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Raquel Costa holds a BSc and a MSc in Biochemistry, both from the Faculty of Sciences of the University of Porto. In 2017, she obtained her PhD in Metabolism from the Faculty of Medicine of the University of Porto (FMUP). Then, she was invited as assistant researcher in the Structured Program in bioengineered therapies for infectious diseases and tissue regeneration, funded by N2020, at FMUP and Instituto de Investigação em Saúde (i3S). Over the last years, she developed expertise in the field of diabetes and polyphenols, broadening her knowledge on the molecular mechanisms involved in diabetic metabolic and microvascular deregulation. Currently, she is a Co-PI of a EIT Health funded project envisioning the application of a biopolymer as a scaffold to be used in wound healing. Additionally, she is involved in translational research with an interventional clinical study 'XAN4Health' funded by a European Food Company, aiming to study the effect of the polyphenol xanthohumol on the Metabolic Syndrome progression, a disease interrelated with diabetes. She established international collaborations at the University of Vienna and the University of Santiago de Compostela, with experts in innovative oxidative stress measurements and specialized cell culture assays. Since the beginning of her research career, she was involved in several research projects which resulted in 40 original papers (h index of 17). She also published 2 book chapters and presented her work in +90 national and international scientific meetings and won 14 best presentation awards. She was also invited to lecturer of Biochemistry at Polytechnique Institute (Porto, PT) and FMUP, including the coordination of a curricular unit on Angiogenesis and Metabolism. Raquel was also invited to speak in seminars, workshops (1 international hands-on) in post-graduation national courses and was a member of the scientific and organizing committees of an international symposium on metabolism. For her expertise on metabolic disease and the discoveries in the crosstalk between angiogenesis and metabolism, she is guest editing of two special issues: 'Metabesity and Tissue Regeneration' in Int J Mol Sci (IF 4.183) and 'Women in Vascular Disease: from Pathology to Regenerative Engineering' in Biomolecules (IF 4.082) and is referee for 9 international ISI indexed journals.
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Identification

Personal identification

Full name
Maria Raquel Martins da Costa
Date of birth
1984/05/17
Gender
Female

Citation names

  • Costa, Raquel

Author identifiers

Ciência ID
0E1A-665B-7633
ORCID iD
0000-0002-9245-4565
Scopus Author Id
35810122000

Email addresses

  • mrcosta@med.up.pt (Professional)
  • raquel.costa@ibmc.up.pt (Professional)
  • raquel.costa22@gmail.com (Personal)

Addresses

  • Alameda Professor Hernâni Monteiro , 4200-319, Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2021/12/15 - 2022/02/25
Concluded
 Microbiologia Clínica da COVID-19: Diagnóstico Molecular e Saúde Pública (Outros)
Major in 14ECTS
Instituto Politécnico do Porto, Portugal
 Approved
2021/10 - 2022
Ongoing
 Clinical Investigator Certification - Level 2 (Outros)
Nova Medical School, Portugal

Universidade de Aveiro, Portugal
2020/10 - 2021/07
Concluded
 Training Course in Research Ethics/ Integrity (Outros)
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
2020/07 - 2020/07
Concluded
 Research Project Management (Outros)
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
2020/02
Concluded
 Clinical Investigator Certification - Level 1 (Outros)
Nova Medical School, Portugal

Universidade de Aveiro, Portugal
88%
2018/04
Concluded
 Basic and Intermediate Course of Statistics (SPSS) (Outros)
Speed Statistics, Portugal
2012 - 2017/07/07
Concluded
 Metabolism: Clinical and Experimental (Doutoramento)
Faculty of Medicine, University of Porto, Portugal

i3S - Instituto de Investigação e Inovação em Saúde, Portugal
"Polyphenols in diabetic vascular complications: from mechanisms to identification of therapeutic targets" (THESIS/DISSERTATION)
 Aprovada com distinção
2013/07
Concluded
 Laboratory Animal Science Training Course, FELASA C (Outros)
Universidade do Porto, Portugal
2009 - 2011/11/18
Concluded
 Biochemistry (Mestrado)
Faculty of Sciences, University of Porto, Portugal

Abel Salazar Institute, University of Porto, Portugal
"Modulation in vivo of angiogenesis, inflammation and oxidative stress in physiopathological conditions after consumption of a Xanthohumol supplemented beer" (THESIS/DISSERTATION)
 17
2003 - 2008
Concluded
 Biochemistry (Licenciatura)
Faculty of Sciences, University of Porto, Portugal

Abel Salazar Institute, University of Porto, Portugal
"Efeito do Bevacizumab, um anticorpo monoclonal humanizado, na angiogénese e suas implicações da patologia Degenerescência Macular pela Idade (DMI)" (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2022/06/01 - Current Invited Auxiliary Researcher (Research) Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
Portuguesa Centro de Biotecnologia e Química Fina, Portugal
2015/11/02 - 2022/05 Researcher (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/11/01 - 2019/12/31 Invited Auxiliary Researcher (Research) Universidade do Porto Faculdade de Medicina, Portugal
Faculty of Medicine, University of Porto, Portugal
2013/02 - 2016/12 Contracted Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
Faculty of Medicine, University of Porto, Portugal
2013/12 - 2014/02 Visiting Researcher (Research) Universidade de Santiago de Compostela, Spain
Hospital Clínico Universitario de Santiago de Compostela Servicio de Cardiología, Spain
2011/10 - 2012/12 Contracted Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
Faculty of Medicine, University of Porto, Portugal
(...)
2010/09 - 2012/11 Research Trainee (Research) Faculty of Sciences, University of Porto, Portugal
Faculty of Medicine, University of Porto, Portugal
2010/07 - 2011/09 Contracted Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
Faculty of Medicine, University of Porto, Portugal
(...)

Teaching in Higher Education

Category
Host institution 		Employer
2022/09 - Current Invited Assistant Professor (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
2020/10 - 2023/07 Invited Assistant Professor (University Teacher) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2020/02 - 2020/08 Invited Assistant Professor (University Teacher) Faculty of Medicine, University of Porto, Portugal
Faculty of Medical Dentistry, University of Porto, Portugal
Projects

Grant

Designation Funders
2023/03 - Current Bioactivity and regenerative potential of functionalized polycaprolactone-based skin dressings for diabetic foot ulcer management
Prize Bragança Parreira
Team member
Sociedade Portuguesa de Diabetologia, Portugal
Ongoing
2020/08 - Current Role as Co-PI in CyanoCare - development of products for skin protection and regeneration based on cyanobacteria
CyanoCarePAI2020
Principal investigator
EIT Health
Ongoing
2018/10 - Current XAN4Health – Effect of Xanthohumol consumption in metabolic syndrome progression. A clinical study
NCT03561116
Researcher
Company - TA XAN Development S.A.M.
Ongoing
2023/03/12 - 2024/09/11 Use of Aptamers towards Theranostics and Precision Medicine in Prostate Carcinoma
2022.09032.PTDC
team member
Fundação Ensino e Cultura Fernando Pessoa, Portugal

Instituto Politécnico do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/03/01 - 2024/08/31 Exploring SEX-specific DIFferences in ENDothelial (dys)function towards improved HFpEF management
2022.04344.PTDC
10.54499/2022.04344.PTDC
Team member
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2014/04 - 2015/08 RES4MED:learning medicine through research
134327
Researcher
Faculty of Medicine, University of Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/03 - 2013/08 AngioPaX - ELUCIDATING THE ANGIO/VASCULOGENIC PARADOX IN DIABETES
Provided by PTCRIS: 102083
102083
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
2010/02/05 - 2013/07/31 Team member of NPwhY - Innervation and angiogenesis for the benefit of osteogenesis: the involvement of NPY neuronal pathway in bone repair
PTDC/SAU-OSM/101469/2008
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal

Centre Hospitalier Universitaire Vaudois Service de pharmacologie clinique, Switzerland

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Garvan Institute of Medical Research, Australia

Universidade do Porto Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/02 - 2013/07 NPwhY - Innervation and angiogenesis for the benefit of osteogenesis: the involvement of NPY neuronal pathway in bone repair
Provided by PTCRIS: 101469
101469
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
2008/12 - 2009/10 Effect of beer polyphenols in modulation of inflammation and angiogenesis
Institute of Beverages and Health(iBeSa)
Principal investigator
Faculty of Medicine, University of Porto, Portugal
 SuperBock
Concluded

Contract

Designation Funders
2022/01/02 - 2024/01/01 FAt DieT-induced ObesiTY in MElanoma metaStaSis
EXPL/SAU-NUT/0843/2021
10.54499/EXPL/SAU-NUT/0843/2021
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Instituto de Astrofísica e Ciências do Espaço, Portugal

Instituto Politécnico do Porto, Portugal

Universidade do Porto Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 Unidade de Ciências Biomoleculares Aplicadas
UID/Multi/04378/2019
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 Institute for Research and Innovation in Health Sciences
UID/BIM/04293/2019
LA/P/0070/2020
10.54499/LA/P/0070/2020
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2017/11 - 2019/12 Structured Program on Bioengineering Therapies for Infectious Diseases and Tissue Regenerations
NORTE-01-0145-FEDER-000012
Invited Scientist Fellow
Faculty of Medicine, University of Porto, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
NORTE 2020
Concluded
2017/02 - 2017/07 Advanced formation - PhD programs
NORTE-08-5369-FSE-000018
 Fundação para a Ciência e a Tecnologia
2013/01/01 - 2016/12 Polyphenols in diabetic vascular complications: from mechanisms to identification of therapeutic targets
SFRH/BD/86895/2012
PhD Student Fellow
Faculty of Medicine, University of Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2013/01 - 2016/12 Beer Polyphenols in Diabetic Vascular Complications: From Mechanisms to Identification of Therapeutic Targets
FCT/SFRH/BD/868952/2012
 Fundação para a Ciência e a Tecnologia
2011 - 2012 New antitumor and antiangiogenic heterocyclic compounds: synthesis, molecular modeling, screening of enzymatic inhibition and studies in tumor and endothelial cell lines with tyrosine kinase membrane receptors as targets
PTDC/QUI-QUI/111060/2009
Research Fellow
Fundação para a Ciência e a Tecnologia
Concluded
2010/07 - 2011/09 Smart joint implants using bionanocomposites-(SIMBIO)
NANO/NMed-SD/0156/2007
Research Fellow
Fundação para a Ciência e a Tecnologia

Other

Designation Funders
2020/01/01 - 2023/12/31 Applied Molecular Biosciences Unit
UIDB/04378/2020
10.54499/UIDB/04378/2020
Universidade do Porto, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade NOVA de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Costa, Raquel; Raquel Soares; Raquel Costa Almeida. Corresponding author: Costa, Raquel. "Polyphenols-Based Nanoparticles as Multifaceted Diabetes Modulators". In Nanotechnology in the Life Sciences, edited by Natalia Martins. Switzerland: Springer Nature, 2020.
    Published
  2. Costa, Raquel; Sara Andrade; Pedro Coelho; Susana Gomes Guerreiro; Raquel Soares. "Breaking the borders between obesity and cancer". In Recent Advances in Obesity, edited by Rosário Monteiro; Maria João Martins, 398-422. Sharjah, United Arab Emirates: Bentham Science Publishers, 2020.
    Published
  3. Raquel Costa-Almeida; Raquel Soares; Raquel Costa. "Polyphenol-based nanoparticles as multifaceted diabetes modulators". edited by Devarajan Thangadurai; Jeyabalan Sangeetha; Ram Prasad, 251-270. Springer Science and Business Media B.V., 2020.
    10.1007/978-3-030-41464-1_11
  4. Soares, Raquel; Negrão, Rita; Costa, Raquel. "Efeito de polifenóis presentes na cerveja na modulação da angiogénese e inflamação". In iBeSa, 127-150. 2010.
Conference abstract
  1. Beatriz G. Bernardes; Valentina Rossa; Magalhães,Rui; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "In vitro assessment of silk fibroin aerogel particles loaded with adenosine for wound healing". 2023.
  2. Beatriz G. Bernardes; Sara Baptista da Silva; Carlos Illanes-Bordomás; Rui Magalhães; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Supercritical CO2 technology for the fabrication of silk fibroin aerogel particles for wound healing and regeneration". 2022.
  3. Beatriz G. Bernardes; Valentina Rossa; Sara Baptista da Silva; Magalhães,Rui; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Adenosine-loaded silk fibroin aerogel particles for wound healing". 2022.
  4. Beatriz G. Bernardes; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Nova abordagem terapêutica para a cicatrização de feridas à base de partículas de seda". 2022.
  5. Beatriz G. Bernardes; Sara Baptista da Silva; Carlos Illanes-Bordomás; Rui Magalhães; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Silk fibroin aerogel particles for a wound healing treatment". 2022.
  6. Beatriz G. Bernardes; Pasquale del Gaudio; Paulo Alves; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Bio-aerogéis". 2021.
  7. Silva, Sara; Bernardes, Beatriz; Borges, Sandra; Pintado, Maria Manuela; Granja, Pedro L.; Soares, Raquel; Costa, Raquel; Oliveira, Ana L.. "In Situ Antioxidant Activity of an Enzymatically Crosslinked Sericin Hydrogel for Healing of Chronic Wounds". Paper presented in 31st Conference of the European Society for Biomaterials, Porto, 2021.
    Accepted
  8. Bernardes, Beatriz; Costa, Raquel; García-González, Carlos A.; Oliveira, Ana L.. "Silk Fibroin aerogel particles for chronic wound healing". Paper presented in Athens conference in advances in chemistry, Athens, 2021.
    Published
  9. "Avaliação do potencial anti tumoral de fármacos antidiabéticos em cancro de próstata. Revista Portuguesa de Diabetes". Paper presented in 17º Congresso da Sociedade Portuguesa de Diabetes, Vilamoura, 2021.
    Published
  10. "Efeito da testosterona e estradiol no paradoxo diabetes/cancro de próstata. Revista Portuguesa de Diabetes". Paper presented in 17º Congresso Nacional de Diabetes, Vilamoura, 2021.
    Published
  11. "Aplicação de um hidrogel de sericina em feridas crónicas de animais com diabetes tipo 2. Revista Portuguesa de Diabetes". Paper presented in 17º Congresso da Sociedade Portuguesa de Diabetes, Vilamoura, 2021.
    Published
  12. "Prostate cancer cell lines inhibition by umbilical cord blood serum. Stem cells translational medicine". Paper presented in Cord Blood Connect, 2021.
    Published
  13. Beatriz G. Bernardes; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Unravelling the potential of bioaerogels in fluid management, healing, and regeneration of wounds". 2021.
  14. Beatriz G. Bernardes; Clara López-Iglesias; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Silk fibroin aerogel particles via the emulsion-gelation method for the treatment of chronic wounds". 2021.
  15. Beatriz G. Bernardes; Sara Baptista da Silva; Sandra Borges; Pintado, M.; P. L. Granja; R. Soares; Raquel Costa; A. L. Oliveira. "In situ antioxidant activity of an enzymatically crosslinked sericin hydrogel towards chronic wound healing". 2021.
  16. Beatriz G. Bernardes; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Silk fibroin aerogel particles for a wound healing treatment". 2021.
  17. Beatriz G. Bernardes; Clara López-Iglesias; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Structure and properties of silk fibroin-based aerogel particles prepared by emulsion-gelation followed by supercritical CO2 for wound healing". 2021.
  18. Costa, Raquel. Corresponding author: Costa, Raquel. "Efeito de um hidrogel de sericina na cicatrização de feridas crónicas num modelo animal de diabetes tipo 2. Revista Portuguesa de Diabetes". Paper presented in Congresso da Sociedade Portuguesa de Diabetologia, Vilamoura, 2020.
    Published
  19. Costa, Raquel. Corresponding author: Costa, Raquel. "A metformina inibe a angiogénese e a formação de colagénio em HMEC-1 em condições de hiperglicemia. Revista Portuguesa de Diabetes". Paper presented in Congresso da Sociedade Portuguesa de Diabetologia, Vilamoura, 2020.
    Published
  20. Costa, Raquel. "Prostate cancer cell PC3 behavior under a simulated type 2 diabetic microenvironment. Revista Portuguesa de Diabetes". Paper presented in Congresso da Sociedade Portuguesa de Diabetologia, Vilamoura, 2020.
    Published
  21. Costa, Raquel. Corresponding author: Costa, Raquel. "Anti-angiogenic potential of açaí-derived polyphenols: an in vitro approach. J Food Science". Paper presented in 2nd Conference on Innovations in Food Science & Human Nutrition, London, 2019.
    Published
  22. Costa, Raquel. "Modulation of Human Endothelial Cell Angiogenic Processes by Platelets from Patients with Stickle Cell Disease. Blood". Paper presented in 61st ASH Annual Meeting & Exposition, Orlando, 2019.
    Published
  23. Costa, Raquel. Corresponding author: Costa, Raquel. "Screening of phenolic compounds in açaí and evaluation of its anti-angiogenic activity. Food Res Int". Paper presented in XXEuroFoodChem, Porto, 2019.
    Published
  24. Costa, Raquel. Corresponding author: Costa, Raquel. "Diet-derived Xanthohumol ameliorate diabetic-related dysfunctions in mice. J Food Science". Paper presented in 2nd Conference on Innovations in Food Science & Human Nutrition, London, 2019.
    Published
  25. Costa, Raquel. Corresponding author: Costa, Raquel. "Modulação metabólica e vascular por polifenóis da dieta num modelo animal de diabetes tipo 2. Revista Portuguesa de Diabetes". Paper presented in Congresso da Sociedade Portuguesa de Diabetologia, Vilamoura, 2018.
    Published
  26. Costa, Raquel. "Acute Hemolysis induces pro-angiogenic molecule production and neovascularization in vivo. Blood". Paper presented in ASH Annual Meeting and Exposition, California, 2018.
    Published
  27. Costa, Raquel. "A hemólise aguda induz processos inflamatórios e angiogénicos in vivo. Hematol transfus cell ther". Paper presented in Congresso Brasileiro de Hematologia, Hemoterapia e Terapia Celular - HEMO, Campinas, 2018.
    Published
  28. Costa, Raquel. "Efeitos das plaquetas de pacientes com anemia falciforme em processos angiogénicos de células endoteliais. Hematol transfus cell ther". Paper presented in Congresso Brasileiro de Hematologia, Hemoterapia e Terapia Celular - HEMO, Campinas, 2018.
    Published
  29. Costa, Raquel. "Effects of AICAR, Compound C and Metformin administration in metabolic and angiogenic behavior in human microvascular endothelial cells (HMECs). Revista Portuguesa de Diabetes". Paper presented in Congresso da Sociedade Portuguesa de Diabetologia, Vilamoura, 2018.
    Published • 10.1055/s-0038-1644388
  30. Costa, Raquel. "Endothelial metabolism impacts on vascular behavior in type 1 diabetic mice. Revista Portuguesa de Diabetes". Paper presented in Congresso da Sociedade Portuguesa de Diabetologia, Vilamoura, 2018.
    Published
  31. Costa, Raquel. "Xanthohumol restores hepatic glucolipid metabolism balance in type 1 diabetic Wistar rats. Revista portuguesa de diabetes". Paper presented in Simpósio em Metabolismo, Porto, 2016.
    Published
  32. Costa, Raquel. Corresponding author: Costa, Raquel. "Polyphenols as diabetic modulators: Relevance to angiogenic paradox. Revista portuguesa de diabetes". Paper presented in Simpósio em Metabolismo, Porto, 2016.
    Published
  33. Costa, Raquel. "Modulation of VEGF-B signaling in obesity by DDE exposure. Revista portuguesa de diabetes". Paper presented in Simpósio em Metabolismo, Porto, 2016.
    Published
  34. Costa, Raquel. "Unveiling the role of vasculogenesis in diabetic erectile dysfunction using a bone marrow transplantation model: preliminary results. The Journal of Sexual Medicine". Paper presented in 18th Congress of the European Society of Sexual Medicine, Madrid, 2016.
    Published
  35. Costa, Raquel. Corresponding author: Costa, Raquel. "O consumo de polifenóis modula as alterações vasculares na diabetes mellitus tipo 2. Revista Portuguesa de Diabetes". Paper presented in Congresso da Sociedade Portuguesa de Diabetologia, Vilamoura, 2016.
    Published
  36. Costa, Raquel. "Evidence for a derangement of the microvascular system in patients with a very early diagnosis of systemic sclerosis. Journal of Scleroderma and Related Disorders". Paper presented in 4th Systemic Sclerosis World Congress, Lisbon, 2016.
    Published
  37. Costa, Raquel. Corresponding author: Costa, Raquel. "Polyphenol consumption modulates angiogenic pathways in diabetes mellitus type 2. Porto Biomedical Journal". Paper presented in Simpósio em Metabolismo, Porto, 2016.
    Published • 10.1055/s-0039-1688334
  38. Costa, Raquel. Corresponding author: Costa, Raquel. "Efeito dos polifenóis nas complicações vasculares e metabólicas associadas à diabetes mellitus tipo 2. Revista Portuguesa de Diabetes". Paper presented in Simpósio em Metabolismo, Porto, 2015.
    Published
  39. Costa, Raquel. "Relação entre galactina-3 e produtos de glicação avançada (AGE): O caminho para melhorar a saúde cardíaca em diabetes mellitus tipo 2. Revista Portuguesa de Diabetes". Paper presented in Simpósio em Metabolismo, Porto, 2015.
    Published
  40. Costa, Raquel. Corresponding author: Costa, Raquel. "Efeito dos polifenóis nas complicações vasculares associadas à diabetes mellitus tipo 2. Revista Portuguesa de Diabetes". Paper presented in Congresso da Sociedade Portuguesa de Diabetologia, Tomar, 2015.
    Published
  41. Costa, Raquel. "Efeito dos polifenóis na expressão da galactina-3 num modelo de rato diabético. Revista Portuguesa de Diabetes". Paper presented in Congresso da Sociedade Portuguesa de Diabetologia, 2015.
    Published
  42. Costa, Raquel. Corresponding author: Costa, Raquel. "Complicações vasculares associadas à diabetes mellitus tipo 2. Revista portuguesa de diabetes". Paper presented in Congresso da Sociedade Portuguesa de Diabetologia, Porto, 2014.
    Published
  43. Costa, Raquel. "A inibição da survivina reverte a remodelação cardíaca e pulmonar na hipertensão arterial pulmonary induzida pela monocrotalina. Revista Portuguesa de Cardiologia". Paper presented in XXXV Congresso Português de Cardiologia, Albufeira, 2014.
    Published
  44. Costa, Raquel. "“Synthesis Molecular Docking and Biological Evaluation of new 1-Aryl-3-[3-(thieno[3,2-b]pyridin-7-ylthio)phenylureas as Potent Type II VEGFR-2 Tyrosine Kinase Inhibitors” Conference CHEMMEDCHEM". Paper presented in CHEMMEDCHEM, Lisbon, 2014.
    Published
  45. Silva, Ana Filipa; Ferreira-Pinto, Manuel J.; Justino, Joana; Nogueira-Ferreira, Rita; Padrão, Ana Isabel; Moreira-Gonçalves, Daniel; Carneiro, Fábio; et al. "A inibição de survivina reverte a remodelação cardíaca e pulmonar na hipertensão arterial pulmonar induzida pela monocrotalina". Paper presented in Congresso Português de Cardiologia, 2014.
    Published
  46. Ferreira-Pinto, Manuel João; Silva, Ana Filipa; Justino, Joana; Ferreira, Rita M.N.; Padrão, Ana Isabel; Moreira-Gonçalves, Daniel; Carneiro, Fábio; et al. "Survivin Inhibition Reverses Cardiac and Pulmonary Remodeling in Monocrotaline-Induced Pulmonary Arterial Hypertension". Paper presented in American Heart Association Scientific Sessions, 2013.
    Published
  47. Costa, Raquel. "Survivin role in pulmonary arterial hypertension. European heart journal". Paper presented in XXXIV Congresso Português de Cardiologia, Albufeira, 2013.
    Published
  48. Costa, Raquel. "Vascular impairment associated with diabetic condition. Porto Biomedical Journal". Paper presented in Simpósio em Metabolismo, Porto, 2013.
    Published
  49. Costa, Raquel. "Anti-angiogenic effects of new di(hetero)arylthioethers 1,3-diarylureas in the thieno[3,2-b]pyridine series. Role in VEGFR2 inhibition. Porto Biomedical Journal". Paper presented in Simpósio em Metabolismo, Porto, 2013.
    Published
  50. Costa, Raquel. "Expression and localization of tyrosine hydroxylase in mice adipose tissue under obesity. Revista Portuguesa de Cirurgia". 2013.
    Published
  51. Costa, Raquel. "Tyrosine hydroxylase localization in mice adipose tissue under obesity. Mol Biol Cell". Paper presented in ASCB Annual Meeting, New Orleans, 2013.
    Published
  52. Silva, Ana Filipa; Ferreira-Pinto, Manuel João; Ferreira, Rita; Padrão, Ana Isabel; Moreira-Gonçalves, Daniel; Carneiro, Fábio; Brandão, Joana; et al. "Papel da Survivina na Hipertensão Arterial Pulmonar". Paper presented in Congresso Português de Cardiologia, 2013.
    Published
  53. Silva, João Pedro; Ramos, Reinaldo; Rodrigues, Ana Cristina; Costa, Raquel; Guardao, Luisa; Soares, Raquel; Vilanova, Manuel; Domingues, Lucilia; Gama, F. Miguel. "Bioactivity of the recombinant human antimicrobial peptide LL37: a key role in wound healing through vascularization. Published in Journal of Tissue Engineering and Regenerative Medicine". Paper presented in TERMIS-EU Annual Meeting, 2012.
  54. Pirraco, Ana; Coelho, Pedro; Rocha, Ana; Costa, Raquel; Soares, Raquel. "Imatinib mesylate presents a cytostatic effect on B16 cells in vitro and an apoptotic outcome in melanoma in vivo". Paper presented in Experimental Biology 2009, New Orleans, 2009.
    Published • 10.1096/fasebj.23.1_supplement.625.14
Conference paper
  1. Beatriz G. Bernardes; Sara Baptista da Silva; Carlos Illanes-Bordomás; Magalhães,Rui; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Development of self-assembled aerogel silk particles for wound healing". 2022.
    10.3217/978-3-85125-903-2
  2. Beatriz G. Bernardes; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Self-assembled silk fibroin aerogel particles for wound healing". 2022.
  3. Bernardes, Beatriz; Costa, Raquel; García-González, Carlos A.; Oliveira, Ana Leite. "Development of self-assembled silk fibroin particles for wound healing". 2022.
  4. Costa, Raquel; Soares, Raquel; Negrão, Rita. "Effect of beer polyphenols in the modulation of angiogenesis and inflammation". Paper presented in 7ª Jornada Bebidas e Saúde (IBeSa), 2010.
    Published
Conference poster
  1. Reis, Ana; Rocha, Sara; Dias, Irundika H.K.; Costa, Raquel; Soares, Raquel; Sanchez-Quesada, José Luis; Perez, Antonio. Corresponding author: Reis, Ana. "The impact of T2DM on the bioavailability of microbial (poly)phenol metabolites: looking into the dynamics of lipoproteins and endothelial cells". Paper presented in 1st FEBS Redox Medicine Workshop: from cellular signaling to systems physiology and therapeutic targets, 2023.
  2. Beatriz G. Bernardes; Valentina Rossa; Magalhães,Rui; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Unleashing the healing potential of adenosine". 2023.
  3. Anabela Veiga; Sara Baptista da Silva; Olivia Foster; Raquel Costa; Dr. Viviana Ribeiro; Filipa Castro; Fernando Rocha; David L. Kaplan. "Silk sericin hydrogels as a promising sustainable platform for skin tissue engineering". 2023.
  4. Beatriz G. Bernardes; Sara Baptista da Silva; Carlos Illanes-Bordomás; Magalhães,Rui; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Silk fibroin aerogel particles for a wound healing treatment". 2022.
  5. Beatriz G. Bernardes; Valentina Rossa; Sara Baptista da Silva; Magalhães,Rui; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Adenosine-loaded silk fibroin aerogel particles for wound healing". 2022.
  6. Beatriz G. Bernardes; Sara Baptista da Silva; Carlos Illanes-Bordomás; Magalhães,Rui; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Supercritical CO2 technology for the fabrication of silk fibroin aerogel particles for wound healing and regeneration". 2022.
  7. Beatriz G. Bernardes; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Unravelling the potential of bioaerogels in fluid management, healing, and regeneration of wounds". 2021.
  8. Guerra, Ana; Costa, Raquel; Rodrigues, Ilda; Neves, Catarina; Vieira, Hugo; Ferreira, Sílvia; Sousa, SI; et al. "Modulation of VEGFB signaling by DDE exposure in obesity". Paper presented in ECO, Viena, Áustria, 2018.
  9. Campos Silva, Carolina; Rodrigues, Ilda; Costa, Raquel; Sampaio-Pinto, Vasco; Nascimento, Diana; Pinto-do-Ó, Perpétua; Soares, Raquel; Andrade, Sara. "Angiogenic paradox in type 1 diabetes: analysis of genes associated with metabolism and angiogenesis". Paper presented in 5th Annual Meeting I3S, Póvoa do Varzim, Portugal, 2016.
    10.1109/iwssip.2013.6623464
  10. Guerra, Ana; Costa, Raquel; Rodrigues, Ilda; Neves, Catarina; Vieira, Hugo; Ferreira, Sílvia; Calhau, Conceição; Pestana, Diogo; Negrão, Rita. "Modulation of VEGF-B signaling in obesity by DDE exposure". Paper presented in 5th Annual Meeting I3S, Póvoa do Varzim, Portugal, 2016.
  11. Costa, Raquel; Rodrigues, Ilda; Guardão, Luísa; Quelhas Lima, Joana; Sousa, Emilia; Soares, Raquel; Negrão, Rita. "Polyphenol-induced modulation of VEGF signaling in diabetes: Unveiling the angiogenic paradox and metabolism interplay". Paper presented in 5th Annual Meeting I3S, Póvoa do Varzim, Portugal, 2016.
  12. Luís, Carla; Costa, Raquel; Castela, Angela; Rodrigues, Ilda; Coelho, Pedro; Gomes J,; Reis, Celso; Soares, Raquel. "Expression of Galectin-3 and Nitrotyrosine in a Type-2 Diabetic Mellitus mouse model". Paper presented in IJUP 2015, 2015.
    10.5220/0007510901690173
  13. Costa, Raquel; Almeida, Raquel; Rodrigues, Ilda; Guardão, Luísa; Guimarães, João Tiago; Negrão, Rita; Soares, Raquel. "Complicações vasculares associadas à diabetes Mellitus tipo 2". Paper presented in 11.º Congresso Português de Diabetes, 2014.
    10.1055/s-0038-1674594
Journal article
  1. Beatriz G. Bernardes; Sara Baptista da Silva; Carlos Illanes-Bordomás; Magalhães,Rui; Juliana Rosa Dias; Nuno M. F. Alves; Raquel Costa; Carlos A. García-González; A. L. Oliveira. "Expanding the potential of self-assembled silk fibroin as aerogel particles for tissue regeneration". Pharmaceutics 15 11 (2023): https://ciencia.ucp.pt/en/publications/e0d24d15-4870-42bf-bfbd-759e7fc45f06.
    10.3390/pharmaceutics15112605
  2. Carla Luís; André P. Sousa; Raquel Costa; Ana T. Maduro; Patrick J. Pais; Sara Sá; Álvaro Gestoso; et al. "Exploring the Anti-Cancer Properties of Pomegranate Peel Aqueous Extract". Applied Sciences (2023): https://doi.org/10.3390/app132111773.
    10.3390/app132111773
  3. André Sousa; Pedro Coelho; Fernanda Leite; Catarina Teixeira; Ana Catarina Rocha; Inês Santos; Pilar Baylina; et al. "Impact of umbilical cord mesenchymal stromal/stem cell secretome and cord blood serum in prostate cancer progression". Human Cell 36 3 (2023): 1160-1172. https://ciencia.ucp.pt/en/publications/a9db6981-8d9b-4bb8-b635-7913f5d5745f.
    10.1007/s13577-023-00880-z
  4. Ana T. Maduro; Anabela Pinto; Joana Ferreira-Gomesb; Raquel Costa; Raquel Soares; Carla Luís. "Increased galactosidase beta 1 expression as a senescent key factor in ß-cells function modulation at the early steps of type 2 diabetes". Experimental and Clinical Endocrinology and Diabetes 131 5 (2023): 282-289. https://ciencia.ucp.pt/en/publications/24b16a89-343e-4287-8cfe-d798187b585a.
    10.1055/a-2044-8873
  5. Inês Guimarães; Raquel Costa; Sara Madureira; Sandra Borges; A. L. Oliveira; Pintado, M.; Sara Baptista da Silva. "Tannic acid tailored-made microsystems for wound infection". International Journal of Molecular Sciences 24 5 (2023): 1-18. https://ciencia.ucp.pt/en/publications/18b89a94-fc94-4ee5-ac7c-5ad9384b7d36.
    10.3390/ijms24054826
  6. Ana Reis; Sara Rocha; Irundika HK. Dias; Raquel Costa; Raquel Soares; José Luis Sánchez-Quesada; Antonio Perez; Victor de Freitas. "Type 2 Diabetes mellitus alters the cargo of (poly)phenol metabolome and the oxidative status in circulating lipoproteins". Redox Biology 59 (2023): https://ciencia.ucp.pt/en/publications/1f90a4bc-d40d-4e57-87cd-fbb04429f5e1.
    10.1016/j.redox.2022.102572
  7. Marzieh Moeenfard; Maria João Pena; Pedro Barata; Raquel Soares; Raquel Costa. "Effect of Raw and Roasted Phoenix dactylifera L. Seed Polyphenols Extracts on Suppression of Angiogenesis in Endothelial Cells". Plant Foods for Human Nutrition (2022): https://doi.org/10.1007/s11130-022-01003-z.
    10.1007/s11130-022-01003-z
  8. Sara Baptista-Silva; Beatriz G. Bernardes; Sandra Borges; Ilda Rodrigues; Rui Fernandes; Susana Gomes-Guerreiro; Marta Teixeira Pinto; et al. "Exploring Silk Sericin for Diabetic Wounds: An In Situ-Forming Hydrogel to Protect against Oxidative Stress and Improve Tissue Healing and Regeneration". Biomolecules 12 6 (2022): 801-801. https://doi.org/10.3390/biom12060801.
    10.3390/biom12060801
  9. André P. Sousa; Raquel Costa; Marco G. Alves; Raquel Soares; Pilar Baylina; Rúben Fernandes. "The impact of metabolic syndrome and type 2 diabetes mellitus on prostate cancer". Frontiers in Cell and Developmental Biology 10 (2022): https://ciencia.ucp.pt/en/publications/31e2d70e-eb12-41ff-a014-eb21a9a0e72e.
    10.3389/fcell.2022.843458
  10. Raquel Costa; André Sousa; Pedro Coelho; Fernanda Leite; Ruben Fernandes; Pilar Baylina; Raquel Soares; Andreia Gomes. Corresponding author: Raquel Costa. "Impact of umbilical cord mesenchymal stem cells secretome and cord blood serum in prostate cancer progression". Cell Tissue Res (2022):
    Submitted
  11. Sara Rocha; Irundika Dias; Raquel Costa; Raquel Soares; José Luís Sanchéz-Quesada; Ana Reis; Víctor Freitas. "Type 2 diabetes alters the cargo of (poly)phenol metabolome and oxidative status in circulating lipoprotein populations". Redox Biology (2022):
    Submitted
  12. Sara Batista-Silva; Beatriz G. Bernardes; Sandra Borges; Ilda Rodrigues; Rui Fernandes; Susana Gomes-Guerreiro; Marta Teixeira-Pinto; et al. Corresponding author: Raquel Costa. "Exploring silk sericin for diabetic wounds: an in situ forming hydrogel to protect against oxidative stress and improve tissue healing and regeneration". Biomolecules (2022):
    Accepted
  13. Marzieh Mooenfard; Maria João Pena; Pedro Barata; Raquel Soares; Costa, Raquel. Corresponding author: Costa, Raquel. "Anti-angiogenic Activity of Raw and Roasted Date Seed Polyphenol Extracts (Kabkab cultivar) on Human Microvascular Endothelial Cells". Journal of Nutritional Biochemistry (2022):
    Submitted
  14. Teresa Maduro; Anabela Silvestre; Joana Gomes; Costa, Raquel; Raquel Soares; Carla Luis. "Increased GLB1 expression as a senescent key factor in ß-cells function modulation at the early steps of type 2 diabetes". Journal of Diabetes and its complications (2022):
    Submitted
  15. Carla Luis; André Sousa; Costa, Raquel; Carla Guedes; Frantz Gojon; Patrick Dias; Flávia Fernandes; et al. "The anti-cancer potential of Pomegranate Peel Extract". Journal of Nutrition Biochemistry (2022):
    Submitted
  16. Correia, Joana; Costa, Raquel; Prudêncio, Cristina; Soares, Raquel; Coelho, Pedro. "Fattymess: fat diet-induced obesity in melanoma metastasis". (2022): http://hdl.handle.net/10400.22/23959.
    10.26537/recipp-23959
  17. Maria João Pena; Raquel Costa; Ilda Rodrigues; Sandra Martins; João Tiago Guimarães; Ana Faria; Conceição Calhau; Júlio César Rocha; Nuno Borges. "Unveiling the Metabolic Effects of Glycomacropeptide". International Journal of Molecular Sciences 22 18 (2021): 9731-9731. https://doi.org/10.3390/ijms22189731.
    Published • 10.3390/ijms22189731
  18. Raquel Costa; André Sousa; Raquel Soares; Andreia Gomes. "Prostate cancer cell lines inhibition by umbilical cord blood serum". Stem cells translational medicine 10 S1 (2021): S3-S3. https://ciencia.ucp.pt/en/publications/5de7e119-b85e-43e7-ba60-8244ab976863.
    10.1002/sct3.13012
  19. Carolina Silva; Ilda Rodrigues; Sara Andrade; Raquel Costa; Raquel Soares. "Metformin reduces vascular assembly in high glucose-treated human microvascular endothelial cells in an ampk-independent manner". Cell Journal 23 2 (2021): 174-183. https://ciencia.ucp.pt/en/publications/afc867e8-dec1-4d66-b18c-dd2ec3ae6a8d.
    10.22074/cellj.2021.7212
  20. Beatriz G. Bernardes; Pasquale Del Gaudio; Paulo Alves; Raquel Costa; Carlos A. García-Gonzaléz; Ana Leite Oliveira. Corresponding author: Raquel Costa. "Bioaerogels: Promising Nanostructured Materials in Fluid Management, Healing and Regeneration of Wounds". Molecules 26 13 (2021): 3834-3834. https://doi.org/10.3390/molecules26133834.
    Published • 10.3390/molecules26133834
  21. "Metformin Reduces Vascular Assembly in High Glucose-Treated Human Microvascular Endothelial Cells in An AMPK-Independent Manner". Cell Journal 23 2 (2021): 174-183. https://pubmed.ncbi.nlm.nih.gov/34096218/.
    Published
  22. Gomes, Andreia; Coelho, Pedro; Soares, Raquel; Costa, Raquel. "Human umbilical cord mesenchymal stem cells in type 2 diabetes mellitus: the emerging therapeutic approach". Cell and Tissue Research 385 3 (2021): 497-518. http://dx.doi.org/10.1007/s00441-021-03461-4.
    Open access • Published • 10.1007/s00441-021-03461-4
  23. Raquel Costa; Daniela Azevedo; Pedro Barata; Raquel Soares; Luís F. Guido; Daniel O. Carvalho. "Antiangiogenic and Antioxidant In Vitro Properties of Hydroethanolic Extract from açaí (Euterpe oleracea) Dietary Powder Supplement". Molecules 26 7 (2021): 2011-2011. https://doi.org/10.3390/molecules26072011.
    Open access • Published • 10.3390/molecules26072011
  24. Baptista-Silva, Sara; Borges, Sandra; Costa-Pinto, Ana Rita; Costa, Raquel; Amorim, Manuela; Dias, Juliana R.; Ramos, Óscar; et al. "In Situ Forming Silk Sericin-Based Hydrogel: A Novel Wound Healing Biomaterial". ACS Biomaterials Science & Engineering 7 4 (2021): 1573-1586. http://dx.doi.org/10.1021/acsbiomaterials.0c01745.
    Published • 10.1021/acsbiomaterials.0c01745
  25. Costa, Raquel; Costa, Luís; Rodrigues, Ilda; Meireles, Catarina; Soares, Raquel; Tamagnini, Paula; Mota, Rita. "Biocompatibility of the Biopolymer Cyanoflan for Applications in Skin Wound Healing". Marine Drugs 19 3 (2021): 147-147. http://dx.doi.org/10.3390/md19030147.
    Open access • Published • 10.3390/md19030147
  26. Cordeiro, Adryana; Costa, Raquel; Andrade, Nelson; Silva, Cláudia; Canabrava, Natalia; Pena, Maria João; Rodrigues, Ilda; Andrade, Sara; Ramalho, Andrea. "Does adipose tissue inflammation drive the development of non-alcoholic fatty liver disease in obesity?". Clinics and Research in Hepatology and Gastroenterology 44 4 (2020): 394-402. http://dx.doi.org/10.1016/j.clinre.2019.10.001.
    Published • 10.1016/j.clinre.2019.10.001
  27. Luís, Carla; Costa, Raquel; Rodrigues, Ilda; Castela, Ângela; Coelho, Pedro; Guerreiro, Susana; Gomes, Joana; Reis, Celso; Soares, Raquel. "Xanthohumol and 8-prenylnaringenin reduce type 2 diabetes associated oxidative stress by downregulating galectin-3". Porto Biomedical Journal 4 1 (2019): e23. http://dx.doi.org/10.1016/j.pbj.0000000000000023.
    Published • 10.1016/j.pbj.0000000000000023
  28. Gomes, A.; Soares, R.; Costa, R.; Marino, F.; Cosentino, M.; Malagon, M.M.; Ribeiro, L.. "High-fat diet promotes adrenaline production by visceral adipocytes". European Journal of Nutrition (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85064732574&partnerID=MN8TOARS.
    10.1007/s00394-019-01971-0
  29. Silva, C.; Sampaio-Pinto, V.; Andrade, S.; Rodrigues, I.; Costa, R.; Guerreiro, S.; Carvalho, E.; et al. "Establishing a link between endothelial cell metabolism and vascular behaviour in a type 1 diabetes mouse model". Cellular Physiology and Biochemistry 52 3 (2019): 503-516. http://www.scopus.com/inward/record.url?eid=2-s2.0-85063676424&partnerID=MN8TOARS.
    10.33594/000000036
  30. Gotardo, Erica M.F.; Chweih, Hanan; Brito, Pamela L.; Leonardo, Flavia C.; Costa, Raquel; Soares, Raquel; Costa, Fernando F.; Conran, Nicola. "Acute Hemolysis Induces Pro-Angiogenic Molecule Production and Neovascularization In Vivo". Blood 132 Supplement (2018): 3608-3608. http://dx.doi.org/10.1182/blood-2018-99-118416.
    10.1182/blood-2018-99-118416
  31. Lima-Fontes, Mário; Costa, Raquel; Rodrigues, Ilda; Soares, Raquel. "Xanthohumol Restores Hepatic Glucolipid Metabolism Balance in Type 1 Diabetic Wistar Rats". Journal of Agricultural and Food Chemistry 65 34 (2017): 7433-7439. http://dx.doi.org/10.1021/acs.jafc.7b02595.
    10.1021/acs.jafc.7b02595
  32. Costa, Raquel; Rodrigues, Ilda; Guardão, Luísa; Rocha-Rodrigues, Sílvia; Silva, Carolina; Magalhães, José; Ferreira-de-Almeida, Manuel; Negrão, Rita; Soares, Raquel. "Xanthohumol and 8-prenylnaringenin ameliorate diabetic-related metabolic dysfunctions in mice". The Journal of Nutritional Biochemistry 45 (2017): 39-47. http://dx.doi.org/10.1016/j.jnutbio.2017.03.006.
    Published • 10.1016/j.jnutbio.2017.03.006
  33. Chora, Inês; Romano, Eloisa; Manetti, Mirko; Mazzotta, Celestina; Costa, Raquel; Machado, Vera; Cortez, Alice; et al. "Evidence for a Derangement of the Microvascular System in Patients with a Very Early Diagnosis of Systemic Sclerosis". The Journal of Rheumatology 44 8 (2017): 1190-1197. http://dx.doi.org/10.3899/jrheum.160791.
    Published • 10.3899/jrheum.160791
  34. Nogueira-Ferreira, Rita; Ferreira-Pinto, Manuel J.; Silva, Ana Filipa; Vitorino, Rui; Justino, Joana; Costa, Raquel; Moreira-Gonçalves, Daniel; et al. "HMGB1 down-regulation mediates terameprocol vascular anti-proliferative effect in experimental pulmonary hypertension". Journal of Cellular Physiology 232 11 (2017): 3128-3138. http://dx.doi.org/10.1002/jcp.25763.
    Published • 10.1002/jcp.25763
  35. Costa, Raquel; Rodrigues, Ilda; Guardão, Luísa; Lima, Joana Quelhas; Sousa, Emília; Soares, Raquel; Negrão, Rita. "Modulation of VEGF signaling in a mouse model of diabetes by xanthohumol and 8-prenylnaringenin: Unveiling the angiogenic paradox and metabolism interplay". Molecular Nutrition & Food Research 61 4 (2017): 1600488. http://dx.doi.org/10.1002/mnfr.201600488.
    Published • 10.1002/mnfr.201600488
  36. Moeenfard, Marzieh; Cortez, Alice; Machado, Vera; Costa, Raquel; Luís, Carla; Coelho, Pedro; Soares, Raquel; et al. "Anti-Angiogenic Properties of Cafestol and Kahweol Palmitate Diterpene Esters". Journal of Cellular Biochemistry 117 12 (2016): 2748-2756. http://dx.doi.org/10.1002/jcb.25573.
    Published • 10.1002/jcb.25573
  37. Sousa, M.; Machado, V.; Costa, R.; Figueira, M.E.; Sepodes, B.; Barata, P.; Ribeiro, L.; Soares, R.. "Red Raspberry Phenols Inhibit Angiogenesis: A Morphological and Subcellular Analysis Upon Human Endothelial Cells". Journal of Cellular Biochemistry 117 7 (2016): 1604-1612. http://dx.doi.org/10.1002/jcb.25452.
    Published • 10.1002/jcb.25452
  38. Machado, Vera A.; Peixoto, Daniela; Costa, Raquel; Froufe, Hugo J.C.; Calhelha, Ricardo C.; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Soares, Raquel; Queiroz, Maria-João R.P.. "Synthesis, antiangiogenesis evaluation and molecular docking studies of 1-aryl-3-[(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas: Discovery of a new substitution pattern for type II VEGFR-2 Tyr kinase inhibitors". Bioorganic & Medicinal Chemistry 23 19 (2015): 6497-6509. http://dx.doi.org/10.1016/j.bmc.2015.08.010.
    Published • 10.1016/j.bmc.2015.08.010
  39. Castela, A.; Gomes, P.; Domingues, V.; Paíga, P.; Costa, R.; Vendeira, P.; Costa, C.. "Disfunção erétil na diabetes – avaliação de alterações moleculares induzidas pelo stresse oxidativo". Acta Urológica Portuguesa 32 1 (2015): 20-27. http://dx.doi.org/10.1016/j.acup.2015.01.002.
    10.1016/j.acup.2015.01.002
  40. Castela, Angela; Gomes, Pedro; Domingues, Valentina F.; Paíga, Paula; Costa, Raquel; Vendeira, Pedro; Costa, Carla. "Role of oxidative stress-induced systemic and cavernosal molecular alterations in the progression of diabetic erectile dysfunction". Journal of Diabetes 7 3 (2014): 393-401. http://dx.doi.org/10.1111/1753-0407.12181.
    Published • 10.1111/1753-0407.12181
  41. Lopes, Flávia Cristine Mascia; Ferreira, Regiane; Albuquerque, Dulcinéia Martins; Silveira, Angélica A. Antoniellis; Costa, Raquel; Soares, Raquel; Costa, Fernando Ferreira; Conran, Nicola. "In vitro and in vivo anti-angiogenic effects of hydroxyurea". Microvascular Research 94 (2014): 106-113. http://dx.doi.org/10.1016/j.mvr.2014.05.009.
    Published • 10.1016/j.mvr.2014.05.009
  42. Costa, Raquel; Negrão, Rita; Valente, Inês; Castela, Ângela; Duarte, Delfim; Guardão, Luísa; Magalhães, Paulo J.; et al. "Xanthohumol Modulates Inflammation, Oxidative Stress, and Angiogenesis in Type 1 Diabetic Rat Skin Wound Healing". Journal of Natural Products 76 11 (2013): 2047-2053. http://dx.doi.org/10.1021/np4002898.
    Published • 10.1021/np4002898
  43. Negrão, Rita; Duarte, Delfim; Costa, Raquel; Soares, Raquel. "Isoxanthohumol modulates angiogenesis and inflammation via vascular endothelial growth factor receptor, tumor necrosis factor alpha and nuclear factor kappa B pathways". BioFactors 39 6 (2013): 608-622. http://dx.doi.org/10.1002/biof.1122.
    Published • 10.1002/biof.1122
  44. Ramalho, Renata; Almeida, Joana; Fernandes, Rubén; Costa, Raquel; Pirraco, Ana; Guardão, Luísa; Delgado, Luís; Moreira, André; Soares, Raquel. "Neurokinin-1 receptor, a new modulator of lymphangiogenesis in obese-asthma phenotype". Life Sciences 93 4 (2013): 169-177. http://dx.doi.org/10.1016/j.lfs.2013.06.010.
    Published • 10.1016/j.lfs.2013.06.010
  45. Duarte, D.; Taveira-Gomes, T.; Sokhatska, O.; Palmares, C.; Costa, R.; Negrão, R.; Guimarães, J. T.; et al. "Increased circulating platelet microparticles as a potential biomarker in asthma". Allergy 68 8 (2013): 1073-1075. http://dx.doi.org/10.1111/all.12190.
    Published • 10.1111/all.12190
  46. Negrão, Rita; Costa, Raquel; Duarte, Delfim; Gomes, Tiago Taveira; Azevedo, Isabel; Soares, Raquel. "Different effects of catechin on angiogenesis and inflammation depending on VEGF levels". The Journal of Nutritional Biochemistry 24 2 (2013): 435-444. http://dx.doi.org/10.1016/j.jnutbio.2011.12.011.
    Published • 10.1016/j.jnutbio.2011.12.011
  47. Soares, Pedro; Costa, Raquel; Froufe, Hugo J. C.; Calhelha, Ricardo C.; Peixoto, Daniela; Ferreira, Isabel C. F. R.; Abreu, Rui M. V.; Soares, Raquel; Queiroz, Maria-João R. P.. "1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modelling Studies". BioMed Research International 2013 (2013): 1-9. http://dx.doi.org/10.1155/2013/154856.
    Published • 10.1155/2013/154856
  48. Costa, R.; Ribeiro, C.; Lopes, A. C.; Martins, P.; Sencadas, V.; Soares, R.; Lanceros-Mendez, S.. "Osteoblast, fibroblast and in vivo biological response to poly(vinylidene fluoride) based composite materials". Journal of Materials Science: Materials in Medicine 24 2 (2013): 395-403. http://dx.doi.org/10.1007/s10856-012-4808-y.
    Published • 10.1007/s10856-012-4808-y
  49. Ramalho, R.; Almeida, J.; Beltrão, M.; Pirraco, A.; Costa, R.; Sokhatska, O.; Guardão, L.; et al. "Substance P antagonist improves both obesity and asthma in a mouse model". Allergy 68 1 (2012): 48-54. http://dx.doi.org/10.1111/all.12052.
    Published • 10.1111/all.12052
  50. Ramalho, Renata; Almeida, Joana; Beltrão, Marília; Pirraco, Ana; Costa, Raquel; Sokhatska, Oksana; Guardão, Luísa; et al. "Neurogenic inflammation in allergen-challenged obese mice: a missing link in the obesity-asthma association?". Experimental Lung Research 38 6 (2012): 316-324. http://dx.doi.org/10.3109/01902148.2012.699589.
    Published • 10.3109/01902148.2012.699589
  51. Negrão, Rita; Costa, Raquel; Duarte, Delfim; Gomes, Tiago Taveira; Coelho, Pedro; Guimarães, João T.; Guardão, Luísa; Azevedo, Isabel; Soares, Raquel. "Xanthohumol-supplemented beer modulates angiogenesis and inflammation in a skin wound healing model. Involvement of local adipocytes". Journal of Cellular Biochemistry 113 1 (2012): 100-109. http://dx.doi.org/10.1002/jcb.23332.
    Published • 10.1002/jcb.23332
  52. Carneiro, Ângela M.; Costa, Raquel; Falcão, Manuel S.; Barthelmes, Daniel; Mendonça, Luis S.; Fonseca, Sofia L.; Gonçalves, Rita; et al. "Vascular endothelial growth factor plasma levels before and after treatment of neovascular age-related macular degeneration with bevacizumab or ranibizumab". Acta Ophthalmologica 90 1 (2012): e25-e30. http://dx.doi.org/10.1111/j.1755-3768.2011.02240.x.
    Published • 10.1111/j.1755-3768.2011.02240.x
  53. Ramalho, R.; Almeida, J.; Beltr~ao, M.; Pirraco, A.; Costa, R.; Sokhatska, O.; Guard~ao, L.; et al. "Erratum: Neurogenic inflammation in allergen-challenged obese mice: A missing link in the obesity-asthma association? (Experimental Lung Research 38:6 (316-324))". Experimental Lung Research 38 7 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84865145043&partnerID=MN8TOARS.
    10.3109/01902148.2012.712796
  54. Negrão, Rita; Duarte, Delfim; Costa, Raquel; Soares, Raquel. "Could platelet-accumulating polyphenols prevent tumour metastasis?". Nature Reviews Cancer 11 9 (2011): 685-685. http://dx.doi.org/10.1038/nrc3004-c1.
    Published • 10.1038/nrc3004-c1
  55. Ramos, Reinaldo; Silva, João Pedro; Rodrigues, Ana Cristina; Costa, Raquel; Guardão, Luísa; Schmitt, Fernando; Soares, Raquel; et al. "Wound healing activity of the human antimicrobial peptide LL37". Peptides 32 7 (2011): 1469-1476. http://dx.doi.org/10.1016/j.peptides.2011.06.005.
    Published • 10.1016/j.peptides.2011.06.005
  56. Negrão, Rita; Costa, Raquel; Duarte, Delfim; Taveira Gomes, Tiago; Mendanha, Mário; Moura, Liane; Vasques, Luísa; Azevedo, Isabel; Soares, Raquel. "Angiogenesis and Inflammation Signaling Are Targets of Beer Polyphenols on Vascular Cells". Journal of Cellular Biochemistry 111 5 (2010): 1270-1279. http://dx.doi.org/10.1002/jcb.22850.
    Published • 10.1002/jcb.22850
  57. Andrade, Fábia K.; Costa, Raquel; Domingues, Lucília; Soares, Raquel; Gama, Miguel. "Improving bacterial cellulose for blood vessel replacement: Functionalization with a chimeric protein containing a cellulose-binding module and an adhesion peptide". Acta Biomaterialia 6 10 (2010): 4034-4041. http://dx.doi.org/10.1016/j.actbio.2010.04.023.
    Published • 10.1016/j.actbio.2010.04.023
  58. Pirraco, Ana; Coelho, Pedro; Rocha, Ana; Costa, Raquel; Vasques, Luísa; Soares, Raquel. "Imatinib targets PDGF signaling in melanoma and host smooth muscle neighboring cells". Journal of Cellular Biochemistry 111 2 (2010): 433-441. http://dx.doi.org/10.1002/jcb.22725.
    Published • 10.1002/jcb.22725
  59. Costa, Raquel; Carneiro, ÿngela; Rocha, Ana; Pirraco, Ana; Falcão, Manuel; Vasques, Luísa; Soares, Raquel. "Bevacizumab and ranibizumab on microvascular endothelial cells: A comparative study". Journal of Cellular Biochemistry 108 6 (2009): 1410-1417. http://dx.doi.org/10.1002/jcb.22378.
    Published • 10.1002/jcb.22378
Magazine article
  1. Costa, Raquel; Silva, SB; Rodrigues, Ilda; Soares, Raquel; Leite-Oliveira, Ana. "Efeito de um hidrogel de sericina na cicatrização de feridas crónicas num modelo animal de Diabetes Tipo 2", Revista Portuguesa de Diabetes, 2020
  2. Campos Silva, Carolina; Rodrigues, Ilda; Soares, Raquel; Costa, Raquel. "A Metformina inibe a Angiogénse e a formação de colagénio em HMEC-1 em condições de hiperglicemia", Revista Portuguesa de Diabetes, 2020
  3. Silva, Carolina; Soares, Raquel; Costa, Raquel; Rodrigues, Ilda. "Efeito da metformina na formação de estruturas capilares em HMEC-1 expostas à condições de hiperglicemia", Revista Portuguesa de Diabetes, 2019
  4. Campos Silva, Carolina; Rodrigues, Ilda; Andrade, Sara; Soares, Raquel; Costa, Raquel. "Effects of AICAR, Compound C and Metformin administration in metabolic and angiogenic behavior in human vascular endothelial cells", Revista Portuguesa de Diabetes, 2019
  5. Costa, Raquel; Rodrigues, Ilda; Negrão, Rita; Soares, Raquel. "Modulação metabólica e vascular por polifenóis da dieta num modelo animal de diabetes tipo 2", Revista Portuguesa de Diabetes, 2018
  6. Guerra, Ana; Costa, Raquel; Rodrigues, Ilda; Neves, Catarina; Vieira, Hugo; Ferreira, Sílvia; Calhau, Conceição; Pestana, Diogo; Negrão, Rita. "Modulation of VEGF-A and VEGF-B signaling by DDE exposure: implications in metabolic dysfunction", IJUP 2017, 2017
  7. Guerra, Ana; Costa, Raquel; Rodrigues, Ilda; Neves, Catarina; Vieira, Hugo; Ferreira, Silvia; Calhau, Conceição; Pestana, Diogo; Negrão, Rita. "Modulation of VEGF-B signaling by DDE exposure ¿ Effect on fatty acid accumulation", Revista Portuguesa de Diabetes, 2016
  8. Lima-Fontes, Mário; Costa, Raquel; Rodrigues, Ilda; Soares, Raquel. "Xanthohumol restores hepatic glucolipid metabolismo balance in type 1 diabetic Wistar rats", Revista Portuguesa de Diabetes, 2016
  9. Costa, Raquel; Rodrigues, Ilda; Guardão, Luísa; Negrão, Rita; Soares, Raquel. "Polyphenol modulate type 2 diabetes: Relevance to angiogenic paradox", Revista Portuguesa de Diabetes, 2016
  10. Luís, Carla; Costa, Raquel; Castela, Angela; Rodrigues, Ilda; Coelho, Pedro; Reis, Celso; Soares, Raquel. "Relação entre a galactina-3 e produtos de glicação avançada (AGE): O caminho para melhorar a saúde cardíaca em diabetes mellitus tipo 2", Revista Portuguesa de Diabetes, 2015
  11. Costa, Raquel; Almeida, Raquel; Rodrigues, Ilda; Guardão, Luísa; Guimarães, João Tiago; Negrão, Rita; Soares, Raquel. "Vascular impairment associated with diabetic condition", Revista Portuguesa de Diabetes, 2013
Thesis / Dissertation
  1. Costa, Raquel. "Polyphenols in diabetic vascular complications: from mechanisms to identification of therapeutic targets". PhD, Faculty of Medicine, University of Porto, 2017. https://hdl.handle.net/10216/105160.
  2. Costa, Raquel. "Modulação in vivo da angiogénese, inflamação e stresse oxidativo em situações fisiopatológicas após consumo de cerveja enriquecida com xanto-humol". Master, Faculty of Sciences, University of Porto, 2011. https://sigarra.up.pt/fcup/pt/teses.tese?p_aluno_id=102812&p_processo=17720&p_lang=0.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/03/02 Self-assembled silk fibroin aerogel particles for wound healing 2º Encontro Ibérico de Fluidos Supercríticos
University of Coimbra (Coimbra, Portugal)
2021 Silk fibroin aerogel particles via the emulsion-gelation method for the treatment of chronic wounds Advanced technologies for the processing and characterization of nanostructured materials
(Cracow, Poland)
2021 Silk fibroin aerogel particles for chronic wound healing Athens Conference on Advances in Chemistry (ACAC 2021)
(online, Greece)
2021 Structure and properties of silk fibroin aerogel particles prepared by emulsion-gelation followed by supercritical CO2 for wound healing 31st Conference of the European Society for Biomaterials
(Porto Area, Portugal, Portugal)
2021 In situ antioxidant activity of an enzymatically crosslinked sericin hydrogel for healing of chronic wounds 31st Conference of the European Society for Biomaterials
(Porto, Portugal)
2021 Bio-aerogéis: materiais nanoestruturados promissores na gestão de fluidos, cicatrização e regeneração de feridas APTFeridas 2.1: [DES]CONSTRUIR O CONHECIMENTO congress
(Porto, Portugal)
2020/10 Invited speaker - Polifenóis como moduladores angiogénicos e metabólicos na Diabetes tipo 2 HIB
I Congresso Internacional Digital de Nutrição (Brazil)
2020/10 Invited speaker - Antioxidantes na alimentação: bons ou maus aliados World Food day 2020
Universidade de Coimbra (Portugal)
2020/10 Invited Speaker - Polyphenol consumption for disease prevention World Food Day 2020
Universidade de Coimbra (Portugal)
2019/09 Diet-derived Xanthohumol ameliorate diabetic-related dysfunctions in mice 2nd Conference on Innovations in Food Science & Human Nutrition
Innovinc (London, United Kingdom)
2019/06 Invited speaker - Polyphenols as potential nutraceuticals in type 2 diabetes 4th International Congress of CiiEM on “Health, well-being and ageing in the XXI Century”
Egas Moniz University Campus in Caparica (Almada, Portugal)
2019 Modulation of Human Endothelial Cell Angiogenic Processes by Platelets from Patients with Stickle Cell Disease 61 st ASH Annual Meeting & Exposition
(Orlando, United States)
2018 “A hemólise aguda induz processos inflamatórios e angiogénicos in vivo” Congresso Brasileiro de Hematologia, Hemoterapia e Terapia Celular
HEMO, São Paulo, Brasil (Campinas, Brazil)
2018 Invited speaker - Diabetes e Polifenóis Seminar in the master of clinical biochemistry and metabolomics
Escola Superior de Saúde, Porto, Portugal (Porto, Portugal)
2018 Invited speaker - Polifenóis e diabetes Seminar in the pos-graduation in phytotherapy and pharmacotechnics
Universidade Fernando Pessoa, Porto, Portugal (Porto, Portugal)
2017 Invited speaker - Obesidade e Polifenóis Congresso Português de Obesidade
Sociedade Portuguesa para o Estudo da Obesidade (Aveiro, Portugal)
2016/02 Modulation of VEGF-B signaling in obesity by DDE exposure 8.º Simpósio em Metabolismo, Porto, Portugal
Faculty of Medicine, University of Porto (Porto, Portugal)
2016/02 “Xanthohumol restores hepatic glucolipid metabolism balance in type 1 diabetic Wistar rats” 8.º Simpósio em Metabolismo, Porto, Portugal
University of Porto (Porto, Portugal)
2016 “Red raspberry phenols inhibit angiogenesis. Eat to starve cancer and avoid slow damage accumulation diseases?” 9th meeting of young researchers at UP (IJUP), Porto, Portugal
University of Porto (Porto Area, Portugal, Portugal)
2015 “Efeito dos polifenóis nas complicações vasculares e metabólicas associadas à diabetes mellitus tipo 2” VII Simpósio em Metabolismo, Porto, Portugal
Faculty of Medicine, University of Porto (Porto, Portugal)
2014 “A inibição da survivina reverte a remodelação cardíaca e pulmonar na hipertensão arterial pulmonary induzida pela monocrotalina” XXXV Congresso Português de Cardiologia
Sociedade Portuguesa de Cardiologia (Albufeira, Portugal)
2013 “Survivin role in pulmonary arterial hypertension” 6th IJUP
University of Porto (Porto, Portugal)
2013 “New 1,3-diarylurea derivatives of thieno[3,2-d]pyrimidine ethers as VEGFR2 inhibitors: synthesis, docking studies and biological evaluation” Porto Cancer Meeting
(Porto, Portugal)
2012 “Proangiogenic effects of plasma from sickle cell disease patients and antiangiogenic effects of hydroxyurea: Evaluation of invasion and proliferation of Human Endothelial Cells and effects of hydroxyurea in a mouse Matrigel plug neovascularization assay” 54th ASH Annual Meeting, Atlanta, Georgia.
(Atlanta, Georgia)
2012 “Synthesis, docking, enzymatic and cellular assays of thieno[3,2-b]pyridine-thioether-1,3-diarylureas as VEGFR2 inhibitors” 3º Encontro Nacional de Química Terapêutica and 1st Portuguese-Spanish-Brazilian Meeting on Medicinal Chemistry
(Aveiro, Portugal)
2012 “Survivin role in pulmonar arterial hypertension” VII Yes Meeting
University of Porto (Porto, Portugal)
2012 “Isoxanthohumol inhibits in vivo vascular proliferation and stabilization” IJUP
(Porto, Portugal)
2011 “Substância P e o fenótipo obesidade-asma” 15º Congresso Português de obesidade.
(Coimbra, Portugal)
2011 “Defective retinal angiogenesis in isoxanthohumol-treated mice” IJUP
(Porto, Portugal)
2011 “Protein structural alterations in diabetic cavernosal tissue – their role in erectile dysfunction progression” 14th ESSM Congress
(Milan, Italy)
2010 “Efeito de polifenóis presentes na cerveja na modulação da angiogénese e da inflamação” 7as Jornadas iBeSa
(Porto, Portugal)
2010 “Modulation of angiogenesis and inflammation by beer-derived polyphenols- In vivo effects” IJUP
(Porto, Portugal)
2008 “Níveis de VEGF sérico em doentes submetidos a terapia intravítrea com Bevacizumab” Jornadas de Investigação do 51º Congresso português de oftalmologia
(Porto, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022/09 - Current Bioactivity and regenerative potential of functionalized Polycaprolactone-based skin dressings for diabetic wounds management
Supervisor
 Metabolismo ¿ Biopatologia e Experimentação (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2021/09 - Current LessDiSRUPTIVE - Less DISRUPTIVE technologies for processing biological tissue into preserved and highly functional matrices for wound healing and regeneration
Co-supervisor
 Biotecnologia (PhD)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

University of Maastrich, MERLN Institute, Netherlands
2020/10/01 - Current AEROREGEN: Natural-based AEROgel formulations towards healing and REGENeration of diabetic wounds
Co-supervisor of Beatriz Gonçalves Bernardes
 Biotecnologia (PhD)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

Universidade de Santiago de Compostela, Spain
2020/01 - Current The paradoxal role between diabetes and prostatic cancer
Co-supervisor
 Bioquímica em Saúde (Master)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2020/09/01 - 2023/12/30 Evaluation of mesenchymal stem cells influence on human diabetic endothelial cardiac cells
Co-supervisor of Raquel Segura Gonçalves
 Biologia Celular e Molecular (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2022/09 - 2023/11 Comparing Safinamide and Rasagiline therapeutic effects: seeking for a disease-modifying strategy for Parkinson’s Disease
Co-supervisor
 Metabolismo Biopatologia e Experimentação (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2018/09 - 2019/07 Compostos antioxidantes e bioativos em extratos de açaí
Co-supervisor
 Biochemistry (Degree)
Faculty of Sciences, University of Porto, Portugal

Abel Salazar Institute, University of Porto, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019/10 - 2019/10 11º Simpósio em Metabolismo (2019/10 - 2019/10)
Symposium (Member of the Organising Committee)
 Faculty of Medicine, University of Porto, Portugal
2018/10 - 2018/10 10º Simpósio em Metabolismo (2018/10 - 2018/10)
Symposium (Member of the Organising Committee)
 Faculty of Medicine, University of Porto, Portugal
2017/10 - 2017/10 9º Simpósio em Metabolismo (2017/10 - 2017/10)
Symposium (Member of the Organising Committee)
 Faculty of Medicine, University of Porto, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/03 - Current Poster presentation - Frantz Gojon, André Sousa, Ana Catarina Rocha, Cláudia Sousa-Mendes, Ilda Rodrigues, Raquel Soares, Ruben Fernandes, Raquel Costa (2023) “Influência de membranas de policaprolactona na remodelação celular de um modelo animal de úlceras de pé diabético” 19º Congresso da Sociedade Portuguesa de Diabetologia, Vilamoura, Portugal
Congress
 19º Congresso da Sociedade Portuguesa de Diabetologia
Sociedade Portuguesa de Diabetologia, Portugal
2022/03 - 2022/03 Poster presentation - Costa R, Batista-Silva S, Bernardes B, Rodrigues I, Teixeira-Pinto M, Pintado M, Soares R and Leite-Oliveira A "Efeitos benéficos de um hidrogel de sericina na regeneração e cicatrização de feridas crónicas em animais com diabetes tipo 2"
Congress
 18º Congresso Nacional de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2021/05 - 2021/05 Poster presentation - André Sousa, Catarina Teixeira, Inês Santos, Frantz Gojon, André Coelho, Joana Rigor, Daniela Mendes, Raquel Soares, Raquel Costa, Pilar Baylina, Rúben Fernandes "Biopotential from antidiabetic drugs exploiting therapeutical approaches for prostate cancer"
Meeting
 14th meeting of young researchers at UP (IJUP), Porto, Portugal
IJUP, Portugal
2021/05 - 2021/05 Poster presentation - Raquel Gonçalves, Raquel Costa, Pedro Coelho, Raquel Soares and Andreia Gomes "Angiogenic modulation by umbilical cord sérum and mesenchymal stem cells secretome"
Meeting
 14th meeting of young researchers at UP (IJUP), Porto, Portugal
IJUP, Portugal
2021/03 - 2021/03 Poster presentation - Sousa A, Lopes S, Luis C, Guedes C, Teixeira C, Rigor J, Mendes-Martins D, Costa R, Duarte F, Soares R, Baylina P and Fernandes R "Avaliação do potencial anti tumoral de fármacos antidiabéticos em cancro de próstata"
Congress
 17º Congresso Nacional de Diabetes
2021/03 - 2021/03 Poster presentation Sousa A, Luís C, Lopes S, Guedes C, Teixeira C, Rigor J, Mendes-Martins D, Costa R, Baylina P and Fernandes R "Efeito da testosterona e estradiol no paradoxo diabetes/cancro de próstata"
Congress
 17º Congresso Nacional de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2021/03 - 2021/03 Poster presentation Costa R., Silva S.B., Rodrigues I., Soares R. and Leite-Oliveira A. “Aplicação de um hidrogel de sericina em feridas crónicas de animais com diabetes tipo 2”
Congress
 17º Congresso Nacional de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2021 - 2021 Poster presentation - A Sousa, C Luís, D Martins-Mendes, J Rigor, S Soares, M Alves, R Soares, P Baylina, R Costa, R Fernandes "Does diabetic secretome encloses the key to fight prostate cancer?"
Meeting
 AIMS meeting
Faculty of Medicine, University of Lisbon, Portugal
2021 - 2021 Poster presentation - A Sousa, C Teixeira, I Santos, F Gojon, A Coelho, J Rigor, D Mendes, R Soares, R Costa, P Baylina, R Fernandes “Biopotential from antidiabetic drugs - exploiting therapeutical approaches for prostate cancer”
Meeting
 27th Porto Cancer Meeting
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
2021 - 2021 Poster presentation - A Sousa, F Leite, R Soares, A Gomes and R Costa “Umbilical cord mesenchymal stem cells secretome suppresses prostate cancer through the activation of p53 pathway” 3º Encontro Nacional de Jovens Investigadores em Oncologia, Porto, Portugal.
Meeting
 3º Encontro Nacional de Jovens Investigadores em Oncologia
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2021 - 2021 Poster presentation - André Sousa, Raquel Soares, Rúben Fernandes, Raquel Costa* and Andreia Gomes* “Umbilical cord blood serum potential anti-tumor effects in prostate cancer”
Conference
 ASPIC-ASEICA international meeting
2021 - 2021 Poster presentation - A Sousa, S Soares, M Alves, R Soares, P Baylina, R Costa and R Fernandes “PCa paradox - biochemical and metabolic state between prostate cancer and diabetes mellitus type 2”
Meeting
 ASPIC-ASEICA international meeting
2021 - 2021 Poster presentation - A Gomes, R Gonçalves, L Leite, R Soares and R Costa* “Umbilical Cord Serum and Mesenchymal Stem Cell Secretome Effects in Angiogenesis Under Hyperglycemic environment”.
Meeting
 Cell Bio Virtual 2021-An Online ASCB|EMBO Meeting
2021 - 2021 Poster presentation - R Costa, A Sousa, F Leite, R Soares and A Gomes “Umbilical Cord Mesenchymal Stem Cell Secretome Inhibitory Effects in Prostate Cancer Cell Lines”. Cell Bio Virtual 2021
Meeting
 Cell Bio Virtual 2021-An Online ASCB|EMBO Meeting
2021 - 2021 Poster presentation - Raquel Costa, André Sousa, Raquel Soares and Andreia Gomes “Prostate cancer cell lines inhibition by umbilical cord blood serum”
Conference
 Cord Blood Connect
Cord Blood Association, United States
2020/11 - 2020/11 Poster presentation - Azevedo D, Carvalho D, Barata P, Guido L, Soares R and Costa R* "Antioxidant and antiangiogenic properties of açaí berries"
Conference
 IberPhenol
Universidade de Coimbra, Portugal
2020/03 - 2020/03 Poster presentation - Costa R., Silva S.B., Rodrigues I., Soares R. and Leite-Oliveira A. "Efeito de um hidrogel de sericina na cicatrização de feridas crónicas num modelo animal de diabetes tipo 2"
Congress
 16º Congresso Nacional de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2020/03 - 2020/03 Poster presentation - Silva C., Rodrigues I., Soares R and Costa R A metformina inibe a angiogénese e a formação de colagénio em HMEC-1 em condições de hiperglicemia
Congress
 16º Congresso Nacional de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2020/03 - 2020/03 Poster presentation - Sousa A., Luís C., Rigor J., Barbosa J. P., Martins D. M., Costa R., Fernandes R. "Prostate cancer cell PC3 behavior under a simulated type 2 diabetic microenvironment"
Congress
 16º Congresso Nacional de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2019/09 - 2019/09 Poster presentation - Azevedo D, Carvalho D, Guido L, Soares R and Costa R “Anti-angiogenic potential of açaí-derived polyphenols: an in vitro approach”
Conference
 2nd Conference on Innovations in Food Science & Human Nutrition
Innovinc, United States
2019/03 - 2019/03 Poster presentation - Silva CC, Rodrigues, Andrade S, Soares R and Costa R “Efeito da metformina na formação de capilares em HMEC-1 expostas a elevada concentração de glicose”
Congress
 15º Congresso da Sociedade Portuguesa de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2019 - 2019 Poster presentation - Daniela Azevedo, Raquel Costa, Luís Guido, Raquel Soares and Daniel Carvalho “Screening of phenolic compounds in açaí and evaluation of its anti-angiogenic activity”
Congress
 XXEuroFoodChem
2019 - 2019 Poster presentation - Costa L, Tamagnini P, Soares R, Costa R and Ramos R “Development of wound dressings based on cyanobacterial extracellular heteropolysaccharides”
Conference
 iMED Conference 11.0
2018/10 - 2018/10 Poster presentation - Silva CC, Rodrigues, Andrade S, Soares R and Costa R “Effects of AICAR, Compound C and Metformin administration in metabolic and angiogenic behaviour in human vascular endothelial cells”
Symposium
 10º Simpósio em Metabolismo
Faculty of Medicine, University of Porto, Portugal
2018/03 - 2018/03 Poster presentation - Costa R, Rodrigues I, Negrão R and Soares R "Modulação metabólica e vascular por polifenóis da dieta num modelo animal de diabetes tipo 2"
Congress
 14º Congresso Português de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2018 - 2018 Poster presentation - Gotardo E., Chweih H, Brito P, Leonardo F, Costa R, Soares R, Costa F and Conran N "Acute Hemolysis induces pro-angiogenic molecule production and neovascularization in vivo"
Meeting
 60th ASH Annual Meeting and Exposition, San Diego, CA
2018 - 2018 Poster presentation - Fabris F, Leonardo F, Soares R, Costa R, Saad S, Costa F and Conran N “Efeitos das plaquetas de pacientes com anemia falciforme em processos angiogénicos de células endoteliais”
Congress
 Congresso Brasileiro de Hematologia, Hemoterapia e Terapia Celular - HEMO, São Paulo, Brasil
Hemocentro - UNICAMP, Brazil
2018 - 2018 Poster presentation - AC Guerra, R Costa, I Rodrigues, C Neves, H Veiga, S Ferreira, SI Sousa, VF Domingues, C Calhau, D Pestana e R Negrão “Modulation of VEGFB signaling by DDE exposure in obesity”
Congress
 25º Congresso Europeu de Obesidade
2017 - 2017 Poster presentation - Guerra AC, Costa R, Rodrigues I, Neves C, Vieira H, Ferreira S, Sousa SI, Domingues VF, Calhau C, Pestana D and Negrão R Modulation of VEGF-A and VEGF-B signaling by DDE exposure: implications in metabolic dysfunction
Meeting
 10th meeting of young researchers at UP (IJUP), Porto, Portugal
Universidade do Porto, Portugal
2016 - 2016 Poster presentation - Costa R, Rodrigues I, Guardão L, Negrão R and Soares R “Dietary polyphenols modulate angiogenic paradox in type 2 diabetic animals”
Meeting
 5th Annual Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016 - 2016 Poster presentation - Costa R, Rodrigues I, Guardão L, Negrão R and Soares R “Polyphenols as diabetic modulators: Relevance to angiogenic paradox”
Symposium
 Simpósio em Metabolismo
Faculty of Medicine, University of Porto, Portugal
2016 - 2016 Poster presentation - Lima-Fontes M, Costa R, Rodrigues I and Soares R “Xanthohumol restores hepatic glucolipid metabolism balance in type 1 diabetic Wistar rats”
Meeting
 11st Yes Meeting
Faculty of Medicine, University of Porto, Portugal
2016 - 2016 Poster presentation - Guerra AC, Costa R, Rodrigues I, Neves C, Vieira H, Ferreira S, Sousa SI, Domingues VF, Calhau C, Pestana D and Negrão R “Modulation of VEGF-B signaling in obesity by DDE exposure”
Meeting
 5th i3S Annual Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016 - 2016 Poster presentation - Costa C, Castela A, Gomes P, Ribeiro AR, Costa R, Guardão L, Leite L and Vendeira P “Unveiling the role of vasculogenesis in diabetic erectile dysfunction using a bone marrow transplantation model: preliminary results”
Congress
 18th Congress of the European Society of Sexual Medicine
European Society of Sexual Medicine, Spain
2016 - 2016 Poster presentation - Chora I, Romano E, Mazzotta C, Manetti M, Costa R, Machado V, Cortez A, Guiducci S, Soares R and Matucci-Cerinic M “Evidence for a derangement of the microvascular system in patients with a very early diagnosis of systemic sclerosis”
Congress
 4th Systemic Sclerosis World Congress
2016 - 2016 Poster presentation - Costa R, Negrão R and Soares R “O consumo de polifenóis modula as alterações vasculares na diabetes mellitus tipo 2”
Congress
 12º Congresso Português de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2016 - 2016 Poster presentation - Costa R, Negrão R and Soares R “Polyphenol consumption modulates angiogenic pathways in diabetes mellitus type 2”
Meeting
 5º Encontro de doutorandos
Faculty of Medicine, University of Porto, Portugal
2016 - 2016 Poster presentation R. Costa, I. Rodrigues, L. Guardão, R. Negrão and R. Soares “Dietary polyphenols modulate angiogenic paradox in type 2 diabetic animals”
Meeting
 5th i3S Annual Meeting
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
2016 - 2016 Poster presentation - Costa R, Rodrigues I, Guardão L, Negrão R and Soares R “Polyphenols as diabetic modulators: Relevance to angiogenic paradox”
Symposium
 8.º Simpósio em Metabolismo, Porto, Portugal
Faculty of Medicine, University of Porto, Portugal
2016 - 2016 Poster presentation - A.C. Guerra, R. Costa, I. Rodrigues, C. Neves, H. Vieira, S. Ferreira, S.I. Sousa, V.F. Domingues, C. Calhau, D. Pestana and R. Negrão “Modulation of VEGF-B signaling in obesity by DDE exposure”
Meeting
 5th i3S Annual Meeting
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
2016 - 2016 Poster presentation - Costa C, Castela A, Gomes P, Ribeiro AR, Costa R, Guardão L, Leite L and Vendeira P “Unveiling the role of vasculogenesis in diabetic erectile dysfunction using a bone marrow transplantation model: preliminary results”
Congress
 18th Congress of the European Society of Sexual Medicine
2016 - 2016 Poster presentation - I. Chora, E. Romano, C. Mazzotta, M. Manetti, R. Costa, V. Machado, A. Cortez, S. Guiducci, R. Soares, M. Matucci-Cerinic “Evidence for a derangement of the microvascular system in patients with a very early diagnosis of systemic sclerosis”
Congress
 4th Systemic Sclerosis World Congress
2016 - 2016 Poster presentation - Costa R, Negrão R, Soares R “O consumo de polifenóis modula as alterações vasculares na diabetes mellitus tipo 2”
Congress
 12º Congresso Português de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2016 - 2016 Poster presentation - Costa R, Negrão R, Soares R “Polyphenol consumption modulates angiogenic pathways in diabetes mellitus type 2”
Meeting
 5º Encontro de doutorandos
Faculty of Medicine, University of Porto, Portugal
2015 - 2015 Poster presentation - Costa R, Negrão R and Soares R “Xanthohumol and 8-Prenylnaringenin modulate angiogenic and metabolic pathways in diabetic animals”
Conference
 7th International Conference on Polyphenols and Health (ICPH)
2015 - 2015 Poster presentation - Luís C, Costa R, Rodrigues I, Gomes J, Reis C, Soares R “Relação entre galactina-3 e produtos de glicação avançada (AGE): O caminho para melhorar a saúde cardíaca em diabetes mellitus tipo 2”
Symposium
 VII Simpósio em Metabolismo, Porto, Portugal
Faculty of Medicine, University of Porto, Portugal
2015 - 2015 Poster presentation - Fontes M, Costa R, Soares R “Beer polyphenols can modulate angiogenic and metabolic pathways in T2 diabetes”
Meeting
 X Yes Meeting, Porto, Portugal.
Faculty of Medicine, University of Porto, Portugal
2015 - 2015 Poster presentation - C. Luís, R. Costa, A. Castela, I. Rodrigues, P. Coelho, J. Gomes, C. Reis, R. Soares “Expression of Galectin-3 and Nitrotyrosine in a Type-2 Diabetic Mellitus mouse model”
Meeting
 VIII IJUP, Porto, Portugal
University of Porto, Portugal
2015 - 2015 Poster presentation - Costa R, Negrão R, Soares R “Efeito dos polifenóis nas complicações vasculares associadas à diabetes mellitus tipo 2”
Congress
 Congresso da Sociedade Portuguesa de Diabetologia
Sociedade Portuguesa de Diabetologia, Portugal
2015 - 2015 Poster presentation - Luís C, Costa R, Rodrigues I, Silva C, Coelho P, Gomes J, Guerreiro S, Reis C, Soares R “Efeito dos polifenóis na expressão da galactina-3 num modelo de rato diabético”
Meeting
 Reunião anual da Sociedade Portuguesa de Diabetologia. Tomar, Portugal
Sociedade Portuguesa de Diabetologia, Portugal
2014 - 2014 Poster presentation - Costa R, Costa-Almeida R, Silva, A, Rodrigues I, Guardão L, Guimarães JT, Negrão R, Soares R “Complicações vasculares associadas à diabetes mellitus tipo 2”
Congress
 11º Congresso Português de Diabetes, Vilamoura, Portugal
Sociedade Portuguesa de Diabetologia, Portugal
2014 - 2014 Poster presentation - Vera A. Machado, Daniela Peixoto, Raquel Costa, Ricardo C. Calhelha, Rui M.V. Abreu, Isabel C. F. R. Ferreira, Raquel Soares, Maria-João R .P. Queiroz “Synthesis Molecular Docking and Biological Evaluation of new 1-Aryl-3-[3-(thieno[3,2-b]pyridin-7-ylthio)phenylureas as Potent Type II VEGFR-2 Tyrosine Kinase Inhibitors”
Symposium
 International Symposium of Medicinal Chemistry, Lisbon, Portugal.
2014 - 2014 Poster presentation - Vera A. Machado, Raquel Costa, Daniela Peixoto, Rui M.V. Abreu, Ricardo C. Calhelha, Isabel C.F.R. Ferreira, Raquel Soares, Maria-João R.P. Queiroz “Anti-angiogenic effects of new di(heteroaryl)thioethers 1,3-diarylureas in the thieno[3,2-b]pyridine series. Role in VEGFR2 inhibition”
Symposium
 5º Simpósio de Metabolismo, Porto, Portugal
Faculty of Medicine, University of Porto, Portugal
2013 - 2013 Poster presentation - Ferreira-Pinto, Manuel J; Silva, Ana F; Justino, Joana; Ferreira, Rita M. N; Padrão, Ana I; Moreira-Gonçalves, Daniel; Carneiro, Fábio; Costa, Raquel; Leite-Moreira, Adelino; Henriques-Coelho, Tiago "Survivin Inhibition Reverses Cardiac and Pulmonary Remodeling in Monocrotaline-Induced Pulmonary Arterial Hypertension"
Conference
 American Heart Association scientific sessions, Dallas, USA
2013 - 2013 Poster presentation - 1. M. J. Ferreira-Pinto; A. F. Silva; R. Nogueira-Ferreira; A. I. Padrao; D. Moreira-Goncalves; F. Carneiro; R. Costa; L. Ribeiro; A. F. Leite-Moreira; T. Henriques-Coelho “Survivin role in pulmonary arterial hypertension”
Congress
 XXXIV Congresso Português de Cardiologia, Vilamoura, Portugal
Sociedade Portuguesa de Cardiologia, Portugal
2013 - 2013 Poster presentation - Costa R, Costa-Almeida R, Silva, A, Rodrigues I, Guardão L, Guimarães JT, Negrão R, Soares R “Vascular impairment associated with diabetic condition”
Symposium
 5º Simpósio em metabolismo, Porto, Portugal
Faculty of Medicine, University of Porto, Portugal
2013 - 2013 Poster presentation - Machado VA, Costa R, Peixoto D, Abreu RMV, Calhelha RC, Ferreira ICFR, Queiroz MJRP, Soares R “Anti-angiogenic effects of new di(hetero)arylthioethers 1,3-diarylureas in the thieno[3,2-b]pyridine series. Role in VEGFR2 inhibition”
Symposium
 5º Simpósio em Metabolismo, Porto, Portugal.
Faculty of Medicine, University of Porto, Portugal
2013 - 2013 Poster presentation - A. Sarmento-Cabral, R. Costa, M. Severo, R. Soares, L. Ribeiro “Tyrosine hydroxylase localization in mice adipose tissue under obesity”
Meeting
 2013 ASCB Annual Meeting, New Orleans, LA, USA.
2013 - 2013 Poster presentation - A. Sarmento-Cabral, R. Costa, M. Severo, R. Soares, L. Ribeiro “Expression and localization of tyrosine hydroxylase in mice adipose tissue under obesity”
Congress
 17º Congresso Português de Obesidade, Porto, Portugal.
2013 - 2013 Poster presentation - Vera Machado, Raquel Costa, Daniela Peixoto, Rui M.V. Abreu, Ricardo C. Calhelha, Isabel C.F.R. Ferreira, Raquel Soares, Maria-João R.P. Queiroz “New di(hetero)arylthioethers 1,3-diarylureas in the thieno[3,2-b]pyridine series as VEGFR-2 tyrosine kinase inhibitors: docking, synthesis and enzymatic and cellular assays”
Conference
 49th International Conference on Medicinal Chemistry, Nice, France
2012 - 2012 Poster presentation - JP Silva, R Ramos, AC Rodrigues, R Costa, L Guardão, R Soares, M Vilanova, L Domingues, MF Gama “Bioactivity of the recombinant human antimicrobial peptide LL37: a key role in wound healing through vascularization”
Congress
 3rd TERMIS (Tissue Engineering & Regenerative Medicine International Society World Congress, Vienna, Austria
2012 - 2012 Poster presentation - Rita Negrão, Raquel Costa, Delfim Duarte, Tiago Taveira Gomes, and Raquel Soares “Angiogenesis modulation by catechin - dependence on VEGF levels”
Workshop
 FEBS Workshop: Molecular and Cellular Mechanisms in Angiogenesis, Capri, Italy
2012 - 2012 Poster presentation - Duarte D, Negrão R, Costa R, Soares R “Anti-angiogenic effects of beer-derived Isoxanthohumol: A neonatal mouse retina model”
Workshop
 FEBS Workshop: Molecular and Cellular Mechanisms in Angiogenesis, Capri, Italy
2012 - 2012 Poster presentation - Raquel Costa, Rita Negrão, Ângela Castela, Delfim Duarte, Pedro Gomes, Raquel Soares “Angiogenesis in diabetic wound healing can be modulated by xanthohumol-supplemented beer”
Workshop
 FEBS Workshop: Molecular and Cellular Mechanisms in Angiogenesis, Capri, Italy
2012 - 2012 Poster presentation - Daniela Peixoto, Ricardo C. Calhelha, Pedro Soares, Rui M.V. Abreu, Hugo Froufe, Isabel C.F.R. Ferreira, Raquel Costa, Raquel Soares, Maria João R.P. Queiroz “1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 inhibitors: synthesis, docking enzymatic and cellular assays”
Meeting
 3º Encontro Nacional de Química Terapêutica, Aveiro, Portugal
2012 - 2012 Poster presentation - Queiroz, Maria João; Peixoto, Daniela; Soares, Pedro; Abreu, Rui M.V.; Froufe, Hugo J.C.; Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Costa, Raquel; Soares, Raquel “1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 tyrosine kinase inhibitors: synthesis, docking studies, enzymatic and cellular assays”
Symposium
 XXIInd International Symposium on Medicinal Chemistry, Berlin, Germany
2012 - 2012 Poster presentation - Maria-João R.P. Queiroz, Daniela Peixoto, Pedro Soares, Rui M.V. Abreu, Hugo J. C. Froufe, Ricardo C. Calhelha, Isabel C.F.R. Ferreira, Raquel Costa, Raquel Soares “Heteroarylether 1,3-diarylureas in the thieno[3,2-d]pyrimidine series as VEGFR2 tyrosine Kinase inhibitors: synthesis, docking studies, enzymatic and cellular assays”
Conference
 48th International conference on Medicinal Chemistry. Interfacing Chemical Biology and Drug Discovery. Poitiers, France
2012 - 2012 Poster presentation - Castela A, Soares R, Gomes P, Costa R, Vendeira P and Costa C “El estrés oxidativo induce alterations estructurales de proteínas en el tejido cavernoso de ratas diabéticas”
Congress
 V Congreso Andro y VI Congreso Argentino de Andrologia
2011 - 2011 Poster presentation - Delfim Duarte, Raquel Costa, Raquel Soares, Rita Negrão “Modulação da angiogénese da retina pelo isoxanto-humol”
Symposium
 19º Simpósio internacional de iniciação científica. São Paulo, Brasil
2011 - 2011 Poster presentation - Raquel Costa, Rita Negrão, Ângela Castela, Delfim Duarte, Pedro Gomes and Raquel Soares. “Effect of xanthohumol-supplemented beer in wound-healing in diabetic rats”
Conference
 5th International Conference on Polyphenols and Health, Barcelona, Spain
2011 - 2011 Poster presentation - Negrão R, Costa R, Duarte D, Azevedo I and Soares R “Isoxanthohumol regulates cellular signaling pathways involved in angiogenesis and inflammation”
Conference
 5th International Conference on Polyphenols and Health, Barcelona, Spain
2011 - 2011 Poster presentation - Raquel Costa, Rita Negrão, Ângela Castela, Delfim Duarte, Pedro Gomes and Raquel Soares “Xanthohumol-supplemented beer affect skin wound-healing in diabetic rats”
Meeting
 VI Yes Meeting, Porto, Portugal
2011 - 2011 Poster presentation - Costa R, Duarte D, Taveira T, Pirraco A, Coelho P, Guardão L, Soares R and Negrão R “The effect of xanthohumol-supplemented beer on angiogenic and inflammatory in vivo assays”
Meeting
 IJUP, Porto, Portugal
2010 - 2010 Poster presentation - “Consumption of a xanthohumol supplemented beer alters skin wound-healing process: angiogenesis and inflammation regulation”
Symposium
 Cell symposium: Inflammation and disease. Lisboa, Portugal
2010 - 2010 Poster presentation - Costa R, Magalhães PJ, Duarte D, Taveira T, Mendanha M, Soares R and Negrão R “Inhibition of angiogenesis and inflammation by xanthohumol-enriched beer in a rat skin-wound healing model”
Meeting
 IJUP
2010 - 2010 Poster presentation - Rita Negrão, Raquel Costa, Delfim Duarte, Tiago Taveira, Mário Mendanha, Raquel Soares “Angiogenic and Inflammatory activities are modulated in vivo by polyphenol supplemented beer”
Conference
 FASEB, California, USA
2008 - 2008 Poster presentation - Costa R, Pirraco A, Carneiro A, Falcão M, Rocha A, Soares R “Effects of bevacizumab on human microvascular endothelial cells. Implications in Age-related Macular Degeneration”
Congress
 XVI Congresso Nacional de Bioquímica. Açores, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2024/01 A new insight of grape seed extract in skincare
(Thesis) Main arguer
 Maria Leonor Teixeira Pinto de Castro (Master)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2024/01 Functional curcumin scaffolds to tackle chronic wounds
(Thesis) Main arguer
 Tiago Silva Barros (Master)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2023/11/28 Umbilical cord mesenchymal stem cells effect on melanoma progression
(Thesis) Main arguer
 Pablo Rende Fernandes (Master)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2023/11/17 Têxtil para aplicação médica - o impacto da origem dos materiais na citocompatibilidade com células humanas
(Thesis) Main arguer
 Nuno Fernando Matos Sousa Fernandes (Master)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2022/12/07 Nanotechnological approaches for treating skin cancer: from drug delivery nanoformulations to 3D models of skin cancer
(Thesis) Main arguer
 Marta Oliveira Vasconcelos Rosadas (Master)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2022/11/07 von Willebrand Factor as a Biomarker of Aortic Stenosis Severity
(Thesis) Main arguer
 Ana Rita Nunes Albuquerque (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2021/12 Unravelling prostate cancer paradox – molecular, metabolic and cytometric mechanisms in type 2 diabetes and metabolic syndrome
Supervisor
 André Miguel Sousa (Master)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2021/11 Criopreservação das células estaminais do sangue do cordão umbilical
(Thesis) Main arguer
 Carolina Rua Franco (Master)
Instituto Politécnico do Porto, Portugal
2021/07 Effect of umbilical cord mesenchymal stem cell secretome in cancer cell progression
(Thesis) Main arguer
 Ana Beatriz Lobo de Almeida (Other)
Instituto Politécnico do Porto, Portugal
2021/07 Xenobiotic-free isolation of umbilical cord mesenchymal stem cells
(Thesis) Main arguer
 Martina Dourado Gonçalves (Other)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2019/12/09 Low doses of ionizing radiation induce angiogenesis: therapeutic implications
(Thesis) Main arguer
 Filipa Gil Marques (PhD)
Faculty of Medicine, University of Lisbon, Portugal
2019/09 The role of gut microbiota-host interaction in obesity and metabolic disturbances
(Thesis) Arguer
 Eva Lau Gouveia (PhD)
Faculty of Medicine, University of Porto, Portugal

Association member

Society Organization name Role
2017 - Current Sociedade Portuguesa de Diabetes Member
2014/01 - Current GIFT - Grupo de investigação fundamental e translacional da Sociedade Portuguesa de Diabetes Research

Committee member

Activity description
Role 		Institution / Organization
2022/06 - Current Member of Task Force Advance Training
Member
 Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

Conference scientific committee

Conference name Conference host
2019/10 - 2019/10 11º Simpósio em Metabolismo Faculty of Medicine, University of Porto
2018/10 - 2018/10 10º Simpósio em Metabolismo Faculty of Medicine, University of Porto
2017/10 - 2017/10 9º Simpósio em Metabolismo Faculty of Medicine, University of Porto

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022/09 - Current Invited assistant professor of the Curricular Unit “Tissue engineering and bioprinting” Engenharia Biomédica (Mestrado integrado) Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2021/10 - Current Coordinator of the session "Biochemistry in obesity" in the Pos-Graduation Course of Nutrition Nutrition (Postgraduate Certificate) Universidade Federal do Rio de Janeiro, Brazil
2021/06 - Current Lecturer in the Curricular Unit of "Animal Models of Disease" entitled "Animal models of obesity" Metabolismo ¿ Biopatologia e Experimentação (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal
2020/09/01 - Current Coordinator of the Curricular Unit: Methodologies on Angiogenesis Metabolismo ¿ Biopatologia e Experimentação (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal
2011/05 - Current Lecturer in the Curricular Unit of "Angiogenesis" Metabolismo - Clínica e Experimentação (Doutoramento) Faculty of Medicine, University of Porto, Portugal
2011/05 - Current Lecturer in the Curricular Unit of "Angiogenesis and Inflammation in cancer" Medicina e Oncologia Molecular (Mestrado integrado) Faculty of Medicine, University of Porto, Portugal
2011 - Current Lecturer in the Curricular Unit of "Angiogenesis and Inflammation in cancer" Medicina e Oncologia Molecular (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2020/10/01 - 2023/07 Invited Adjunct Professor of Biochemistry (Licenciatura) School of Health, Polytechnic Institute of Porto., Portugal
2019/11 - 2019/11 Lecturer in Master of Clinical Nutritional entitled "Metodologia em Investigação Animal" Nutrição Clínica (Mestrado integrado) Faculty of Nutritional Sciences, University of Porto, Portugal
2017/12 - 2017/12 Invited professor of Biochemistry Medicina Dentária (Mestrado integrado) Faculty of Medical Dentistry, University of Porto, Portugal
2017/08/28 - 2017/09/05 Workshop “Prática laboratorial e metodologias em angiogénese” (Postgraduate Certificate) Hemocentro - UNICAMP, Brazil
2015 - 2016 Workshop "Angiogenic methodologies- Hands on lab course" (Outros) Faculty of Medicine, University of Porto, Portugal
2011/09 - 2014/09 Practical classes of Biochemistry Medicina (Mestrado integrado) Faculty of Medicine, University of Porto, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2019/10 - 2019/10 Poster session of XI Symposium in Metabolism
Evaluator
 Faculty of Medicine, University of Porto, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2021/04 - Current Journal of Cellular and Molecular Medicine (1582-1838) Wiley-Blackwell
2021/01 - Current Guest editor of Special Issue "Women in Vascular Disease: from Pathology to Regenerative Engineering" (2218-273X) MDPI
2020 - Current Antioxidants (2076-3921) MDPI
2020 - Current Molecules ( 1420-3049) MDPI
2020 - Current Food Research International Elsevier
2020 - Current Journal of Clinical Medicine (2077-0383) MDPI
2019 - Current Nutrients (2072-6643) MDPI
2019 - Current International Journal of Nanomedicine (1178-2013) Dove Press
2018/11 - Current Guest editor of Special Issue "Metabesity and Tissue Regeneration: New Therapies for Emerging Challenges" (1422-0067) MDPI
2018 - Current Porto Biomedical Journal (2444-8664) Wolters kluwer

Mentoring / Tutoring

Topic Student name
2019/04 - 2019/12 Development of Wound Dressings Based on Cyanobacterial Extracellular Heteropolysaccharide Luís Costa
2013/04 - 2019/05 Targeting the endothelial cell metabolism and function crosstalk as a means to unravel the angiogenic paradox in type 1 diabetes mellitus Carolina Campos Silva
2015/09 - 2016/11 Coffee Diterpenes: Quantification and Anti-angiogenic Effects Marzieh Moeenfard
2013/01 - 2016/07 Synthesis of novel heterocyclic compounds based on rational design and evaluation of their antitumor and antiangiogenic potential in human endothelial and tumor cell lines with tyrosine kinase membrane receptors as targets Vera Alexandra Pereira Machado
2014/09 - 2015/07 Xanthohumol restores hepatic glucolipid metabolism balance in type 1 diabetic animals Mário Fontes
2011 - 2013 Mentor in Universidade Junior High-school students
2011/01 - 2011/09 Avaliação do paradoxo angiogénico na diabetes mellitus 2 Ana Rita Almeida Calixto Silva

Other jury / evaluation

Activity description Institution / Organization
2019/05 - Current Member of the jury to select a MsC candidate to develop research work under the project i3S strategic project UID/BIM/04293/2019, funded by FCT i3S - Instituto de Investigação e Inovação em Saúde, Portugal
2019/06 - 2019/06 Member of the jury to select a PhD candidate for an assistant researcher contract on the project “Bioengineered therapies for infectious diseases and tissue regeneration” financed by N2020: NORTE-45-2015-2 Faculty of Medicine, University of Porto, Portugal
Distinctions

Award

2023 Prize Bragança Parreira - RSoares, R Fernandes, WR Brito, D Martins-Mendes, R Costa, F Gojon
Sociedade Portuguesa de Diabetologia, Portugal
2020 Honorable mention Pedro Eurico Lisboa for the best publication in 2019 "Establishing a link between endothelial cell metabolism and vascular behaviour in a type 1 diabetes mouse model"
Sociedade Portuguesa de Diabetologia, Portugal

Lilly Portugal Produtos Farmacêuticos Lda, Portugal
2016 Prize for best poster presentation - Costa R, Rodrigues I, Guardão L, Negrão R and Soares R. Polyphenols as diabetic modulators: Relevance to angiogenic paradox
Simpósio em Metabolismo - FMUP, Portugal
2010 Award of high merit. Raquel Costa, Rita Negrão and Raquel Soares. “Effect of beer polyphenols on angiogenesis and modulation of inflammation”
iBeSa - Instituto de Bebidas e Saúde, Portugal
2009 3rd prize for best oral communication. Costa R, Mendanha M, Duarte D, Taveira T, Negrão R and Soares R. “Beer polyphenols modulate angiogenesis and inflammation: in vitro and in vivo results”
Associação Portuguesa dos Nutricionistas, Portugal

Title

2022 Prize for best poster presentation of Fundamental Research ¿- Costa R, Batista-Silva S, Bernardes B, Rodrigues I, Teixeira-Pinto M, Pintado M, Soares R and Leite-Oliveira A
Sociedade Portuguesa de Diabetologia, Portugal
2021 Prize for best oral presentation - Beatriz Bernardes, Raquel Costa*, Carlos García-Gonzaléz* and Ana Leite Oliveira* “Silk fibroin aerogel particles via emulsion-gelation method for the treatment of chronic wounds”
Thermulon Ltd, United Kingdom
2021 Prize for best oral presentation - Beatriz G Bernardes, Clara López-Iglesias, Raquel Costa*, Carlos García-Gonzaléz* and Ana Leite Oliveira* “Silk fibroin aerogel particles via emulsion-gelation method for the treatment of chronic wounds”
European Society for Biomaterials, Portugal
2021 Prize for best oral presentation - Bernardes BG, Del Gaudio, P.; Alves, P.; Costa, R.; García-Gonzaléz, CA.; Oliveira, AL “Bio-aerogéis: materiais nanoestruturados promissores na gestão de fluidos, cicatrização e regeneração de feridas”
Associação Portuguesa Tratamento das Feridas, Portugal
2016 Servier Award in Cardiac Insufficiency - fundamental research “O terameprocol como modulador da sinalização vascular num modelo experimental de hipertensão arterial pulmonar”
Sociedade Portuguesa de Cardiologia, Portugal
2015 Honoral mention for best oral presentation. Fontes M, Costa R, Soares R. “Beer polyphenols can modulate angiogenic and metabolic pathways in T2 diabetes”
Yes Meeting, Portugal
2013 Basic Research Award, honorable mention. Sarmento-Cabral, R. Costa, M. Severo, R. Soares, L. Ribeiro. “Expression and localization of tyrosine hydroxylase in mice adipose tissue under obesity”
Congresso Português de Obesidade, Portugal
2012 Honorable mention in the category Oncology and Molecular Biology. Ferreira-Pinto MJ, Silva AF, Ferreira R, Padrão AI, Moreira-Gonçalves D, Carreiro F, Brandão J, Costa R, Ribeiro L, Leite-Moreira AF and Henriques-Coelho T. “Survivin role in pulmonar arter
Yes Meeting, Portugal
2011 1st Prize Post-Graduate Oncology & Molecular Biology. Raquel Costa, Rita Negrão, Ângela Castela, Delfim Duarte, Pedro Gomes, Raquel Soares. “Xanthohumol-supplemented beer affect skin wound-healing in diabetic rats”
Yes Meeting, Portugal
2011 Best presentation in the field “Health Sciences”. Delfim Duarte, Raquel Costa, Raquel Soares, Rita Negrão. “Isoxanthohumol inhibits in vivo vascular proliferation and stabilization”
IJUP, Portugal
2009 Best poster communication in post-graduation category. Raquel Costa, Tiago Taveira, Delfim Duarte, Rita Negrão and Raquel Soares. “Angiogenic and inflammatory activities modulated by beer polyphenols, taking skin-wound healing as a model”
Yes Meeting, Portugal