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Identificação

Identificação pessoal

Nome completo
Maria Ângela Cabral Garcia Taipa Meneses de Oliveira

Nomes de citação

  • M. Ângela Taipa
  • Taipa, M.A.
  • Taipa, M. Ângela
  • Taipa, M.Â.

Identificadores de autor

Ciência ID
F010-C326-AC10
ORCID iD
0000-0003-3776-180X
Google Scholar ID
https://scholar.google.pt/citations?user=jPFkCSkAAAAJ&hl=en

Endereços de correio eletrónico

  • angela.taipa@tecnico.ulisboa.pt (Profissional)

Telefones

Fax
  • 218419062 (Profissional)
Telefone
  • 218419065 (Profissional)

Moradas

  • Institute for Bioengineering and Biosciences. Instituto Superior Técnico, Av. Rovisco Pais, 1049-001, Lisboa, Lisboa, Portugal (Profissional)

Websites

Formação
Grau Classificação
1997
Concluído
 Biotecnologia (Doutoramento)
Especialização em Biotecnologia
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Purification and Characterization of Chromobacterium viscosum lipase: Its Homology with the Lipase from Pseudomonas glumae" (TESE/DISSERTAÇÃO)
 Distinção e Louvor
1994
Concluído
 Public Proofs for Pedagogical Aptitude and Scientific Ability (equivalence to M.Sc) (Mestrado)
Especialização em Biotecnologia
Universidade de Lisboa Instituto Superior Técnico, Portugal
 Distinção e Louvor
1989
Concluído
 Engenharia Química (Biotecnologia) (Licenciatura)
Especialização em Biotecnologia
Universidade de Lisboa Instituto Superior Técnico, Portugal
 15 Valores
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
1997/05/05 - Atual Professor Auxiliar (Docente Universitário) Universidade de Lisboa Instituto Superior Técnico, Portugal
1992/01/01 - 1997/05/04 Assistente (Docente Universitário) Universidade de Lisboa Instituto Superior Técnico, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
1991/01/01 - 1991/12/31 PhD Student (PhD Fellowship /Programa Ciência) Universidade de Lisboa Instituto Superior Técnico, Portugal
1989/01/01 - 1990/12/31 Research Assistant (Animal Cell Culture; Production of Monoclonal Antibodies) -Fellowship JNICT/FSE Laboratório de Virologia, Instituto Gulbenkian de Ciência, Oeiras, Lisboa, Portugal
1990/01/01 - 1990/03/31 Training period, (Immunotechnology) Gesellshaft für Biotechnologishe Forchung, Braunschweig, German : Gesellshaft für Biotechnologishe Forchung, Braunschweig, Germany, Alemanha
Projetos

Projeto

Designação Financiadores
2021/01/01 - 2025/12/31 Institute for Health and Bioeconomy
LA/P/0140/2020
10.54499/LA/P/0140/2020
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade Nova de Lisboa, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2022/01/01 - 2023/12/31 ChiCoBionts - Harnessing the catalyst power of host-microbe interactions: a quest for novel chitinases from octocoral symbionts
EXPL/BIA-MIC/0286/2021
Co-Investigador Responsável (Co-IR)
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2019/01/01 - 2019/12/31 Institute for Bioengineering and Biosciences
UID/BIO/04565/2019
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2011/01/01 - 2012/12/31 Projecto Estratégico - LA 23 - 2011-2012
PEst-OE/EQB/LA0023/2011
Instituto de Biotecnologia e Bioengenharia, Portugal

Universidade do Algarve, Portugal

Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade do Minho, Portugal

Fundação Gaspar Frutuoso, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade dos Açores, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2007/08/10 - 2011/05/09 Biomimetic Affinity Polymer Systems for Molecular Recognition of Antibodies
3599-PPCDT/64822/PT
Investigador responsável
Instituto de Biotecnologia e Bioengenharia, Portugal

Universidade de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2004/01/15 - 2008/01/15 Design of Stabilizing Affinity Molecular Probes : A Rational Approach to Assess and Enhance Protein Stability
POCI/45296/PT
Investigador responsável
Instituto de Biotecnologia e Bioengenharia, Portugal

Universidade de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2001/01/15 - 2004/01/15 Purification of immunologlobulin subclasses by innovative affinity methodologies based on biomimetic ligands.
POCI/36199/PT
Investigador responsável
Instituto de Biotecnologia e Bioengenharia, Portugal

Universidade de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2000/10/01 - 2002/09/30 Bioartificial pancreas: Preliminary studies of hemocompatibility, diffusion and immunoisolation
PRAXIS/P/BIO/12007/1998
Investigador
Instituto de Biotecnologia e Bioengenharia, Portugal

Universidade de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Taipa, M. Ângela; Professor Joaquim Manuel Sampaio Cabral; Helena Santos. "Application of 31-P NMR to compare the metabolism of free and gel entrapped yeast cells". Trabalho apresentado em Physiology of Immobilized Cells, 1990.
Artigo em revista
  1. Ferreira-Faria, Diogo; Taipa, M. Ângela. "Thermal Stabilization of Lipases Bound to Solid-Phase Triazine-Scaffolded Biomimetic Ligands: A Preliminary Assessment". Processes 12 2 (2024): 371. http://dx.doi.org/10.3390/pr12020371.
    10.3390/pr12020371
  2. Luis P. Fonseca; M. Ângela Taipa. "One-Step Purification of Recombinant Cutinase from an E. coli Extract Using a Stabilizing Triazine-Scaffolded Synthetic Affinity Ligand". Biomimetics 9 1 (2024): 57. https://www.mdpi.com/2313-7673/9/1/57.
    Acesso aberto • 10.3390/biomimetics9010057
  3. da Silva, Daniela M. G.; Pedrosa, Filipa R.; Ângela Taipa, M.; Costa, Rodrigo; Keller-Costa, Tina. "Widespread occurrence of chitinase-encoding genes suggests the Endozoicomonadaceae family as a key player in chitin processing in the marine benthos". ISME Communications 3 1 (2023): http://dx.doi.org/10.1038/s43705-023-00316-7.
    10.1038/s43705-023-00316-7
  4. Taipa, M. Ângela; Azevedo, Ana M.; Grilo, António L.; Couto, Pedro T.; Ferreira, Filipe A. G.; Fortuna, Ana R. M.; Pinto, Inês F.; Santos, Rafael M.; Santos, Susana B.. "Student Collaboration in a Series of Integrated Experiments To Study Enzyme Reactor Modeling with Immobilized Cell-Based Invertase". Journal of Chemical Education 92 7 (2015): 1238-1243. http://dx.doi.org/10.1021/ed500842p.
    Publicado • 10.1021/ed500842p
  5. Taipa, M. Ângela. "Immunological Assays: Biotools for High Throughput Screening and Characterisation of Combinatorial Libraries". Advances in Combinatorial Chemistry & High Throughput Screening 1 (2013): 130-158.
  6. Silva, C.S.O.; Lansalot, M.; Garcia, J.Q.; Taipa, M.T.; Martinho, J.M.G.. "Synthesis and characterization of biomimetic nanogels for immunorecognition". Colloids and Surfaces B: Biointerfaces 112 (2013): 264-271. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883438914&partnerID=MN8TOARS.
    Publicado • 10.1016/j.colsurfb.2013.08.003
  7. Sousa, I.T.; Lourenço, N.M.T.; Afonso, C.A.M.; Taipa, M.A.. "Protein stabilization with a dipeptide-mimic triazine-scaffolded synthetic affinity ligand". Journal of Molecular Recognition 26 2 (2013): 104-112. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872736687&partnerID=MN8TOARS.
    Publicado • 10.1002/jmr.2252
  8. Soysa, I.T.; Ruiu, L.; Lowe, C.R.; Taipa, M.A.. "Synthetic affinity ligands as a novel tool to improve protein stability". Journal of Molecular Recognition 22 2 (2009): 83-90. http://www.scopus.com/inward/record.url?eid=2-s2.0-63849220136&partnerID=MN8TOARS.
    10.1002/jmr.900
  9. Taipa, M.Â.. "Immunoassays: Biological tools for high throughput screening and characterisation of combinatorial libraries". Combinatorial Chemistry and High Throughput Screening 11 4 (2008): 325-335. http://www.scopus.com/inward/record.url?eid=2-s2.0-44249114861&partnerID=MN8TOARS.
    Publicado • 10.2174/138620708784246031
  10. Santos, A.M.; Fedorov, A.; Martinho, J.M.G.; Baptista, R.P.; Taipa, M.A.; Cabral, J.M.S.. "Orientation of cutinase adsorbed onto PMMA nanoparticles probed by tryptophan fluorescence". Journal of Physical Chemistry B 112 12 (2008): 3581-3585. http://www.scopus.com/inward/record.url?eid=2-s2.0-43049181786&partnerID=MN8TOARS.
    10.1021/jp711903e
  11. Roque, A.C.A.; Silva, C.S.O.; Taipa, M.A.. "Affinity-based methodologies and ligands for antibody purification: Advances and perspectives". Journal of Chromatography A 1160 1-2 (2007): 44-55. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447527576&partnerID=MN8TOARS.
    10.1016/j.chroma.2007.05.109
  12. Silva, C.S.O.; Baptista, R.P.; Santos, A.M.; Martinho, J.M.G.; Cabral, J.M.S.; Taipa, M.Â.. "Adsorption of human IgG on to poly(N-isopropylacrylamide)-based polymer particles". Biotechnology Letters 28 24 (2006): 2019-2025. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845297264&partnerID=MN8TOARS.
    10.1007/s10529-006-9188-2
  13. Ruiu, L.; Roque, A.C.A.; Taipa, M.A.; Lowe, C.R.. "De novo design, synthesis and screening of a combinatorial library of complementary ligands directed towards the surface of cutinase from Fusarium solani pisi". Journal of Molecular Recognition 19 4 (2006): 372-378. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747255085&partnerID=MN8TOARS.
    10.1002/jmr.782
  14. Roque, A.C.A.; Taipa, M.Â.; Lowe, C.R.. "Synthesis and screening of a rationally designed combinatorial library of affinity ligands mimicking protein L from Peptostreptococcus magnus". Journal of Molecular Recognition 18 3 (2005): 213-224. http://www.scopus.com/inward/record.url?eid=2-s2.0-18944395451&partnerID=MN8TOARS.
    10.1002/jmr.733
  15. Roque, A.C.A.; Taipa, M.Â.; Lowe, C.R.. "An artificial protein L for the purification of immunoglobulins and Fab fragments by affinity chromatography". Journal of Chromatography A 1064 2 (2005): 157-167. http://www.scopus.com/inward/record.url?eid=2-s2.0-12344291384&partnerID=MN8TOARS.
    10.1016/j.chroma.2004.11.102
  16. Roque, A.C.A.; Lowe, C.R.; Taipa, M.Â.. "Antibodies and genetically engineered related molecules: Production and purification". Biotechnology Progress 20 3 (2004): 639-654. http://www.scopus.com/inward/record.url?eid=2-s2.0-2942722679&partnerID=MN8TOARS.
    10.1021/bp030070k
  17. Roque, A.C.A.; Taipa, M.A.; Lowe, C.R.. "A new method for the screening of solid-phase combinatorial libraries for affinity chromatography". Journal of Molecular Recognition 17 3 (2004): 262-267. http://www.scopus.com/inward/record.url?eid=2-s2.0-2542457776&partnerID=MN8TOARS.
    10.1002/jmr.661
  18. Mergulhão, F.J.M.; Taipa, M.A.; Cabral, J.M.S.; Monteiro, G.A.. "Evaluation of bottlenecks in proinsulin secretion by Escherichia coli". Journal of Biotechnology 109 1-2 (2004): 31-43. http://www.scopus.com/inward/record.url?eid=2-s2.0-1842425886&partnerID=MN8TOARS.
    10.1016/j.jbiotec.2003.10.024
  19. Mergulhão, F.J.M.; Monteiro, G.A.; Cabral, J.M.S.; Taipa, M.A.. "Design of bacterial vector systems for the production of recombinant proteins in Escherichia coli". Journal of Microbiology and Biotechnology 14 1 (2004): 1-14. http://www.scopus.com/inward/record.url?eid=2-s2.0-1542285371&partnerID=MN8TOARS.
  20. Mergulhão, F.J.M.; Monteiro, G.A.; Larsson, G.; Bostrom, M.; Farewell, A.; Nyström, T.; Cabral, J.M.S.; Taipa, M.A.. "Evaluation of inducible promoters on the secretion of a ZZ-proinsulin fusion protein in Escherichia coli". Biotechnology and Applied Biochemistry 38 1 (2003): 87-93. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042591085&partnerID=MN8TOARS.
    10.1042/BA20030043
  21. Leirião, P.R.S.; Fonseca, L.J.P.; Taipa, M.A.; Cabral, J.M.S.; Mateus, M.. "Horseradish peroxidase immobilized through its carboxylic groups onto a polyacrylonitrile membrane: Comparison of enzyme performances with inorganic beaded supports". Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology 110 1 (2003): 1-10. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042166222&partnerID=MN8TOARS.
    10.1385/ABAB:110:1:1
  22. Martinho, J.M.G.; Santos, A.M.; Fedorov, A.; Baptista, R.P.; Taipa, M.A.; Cabral, J.M.S.. "Fluorescence of the Single Tryptophan of Cutinase: Temperature and pH Effect on Protein Conformation and Dynamics". Photochemistry and Photobiology 78 1 (2003): 15-22. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242365531&partnerID=MN8TOARS.
    10.1562/0031-8655(2003)078<0015:FOTSTO>2.0.CO;2
  23. Mergulhão, F.J.M.; Monteiro, G.A.; Larsson, G.; Sandén, A.M.; Farewell, A.; Nystrom, T.; Cabral, J.M.S.; Taipa, M.A.. "Medium and copy number effects on the secretion of human proinsulin in Escherichia coli using the universal stress promoters uspA and uspB". Applied Microbiology and Biotechnology 61 5-6 (2003): 495-501. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037899027&partnerID=MN8TOARS.
  24. Baptista, R.P.; Santos, A.M.; Fedorov, A.; Martinho, J.M.G.; Pichot, C.; Elaïssari, A.; Cabral, J.M.S.; Taipa, M.A.. "Activity, conformation and dynamics of cutinase adsorbed on poly(methyl methacrylate) latex particles". Journal of Biotechnology 102 3 (2003): 241-249. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037688019&partnerID=MN8TOARS.
    10.1016/S0168-1656(03)00033-6
  25. Calado, C.R.C.; Taipa, M.A.; Cabral, J.M.S.; Fonseca, L.P.. "Optimisation of culture conditions and characterisation of cutinase produced by recombinant Saccharomyces cerevisiae". Enzyme and Microbial Technology 31 1-2 (2002): 161-170. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036644010&partnerID=MN8TOARS.
    10.1016/S0141-0229(02)00084-4
  26. Rodrigues, Á.R.; Cabral, J.M.S.; Taipa, M.Â.. "Immobilization of Chromobacterium viscosum lipase on Eudragit S-100: Coupling, characterization and kinetic application in organic and biphasic media". Enzyme and Microbial Technology 31 1-2 (2002): 133-141. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036643977&partnerID=MN8TOARS.
    10.1016/S0141-0229(02)00087-X
  27. Mergulhão, F.J.M.; Monteiro, G.A.; Cabral, J.M.S.; Taipa, M.A.. "A quantitative ELISA for monitoring the secretion of ZZ-fusion proteins using SpA domain as immunodetection reporter system". Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology 19 3 (2001): 239-244. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035168991&partnerID=MN8TOARS.
    10.1385/MB:19:3:239
  28. Taipa, M.Â.; Kaul, R.-H.; Mattiasson, B.; Cabrai, J.M.S.. "Recovery of a monoclonal antibody from hybridoma culture supernatant by affinity precipitation with Eudragit S-100". Bioseparation 9 5 (2000): 291-298. http://www.scopus.com/inward/record.url?eid=2-s2.0-0009506003&partnerID=MN8TOARS.
    10.1023/A:1011183904966
  29. Melo, E.P.; Taipa, M.A.; Castellar, M.R.; Costa, S.M.B.; Cabral, J.M.S.. "A spectroscopic analysis of thermal stability of the Chromobacterium viscosum lipase". Biophysical Chemistry 87 2-3 (2000): 111-120. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034735624&partnerID=MN8TOARS.
    10.1016/S0301-4622(00)00171-X
  30. Mergulhao, F.J.M.; Monteiro, G.A.; Kelly, A.G.; Taipa, M.A.; Joaquim, M.S.C.. "Recombinant human proinsulin: A new approach in gene assembly and protein expression". Journal of Microbiology and Biotechnology 10 5 (2000): 690-693. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033757725&partnerID=MN8TOARS.
  31. Krieger, N.; Taipa, M.A.; Melo, E.H.M.; Lima-Filho, J.L.; Aires-Barros, M.R.; Cabral, J.M.S.. "Purification of a Penicillium citrinum lipase by chromatographic processes". Bioprocess Engineering 20 1 (1999): 59-65. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033003342&partnerID=MN8TOARS.
    10.1007/s004490050560
  32. Mergulhão, F.J.M.; Kelly, A.G.; Monteiro, G.A.; Taipa, M.A.; Cabral, J.M.S.. "Troubleshooting in gene splicing by overlap extension: A step-wise method". Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology 12 3 (1999): 285-287. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033428016&partnerID=MN8TOARS.
  33. Taipa, M.A.; Kaul, R.; Mattiasson, B.; Cabral, J.M.S.. "Preliminary studies on the purification of a monoclonal antibody by affinity precipitation with Eudragit S-100". Journal of Molecular Recognition 11 1-6 (1998): 240-242. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032457255&partnerID=MN8TOARS.
  34. Krieger, N.; Taipa, M.A.; Melo, E.H.M.; Lima-Filho, J.L.; Aires-Barros, M.R.; Cabral, J.M.S.. "Kinetic Characterization of Penicillium citrinum Lipase in AOT/Isooctane-Reversed Micelles". Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology 67 1-2 (1997): 87-95. http://www.scopus.com/inward/record.url?eid=2-s2.0-1842817562&partnerID=MN8TOARS.
    10.1007/BF02787844
  35. Krieger, N.; Taipa, M.A.; Aires-Barros, M.R.; Melo, E.H.M.; Lima-Filho, J.L.; Cabral, J.M.S.. "Purification of the Penicillium citrinum lipase using AOT reversed micelles". Journal of Chemical Technology and Biotechnology 69 1 (1997): 77-85. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031148956&partnerID=MN8TOARS.
    10.1002/(SICI)1097-4660(199705)69:1<77::AID-JCTB666>3.0.CO;2-V
  36. Castellar, M.R.; Taipa, M.A.; Cabral, J.M.S.. "Kinetic and stability characterization of Chromobacterium viscosum lipase and its comparison with Pseudomonas glumae lipase". Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology 61 3 (1996): 299-314. http://www.scopus.com/inward/record.url?eid=2-s2.0-0000115897&partnerID=MN8TOARS.
  37. Taipa, M.A.; Liebeton, K.. "Lipase from Chromobacterium viscosum: Biochemical characterization indicating homology to the lipase from Pseudomonas glumae". Biochimica et Biophysica Acta - Lipids and Lipid Metabolism 1256 3 (1995): 396-402. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029032855&partnerID=MN8TOARS.
    10.1016/0005-2760(95)00052-E
  38. Taipa, M.A.; Moura-Pinto, P.; Cabral, J.M.S.. "Identification and characterization of Chromobacterium viscosum lipase". Biotechnology Techniques 8 1 (1994): 27-32. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027951269&partnerID=MN8TOARS.
    10.1007/BF00207629
  39. Taipa, M.A.; Cabral, J.M.S.; Santos, H.. "Comparison of glucose fermentation by suspended and gel-entrapped yeast cells: An in vivo nuclear magnetic resonance study". Biotechnology and Bioengineering 41 6 (1993): 647-653. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027572086&partnerID=MN8TOARS.
  40. Taipa, M.A.; Aires-Barros, M.R.; Cabral, J.M.S.. "Purification of lipases". Journal of Biotechnology 26 2-3 (1992): 111-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026677176&partnerID=MN8TOARS.
    10.1016/0168-1656(92)90001-P
  41. Taipa, M.A.; Aires-Barros, M.R.; Cabral, J.M.S.. "Purification of lipases from Chromobacterium viscosum: Is there a high molecular weight lipase?". Biotechnology Techniques 6 6 (1992): 533-538. http://www.scopus.com/inward/record.url?eid=2-s2.0-51249162969&partnerID=MN8TOARS.
    10.1007/BF02447827
Capítulo de livro
  1. Sousa, Isabel T.; Taipa, M. Ângela. "Biomimetic Affinity Ligands for Protein Purification". In Protein Downstream Processing, 167-199. Springer US, 2020.
    10.1007/978-1-0716-0775-6_14
  2. Taipa, M. Ângela; Fernandes, Pedro; de Carvalho, Carla C. C. R.. "Production and Purification of Therapeutic Enzymes". In Therapeutic Enzymes: Function and Clinical Implications, 1-24. Springer Singapore, 2019.
    10.1007/978-981-13-7709-9_1
  3. Ângela Taipa, M. "AFFINITY SEPARATION | Rational Design, Synthesis, and Evaluation: Affinity Ligands". In Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. Elsevier, 2014.
    10.1016/b978-0-12-409547-2.10738-3
  4. Sousa, Isabel T.; Taipa, M. Ângela. "Biomimetic Affinity Ligands for Protein Purification". In Protein Downstream Processing, 231-262. Humana Press, 2014.
    10.1007/978-1-62703-977-2_20
  5. M. Ângela Taipa; Miguel Gama. "Estrutura e Função de Enzimas". In Engenharia Enzimática. LIDEL, 2003.
  6. Maria Raquel Aires-Barros; M. Ângela Taipa; Joaquim M.S. Cabral. "Isolation and purification of lipases". In Lipases - Their Biochemistry, Structure and Analysis. Springer New York, 1992.
Tese / Dissertação
  1. Taipa, M. Ângela. "Purification and Characterization of Chromobacterium viscosum lipase: Its Homology with the Lipase from Pseudomonas glumae". Doutoramento, Universidade de Lisboa Instituto Superior Técnico, 1997.

Propriedade Intelectual

Patente
  1. Christopher R Lowe; Ana Cecília Afonso Roque; Taipa, M. Ângela. 2003. "Affinity adsorbents for immunoglobulins". Reino Unido.
    Expirada
Atividades

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2024/02 - Atual Harnessing New Chitinases from Uncultured Coral Symbionts for Potential Blue Biotech Applications
Orientador de Filipa Rodrigues Pedrosa
 Biological Engineering (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2024/02 - Atual Insights towards protein stabilization: Modeling interactions and synthesis of triazine-scaffolded synthetic affinity ligands
Orientador de Afonso José Da Costa e Ervideira Coalho
Chemistry (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2024/02 - Atual Peroxygenase-catalysed oxyfunctionalisation reactions
Coorientador de Rodrigo de Matos de Fernandes Manso
 Biological Engineering (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2023/02 - 2023/07 Production and characterization of new recombinant chitinases from uncultured coral bacterial symbionts
Orientador
 Bachelor in Biological Engineering, 1rst Cycle Integrated Project (Outra) (Outra)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/03 - 2023/07 Chitin degradation pathways in bacterial symbionts of marine animals
Coorientador de Daniela Marina Gonçalves da Silva e Filipa Rodrigues Pedrosa
 Bachelor in Biological Engineering, 1rst Cycle Integrated Project (Outra)
2022/02 - 2022/07 Enzymes and proteins in prevention and therapy of Alzheimer’s Disease: State of art and perspectives (Mini-review)
Orientador de Joana Paixão e João Pedro Henriques
 Bachelor´s Degree, 1rst Cycle Integrated Project (PIC) (Outra)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020 - 2020 Polycaprolactone nanoparticles as carriers for delivery of enzymes into cells
Coorientador de Mariana Machado Correia da Cunha
 Bioengenharia e Nanossistemas (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/03 - 2017/11 Enzyme stabilization with solid-phase triazine-scaffolded biomimetic ligands
Orientador de Diogo Filipe Frazão Ferreira Faria
 Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 - 2017 Plasmid DNA purification with synthetic protein-mimic affinity ligands
Orientador de Ana Rita de Almeida Lourenço
 Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Fat Splitting Using Lipases
Coorientador de Mafalda Costa Artur Freixiela Dias
 Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Characterization of serological and antigenic reactivity in patients with severe malaria ('Caracterização da reatividade serológica e antigénica em pacientes com malária grave')
Coorientador de Janine Guerreiro Domingos
 Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Optimization of a MM-PBSA/GBSA protocol for the prediction of binding free energy of Bcl-xL inhibitors
Coorientador de João Pedro do Vale Hipólito Cavalheiro
 Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Heat-induced casein-whey protein interactions: influence of protein and mineral composition
Coorientador de Maria Aparício Nunes
 Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 - 2014 Development of novel biomimetic affinity adsorbents for plasmid DNA purification: Preliminary results
Orientador de Cátia Isabel Pereira Jorge
 Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 - 2013 Screening and evaluation of synthetic protein-mimic affinity ligands for the purification of plasmid DNA
Orientador de João Filipe Raimundo Belchior
 Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 - 2013 Establishment of a novel process for the purification of cutinase with triazine-scaffolded synthetic affinity ligands
Orientador de João Gonçalo Tereno Monteiro
 Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012 - 2012 Mechanisms underlying the high production of  IL-12 and IFN-ß by Lactobacillus acidophilus in dendritic cells
Coorientador de Daniela Filipa Martins Silva
 Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012 - 2012 Production and Purification of the p16INK4a: A Naked Mole-Rat’s Resistance Protein to Cancer
Coorientador de João Alberto Pacheco Marques de Vasconcelos e Sá
 Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2005 - 2010 A Novel Tool to Improve Protein Stability: Synthesis and Screening of Triazine-Scaffolded Affinity Ligands to Bind and Stabilise Cutinase
Orientador de Isabel Teixeira de Sousa
 Biotecnologia (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2004 - 2008 De Novo Design, Synthesis and Screening of Combinatorial Libraries of Affinity Ligands Directed Towards the Surface of Cutinase from Fusarium Solani Pisi
Orientador de Luisella Ruiu
 Biotecnologia (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2000 - 2004 Design, Synthesis and Evaluation of Immunoglobulin Binding Ligands: An Artificial Protein L.
Orientador de Ana Cecília Afonso Roque
 Biotecnologia (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
1999 - 2002 Design of Bacterial Vector Systems for the Secretion of Recombinant Proteins
Orientador de Filipe José Menezes Mergulhão
 Biotecnologia (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2000 - 2000 Isolation, characterization and application of monoclonal antibodies specific to cutinase from Fusarium solani pisi
Orientador de Suzana Maria da Silva Agostinho
 Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2000 - 2000 Precipitation studies with Eudragit S-100 : Immobilization and kinetics of lipase from Chromobacterium viscosum
Orientador de Ágata Ramos Rodrigues
 Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2000 - 2000 Derivatization of supports for immobilization of peptides and proteins with different biotechnological applications
Coorientador de Patrícia Rodrigues Saavedra Leirião
 Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal