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Chantal Fernandes is researcher at Centre for Neurosciences and Cell Biology (CNC), University of Coimbra and was invited as Assistant Professor like functions of the curricular unit of Medical Microbiology, Integrated Master's in Dentistry, Faculty of Medicine, University of Coimbra (FMUC) and keeps yearly teaching collaboration with the Master Course in Biomedical Research, FMUC since 2018. She graduated in Biochemistry at the Faculty of Sciences and Technology, Univ of Coimbra (FCTUC) in 2004 and completed a PhD Degree in Microbiology (FCTUC) in 2009. In 2010, Chantal Fernandes started her Postdoctoral research under the supervision of Teresa Gonçalves at the Medical Microbiology Research Group, at CNC, collaborating as a researcher in a FCT-funding project; soon after she obtained a post-doctoral FCT fellowship. Her post-doctoral project was centered in the study of the filamentous fungus Alternaria infectoria, evaluating the contribution of the modulatory plasticity of fungal cell wall components, chitin, ß-glucan and melanin, by compensatory mechanisms that strongly contribute for resistance against antifungals. The main achievements were obtained in collaboration with Neil Gow, expert in fungal pathogenesis (Univ of Exeter, UK) and Arturo Casadevall (Johns Hopkins Univ, USA), expert in immunity and fungal virulence, both recognized as world leading authorities in Medical Mycology. C Fernandes identified mutations leading to caspofungin resistance, by then the first of a novel group of antifungals, the echinocandins, to be introduced in human health. She determined the relative expression of genes involved in resistance mechanisms; identified 8 isoforms of chitin synthase in A. infectoria (deposited at NCBI databank), 2 of which holding Myosin Motor Domains, playing a crucial role in infection; she developed skills and optimized procedures of evaluation of the susceptibility of fungi to antifungals, such as the minimal inhibitory concentration, based on international standards (EUCAST and CLSI). She optimized protocols for the quantification of the major cell wall components chitin, glucan and melanin. She characterized the DHN-melanin produced by A. infectoria, and with that she become a specialist in Alternaria melanin and its impact in the relation with the infected host. In 2019, C Fernandes got a contract as Junior Researcher, by CNC. She contributed for the preparation of nanoparticles from fungal cell wall and demonstrated them as a tool to study the interaction of fungal cell wall components with phagocytic cells, and showed how the modification of cell wall components in A. infectoria modulate the host response. Lately, in a current collaboration with Jay Slater, FDA (Food and Drug Administration), she optimized the preparation of Alternaria allergens extracts and obtained extracts with higher abundance in protein and complexity and more IgE-reactivity than commercial allergen extracts. She also showed that Alternaria releases allergens by extracellular vesicles. She published a comprehensive revision about the mechanisms of Alternaria pathogenesis in a high impact factor journal. She is supervising 2 PhD students (2023.01320.BD; 2024.02373.BD), supervised/s 7 and co-supervised 4 Master’s degree students, and also undergraduate students, and was member of 8 evaluation panels of academic examinations. She published in 26 papers (9 as first, 3 as corresponding and 5 co-senior author) in indexed international journals, 1 book chapter as senior author, presented 6 oral and 18 posters communications, in national and international meetings, participated in 7 projects, and participates in ad hoc revision of manuscripts for 15 scientific journals.
Identificação

Identificação pessoal

Nome completo
Chantal Ana Vicência Fernandes

Nomes de citação

  • Fernandes, Chantal

Identificadores de autor

Ciência ID
EF1D-EE6A-2606
ORCID iD
0000-0001-7865-9946

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Micologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2009/07/24
Concluído
Biochemistry (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Osmotic and Thermal Adaptation in Ancient Thermophilic Bacteria: Biosynthesis of Glucosylglycerate and Mannosylglucosylglycerate " (TESE/DISSERTAÇÃO)
Distinção e Louvor
2004/06/18
Concluído
Biochemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
16
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2019/01/04 - Atual Investigador Contratado (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2010/06/01 - 2019/01/03 Postdoctoral fellowship in Medical Mycology Fundação para a Ciência e a Tecnologia, Portugal
2009 - 2010 Empresa de biotecnologia Crioestaminal, Portugal
2004/09/01 - 2008/12/01 Laboratory work as PhD student. Fundação para a Ciência e a Tecnologia, Portugal
Projetos

Bolsa

Designação Financiadores
2010 - 2019 Alternaria infectoria FKS, CHS and melanin synthesis genes: the perfect combination for opportunism
SFRH/BPD/63733/2009
Fundação para a Ciência e a Tecnologia, I.P.
2004 - 2008 Osmotic and Thermal Adaptation in Ancient Thermophilic Bacteria: Biosynthesis of Glucosylglycerate and Mannosylglucosylglycerate
SFRH / BD / 19599 / 2004
Fundação para a Ciência e a Tecnologia, I.P.

Projeto

Designação Financiadores
2022/07/01 - 2023/06/30 ActiveStent - Sustainable functionalization of stents to prevent urinary tract infections.
CENTRO-01-0145-FEDER-181221
Outra
Em curso
2022/06/08 - 2022/12/31 Antimicrobial action of natural extracts on the healthy skin microbiota.
022022
Co-Investigador Responsável (Co-IR)
Falcultad de Ciencias de la Slaud Universidad de Castilha-la Mancha
Concluído
2017/01/01 - 2020/12/31 Chronic allergic diseases and chronic inflammation originating from the gastrointestinal tract in the elderly
HEALTHY AGING 2020: CENTRO-01-0145-FEDER-000012
Outra
Concluído
2017 - 2017 Airways fungal colonization and respiratory allergies: Agents and Natural Prophylactic Approaches
FMUC & Santander-Totta
Outra
Concluído
2009 - 2011 Alternaria infectoria FKS, CHS and melanin synthesis genes: the combination for opportunism
PTDC/SAU-ESA/108636/2008
Outra
Fundação para a Ciência e a Tecnologia, Portugal
Concluído
2005 - 2008 Nature’s shieds to environmental stress. Biosynthesis of compatible solutes in extremely radiation-resistent Rubrobacter spp
POCI/BIA-MIC/56511/2004
Outra
Fundação para a Ciência e a Tecnologia
Concluído
2004 - 2006 Hotsolutes - New applications of compatible solutes from hyperthermophiles
COOP-CT-2003-508644
Outra
European Commission, Bélgica
Concluído
Produções

Publicações

Artigo em revista
  1. Daniela Antunes; Rita Domingues; Mariana Cruz-Almeida; Lisa Rodrigues; Olga Borges; Agostinho Carvalho; Arturo Casadevall; et al. "Cell wall nanoparticles from hyphae of Alternaria infectoria grown with caspofungin, nikkomycin, or pyroquilon trigger different activation profiles in macrophages". Microbiology Spectrum (2024): https://doi.org/10.1128/spectrum.00645-24.
    10.1128/spectrum.00645-24
  2. Diogo M. da Fonseca; Lisa Rodrigues; José Sousa-Baptista; Félix Marcos-Tejedor; Marta Mota; Rodrigo A. Cunha; Chantal Fernandes; Teresa Gonçalves. "Caffeine Protects Keratinocytes from Trichophyton mentagrophytes Infection and Behaves as an Antidermatophytic Agent". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms25158303.
    10.3390/ijms25158303
  3. Strader, Michael Brad; Saha, Aishwarya L.; Fernandes, Chantal; Sharma, Kavita; Hadiwinarta, Christian; Calheiros, Daniela; Conde-de-Oliveira, Gonçalo; Gonçalves, Teresa; Slater, Jay E.. "Distinct proteomes and allergen profiles appear across the life cycle stages of Alternaria alternata". Journal of Allergy and Clinical Immunology (2024): http://dx.doi.org/10.1016/j.jaci.2024.03.026.
    10.1016/j.jaci.2024.03.026
  4. Louisa Gomes; João Cotas; Fernandes, Chantal; Gonçalves, Teresa; Leonel Pereira. "Seaweed Calliblepharis jubata and Fucus vesiculosus Pigments: Anti-Dermatophytic Activity". Applied Sciences 14 4 (2024): 1456. https://doi.org/10.3390/app14041456.
    Acesso aberto • Publicado
  5. Michael Strader; Kavita Sharma; Aishwarya Saha; Chantal Fernandes; Goncalo Conde-de-Oliveira; Christian Hadiwinarta; Teresa Goncalves. "Distinct proteomes and allergen profiles appear across the life cycle stages of Alternaria alternata". Journal of Allergy and Clinical Immunology (2024): http://dx.doi.org/10.1016/j.jaci.2023.11.706.
    10.1016/j.jaci.2023.11.706
  6. Fernandes, Chantal; Sousa-Baptista, José; Lenha-Silva, Ana Filipa; Calheiros, Daniela; Correia, Edmilson; Figueirinha, Artur; Salgueiro, Lígia; Gonçalves, Teresa. "Azorean Black Tea (Camellia sinensis) Antidermatophytic and Fungicidal Properties". Molecules 28 23 (2023): 7775. http://dx.doi.org/10.3390/molecules28237775.
    Acesso aberto • 10.3390/molecules28237775
  7. Fernandes, Chantal; Casadevall, Arturo; Gonc¸alves, Teresa. "Mechanisms of Alternaria pathogenesis in animals and plants". FEMS Microbiology Reviews (2023): http://dx.doi.org/10.1093/femsre/fuad061.
    10.1093/femsre/fuad061
  8. Correia, Edmilson Emanuel Monteiro; Figueirinha, Artur; Rodrigues, Lisa; Pinela, José; Calhelha, Ricardo C.; Barros, Lillian; Fernandes, Chantal; Salgueiro, Lígia; Gonçalves, Teresa. "The Chemical Profile, and Antidermatophytic, Anti-Inflammatory, Antioxidant and Antitumor Activities of Withania chevalieri A.E. Gonç. Ethanolic Extract". Plants 12 13 (2023): 2502. http://dx.doi.org/10.3390/plants12132502.
    Acesso aberto • Publicado • 10.3390/plants12132502
  9. Strader, Michael; Saha, Aishwarya; Fernandes, Chantal; Hadiwinarta, Christian; Sharma, Kavita; Green, Brett; Lemons, Angela; Beezhold, Donald; Goncalves, Teresa. "Proteomic evaluation of spore and hyphae proteomes of Alternaria alternata". Journal of Allergy and Clinical Immunology 151 2 (2023): AB197. http://dx.doi.org/10.1016/j.jaci.2022.12.616.
    10.1016/j.jaci.2022.12.616
  10. Calheiros, Daniela; Dias, Maria Inês; Calhelha, Ricardo C.; Barros, Lillian; Ferreira, Isabel C. F. R.; Fernandes, Chantal; Gonçalves, Teresa. "Antifungal Activity of Spent Coffee Ground Extracts". Microorganisms 11 2 (2023): 242. http://dx.doi.org/10.3390/microorganisms11020242.
    10.3390/microorganisms11020242
  11. Gomes, Louisa; Monteiro, Pedro; Cotas, João; Gonçalves, Ana M. M.; Fernandes, Chantal; Gonçalves, Teresa; Pereira, Leonel. "Seaweeds’ pigments and phenolic compounds with antimicrobial potential". Biomolecular Concepts 13 1 (2022): 89-102. http://dx.doi.org/10.1515/bmc-2022-0003.
    10.1515/bmc-2022-0003
  12. Fernandes, Chantal; Mota, Marta; Barros, Lillian; Dias, Maria Inês; Ferreira, Isabel C. F. R.; Piedade, Ana P.; Casadevall, Arturo; Gonçalves, Teresa. "Pyomelanin Synthesis in Alternaria alternata Inhibits DHN-Melanin Synthesis and Decreases Cell Wall Chitin Content and Thickness". Frontiers in Microbiology 12 (2021): http://dx.doi.org/10.3389/fmicb.2021.691433.
    Acesso aberto • Publicado • 10.3389/fmicb.2021.691433
  13. Almeida, M. C.; Antunes, D.; Silva, B. M. A.; Rodrigues, L.; Mota, M.; Borges, O.; Fernandes, C.; Gonçalves, T.. "Early Interaction of Alternaria infectoria Conidia with Macrophages". Mycopathologia 184 3 (2019): 383-392. http://dx.doi.org/10.1007/s11046-019-00339-6.
    10.1007/s11046-019-00339-6
  14. Diogo, Patrícia; Mota, Marta; Fernandes, Chantal; Sequeira, Diana; Palma, Paulo; Caramelo, Francisco; Neves, M. Graça P.M.S.; et al. "Is the chlorophyll derivative Zn(II)e 6 Me a good photosensitizer to be used in root canal disinfection?". Photodiagnosis and Photodynamic Therapy 22 (2018): 205-211. http://dx.doi.org/10.1016/j.pdpdt.2018.04.009.
    10.1016/j.pdpdt.2018.04.009
  15. Paulo Silva; Chantal Fernandes; Lillian Barros; Isabel C. F. R. Ferreira; Leonel Pereira; Teresa Gonçalves. "The antifungal activity of extracts of Osmundea pinnatifida, an edible seaweed, indicates its usage as a safe environmental fungicide or as a food additive preventing post-harvest fungal food contamination". Food & Function 9 12 (2018): 6187-6195. https://doi.org/10.1039/C8FO01797B.
    10.1039/C8FO01797B
  16. Diogo, Patrícia; Fernandes, Chantal; Caramelo, Francisco; Mota, Marta; Miranda, Isabel M.; Faustino, M. A. F.; Neves, M. G. P. M. S.; et al. "Antimicrobial Photodynamic Therapy against Endodontic Enterococcus faecalis and Candida albicans Mono and Mixed Biofilms in the Presence of Photosensitizers: A Comparative Study with Classical Endodontic Irrigants". Frontiers in Microbiology 8 (2017): http://dx.doi.org/10.3389/fmicb.2017.00498.
    10.3389/fmicb.2017.00498
  17. Soares, Fabiana; Fernandes, Chantal; Silva, Paulo; Pereira, Leonel; Gonçalves, Teresa. "Antifungal activity of carrageenan extracts from the red alga Chondracanthus teedei var. lusitanicus". Journal of Applied Phycology 28 5 (2016): 2991-2998. http://dx.doi.org/10.1007/s10811-016-0849-9.
    10.1007/s10811-016-0849-9
  18. Fernandes, Chantal; Gow, Neil A.R.; Gonçalves, Teresa. "The importance of subclasses of chitin synthase enzymes with myosin-like domains for the fitness of fungi". Fungal Biology Reviews 30 1 (2016): 1-14. http://dx.doi.org/10.1016/j.fbr.2016.03.002.
    10.1016/j.fbr.2016.03.002
  19. Fernandes, Chantal; Prados-Rosales, Rafael; Silva, Branca M. A.; Nakouzi-Naranjo, Antonio; Zuzarte, Mónica; Chatterjee, Subhasish; Stark, Ruth E.; Casadevall, Arturo; Gonçalves, Teresa. "Activation of Melanin Synthesis in Alternaria infectoria by Antifungal Drugs". Antimicrobial Agents and Chemotherapy 60 3 (2015): 1646-1655. http://dx.doi.org/10.1128/aac.02190-15.
    10.1128/aac.02190-15
  20. Fernandes, C.; Anjos, J.; Walker, L. A.; Silva, B. M. A.; Cortes, L.; Mota, M.; Munro, C. A.; Gow, N. A. R.; Goncalves, T.. "Modulation of Alternaria infectoria Cell Wall Chitin and Glucan Synthesis by Cell Wall Synthase Inhibitors". Antimicrobial Agents and Chemotherapy 58 5 (2014): 2894-2904. http://dx.doi.org/10.1128/aac.02647-13.
    10.1128/aac.02647-13
  21. Anjos, Jorge; Fernandes, Chantal; Silva, Branca M. A.; Quintas, Célia; Abrunheiro, Alexandra; Gow, Neil A. R.; Gonçalves, Teresa. "ß(1,3)-glucan synthase complex fromAlternaria infectoria, a rare dematiaceous human pathogen". Medical Mycology 50 7 (2012): 716-725. http://dx.doi.org/10.3109/13693786.2012.675525.
    10.3109/13693786.2012.675525
  22. Fernandes, C.; Mendes, V.; Costa, J.; Empadinhas, N.; Jorge, C.; Lamosa, P.; Santos, H.; da Costa, M. S.. "Two Alternative Pathways for the Synthesis of the Rare Compatible Solute Mannosylglucosylglycerate in Petrotoga mobilis". Journal of Bacteriology 192 6 (2010): 1624-1633. http://dx.doi.org/10.1128/jb.01424-09.
    10.1128/jb.01424-09
  23. Nobre, A.; Alarico, S.; Fernandes, C.; Empadinhas, N.; da Costa, M. S.. "A Unique Combination of Genetic Systems for the Synthesis of Trehalose in Rubrobacter xylanophilus: Properties of a Rare Actinobacterial TreT". Journal of Bacteriology 190 24 (2008): 7939-7946. http://dx.doi.org/10.1128/jb.01055-08.
    10.1128/jb.01055-08
  24. Rodrigues, M. V.; Borges, N.; Henriques, M.; Lamosa, P.; Ventura, R.; Fernandes, C.; Empadinhas, N.; et al. "Bifunctional CTP:Inositol-1-Phosphate Cytidylyltransferase/CDP-Inositol:Inositol-1-Phosphate Transferase, the Key Enzyme for Di-myo-Inositol-Phosphate Synthesis in Several (Hyper)thermophiles". Journal of Bacteriology 189 15 (2007): 5405-5412. http://dx.doi.org/10.1128/jb.00465-07.
    10.1128/jb.00465-07
  25. Fernandes, C.; Empadinhas, N.; da Costa, M. S.. "Single-Step Pathway for Synthesis of Glucosylglycerate in Persephonella marina". Journal of Bacteriology 189 11 (2007): 4014-4019. http://dx.doi.org/10.1128/jb.00075-07.
    10.1128/jb.00075-07
  26. Fernandes, Chantal; Rainey, Fred A.; Fernanda Nobre, M.; Pinhal, Isabel; Folhas, Fátima; da Costa, Milton S.. "Herminiimonas fonticola gen. nov., sp. nov., a Betaproteobacterium isolated from a source of bottled mineral water". Systematic and Applied Microbiology 28 7 (2005): 596-603. http://dx.doi.org/10.1016/j.syapm.2005.03.013.
    10.1016/j.syapm.2005.03.013
Capítulo de livro
  1. Gonçalves, Teresa; Oliveira, Joana; Fernandes, Chantal. "Filamentous Fungi Extracellular Vesicles". In Current Topics in Microbiology and Immunology, 45-55. Springer International Publishing, 2021.
    10.1007/978-3-030-83391-6_5
Poster em conferência
  1. Daniela Calheiros; Rita Domingues; Mariana Afonso; Lisa Rodrigues; Célia Nogueira; Michael Brad Strader; Jay E. Slater; et al. "Characterization and immunomodulatory effect of Alternaria alternata extracellular vesicles". Trabalho apresentado em 4th meeting of the CIBB thematic area 'Innovative Therapies, 2024.
  2. Gonçalo Conde-de-Oliveira; Fernandes, Chantal; Luís Rodrigues; Rita Domingues; Daniela Calheiros; Michael Brad Strader; Aishwarya L. Saha; et al. Autor correspondente: Gonçalves, Teresa. "Seeking for fungal sialidase inhibitors". Trabalho apresentado em Microbiotec'23, 2023.
  3. José Sousa-Baptista; Ana Filipa Lenha-Silva; Rita Domingues; Daniela Calheiros; Edmilson Correia; Fernandes, Chantal; Gonçalves, Teresa. Autor correspondente: Gonçalves, Teresa. "Antidermatophytic activity of the Azorean black tea (Camellia sinensis)". Trabalho apresentado em Microbiotec’23, 2023.
  4. Daniela Calheiros; Maria Inês Dias; Ricardo C. Calhelha; Lillian Barros; Isabel C. F. R. Ferreira; Fernandes, Chantal; Gonçalves, Teresa. Autor correspondente: Gonçalves, Teresa. "Spent Coffee Grounds: a potential antifungal agent?". Trabalho apresentado em Microbiotec'23, 2023.
  5. Rita Domingues; Daniela Calheiros; Mariana Afonso; Lisa Rodrigues; Célia Nogueira; Michael Strader; Jay Slater; et al. "Characterization and immunomodulatory effect of Alternaria alternata extracellular vesicles.". Trabalho apresentado em 2nd Portuguese Network on Extracellular Vesicles, 2023.
  6. Rita Domingues; Mariana Afonso; Daniela Calheiros; Lisa Rodrigues; Célia Nogueira; Michael Strader; Jay Slater; et al. Autor correspondente: Teresa Gonçalves. "Characterization and Immunomodulatory effect of Alternaria alternata extracellular vesicles". Trabalho apresentado em 2ª REUNIÃO DA PORTUGUESE NETWORK ON EXTRACELLULAR VESICLES, 2023.
  7. Edmilson Correia, Lillian Barros, Chantal Fernandes, Teresa Gonçalves. "The in vitro Antidermatophytic activity of Withania chevalieri an endemic plant from Cape Verde". Trabalho apresentado em Microbiotec’21, 2021.
  8. Fernandes, Chantal; Daniela Antunes; Almeida, Mariana Cruz; Mónica Zuzarte; Olga Borges; Casadevall, Arturo; Teresa Gonçalves. "DHN-Melanin Synthesis Protects Alternaria infectoria from Antifungals and from Immune Response". Trabalho apresentado em World Microbe Forum 2021, ASM, FEMS, 2021.
  9. Fernandes, Chantal; Teresa Gonçalves. "Melanin Synthesis dual role in the Protection of Alternaria sp. against Antifungals and Immune Response". Trabalho apresentado em Microbiotec’19 Congress, 2019.
  10. Diogo, Patrícia; Mota, Marta; Fernandes, Chantal; Gonçalves, T.; Santos JM. "Eficácia antimicrobiana de irrigantes clássicos em biofilmes in vitro – 90s ou 30min de contacto?". Trabalho apresentado em Congresso da Sociedade Portuguesa de Endodontologia, Porto, 2018.
  11. Fernandes, Chantal; Gonçalves, Teresa. "Fungal melanin synthesis: a new target for antifungal agents". Trabalho apresentado em 1st Meeting on Biomedical Research @ UC, University of Coimbra, Coimbra, 2016.
  12. Fernandes, Chantal; Anjos, Jorge; Walker LA; B Silva; Cortes, L.; Mota, Marta; Munro, C. A.; Gow, Neil A.R.; Gonçalves, T.. "Modulation of cell wall chitin, glucan and melanin synthesis of Alternaria infectoria in response to cell wall synthases inhibitors". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, Coimbra, 2014.
  13. Fernandes, Chantal; Anjos, Jorge; Walker, L.; Prados-Rosales, Rafael; B Silva; Cortes, L.; Mota, Marta; et al. "Chitin, ß-glucan and melanin in Alternaria infectoria: the perfect combination for resistance to antifungals.". Trabalho apresentado em XII CNC Annual Meeting, Coimbra, 2014.
  14. Fernandes, Chantal; Anjos J; B Silva; Mota, Marta; Empadinhas, N.; Munro C; Walker, L.; et al. "Effect of cell wall synthases inhibitors in the modulation of cell wall chitin and glucan synthesis of Alternaria infectoria". Trabalho apresentado em XI CNC Annual Meeting, Biocant Park, Cantanhede, 2013.
  15. Fernandes, Chantal; Anjos, Jorge; Abrunheiro, Alexandra; Gonçalves, Teresa. "Effect of caspofungin and nikkomycin Z on the cell wall chitin and glucan synthesis in Alternaria infectoria". Trabalho apresentado em X CNC Annual Meeting, Biocant Park, Cantanhede, 2012.
  16. Fernandes, Chantal; Anjos, Jorge; Quintas, Célia; Abrunheiro, Alexandra; Gonçalves, Teresa. "Alternaria infectoria response to Caspofungin: modulation of ß(1,3)-glucan synthase and chitin synthases genes expression and cell wall components glucan and chitin.". Trabalho apresentado em IV FEBS Advanced Lecture Course Human Fungal Pathogens: Molecular Mechanisms of Host-Pathogen Interactions and Virulence, 2011.
  17. Nuno Empadinhas; Fernandes, Chantal; Mendes, V.; Costa, J.; Santos, H.; Costa MS. "Petrotoga mobilis possesses two pathways for the synthesis of the rare compatible solute mannosyl-a-1,2-glucosylglycerate". Trabalho apresentado em XVI National Congress of Biochemistry, 22-25th October, 2008, Ponta Delgada, Açores, Portugal, 2008.
  18. Fernandes, Chantal. "Glucosylglycerate: occurrence, biosynthesis and protein stabilization". Trabalho apresentado em V CNC Annual Meeting, Coimbra, 2007.
  19. Fernandes, Chantal; Empadinhas, N.; Costa MS. "The inositol-1-phosphate synthase from Rubrobacter xylanophilus". Trabalho apresentado em 2th FEMS Congress of European Microbiologists, Madrid, Spain, 2006.
Pré-impressão
  1. Louisa Gomes; João Cotas; Chantal Fernades; Teresa Gonçalves; Leonel Pereira. "Seaweeds Calliblepharis jubata and Fucus vesiculosus Pigments: Antidermatophytic Activity". 2023. https://doi.org/10.20944/preprints202310.0724.v1.
    10.20944/preprints202310.0724.v1
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2022/10/28 Unravelling Alternaria proteome to shed light on the fungal host-interaction 4th meeting of the CIBB thematic area 'Innovative Therapies
CIBB (Coimbra, Portugal)
2021/09/13 Characterization of filamentous fungi extracellular vesicles obtained using a novel protocol First Meeting of the Portuguese Network on Extracellular Vesicles (PNEV)
Portuguese Network on Extracellular Vesicles (Porto, Portugal)
2020/09/19 Melanin contribution to antimicrobial resistance 2nd CIBB INNOVATIVE THERAPIES RETREAT
(Coimbra, Portugal)
2016/12 Fungal melanin synthesis: a new target for antifungal agents 1st Meeting on Biomedical Research @ UC, University of Coimbra, Coimbra
(Portugal)
2011/12 Alternaria infectoria response to caspofungin: modulation of ß(1,3) - glucan synthase and chitin synthases genes expression and cell wall components glucan and chitin IX CNC Annual Meeting
Universidade de Coimbra
2007 Glucosylglycerate: occurrence, biosynthesis and protein stabilization V CNC Annual Meeting

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2023/09/01 - Atual Dissecting Alternaria alternata proteome towards novel tools to manage respiratory allergies
Coorientador de Daniela Calheiros
Doctoral Programme in Health Sciences (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2022/09 - 2023/09/29 Seeking for fungal syalidases inhibitors
Orientador de Gonçalo Conde de Oliveira
Master in Medicinal Chemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2023/05/08 - 2023/07/26 Antifungal activity of Margotia gummifera e Mentha cervina essential oils against Fusarium oxysporum
Orientador
Degree in Biotecnology (Licenciatura/Bacharelato)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2022/09/05 - 2023/06/27 Unraveling a Novel Sialidase in Allergy-Inducing Alternaria alternata fungus
Orientador de Luís Miguel Sousa Rodrigues
Integrated Master's degree in Medicine (Mestrado)
Universidade de Coimbra, Portugal
2021/09/01 - 2022/09/23 Isolation and characterization of seaweeds pigments and their anti fungal potential
Orientador de Louisa Ferreira Gomes
Master' s degree in Biodiversity and Vegetal Biotechnology (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021/09/01 - 2022/09/14 Azorean Black Tea: in vitro antidermatophytic activity and influence on the human toe microbiota
Orientador de Ana Filipa Lenha Martins da Silva
Master’s Degree in Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/09/01 - 2021/11/18 Optimization of the recovery of extracellular vesicles from filamentous fungi
Orientador de Rita Sofia de Jesus Pita Domingues
Master’s Degree in Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/07 - 2020/12/11 Interaction of filamentous fungi extracellular vesicles with respiratory tract epithelium
Orientador de Joana Mafalda Coelho Oliveira
Master’s Degree in Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/05/02 - 2019/07/24 Role of extracellular vesicles of filamentous fungi in fungal disease
Orientador de Rita Sofia de Jesus Pita Domingues
Degree in Biotechnology (Licenciatura/Bacharelato)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2016/03 - 2016/07 Study of the melanization of Candida sp. and its effect on the resistance against antifungals
Orientador de Anastasia Barone
Corso di Laurea Magistrale in Biologia (Licenciatura/Bacharelato)
Università degli Studi del Sannio Dipartimento di Scienze e Tecnologie, Itália
2015/09 - 2016/07 Immunomodulatory effect of different components of the cell wall of Alternaria spp.
Coorientador de Daniela Antunes
Master’s Degree in Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014/09 - 2015/07 Antifungal activity of Carrageenan extracts from the red alga Chondracanthus teed var. lusitanicus
Coorientador de Fabiana Soares
Master's degree in Biodiversity and Vegetal Biotechnology (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014/03 - 2015/06 Screening of biotechnological potential of Osmundea pinnatifida: cultivation trials and biological activities
Coorientador de Paulo Jorges Ferreira da Silva
Master's degree in Biodiversity and Vegetal Biotechnology (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2024/09/15 - 2024/09/15 Science Communication Activities: Participation in the organization of the International Microorganism Day 2024, Exploratório Centro Ciência Viva de Coimbra, Portugal. https://www.uc.pt/cultura/uc-exploratorio/apresentacao-de-livros/dia-internacional-do-microrganismo/ (2024/09/15 - 2024/09/15)
Exposição (Coorganizador)
Universidade de Coimbra, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2023/09/17 - 2023/09/17 Science Communication Activities: Participation in the organization of the International Microorganism Day 2023, Exploratório Centro Ciência Viva de Coimbra, Portugal. https://noticias.uc.pt/artigos/universidade-de-coimbra-celebra-dia-internacional-do-microrganismo/
Exposição
International Microorganism Day 2023
Universidade de Coimbra, Portugal
2023/06/22 - 2023/06/23 6th ECMM Educational Symposium - The Fungal Exposome and Health Issues
Simpósio
6th ECMM Educational Symposium - The Fungal Exposome and Health Issues
European Confederation of Medical Mycology, Suiça
2022/09/17 - 2022/09/17 Science Communication Activities: Participation in the organization of the International Microorganism Day 2022, RUC, Radio Universitário de Coimbra, Coimbra, Portugal. https://www.uc.pt/fctuc/dcv/noticias/o-dia-internacional-do-microrganismo-este-ano-vai-a-radio/
Outro
International Microorganism Day 2023
Universidade de Coimbra, Portugal
2021/09/17 - 2021/09/17 Science Communication Activities: Participation in the organization MicroScience Photo Galery: ¿Microrganismos de estimação¿, under the scope of the International Microorganism Day 2021 at the Exploratório - Ciência Viva, Coimbra, Portugal. https://noticias.uc.pt/artigos/dia-internacional-do-microrganismo-assinalado-com-a-exposicao-microrganismos-de-estimacao/
Exposição
International Microorganism Day 2021
2020/12/18 - 2020/12/18 First Workshop of the Portuguese Network on Extracellular Vesicles
Oficina (workshop)
First Workshop of the Portuguese Network on Extracellular Vesicles: EVs in Health and Disease
2020/09/17 - 2020/10/05 Science Communication Activities: Participation in the organization MicroScience Photo Galery: ¿Microrganismos de estimação¿, under the scope of the International Microorganism Day 2020 at the Exploratório - Ciência Viva, Coimbra, Portugal. https://www.campeaoprovincias.pt/noticia/uc-participa-nas-comemoracoes-do-dia-internacional-do-microrganismo
Exposição
International Microorganism Day 2020
Universidade de Coimbra, Portugal
2017/03 - 2017/03 Participation in the organization of the Workshop “Fungo com melanina: proteção contra o ambiente” for the students of Colégio Rainha Santa, Mar 2017
Oficina (workshop)
2008/11/22 - 2008/11/23 Participation in the organization of the Fórum Ciência Viva, Lisboa, Nov 2008
Exposição
Fórum Ciência Viva, 2008

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2023/09/29 Seeking for fungal sialidase inhibitors
Orientador
Gonçalo Conde de Oliveira (Mestrado)
Universidade de Coimbra, Portugal
2023/06/27 Unraveling a Novel Sialidase in Allergy-Inducing Alternaria alternata fungus
Orientador
Luís Miguel Sousa Rodrigues (Mestrado)
Universidade de Coimbra, Portugal
2022/09/23 Isolation and characterization of seaweeds pigments and their anti fungal potential
Orientador
Louisa Ferreira Gomes (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022/09/14 Azorean Black Tea: in vitro antidermatophytic activity and influence on the human toe microbiota
Orientador
Ana Filipa Lenha Martins da Silva (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021/11/18 Optimization of the recovery of extracellular vesicles from filamentous fungi
Orientador
Rita Sofia de Jesus Pita Domingues (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/12/11 Interaction of filamentos fungi extracellular vesicles with respiratory tract epithelium
Orientador
Joana Mafalda Coelho Oliveira (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/07/25 O papel das vesículas extracelulares de fungos filamentosos na doença fúngica
Orientador
Rita Sofia de Jesus Pita Domingues (Outro)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2015/09 Caracterização do perfil biotecnológico de Dilsea carnosa. Ensaios de cultivo em IMTA, Análise do conteúdo coloidal, Quantificação de potencial bioativo
Arguente principal
João Filipe Nogueira Marques (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2024/02/05 - Atual Invited assistant professor - Practical classes of the curricular unit of Medical Microbiology, Integrated Master's in Dentistry, FMUC Integrated Master's in Dentistry (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2023/11/17 - 2033/11/17 Infection and Immunity - Master in Biomedical Research, UC. Master in Biomedical Research, UC. Universidade de Coimbra Faculdade de Medicina, Portugal
2022/11 - 2022/11 Infection and Immunity - Master in Biomedical Research, UC. Master in Biomedical Research, UC. Universidade de Coimbra Faculdade de Medicina, Portugal
2021/11 - 2021/11 Infection and Immunity - Master in Biomedical Research, UC. Master in Biomedical Research, UC. Universidade de Coimbra Faculdade de Medicina, Portugal
2020/11 - 2020/11 Infection and Immunity - Master in Biomedical Research, UC. Master in Biomedical Research, UC. (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2019/11 - 2019/11 Infection and Immunity - Master in Biomedical Research, UC. Master in Biomedical Research, UC. Universidade de Coimbra Faculdade de Medicina, Portugal
2018/11 - 2018/11 Infection and Immunity - Master in Biomedical Research, UC. Master in Biomedical Research, UC. (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal

Revisão ad hoc de artigos em revista

Nome da revista (ISSN) Editora
2024/09/30 - Atual Applied Biosciences (2813-0464) MDPI
2024/07/22 - Atual International Journal of Molecular Sciences (1422-0067) mdpi
2024/06/25 - Atual Microbiology Research (2036-7481) MDPI AG
2024/05/13 - Atual Antibiotics (2079-6382) MDPI
2024/04/26 - Atual Metabolites (2218-1989) MDPI AG
2024/04/15 - Atual Pharmaceutics (1999-4923) MDPI AG
2024/03/23 - Atual Agriculture (2077-0472) MDPI
2023/10/30 - Atual Biomolecules (2218-273X) MDPI AG
2023/09/27 - Atual Journal of Fungi (2309-608X) MDPI
2023/09/12 - Atual Microorganisms (20762607) MDPI AG
2023/05/15 - Atual Foods (23048158) MDPI
2023/06/30 - 2023/07/19 BMC Microbiology (14712180) BioMed Central Ltd
2022/10/26 - 2023/01/19 Medical Mycology Oxford Academic
2018/05 - 2018/10 Journal of Oceanology and Limnology Springer
2017/02 - 2017/04 Journal of Agricultural and Food Chemistry American Chemical Society
Distinções

Prémio

2018 Best Presentation at the 6th Central European Summer Course on Mycology and 3rd Rising Stars in Mycology Workshop (July 2018), Szeged, Hungary. Presented by Daniela Antunes
2018 Best Poster Eficácia antimicrobiana de irrigantes clássicos em biofilmes in vitro – 90s ou 30min de contacto? Diogo P, Mota M, Fernandes C, Gonçalves T, Santos JM
I Congresso da Sociedade Portuguesa de Endodontologia, Portugal
2018 Best oral communication at the XXVII Reunião de Medicina Dentária e Estomatologia de Coimbra, Faculty of Medicine, University of Coimbra. Presented by Patrícia Diogo