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Luís received a PhD in Biological and Chemical Sciences from the University of Trás-os-Montes and Alto Douro in 2016 with the thesis titled" Towards an understanding of ketamine teratogenicity in zebrafish early development ". He has one degree in Chemistry (since 2007) and in Biochemistry (since 2009) from the University of Trás-os-Montes and Alto Douro and his training also includes a master in Laboratory Analysis since 2009 from the same University. His research interests include most areas of pharmacology/toxicology, with particular emphasis on understanding the role of oxidative stress and cellular death mechanisms on in-vivo developmental-toxicant interactions and the associated health risks. Since 2018, Luís has been recently awarded a junior research contract in the 2021 Individual Scientific Employment Stimulus Competition (CEEC) by the Portuguese national funding agency for science, research and technology (FCT) to work at the University of Trás-os-Montes e Alto Douro (UTAD). He is developing research related with the cellular stress responses induced by anaesthetics in both adult and larval stages of the laboratory zebrafish. During his research career, Luís has published more than 85 articles in specialized journals and 7 book chapters, being reviewer for more than 100 journals. Luís was the editor of a book on teratogenicity methods and protocols, which was published in 2018 by Springer and re-published in a 2nd edition in 2024. He is currently the editor of three special issue from MDPI and Frontiers. Between 2010 and 2020 he participated in several research projects directly or indirectly related to his doctoral research area. He has more than 100 contributions in scientific meetings and scientific dissemination seminars/workshops in Portugal and abroad. Luís has also been supervisor and co-supervisor of different BSc and MSc concluded and on-going theses. He is currently supervising or co-supervising three PhD and one Master students.
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Identification

Personal identification

Full name
Luís Félix

Citation names

  • Félix, Luís Manuel Lourenço
  • Luís Félix
  • Luís M. Félix

Author identifiers

Ciência ID
531D-9859-B602
ORCID iD
0000-0001-9870-6666
Google Scholar ID
bjQpfw8AAAAJ&hl
Researcher Id
1174916/luis-felix/
Scopus Author Id
26658292100

Email addresses

  • luis.felix@ibmc.up.pt (Professional)
  • lfelix@utad.pt (Professional)
  • luis_felix@sapo.pt (Personal)

Addresses

  • R D Jose Correia de Lacerda Bl 10 Ent C 6 Esq, 5000-440, Vila Real, Vila Real, Portugal (Personal)

Knowledge fields

  • Exact Sciences - Chemical Sciences
  • Agrarian Sciences - Veterinary Sciences
  • Natural sciences - Biological Sciences
  • Medical and Health Sciences - Basic Medicine

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Intermediate (B1) Advanced (C1) Intermediate (B1) Advanced (C1)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2016
Concluded
 Chemical and Biological Sciences (Doutoramento)
Major in Área de especialidade: Ciências Biológicas
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
"Towards an understanding of ketamine teratogenicity in zebrafish early development" (THESIS/DISSERTATION)
 Approved
2011/12/05 - 2011/12/14
Concluded
 Laboratory Aquatic Animal Sciences Course (Outros)
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Approved
2006/03/23 - 2009/06/24
Concluded
 General English (Outros)
Wall Stree Institute, Portugal
 90/100
2009
Concluded
 Biochemistry (Licenciatura)
Universidade de Trás-os-Montes e Alto Douro, Portugal
 13/20
2009
Concluded
 Laboratory Analysis (Mestrado)
Universidade de Trás-os-Montes e Alto Douro, Portugal
"Avaliação da acção do Carvedilol na nefrotoxicidade induzida por gentamicina em rato" (THESIS/DISSERTATION)
 15/20
2007
Concluded
 Chemistry (Licenciatura)
Universidade de Trás-os-Montes e Alto Douro, Portugal
 13/20
Affiliation

Science

Category
Host institution 		Employer
2022 - Current Researcher (Research) Universidade de Trás-os-Montes e Alto Douro, Portugal
2018/12/10 - 2021/09/21 Researcher (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Others

Category
Host institution 		Employer
2016/07 - 2018/12 Bolseiro de Investigação (BI) - Master Universidade de Trás-os-Montes e Alto Douro, Portugal
2013/10 - 2015/09/09 Bolseiro de Investigação (BI) - Master Universidade de Trás-os-Montes e Alto Douro, Portugal
2012/12 - 2013/09 Bolseiro de Investigação (BI) - Master Universidade do Porto, Portugal
2010/12 - 2012/12 Bolseiro de Investigação (BI) - Master Universidade de Trás-os-Montes e Alto Douro, Portugal
2010/03 - 2010/07 Bolseiro de Investigação (BI) - Bachelor Universidade de Trás-os-Montes e Alto Douro, Portugal
2010/01 - 2010/03 Voluntariado Universidade de Trás-os-Montes e Alto Douro, Portugal
2006/01 - 2006/06 Bolseiro de Investigação Científica (BIC) -Undergraduate Universidade de Trás-os-Montes e Alto Douro, Portugal
Projects

Grant

Designation Funders
2021/02/01 - 2025/01/31 Establishment of different matrices to measure cortisol in zebrafish under acute and chronic stressful situations
2020.04584.BD
10.54499/2020.04584.BD
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Centro Interdisciplinar de Investigação Marinha e Ambiental da Madeira, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/01 - 2023 Anaesthetic efficiency and biochemical effects of thymol and menthol for improving well-being in aquaculture using zebrafish model
SFRH/BD/144904/2019
Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2016/07 - 2018/12 INTERACT - Integrative Research in Environment, Agro-Chain and Technology
NORTE-01-0145-FEDER-000017
Master Student Fellow
Universidade de Trás-os-Montes e Alto Douro, Portugal
Concluded
2013/10 - 2015/09 Zebrafish (Danio rerio) anaesthesia and potential implications in research
PTDC/CVT-WEL/3877/2012
Master Student Fellow
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2012/12 - 2013/09 Effects of Ketamine anaesthesia in animal models used on research
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/99022/PT
Master Student Fellow
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/12 - 2012/12 Effects of Ketamine anaesthesia in animal models used on research
PTDC/CVT/099022/2008
Master Student Fellow
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/03 - 2010/07 Synthesis and structural characterization of new squarilic dyes for affinity chromatography
LR1-CQVR
Research Fellow
Universidade de Trás-os-Montes e Alto Douro Centro de Química Vila Real, Portugal
Concluded

Contract

Designation Funders
2022/05/16 - 2028/05/15 Menthol and Thymol loaded in mucoadhesive nanocapsules for the transportation of ornamental fish
2021.00458.CEECIND/CP1690/CT0001
10.54499/2021.00458.CEECIND/CP1690/CT0001
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - 2025/12/31 Institute for Research and Innovation in Health
LA/P/0070/2020
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/03/01 - 2024/02/29 Enantioselective ecotoxicity and bioaccumulation of psychoactive substances
PTDC/CTA-AMB/6686/2020
Universidade do Minho, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/06/01 - 2022/02/28 Preclinical efficacy of sulforaphane or Brassica whole extract: a strategy to fight obesity and valorize Brassica byproducts
PTDC/ASP-HOR/29152/2017
Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/07/26 - 2021/12/25 Refining zebrafish anesthesia: economical, clinical and animal welfare implications
PTDC/CVT-CVT/29542/2017
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/12/10 - 2021/09/21 ZEBREFINE: Optimization of anesthesia in zebrafish: economic, clinical and animal welfare implications
C490697640-00081657
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 Institute for Research and Innovation in Health Sciences
UID/BIM/04293/2019
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 Centre for the Research and Technology of Agro-Environmental and Biological Sciences
UID/AGR/04033/2019
Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2013/07/01 - 2015/09/30 Zebrafish (Danio rerio)anaesthesia and potential implications in research - reduction, replacement and refining techniques/procedures
PTDC/CVT-WEL/4672/2012
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Instituto de Biotecnologia e Bioengenharia, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2014/06/30 A lipidomic approach of Alzheimer`s disease - Study of lipid profile changes in brain mitochondria
PTDC/SAU-NMC/115865/2009
Universidade de Trás-os-Montes e Alto Douro Centro de Ciência Animal e Veterinária, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade de Aveiro, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2013/12/31 Strategic Project - UI 772 - 2011-2012
PEst-OE/AGR/UI0772/2011
Universidade de Trás-os-Montes e Alto Douro Centro de Ciência Animal e Veterinária, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Alves-Pimenta, Sofia; Félix, Luís; Colaço, Bruno; Oliveira, Paula A.; Venâncio, Carlos. "Guidelines on Developmental Toxicity Tests: Brief Insights". In Methods in Molecular Biology, 39-65. Springer US, 2024.
    10.1007/978-1-0716-3625-1_2
  2. Lei, Mariana Caipira; Félix, Luís; Venâncio, Carlos. "Protocol of Geometric Morphometrics for Teratogenicity Testing". In Methods in Molecular Biology, 459-468. Springer US, 2024.
    10.1007/978-1-0716-3625-1_28
  3. Vieira, Raquel S. F.; Venâncio, Carlos; Félix, Luís. "Cortisol Quantification for Assessing Stress-Induced Changes in Zebrafish Larvae". In Methods in Molecular Biology, 483-493. Springer US, 2024.
    10.1007/978-1-0716-3625-1_30
  4. Félix, Luís. "A Chromogenic Quantification of Protein Expression in Zebrafish Larvae". In Methods in Molecular Biology, 515-532. Springer US, 2024.
    10.1007/978-1-0716-3625-1_33
  5. Santos, Dércia; Vieira, Raquel; Luzio, Ana; Félix, Luís. "Zebrafish Early Life Stages for Toxicological Screening: Insights From Molecular and Biochemical Markers". In Advances in Molecular Toxicology, 151-179. Elsevier, 2018.
    10.1016/b978-0-444-64199-1.00007-5
  6. Alves-Pimenta, Sofia; Félix, Luís; Colaço, Bruno; Oliveira, Paula A.; Venâncio, Carlos. "Teratology Study Guidelines: An Overview". In Methods in Molecular Biology, 33-59. Springer New York, 2018.
    10.1007/978-1-4939-7883-0_2
  7. Félix, L.; Antunes, L.; Campos, S.; Venâncio, C.; Coimbra, A.M.. "Recreational Use of Ketamine and Its Interaction with NMDA Receptors". In 65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017). 2016.
    10.1016/B978-0-12-800212-4.00062-5
Conference abstract
  1. Jorge, Sara; Félix, Luís Manuel Lourenço; Costas, Benjamin; Ramos-Pinto, Lourenço; R. Teixeira, Sofia; Valentim, Ana M. "New methods for cortisol assessment in chronically stressed zebrafish". Paper presented in Animal Health Symposium, Porto, 2024.
    Published
  2. Jorge, Sara; Félix, Luís Manuel Lourenço; Costas, Benjamin; Ramos-Pinto, Lourenço; Teixeira, Sofia R.; Valentim, Ana. "Non-Terminal Methodologies to Measure Cortisol in Chronically Stressed Zebrafish". Paper presented in Animal and Veterinary Sciences Doctoral Programme Workshop, Porto, 2024.
    Published
  3. Chowdhury Soumitra; Viswanath, Kiron; Francisco Manuel Pereira Peixoto ; Sandra Mariza Monteiro; Luís Félix. "Bioenergetic cost on zebrafish intestine caused by a ubiquitous pollutant, glyphosate". Paper presented in EBEC2024, 2024.
  4. Jorge, Sara; Ferreira, Jorge; Félix, Luís Manuel Lourenço; Collins, Mark; Costas, Benjamin; Olsson, Anna; Valentim, Ana. "Navigating into the 2Rs of zebrafish research: refinement and reduction examples". Paper presented in Portuguese Society for Laboratory Animals (SPCAL) meeting, Coimbra, 2024.
  5. Ribeiro, Ondina; Félix, Luís Manuel Lourenço; Cláudia Ribeiro; Sandra Mariza Veiga Monteiro; Carrola, João soares. "Zebrafish as a valuable vertebrate model to study teratogenicity of pharmaceuticals and psychoactive substances". Paper presented in II TOXRUN International Congress 2023, 2023.
  6. Ribeiro, Ondina; Luís Félix; Claudia Ribeiro; Carrola, João soares. "Butylone effects on the behaviour of zebrafish (Danio rerio) larvae". Paper presented in II TOXRUN International Congress 2023, 2023.
  7. Dércia Santos; LUZIO, ANA; Luís Félix; Monteiro, Sandra. "Behavioral responses in zebrafish (Danio rerio) to microplastics and copper exposure.". Paper presented in Animal biology early career researcher symposium, Helsinki, 2022.
  8. Rita Sequeira; Félix, Luís Manuel Lourenço; S.V. Monteiro; Tania Martins; Paula Oliveira; M.M. Pires; Colaço, Bruno; et al. "Effect of broccoli (Brassica oleracea var italica) flour by-products on hepatic oxidative stress in a murine model of obesity". Paper presented in European Congress on Obesity (ECO) 2021, 2021.
  9. Ferreira, T.; Germano Augusto Bacin Lanzarin; Venâncio, C.; Félix, Luís Manuel Lourenço; Oliveira PA. "Therapeutic properties of Tilia platyphyllos Scop. in K14HPV16 mice.". Paper presented in IberPhenol - International Virtual Conference - Advances in the role of phenols in health effects and other uses, 2020.
    Published
  10. Jesus, T; Pires, M; Germano Augusto Bacin Lanzarin; Félix, Luís Manuel Lourenço; Venâncio, C.; Eduardo Rosa; Oliveira, PA. "The antioxidant effect of spearmint (Mentha spicata) in a HPV-16-transgenic mouse model.". Paper presented in IberPhenol - International Virtual Conference - Advances in the role of phenols in health effects and other uses, 2020.
    Published
  11. Carlos Venâncio; Raquel Vieira; Sandra Mariza Monteiro; Félix, Luís Manuel Lourenço. "Developmental and toxicological joint effects of selected fungicide mixtures in zebrafish embryo". Paper presented in EuroTox 2019, 2019.
  12. Carla Santos; Joana Balça-Silva; Félix, Luís Manuel Lourenço; Ana M. Valentim; Maria Pires; C Gonçalves; Maria de Lurdes Pinto. "Effects of ketamine exposure in zebrafish central nervous system proliferation capability". 2018.
    10.23919/emf-med.2018.8526060
  13. Parra, S.; Félix, Luís Manuel Lourenço; Dércia Santos; Gago, J.; Varandas, Simone da Graça Pinto ; Sandra Mariza Monteiro. "Catalase biomarker response induced by microplastics, cadmium and their mixtures on the exotic invasive bivalve Corbicula fluminea.". Paper presented in XIX Conference of the Iberian Association of Limnology. Inland waters and XXI century challenges: from scientific knowledge to environmental management, Coimbra, 2018.
    Published
  14. PARRA, S.; Félix, Luís Manuel Lourenço; Dércia Santos; GAGO, J.; Sandra Mariza Monteiro; Simone da Graça Pinto Varandas. "Oxidative stress response in gonads of Asian clam, Corbicula fluminea, simultaneously exposed to microplastics and cadmium.". Paper presented in FMCS International Freshwater Mollusk Meeting, Verbania, 2018.
    Published
  15. Vieira, R.; Sandra Mariza Monteiro; Venâncio, Carlos A.S.; Félix, Luís Manuel Lourenço. "Ecotoxicidade de fungicidas avaliada no desenvolvimento embrionário de peixe-zebra.". Paper presented in II Simpósio Internacional de Águas, Solos e Geotecnologias (SASGEO), III Jornadas INTERACT, Vila Real, 2018.
    Published
  16. Taghouti, M; Félix, L; Martins-Gomes, C; Santos, JA; Nunes, FM; Silva, AM. "Profiling, anti-radical activity and bioactivity of Thymus mastichina, Thymus x citriodorus and Thymus vulgaris aqueous extracts". 2017.
    10.1055/s-0037-1608264
  17. Félix, L; Teixeira, I; Taghouti, M; Nunes, FM; Silva, AM. "Phytochemical profile, antioxidant activity and cytotoxicity of different extracts of Thymus vulgaris ssp. fragantissimus". 2017.
    10.1055/s-0037-1608473
  18. Félix, L; Coutinho, T; Barejão, A; Taghouti, M; Silva, AM. "Biological activity and phytochemical analysis of extracts obtained from Santolina rosmarinifolia L.". 2017.
    10.1055/s-0037-1608476
  19. Santos, C.; Félix, L.; Neves, M.; Coimbra, A.; Valentim, A.M.; Antunes, L.; Gonçalves, C.; Carmo, A.; Pinto, M.L.. "Refinement Techniques in Zebrafish Anaesthesia - Results from a Pilot Study". 2015.
    10.1017/S1431927615014270
  20. Félix, Luís Manuel Lourenço; Coimbra, Ana M.; Antunes, L.. "Ketamine-induced developmental toxicity and apoptosis in zebrafish embryos". Paper presented in Euroanaesthesia 2013, Barcelona, 2013.
    Published
  21. Campos, Sónia; Félix, Luís Manuel Lourenço; Venâncio, C.; Antunes, L.; Peixoto, F.. "Decrease of state III mitochondrial respiration by prolonged infusion of propofol vehicle in rabbit liver". Paper presented in Euroanaesthesia 2013, Barcelona, 2013.
    Published
  22. Félix, Luís Manuel Lourenço. "Rat liver mitochondrial complex I impairment after ketamine chronic treatments". Paper presented in Euroanaesthesia 2012, Paris, 2012.
    Published
  23. Félix, Luís Manuel Lourenço. "Ketamine can lead to malformation of zebrafish (Danio rerio) larvae". Paper presented in Euroanaesthesia 2012, Paris, 2012.
    Published
  24. Correia, F.; Félix, L.; Summavielle, T.; Antunes, L.; Peixoto, F.. "Effects of Graded Doses of Propofol in Mitochondrial Function in Rat". Paper presented in Anesthesiology 2012, Washington, 2012.
    Published
  25. Pinho, P. G.; Correia, F.; Félix, L.; Antunes, L.; Peixoto, F.. "Evaluation of the Effect of Propofol Anesthesia, in Rat Liver Mitochondrial Bioenergetics". Paper presented in Anesthesiology 2011, Chicago, 2011.
    Published
  26. Félix, Luís Manuel Lourenço. "Acute Effects of Ketamine Anesthesia in Brain Mitochondrial Function and Redox State in a Rat Model". Paper presented in Anesthesiology 2011, Chicago, 2011.
    Published
  27. Correia, F.; Félix, L.; Summavielle, T.; Antunes, L.; Peixoto, F.. "Propofol Anesthesia With Lower Doses Interferes with Brain Mitochondria Bioenergetics in Rat". Paper presented in Anesthesiology 2011, Chicago, 2011.
    Published
  28. Diogo, C. V.; Félix, L.; Vilela, S.; Burgeiro, A.; Barbosa, I.A.; Carvalho, M.J.M.; Oliveira, Paulo J.; et al. "Possible anti-cancer application of the phytochemicals daphnetoxin and daphnoretin-relevance of mitochondrial toxicity". Paper presented in 44th Annual Scientific Meeting of the European Society for Clinical Investigation, Bari, 2010.
    Published
  29. Vilela, S.; Santos, Dario J.S.L.; Félix, L.; Antunes, L.; Almeida, José M.; Peixoto, F.. "Brain mitochondrial bioenergetics is differentially affected by anesthetics fentanil and remifentanil". Paper presented in 13th European Bioenergetics Conference, Pisa, 2008.
    Published
  30. Félix, Luís Manuel Lourenço. "The Analgesic Fentanyl Impair Oxidative Metabolism in Rat Brain Mitochondria". Paper presented in Anesthesiology 2007, San Francisco, 2007.
    Published
Conference poster
  1. Rocha, Cláudia Alexandra; Félix, Luís Manuel Lourenço; Sandra Mariza Monteiro; Carlos Venâncio. "Natural Monoterpenes as Analgesics: A Way to Improve Welfare in Zebrafish". Paper presented in Animal Health Symposium (2nd Edition), 2024.
  2. Rafael Xavier Martins; Matheus Alves Soares De Carvalho; Maria Eduarda De Souza Maia; Terezinha Maria De Souza; Thiago Lopes Rocha; Luís Félix; Davi Felipe Farias. "2,4-D herbicide-induced hepatotoxicity: Unveiling disrupted liver functions and associated biomarkers". Paper presented in XVII ECOTOX, 2024.
  3. Jorge, Sara; Félix, Luís Manuel Lourenço; Costas, Benjamin; Ana M Valentim. "Chronobiological insights in zebrafish: exploring trunk and skin mucus cortisol fluctuations". Paper presented in UFAW International animal conference, 2024.
  4. Dércia Santos; João Sousa; Inês Gonçalves ; Luís Félix; LUZIO, ANA; Saavedra, Maria José ; Sandra Mariza Monteiro. "The effect of polyethylene and polystyrene microplastics combined with copper in behavior and biochemical biomarkers of zebrafish (Danio rerio) brain". Paper presented in SEB's Annual Meeting, 2024.
  5. Ribeiro, Ondina; Félix, Luís Manuel Lourenço; Ribeiro, Cláudia; Tiritan, Maria Elizabeth; Correia, Alberto Teodorico; Carrola, João soares. "Assessment of the enantiotoxic effects of amphetamine (AMP) and 3,4-methylenedioxymethamphetamine (MDMA) on zebrafish (Danio rerio) embryo". Paper presented in X Iberian Congress of Ichthyology (SIBIC 2024), 2024.
  6. Rocha, Cláudia Alexandra; Luís Félix; Sandra Mariza Monteiro; Carlos Venâncio. "Antinociceptive Analysis of Eugenol, Menthol, Thymol and Carvacrol in a Zebrafish (Danio rerio) Larval Model". Paper presented in II Ciclo de Encontros: Utilização de Animais com Fins Experimentais, 2024.
  7. Ribeiro, Ondina; Félix, Luís Manuel Lourenço; Ribeiro, Cláudia; Tiritan, Maria Elizabeth; Carrola, João soares. "Evaluation of oxidative stress and apoptosis responses in zebrafish (Danio rerio) larvae after butylone exposure". Paper presented in III 1H-TOXRUN INTERNATIONAL CONGRESS 2024, 2024.
    https://doi.org/10.48797/sl.2024.210
  8. Ana Patricia Gomes; Sandra Mariza Monteiro; Carlos Venâncio; Luís Félix. "The effects of glyphosate exposure in zebrafish neurologic system: A review". Paper presented in 2º Congresso Nacional sobre Alterações Climáticas, 2024.
  9. Ribeiro, Ondina; Félix, Luís Manuel Lourenço; Ribeiro, Cláudia; Carrola, João soares. "Behaviour assays to evaluate the impacts of psychoactive substances in adult zebrafish". Paper presented in XX Congress of the Portuguese Ethological Society, 2023.
  10. Ribeiro, Ondina; Félix, Luís Manuel Lourenço; Ribeiro, Cláudia; Gonçalves, Virgínia M. F.; Tiritan, Maria Elizabeth; Carrola, João soares. "Effects of amphetamine racemic and its enantiomers on zebrafish avoidance behaviour". Paper presented in XX Congress of the Portuguese Ethological Society, 2023.
  11. Ribeiro, Ondina; Félix, Luís Manuel Lourenço; Ribeiro, Cláudia; Carvalho, Ana Rita; Gomes, Ana; Gonçalves, Virgínia M. F.; Tiritan, Maria Elizabeth; Carrola, João soares. "Evaluation of the potential toxicity of butylone in zebrafish larvae through biochemical biomarkers". Paper presented in Inov4Agro Scholarship Researchers' Day, 2023.
    https://doi.org/10.5281/zenodo.10362443
  12. Gomes, Ana; Ribeiro, Ondina; Félix, Luís Manuel Lourenço; Ribeiro, Cláudia; Carrola, João soares. Corresponding author: Gomes, Ana. "Assessment of embryonic development of zebrafish (Danio rerio) exposed to a mixture of psychoactive substances". Paper presented in Inov4Agro Scholarship Researchers' Day, 2023.
    https://doi.org/10.5281/zenodo.10362443
  13. Raquel Vieira; Carlos Venâncio; Luís Félix. "Use of natural anaesthetics for the management of fish stress with a view to sustainable production and welfare improvement". Paper presented in Molecules4Life, 2023.
  14. Jorge, Sara; Félix, Luís Manuel Lourenço; Costas, Benjamin; Valentim, Ana; Jorge, Sara; Benjamín Costas; Ana Maria Valentim. "Diving into zebrafish stress: skin mucus cortisol as a stress biomarker". Paper presented in Aquaculture Europe 2023, 2023.
  15. Santos, C.A.; Félix, Luís Manuel Lourenço; Valentim, Ana M; Antunes, Luis Miguel Joaquim Marques; Pinto, Maria de Lurdes. Corresponding author: Pinto, Maria de Lurdes. "Effects of ketamine administration in the expression of Sox 2 in zebrafish CNS". Paper presented in Joint congress of Veterinary Pathology and Veterinary Clinical Pathology, 2023.
  16. Luís Félix; Raquel Vieira; Sandra Mariza Monteiro; Carlos Venâncio. "A meta-analytic review of monoterpene for fish anaesthesia". Paper presented in Ciência 2023 - Encontro com a ciência e a tecnologia em Portugal, 2023.
  17. Raquel Vieira; Carlos Venâncio; Luís Félix. "Exploring the effects of stressful stimuli on zebrafish: behavioral, metabolic, and biochemical perspectives". Paper presented in Ciência 2023 - Encontro com a ciência e a tecnologia em Portugal, 2023.
  18. Ribeiro, Ondina; Luís Félix; Cláudia Ribeiro; Tiritan, Maria Elizabeth; RIBEIRO, Ana Rita Lado; Carrola, João soares. "Enantiotoxicity of Butylone on Zebrafish Larvae Behaviour - Preliminary Data". Paper presented in 18TH INTERNATIONAL CONFERENCE ON CHEMISTRY AND THE ENVIRONMENT, 2023.
  19. Ribeiro, Ondina; Luís Félix; Sandra Mariza Monteiro; Cláudia Ribeiro; António Fontaínhas-Fernandes; Tiritan, Maria Elizabeth; RIBEIRO, Ana Rita Lado; Carrola, João soares. "Zebrafish Embryos (Danio rerio) as a Model for the Evaluation of Teratogenicity Caused by Toxics and Psychoactive Substances". Paper presented in 18TH INTERNATIONAL CONFERENCE ON CHEMISTRY AND THE ENVIRONMENT, 2023.
  20. Raquel Vieira; Carlos Venâncio; Luís Félix. "The effect of a stressful stimulus in behavioural, metabolic and biochemical markers in zebrafish". Paper presented in 8th Portuguese Young Chemists Meeting, 2023.
  21. Claudia Rocha; Luís Félix; Sandra Mariza Monteiro; Antunes, Luís; Carlos Venâncio; Rocha, Cláudia Alexandra; Monteiro, Sandra; Venâncio, Carlos. "Mice’s kidneys’ oxidative stress is not affected by a chronic oral administration of low-dose ketamine". Paper presented in XV Jornadas de Bioquímica, 2023.
  22. Santos, C.; Félix, Luís Manuel Lourenço; Valentim, Ana; Pinto, MLr. "Central nervous system atypical Sox 2 expression following ketamine exposure in zebrafish". Paper presented in 2ndMeeting of the Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), 2023.
  23. Ribeiro, Ondina; Ribeiro, Cláudia; Félix, Luís Manuel Lourenço; Sandra Mariza Monteiro; Carrola, João soares. "Morphometric Changes in Larval Zebrafish Exposed to Butylone". Paper presented in SETAC EUROPE 33RD ANNUAL MEETING, 2023.
  24. Ribeiro, Ondina; Pereira, Diane; Rubio, Claudia; Ribeiro, Cláudia; Luís Félix; Carrola, João soares. "Effects of Methamphetamine Exposure on the Zebrafish Embryonic Development". Paper presented in SETAC EUROPE 33RD ANNUAL MEETING, 2023.
  25. Ribeiro, Cláudia; Pérez-Pereira, Ariana; Ribeiro, Ondina; Costa, Ana; Gonçalves, Virgínia M. F.; Fernandes, Carla; Castro, Bruno B.; et al. Corresponding author: Ribeiro, Cláudia. "Enantioselectivity in Toxicity of Amphetamine, 3,4-Methylenedioxymethamphetamine and Methylenedioxypyrovalerone on Greshwater Organisms (Daphnia magna and Danio rerio)". Paper presented in SETAC EUROPE 33RD ANNUAL MEETING, 2023.
  26. Ribeiro, Cláudia; Pereira, Ariana; Ribeiro, Ondina; Costa, Ana; Gonçalves, Virgínia M. F.; Fernandes, Carla; Castro, Bruno B.; et al. "Enantioselectivity in Toxicity of Smphetamine, 3,4-Methylenedioxymethamphetamine and Methylenedioxypyrovalerone on Greshwater Organisms (Daphnia magna and Danio rerio)". Paper presented in SETAC EUROPE 33RD ANNUAL MEETING, 2023.
  27. Ribeiro, Ondina; Félix, Luís Manuel Lourenço; Ribeiro, Cláudia; Monteiro, Sandra Mariza; Carrola, João soares. "Zebrafish as a valuable vertebrate model to study teratogenicity of pharmaceuticals and psychoactive substances". Paper presented in II TOXRUN International Congress 2023, 2023.
    https://doi.org/10.48797/sl.2023.82
  28. Ribeiro, Ondina; Félix, Luís Manuel Lourenço; Ribeiro, Cláudia; Carrola, João soares. "Butylone effects on the behaviour of zebrafish (Danio rerio) larvae". Paper presented in II TOXRUN International Congress 2023, 2023.
    https://doi.org/10.48797/sl.2023.28
  29. Jorge, Sara; Félix, Luís Manuel Lourenço; Benjamín Costas; Ana M Valentim; Sara Silva Jorge; Luís Félix; Benjamin Costas Refojos; Valentim, Ana M. "ZMATRIX PROJECT - CHANGING SCIENCE AND ZEBRAFISH WELFARE ONE STEP AT A TIME". Paper presented in Beyond REMODEL: 3R models for biomedical research, 2023.
  30. Claudia Rocha; Luís Félix; Sandra Mariza Monteiro; Antunes, Luís; Carlos Venâncio. "Evaluation of oxidative stress in mice's kidneys after oral administration of chronic low-doses of ketamine". Paper presented in XXV Encontro Nacional de Estudantes de Biologia, 2023.
  31. Medeiros-Fonseca, B; Luís Félix; Carlos Venâncio; MJ Pires; Rui Medeiros; MMSM Bastos; RM. Gil da Costa ; Paula Oliveira. "Toxicological activity of Quercus ilex beverage in mice genetically modified for HPV16.". Paper presented in XV Jornadas de Genética e Biotecnologia e V Jornadas Ibéricas de Genética y Biotecnología, 2023.
  32. Beatriz Medeiros-Fonseca; Luís Félix; Carlos Venâncio; Medeiros, Rui; Costa, Rui M. Gil da; Paula Oliveira. "Pharmacological modulation of migration and neuronal differentiation of ipsc-derived neuroepithelial stem cells". Paper presented in 53rd Meeting of the Portuguese Society of Pharmacology, 41st Meeting of Clinical Pharmacology and 22nd Meeting of Toxicology, 2023.
  33. Caipira Lei, Mariana; Félix, Luís Manuel Lourenço; Silva, Severiano; Carlos Venâncio. "Ocular thermography as a non-invasive measure to assess the stress response during transport in Arouquesa breed calves". Paper presented in 1st International Congress on Veterinary and Animal Science, 2022.
  34. Martins Ribeiro, Ondina; Peixoto, Nadine; Ana Cruz; Cláudia Ribeiro; Félix, Luís Manuel Lourenço; Tiritan, Maria; Carrola, João soares. "Developmental Effects of MDMA in Zebrafish - Preliminary Data". Paper presented in SETAC Europe 32nd Annual Meeting, 2022.
  35. Dércia Santos; Ana Luzio; Félix, Luís Manuel Lourenço; MONTEIRO, SANDRA MARIZA. "Behavioural responses in zebrafish (danio rerio) to microplastics and copper exposure". Paper presented in Animal biology early career researcher symposium, 2022.
  36. Dércia Santos; Ana Luzio; Félix, Luís Manuel Lourenço; Cabecinha, Edna; Bellas, Juan; MONTEIRO, SANDRA MARIZA; Santos, Dércia; et al. "Microplastics and copper induce apoptosis, alter neurocircuits, and cause behavioral changes in zebrafish (Danio rerio) brain". Paper presented in 32nd ESCPB Congress, 2022.
    10.1016/j.ecoenv.2022.113926
  37. Jorge, Sara; A Claro; Félix, Luís Manuel Lourenço; Ana Maria Valentim. "The challenge of long duration anaesthesia for zebrafish larvae". Paper presented in FELASA 2022, 2022.
  38. Ribeiro, Ondina; Peixoto, Nadine; Cruz, Ana; Ribeiro, Cláudia; Félix, Luís Manuel Lourenço; Tiritan, Maria Elizabeth; Carrola, João soares. "Developmental effects of MDMA in zebrafish - preliminary data". Paper presented in SETAC EUROPE 32ND ANNUAL MEETING, 2022.
  39. Cruz, Ana Rita; Ribeiro, Ondina; Félix, Luís Manuel Lourenço; Ribeiro, Cláudia; Carrola, João soares. "Behavioural effects of mdma on zebrafish larvae ¿ preliminary data". Paper presented in Congress 2022 APCF-TOXRUN, 2022.
  40. Ribeiro, Ondina; Saavedra, Eduarda; Gaivão, Isabel; Luís Félix; Ribeiro, Cláudia; Tiritan, Maria Elizabeth; Carrola, João soares. "DNA damage and malformations in zebrafish exposed to psychoactive metaphedrone". Paper presented in 9th Iberoamerican Congress on Contamination and Environmental Toxicology, 2021.
  41. Caipira Lei, Mariana; Félix, Luís Manuel Lourenço; Filipa Fraga; Maria Borges; Ricardo Cardoso; MONTEIRO, SANDRA MARIZA; S Silva; Carlos Venâncio. "A termografia ocular e o stresse oxidativo na saliva como medidas não invasivas para avaliar o bem-estar de vitelos durante o transporte". Paper presented in ZOOTEC 2021 Portugal, 2021.
  42. Dércia Santos; Perez, Montse; Perez, Evaristo; LUZIO, ANA; Félix, Luís Manuel Lourenço; Sandra Mariza Monteiro; Juan Bellas Bereijo. "Acute and subchronic toxic effects of microplastics and copper, alone or combined, in blackspot seabream (Pagellus bogaraveo) larvae.". Paper presented in Aquaculture Europe, 2021.
  43. Dias, Eduarda; Ribeiro, Ondina; Isabel Gaivão; Ribeiro, Cláudia; Luís Félix; Carrola, João soares. "Comet assay for genotoxicity assessment of psychoactive substances using zebrafish embryos". Paper presented in XIII Genetics and Biotechnology Conference, 2021.
  44. T.M. Jesus; Rita Silva-Reis; Maria João Pires; G. Lanzarin; Félix, Luís Manuel Lourenço; Carlos Venâncio; Rui Gil da Costa; et al. "The anti-tumour effect of spearmint (Mentha spicata) in a HPV-16-transgenic mouse model". Paper presented in Natural products application: Health, Cosmetic and Food (Online Edition), 2021.
  45. Simone da Graça Pinto Varandas; Susana Parra; Dércia Santos; Félix, Luís; Luis Fernandes; Cabecinha, Edna; Jesús Gago; Sandra Mariza Monteiro. "Biologic effects of the heavy metal Cadmium and microplastics on Asian clam". Paper presented in 12th Symposium for European Freshwater Sciences, 2021.
  46. Diana Lopes; Félix, Luís; T. Azevedo; Dias, M.I.; L. Barros; I.C.R.F. Ferreira; T. Ferreira; et al. "A Baga de Sabugueiro como moduladora da atividade da SOD em rim de murganhos". Paper presented in XIII Encontro Nacional de Estudantes de Bioquímica, 2021.
  47. Filipa Teixeira; Félix, Luís; T. Azevedo; Dias, M.I.; L. Barros; I.C.R.F. Ferreira; T. Ferreira; et al. "Administração crónica de extrato de sabugueiro interfere com a SOD e CAT em fígado de murganho". Paper presented in XIII Encontro Nacional de Estudantes de Bioquímica, 2021.
  48. Filipa Fraga; Maria Borges; M. Lei; Sandra Mariza Monteiro; Félix, Luis; Carlos Venâncio. "O stresse oxidativo na saliva como potencial indicador de bem-estar de bovinos durante o transporte". Paper presented in XIII Encontro Nacional de Estudantes de Bioquímica, 2021.
  49. Vieira, Raquel; Germano Lanzarin; Carlos Venâncio; Félix, Luís. "Oxidative stress evaluation on thymol anaesthetised zebrafish larvae". Paper presented in 16th International Zebrafish Conference, 2021.
  50. Teresa Capriello; Félix, Luís; Sandra Mariza Monteiro; Ida Ferrandino. "Aluminium induced phenotypical alterations, apoptosis and oxidative stress in zebrafish larvae". Paper presented in 16th International Zebrafish Conference, 2021.
  51. Raquel Vieira; Carlos Venâncio; Félix, Luís. "Developmental effects of natural fungicides (Equisetum arvense, Mimosa tenuiflora, and Thymol) on zebrafish (Danio rerio)". Paper presented in Natural products application: Health, Cosmetic and Food, 2021.
  52. Megan Braga; Félix, Luís; Ana M. Coimbra. "Evaluation of genistein-induced bone and cartilage malformations in zebrafish larvae". Paper presented in XIII Jornadas de Genética e Biotecnologia, 2021.
  53. Germano Lanzarin; Raquel Vieira; Jorge Ferreira; Luís Félix; Sandra Mariza Monteiro; Carlos Venâncio. "Thymol anti-inflammatory effect: inhibition of neutrophil recruitment in a transgenic zebrafish model". Paper presented in IberPhenol, 2020.
  54. Raquel Vieira; Carlos Venâncio; Luís Félix. "Anaesthetic and biochemical responses of larval zebrafish to the monoterpene phenolic compound thymol". Paper presented in IberPhenol, 2020.
  55. Teles, Filomena; Carrola, João soares; Tiritan, Maria Elizabeth; Ribeiro, Ondina; Luís Félix; Ribeiro, Cláudia. "Ecotoxicidade enantiosseletiva da cetamina e norcetamina no peixe zebra (Danio rerio) - dados preliminares". Paper presented in 3ª Reunião Internacional da RACS, 2020.
  56. Ondina Ribeiro; Luís Félix; Cláudia Ribeiro; Mónica Quelhas Pinto; Germano Lanzarin; João Soares Carrola; Ribeiro, Ondina; et al. Corresponding author: Carrola, João soares. "Effects of venlafaxine on zebrafish larvae behaviour - preliminary results". Paper presented in SIBIC 2020, 2020.
  57. Ondina Ribeiro; Luís Félix; Cláudia Ribeiro; Hugo Ferreira; Sandra Mariza Monteiro; João Soares Carrola. "Developmental effects of venlafaxine on zebrafish – preliminary results". Paper presented in SIBIC 2020, 2020.
  58. Germano Lanzarin; Sandra Mariza Monteiro; Carlos Venâncio; Félix, Luís Manuel Lourenço. "Behavioural toxicity of environmental relevant concentrations of a glyphosate commercial formulation in zebrafish embryos". Paper presented in 11th International Symposium on Wild Fauna, 2019.
  59. Rita Correia; Ana Rita Sequeira; Félix, Luís Manuel Lourenço; Sandra Mariza Monteiro; Luis Antunes; Ana Maria Valentim; Carlos Venâncio. "Improving fish welfare in transport using MS-222 or propofol as sedative". Paper presented in 4 th AquaImprove - Aquaculture Research Workshop, 2019.
  60. Cristiana Ribeiro; Rita Correia; Ana Rita Sequeira; Félix, Luís Manuel Lourenço; Luis Antunes; Ana M. Valentim; Carlos Venâncio; et al. "Effect of tricaine mesylate (MS 222 and propofol on Nile tilapia Oreochromis niloticus gill histology after transport simulation". Paper presented in 4 th AquaImprove - Aquaculture Research Workshop, 2019.
  61. Ana Rita Sequeira; Rita Correia; Cristiana Ribeiro; Carlos Venâncio; Sandra Mariza Monteiro; Luis Antunes; Ana Maria Valentim; Félix, Luís Manuel Lourenço. "Oxidative status in the brain and liver of Nile tilapia sedated with propofol and MS-222 under simulated transport conditions". Paper presented in 4 th AquaImprove - Aquaculture Research Workshop, 2019.
  62. Diana Sousa; Raquel Vieira; Carlos Venâncio; Félix, Luís Manuel Lourenço. "Thymol and menthol as anaesthetics to aquaculture in larval zebrafish model". Paper presented in 4 th AquaImprove - Aquaculture Research Workshop, 2019.
  63. Rita Correia; Ana Rita Sequeira; Cristiana Ribeiro; Félix, Luís Manuel Lourenço; Sandra Mariza Monteiro; Luis Antunes; Ana M. Valentim. "Fish welfare: sedative effects of MS-222 and propofol under simulated transport conditions". Paper presented in 11th International Symposium on Wild Fauna, 2019.
    10.1063/1.1472187
  64. Carlos Venâncio; Raquel Vieira; Sandra Mariza Monteiro; Félix, Luís Manuel Lourenço. "Developmental and toxicological joint effects of selected fungicide mixtures in zebrafish embryo". Paper presented in EuroTox 2019, 2019.
  65. Dércia Santos; Félix, Luís Manuel Lourenço; Susana Parra; Ana Luzio; J Bellas. "Antioxidant and metal homeostasis imbalance in zebrafish (Danio rerio) early life stages co-exposed to microplastics and copper". Paper presented in SEB's Annual Meeting, 2019.
  66. Susana Parra; Félix, Luís Manuel Lourenço; Dércia Santos; Jesus Gago; Simone Varandas; Sandra Mariza Monteiro. "Antioxidant defences and lactate dehydrogenase activity in freshwater bivalve Corbicula fluminea (Bivalvia, Corbiculidea) exposed to microplastics, cadmium and their mixtures". Paper presented in SEB's Annual Meeting, 2019.
  67. Carlos Martins-Gomes; Félix, Luís Manuel Lourenço; Meriem Taghouti; Fernando M. Nunes; Amélia M. Silva. "Major phytochemicals and bioactivities of extracts from Portuguese Thymus species". Paper presented in 4th Jornadas INTERACT, 2019.
  68. Carlos Martins-Gomes; Félix, Luís Manuel Lourenço; Fernando M. Nunes; Amélia M. Silva. "Thymus carnosus Boiss: uma espécie com potencial como alimento funcional". Paper presented in Ciência e Cidadania 2019, 2019.
  69. Susana Parra; Félix, Luís Manuel Lourenço; Dércia Santos; Jesus Gago; Sandra Mariza Monteiro; Simone Varandas. "Oxidative stress response in gonads of asian clam, corbicula fluminea, simultaneouly exposed to microplastics and cadmium". Paper presented in FMCS International Freshwater Mollusk Meeting, 2018.
  70. Joana Balça-Silva; Carla Pereira Santos; Félix, Luís Manuel Lourenço; Ana M. Valentim; Maria dos Anjos Pires; C Gonçalves; Maria de Lurdes Pinto. "Effects of Ketamine Exposure In Zebrafish CNS Proliferation Capability". Paper presented in Joint ESVP and ECPV Congress, 2018.
  71. Carlos Martins-Gomes; Félix, Luís Manuel Lourenço; Fernando M. Nunes; Amélia M. Silva. "Thymus carnosus Boiss: an endangered species as a new potential functional food". Paper presented in International Conference on Medicinal Plants and Bioeconomy (ICMPB) & The 1st Sino-CPLP Symposium on Natural Products and Biodiversity Resources (SNPBR), 2018.
  72. Félix, Luís Manuel Lourenço; Tiago Coutinho; Carlos Martins-Gomes; Amélia M. Silva. "Flow cytometry study of cell cycle, apoptosis and oxidative stress of Thymus derived extracts in human colorectal cancer cell line (Caco-2)". Paper presented in International Conference on Medicinal Plants and Bioeconomy (ICMPB) & The 1st Sino-CPLP Symposium on Natural Products and Biodiversity Resources (SNPBR), 2018.
  73. Germano Lanzarin; Félix, Luís Manuel Lourenço; Dércia Santos; Carlos Venâncio; Sandra Mariza Monteiro. "Some adverse effects induced by a glyphosate-based herbicide on zebrafish embryo development". Paper presented in 11th Iberian and 8th Ibero-american Congress of Environmental Pollution and Toxicology, 2018.
  74. Susana Parra; Félix, Luís Manuel Lourenço; Dércia Santos; Jesus Gago; Simone Varandas; Sandra Mariza Monteiro. "Toxicity of microplastics, cadmium and their mixtures on Asian clam Corbicula fluminea". Paper presented in 11th Iberian and 8th Ibero-american Congress of Environmental Pollution and Toxicology, 2018.
  75. Dércia Santos; Félix, Luís Manuel Lourenço; Susana Parra; Ana Luzio; J Bellas; V Besadas; Sandra Mariza Monteiro. "Developmental toxicity of microplastics and copper, alone and in mixture, in zebrafish". Paper presented in 11th Iberian and 8th Ibero-american Congress of Environmental Pollution and Toxicology, 2018.
  76. Raquel Vieira; Rose Sousa; Sandra Mariza Monteiro; Carlos Venâncio; Félix, Luís Manuel Lourenço. "Developmental joint effects of selected fungicide mixtures in zebrafish". Paper presented in 11th Iberian and 8th Ibero-american Congress of Environmental Pollution and Toxicology, 2018.
  77. Dércia Santos; Félix, Luís Manuel Lourenço; Susana Parra; J Bellas; V Besada; Sandra Mariza Monteiro. "Effects of microplastics and copper, alone and in mixture, in zebrafish early life stages". Paper presented in SEB’s Annual Meeting, 2018.
  78. Félix, Luís Manuel Lourenço; Susana Parra; Dércia Santos; Jesus Gago; Simone Varandas; Sandra Mariza Monteiro. "Catalase biomarker response induced by microplastics, cadmium and their mixtures on exotic invasive bivalve Corbicula fluminea". Paper presented in XIX Congresso da Associação Ibérica de Limnologia, 2018.
  79. Dércia Santos; Félix, Luís Manuel Lourenço; Susana Parra; Ana Luzio; J Bellas; V Besada; Sandra Mariza Monteiro. "Microplastics and copper mixtures: A danger to aquatic early life stages?". Paper presented in II Simpósio Internacional de Águas, Solos e Geotecnologias & 3º Jornadas INTERACT, 2018.
    10.1615/ichmt.2000.thersieprocvol2.140
  80. Susana Parra; Félix, Luís Manuel Lourenço; Dércia Santos; Jesus Gago; Simone Varandas; Sandra Mariza Monteiro. "Effects of microplastics, cadmium and their mixtures on freshwater bivalve Corbicula fluminea". Paper presented in II Simpósio Internacional de Águas, Solos e Geotecnologias & 3º Jornadas INTERACT, 2018.
  81. Pinto, M. Q.; Ribeiro, Ondina; Tavares, D.; Ferreira-Cardoso, J.; Félix, Luís Manuel Lourenço; Carrola, João soares; Pinto, Mónica; Tavares, Diana; Luís Félix. "Preliminary behavioural data in Mozambique Tilapia (Oreochromis mossambicus) under the combined effect of copper sulphate and temperature". Paper presented in X International Symposium on Wild Fauna, 2017.
  82. Tiago Coutinho; Félix, Luís Manuel Lourenço; Fernando M. Nunes. "Análise do perfil polifenólico de extratos de carca de Cucurbita ficifolia Bouche". Paper presented in Ciência e Cidadania, 2017.
  83. Dércia Santos; Félix, Luís Manuel Lourenço; Susana Parra; Ana Luzio; J Bellas; V Besada; Sandra Mariza Monteiro. "Efeitos da exposição a misturas de microplásticos e cobre no sistema de defesa oxidativa de larvas de peixe-zebra, Danio rerio". Paper presented in Ciência e Cidadania, 2017.
  84. Germano Lanzarin; Félix, Luís Manuel Lourenço; Dércia Santos; Carlos Venâncio; Sandra Mariza Monteiro. "Evaluation of the Ecotoxicological Effects of Glyphosate on the Development of Zebrafish – Preliminary Results". Paper presented in Xth International Symposium on Wild Fauna (ISOWiF), 2017.
  85. Félix, L; Teixeira, I; Taghouti, M; Nunes, FM; Silva, AM. "Phytochemical profile, antioxidant activity and cytotoxicity of different extracts of Thymus vulgaris ssp. fragantissimus". Paper presented in International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, 2017.
    10.1055/s-0037-1608473
  86. Félix, L; Coutinho, T; Barejão, A; Taghouti, M; Silva, AM. "Biological activity and phytochemical analysis of extracts obtained from Santolina rosmarinifolia L.". Paper presented in 65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, 2017.
    10.1055/s-0037-1608476
  87. Inês Barejão; Félix, Luís Manuel Lourenço; Amélia M. Silva. "Estudo preliminar de extratos aquosos de Santolina Rosmarinifolia L. na viabilidade celular". Paper presented in Jornadas de Bioquímica UTAD, 2017.
  88. Tiago Coutinho; Félix, Luís Manuel Lourenço; Amélia M. Silva. "Efeito de um extrato hidro-etanólico de Santolina Rosmarinifolia L. na viabilidade celular e na atividade anti-inflamatória". Paper presented in Jornadas de Bioquímica UTAD, 2017.
  89. Isabel Teixeira; Félix, Luís Manuel Lourenço; Amélia M. Silva. "Análise da viabilidade celular e da atividade anti-inflamatória de extratos de Thymus vulgaris cv. Fragrantissims em células RAW 264.7". Paper presented in Jornadas de Bioquímica UTAD, 2017.
  90. Inês Barejão; Félix, Luís Manuel Lourenço; Amélia M. Silva. "Estudo preliminar de extratos aquosos de Santolina Rosmarinifolia L. na viabilidade celular / Preliminary study of aqueous extracts of Santolina Rosmarinifolia L. on cell viability". Paper presented in Jornadas de Bioquímica UTAD, 2017.
  91. Tiago Coutinho; Félix, Luís Manuel Lourenço; Amélia M. Silva. "Efeito de um extrato hidro-etanólico de Santolina Rosmarinifolia L. na viabilidade celular e na atividade anti-inflamatória / Effect of a hydro-ethanolic extract of Santolina Rosmarinifolia L. on cell viability and anti-inflammatory activity". Paper presented in Jornadas de Bioquímica UTAD, 2017.
  92. Isabel Teixeira; Félix, Luís Manuel Lourenço; Amélia M. Silva. "Análise da viabilidade celular e da atividade anti-inflamatória de extratos de Thymus vulgaris cv. Fragrantissims em células RAW 264.7 / analysis of cell viability and anti-inflammatory activity of extracts of Thymus vulgaris cv. Fragrantissims in RAW 264.7 cells". Paper presented in Jornadas de Bioquímica UTAD, 2017.
  93. Félix, Luís Manuel Lourenço; Luis Antunes; Ana Maria Coimbra. "The emerging use of ketamine and its implications in early vertebrate development". Paper presented in 30th ESCPB Congress, 2016.
  94. Félix, Luís Manuel Lourenço; Ana Maria Coimbra; Luis Antunes. "Ketamine changes craniofacial development in zebrafish". Paper presented in 13th FELASA congress, 2016.
  95. Margarida Monteiro; Félix, Luís Manuel Lourenço; Ana Maria Valentim. "Zebrafish as a development model for learning and anxiety alterations induced by ketamine". Paper presented in International FishMed Conference on Zebrafish Research, 2016.
  96. Ana Vidal; Félix, Luís Manuel Lourenço; Luis Antunes; Ana Maria Coimbra; Sandra Mariza Monteiro. "The use of oxidative stress biomarkers for the study of ketamine-induced toxicity in zebrafish embryos". Paper presented in XIII SECAL Congress – III SPCAL Congress, 2015.
  97. Cindy Serafim; Félix, Luís Manuel Lourenço; Luis Antunes; Manuela Matos; Ana Maria Coimbra. "Zebrafish (Danio rerio) as an important vertebrate model for the study of ketamine NMDA receptors-dependent toxicity and implementation of the 3R’s policy". Paper presented in XIII SECAL Congress – III SPCAL Congress, 2015.
  98. Félix, Luís Manuel Lourenço; Ana Vidal; Ana Maria Coimbra; Luis Antunes. "Comparative analysis of teratogenic effects of ketamine and MS-222 in zebrafish embryos". Paper presented in The AAALAC International, ESLAV and ECLAM Conference 2015, 2015.
  99. Sónia Campos; Maria de Lurdes Pinto; G. Gomes; J. Monteiro; P.G. Pinho; Félix, Luís Manuel Lourenço; Luis Antunes. "Involvement of cyp1a1 and cyp1a2 in liver and kidney biotransformation of propofol in rabbits during prolonged infusions". Paper presented in The AAALAC International, ESLAV and ECLAM Conference 2015, 2015.
  100. Cindy Serafim; Félix, Luís Manuel Lourenço; Luis Antunes; Manuela Matos; Ana Maria Coimbra. "Real time PCR analysis of NMDA receptor expression in zebrafish embryos exposed to ketamine". Paper presented in 10th Iberian and 7th Iberoamerican Conference on Environmental Contamination and Toxicology, CICTA 2015, 2015.
  101. Ana Vidal; Félix, Luís Manuel Lourenço; Luis Antunes; Ana Coimbra; Sandra Mariza Monteiro. "Short term exposure to ketamine and its oxidative stress in zebrafish development". Paper presented in 10th Iberian and 7th Iberoamerican Conference on Environmental Contamination and Toxicology, CICTA 2015, 2015.
  102. Félix, Luís Manuel Lourenço; Ana Vidal; Luis Antunes; Ana Maria Coimbra. "Exploring caspase-3 and 9 activity in ketamine-induced zebrafish embryos toxicity". Paper presented in SEB Annual Main Meeting, 2015.
  103. Félix, Luís Manuel Lourenço; Cindy Serafim; Luis Antunes; Manuela Matos; Ana Maria Coimbra. "Real time PCR analysis of apoptotic genes expression in zebrafish embryos exposed to ketamine during early development". Paper presented in SEB Annual Main Meeting, 2015.
  104. Margarida Monteiro; Félix, Luís Manuel Lourenço; Ana Maria Valentim. "Short and long term effects of ketamine exposure in the development of the animal model zebrafish first outcomes". Paper presented in Euroanaesthesia 2015, 2015.
  105. Carla Santos; Félix, Luís Manuel Lourenço; Maria Neves; Ana Coimbra; Ana M. Valentim; Luis Antunes; C. Gonçalves; Anália Carmo; Maria de Lurdes Pinto. "Refinement techniques in zebrafish anesthesia - results from a pilot study". Paper presented in International Conference on Microscopy and Microanalysis, 2014.
  106. Ana M. Valentim; Félix, Luís Manuel Lourenço; A. Carvalho; Luis Antunes. "A pilot study about alternatives for adult zebrafish anesthesia". Paper presented in HSBLAS, ESLAV and ECLAM joint scientific meeting, 2014.
  107. Félix, Luís Manuel Lourenço; Luis Antunes; Ana Coimbra. "Development time course of ketamine-induced toxicity in early zebrafish (Danio rerio) embryos". Paper presented in SEB Annual Main Meeting, 2014.
  108. Félix, Luís Manuel Lourenço; Ana Vidal; Luis Antunes; Ana Coimbra. "Oxidative stress in zebrafish embryos in different development phases after ketamine exposure". Paper presented in Seb Annual Meeting, 2014.
  109. Félix, Luís Manuel Lourenço; Cindy Serafim; Luis Antunes; Manuela Matos; Ana Coimbra. "Real time PCR analysis of shha, nog3, gstp and gclc expression in zebarfish embryos exposed to ketamine". Paper presented in SEB Annual Meeting, 2014.
  110. Félix, Luís Manuel Lourenço; Ana Coimbra; Luis Antunes. "The potential of zebrafish embryos for developing alternatives to animal anaesthesia toxicity testing". Paper presented in ESLAV, ECLAM and LAVA joint scientific meeting, 2013.
  111. Félix, Luís Manuel Lourenço; Luis Antunes; Ana Coimbra. "Oxidative stress as biomarker of ketamine-induced toxicity during early zebrafish development". Paper presented in SEB Annual Meeting, 2013.
  112. Félix, Luís Manuel Lourenço; Sandra Pereira; Sandra Mariza Monteiro; Ana Pinto; Rui Cortes; Fontainhas-Fernandes, A.; João Carrola; Ana Coimbra. "Oxidative stress in fish gill and liver use in prediction of Water Framework Directiveecological status classification". Paper presented in SEB Annual Meeting, 2013.
  113. Félix, Luís Manuel Lourenço; Ana Coimbra; Luis Antunes. "The zebrafish embryos as an alternative approach to anaesthetic animal research". Paper presented in FELASA meeting, 2013.
  114. Sónia Campos; Félix, Luís Manuel Lourenço; Carlos Venâncio; Luis Antunes; Francisco Manuel Pereira Peixoto. "Decrease of state III mitochondrial respiration by prolonged infusion of propofol ehicle in rabbit liver". Paper presented in Euroanaesthesia, 2013.
  115. Félix, Luís Manuel Lourenço; Ana Coimbra; Luis Antunes. "Ketamine-induced developmental toxicity and apoptosis in zebrafish embryos". Paper presented in Euroanaesthesia, 2013.
  116. Fernando Correia; Félix, Luís Manuel Lourenço; Teresa Summavielle; Luis Antunes; Francisco Manuel Pereira Peixoto. "Effects of graded doses of propofol in mitochondrial function in rat". Paper presented in ASA meeting, 2012.
  117. Félix, Luís Manuel Lourenço; Ana Coimbra; Luis Antunes. "Zebrafish as early safety anaesthesiology screening assay". Paper presented in ASAB/SEB/NC3Rs Symposium - Implementing the 3Rs in behavioural and physiological research, 2012.
  118. Félix, Luís Manuel Lourenço; Luis Antunes; Ana Coimbra. "Ketamine acute toxicity assessment using the zebrafish (Danio rerio) embryo toxicity test". Paper presented in SEB Annual Main Meeting, 2012.
  119. Félix, Luís Manuel Lourenço; Ana Coimbra; Luis Antunes. "Ketamine can lead to malformation of zebrafish (Danio rerio) larvae". Paper presented in Euroanaesthesia 2012, 2012.
  120. Carlos Venâncio; Félix, Luís Manuel Lourenço; Luis Antunes; Teresa Summavielle; Francisco Manuel Pereira Peixoto. "Rat liver mitochondrial impairment after ketamine chronic treatment". Paper presented in Euroanaesthesia 2012, 2012.
  121. Félix, Luís Manuel Lourenço; Ana Coimbra; Luis Antunes. "Early life stage toxicity of ketamine in Zebrafish (Danio rerio)". Paper presented in II SPCAL meeting, 2012.
  122. Pedro Pinto; Fernando Correia; Félix, Luís Manuel Lourenço; Luis Antunes; Francisco Manuel Pereira Peixoto. "Evaluation of the effect of propofol anesthesia in rat liver mitochondrial bioenergetics". Paper presented in ASA annual meeting, 2011.
  123. Carlos Venâncio; Félix, Luís Manuel Lourenço; Luis Antunes; Francisco Manuel Pereira Peixoto ; Teresa Summavielle. "Acute effects of ketamine anesthesia in brain mitochondrial function and redox state in rat". Paper presented in ASA annual meeting, 2011.
  124. Fernando Correia; Félix, Luís Manuel Lourenço; Teresa Summavielle; Luis Antunes; Francisco Manuel Pereira Peixoto. "Propofol anesthesia with lower doses interferes with brain mitochondria bioenergetics in rat". Paper presented in ASA Annual Meeting, 2011.
  125. Carlos Venâncio; Félix, Luís Manuel Lourenço; V. Almeida; Luis Antunes; Francisco Manuel Pereira Peixoto ; Teresa Summavielle; Luís M. Félix; Almeida, Vanessa; Luís Antunes. "Evaluation of mitochondrial function and redox state after ketamine anaesthesia in a rat model". Paper presented in XII Meeting of the Portuguese Society for Neuroscience, 2011.
  126. Cátia Diogo; Félix, Luís Manuel Lourenço; Sérgio Vilela; A. Burgeiro; I. Barbosa; M. Carvalho; Paulo Oliveira; Francisco Manuel Pereira Peixoto. "Mitochondrial toxicity of the phytochemicals Daphnetoxin and Daphnoretin – Relevance for possible anti-cancer application". Paper presented in International Courses on Toxicology, 2009.
  127. Sérgio Vilela; Dario Santos; Félix, Luís Manuel Lourenço; Luis Antunes; Jose Manuel Almeida; Francisco Manuel Pereira Peixoto. "Brain mitochondrial bioenergetics is differentially affected by anesthetics fentanil and remifentanil". Paper presented in 15th European Bioenergetic Conference, 2008.
  128. Francisco Manuel Pereira Peixoto ; Sérgio Vilela; Félix, Luís Manuel Lourenço; José Manuel Almeida; Luis Antunes. "The Analgesic Fentanyl Impar Oxidative Metabolism in rat brain mitochondria". Paper presented in ASA Annual Meeting, 2007.
  129. Félix, Luís Manuel Lourenço; Sérgio Vilela; Maria João Carvalho; José Almeida; Francisco Manuel Pereira Peixoto. "Assessment of daphnoretin interaction on the rat liver mitocondrial bioenergetics". Paper presented in XVth National Congress of Biochemistry, 2006.
Edited book
  1. Luís Félix. Teratogenicity Testing. Springer US. 2024.
    10.1007/978-1-0716-3625-1
  2. Félix, Luís Manuel Lourenço. Teratogenicity Testing. Springer New York. 2018.
    10.1007/978-1-4939-7883-0
Journal article
  1. Ribeiro, Ondina; Luís Félix; Ribeiro, Cláudia; Torres-Ruiz, Monica ; Tiritan, Maria Elizabeth; Gonçalves, Virgínia M. F.; Langa, Ivan; Carrola, João soares. Corresponding author: Carrola, João soares. "Unveil the toxicity induced on early life stages of zebrafish (Danio rerio) exposed to 3,4-methylenedioxymethamphetamine (MDMA) and its enantiomers". Science of The Total Environment 955 (2024): 176906. http://dx.doi.org/10.1016/j.scitotenv.2024.176906.
    Published • 10.1016/j.scitotenv.2024.176906
  2. Filipa A. Fernandes; Paula A. Oliveira; Maria L. Pinto; Carlos Venâncio; Luis Félix; Beatriz Medeiros-Fonseca; Rossana Correia; et al. "Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice". Food and Chemical Toxicology (2024): https://doi.org/10.1016/j.fct.2024.115082.
    10.1016/j.fct.2024.115082
  3. Beatriz Medeiros-Fonseca; Ana I. Faustino-Rocha; Maria João Pires; Neuparth, Maria João; Vala, Helena; Cármen Vasconcelos-Nóbrega; Gouvinhas, Irene; et al. "Exploring the therapeutic potential of Quercus ilex acorn extract in papillomavirus-induced lesions". Veterinary World 17 11 (2024): 2644-2658. https://doi.org/10.14202/vetworld.2024.2644-2658.
    Open access • Published • 10.14202/vetworld.2024.2644-2658
  4. Thiago Lopes Rocha; Luís Manuel Félix; Davi Farias. "Ecotoxicological Effects of Emerging Contaminants on Aquatic Species". Toxics (2024): https://doi.org/10.3390/toxics12080567.
    10.3390/toxics12080567
  5. Beatriz Medeiros-Fonseca; Ana I. Faustino-Rocha; Jéssica Silva; Mónica G. Silva; Maria João Pires; Maria João Neuparth; Helena Vala; et al. "Aloysia citrodora extract as a chemopreventive agent against HPV16-induced lesions: findings from K14-HPV16 mice". Exploration of Medicine (2024): https://doi.org/10.37349/emed.2024.00228.
    10.37349/emed.2024.00228
  6. Rocha, Cláudia Alexandra; Félix, Luís M.; Monteiro, Sandra Mariza; Venâncio, Carlos. "Antinociceptive Analysis of Natural Monoterpenes Eugenol, Menthol, Carvacrol and Thymol in a Zebrafish Larval Model". Pharmaceuticals 17 4 (2024): 457. http://dx.doi.org/10.3390/ph17040457.
    10.3390/ph17040457
  7. Vieira, Raquel S.F.; Sousa, Diana; Félix, Luís M.; Venâncio, Carlos A.S.. "Anaesthetic profile of thymol and menthol in zebrafish larvae model". Aquaculture and Fisheries (2024): http://dx.doi.org/10.1016/j.aaf.2024.02.001.
    10.1016/j.aaf.2024.02.001
  8. Rafael Xavier Martins; Matheus Carvalho; Maria Eduarda Maia; Bruno Flor; Terezinha Souza; Thiago Lopes Rocha; Luís M. Félix; et al. "2,4-D Herbicide-Induced Hepatotoxicity: Unveiling Disrupted Liver Functions and Associated Biomarkers". Toxics (2024): https://doi.org/10.3390/toxics12010035.
    10.3390/toxics12010035
  9. Ribeiro, Ondina; Félix, Luís; Ribeiro, Cláudia; Gonçalves, Virgínia; Tiritan, Maria Elizabeth; Soares Carrola, João. "Sublethal enantiotoxicity of MDMA on the development, teratogenicity, genotoxicity and swimming behaviour of zebrafish (Danio rerio) embryo". (2024): https://doi.org/10.48797/sl.2024.143.
    https://doi.org/10.48797/sl.2024.143
  10. Jorge, Sara; Felix, Luis; Costas, Benjamin; Valentim, Ana M.. "Advancing cortisol measurements in zebrafish: Analytical validation of a commercial ELISA kit for skin mucus cortisol". MethodsX (2024): https://publons.com/wos-op/publon/68438934/.
    10.1016/J.MEX.2024.102726
  11. Tânia Martins; Ana Filipa Matos; Joana Soares; Rúben Leite; Maria João Pires; Maria de Lurdes Pinto; Maria João Neuparth; et al. "Effects of Sulforaphane and Chlorophyl a in a Western Diet-Induced Obesity Model". Obesities (2023): https://doi.org/10.3390/obesities3040022.
    10.3390/obesities3040022
  12. Mariana Caipira Lei; Luís Félix; Ricardo Cardoso; Sandra Mariza Monteiro; Severiano Silva; Carlos Venâncio. "Non-Invasive Biomarkers in Saliva and Eye Infrared Thermography to Assess the Stress Response of Calves during Transport". Animals (2023): https://doi.org/10.3390/ani13142311.
    10.3390/ani13142311
  13. Santos, C.; Valentim, A.M.; Félix, L.; Balça-Silva, J.; Pinto, M.L.. "Longitudinal effects of ketamine on cell proliferation and death in the CNS of zebrafish". NeuroToxicology 97 (2023): 78-88. http://dx.doi.org/10.1016/j.neuro.2023.05.008.
    10.1016/j.neuro.2023.05.008
  14. Gomes, Ana; Monteiro, Sandra M.; Venâncio, Carlos; Félix, Luís. "Protective effects of 24-epibrassinolide against the 6-OHDA zebrafish model of Parkinson's disease". Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 269 (2023): 109630. http://dx.doi.org/10.1016/j.cbpc.2023.109630.
    10.1016/j.cbpc.2023.109630
  15. Germano A. B. Lanzarin; Luís M. Félix; Sandra M. Monteiro; Jorge M. Ferreira; Paula A. Oliveira; Carlos Venâncio. "Anti-Inflammatory, Anti-Oxidative and Anti-Apoptotic Effects of Thymol and 24-Epibrassinolide in Zebrafish Larvae". Antioxidants (2023): https://doi.org/10.3390/antiox12061297.
    10.3390/antiox12061297
  16. Germano A. B. Lanzarin; Luís M. Félix; António Fontaínhas-Fernandes; Sandra Mariza Monteiro; Carlos Venâncio. "Effects of Glyphosate or Glyphosate-Based Herbicide during the Zebrafish Life Cycle: A Review Addressing the Mechanisms of Toxicity". Water (2023): https://doi.org/10.3390/w15122276.
    10.3390/w15122276
  17. Pereira, Francisco; Pereira, Adriana; Monteiro, Sandra M.; Venâncio, Carlos; Félix, Luís; Venancio, Carlos; Felix, Luis. "Mitigation of nicotine-induced developmental effects by 24-epibrassinolide in zebrafish". Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 266 (2023): 109552. http://dx.doi.org/10.1016/j.cbpc.2023.109552.
    10.1016/j.cbpc.2023.109552
  18. Yu, Manyou; Gouvinhas, Irene; Pires, Maria J.; Neuparth, Maria J.; Costa, Rui M. Gil da; Medeiros, Rui; Bastos, Margarida M.S.M.; et al. "Study on the antineoplastic and toxicological effects of pomegranate (Punica granatum L.) leaf infusion using the K14-HPV16 transgenic mouse model". Food and Chemical Toxicology 174 (2023): 113689. http://dx.doi.org/10.1016/j.fct.2023.113689.
    10.1016/j.fct.2023.113689
  19. Jorge, Sara; Félix, Luís; Costas, Benjamín; Valentim, Ana M.. "Housing Conditions Affect Adult Zebrafish (Danio rerio) Behavior but Not Their Physiological Status". Animals 13 6 (2023): 1120. http://dx.doi.org/10.3390/ani13061120.
    10.3390/ani13061120
  20. Ribeiro, Ondina; Ribeiro, Cláudia; Félix, Luís; Gaivão, Isabel; Carrola, João Soares; Ribeiro, Claudia; Felix, Luis; Gaivao, Isabel; Carrola, Joao Soares. "Effects of acute metaphedrone exposure on the development, behaviour, and DNA integrity of zebrafish (Danio rerio)". Environmental Science and Pollution Research (2023): http://dx.doi.org/10.1007/s11356-023-25233-z.
    10.1007/s11356-023-25233-z
  21. Félix, Luís; Vieira, Raquel; Monteiro, Sandra M.; Venâncio, Carlos. "A meta-analytic review of monoterpene for fish anaesthesia". Fish and Fisheries (2023): http://dx.doi.org/10.1111/faf.12731.
    10.1111/faf.12731
  22. Felix, Luis; Carreira, Paulo; Peixoto, Francisco; Félix, Luís. "Effects of chronic exposure of naturally weathered microplastics on oxidative stress level, behaviour, and mitochondrial function of adult zebrafish (Danio rerio)". Chemosphere 310 (2023): 136895. https://publons.com/wos-op/publon/56117427/.
    10.1016/J.CHEMOSPHERE.2022.136895
  23. Gomes, Ana; Monteiro, Sandra M.; Venacio, Carlos; Felix, Luis. "Protective effects of 24-epibrassinolide against the 6-OHDA zebrafish model of Parkinson's disease". Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology (2023): https://publons.com/wos-op/publon/68412410/.
    10.1016/J.CBPC.2023.109630
  24. Tiago Azevedo; Tiago Ferreira; João Ferreira; Filipa Teixeira; Diana Ferreira; Rita Silva-Reis; Neuparth, MJ; et al. "Supplementation of an Anthocyanin-Rich Elderberry (Sambucus nigra L.) Extract in FVB/n Mice: A Healthier Alternative to Synthetic Colorants". Applied Sciences (2022): https://www.mdpi.com/2076-3417/12/23/11928.
    10.3390/app122311928
  25. Carneiro, Patricia; Vieira, Raquel; Venâncio, Carlos; Félix, Luís; Venancio, Carlos; Felix, Luis. "Oxidative stress as the trigger for menthol-induced developmental alterations in zebrafish (Danio rerio) model". Journal of Environmental Chemical Engineering 10 5 (2022): 108323. http://dx.doi.org/10.1016/j.jece.2022.108323.
    10.1016/j.jece.2022.108323
  26. Ferreira, Jorge M.; Jorge, Sara; Félix, Luís; Morello, Gabriela M.; Olsson, I. Anna S.; Valentim, Ana M.. "Behavioural Aversion and Cortisol Level Assessment When Adult Zebrafish Are Exposed to Different Anaesthetics". Biology 11 10 (2022): 1433. http://dx.doi.org/10.3390/biology11101433.
    10.3390/biology11101433
  27. Santos, Dércia; Luzio, Ana; Félix, Luís; Bellas, Juan; Monteiro, Sandra M.; Santos, Dercia; Felix, Luis. "Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper". Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 258 (2022): 109363. http://dx.doi.org/10.1016/j.cbpc.2022.109363.
    10.1016/j.cbpc.2022.109363
  28. Ribeiro, Ondina Martins Ribeiro; Pinto, Mónica Quelhas Pinto; Félix, Luís; Monteiro, Sandra; Fernandes, António; Carrola, João Soares Carrola. "O peixe-zebra (Danio rerio) como modelo emergente na ecotoxicologia". Revista de Ciência Elementar 10 2 (2022): http://dx.doi.org/10.24927/rce2022.021.
    10.24927/rce2022.021
  29. Ribeiro, Ondina; Félix, Luís; Ribeiro, Cláudia; Castro, Bruno; Tiritan, Maria Elizabeth; Monteiro, Sandra Mariza; Carrola, João Soares. "Enantioselective Ecotoxicity of Venlafaxine in Aquatic Organisms: Daphnia and Zebrafish". Environmental Toxicology and Chemistry 41 8 (2022): 1851-1864. http://dx.doi.org/10.1002/etc.5338.
    10.1002/etc.5338
  30. Peixoto, Nadine; Ribeiro, Ondina; Ribeiro, Cláudia; Félix, Luís; Soares Carrola, João. "Effects of MDMA on the development of Zebrafish (Danio rerio) embryos - preliminary data". RevSALUS - Revista Científica da Rede Académica das Ciências da Saúde da Lusofonia 4 Sup (2022): http://dx.doi.org/10.51126/revsalus.v4isup.266.
    10.51126/revsalus.v4isup.266
  31. Cruz, Ana Rita; Ribeiro, Ondina; Félix, Luís; Ribeiro, Cláudia; Soares Carrola, João. "Behavioural effects of MDMA on Zebrafish (Danio Rerio) Larvae: preliminary data". RevSALUS - Revista Científica da Rede Académica das Ciências da Saúde da Lusofonia 4 Sup (2022): http://dx.doi.org/10.51126/revsalus.v4isup.395.
    10.51126/revsalus.v4isup.395
  32. Ribeiro, Ondina; Gaivão, Isabel; Félix, Luís; Ribeiro, Cláudia; Soares Carrola, João. "DNA damage in zebrafish larvae induced by exposure to MDMA: preliminary data". RevSALUS - Revista Científica da Rede Académica das Ciências da Saúde da Lusofonia 4 Sup (2022): http://dx.doi.org/10.51126/revsalus.v4isup.411.
    10.51126/revsalus.v4isup.411
  33. Santos, Dércia; Perez, Montse; Perez, Evaristo; Cabecinha, Edna; Luzio, Ana; Félix, Luís; Monteiro, Sandra M.; et al. "Toxicity of microplastics and copper, alone or combined, in blackspot seabream (Pagellus bogaraveo) larvae". Environmental Toxicology and Pharmacology 91 (2022): 103835. http://dx.doi.org/10.1016/j.etap.2022.103835.
    10.1016/j.etap.2022.103835
  34. Vieira, Raquel S.F.; Venâncio, Carlos A.S.; Félix, Luís M.. "Behavioural impairment and oxidative stress by acute exposure of zebrafish to a commercial formulation of tebuconazole". Environmental Toxicology and Pharmacology 91 (2022): 103823. http://dx.doi.org/10.1016/j.etap.2022.103823.
    10.1016/j.etap.2022.103823
  35. Tânia Martins; Paula Alexandra Oliveira; Maria João Pires; Maria João Neuparth; Germano Lanzarin; Luís Félix; Carlos Venâncio; et al. "Effect of a Sub-Chronic Oral Exposure of Broccoli (Brassica oleracea L. Var. Italica) By-Products Flour on the Physiological Parameters of FVB/N Mice: A Pilot Study". Foods (2022): https://doi.org/10.3390/foods11010120.
    10.3390/foods11010120
  36. MARTINS, TÂNIA; LEITE, RÚBEN; MATOS, ANA FILIPA; SOARES, JOANA; PIRES, MARIA JOÃO; DE LURDES PINTO, MARIA; NEUPARTH, MARIA JOÃO; et al. "Beneficial Effects of Broccoli (Brassica oleracea var italica) By-products in Diet-induced Obese Mice". In Vivo 36 5 (2022): 2173-2185. http://dx.doi.org/10.21873/invivo.12943.
    10.21873/invivo.12943
  37. Lanzarin, Germano A. B.; Venancio, Carlos A. S.; Felix, Luis M.; Monteiro, Sandra M.; Lanzarin, Germano A.B.; Venâncio, Carlos A.S.; Félix, Luís M.. "Evaluation of the developmental effects of a glyphosate-based herbicide complexed with copper, zinc, and manganese metals in zebrafish". Chemosphere 308 (2022): 136430. https://publons.com/wos-op/publon/54701258/.
    10.1016/J.CHEMOSPHERE.2022.136430
  38. Ferreira, Jorge M.; Felix, Luis; Jorge, Sara; Monteiro, Sandra M.; Olsson, I. Anna S.; Valentim, Ana M.; Félix, Luís. "Anesthesia Overdose Versus Rapid Cooling for Euthanasia of Adult Zebrafish". Zebrafish 19 4 (2022): 148-159. https://publons.com/wos-op/publon/51330086/.
    10.1089/ZEB.2022.0001
  39. Ferrandino, Ida; Capriello, Teresa; Felix, Luis M.; Di Meglio, Gianluca; Santos, Dercia; Monteiro, Sandra M.; Félix, Luis M.; Santos, Dércia. "Histological alterations and oxidative stress in adult zebrafish muscle after aluminium exposure". Environmental Toxicology and Pharmacology 94 (2022): 103934. https://publons.com/wos-op/publon/54701260/.
    10.1016/J.ETAP.2022.103934
  40. Luís Félix; Rita Correia; Rita Sequeira; Cristiana Ribeiro; Sandra Monteiro; Luís Antunes; José Silva; Carlos Venâncio; Ana Valentim. "MS-222 and Propofol Sedation during and after the Simulated Transport of Nile tilapia (Oreochromis niloticus)". Biology (2021): https://doi.org/10.3390/biology10121309.
    10.3390/biology10121309
  41. Silva, Amélia M.; Félix, Luís M.; Teixeira, Isabel; Martins-Gomes, Carlos; Schäfer, Judith; Souto, Eliana B.; Santos, Dario J.; et al. "Orange thyme: Phytochemical profiling, in vitro bioactivities of extracts and potential health benefits". Food Chemistry: X 12 (2021): 100171. http://dx.doi.org/10.1016/j.fochx.2021.100171.
    10.1016/j.fochx.2021.100171
  42. Germano Lanzarin; Carlos Venâncio; Luís M. Félix; Sandra Monteiro. "Inflammatory, Oxidative Stress, and Apoptosis Effects in Zebrafish Larvae after Rapid Exposure to a Commercial Glyphosate Formulation". Biomedicines (2021): https://doi.org/10.3390/biomedicines9121784.
    10.3390/biomedicines9121784
  43. Félix, Luís; Lobato-Freitas, Carolina; Monteiro, Sandra M.; Venâncio, Carlos; Felix, Luis; Venancio, Carlos. "24-Epibrassinolide modulates the neurodevelopmental outcomes of high caffeine exposure in zebrafish (Danio rerio) embryos". Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 249 (2021): 109143. http://dx.doi.org/10.1016/j.cbpc.2021.109143.
    10.1016/j.cbpc.2021.109143
  44. Dércia Santos; Luís Félix; Ana Luzio; Susana Parra; Juan Bellas; Sandra M. Monteiro. "Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages". Chemosphere 277 (2021): 130262-130262. https://doi.org/10.1016/j.chemosphere.2021.130262.
    10.1016/j.chemosphere.2021.130262
  45. Teresa Capriello; Luis M. Félix; Sandra M. Monteiro; Dércia Santos; Rita Cofone; Ida Ferrandino. "Exposure to aluminium causes behavioural alterations and oxidative stress in the brain of adult zebrafish". Environmental Toxicology and Pharmacology 85 (2021): 103636-103636. https://doi.org/10.1016/j.etap.2021.103636.
    10.1016/j.etap.2021.103636
  46. Capriello, Teresa; Monteiro, Sandra M.; Félix, Luis M.; Donizetti, Aldo; Aliperti, Vincenza; Ferrandino, Ida; Felix, Luis M.. "Apoptosis, oxidative stress and genotoxicity in developing zebrafish after aluminium exposure". Aquatic Toxicology 236 (2021): 105872. http://dx.doi.org/10.1016/j.aquatox.2021.105872.
    10.1016/j.aquatox.2021.105872
  47. Dércia Santos; Ana Luzio; Carlos Matos; Juan Bellas; Sandra M. Monteiro; Luís Félix. "Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure". Aquatic Toxicology 235 (2021): 105814-105814. https://doi.org/10.1016/j.aquatox.2021.105814.
    10.1016/j.aquatox.2021.105814
  48. Vieira, Raquel S.F.; Venâncio, Carlos A.S.; Félix, Luís M.. "Embryonic zebrafish response to a commercial formulation of azoxystrobin at environmental concentrations". Ecotoxicology and Environmental Safety 211 (2021): 111920. http://dx.doi.org/10.1016/j.ecoenv.2021.111920.
    Published • 10.1016/j.ecoenv.2021.111920
  49. Susana Parra; Simone Varandas; Dércia Santos; Luís Félix; Lisete Fernandes; Edna Cabecinha; Jesús Gago; Sandra Mariza Monteiro. "Multi-Biomarker Responses of Asian Clam Corbicula fluminea (Bivalvia, Corbiculidea) to Cadmium and Microplastics Pollutants". Water (2021): https://doi.org/10.3390/w13040394.
    10.3390/w13040394
  50. Raquel Vieira; Carlos Venâncio; Luís Félix. "Teratogenic, Oxidative Stress and Behavioural Outcomes of Three Fungicides of Natural Origin (Equisetum arvense, Mimosa tenuiflora, Thymol) on Zebrafish (Danio rerio)". Toxics 9 1 (2021): 8-8. https://doi.org/10.3390/toxics9010008.
    10.3390/toxics9010008
  51. Félix, L.M.; Luzio, A.; Antunes, L.; Coimbra, A.M.; Valentim, A.M.. "Malformations and mortality in zebrafish early stages associated with elevated caspase activity after 24 h exposure to MS-222". Toxicology and Applied Pharmacology 412 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85099458113&partnerID=MN8TOARS.
    10.1016/j.taap.2020.115385
  52. Ferreira, Tiago; Nascimento-Goncalves, Elisabete; Macedo, Sara; Borges, Ines; Gama, Adelina; Gil da Costa, Rui M.; Neuparth, Maria J.; et al. "Toxicological and anti-tumor effects of a linden extract (Tilia platyphyllos Scop.) in a HPV16-transgenic mouse model". Food & Function 12 9 (2021): 4005-4014. https://publons.com/wos-op/publon/44407019/.
    10.1039/D1FO00225B
  53. Meriem Taghouti; Carlos Martins-Gomes; Luís M. Félix; Judith Schäfer; João A. Santos; Mirko Bunzel; Fernando M. Nunes; Amélia M. Silva. "Polyphenol composition and biological activity of Thymus citriodorus and Thymus vulgaris: Comparison with endemic Iberian Thymus species". Food Chemistry 331 (2020): 127362-127362. https://doi.org/10.1016/j.foodchem.2020.127362.
    10.1016/j.foodchem.2020.127362
  54. Lanzarin, Germano A.B.; Venâncio, Carlos A.S.; Monteiro, Sandra M.; Félix, Luís M.. "Behavioural toxicity of environmental relevant concentrations of a glyphosate commercial formulation - RoundUp® UltraMax - During zebrafish embryogenesis". Chemosphere 253 (2020): 126636. http://dx.doi.org/10.1016/j.chemosphere.2020.126636.
    10.1016/j.chemosphere.2020.126636
  55. Vieira, Raquel; Venâncio, Carlos A. S.; Félix, Luís M.. "Toxic effects of a mancozeb-containing commercial formulation at environmental relevant concentrations on zebrafish embryonic development". Environmental Science and Pollution Research (2020): http://dx.doi.org/10.1007/s11356-020-08412-0.
    10.1007/s11356-020-08412-0
  56. Pedro Rodrigues; Tiago Ferreira; Elisabete Nascimento-Gonçalves; Fernanda Seixas; Rui Miguel Gil da Costa; Tânia Martins; Maria João Neuparth; et al. "Dietary Supplementation with Chestnut (Castanea sativa) Reduces Abdominal Adiposity in FVB/n Mice: A Preliminary Study". Biomedicines 8 4 (2020): 75-75. https://doi.org/10.3390/biomedicines8040075.
    10.3390/biomedicines8040075
  57. Santos, D.; Félix, L.; Luzio, A.; Parra, S.; Cabecinha, E.; Bellas, J.; Monteiro, S.M.. "Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper". Chemosphere 261 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85088651021&partnerID=MN8TOARS.
    10.1016/j.chemosphere.2020.127748
  58. Félix, L.M.; Luzio, A.; Santos, A.; Antunes, L.M.; Coimbra, A.M.; Valentim, A.M.. "MS-222 induces biochemical and transcriptional changes related to oxidative stress, cell proliferation and apoptosis in zebrafish embryos". Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology 237 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85087124131&partnerID=MN8TOARS.
    10.1016/j.cbpc.2020.108834
  59. Fernandes, P.; Monteiro, S.M.; Venâncio, C.; Félix, L.. "24-Epibrassinolide protects against ethanol-induced behavioural teratogenesis in zebrafish embryo". Chemico-Biological Interactions 328 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85088656766&partnerID=MN8TOARS.
    10.1016/j.cbi.2020.109193
  60. Luís Félix; Ana Maria Coimbra; Ana Maria Valentim; Luís Antunes. "Review on the use of zebrafish embryos to study the effects of anesthetics during early development". Critical Reviews in Toxicology (2019): 1-14. https://doi.org/10.1080/10408444.2019.1617236.
    10.1080/10408444.2019.1617236
  61. Lanzarin, Germano A. B.; Félix, Luís M.; Santos, Dércia; Venâncio, Carlos A. S.; Monteiro, Sandra M.. "Dose-dependent effects of a glyphosate commercial formulation – Roundup® UltraMax - on the early zebrafish embryogenesis". Chemosphere (2019): http://dx.doi.org/10.1016/j.chemosphere.2019.02.071.
    10.1016/j.chemosphere.2019.02.071
  62. Venancio, C.; Vieira, R.; Monteiro, S. M.; Felix, L.. "Developmental and toxicological joint effects of selected fungicide mixtures in zebrafish embryo". Toxicology Letters (2019): https://publons.com/wos-op/publon/31204367/.
  63. Luís M. Félix; Ana Luzio; Maria Themudo; Luís Antunes; Manuela Matos; Ana M. Coimbra; Ana M. Valentim. "MS-222 short exposure induces developmental and behavioural alterations in zebrafish embryos". Reproductive Toxicology 81 (2018): 122-131. https://doi.org/10.1016/j.reprotox.2018.07.086.
    10.1016/j.reprotox.2018.07.086
  64. Luís M. Félix; Ana M. Vidal; Cindy Serafim; Ana M. Valentim; Luís M. Antunes; Sandra M. Monteiro; Manuela Matos; Ana M. Coimbra. "Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish (Danio rerio) embryos". Chemosphere 201 (2018): 730-739. https://doi.org/10.1016/j.chemosphere.2018.03.049.
    10.1016/j.chemosphere.2018.03.049
  65. Martins, Tânia; Diniz, Enoque; Félix, Luís M.; Antunes, Luís. "Evaluation of anaesthetic protocols for laboratory adult zebrafish (Danio rerio)". PLOS ONE 13 5 (2018): e0197846. http://dx.doi.org/10.1371/journal.pone.0197846.
    10.1371/journal.pone.0197846
  66. Medeiros-Fonseca, B.; Mestre, V. F.; Colaço, B.; Pires, M. J.; Martins, T.; Gil da Costa, R. M.; Neuparth, M. J.; et al. "Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice". Food & Function 9 8 (2018): 4419-4428. http://dx.doi.org/10.1039/c8fo00783g.
    10.1039/c8fo00783g
  67. Taghouti, M.; Martins-Gomes, C.; Schäfer, J.; Félix, L.M.; Santos, J.A.; Bunzel, M.; Nunes, F.M.; et al. "Thymus pulegioides L. as a rich source of antioxidant, anti-proliferative and neuroprotective phenolic compounds". Food and Function 9 7 (2018): 3617-3629. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050569468&partnerID=MN8TOARS.
    10.1039/c8fo00456k
  68. Felix, Luis. "Teratogenicity Testing Methods and Protocols Preface". Methods in Molecular Biology (2018): https://publons.com/wos-op/publon/31204370/.
  69. Félix, L.M.; Serafim, C.; Valentim, A.M.; Antunes, L.M.; Matos, M.; Coimbra, A.M.. "Apoptosis-related genes induced in response to ketamine during early life stages of zebrafish". Toxicology Letters 279 (2017): 1-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-85025172761&partnerID=MN8TOARS.
    10.1016/j.toxlet.2017.07.888
  70. Félix, L.; Oliveira, M.M.; Videira, R.; Maciel, E.; Alves, N.D.; Nunes, F.M.; Alves, A.; et al. "Carvedilol exacerbate gentamicin-induced kidney mitochondrial alterations in adult rat". Experimental and Toxicologic Pathology 69 2 (2017): 83-92. http://www.scopus.com/inward/record.url?eid=2-s2.0-85007494763&partnerID=MN8TOARS.
    10.1016/j.etp.2016.11.006
  71. Félix, L.M.; Antunes, L.M.; Coimbra, A.M.; Valentim, A.M.. "Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine". Psychopharmacology 234 4 (2017): 549-558. http://www.scopus.com/inward/record.url?eid=2-s2.0-85001555685&partnerID=MN8TOARS.
    10.1007/s00213-016-4491-7
  72. Félix, L.M.; Correia, F.; Pinto, P.A.; Campos, S.P.; Fernandes, T.; Videira, R.; Oliveira, M.M.; Peixoto, F.P.; Antunes, L.M.. "Propofol affinity to mitochondrial membranes does not alter mitochondrial function". European Journal of Pharmacology 803 (2017): 48-56. http://www.scopus.com/inward/record.url?eid=2-s2.0-85016999873&partnerID=MN8TOARS.
    10.1016/j.ejphar.2017.03.044
  73. Félix, L.M.; Serafim, C.; Martins, M.J.; Valentim, A.M.; Antunes, L.M.; Matos, M.; Coimbra, A.M.. "Morphological and behavioral responses of zebrafish after 24 h of ketamine embryonic exposure". Toxicology and Applied Pharmacology 321 (2017): 27-36. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013752088&partnerID=MN8TOARS.
    10.1016/j.taap.2017.02.013
  74. Félix, L.M.; Serafim, C.; Valentim, A.M.; Antunes, L.M.; Campos, S.; Matos, M.; Coimbra, A.M.. "Embryonic Stage-Dependent Teratogenicity of Ketamine in Zebrafish (Danio rerio)". Chemical Research in Toxicology 29 8 (2016): 1298-1309. http://www.scopus.com/inward/record.url?eid=2-s2.0-84982279770&partnerID=MN8TOARS.
    10.1021/acs.chemrestox.6b00122
  75. Campos, S.; Félix, L.; Venâncio, C.; de Lurdes Pinto, M.; Peixoto, F.; de Pinho, P.G.; Antunes, L.. "In vivo study of hepatic oxidative stress and mitochondrial function in rabbits with severe hypotension after propofol prolonged infusion". SpringerPlus 5 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84983089100&partnerID=MN8TOARS.
    10.1186/s40064-016-2970-2
  76. Dinis, L.-T.; Bernardo, S.; Conde, A.; Pimentel, D.; Ferreira, H.; Félix, L.; Gerós, H.; Correia, C.M.; Moutinho-Pereira, J.. "Kaolin exogenous application boosts antioxidant capacity and phenolic content in berries and leaves of grapevine under summer stress". Journal of Plant Physiology 191 (2016): 45-53. http://www.scopus.com/inward/record.url?eid=2-s2.0-84950272040&partnerID=MN8TOARS.
    10.1016/j.jplph.2015.12.005
  77. Félix, L.M.; Vidal, A.M.; Serafim, C.; Valentim, A.M.; Antunes, L.M.; Campos, S.; Matos, M.; Monteiro, S.M.; Coimbra, A.M.. "Ketamine-induced oxidative stress at different developmental stages of zebrafish (Danio rerio) embryos". RSC Advances 6 66 (2016): 61254-61266. http://www.scopus.com/inward/record.url?eid=2-s2.0-84976869545&partnerID=MN8TOARS.
    10.1039/c6ra08298j
  78. Campos, S.; Monteiro, J.; Valenzuela, B.; Gonçalinho, H.; de Pinho, P.G.; Fresco, P.; Félix, L.; Antunes, L.. "Evidence of Different Propofol Pharmacokinetics under Short and Prolonged Infusion Times in Rabbits". Basic and Clinical Pharmacology and Toxicology 118 6 (2016): 421-431. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964735393&partnerID=MN8TOARS.
    10.1111/bcpt.12521
  79. Valentim, A.M.; Félix, L.M.; Carvalho, L.; Diniz, E.; Antunes, L.M.. "A new anaesthetic protocol for adult zebrafish (Danio rerio): Propofol combined with lidocaine". PLoS ONE 11 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84959205162&partnerID=MN8TOARS.
    10.1371/journal.pone.0147747
  80. Campos, S.P.; de Lurdes Pinto, M.; Gomes, G.; de Pinho, P.G.; Monteiro, J.A.; Félix, L.M.; Branco, P.S.; Ferreira, L.M.; Antunes, L.M.. "Expression of CYP1A1 and CYP1A2 in the liver and kidney of rabbits after prolonged infusion of propofol". Experimental and Toxicologic Pathology 68 9 (2016): 521-531. http://www.scopus.com/inward/record.url?eid=2-s2.0-84994850593&partnerID=MN8TOARS.
    10.1016/j.etp.2016.07.006
  81. Venâncio, C.; Félix, L.; Almeida, V.; Coutinho, J.; Antunes, L.; Peixoto, F.; Summavielle, T.. "Acute ketamine impairs mitochondrial function and promotes superoxide dismutase activity in the rat brain". Anesthesia and Analgesia 120 2 (2015): 320-328. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922337300&partnerID=MN8TOARS.
    10.1213/ANE.0000000000000539
  82. Félix, Luís M.; Antunes, Luís M.; Coimbra, Ana M.. "Ketamine NMDA receptor-independent toxicity during zebrafish (Danio rerio) embryonic development". Neurotoxicology and Teratology 41 (2014): 27-34.
    Published • 10.1016/j.ntt.2013.11.005
  83. Campos, Sónia; Monteiro, J.; Antunes, L.; Branco, S. P.; Ferreira, L. M.; Félix, L.; Pinho, P. G.. "Simultaneous Quantification of Propofol and its Non-Conjugated Metabolites in Several Biological Matrices Using Gas Chromatography/Ion Trap – Mass Spectrometry Method". Journal of Analytical & Bioanalytical Techniques 5 3 (2014): 1-9.
    Published • 10.4172/2155-9872.1000195
  84. Oliveira, Maria M.; Teixeira, José C.; Vasconcelos-Nóbrega, Cármen; Felix, Luis M.; Sardão, Vilma A.; Colaço, Aura A.; Oliveira, Paula A.; Peixoto, Francisco P.. "Mitochondrial and liver oxidative stress alterations induced by N -butyl- N -(4-hydroxybutyl)nitrosamine: relevance for hepatotoxicity". Journal of Applied Toxicology 33 6 (2013): 434-443.
    Published • 10.1002/jat.1763
  85. Venâncio, C.; Antunes, L.; Félix, L.; Rodrigues, P.; Summavielle, T.; Peixoto, F.. "Chronic ketamine administration impairs mitochondrial complex i in the rat liver". Life Sciences 93 12-14 (2013): 464-470. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884202630&partnerID=MN8TOARS.
    10.1016/j.lfs.2013.08.001
  86. Vilela, Sérgio M.F.; Santos, Dario J.S.L.; Félix, Luis; Almeida, José M.; Antunes, Luis; Peixoto, Francisco. "Are fentanyl and remifentanil safe opioids for rat brain mitochondrial bioenergetics?". Mitochondrion 9 4 (2009): 247-253.
    Published • 10.1016/j.mito.2009.03.002
  87. Diogo, Cátia V.; Félix, Luís; Vilela, Sérgio; Burgeiro, Ana; Barbosa, Inês A.; Carvalho, Maria J.M.; Oliveira, Paulo J.; Peixoto, Francisco P.. "Mitochondrial toxicity of the phyotochemicals daphnetoxin and daphnoretin – Relevance for possible anti-cancer application". Toxicology in Vitro 23 5 (2009): 772-779.
    Published • 10.1016/j.tiv.2009.04.002
  88. Vilela, Sergio M.; Santos, Dario L.; Felix, Luis M.; Antunes, Luis M.; Almeida, L. Jose M.; Peixoto, Francisco M.. "Brain mitochondrial bioenergetics is differentially affected by anesthetics fentanil and remifentanil". Biochimica et Biophysica Acta (BBA) - Bioenergetics (2008): https://publons.com/wos-op/publon/3465907/.
    10.1016/J.BBABIO.2008.05.198
Journal issue
  1. Félix, Luís Manuel Lourenço; Valentim, Ana M; Carlos Venâncio. "Research Topic: Efficacy and effects of aquatic animal anaesthesia". Frontiers in Veterinary Science (2024): https://www.frontiersin.org/research-topics/60921/efficacy-and-effects-of-aquatic-animal-anaesthesia.
    Under revision
  2. "Ecotoxicology and Environmental Health of Pharmaceuticals and Personal Care Products". International Journal of Environmental Research and Public Health (2022):
    Under revision • Invited editor
  3. Félix, Luís Manuel Lourenço. "Molecular Oxidative Markers of Medicinal Drugs". International Journal of Environmental Research and Public Health (2021): https://www.mdpi.com/journal/ijerph/special_issues/Molecular_Oxidative_Markers_Medicina_Drugs#editors.
    Under revision • Invited editor
Newspaper article
  1. Luís Félix. "Promoção do bem-estar em investigação", VivaDouro, 2024, https://www.vivadouro.org/noticias/promocao-do-bem-estar-em-investigacao.
Online resource
  1. Santos, Dércia; Perez, Montse; Perez, Evaristo; Cabecinha, Edna; LUZIO, ANA; Luís Félix; Sandra Mariza Monteiro; Juan Bellas Bereijo. Pagellus bogaraveo proliferating cell nuclear antigen mRNA, partial cds. 2022. https://www.ncbi.nlm.nih.gov/nuccore/MZ464023.1.
  2. Santos, Dércia; Perez, Montse; Perez, Evaristo; Cabecinha, Edna; LUZIO, ANA; Félix, Luís Manuel Lourenço; Sandra Mariza Monteiro; Juan Bellas Bereijo. Pagellus bogaraveo actin mRNA, partial cds. 2022. https://www.ncbi.nlm.nih.gov/nuccore/MZ464020.1.
Preprint
  1. Sara Jorge; Luís Félix; Benjamín Costas; Ana M Valentim; Jorge, Sara; Félix, Luís; Costas, Benjamín; Valentim, Ana M.. "Housing conditions affect adult zebrafish (Danio rerio) behavior but not their physiological status". 2023. https://doi.org/10.1101/2023.02.10.528020.
    10.1101/2023.02.10.528020
Thesis / Dissertation
  1. Félix, Luís Manuel Lourenço. "Towards an understanding of ketamine teratogenicity in zebrafish early development". PhD, Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, 2016. http://hdl.handle.net/10348/7301.
  2. Félix, Luís Manuel Lourenço. "Avaliação da acção do carvedilol na nefrotoxicidade induzida por gentamicina em rato". Master, Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, 2009.
  3. Félix, Luís Manuel Lourenço. "Avaliação da acção da Daphnoretina na Bioenergética Mitocondrial e na Morte Celular". Degree, 2007.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024 Monoterpenes as sedatives and stress-reducing agents in zebrafish Harvesting Knowledge
2024 Behaviour as key to improve laboratory zebrafish welfare: a tale from environmental enrichment and analgesia 2nd Regional Meeting of ISAE South West Europe
2024 Navigating into the 2R's of zebrafish research: Refinement and Reduction examples Portuguese Society for Laboratory Animals (SPCAL) meeting
2023 Effects of MDMA on the development of zebrafish (Danio rerio) embryos - Preliminary data Congress 2022 APCF-TOXRUN
2022/01/27 The use of Propofol and MS-222 to transport live fish - the tilapia model ZEBREFINE - refinement opportunities for zebrafish anaesthesia
2022 Behavioural responses in zebrafish (Danio rerio) to microplastics and copper exposure Animal biology early career researcher symposium
2021 Effects of chronic exposure of microplastics and nanoplastics on oxidative stress level, behavior and mitochondrial function of adult zebrafish (Danio rerio) CICTA - 9º Iberoamerican Congress on Contamination and Environmetal Toxicology
2021 Anaesthetic Profile and Biochemical Effects of Thymol and Menthol in Zebrafish Model Aquaculture Europe 2021
2021 Utilização de larvas de peixe-zebra como modelo alternativo para avaliação da toxicidade do mentol enquanto composto anestésico III Jornadas Ibéricas de Toxicologia
2021 Efeito do Sulforafano no stresse oxidativo hepático num modelo animal de obesidade III Jornadas Ibéricas de Toxicologia
2021 Avaliação de parâmetros de stresse oxidativo hepático após administração da baga de sabugueiro em murganhos III Jornadas Ibéricas de Toxicologia
2021 Efeito da baga do sabugueiro no rim de murganho: Avaliação do stresse oxidativo III Jornadas Ibéricas de Toxicologia
2019 Toxicologia: O peixe-zebra como modelo emergente Semana da Ciência e Tecnologia
Universidade de Trás-os-Montes e Alto Douro (Vila Real, Portugal)
2018 Exploring bioactivities of Thymus species extracts in search of new sources of nutraceuticals International Conference on Medicinal Plants and Bioeconomy (ICMPB) & The 1st Sino-CPLP Symposium on Natural Products and Biodiversity Resources (SNPBR)
2018 A study on the in vitro enzyme inhibitory properties of extracts obtained from selected species from Lamiaceae and Asteraceae family Simpósio Internacional de Águas, Solos e Geotecnologias
2018 Alterações climáticas e o impacto da utilização de fungicidas no desenvolvimento embrionário de peixe-zebra Congresso Nacional sobre Alterações Climáticas
2017 Avaliação da toxicidade de fungicidas sintéticos e naturais aplicados na agricultura usando embriões de peixe zebra Ciência e Cidadania
2017 Chemical composition, antiradicalar capacity and antiproliferative activity of extracts obtained from selected species from Lamiaceae and Asteraceae family 2nd Interact Journeys UTAD
2017 Utilização de embriões de peixe-zebra como modelo em ciências biológicas IX Jornadas de Genética
Universidade de Trás-os-Montes e Alto Douro
2016 Teratogenicidade da cetamina em fases iniciais do desenvolvimento do peixe-zebra X Jornadas de Bioquímica UTAD
2015 Screening of plant extracts for biological activity: Focus on Lamiaceae family 1st Interact Journeys UTAD
2015 Developmental impairment following chronic exposure to ketamine in early zebrafish (Danio rerio) embryos 10th Iberian and 7th Iberoamerican Conference on Environmental Contamination and Toxicology
2014 New anaesthesia protocols in zebrafish – pilot study GV-SOLAS Annual Meeting
2012 Study of ketamine toxicity in zebrafish development VI Jornadas de Bioquímica UTAD
2011 Propofol anaesthesia: neurotoxic and hepatotoxic effects IV Jornadas de Bioquímica UTAD
2010 Possible anti-cancer application of the phytochemicals daphnetoxin and daphnoretin-relevance of mitochondrial toxicity 44th Annual Meeting of the European Society for Clinical investigation
2009 Protective effects of B-blocker carvedilol on gentamicin-induced nephrotoxicity in the rat International Courses on Toxicology
2007 Cytotoxicity of daphnoretin on mouse K1735-M2 melanoma cells - Are mitochondrial effects relevant? XXXVIII annual meeting of the Portuguese Pharmacological Society, XXIV meeting of Clinical Pharmacology, VII Toxicology meeting
2007 Inneficacy of daphnetoxin as an effective anti-proliferative agent on a metastatic mouse melanoma cell line XXXVIII annual meeting of the Portuguese Pharmacological Society, XXIV meeting of Clinical Pharmacology, VII Toxicology meeting
2007 The mitochondria: an important target for toxicants I Jornadas Cientificas do CECAV UTAD

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024 - Current Avaliação do impacto de uma exposição crónica do glifosato sobre os complexos mitocondriais no intestino do peixe-zebra (Danio rerio)
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2024 - Current Impacto de monoterpenos no stresse oxidativo hepático de peixe-zebra (Danio rerio) sujeito a um transporte simulado
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2024 - Current Investigação do papel dos monoterpenos no stress oxidativo renal de peixe-zebra (Danio rerio) sob transporte simulado
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2024 - Current Impacto de monoterpenos nos parâmetros metabólicos de peixe-zebra (Danio rerio) após transporte simulado
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2024 - Current Impacto de monoterpenos no transporte de peixe-zebra (Danio rerio): uma abordagem integrada de técnicas bioquímicas, fisiológicas e comportamentais
Supervisor
 Bioquímica (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2023 - Current Efeitos de um inibidor sintético da LRRK2 na doença de Parkinson usando modelo de peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022 - Current Enantioselective aquatic and terrestrial ecotoxicity and bioaccumulation of new psychoactive substances in zebrafish and earthworms
Co-supervisor
2021 - Current Establishment of different matrices to measure cortisol in zebrafish under acute and chronic stressful situations
Co-supervisor
 Ciências Veterinárias (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/01/01 - Current Anaesthetic efficiency and biochemical effects of thymol and menthol for improving well-being in aquaculture using zebrafish model
Supervisor
 Ciências Químicas e Biológicas (PhD)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2024 - 2024 Avaliação imunohistoquímica e biomarcadores celulares de um inibidor sintético da LRRK2 na doença de Parkinson usando modelo de peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2024 - 2024 Avaliação dos efeitos combinados de microplásticos e cobre no intestino de peixe-zebra (Danio rerio)
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2024 - 2024 Expressão do Nrf2 e biomarcadores celulares em peixe-zebra (Danio rerio) após exposição embrionária a um extrato de Aloe vera
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2024 - 2024 Avaliação dos efeitos combinados de microplásticos e cobre na gónada de peixe-zebra (Danio rerio)
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2023 - 2024 Análise de efeitos teratogénicos de extrato de aloé vera em embriões de peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023 - 2024 Avaliação da ingestão conjunta de Cyperus esculentus e Adansonia digitata no stresse oxidativo hepático de murganhos
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023 - 2024 Análise do efeito da exposição oral ao rizoma de Pteridium aquilinum na carcinogénese viral no modelo animal K14HPV16
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022 - 2024 Efeitos cerebrais da administração oral de cetamina em murganhos
Supervisor
 Biologia Clínica Laboratorial (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2023 - 2023 Avaliação dos efeitos analgésicos de monoterpenos fenólicos em peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2023 - 2023 Avaliação dos efeitos de um extrato de película de amêndoa num modelo de doença neurológica induzida em peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2023 - 2023 Avaliação dos efeitos combinado de microplásticos e cobre no cérebro de peixe-zebra (Danio rerio)
Co-supervisor
 Genética e Biotecnologia (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023 - 2023 Avaliação dos efeitos de microplásticos no fígado de peixe-zebra (Danio rerio)
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2022 - 2022 Efeitos de extratos de película de amêndoa na inflamação e stresse oxidativo induzidos por cobre em larvas de peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022 - 2022 Avaliação dos efeitos de um brassinosteroide num modelo de doença neurológica induzida em peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022 - 2022 Avaliação do stresse oxidativo hepático após administração de doses analgésicas de cetamina em murganho
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2022 - 2022 A qualidade da Carne Arouquesa: proteção antioxidante, caracterização histológica da gordura e tipificação das fibras do músculo semitendinoso
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2021 - 2022 Efeito dos metais cobre, magnésio, manganês, selénio e zinco nos parâmetros de stresse oxidativo do músculo longuíssimo torácico: a sua importância na alimentação
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021 - 2022 O stresse oxidativo no músculo semitendinoso de vitela e a sua relação com os metais alumínio, cádmio, chumbo e ferro: consequências da sua utilização alimentar
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021 - 2022 Efeito da administração intranasal de vanádio no stresse oxidativo hepático utilizando o rato como modelo animal
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2020 - 2022 Efeito da flor de brócolo, sulforafano e clorofila no stresse oxidativo hepático num modelo de obesidade
Co-supervisor
 Engenharia Alimentar (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2018/01 - 2022 Avaliação dos efeitos da associação do glifosato com os metais cobre, zinco e manganês no desenvolvimento do peixe-zebra
Co-supervisor
 Ciências Químicas e Biológicas (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2021 - 2021 Efeitos moduladores de um brassinosteroide contra a toxicidade induzida por nicotina em embrião de peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021 - 2021 Avaliação dos efeitos anti-inflamatórios de alguns compostos naturais em peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021 - 2021 O stress oxidativo e a sua relação com os níveis de cortisol, ambos avaliados na saliva de bovinos após transporte
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021 - 2021 Avaliação do bem-estar animal utilizando biomarcadores de stresse oxidativo na saliva de vitelos
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021 - 2021 Efeito da baga de sabugueiro no rim de murganho: avaliação do stresse oxidativo
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021 - 2021 O stresse oxidativo como biomarcador da toxicidade hepática da baga de sabugueiro em murganhos
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2020 - 2021 Ecotoxicidade enantiosseletiva da venlafaxina em organismos aquáticos: algas, protozoários, dáfnias e peixe zebra
Co-supervisor
 Biologia Clínica Laboratorial
Universidade de Trás-os-Montes e Alto Douro, Portugal
2020 - 2021 Efeitos do mentol no desenvolvimento do embrião de peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2020 - 2021 Avaliação do stresse oxidativo induzido por anestésicos durante o transporte simulado de larvas de peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2020 - 2020 Efeitos moduladores de um brassinosteroide contra a toxicidade induzida por nicotina em embrião de peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2020 - 2020 Estudo da expressão dos recetores de estrogénio e do ácido retinóico e avaliação do desenvolvimento de estruturas ósseas em embriões de peixe-zebra expostos a um fito estrogénio
Co-supervisor
 Genética e Biotecnologia (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2020 - 2020 Avaliação dos efeitos da exposição a genisteina no desenvolvimento embrionário e na expressão de fatores de transcrição reguladores da adipogénese em peixe-zebra
Co-supervisor
 Genética e Biotecnologia (Degree)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2020 - 2020 Avaliação das alterações celulares induzidas por anestésicos durante o transporte simulado de larvas de peixe-zebra
Supervisor
 Biologia (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2019 - 2020 Avaliação dos efeitos tóxicos do mentol no desenvolvimento e comportamento de larvas de peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2019 - 2019 Efeitos moduladores de um Brassinosteróide contra a toxicidade induzida por cafeína em embrião de peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2019 - 2019 Efeitos moduladores de um brassinosteroide contra a toxicidade induzida por um agente neurotóxico em embrião de peixe-zebra
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2019 - 2019 Efeitos da exposição crónica de microplásticos ao nível de stresse oxidativo, comportamento e função mitocondrial de peixe zebra adulto (Danio rerio)
Supervisor
 Bioquímica (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2019 - 2019 Avaliação de diferentes anestésicos para transporte de animais produzidos em aquacultura
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2018 - 2018 O efeito de um Brassinoesteroide na toxicidade induzida no embrião de peixe-zebra pela exposição a agente teratogénico
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2017 - 2018 Effects of synthetic and plant-based fungicides on biomarkers in the early stages of zebrafish development
Supervisor
 Bioquímica (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2017 - 2017 Efeito de extratos aquosos de Santolina rosmarinifolia L. na viabilidade celular e na atividade anti-inflamatória
Supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2017 - 2017 Efeito de um extrato hidro-etanólico de Santolina rosmarinifolia L. na viabilidade celular e na atividade anti-inflamatória
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2017 - 2017 Extratos de plantas da família Lamiaceae ricos em polifenóis: estudos in vitro perspetivando aplicações biomédicas
Co-supervisor
 Engenharia Biomédica (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2016 - 2016 Implementação de novos protocolos anestésicos em peixe-zebra
Co-supervisor
 Medicina Veterinária (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2015 - 2015 Avaliação do stresse oxidativo por exposição a cetamina no desenvolvimento embrionário de peixe-zebra
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2014 - 2014 Avaliação do antígeno nuclear de proliferação celular em embriões de peixe-zebra expostos a cetamina
Co-supervisor
 Bioquímica (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2024/11/19 - 2024/11/19 O peixe-zebra como modelo para o bem-estar animal e a sustentabilidade ambiental (2024/11/19)
Workshop (Co-organisor)
 Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2024/05/16 - 2024/05/16 Desenvolvimento embrionário em peixe-zebra: um modelo sustentável para a monitorização ambiental (2024/05/16)
Workshop (Co-organisor)
 Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2024/03/13 - 2024/03/13 Zebrafish as an alternative model for toxicology (2024/03/13)
Workshop
 Universidade de Trás-os-Montes e Alto Douro, Portugal
2022/04/24 - 2022/04/24 O peixe-zebra como modelo alternativo para toxicologia (2022/04/24 - 2022/04/24)
Workshop
2022/01/27 - 2022/01/27 Member of the Organising Committee of the ZEBREFINE online meeting (2022/01/27 - 2022/01/27) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020 - 2020 Curso Prático - Aplicação de modelos biológicos a estudos de ecotoxicologia (2020 - 2020)
Workshop (Other)
 Universidade de Trás-os-Montes e Alto Douro, Portugal
2016 - 2016 Member of the Local Organising team of the “Jornadas de Bioquímica” 2016 (2016 - 2016) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2015 - 2015 Member of the Local Organising team of the “Jornadas de Bioquímica” 2015 (2015 - 2015) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2014 - 2014 Member of the Local Organising team of the “Jornadas de Bioquímica” 2014 (2014 - 2014) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2013 - 2013 Member of the Local Organising team of the “Olimpíadas de Química Júnior” 2013 (2013 - 2013) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2013 - 2013 Member of the Local Organising team of the “Jornadas de Bioquímica” 2013 (2013 - 2013) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2012 - 2012 Member of the Local Organising team of the “Olimpíadas de Química Júnior” 2012 (2012 - 2012) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2012 - 2012 Member of the Local Organising team of the “Jornadas de Bioquímica” 2012 (2012 - 2012) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2011 - 2011 Member of the Local Organising team of the “Olimpíadas de Química Júnior” 2011 (2011 - 2011) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2011 - 2011 Member of the Local Organising team of the “Jornadas de Bioquímica” 2011 (2011 - 2011) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2010 - 2010 Member of the Local Organising team of the “Jornadas de Bioquímica” 2010 (2010 - 2010) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2009 - 2009 Member of the Local Organising team of the “Jornadas de Bioquímica” 2009 (2009 - 2009) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2008 - 2008 Member of the Local Organising team of the “Olimpíadas de Química Júnior” 2008 (2008 - 2008) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2006 - 2006 Member of the Local Organising team of the “Olimpíadas de Química Júnior” 2006 (2006 - 2006) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2024/11/12 - 2024/11/13 2nd Edition of the Animal Health Symposium
Symposium
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2024/09/04 - 2024/09/04 Swimming into refinement: stress and pain management in laboratory zebrafish
Seminar
2024/05/10 - 2024/05/10 II Ciclo de Encontros: Utilização de Animais com Fins Experimentais
Seminar
Universidade de Trás-os-Montes e Alto Douro Centro de Ciência Animal e Veterinária, Portugal
2023/05/16 - 2023/05/16 Session Moderator
Conference
 XV Jornadas de Bioquímica
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023/05/16 - 2023/05/16 Round table old students
Round table
 XV Jornadas de Bioquímica
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021/10/13 - 2021/10/13 Simple steps to publication-quality western blots
Seminar
Thermo Fisher Scientific Inc Pittsburgh, United States
2021/02/23 - 2021/02/23 Focus on Fish: Practical refinements for fishes in research and testing
Seminar
Royal Society for the Prevention of Cruelty to Animals, United Kingdom
2019/02/04 - 2019/02/05 FishInspector Training Workshop
Workshop
Helmholtz-Zentrum für Umweltforschung UFZ, Germany
2014/11/07 - 2014/11/07 Improving Zebrafish Husbandry towards better research and animal welfare
Workshop
Centro Champalimaud, Portugal
2012/01/09 - 2012/01/13 Animal ethics - From Laboratory toWilderness
Seminar
Eesti Maaülikooli, Estonia
2011/10/19 - 2011/10/21 FRAME's training schools in Experimental Design and Statistical Analysis of Biomedical Experiments
Seminar
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2006/07/03 - 2006/07/05 2nd Scanning Electron Microscopy Course
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2024 Determinação de compostos bioativos e atividade antioxidante em Giesta Branca (Cytisus multiflorus)
(Thesis) Main arguer
 Ricardo Jorge Barbosa Lopes (Other)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022 Efeito das substâncias psicoativas no comportamento de larvas de peixe-zebra (Dario rerio)
(Thesis) Main arguer
 Ana Rita Amaral Teixeira Gonçalves da Cruz (Other)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2022 Efeito das substâncias psicoativas no desenvolvimento de larvas de peixe-zebra (Dario rerio)
(Thesis) Main arguer
 Nadine Almeida Peixoto (Other)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2021 O bem-estar animal durante o transporte em aquacultura: Avaliação do efeito da sedação em Tilápia do Nilo
(Thesis) Main arguer
 Rita Correia (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021 Utilização de óleo de cravinho como anestésico em peixe-zebra: Avaliação da indução de morte celular programada
(Thesis) Main arguer
 João Sousa (Other)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021 Efeito dos microplásticos no stress oxidativo de minhoca (Eisenia fetida)
(Thesis) Main arguer
 Margarida Alves (Other)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2019 Alterações no sistema antioxidante e na bioenergética celular pela terapia de ozono
(Thesis) Main arguer
 Sofia Isabel Faria Correia (Other)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2018 Avaliação do efeito de um herbicida a base de glifosato no desenvolvimento embrionário do peixe-zebra
(Thesis) Main arguer
 Germano Augusto Bacin Lanzarin (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2018 Biomarcadores de stresse oxidativo em rim e fígado de ratos com lesões pré-neoplásicas na próstata
(Thesis) Main arguer
 Bruno Miguel Soares Martins (Other)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2017 Avaliação de parâmetros de stresse oxidativo no fígado de murganhos K14HPV16 após tratamento com dois fármacos antineoplásicos
(Thesis) Main arguer
 Avaliação de parâmetros de stresse oxidativo no fígado de murganhos K14HPV16 após tratamento com doi (Other)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2017 Efeito de dois Fármacos Antineoplásicos (Cisplatina e Dimetilaminopartenolídeo) a nível dos Parâmetros de Stresse Oxidativo no Fígado de Murganhos com Cancro da Bexiga Induzido com N-Butil-N-(4-Hidroxibutil)-Nitrosamina
(Thesis) Main arguer
 Tânia Alexandra Ferreira Dinis (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2017 Efeito de fenólicos do extrato de casca de tangerina na viabilidade celular e na modulação dos níveis de proteínas reguladoras da apopto
(Thesis) Main arguer
 Elisabete Cristina Silva Pereira (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2017 In vitro evaluation of cytotoxicity and genotoxicity of Porphyra umbilicalis and Gracilaria spp. using Caco-2 cells
(Thesis) Main arguer
 Sara Bizzini (Other)
Universidade de Trás-os-Montes e Alto Douro, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2024 - Current Heliyon Cell Press
2024 - Current Pesticide Biochemistry and Physiology Elsevier
2024 - Current Npj Science of Food Nature
2024 - Current Discover Toxicology
2024 - Current Free Radical Research Taylor & Francis LTD
2024 - Current Pharmacology, Biochemistry and Behavior Elsevier
2024 - Current Lab Animal Nature
2024 - Current Brazilian Journal of Biology
2024 - Current Food Bioscience Elsevier
2024 - Current Naunyn-Schmiedeberg's Archives of Pharmacology Springer
2024 - Current Journal of Fish Biology Wiley
2024 - Current Current Medicinal Chemistry Bentham Science Publ LTD
2024 - Current Journal of Applied Animal Research Taylor & Francis LTD
2024 - Current Journal of Chemotherapy Taylor & Francis LTD
2024 - Current Journal of Agricultural and Food Chemistry American Chemical Society
2024 - Current Journal of Experimental Zoology Part A: Ecological Genetics and Physiology Wiley
2024 - Current IEEE Open Journal of Engineering in Medicine and Biology IEEE
2024 - Current Biochemistry Research International Hindwai LTD
2024 - Current Environmental Research Elsevier
2023 - Current Water Emerging Contaminants & Nanoplastics
2023 - Current Research in Veterinary Science
2023 - Current Process Safety and Environmental Protection
2023 - Current Neurotoxicity Research
2023 - Current Neuroscience Letters
2023 - Current Medical Sciences Forum
2023 - Current Medical Science Monitor
2023 - Current Journal of Polymers and the Environment
2023 - Current Journal of Environmental Sciences
2023 - Current Journal of Environmental Chemical Engineering
2023 - Current Frontiers in Toxicology
2023 - Current Drug and Chemical Toxicology
2023 - Current Current Issues in Molecular Biology
2023 - Current Canadian Journal of Zoology
2023 - Current Marine Pollution Bulletin
2023 - Current Journal of Visualized Experiments
2023 - Current Journal of Pharmacological and Toxicological Methods
2023 - Current Journal of Chemistry
2023 - Current Food and Chemical Toxicology
2023 - Current Cogent Food & Agriculture
2023 - Current Water Biology and Security
2023 - Current Neurochemical Research
2023 - Current Microbiome
2022 - Current Water
2022 - Current Toxicon
2022 - Current Toxicology Reports
2022 - Current Process Biochemistry
2022 - Current Mutation Research/Genetic Toxicology and Environmental Mutagenesis
2022 - Current Brain Research Bulletin
2022 - Current Regional Studies in Marine Science
2022 - Current PeerJ
2022 - Current Journal of Hazardous Materials Advances
2022 - Current Frontiers in Physiology
2022 - Current Frontiers in Environmental Science
2022 - Current Ecotoxicology
2022 - Current Fishes
2022 - Current Environment International
2022 - Current Birth Defects Research
2021 - Current Toxins
2021 - Current Toxicological and Environmental Chemistry
2021 - Current Indian Journal of Pharmaceutical Sciences
2021 - Current Frontiers in Behavioral Neuroscience
2021 - Current Environmental Processes
2021 - Current BMC Anesthesiology
2021 - Current MethodsX
2021 - Current Life
2021 - Current Cardiovascular Toxicology
2021 - Current Frontiers in Pharmacology
2021 - Current Biomolecules
2021 - Current Applied Sciences
2021 - Current Biomedicines
2021 - Current Scientific Reports
2021 - Current Marine Environmental Research
2021 - Current Environmental Science & Ecotechnology
2021 - Current Cells
2021 - Current Biology
2021 - Current Ecotoxicology and Environmental Safety
2021 - Current Antioxidants
2021 - Current Environmental Science and Pollution Research
2021 - Current Environmental Toxicology and Pharmacology
2021 - Current Aquatic Toxicology Elsevier
2020 - Current Metabolism
2020 - Current Aquaculture Research
2020 - Current Aquaculture Reports
2020 - Current Toxicological Sciences
2020 - Current Biological Trace Element Research
2020 - Current Sustainability
2020 - Current Brain Research
2020 - Current Environmental Sciences Europe
2020 - Current Molecules
2020 - Current Aquaculture
2020 - Current Animals
2019 - Current Journal of Food Biochemistry
2019 - Current Brazilian Journal of Pharmaceutical Sciences
2019 - Current Brazilian Archives of Biology and Technology
2019 - Current European Journal of Pharmacology
2019 - Current Pharmaceuticals
2019 - Current Nanomaterials
2019 - Current International Journal of Molecular Sciences
2019 - Current Toxics
2018 - Current Fish & Shellfish Immunology
2018 - Current CyTA - Journal of Food
2018 - Current RSC Advances
2018 - Current Neuroscience and Biobehavioral Reviews
2018 - Current Neurotoxicology and Teratology
2018 - Current Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
2018 - Current Chemosphere
2018 - Current Science of the Total Environment
2017 - Current Psychopharmacology
2017 - Current Acta Histochemica
2017 - Current Plos One
2017 - Current Toxicology and Applied Pharmacology
2017 - Current Toxicology Letters
2017 - Current Environmental Pollution
2016 - Current Journal of Hazardous Materials
2014 - Current Phytotherapy Research

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2022 - 2022 External reviewer of proposals submitted to the 2023 Regular Fondecyt National Projects Competition
Evaluator
 Agencia Nacional de Investigación y Desarrollo, Chile

Interview (tv / radio show)

Program Topic
2024/03/27 - Current 90 Segundos de Ciência Compostos para reduzir o stress de animais em aquacultura

Journal scientific committee

Journal title (ISSN) Publisher
2024/06/01 - Current Special Issue Guest Editor "Effects of Acute Exposure to Toxicants on Oxidative Stress in Aquatic Organisms" - Toxics MDPI
2023 - Current Methods Collection Guest Editor "Experimental Anesthetic Models in Fish: Enhancing Health and Welfare" - Journal of Visualized Experiments
2023 - Current Research Topic Guest Editor "Efficacy and effects of aquatic animal anaesthesia" - Frontiers in Veterinary Science Frontiers
2021 - Current Editorial Board of Aquatic Toxicology
2023 - 2024 Special Issue Guest Editor "Ecotoxicological Effects of Emerging Contaminants on Aquatic Species" - Toxics MDPI
2022 - 2023 Special Issue Guest Editor "Zebrafish Neural Development in Toxicological Studies" - Veterinary Sciences MDPI
2021 - 2022 Special Issue Guest Editor "Ecotoxicology and Environmental Health of Pharmaceuticals and Personal Care Products" - Environmental Research and Public Health MDPI

Mentoring / Tutoring

Topic Student name
2024/02/29 - 2024/05/06 Learning methods on mitochondrial respiration Soumitra Chowdhury

Other jury / evaluation

Activity description Institution / Organization
2024/07/26 - 2024/08/08 Member of the jury for the Research Fellowship BI/Proj2023/i3S/26070808/2024 under the scope of ACLAM2024 approved project
2024/06/24 - 2024/06/24 Member of the jury for the Research Fellowship BI/UTAD/37/2024 under the scope of CITAB activities (UIDB/04033/2020)
2024/06/14 - 2024/06/14 Member of the jury for the Research Fellowship BI/UTAD/31/2024 under the scope of CITAB activities (UIDB/04033/2020)
2023 - 2024 Member of the jury for the Research Fellowship BI/UTAD/66/2023 under the scope of CITAB activities (UIDB/04033/2020) Universidade de Trás-os-Montes e Alto Douro, Portugal
2023 - 2023 Member of the jury for the Research Fellowship BI/UTAD/7/2023 under the scope of the project ENANTIOTOX - Enantioselective ecotoxicity and bioaccumulation of psychoactive substances - PTDC/CTA-AMB/6686/2020 Universidade de Trás-os-Montes e Alto Douro, Portugal
2022 - 2022 Member of the jury for the Research Fellowship BI/UTAD/50/2022 under the scope of CITAB activities (UIDB/04033/2020) Universidade de Trás-os-Montes e Alto Douro, Portugal
Distinctions

Award

2018 ADVID award, Associação de Desenvolvimento da Viticultura Duriense

Other distinction

2018 Food and Function 9 front cover