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João Conde is a Group Leader and Professor at NOVA Medical School, ToxOmics, Nova Medical Research, Universidade NOVA de Lisboa. In 2014, he received his PhD in Biology with a specialization in NanoBiotechnology from the Universidade NOVA de Lisboa and the Universidad de Zaragoza as part of the FP7 European Consortium NanoScieE+-NanoTruck for the development of multifunctional gold nanoparticles for gene silencing. Following that, he was a Marie Curie Fellow at the Massachusetts Institute of Technology, the Harvard-MIT Division for Health Sciences and Technology, and Queen Mary University of London's School of Engineering and Materials Science. From 2017 to 2019, he was a Junior Investigator at the Instituto de Medicina Molecular. In 2019, he won an ERC Starting Grant from the European Research Council (1.5M€) to build a genetic biobarcode to profile breast cancer heterogeneity. He is also a co-founder of the biotech company TargTex, Targeted Therapeutics for Glioblastoma Multiforme (Funding ~20M€, European Innovation Council Accelerator - 14M€). Since 2020, he is also part of the Global Burden of Disease (GBD) Consortium from the Institute for Health Metrics and Evaluation (IHME), University of Washington. In 2023, he partnered with Vector Bioscience Cambridge and AstraZeneca to develop RNA-based cancer therapies from the European Innovation Council Transition (2.5M€). In 2023, was elected for the Scientific Advisory Board of FCT: Fundação para a Ciência e a Tecnologia. The main aspects related to the recognition and diffusion of his early contributions are: more than 100 articles in journals of Cancer Therapy, Oncology, Nanotechnology/Materials Science and NanoMedicine (The Lancet, Nature Materials, The Lancet Oncology, Nature Nanotechnology, JAMA Oncology, Nature Communications, The Lancet Gastroenterol Hepatol, Nature Rev Methods Primers, PNAS, Nature Rev Bioengineering, Accounts of Chemical Research, The Lancet Child Adolesc Health, Progress in Materials Science, ACS Nano, Advanced Materials, JACS, Angewandte Chemie, Advanced Functional Materials, Advanced Science, Trends in Cancer, Trends in Biotechnology, Biomaterials, etc), more than 30 articles are as 1st author and more than 60 articles as corresponding author and cited more than 10.000 times (h-index 50). 25 of them have been selected as cover pages for journals such as Nature Materials, Nature Nanotechnology (COVID-19 Special Issue), The Lancet, The Lancet Oncology, ACS Nano, Adv. Functional Materials, Trends in Cancer, JACS, Angewandte Chemie, ACS Central Science, ACS Sensors, Biomaterials Science, ACS Applied Bio Mat, Adv. Healthcare Materials, Analytical & Bioanalytical Chemistry, and BioTechniques. In addition, 8 international patents on nanomaterials-based platforms for cancer therapy and diagnosis were submitted and approved. He was also awarded several international awards, including the 2023 and 2022 World’s Top 2% Scientists list by Stanford University, the Nanomaterials 2020 Young Investigator Award, the 2021 Biomaterials Science Emerging Investigator, the Top 2% Most cited in Nanoscience/ Nanotechnology from PLOS Biology, the Wellcome Image Awards 2017, the Nano-Micro Letters Researcher Award, and the National Cancer Institute Image Award.
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Identification

Personal identification

Full name
João Conde

Citation names

  • Conde, João

Author identifiers

Ciência ID
A71C-B10E-255E
ORCID iD
0000-0001-8422-6792
Google Scholar ID
https://scholar.google.com/citations?user=H2Flb9kAAAAJ&hl=en
Researcher Id
F-2231-2011
Scopus Author Id
56992468300

Email addresses

  • joao.conde@nms.unl.pt (Professional)

Websites

Knowledge fields

  • Engineering and Technology - Nano-technology
  • Medical and Health Sciences - Medical Biotechnology - Biomaterials
  • Medical and Health Sciences - Clinical Medicine - Oncology
  • Medical and Health Sciences - Basic Medicine - Human Genetics
  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
  • Engineering and Technology - Materials Engineering - Materials Engineering

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Upper intermediate (B2)
Portuguese (Mother tongue)
Education
Degree Classification
2010/01/01 - 2014/01/01
Concluded
 Biology - Nanobiotechnology (Doutoramento)
Universidade Nova de Lisboa, Portugal

Universidad de Zaragoza, Spain
2009
Concluded
 Biologia (Doutoramento)
Major in Especialidade: Biotecnologia
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Cancer Theragnostics-Multifunctional gold nanoparticles for diagnostics and therapy" (THESIS/DISSERTATION)
Affiliation

Science

Category
Host institution 		Employer
2020/02 - Current Principal Investigator (Research) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2017/09/01 - 2020/01/31 Auxiliary Researcher (Research) Instituto de Medicina Molecular, Portugal
Instituto de Medicina Molecular, Portugal
2016/05/01 - 2017/05/01 Postdoc (Research) Queen Mary University of London, United Kingdom
Queen Mary University of London School of Engineering and Materials Science, United Kingdom
2014/03/01 - 2017/05/01 Postdoc (Research) Massachusetts Institute of Technology, United States
Massachusetts Institute of Technology, United States
(...)
2009 - 2010 Researcher (Research) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2007 - 2009 Research Trainee (Research) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2020/02/01 - Current Assistant Professor (University Teacher) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Others

Category
Host institution 		Employer
2010/01/01 - 2014/01/01 PhD Student Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Projects

Grant

Designation Funders
2023 - 2026 RNA-based cancer therapies
European Innovation Council – EIC Transition Grant
Co-Principal Investigator (Co-PI)
Ongoing
2021/01/01 - 2024/01/01 Biomimetic cell membrane-coated vitamin E-based micelles for multimodal pancreatic cancer nanotheranostics
PTDC/BTM-MAT/4738/2020
PTDC/BTM-MAT/4738/2020
Principal investigator
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade de Coimbra, Portugal

Universidade Nova de Lisboa, Portugal

University of Strathclyde, United Kingdom

Universidade de Santiago de Compostela, Spain
N/A

Fundação para a Ciência e a Tecnologia
Ongoing
2014/05 - 2017/04 Marie Curie Grant - CancerHydrogelPatch
FP7-PEOPLE-2013-IOF
Post-doc Fellow
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
2016 - 2017 SuprHApolymers - Engineering self-assembly of hyaluronan-based glycopolymers with peptides
631871
Researcher
2012 - 2015 Silence is golden (siAu) - silencing the silencers via multifunctional gold nanoconjugates towards cancer therapy
PTDC/BBB-NAN/1812/2012
Research Fellow
Fundação para a Ciência e a Tecnologia, Portugal
Concluded
2010/01 - 2014/01 FCT PhD Grant - Cancer Theranostics: Multifunctional gold nanoparticles for diagnostics and therapy
SFRH/BD/62957/2009
 Fundação para a Ciência e a Tecnologia
2012 - 2014 NANOTRUCK- Multifunctional gold nanoparticles for gene therapy.
ERANET-NANOSCIERA NANOTRUC
ERANET-NANOSCIERA NANOTRUC
PhD Student Fellow
N/A
Concluded
2010 - 2013 Nanosystems for delivery of caged compounds
PTDC/QUI-QUI/ 112597/2009
Research Fellow
Fundação para a Ciência e a Tecnologia, Portugal
Concluded
2009 - 2012 Sensitive and selective detection of DNA/RNA based on functionalized gold nanoparticles - application to pathogen detection; mutation detection and RNA quantification
PTDC/BIO/66514/2006
Research Fellow
Fundação para a Ciência e a Tecnologia, Portugal
Concluded

Contract

Designation Funders
2020/02/01 - 2025/01/31 Cancer heterogeneity and therapy profiling using bioresponsive nanohydrogels for the delivery of multicolor logic genetic circuits.
848325
Principal investigator
Universidade Nova de Lisboa, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
European Commission

European Research Council
Ongoing
2022/01/01 - 2024/12/31 combined immUNotherapeutIC approach for targeting bone marrow microenvironment in Multiple Myeloma
PTDC/MED-ONC/1215/2021
Fundação Champalimaud, Portugal

Universidade Nova de Lisboa, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/01/01 - 2024/06/30 Patient-derived lung cancer organoids for recreating tumor spread through AIR spaces phenomenon
2022.07775.PTDC
Universidade Nova de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/03/01 - 2020/01/31 Hydrogel scaffolds for delivery of gene therapies
CEECIND/01688/2017/CP1396/CT0006
Researcher
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 Instituto de Medicina Molecular
UID/BIM/50005/2019
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011/03/01 - 2014/08/31 NANOLIGHT - Nanosystems for delivery of caged compounds
PTDC/QUI-QUI/112597/2009
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2013/12/31 Strategic Project - UI 9 - 2011-2012
PEst-OE/SAU/UI0009/2011
Universidade NOVA de Lisboa NOVA Medical School, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2009/07/01 - 2012/06/30 Nanotruck - Multifunctional Gold Nanoparticles for Gene Therapy
NanoSciERA/0001/2008
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade Nova de Lisboa Centro de Toxicogenómica e Saúde Humana, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2018 - 2019 Recombinant albumin conjugates for cancer therapy
Albumedix
Researcher
Albumedix, United Kingdom
Concluded
Outputs

Publications

Book chapter
  1. Shuturminska, Kseniya; O'Malley, Clare; Collis, Dominic W.P.; Conde, João; Azevedo, Helena S.. "Displaying biofunctionality on materials through templated self-assembly". In Self-assembling Biomaterials, 341-370. Elsevier, 2018.
    Published • 10.1016/b978-0-08-102015-9.00018-6
  2. Conde, João; Tian, Furong; Baptista, Pedro V.; de la Fuente, Jesús M.. "Multifunctional Gold Nanocarriers for Cancer Theranostics: From Bench to Bedside and Back Again?". In Advances in Delivery Science and Technology, 295-328. Springer International Publishing, 2014.
    Published • 10.1007/978-3-319-08084-0_11
  3. Baptista, P. V.; Doria, G.; Conde, J.. "Alloy metal nanoparticles for multicolor cancer diagnostics". edited by Parak, W. J.; Yamamoto, K.; Osinski, M.. 2011.
    10.1117/12.879025
Book review
  1. Conde, João; Doria, Gonçalo; Baptista, Pedro Viana. "Noble metal nanoparticles applications in cancer". http://hdl.handle.net/10362/106985.
    https://doi.org/10.1155/2012/751075
  2. Lopes, Daniela; Lopes, Joana; Pereira-Silva, Miguel; Peixoto, Diana; Rabiee, Navid; Veiga, Francisco; Moradi, Omid; et al. "Bioengineered exosomal-membrane-camouflaged abiotic nanocarriers". http://hdl.handle.net/10362/152470.
    https://doi.org/10.1186/s40779-023-00453-z
  3. Lopes, Joana; Lopes, Daniela; Pereira-Silva, Miguel; Peixoto, Diana; Veiga, Francisco; Hamblin, Michael R.; Conde, João; et al. "Macrophage Cell Membrane-Cloaked Nanoplatforms for Biomedical Applications". http://hdl.handle.net/10362/141369.
    https://doi.org/10.1002/smtd.202200289
  4. Talebian, Sepehr; Mendes, Bárbara; Conniot, João; Farajikhah, Syamak; Dehghani, Fariba; Li, Zhongyan; Bitoque, Diogo; et al. "Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants". http://hdl.handle.net/10362/149674.
    https://doi.org/10.1002/advs.202207603
  5. Rahimi, Hossein; Salehiabar, Marziyeh; Barsbay, Murat; Ghaffarlou, Mohammadreza; Kavetskyy, Taras; Sharafi, Ali; Davaran, Soodabeh; et al. "CRISPR Systems for COVID-19 Diagnosis". http://hdl.handle.net/10362/147350.
    https://doi.org/10.1021/acssensors.0c02312
  6. Conniot, João; Talebian, Sepehr; Simões, Susana; Ferreira, Lino; Conde, João. "Revisiting gene delivery to the brain". http://hdl.handle.net/10362/147349.
    https://doi.org/10.1039/d0bm01278e
  7. Chavda, Vivek P; Balar, Pankti C; Nalla, Lakshmi Vineela; Bezbaruah, Rajashri; Gogoi, Niva Rani; Gajula, Siva Nageswara Rao; Peng, Berney; et al. "Conjugated Nanoparticles for Solid Tumor Theranostics". http://hdl.handle.net/10362/159718.
    https://doi.org/10.1021/acsomega.3c05069
  8. Zhong, Ruibo; Talebian, Sepehr; Mendes, Bárbara B.; Wallace, Gordon; Langer, Robert; Conde, João; Shi, Jinjun. "Hydrogels for RNA delivery". http://hdl.handle.net/10362/154204.
    https://doi.org/10.1038/s41563-023-01472-w
  9. Kommineni, Nagavendra; Chaudhari, Ruchita; Conde, João; Tamburaci, Sedef; Cecen, Berivan; Chandra, Pranjal; Prasad, Rajendra. "Engineered Liposomes in Interventional Theranostics of Solid Tumors". http://hdl.handle.net/10362/157009.
    https://doi.org/10.1021/acsbiomaterials.3c00510
  10. Di Filippo, Leonardo Delello; de Carvalho, Suzana Gonçalves; Duarte, Jonatas Lobato; Luiz, Marcela Tavares; Paes Dutra, Jessyca Aparecida; de Paula, Geanne Aparecida; Chorilli, Marlus; Conde, João. "A receptor-mediated landscape of druggable and targeted nanomaterials for gliomas". http://hdl.handle.net/10362/153784.
    https://doi.org/10.1016/j.mtbio.2023.100671
  11. Conde, João; Dias, Jorge T.; Grazu, Valeria; Moros, Maria; Baptista, Pedro; de la Fuente, Jesus M.; Conde, Joao; et al. "Revisiting 30 years of biofunctionalization and surface chemistry of inorganic nanoparticles for nanomedicine". 2, (2014): http://hdl.handle.net/10362/106889.
    https://doi.org/10.3389/fchem.2014.00048
Conference poster
  1. yasmina orraca; Bárbara B. Mendes; Amaral-Silva, Daniela; Conniot, João; Conde, João; helena soares. "Natural-based photocrosslinkable hydrogels for rheumatoid arthritis treatment". Paper presented in NMS PhD retreat, 2022.
Edited book
  1. Conde, João. Handbook of Nanomaterials for Cancer Theranostics. Elsevier. 2018.
    Published • 10.1016/c2016-0-04699-5
Journal article
  1. Chen X; Mendes BB; Zhuang Y; Conniot J; Mercado Argandona S; Melle F; Sousa DP; et al. "A Fluorinated BODIPY-Based Zirconium Metal-Organic Framework for In Vivo Enhanced Photodynamic Therapy.". Journal of the American Chemical Society (2024): http://europepmc.org/abstract/med/38174960.
    10.1021/jacs.3c12416
  2. Prasad R; Peng B; Mendes BB; Kilian HI; Gorain M; Zhang H; Kundu GC; et al. "Biomimetic bright optotheranostics for metastasis monitoring and multimodal image-guided breast cancer therapeutics.". Journal of controlled release : official journal of the Controlled Release Society (2024): http://europepmc.org/abstract/med/38281670.
    10.1016/j.jconrel.2024.01.056
  3. Mensah GA; Fuster V; Murray CJL; Roth GA; Global Burden of Cardiovascular Diseases and Risks Collaborators. "Global Burden of Cardiovascular Diseases and Risks, 1990-2022.". Journal of the American College of Cardiology (2023): http://europepmc.org/abstract/med/38092509.
    10.1016/j.jacc.2023.11.007
  4. Fu L; Zhang Y; Farokhzad RA; Mendes BB; Conde J; Shi J. "'Passive' nanoparticles for organ-selective systemic delivery: design, mechanism and perspective.". Chemical Society reviews (2023): http://europepmc.org/abstract/med/37817741.
    10.1039/d2cs00998f
  5. Chavda VP; Balar PC; Nalla LV; Bezbaruah R; Gogoi NR; Gajula SNR; Peng B; et al. "Conjugated Nanoparticles for Solid Tumor Theranostics: Unraveling the Interplay of Known and Unknown Factors.". ACS omega (2023): http://europepmc.org/abstract/med/37867666.
    10.1021/acsomega.3c05069
  6. Kommineni N; Chaudhari R; Conde J; Tamburaci S; Cecen B; Chandra P; Prasad R. "Engineered Liposomes in Interventional Theranostics of Solid Tumors.". ACS biomaterials science & engineering (2023): http://europepmc.org/abstract/med/37450683.
    10.1021/acsbiomaterials.3c00510
  7. Talebian S; Dehghani F; Weiss PS; Conde J. "Evolution of CRISPR-enabled biosensors for amplification-free nucleic acid detection.". Trends in biotechnology (2023): http://europepmc.org/abstract/med/37516612.
    10.1016/j.tibtech.2023.07.004
  8. Di Filippo LD; de Carvalho SG; Duarte JL; Luiz MT; Paes Dutra JA; de Paula GA; Chorilli M; Conde J. "A receptor-mediated landscape of druggable and targeted nanomaterials for gliomas.". Materials today. Bio (2023): http://europepmc.org/abstract/med/37273792.
    10.1016/j.mtbio.2023.100671
  9. Bárbara B. Mendes; Oliveira, Jhenifer; Conde, João. Corresponding author: Bárbara B. Mendes. "Biomimetic hydrogel supporting baths as an alternative to initiate and maintain breast tumor-derived organoids culture". MedComm - Biomaterials and Applications (2023):
    Accepted
  10. Lopes D; Lopes J; Pereira-Silva M; Peixoto D; Rabiee N; Veiga F; Moradi O; et al. "Bioengineered exosomal-membrane-camouflaged abiotic nanocarriers: neurodegenerative diseases, tissue engineering and regenerative medicine.". Military Medical Research (2023): http://europepmc.org/abstract/med/37101293.
    10.1186/s40779-023-00453-z
  11. Zhong R; Talebian S; Mendes BB; Wallace G; Langer R; Conde J; Shi J. "Hydrogels for RNA delivery.". Nature materials (2023): http://europepmc.org/abstract/med/36941391.
    10.1038/s41563-023-01472-w
  12. Conde J; Langer R; Rueff J; Conde, João; Langer, Robert; Rueff, José. "mRNA therapy at the convergence of genetics and nanomedicine.". Nature nanotechnology (2023): http://europepmc.org/abstract/med/36932293.
    10.1038/s41565-023-01347-w
  13. Talebian S; Mendes B; Conniot J; Farajikhah S; Dehghani F; Li Z; Bitoque D; et al. "Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants.". Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023): http://europepmc.org/abstract/med/36782094.
    10.1002/advs.202207603
  14. Shao, Minmin; Lopes, Daniela; Lopes, Joana; Yousefiasl, Satar; Macário-Soares, Ana; Peixoto, Diana; Ferreira-Faria, Inês; et al. "Exosome membrane-coated nanosystems: Exploring biomedical applications in cancer diagnosis and therapy". Matter 6 3 (2023): 761-799. http://dx.doi.org/10.1016/j.matt.2023.01.012.
    10.1016/j.matt.2023.01.012
  15. Ravasco, João m. j. m.; Paiva-Santos, Ana cláudia; Conde, João. "Technological challenges of biomembrane-coated top-down cancer nanotherapy". (2023): http://hdl.handle.net/10362/152744.
    https://doi.org/10.1038/s44222-022-00008-2
  16. Khazaei Monfared, Yousef; Mahmoudian, Mohammad; Zakeri-Milani, Parvin; Cecone, Claudio; Hayashi, Tomoya; Ishii, Ken J; Conde, João; et al. "Intratumoural Delivery of mRNA Loaded on a Cationic Hyper-Branched Cyclodextrin-Based Polymer Induced an Anti-Tumour Immunological Response in Melanoma". Cancers (2023): http://hdl.handle.net/10362/157747.
    https://doi.org/10.3390/cancers15143748
  17. Prasad, Rajendra; Mendes, Bárbara B.; Gorain, Mahadeo; Chandra Kundu, Gopal; Gupta, Narendra; Peng, Berney; Aung Win, Eaint Honey; Qing, He; Conde, João. "Bioinspired and biomimetic cancer-cell-derived membrane nanovesicles for preclinical tumor-targeted nanotheranostics". (2023): http://hdl.handle.net/10362/160669.
    https://doi.org/10.1016/j.xcrp.2023.101648
  18. Sousa DP; Conde J; Sousa, Diana P.; Conde, João. "Using gold nanobeacons as a theranostic technique to recognize, detect, and inhibit specific nucleic acids.". STAR protocols (2022): http://europepmc.org/abstract/med/36595910.
    10.1016/j.xpro.2022.101916
  19. Sousa DP; Conde J; Sousa, Diana P.; Conde, João. "Gold Nanoconjugates for miRNA Modulation in Cancer Therapy: From miRNA Silencing to miRNA Mimics.". ACS materials Au (2022): http://europepmc.org/abstract/med/36397876.
    10.1021/acsmaterialsau.2c00042
  20. Zhang Z; Conniot J; Amorim J; Jin Y; Prasad R; Yan X; Fan K; Conde J. "Nucleic acid-based therapy for brain cancer: Challenges and strategies.". Journal of controlled release : official journal of the Controlled Release Society (2022): http://europepmc.org/abstract/med/35970297.
    10.1016/j.jconrel.2022.08.014
  21. GBD 2019 Cancer Risk Factors Collaborators. "The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019.". Lancet (London, England) (2022): http://europepmc.org/abstract/med/35988567.
    10.1016/s0140-6736(22)01438-6
  22. Nosrati H; Ghaffarlou M; Salehiabar M; Mousazadeh N; Abhari F; Barsbay M; Ertas YN; et al. "Magnetite and bismuth sulfide Janus heterostructures as radiosensitizers for in vivo enhanced radiotherapy in breast cancer.". Biomaterials advances (2022): http://europepmc.org/abstract/med/36027669.
    10.1016/j.bioadv.2022.213090
  23. Lopes J; Lopes D; Pereira-Silva M; Peixoto D; Veiga F; Hamblin MR; Conde J; et al. "Macrophage Cell Membrane-Cloaked Nanoplatforms for Biomedical Applications.". Small methods (2022): http://europepmc.org/abstract/med/35768282.
    10.1002/smtd.202200289
  24. Mendes, Bárbara B.; Conniot, João; Avital, Aviram; Yao, Dongbao; Jiang, Xingya; Zhou, Xiang; Sharf-pauker, Noga; et al. "Nanodelivery of nucleic acids.". Nature reviews. Methods primers (2022): http://europepmc.org/abstract/med/35480987.
    10.1038/s43586-022-00104-y
  25. "Global, regional, and national burden of colorectal cancer and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.". The lancet. Gastroenterology & hepatology (2022): http://europepmc.org/abstract/med/35397795.
    10.1016/s2468-1253(22)00044-9
  26. "Burden of non-communicable diseases among adolescents aged 10-24 years in the EU, 1990-2019: a systematic analysis of the Global Burden of Diseases Study 2019.". The Lancet. Child & adolescent health (2022): http://europepmc.org/abstract/med/35339209.
    10.1016/s2352-4642(22)00073-6
  27. "Bioinspired soft nanovesicles for site-selective cancer imaging and targeted therapies.". Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology (2022): http://europepmc.org/abstract/med/35318815.
    10.1002/wnan.1792
  28. Kocarnik, Jonathan M.; Compton, Kelly; Dean, Frances E.; Fu, Weijia; Gaw, Brian L.; Harvey, James D.; Henrikson, Hannah Jacqueline; et al. "Cancer Incidence, Mortality, Years of Life Lost, Years Lived with Disability, and Disability-Adjusted Life Years for 29 Cancer Groups from 2010 to 2019". (2022): http://hdl.handle.net/10362/135995.
    https://doi.org/10.1001/jamaoncol.2021.6987
  29. Sharma, Rajesh; Abbasi-kangevari, Mohsen; Abd-rabu, Rami; Abidi, Hassan; Abu-gharbieh, Eman; Acuna, Juan Manuel; Adhikari, Sangeet; et al. "Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019". (2022): http://hdl.handle.net/10362/136124.
    https://doi.org/10.1016/S2468-1253(22)00044-9
  30. Alvarez, Elysia M; Force, Lisa M; Xu, Rixing; Compton, Kelly; Lu, Dan; Henrikson, Hannah Jacqueline; Kocarnik, Jonathan M; et al. "The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019". (2022): http://hdl.handle.net/10362/129679.
    https://doi.org/10.1016/S1470-2045(21)00581-7
  31. Zhang, Zixia; Conniot, João; Amorim, Joana; Jin, Yiliang; Prasad, Rajendra; Yan, Xiyun; Fan, Kelong; Conde, João. "Nucleic acid-based therapy for brain tumor". (2022): http://hdl.handle.net/10362/143307.
    https://doi.org/10.1016/j.jconrel.2022.08.014
  32. Armocida, Benedetta; Monasta, Lorenzo; Sawyer, Susan; Bustreo, Flavia; Segafredo, Giulia; Castelpietra, Giulio; Ronfani, Luca; et al. "Burden of non-communicable diseases among adolescents aged 10-24 years in the EU, 1990-2019". (2022): http://hdl.handle.net/10362/136118.
    https://doi.org/10.1016/S2352-4642(22)00073-6
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  59. Conde, João. "Gastric Parietal Cell and Intestinal Goblet Cell Secretion: a Novel Cell-Mediated In Vivo Metal Nanoparticle Metabolic Pathway Enhanced with Diarrhea Via Chinese Herbs". Nanoscale Research Letters (2019): http://dx.doi.org/10.1186/s11671-019-2908-z.
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  60. Conde, João. "Oral pH sensitive GNS@ab nanoprobes for targeted therapy of Helicobacter pylori without disturbance gut microbiome". Nanomedicine: Nanotechnology, Biology and Medicine (2019): http://dx.doi.org/10.1016/j.nano.2019.102019.
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  62. Fan, Kelong; Jia, Xiaohua; Zhou, Meng; Wang, Kun; Conde, Joao; He, Jiuyang; Tian, Jie; Yan, Xiyun. "Ferritin Nanocarrier Traverses the Blood Brain Barrier and Kills Glioma.". ACS nano (2018): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:29608290&KeyUID=MEDLINE:29608290.
    10.1021/acsnano.7b06969
  63. McCully, Mark; Conde, Joao; V Baptista, Pedro; Mullin, Margaret; Dalby, Matthew J; Berry, Catherine C; McCully, Mark; et al. "Nanoparticle-antagomiR based targeting of miR-31 to induce osterix and osteocalcin expression in mesenchymal stem cells.". PloS one 13 2 (2018): e0192562-e0192562. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:29444183&KeyUID=MEDLINE:29444183.
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  64. Talebian, Sepehr; Foroughi, Javad; Wade, Samantha J; Vine, Kara L; Dolatshahi-Pirouz, Alireza; Mehrali, Mehdi; Conde, Joao; Wallace, Gordon G. "Biopolymers for Antitumor Implantable Drug Delivery Systems: Recent Advances and Future Outlook.". Advanced materials (Deerfield Beach, Fla.) (2018): e1706665-e1706665. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:29756237&KeyUID=MEDLINE:29756237.
    10.1002/adma.201706665
  65. Sojinrin, Tobiloba; Conde, Joao; Liu, Kangze; Curtin, James; Byrne, Hugh J.; Cui, Daxiang; Tian, Furong. "Plasmonic gold nanoparticles for detection of fungi and human cutaneous fungal infections". Analytical and Bioanalytical Chemistry 409 19 (2017): 4647-4658. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000404906800015&KeyUID=WOS:000404906800015.
    10.1007/s00216-017-0414-7
  66. Goodarzi, Saba; Da Ros, Tatiana; Conde, Joao; Sefat, Farshid; Mozafari, Masoud. "Fullerene: biomedical engineers get to revisit an old friend". Materials Today 20 8 (2017): 460-480. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000414598800016&KeyUID=WOS:000414598800016.
    10.1016/j.mattod.2017.03.017
  67. Liu, Tzu-Ming; Conde, Joao; Lipinski, Tomasz; Bednarkiewicz, Artur; Huang, Chih-Chia. "Smart NIR linear and nonlinear optical nanomaterials for cancer theranostics: Prospects in photomedicine". Progress in Materials Science 88 (2017): 89-135. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000402528500003&KeyUID=WOS:000402528500003.
    10.1016/j.pmatsci.2017.03.004
  68. Song, Hyun Seok; Kwon, Oh Seok; Kim, Jae-Hong; Conde, Joao; Artzi, Natalie. "3D hydrogel scaffold doped with 2D graphene materials for biosensors and bioelectronics". Biosensors & Bioelectronics 89 (2017): 187-200. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000391077000014&KeyUID=WOS:000391077000014.
    10.1016/j.bios.2016.03.045
  69. Shi, Yejiao; Conde, Joao; Azevedo, Helena S; Conde, João; Azevedo, Helena S.. "Empowering the Potential of Cell-Penetrating Peptides for Targeted Intracellular Delivery via Molecular Self-Assembly.". Advances in experimental medicine and biology 1030 (2017): 265-278. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:29081058&KeyUID=MEDLINE:29081058.
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    10.1021/acs.accounts.6b00536
  71. Conde, Joao; Shomron, Noam; Artzi, Natalie. "Biomaterials for Abrogating Metastasis: Bridging the Gap between Basic and Translational Research". Advanced Healthcare Materials 5 18 (2016): 2312-2319. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000384554300001&KeyUID=WOS:000384554300001.
    10.1002/adhm.201600414
  72. Tian, Furong; Conde, Joao; Bao, Chenchen; Chen, Yunsheng; Curtin, James; Cui, Daxiang. "Gold nanostars for efficient in vitro and in vivo real-time SERS detection and drug delivery via plasmonic-tunable Raman/FTIR imaging". Biomaterials 106 (2016): 87-97. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000383934300008&KeyUID=WOS:000383934300008.
    10.1016/j.biomaterials.2016.08.014
  73. Bao, Chenchen; Conde, Joao; Pan, Fei; Li, Chao; Zhang, Chunlei; Tian, Furong; Liang, Shujing; de la Fuente, Jesus M.; Cui, Daxiang. "Gold nanoprisms as a hybrid in vivo cancer theranostic platform for in situ photoacoustic imaging, angiography, and localized hyperthermia". Nano Research 9 4 (2016): 1043-1056. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000375081400016&KeyUID=WOS:000375081400016.
    10.1007/s12274-016-0996-y
  74. Gilam, Avital; Conde, Joao; Weissglas-Volkov, Daphna; Oliva, Nuria; Friedman, Eitan; Artzi, Natalie; Shomron, Noam. "Local microRNA delivery targets Palladin and prevents metastatic breast cancer". Nature Communications 7 (2016): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000385384100002&KeyUID=WOS:000385384100002.
    10.1038/ncomms12868
  75. Kwon, Oh Seok; Song, Hyun Seok; Conde, Joao; Kim, Hyoung-il; Artzi, Natalie; Kim, Jae-Hong. "Dual-Color Emissive Upconversion Nanocapsules for Differential Cancer Bioimaging In Vivo". Acs Nano 10 1 (2016): 1512-1521. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000369115800169&KeyUID=WOS:000369115800169.
    10.1021/acsnano.5b07075
  76. Ma, Yue; Fu, Hualin; Zhang, Chunlei; Cheng, Shangli; Gao, Jie; Wang, Zhen; Jin, Weilin; Conde, Joao; Cui, Daxiang. "Chiral Antioxidant-based Gold Nanoclusters Reprogram DNA Epigenetic Patterns". Scientific Reports 6 (2016): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000383645500001&KeyUID=WOS:000383645500001.
    10.1038/srep33436
  77. Zhang Yi; Conde Joao; Oliva Nuria; Artzi Natalie. "Dual-sensitive hydrogel composite for local release and selective uptake of chemotherapy for the treatment of breast cancer". Front. Bioeng. Biotechnol. 4 (2016):
    10.3389/conf.fbioe.2016.01.01331
  78. Conde, Joao; Oliva, Nuria; Atilano, Mariana; Song, Hyun Seok; Artzi, Natalie. "Self-assembled RNA-triple-helix hydrogel scaffold for microRNA modulation in the tumour microenvironment". Nature Materials 15 3 (2016): 353-+. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000370967400022&KeyUID=WOS:000370967400022.
    10.1038/NMAT4497
  79. Conde, Joao; Oliva, Nuria; Artzi, Natalie. "Revisiting the 'One Material Fits All' Rule for Cancer Nanotherapy". Trends in Biotechnology 34 8 (2016): 618-626. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000380601100005&KeyUID=WOS:000380601100005.
    10.1016/j.tibtech.2016.05.004
  80. Conde, Joao; Oliva, Nuria; Zhang, Yi; Artzi, Natalie. "Local triple-combination therapy results in tumour regression and prevents recurrence in a colon cancermodel.". Nature materials 15 10 (2016): 1128-38. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:27454043&KeyUID=MEDLINE:27454043.
    10.1038/nmat4707
  81. Conde, Joao; Arnold, Christina E.; Tian, Furong; Artzi, Natalie. "RNAi nanomaterials targeting immune cells as an anti-tumor therapy: the missing link in cancer treatment?". Materials Today 19 1 (2016): 29-43. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000368910800018&KeyUID=WOS:000368910800018.
    10.1016/j.mattod.2015.07.005
  82. Liu, Tzu-Ming; Conde, Joao; Lipinski, Tomasz; Bednarkiewicz, Artur; Huang, Chih-Chia. "Revisiting the classification of NIR-absorbing/emitting nanomaterials for in vivo bioapplications". Npg Asia Materials 8 (2016): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000383415100001&KeyUID=WOS:000383415100001.
    10.1038/am.2016.106
  83. Conde, Joao; Artzi, Natalie. "The next generation of smart gold nanobeacons: nanotheranostics is ready for prime time.". Nanomedicine (London, England) 10 10 (2015): 1535-8. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:26008191&KeyUID=MEDLINE:26008191.
    10.2217/nnm.15.42
  84. McCully, Mark; Hernandez, Yulan; Conde, Joao; Baptista, Pedro V.; de la Fuente, Jesus M.; Hursthouse, Andrew; Stirling, David; Berry, Catherine C.. "Significance of the balance between intracellular glutathione and polyethylene glycol for successful release of small interfering RNA from gold nanoparticles". Nano Research 8 10 (2015): 3281-3292. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000362588100016&KeyUID=WOS:000362588100016.
    10.1007/s12274-015-0828-5
  85. Conde, Joao; Tian, Furong; Hernandez, Yulan; Bao, Chenchen; Baptista, Pedro V.; Cui, Daxiang; Stoeger, Tobias; de la Fuente, Jesus M.. "RNAi-based glyconanoparticles trigger apoptotic pathways for in vitro and in vivo enhanced cancer-cell killing". Nanoscale 7 19 (2015): 9083-9091. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000354204400049&KeyUID=WOS:000354204400049.
    10.1039/c4nr05742b
  86. Conde, Joao. "The Golden Age in Cancer Nanobiotechnology: Quo Vadis?". Frontiers in bioengineering and biotechnology 3 (2015): 142-142. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:26442256&KeyUID=MEDLINE:26442256.
    10.3389/fbioe.2015.00142
  87. Conde, Joao; Edelman, Elazer R.; Artzi, Natalie. "Target-responsive DNA/RNA nanomaterials for microRNA sensing and inhibition: The jack-of-all-trades in cancer nanotheranostics?". Advanced Drug Delivery Reviews 81 (2015): 169-183. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000348621600014&KeyUID=WOS:000348621600014.
    10.1016/j.addr.2014.09.003
  88. Conde, Joao; Ambrosone, Alfredo; Hernandez, Yulan; Tian, Furong; McCully, Mark; Berry, Catherine C.; Baptista, Pedro V.; Tortiglione, Claudia; de la Fuente, Jesus M.. "15 years on siRNA delivery: Beyond the State-of-the-Art on inorganic nanoparticles for RNAi therapeutics". Nano Today 10 4 (2015): 421-450. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000366766000006&KeyUID=WOS:000366766000006.
    10.1016/j.nantod.2015.06.008
  89. Bao, Chenchen; Conde, Joao; Curtin, James; Artzi, Natalie; Tian, Furong; Cui, Daxiang. "Bioresponsive antisense DNA gold nanobeacons as a hybrid in vivo theranostics platform for the inhibition of cancer cells and metastasis". Scientific Reports 5 (2015): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000358152900001&KeyUID=WOS:000358152900001.
    10.1038/srep12297
  90. Conde, Joao; Artzi, Natalie. "Are RNAi and miRNA therapeutics truly dead?". Trends in Biotechnology 33 3 (2015): 141-144. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000350839200001&KeyUID=WOS:000350839200001.
    10.1016/j.tibtech.2014.12.005
  91. Oliva, Nuria; Unterman, Shimon; Zhang, Yi; Conde, Joao; Song, Hyun Seok; Artzi, Natalie. "Personalized Medicine: Personalizing Biomaterials for Precision Nanomedicine Considering the Local Tissue Microenvironment (Adv. Healthcare Mater. 11/2015).". Advanced healthcare materials 4 11 (2015): 1577-1577. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:26250950&KeyUID=MEDLINE:26250950.
    10.1002/adhm.201570063
  92. Tian, Furong; Clift, Martin J. D.; Casey, Alan; del Pino, Pablo; Pelaz, Beatriz; Conde, Joao; Byrne, Hugh J.; et al. "Investigating the role of shape on the biological impact of gold nanoparticles in vitro". Nanomedicine 10 17 (2015): 2643-2657. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000361474600003&KeyUID=WOS:000361474600003.
    10.2217/nnm.15.103
  93. Restani, Rita B.; Conde, Joao; Pires, Rita F.; Martins, Pedro; Fernandes, Alexandra R.; Baptista, Pedro V.; Bonifacio, Vasco D. B.; Aguiar-Ricardo, Ana. "POxylated Polyurea Dendrimers: Smart Core-Shell Vectors with IC50 Lowering Capacity". Macromolecular Bioscience 15 8 (2015): 1045-1051. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000359629600002&KeyUID=WOS:000359629600002.
    10.1002/mabi.201500131
  94. Oliva, Nuria; Unterman, Shimon; Zhang, Yi; Conde, Joao; Song, Hyun Seok; Artzi, Natalie. "Personalizing Biomaterials for Precision Nanomedicine Considering the Local Tissue Microenvironment". Advanced Healthcare Materials 4 11 (2015): 1584-1599. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000359382600001&KeyUID=WOS:000359382600001.
    10.1002/adhm.201400778
  95. Conde, Joao; Bao, Chenchen; Tan, Yeqi; Cui, Daxiang; Edelman, Elazer R.; Azevedo, Helena S.; Byrne, Hugh J.; Artzi, Natalie; Tian, Furong. "Dual Targeted Immunotherapy via In Vivo Delivery of Biohybrid RNAi-Peptide Nanoparticles to Tumor-Associated Macrophages and Cancer Cells". Advanced Functional Materials 25 27 (2015): 4183-4194. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000357996600001&KeyUID=WOS:000357996600001.
    10.1002/adfm.201501283
  96. Conde, Joao; Oliva, Nuria; Artzi, Natalie. "Implantable hydrogel embedded dark-gold nanoswitch as a theranostic probe to sense and overcome cancer multidrug resistance". Proceedings of the National Academy of Sciences of the United States of America 112 11 (2015): E1278-E1287. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000351060000017&KeyUID=WOS:000351060000017.
    10.1073/pnas.1421229112
  97. Child, Hannah Winifred; Hernandez, Yulan; Conde, Joao; Mullin, Margaret; Baptista, Pedro; Maria de la Fuente, Jesus; Berry, Catherine Cecilia. "Gold nanoparticle-siRNA mediated oncogene knockdown at RNA and protein level, with associated gene effects". Nanomedicine 10 16 (2015): 2513-2525. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000360223100005&KeyUID=WOS:000360223100005.
    10.2217/NNM.15.95
  98. Conde, Joao; Bao, Chenchen; Cui, Daxiang; Baptista, Pedro V.; Tian, Furong. "Antibody-drug gold nanoantennas with Raman spectroscopic fingerprints for in vivo tumour theranostics". Journal of Controlled Release 183 (2014): 87-93. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000335554400010&KeyUID=WOS:000335554400010.
    10.1016/j.jconrel.2014.03.045
  99. Bao, Chenchen; Conde, Joao; Polo, Ester; del Pino, Pablo; Moros, Maria; Baptista, Pedro V.; Grazu, Valeria; Cui, Daxiang; de la Fuente, Jesus M.. "A promising road with challenges: where are gold nanoparticles in translational research?". Nanomedicine 9 15 (2014): 2353-2370. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000346176800010&KeyUID=WOS:000346176800010.
    10.2217/NNM.14.155
  100. Restani, Rita B.; Conde, Joao; Baptista, Pedro V.; Cidade, Maria Teresa; Braganca, Ana M.; Morgado, Jorge; Correia, Ilidio J.; Aguiar-Ricardo, Ana; Bonifacio, Vasco D. B.. "Polyurea dendrimer for efficient cytosolic siRNA delivery". Rsc Advances 4 97 (2014): 54872-54878. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000344600400092&KeyUID=WOS:000344600400092.
    10.1039/c4ra09603g
  101. Conde, Joao; Larguinho, Miguel; Cordeiro, Ana; Raposo, Luis R.; Costa, Pedro M.; Santos, Susana; Diniz, Mario S.; Fernandes, Alexandra R.; Baptista, Pedro V.. "Gold-nanobeacons for gene therapy: evaluation of genotoxicity, cell toxicity and proteome profiling analysis". Nanotoxicology 8 5 (2014): 521-532. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000328126900005&KeyUID=WOS:000328126900005.
    10.3109/17435390.2013.802821
  102. Conde, Joao; Rosa, Joao; de la Fuente, Jesus M.; Baptist, Pedro V.. "Gold-nanobeacons for simultaneous gene specific silencing and intracellular tracking of the silencing events". Biomaterials 34 10 (2013): 2516-2523. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000315545500013&KeyUID=WOS:000315545500013.
    10.1016/j.biomaterials.2012.12.015
  103. Conde, J.; Ambrosone, A.; Hernandez, Y.; Marchesano, V.; Tian, F.; Ricardo Ibarra, M.; Baptista, P. V.; Tortiglione, C.; de la Fuente, J. M.. "Designing gold nanoparticles for in vivo gene silencing as a new therapeutic tool". Human Gene Therapy 24 12 (2013): A24-A24. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000328417900070&KeyUID=WOS:000328417900070.
  104. Conde, Joao; Tian, Furong; Hernandez, Yulan; Bao, Chenchen; Cui, Daxiang; Janssen, Klaus-Peter; Ricardo Ibarra, M.; et al. "In vivo tumor targeting via nanoparticle-mediated therapeutic siRNA coupled to inflammatory response in lung cancer mouse models". Biomaterials 34 31 (2013): 7744-7753. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000323459100019&KeyUID=WOS:000323459100019.
    10.1016/j.biomaterials.2013.06.041
  105. Sanz, Vanesa; Conde, Joao; Hernandez, Yulan; Baptista, Pedro V.; Ibarra, M. R.; de la Fuente, Jesus M.. "Effect of PEG biofunctional spacers and TAT peptide on dsRNA loading on gold nanoparticles". Journal of Nanoparticle Research 14 6 (2012): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000305328900032&KeyUID=WOS:000305328900032.
    10.1007/s11051-012-0917-2
  106. Conde, Joao; Ambrosone, Alfredo; Sanz, Vanesa; Hernandez, Yulan; Marchesano, Valentina; Tian, Furong; Child, Hannah; et al. "Design of Multifunctional Gold Nanoparticles for In Vitro and In Vivo Gene Silencing". Acs Nano 6 9 (2012): 8316-8324. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000309040600085&KeyUID=WOS:000309040600085.
    10.1021/nn3030223
  107. Rosa, J.; Conde, J.; de la Fuente, J. M.; Lima, J. C.; Baptista, P. V.. "Gold-nanobeacons for real-time monitoring of RNA synthesis". Biosensors & Bioelectronics 36 1 (2012): 161-167. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000305667700026&KeyUID=WOS:000305667700026.
    10.1016/j.bios.2012.04.006
  108. Garcia-Leston, J.; Roma-Torres, J.; Vilares, M.; Pinto, R.; Prista, J.; Teixeira, J. P.; Mayan, O.; et al. "Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair". Environment International 43 (2012): 29-36. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000304582800005&KeyUID=WOS:000304582800005.
    10.1016/j.envint.2012.03.001
  109. Sanz, Vanesa; Conde, Joao; Ambrosone, Alfredo; Hernandez, Yulan; Marchesasno, Valentina; Estrada, Giovani G.; Ibarra, Manuel R.; et al. "Multifunctional gold nanoparticles for gene silencing". Abstracts of Papers of the American Chemical Society 243 (2012): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000324475104058&KeyUID=WOS:000324475104058.
  110. Conde, J.; Baptista, P. V.; Hernandez, Y.; Sanz, V.; de la Fuente, J. M.. "Modification of plasmid DNA topology by 'histone-mimetic' gold nanoparticles". Nanomedicine 7 11 (2012): 1657-1666. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000311329700011&KeyUID=WOS:000311329700011.
    10.2217/nnm.12.21
  111. Conde, Joao; Rosa, Joao; Lima, Joao C.; Baptista, Pedro V.; Conde, João; Rosa, João; Lima, João C.; Baptista, Pedro V.. "Nanophotonics for Molecular Diagnostics and Therapy Applications". International Journal of Photoenergy (2012): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000296876200001&KeyUID=WOS:000296876200001.
    10.1155/2012/619530
  112. Conde, Joao; Doria, Goncalo; de la Fuente, Jesus M.; Baptista, Pedro Viana. "RNA quantification using noble metal nanoprobes: simultaneous identification of several different mRNA targets using color multiplexing and application to cancer diagnostics". Methods in molecular biology (Clifton, N.J.) 906 (2012): 71-87. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:22791425&KeyUID=MEDLINE:22791425.
    10.1007/978-1-61779-953-2_6
  113. Conde J; Doria G; Baptista P; Conde, Joao; Doria, Goncalo; Baptista, Pedro; Veigas, Bruno; et al. "Noble metal nanoparticles applications in cancer.". Journal of drug delivery 2012 2 (2011): 751075-751075. http://europepmc.org/abstract/med/22007307.
    10.1155/2012/751075
  114. Pinheiro, A. Vidal; Conde, J.; Parola, A. J.; Lima, J. C.; Baptista, P. V.. "Use of cyclodextrins as scavengers of inhibitory photo-products in light controlled in vitro synthesis of RNA". Journal of Photochemistry and Photobiology a-Chemistry 213 2-3 (2010): 147-151. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000280623200010&KeyUID=WOS:000280623200010.
    10.1016/j.jphotochem.2010.05.014
  115. Conde, Joao; de la Fuente, Jesus M; Baptista, Pedro V. "RNA quantification using gold nanoprobes - application to cancer diagnostics.". Journal of nanobiotechnology 8 (2010): 5-5. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:20181241&KeyUID=MEDLINE:20181241.
    10.1186/1477-3155-8-5
  116. Conde, J.; de la Fuente, J. M.; Baptista, P. V.. "In vitro transcription and translation inhibition via DNA functionalized gold nanoparticles". Nanotechnology 21 50 (2010): 6-6. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000284624500001&KeyUID=WOS:000284624500001.
    10.1088/0957-4484/21/50/505101
  117. Conde, Joao; Silva, Susana N.; Azevedo, Ana P.; Teixeira, Valdemar; Pina, Julieta Esperanca; Rueff, Jose; Gaspar, Jorge F.. "Association of common variants in mismatch repair genes and breast cancer susceptibility: a multigene study". Bmc Cancer 9 (2009): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000271124600002&KeyUID=WOS:000271124600002.
    10.1186/1471-2407-9-344
Thesis / Dissertation
  1. Amorim, Joana Ramos Nunes de. "Polymeric nanoparticles for local delivery of multicolor genetic circuits in breast cancer". Master, 2022. http://hdl.handle.net/10362/146084.
Website
  1. Conde, João. Conde NanoLAB. 2020. https://www.conde-nanolab.com/.

Intellectual property

Patent
  1. Conde, João. 2020. "Functionalized Nanoparticles and Compositions for Cancer Treatment and Methods". United States.
    Pending
  2. Conde, João. 2020. "Hydrogel Particles, Compositions, and Methods". United States.
    Pending
  3. Conde, João. 2019. "TRPV2 Antagonists". Portugal.
    Pending
  4. Conde, João. 2017. "Micro-rna delivery compositions, devices, and methods". United States.
    Granted/Issued
  5. Conde, João. 2017. "Rna triple helix structures, compositions, and methods". United States.
    Granted/Issued
  6. Conde, João. 2017. "Hydrogel particle of cystamine cross-linked dextran aldehyde containing imine conjugated doxorubicin and rgd peptide for chemotherapy". United States.
    Pending
  7. Conde, João. 2016. "Theranostic Nanoprobes for Overcoming Cancer Multidrug Resistance and Methods". United States.
    Pending

Other

Other output
  1. Trends in Cancer Cover image. 2021. Bárbara B. Mendes; Conde, João; Diana P. Sousa; Conniot, João.
  2. Cisplatin-Triggered Bioorthogonal Decaging of Amide Bonds for Targeted-Drug Activation in vivo. 2018. Stenton B; Oliveira B; Conde J; Negrão M; Godinho Ferreira M; Fior R; Bernardes G. http://europepmc.org/abstract/PPR/PPR61887.
    10.26434/chemrxiv.7327904.v1
  3. Editorial: Cancer Nanotheranostics: What Have We Learned So Far?. Frontiers in Chemistry. 2016. Conde, João; Tian, Furong; de la Fuente, Jesus M.; Baptista, Pedro Miguel Ribeiro Viana; Conde, Joao; Tian, Furong; de la Fuente, Jesus M.; et al. http://hdl.handle.net/10362/23358.
    https://doi.org/10.3389/fchem.2015.0071
  4. Nanomaterials for reversion of multidrug resistance in cancer: a new hope for an old idea?. Frontiers in pharmacology. 2013. Conde, João; de la Fuente, Jesus M.; Baptista, Pedro Viana; Conde, Joao; de la Fuente, Jesus M; Baptista, Pedro V. http://hdl.handle.net/10362/106984.
    https://doi.org/10.3389/fphar.2013.00134
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/07/01 Biotech in Action S2: Water Cooler Talk - Massachusetts Institute of Technology (MIT), Harvard–MIT Division for Health Sciences and Technology, July 2021, Boston, Massachusetts, USA (Invited). Biotech in Action S2: Water Cooler Talk
Massachusetts Institute of Technology (MIT), Harvard–MIT Division for Health Sciences and Technology (Boston, United States)
2021/06/01 “The story behind my path in Cancer NanoMedicine” at the PostDoc ShowCase 2nd edition - Department of Pharmacy, University of Naples Federico II, June 2021, Italy (Invited). PostDoc ShowCase 2nd edition
Department of Pharmacy, University of Naples (Napoli, Italy)
2021/05/01 9th Session IST- MedNetworking – To see or not to see: How Nanotechnology is redefining Medicine, Instituto Superior Técnico (IST), May 2021, Portugal (Invited). 9th Session IST- MedNetworking – To see or not to see: How Nanotechnology is redefining Medicine
Instituto Superior Técnico (IST) (Lisbon, Portugal)
2020/01/01 Keynote Speaker - 13º Encontro Nacional de Química Orgânica/6º Encontro Nacional de Química Terapêutica (13ENQO/6ENQT), January 2020, Portugal (Invited). Keynote Speaker - 13º Encontro Nacional de Química Orgânica/6º Encontro Nacional de Química Terapêutica (13ENQO/6ENQT)
Universidade de Aveiro (Aveiro, Portugal)
2020/01 Why going Nano on Cancer Healthcare? 13º Encontro Nacional de Química Orgânica/6º Encontro Nacional de Química Terapêutica (13ENQO/6ENQT)
(Aveiro)
2017/03 CANCER : inviting BIOMATERIALS to waltz with the devil Seminar
University of Glasgow, Institute of Molecular Cell and Systems Biology (Glasgow, United Kingdom)
2017/02 Smart Biomaterials for Cancer Nanomedicine Nanomedicine Seminars
Trinity College Dublin, School of Medicine (Dublin, Ireland)
2016/03 The Nano versus Cancer Seminar
Massachusetts Institute of Technology (Cambridge, Massachusetts , United States)
2012/02 Cancer Theranostics: Multifunctional Gold Nanoparticles for Diagnosis and Therapy Miami 2012 Winter Symposium: Nanotechnology in Biomedicine
Nature Conferences (Miami, United States)
2009 Genetic polymorphisms involved in sporadic Breast cancer XXXIV Genetic Journeys
Human Cancer Genetics and Genotoxicity, Portuguese Society of Human Genetics (Lisboa, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022 - 2022 In vitro recapitulation of breast tumor microenvironment for personalized theranostic strategies
Supervisor
 Biomedicina (associação) (PhD)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2022 - 2022 Polymeric nanoparticles for local delivery of multicolor genetic circuits in breast cancer
Supervisor
 Investigação Biomédica (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2021 - 2021 Gold-nanoconjugates as an approach to target microRNAs and immune-infiltrating cells involved in lung cancer progression
Supervisor
 Biomedicina (associação) (PhD)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2021 Transcriptional Program Biosensors for Human Cell Type and State Diagnosis
(Thesis) Arguer
 Benilde Francisco Pondeca (PhD)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020 Theranostic Nanocomposites for Cancer Immunotherapy
(Thesis) Main arguer
 Tomás Bauleth-Ramos (PhD)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Association member

Society Organization name Role
2020 - Current Global Burden Disease (GBD), Institute for Health Metrics and Evaluation (IHME), University of Washington (US). Active collaborator

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2021 "Na quimioterapia só 5% a 10% do fármaco chega ao local. Na nanotecnologia não há dispersão, é mais eficaz e menos tóxico" João Conde, professor de Genética, investigador do Centro de Estudos de Ciências Médicas (ToxOmics), da Faculdade de Ciências Médicas, Universidade Nova de Lisboa, defende que as farmacêuticas devem apoiar a investigação e que a nanomedicina é uma aposta de futuro. Jornal de Noticias

Journal scientific committee

Journal title (ISSN) Publisher
2021 - Current Journal of Functional Biomaterials MDPI
2021 - Current Materials MDPI
2021 - Current Exploration Wiley
2021 - Current VIEW Wiley
2021 - Current Frontiers Genetics - Toxicogenomics Frontiers
2020 - Current Journal of Nanotheranostics MDPI
2016 - Current Nano Biomedicine and Engineering Journal
2015 - Current Frontiers in Bioengineering and Biotechnology
2015 - Current Frontiers in Molecular Biosciences (2296-889X) Frontiers Media SA
2015 - Current Frontiers in Materials (2296-8016) Frontiers Media SA
2014 - Current Frontiers in Chemistry (2296-2646) Frontiers Media SA
Distinctions

Award

2023 2023 World Top 2% Scientists list by Stanford University
Stanford University, United States
2022 World Top 2% Scientists list by Stanford University
Stanford University, United States
2021 Nanomaterials 2020 Young Investigator Award
Multidisciplinary Digital Publishing Institute AG, Switzerland
2021 Top2% Most cited in Nanoscience/Nanotechnology
Public Library of Science, United States
2020 Biomaterials Science Emerging Investigator
2019 ERC Starting Grant - European Research Council
European Research Council, Belgium
2018 Junior Investigator: FCT Stimulus of Scientific Employment
2017 Wellcome Image Awards 2017: Wellcome Trust, UK
2016 Nano-Micro Letters Researcher Award, Nature Research Society
2016 National Cancer Institute Image award: Cancer close up, USA
2014 Marie Curie International Outgoing Fellowship for Career Development, Marie Sklodowska- Curie actions (FP7-PEOPLE-2013-IOF)
2009 PhD Fellowship - National Science Foundation Portugal - PhD Grant (FCT, SFRH/BD/ 62957/2009)