márcio; Falcão, Amílcar; Alves, Gilberto. "Development and validation of the first
HPLC-DAD method for rufinamide quantification in mouse plasma and tissues with focus on future pharmacokinetic studies.".
Trabalho apresentado em XLIX Reunião da Sociedade Portuguesa de Farmacologia, Porto, 2019.
- Gonçalves, Ana C.; Nunes, Ana R.; Pinto, E.; Almeida, A.; Alves, G.; Silva, Luís R.. "Physicochemical characteristics, chemical
constituents and health-promoting properties of sweet cherries from Fundão region (Portugal)". Trabalho apresentado em XIII
Annual CICS Symposium, Covilhã, 2018.
Publicado
- Nunes, Ana R.; Gonçalves, Ana C.; Jesus, Fábio; Alves, Gilberto; Silva, Luís R.; Gonçalves, Ana C.; Alves, G.. "The biological
potential of phenolic compounds of Prunus avium L. stems". Trabalho apresentado em XIII Annual CICS-UBI Symposium,
Covilhã, 2018.
Publicado
- Magalhães, Paulo; Alves, Gilberto; Llerena, Adrián; Fortuna, Ana; Falcão, Amílcar. "Genetic characterization of the CYP2C9,
CYP2C19, CYPD6 isoenzymes and P-glycoprotein in portuguese patients with depression". Trabalho apresentado em 47th European
Symposium on Clinical Pharmacy, Belfast, Northern Ireland, 2018.
10.1007/s11096-018-0759-9
- Meirinho, Sara; Fortuna, Ana; Rodrigues, Márcio; Falcão, Amílcar; Alves, Gilberto. "Novel bioanalytical method for the quantification
of rufinamide in mouse plasma and tissues using HPLC-DAD: a tool to perform pharmacokinetic studies.". Trabalho apresentado
em XIII Annual CICS-UBI Symposium 2018, Covilhã, 2018.
- Magalhães, Paulo; De Andrés, Fernando; Falcão, Amílcar; LLerena, Adrián; Alves, Gilberto. "In vivo assessment of the CEIBA
cocktail in wistar rats". Trabalho apresentado em XLVI Reunião da Sociedade Portuguesa de Farmacologia, 2016.
- Rocha SM; Saraiva, T.; Cristóvão, Ana Clara; Ferreira, R.; Santos, T.; Esteves, M.; Saraiva, C.; et al. "Histamine modulates
dopaminergic neuronal survival by boosting microglial activity". Trabalho apresentado em 44th Annual Meeting of the European-Histamine-Research-Society
(EHRS), 2015.
Publicado
- Magalhães, Paulo; Alves, Gilberto; Rodrigues, Márcio; Llerena, Adrián; Falcão, Amílcar. "A HPLC-FLD method for the simultaneous
determination of venlafaxine and O-desmethylvenlafaxine in human plasma using microextraction by packed sorbent". Trabalho
apresentado em Reunião Anual da Sociedade Portuguesa de Farmacologia, 2014.
- Marques, R.; Vaz, C.V.; Maia, C.J..; Gama, Adelina; Alves, G.; Schmitt, F.; Santos, C.R.; Socorro, S. "Transgenic rats overexpressing
Regucalcin display lower-susceptibility to develop DMBA-induced mammary gland tumors.". Trabalho apresentado em 13th Young
Scientists Forum (YSF)/38th FEBS Congres, St Petersburg, Russia, 2013.
- Serralheiro, A.; Alves, G.; Fortuna, A.; Falcão, A.. "Analysis of carbamazepine, lamotrigine, oxcarbazepine, phenytoin and
some metabolites in mice brain tissue by high performance liquid chromatography". Trabalho apresentado em 47th Annual Scientific
Meeting of the European Society for Clinical Investigation, Albufeira, 2013.
Publicado • 10.1111/eci.12088
- Serralheiro, A.; Alves, G.; Fortuna, A.; Falcão, A.. "A new assay to quantify carbamazepine, lamotrigine, oxcarbazepine, phenytoin
and their main metabolites in mouse liver homogenates by high performance liquid chromatography coupled with ultraviolet detection".
Trabalho apresentado em 47th Annual Scientific Meeting of the European Society for Clinical Investigation, Albufeira,
2013.
Publicado • 10.1111/eci.12088
- Serralheiro, A.; Bicker, J.; Fortuna, A.; Alves, G.; Falcão, A.. "Novel HPLC-UV method to monitor plasma concentrations of
six antiepileptic drugs and three of their main metabolites in patients with epilepsy". Trabalho apresentado em IV Congresso
Ibero-Americano de Ciências Farmacêuticas, Lisboa, 2011.
Publicado
- Alves, G.; Nunes, T.; Fortuna, A.; Serralheiro, A.; Rodrigues, M.; Falcão, A.; Soares-da-Silva, P.. "Kidney drug exposure
after multiple-dose administration of S- and R-licarbazepine to mice". Trabalho apresentado em 38th American College of
Clinical Pharmacology Annual Meeting, San Antonio (Texas), 2009.
Publicado • 10.1177/00912700090490091001
- Alves, G.; Nunes, T.; Fortuna, A.; Serralheiro, A.; Rodrigues, M.; Falcão, A.; Soares-da-Silva, P.. "Metabolism and liver
pharmacokinetics of S- and R-licarbazepine in mice at the steady-state". Trabalho apresentado em 38th American College
of Clinical Pharmacology Annual Meeting, San Antonio (Texas), 2009.
Publicado • 10.1177/00912700090490091001
- Alves, G.; Nunes, T.; Fortuna, A.; Serralheiro, A.; Rodrigues, M.; Falcão, A.; Soares-da-Silva, P.. "Plasma-brain distribution
of licarbazepine enantiomers in mice on steady-state conditions". Trabalho apresentado em 38th American College of Clinical
Pharmacology Annual Meeting, San Antonio (Texas), 2009.
Publicado • 10.1177/00912700090490091001
- Caramona, Margarida M.; Alves, G.L.; Pereira, C.; Falcão, A.C.; Figueiredo, Isabel V.; Castel-Branco, M. M.; Soares-da-Silva,
P.. "Enantioselective disposition of S-licarbazepine in mice after oral administration.". Trabalho apresentado em [XXX
Annual Congress of the Society of Pharmacology of Chile] - Revista de Farmacología de Chile., Coquimbo, 2008.
Publicado
- Caramona, Margarida M.; Alves, G.L.; Pereira, C.; Falcão, A.C.; Figueiredo, Isabel V.; Castel-Branco, M. M.; Soares-da-Silva,
P.. "Brain pharmacokinetics and chiral discrimination of licarbazepine enantiomers in mice at the blood-brain barrier level.".
Trabalho apresentado em [XXX Annual Congress of the Society of Pharmacology of Chile] - Revista de Farmacología de Chile.,
Coquimbo, 2008.
Publicado
- Alves, G.L.; Falcão, A.C.; Figueiredo, Isabel V.; Castel-Branco, M. M.; Caramona, Margarida M.; Soares-da-Silva, P.. "Relationship
between plasma and brain pharmacokinetic profiles of eslicarbazepine acetate metabolites in mice.". Trabalho apresentado em
21st ECNP Congress - European Neuropsychopharmacology., Barcelona, 2008.
Publicado
- Alves, G.L.; Falcão, A.C.; Figueiredo, Isabel V.; Castel-Branco, M. M.; Caramona, Margarida M.; Soares-da-Silva, P.. "Metabolic
profile of eslicarbazepine acetate in mice and the role of liver in the systemic drug exposure.". Trabalho apresentado em
21st ECNP Congress - European Neuropsychopharmacology., Barcelona, 2008.
Publicado
- Alves, G.L.; Falcão, A.C.; Figueiredo, Isabel V.; Castel-Branco, M. M.; Caramona, Margarida M.; Soares-da-Silva, P.. "[Biodisposition
of eslicarbazepine acetate in the mouse and brain exposure to its metabolites.]". Trabalho apresentado em [20th National
Meeting of Epileptology] - Sinapse, Lisboa, 2008.
Publicado
- Alves, G.L.; Falcão, A.C.; Figueiredo, Isabel V.; Castel-Branco, M. M.; Caramona, Margarida M.; Soares-da-Silva, P.. "[Stereoselectivity
in the plasma-brain distribution of the S-licarbazepine and R-licarbazepine enantiomers in the mouse.]". Trabalho apresentado
em [20th National Meeting of Epileptology] - Sinapse, Lisboa, 2008.
Publicado
- Machado, S. M.; Castel-Branco, M. M.; Alves, G.L.; Figueiredo, Isabel V.; Falcão, A.C.; Caramona, Margarida M.. "Interaction
of lamotrigine with oxcarbazepine in the maxmal electroshock seizure test in rats: an isobolographic analysis.". Trabalho
apresentado em 4th EPHAR Congress - Fund. Clin. Pharmacol., Porto, 2004.
Publicado
- Lebre, V. L.; Castel-Branco, M. M.; Alves, G.L.; Figueiredo, Isabel V.; Falcão, A.C.; Caramona, Margarida M.. "Assessment
of the relationship between lamotrigine plasma and brain profiles and its anticonvulsant effect in rats.". Trabalho apresentado
em 4th EPHAR Congress - Fund. Clin. Pharmacol, Porto, 2004.
Publicado
- Castel-Branco, M. M.; Lebre, V. L.; Alves, G.L.; Figueiredo, Isabel V.; Falcão, A.C.; Caramona, Margarida M.. "Lamotrigine
pharmacokinetic/pharmacodynamic (PK/PD) modelling.". Trabalho apresentado em 4th EPHAR Congress - Fund. Clin. Pharmacol.,
Porto, 2004.
Publicado
- Machado, S. M.; Castel-Branco, M. M.; Alves, G.L.; Figueiredo, Isabel V.; Falcão, A.C.; Caramona, Margarida M.. "[Evaluation
of the interaction between lamotrigine and oxcarbazepine in rats through an isobolographic analysis.]". Trabalho apresentado
em [16th National Meeting of Epileptology] - Sinapse, Lisboa, 2004.
Publicado
|
| Tese / Dissertação |
- Alves, Eunice Sofia Faria dos Santos. "Efeito do extrato de Paullinia cupana na farmacocinética da fenitoína em ratos Wistar".
Mestrado, 2019. http://hdl.handle.net/10400.6/8924.
- Ventura, Sandra Cristina do Espírito Santo. "Nonclinical assessment of the potential for herb-drug interactions between herbal
extracts present in weight loss supplements and lamotrigine". Doutoramento, 2019. http://hdl.handle.net/10400.6/6973.
- Fonseca, Beatriz Marques da. "Bioanalytical tools for unraveling part of the puzzle of the biochemical phenomena in epilepsy:
neuromediators and antiepileptic drugs". Doutoramento, 2019. http://hdl.handle.net/10400.6/6966.
- Ferreira, Joana Giesteira. "Otimização de formulações termorreversíveis para administração nasal de carbamazepina". Mestrado,
2018. http://hdl.handle.net/10400.6/8747.
- Matias, Mariana Ruivo; Alves, Gilberto Lourenço; Silvestre, Samuel Martins; Ferreira, Amílcar Celta Falcão Ramos. "Development
of new antiepileptic drug candidates: a set of lamotrigine-related compounds". Doutoramento, 2018. http://hdl.handle.net/10400.6/4769.
- Sousa, Joana Maria Ramalho de Almeida e; Ferreira, Amílcar Celta Falcão Ramos; Alves, Gilberto Lourenço. "Evaluation of intranasal
administration of fluoroquinolones and their potential in the treatment of chronic rhinosinusitis: ciprofloxacin and levofloxacin".
Doutoramento, 2018. http://hdl.handle.net/10316/42556.
- Aparício, Joana Bicker de Melo Alves; Falcão, Amílcar; Alves, Gilberto. "A Screening Strategy for Evaluation of Drug Transport
across the Blood-Brain Barrier: Application to Catechol-O-methyltransferase Inhibitors, Dopamine ß-hydroxylase Inhibitors
and Dibenz[b,f]azepine-5-carboxamide Derivatives". Doutoramento, 2018. http://hdl.handle.net/10316/42543.
- Ferreira, Ana Filipa da Silva; Alves, Gilberto Lourenço; Ferreira, Amílcar Celta Falcão Ramos. "Coadministration of antiepileptic
drugs and P-glycoprotein inhibitors of flavonoid-type". Doutoramento, 2018. http://hdl.handle.net/10400.6/4775.
- Alves, Gilberto; Falcão, Amílcar; Gonçalves, Daniela de Oliveira. "Non-clinical Evaluation of the Pharmacokinetics and Pharmacodynamics
of Opicapone, a Novel Catechol-O-methyltransferase Inhibitor". Doutoramento, 2017. http://hdl.handle.net/10316/79620.
- Amante, Pedro Miguel Lima Sobral. "Doença maníaco-depressiva: uma patologia psiquiátrica intrigante". Mestrado, 2017. http://hdl.handle.net/10400.6/7938.
- Ferreira, Paulo Renato da Silva. "Possibilidade de indução de cancro pelo tacrolímus". Mestrado, 2017. http://hdl.handle.net/10400.6/7937.
- Santos, Carmo Isabel Costa Fernandes Madaleno dos. "A funcionalização de esteroides com heterociclos no desenvolvimento de
potenciais inibidores da glicoproteína-P". Mestrado, 2017. http://hdl.handle.net/10400.6/7949.
- Vicente, Nuno Tavares. "Caraterização sociodemográfica, clínica e farmacoterapêutica de doentes com epilepsia seguidos em
consulta externa de neurologia". Mestrado, 2017. http://hdl.handle.net/10400.6/7936.
- Fernandes, Ana Cristina Moura Xavier. "Monitorização terapêutica de fármacos com base nos princípios de farmacocinética clínica".
Mestrado, 2017. http://hdl.handle.net/10400.6/7929.
- Alves, Gilberto Lourenço; Ferreira, Ana Filipa da Silva; Gomes, Ana Inês Pacheco Vaz. "In vitro assessment of cytochrome P450
2C9 inhibition: tolbutamide as probe substrate and HepaRG cells as human hepatic model". Mestrado, 2016. http://hdl.handle.net/10400.6/5808.
- Rebelo, Ana Isabel Cunha; Alves, Gilberto Lourenço. "Alterações farmacocinéticas e suas implicações em estados de obesidade
mórbida em adultos. Experiência Profissionalizante na vertente de Farmácia Comunitária, Hospitalar e Investigação". Mestrado,
2016. http://hdl.handle.net/10400.6/6282.
- Serralheiro, Ana Isabel Azevedo; Falcão, Amílcar; Alves, Gilberto. "Intranasal Delivery of Antiepileptic Drugs: Non-clinical
Evaluation of Pharmacokinetics and Brain Biodistribution". Doutoramento, 2016. http://hdl.handle.net/10316/29482.
- Alves, Gilberto Lourenço; Pires, Benedita Nunes. "Necrólise epidérmica tóxica induzida por fármacos". Mestrado, 2015. http://hdl.handle.net/10400.6/4941.
- Alves, Gilberto Lourenço; Lopes, Ricardo José Castro Bastos. "Foto-onicólise induzida por fármacos: uma visão geral". Mestrado,
2015. http://hdl.handle.net/10400.6/5334.
- Alves, Gilberto Lourenço; Santos, Adriana; Santos, Rui Pedro da Silva. "Desenvolvimentos na administração intranasal de antipsicóticos:
aspetos farmacêuticos, farmacocinéticos e farmacodinâmicos". Mestrado, 2015. http://hdl.handle.net/10400.6/5276.
- Alves, Gilberto Lourenço; Rodrigues, Márcio; Marques, Alexandre Emanuel Ramos. "Aplicação de MEPS em bioanálise de amostras
de tecidos". Mestrado, 2015. http://hdl.handle.net/10400.6/5277.
- Alves, Gilberto Lourenço; Rodrigues, Márcio; Marvanejo, Patricia Sofia Draque. "Métodos cromatográficos para a quantificação
de sondas da glicoproteína-P". Mestrado, 2015. http://hdl.handle.net/10400.6/5278.
- Alves, Gilberto Lourenço; Santos, Flávia Patrícia Andrade. "Estudo e caracterização dos hábitos de compra de medicamentos
e suplementos online em Portugal". Mestrado, 2015. http://hdl.handle.net/10400.6/5280.
- Alves, Gilberto Lourenço; Serralheiro, Ana; Meirinho, Sara Alexandra. "Bioanalytical method validation of Venlafaxine and
Desvenlafaxine in mouse plasma, brain and liver using a MEPS/HPLC assay: a path to study these drugs’ intranasal administration".
Mestrado, 2015. http://hdl.handle.net/10400.6/6438.
- Almeida, Anabela Antunes de; Alves, Gilberto Lourenço; Ferreira, Teresa de Jesus Santos. "Reflexão sobre erros de medicação
na aferição da qualidade dos Cuidados de Saúde". Mestrado, 2015. http://hdl.handle.net/10400.6/5043.
- Alves, Gilberto Lourenço; Mota, Nadine Freitas. "Análise do folheto informativo de medicamentos não sujeitos a receita médica
para afeções comuns do trato gastrointestinal". Mestrado, 2015. http://hdl.handle.net/10400.6/5140.
- Ferreira, Maria João da Silva; Alves, Gilberto Lourenço. "Polimedicação em idosos institucionalizados". Mestrado, 2015. http://hdl.handle.net/10400.6/5328.
- Silva, Joana Madeira da; Alves, Gilberto Lourenço; Queimado, Sandra Isabel da Silva. "Operacionalização dos Critérios STOPP/START
e sua Aplicação em Idosos sob Terapia Anticoagulante". Mestrado, 2015. http://hdl.handle.net/10400.6/5442.
- Nunes, Daniela Sofia Vieira; Alves, Gilberto Lourenço. "Evidência de efeitos cancerígenos e anticancerígenos associados à
Amiodarona". Mestrado, 2015. http://hdl.handle.net/10400.6/5106.
- Moreira, Isabel Sofia Lourenço. "Desenvolvimento de uma solução autoemulsionante de fenitoína para administração oral". Mestrado,
2015. http://hdl.handle.net/10400.6/7168.
- Freitas, Sílvia Vanessa Spínola; Alves, Gilberto Lourenço. "Cardiotoxicidade induzida por fármacos". Mestrado, 2015. http://hdl.handle.net/10400.6/4983.
- Alves, Gilberto Lourenço; Agostinho, André Filipe Chambel. "Caracterização do perfil de consumo de ansiolíticos, sedativos
e hipnóticos na Beira Interior". Mestrado, 2014. http://hdl.handle.net/10400.6/5144.
- Alves, Gilberto Lourenço; Castelo-Branco, Miguel; Pousinho, Sarah Jane. "Deteção e análise de casos de nefrotoxicidade induzida
por fármacos ou outras substâncias medicinais". Mestrado, 2014. http://hdl.handle.net/10400.6/4984.
- Alves, Gilberto Lourenço; Serra, António Luís; Tomás, Carina Alexandra Gomes. "Aplicação dos critérios STOPP/START a idosos
diabéticos em Cuidados de Saúde Primários". Mestrado, 2014. http://hdl.handle.net/10400.6/5047.
- Alves, Gilberto Lourenço; Silvestre, Samuel Martins; Esteves, Davide Miguel Pires. "Antidiabéticos orais: perfil de utilização,
efeitos secundários e interações medicamentosas". Mestrado, 2014. http://hdl.handle.net/10400.6/5055.
- Gonçalves, Miguel Ângelo Lopes; Alves, Gilberto; Santos, Adriana Oliveira dos. "Modelos ex-vivo para avaliação da permeação
de fármacos pelas vias nasal e rectal – revisão sistemática". Mestrado, 2014. http://hdl.handle.net/10400.6/6413.
- Diogo, Carla Alexandra Santos; Alves, Gilberto Lourenço. "Interações farmacológicas envolvendo a glicoproteína-P: o caso particular
da digoxina". Mestrado, 2014. http://hdl.handle.net/10400.6/4876.
- Santos, João Pedro Ladeira; Alves, Gilberto Lourenço. "Inibição da glicoproteína-P: modelos celulares para ensaios de screening
in vitro". Mestrado, 2014. http://hdl.handle.net/10400.6/5142.
- Santos, Sara Catarina Gomes Coelho dos; Alves, Gilberto Lourenço. "Caracterização da utilização de medicamentos em idosos
residentes em lares através da aplicação dos critérios de Beers". Mestrado, 2014. http://hdl.handle.net/10400.6/5134.
- Alves, Gilberto Lourenço; Cardoso, Raquel Guilherme. "Avaliação do uso de medicamentos potencialmente inapropriados em idosos
institucionalizados em lares : aplicação dos Critérios de Beers". Mestrado, 2013. http://hdl.handle.net/10400.6/1632.
- Rodrigues, Márcio José de Abreu Marques; Falcão, Amílcar; Alves, Gilberto Lourenço. "Evaluation of the effect of herbal extracts
used in slimming regimens in the kinetic profile of narrow therapeutic range drugs used for cardiovascular pathologies: the
amiodarone". Doutoramento, 2013. http://hdl.handle.net/10316/24327.
- Martins, Ana Isabel Figueiredo; Alves, Gilberto Lourenço; Falcão, Amílcar. "Determinação fluorimétrica da rodamina 123 em
plasma de rato: ferramenta para a avaliação in vivo da actividade da glicoproteína-P". Mestrado, 2010. http://hdl.handle.net/10400.6/3948.
- Alves, Gilberto Lourenço; Falcão, Amílcar; Figueiredo, Isabel Vitória. "Caracterização farmacocinética do acetato de eslicarbazepina
e dos seus metabolitos S-licarbazepina e R-licarbazepina em murganhos". Doutoramento, 2008. http://hdl.handle.net/10316/5945.
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