???global.info.a_carregar???
Alina Secrieru. Concluiu o Mestrado em Ciências Farmacêuticas em 2017 pela Universidade do Algarve, Faculdade de Ciências e Tecnologia. Frequenta o Doutoramento em Química pela Universidade do Algarve desde 2019/02/01. Participa como Bolseiro de Doutoramento em 1 projeto de investigação. Nas suas atividades profissionais interagiu com 5 colaboradores em coautorias de 4 trabalhos científicos, nos quais consta o capítulo de um livro. Participou em vários eventos de cariz científico. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: Doença de Alzheimer; Quinolinas; Antimaláricos; drug repurposing; Química; Química medicinal; Biologia; Tuberculose; Pyrazolo[1,5-a]pyrimidines; proteómica química; pyrazoles; tautomerism; 3(5)-aminopyrazoles; Toxoplasma gondii; Plasmodium spp.; antimalarial drugs; endochin-like quinolones; endoperoxides; antimicrobial peptides.
Identification

Personal identification

Full name
Alina Secrieru

Citation names

  • Secrieru, Alina

Author identifiers

Ciência ID
0014-D52F-FF47

Email addresses

  • asecrieru@ualg.pt (Professional)

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Romanian (Mother tongue)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Elementary (A2) Intermediate (B1)
Russian Upper intermediate (B2) Upper intermediate (B2) Intermediate (B1) Upper intermediate (B2)
Education
Degree Classification
2019/02/01 - 2023/02/01
Ongoing
Química (Doutoramento)
Major in Química medicinal
Universidade do Algarve, Portugal
2017/12/05
Concluded
Mestrado Integrado em Ciências Farmacêuticas (Mestrado)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
"Síntese e avaliação in vitro da atividade de derivados de quinolina na hiperfosforilação de proteínas tau na Doença de Alzheimer" (THESIS/DISSERTATION)
17
Affiliation

Other Careers

Category
Host institution
Employer
2018/03/25 - 2018/12/20 Técnico Farmacêutico 1 Cl (Técnico Farmacêutico) Farmácia Rosa Nunes - José Carlos Nunes Duarte Unip. Lda, Portugal

Others

Category
Host institution
Employer
2017/09/01 - 2018/03/24 Voluntary Internship in Community Pharmacy Farmácia Rosa Nunes - José Carlos Nunes Duarte Unip. Lda, Portugal
2017/05/01 - 2017/08/15 Curricular Internship in Community Pharmacy Farmácia Rosa Nunes - José Carlos Nunes Duarte Unip. Lda, Portugal
2017/03/01 - 2017/04/30 Curricular Internship in Hospital Pharmacy Centro Hospitalar de Lisboa Ocidental EPE, Portugal
2016/07/25 - 2016/08/12 Extracurricular Internship in Hospital Pharmacy Klinicki centar Srbije, Serbia
2015/07/01 - 2015/08/01 Extracurricular Internship in Community Pharmacy Farmácia José Maceta, Portugal
Projects

Grant

Designation Funders
2019/02/01 - Current Development of pyrazolopyrimidines as anti-tuberculosis agents – hit-to-lead optimization and chemical proteomic target identification
SFRH/BD/140249/2018
PhD Student Fellow
Centro de Ciências do Mar, Portugal

Universidade do Algarve - Campus de Gambelas, Portugal

University of Liverpool Department of Chemistry, United Kingdom

Liverpool School of Tropical Medicine, United Kingdom
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Book chapter
  1. Horta, Pedro; Secrieru, Alina; Coninckx, Andy; Cristiano, Maria Lurdes Santos. "QUINOLONES FOR APPLICATIONS IN MEDICINAL CHEMISTRY: SYNTHESIS AND STRUCTURE". In Targets in Heterocyclic Systems, 260-297. Roma, Italy: Società Chimica Italiana, 2018.
    Published
Newspaper article
  1. Secrieru, Alina; Costa, Inês; O'Neill, Paul Michael; Cristiano, Maria Lurdes Santos. "Antimalarial Agents as Therapeutic Tools Against Toxoplasmosis—A Short Bridge between Two Distant Illnesses", Molecules, 2020, https://www.mdpi.com/1420-3049/25/7/1574.
  2. Secrieru, Alina; O'Neill, Paul Michael; Cristiano, Maria Lurdes Santos. "Revisiting the Structure and Chemistry of 3(5)-Substituted Pyrazoles", Molecules, 2019, https://doi.org/10.3390/molecules25010042.
  3. Horta, Pedro; Secrieru, Alina; Coninckx, Andy; Cristiano, Maria Lurdes Santos. "Quinolones in Medicinal Chemistry: are Potential Applications Compromised by Limited Synthetic Approaches?", Organic & Medicinal Chemistry International Journal, 2017, 10.19080/OMCIJ.2017.04.555647.
Thesis / Dissertation
  1. Secrieru, Alina. "Síntese e avaliação in vitro da atividade de derivados de quinolina na hiperfosforilação de proteínas tau na doença de Alzheimer". Master, 2017. http://hdl.handle.net/10400.1/10684.
Activities

Event participation

Activity description
Type of event
Event name
Institution / Organization
2019/03/18 - 2020/03/20 COST Action: EpiChemBio Training School "From Molecule to Medicine", held in Ljubljana, Slovenia
Conference
From Molecule to Medicine
Univerza v Ljubljani, Slovenia
2019/02/18 - 2019/02/20 Epigenetic Chemical Biology COST Action is a Scientific Workshop developed with the objective to establish the first European chemical biology network focused on epigenetics. The Action’s second objective is to increase awareness of epigenetics within the European scientific community and it will provide training for ESRs and emphasize involvement of COST inclusiveness targeted countries.
Workshop
COST CM1406 Epigenetic Chemical Biology
Centro de Ciências do Mar, Portugal

Universidade do Algarve - Campus de Gambelas, Portugal