Elisabete Cristina da Rocha Costa (B314-4CF0-6633)

Curriculum Vitae

Elisabete Cristina da Rocha Costa

Elisabete Costa (Ciência ID # B314-4CF0-6633) obtained her BSc (grade 14/20; in 2012) and MSc (grade 17/20; in 2013) in Biomedical Sciences at the University of Beira Interior (UBI). In 2013, she received an MSc research grant (UBI -Banco Santander/Totta) and in 2014 another MSc research grant (CENTRO -07-ST24-FEDER-002014, Programa Operacional Regional do Centro 2007-2013 QREN). In 2015, EC started her PhD in Biochemistry at UBI (PhD grant from FCT - SFRH/BD/103507/2014), under the supervision of Professor Ilídio J. Correia at Centro de Investigação em Ciências da Saúde (CICS-UBI). Her public defense of the PhD thesis took place in December 2019 and she received the final grade Excellent. Until then, all of EC 's research work was conducted within the Biopharmaceuticals and Biomaterials Research Group (CICS-UBI) and focused on: i) the development and characterization of 2D and 3D in vitro models that better mimic human tissues; ii) the analysis and characterization of the effect of compounds in 2D and 3D cell cultures; iii) the optimization and development of protocols to study 2D and 3D cell cultures. In addition, EC has participated in research aimed at the production and characterization of scaffolds for tissue engineering (TE). EC was a contracted PhD researcher at the Instituto Politécnico da Guarda (IPG) and developed her work at the Unidade de Investigação para o Desenvolvimento do Interior (UDI), being mainly involved in researching waste and natural resources for 3D scaffold fabrication and contributing to the WasteSilk project (PTDC/BTA-BTA/0696/2020). Currently, she is an Assistant Professor at the UBI. To date, EC has collaborated with more than 35+ researchers. She is the author of 37 articles in journals indexed in Journal Citation Reports and 1 book chapter. According to Scopus, her h-factor is 28 and she has a total of 2625 citations. She also has filed 3 patents. EC has been involved in organizing 2 national meetings and has presented her work (41 posters, 8 oral presentations, 4 best poster awards) at several scientific meetings. During her career, EC has been a member of 5 research projects (CENTRO -01-0145-FEDER-037956, PTDC/NAN- MAT /28989/2017, PTDC/EMD-EMD/31462/2017, PTDC/BTA-BTA/0696/2020, and 2022.10862.PTDC). EC also had the opportunity to teach several curricular units (Biochemistry, Biomaterials and Tissue Engineering) to different BSc and MSc degrees. She co-supervised 6 Masters students and supervised 9 undergraduate students (projects covering several TE subjects) and was the opponent in 12 BSc projects. In 2021, she was recognized as the "World's TOP 2% Scientist" (DOI: 10.17632/btchxktzyw.3).

Read full resume ↓

Identification

Personal identification

Full name: Elisabete Cristina da Rocha Costa
Date of birth: 1990/04/04
Gender: Female

Citation names

Elisabete C. Costa
Costa, Elisabete C.
Costa, E. C.

Author identifiers

Ciência ID: B314-4CF0-6633
ORCID iD: 0000-0002-0490-0095
Scopus Author Id: 55805850100

Email addresses

ecrc@ipg.pt (Professional)
elisabeterochacosta@gmail.com (Personal)

Addresses

Av. Dr. Francisco Sá Carneiro 50, 6300-559, Guarda, Guarda, Portugal (Professional)

Websites

www.researchgate.net/profile/Elisabete-Costa (Professional)

Knowledge fields

Engineering and Technology - Materials Engineering
Engineering and Technology - Medical Engineering
Medical and Health Sciences - Medical Biotechnology - Biomaterials
Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
Natural sciences - Biological Sciences - Biochemistry
Engineering and Technology - Nano-technology

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Intermediate (B1)	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)

Education

	Degree	Classification
2015 - 2019/12/02 Concluded	Bioquímica (Doutoramento) Major in Tissue Engineering Universidade da Beira Interior, Portugal "Study of 3D tumor spheroids for biomedical applications" (THESIS/DISSERTATION)	Excellent
2011 - 2013/07/23 Concluded	Ciências Biomédicas (Mestrado) Major in Tissue Engineering Universidade da Beira Interior, Portugal "In vitro cell co-culture models for development of new drug delivery systems (“Modelos de co-culturas de células in vitro para desenvolvimento de novos sistemas de entrega de fármacos”)" (THESIS/DISSERTATION)	17/20
2012/09/11 - 2012/09/14 Concluded	Young researchers Training (Outros) Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal	16/20
2008 - 2012/07/10 Concluded	Ciências Biomédicas (Licenciatura) Universidade da Beira Interior, Portugal	14/20

Affiliation

Science

	Category Host institution	Employer
2022/01 - 2022/11	Contracted Researcher (Research)	Instituto Politécnico da Guarda, Portugal
	Instituto Politécnico da Guarda, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2023/01 - Current	Invited Assistant Professor (University Teacher)	Universidade da Beira Interior, Portugal
	Universidade da Beira Interior, Portugal

Others

	Category Host institution	Employer
2015/07/01 - 2019/06/30	PhD scholarship: SFRH/BD/103507/2014, Fundação para a Ciência e a Tecnologia (FCT).	Universidade da Beira Interior, Portugal
	Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2014/09/01 - 2015/08/31	MSc research grant: CENTRO-07-ST24-FEDER-002014, Programa Operacional Regional do Centro 2007-2013 QREN (Programa “Mais Centro”).	Universidade da Beira Interior, Portugal
	Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2013/09/01 - 2014/05/30	MSc research grant: UBI-Banco Santander/Totta.	Universidade da Beira Interior, Portugal
	Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal

Projects

Contract

	Designation	Funders
2023/01/01 - 2024	Use of MIcroAlgae in Drug inToxications: a new solution 2022.10862.PTDC Researcher	Fundação para a Ciência e a Tecnologia
2018/07 - 2022/07	INEYE: Non-invasive ocular insert for drug delivery PTDC/EMD-EMD/31462/2017 Researcher Universidade de Coimbra, Portugal Universidade da Beira Interior, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/04 - 2022/04	ZAPGO: Zwitterionic-based amphiphile coated Graphene Oxide nanostructures for chemophotothermal therapy of breast cancer PTDC/NAN-MAT/28989/2017 Researcher Universidade da Beira Interior, Portugal Instituto Politécnico da Guarda, Portugal Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022 - 2022	WASTESILK: Silk Sericin as an industrial wastewater with valuable biomedical potential. PTDC/BTA-BTA/0696/2020 Researcher
2018/06 - 2020/05	KitoVera: Filme/Película para aplicação tópica no tratamento de lesões da pele e método para sua obtenção e aplicação CENTRO-01-0145-FEDER-037956 Researcher Universidade da Beira Interior, Portugal	European Regional Development Fund Concluded

Outputs

Publications

Book chapter	Gaspar, Vítor M.; Moreira, André F.; de Melo-Diogo, Duarte; Costa, Elisabete C.; Queiroz, João A.; Sousa, Fani; Pichon, Chantal; Correia, Ilídio J.. "Multifunctional nanocarriers for codelivery of nucleic acids and chemotherapeutics to cancer cells". In Nanobiomaterials in Medical Imaging, 163-207. Elsevier, 2016. Published • 10.1016/b978-0-323-41736-5.00006-6
Conference poster	"Duarte de Melo-Diogo, Elisabete C. Costa, Cátia G. Alves, Rita Lima-Sousa, Paula Ferreira, Ricardo O- Louro and Ilídio J. Correia, POxylated Graphene Oxide for cancer phototherapy and combinatorial drug delivery.". Paper presented in 5th Edition of the European Graphene Forum, 2019. "Rita Lima-Sousa, Duarte de Melo-Diogo, Cátia G. Alves, Elisabete C. Costa, Paula Ferreira, Ricardo O. Louro, António G. Mendonça and Ilídio J. Correia, Environmentally-friendly reduced graphene oxide functionalized with hyaluronic acid for targeted cancer photothermal therapy.". Paper presented in 5th Edition of the European Graphene Forum, 2019. "Cátia G. Alves, Duarte de Melo-Diogo, Rita Lima-Sousa, Elisabete C. Costa and Ilídio J. Correia, Hyaluronic Acid-based Micelles loaded with IR780 and DOX for Targeted Cancer Chemo-Photothermal Therapy.". Paper presented in Encontro com a Ciência e Tecnologia, 2019. "Rita Lima-Sousa, Duarte de Melo-Diogo, Cátia G. Alves, Elisabete C. Costa, Paula Ferreira, Ricardo O. Louro, António G. Mendonça and Ilídio J. Correia, Hyaluronic acid functionalized reduced graphene oxide nanomaterials for targeted cancer photothermal therapy.". Paper presented in Encontro com a Ciência e Tecnologia, 2019. "Daniel N. Silva, Elisabete C. Costa, André F. Moreira, Duarte de Melo-Diogo and Ilídio J. Correia, Optical clearing techniques to 3D spheroids for the imaging through CLSM.". Paper presented in XIV Annual CICS-UBI Symposium, 2019. "Cátia G. Alves, Duarte de Melo-Diogo, Rita Lima-Sousa, Elisabete C. Costa and Ilído J. Correia, Co-encapsulation of IR780 and DOX in Hyaluronic Acid Functionalized Micelles for Targeted Cancer Chemo-phototherapy.". Paper presented in XIV Annual CICS-UBI Symposium, 2019. "Rita Lima-Sousa, Duarte de Melo-Diogo, Cátia G. Alves, Elisabete C. Costa, Paula Ferreira, Ricardo O. Louro and Ilídio J. Correia, Breast Cancer Targeted Photothermal Therapy Mediated By Hyaluronic Acid Functionalized Reduced Graphene Oxide.". Paper presented in XIV Annual CICS-UBI Symposium, 2019. "Cátia G. Alves, Duarte de Melo-Diogo, Rita Lima-Sousa, Elisabete C. Costa and Ilídio J. Correia, IR780 and DOX loaded hyaluronic acid-based micelles for targeted cancer chemo-phototherapy.". Paper presented in 6th IEEE Portuguese Meeting on Bioengineering, 2019. "Daniel N. Silva, Elisabete C. Costa, André F. Moreira, Duarte de Melo-Diogo and Ilídio J. Correia, Optical clearing techniques for the imaging of 3D spheroids.". Paper presented in 6th IEEE Portuguese Meeting on Bioengineering, 2019. "Rita Lima-Sousa, Duarte de Melo-Diogo, Cátia G. Alves, Elisabete C. Costa and Ilídio J. Correia, Targeted cancer photothermal therapy using hyaluronic acid functionalized green reduced graphene oxide.". Paper presented in 6th IEEE Portuguese Meeting on Bioengineering, 2019. "Ana S. Barros, Elisabete C. Costa, Ana S. Nunes, Duarte de Melo-Diogo and Ilídio J. Correia, Comparative study of the therapeutic effect of Doxorubicin and Resveratrol combination on 2D and 3D (spheroids) cell culture models.". Paper presented in XIII Annual CICS-UBI Symposium, 2018. "Ana S. Nunes, Elisabete C. Costa, Ana S. Barros, Duarte de Melo-Diogo and Ilídio J. Correia, Gathering 2D cell cultures derived from 3D MCF-7 spheroids displaying a Doxorubicin resistant profile.". Paper presented in XIII Annual CICS-UBI Symposium, 2018. "Cátia G. Alves, Duarte de Melo-Diogo, Rita Lima-Sousa, Elisabete C. Costa and Ilídio J. Correia, Formulation of hyaluronic acid-based micelles loaded with IR780 for cancer therapy.". Paper presented in XIII Annual CICS-UBI Symposium, 2018. "Rita Lima-Sousa, Duarte de Melo-Diogo, Cátia G. Alves, Elisabete C. Costa, Ricardo O. Louro and Ilídio J. Correia, Environmentally-friendly reduction and functionalization of graphene oxide based nanomaterials for cancer therapy.". Paper presented in XIII Annual CICS-UBI Symposium, 2018. "André F. Moreira, Diana R. Dias, Carolina F. Rodrigues, Catarina A. Reis, Elisabete C. Costa and Ilídio J. Correia, Nano-in-micro spheres for pH- and thermo-responsive drug delivery to cancer cells.". Paper presented in Encontro com a Ciência e Tecnologia 2018, 2018. "André F. Moreira, Diana R. Dias, Elisabete C. Costa and Ilídio J. Correia, Dual-stimuli responsive nano-in-micro drug delivery systems for cancer therapy.". Paper presented in Encontro com a Ciência e Tecnologia 2017, 2017. "Duarte de Melo-Diogo, Cleide Pais-Silva, Elisabete C. Costa, Ricardo O. Louro and Ilídio J. Correia, Nanographene oxide functionalized with PEGylated vitamin E for breast cancer therapy.". Paper presented in Encontro com a Ciência e Tecnologia 2017, 2017. "Elisabete C. Costa, Marco P. Carvalho, Duarte de Melo-Diogo, André F. Moreira and Ilídio J. Correia, Mimicking breast cancer microenvironment with in vitro 3D heterotypic spheroids.". Paper presented in Encontro com a Ciência e Tecnologia 2017, 2017. "André F. Moreira, Diana R. Dias, Elisabete C. Costa and Ilídio J. Correia, Nano-in-micro particles for stimuli responsive drug delivery to cancer cells.". 2017. "Duarte de Melo-Diogo, Cleide Pais-Silva, Elisabete C. Costa, Ricardo O. Louro and Ilídio J. Correia, PEGylated vitamin E functionalized nanographene oxide for breast cancer therapy.". Paper presented in II International Congress in Health Sciences Research Towards Innovation and Entrepreneurship: Trends in Biotechnology for Biomedical Applications, 2017. "Elisabete C. Costa, Marco P. Carvalho, Duarte de Melo-Diogo, André F. Moreira and Ilídio J. Correia, Mimicking breast cancer microenvironment with in vitro 3D co-culture models.". Paper presented in II International Congress in Health Sciences Research Towards Innovation and Entrepreneurship: Trends in Biotechnology for Biomedical Applications, 2017. "Duarte de Melo-Diogo, Cleide Pais-Silva, Elisabete C. Costa, Ricardo O. Louro and Ilídio J. Correia, Functionalization of graphene oxide for anticancer applications. (best poster award)". Paper presented in V Ciclo de Conferências da Faculdade de Ciências, 2017. "Marco P. Carvalho, Elisabete C. Costa and Ilídio J. Correia, Hyaluronic acid biomaterial application in breast cancer spheroids assembly.". Paper presented in V Encontro de Estudantes de Materiais (ENEM), 2016. "André F. Moreira, Vítor M. Gaspar, Elisabete C. Costa, Duarte de Melo-Diogo, Paulo Machado, Catarina M. Paquete and Ilídio J. Correia, Calcium carbonate coated nanoparticles for pH responsive drug co-delivery to prostate cancer cells.". Paper presented in Encontro com a Ciência e Tecnologia 2016, 2016. "Marco P. Carvalho, Elisabete C. Costa and Ilídio J. Correia, Assembly of breast cancer spheroids. (best poster award)". Paper presented in X Annual CICS Symposium, 2015. "André F. Moreira, Vítor M. Gaspar, Elisabete C. Costa, Duarte de Melo-Diogo, Paulo Machado, Catarina M. Paquete and Ilídio J. Correia, Calcium carbonate coated nanoparticles for pH-responsive drug co-delivery to prostate cancer cells.". Paper presented in VIII Jornadas sobre Tecnologia e Saúde, 2015. "Duarte de Melo-Diogo, D., Vítor M. Gaspar, Elisabete C. Costa, André F. Moreira, David Oppolzer, Eugénia Gallardo and Ilídio J. Correia, Triple-drug co-delivery by TPGS-PLA micelles for lung cancer therapy.". Paper presented in VIII Jornadas sobre Tecnologia e Saúde, 2015. "Elisabete C. Costa, Vítor M. Gaspar, Duarte de Melo-Diogo, André F. Moreira, João G. Marques, Paula Coutinho, Ilídio J. Correia, Optimization of Liquid Overlay Technique (LOT) to produce 3D breast and cervical co-culture models. (best poster award)". Paper presented in VIII Jornadas sobre Tecnologia e Saúde, 2015. "André F. Moreira, Vítor M. Gaspar, Elisabete C. Costa, Duarte de Melo-Diogo, Paulo Machado, Catarina M. Paquete and Ilídio J. Correia, pH-sensitive mesoporous silica nanoparticles for drug delivery to prostate cancer cells.". Paper presented in Semana da Ciência, 2014. "Duarte de Melo-Diogo, Vítor M. Gaspar, Elisabete C. Costa, André F. Moreira, David Oppolzer, Eugénia Gallardo and Ilídio J. Correia, Triple drug loaded polymeric micelles for improved lung cancer therapy.". Paper presented in Semana da Ciência, 2014. "Elisabete C. Costa, Vítor M. Gaspar, Duarte de Melo-Diogo, André F. Moreira, Paula Coutinho and Ilídio J. Correia, Liquid Overlay Technique (LOT) optimizations for spheroids 3D cell culture.". Paper presented in Semana da Ciência, 2014. "André F. Moreira, Vitor M. Gaspar, Elisabete C. Costa, Duarte de Melo-Diogo, Paulo Machado, Catarina M. Paquete and Ilídio J. Correia, Development of mesoporous silica nanoparticles for drug delivery to cancer cells.". Paper presented in IX Annual CICS Symposium, 2014. "Elisabete C. Costa, Vítor M. Gaspar, Duarte de Melo-Diogo, André F. Moreira, João G. Marques, Paula Coutinho and Ilídio J. Correia, Co-cultures for nanoparticles uptake analysis.". Paper presented in IX Annual CICS Symposium, 2014. "João G. Marques, Vítor M. Gaspar, David Markl, Elisabete C. Costa, Duarte de Melo-Diogo, André F. Moreira, Eugénia Gallardo and Ilídio J. Correia, Co-delivery of a dual drug combination in polymeric nanovehicles for improved anticancer therapy.". Paper presented in IX Annual CICS Symposium, 2014. "André F. Moreira, Vítor M. Gaspar, Elisabete C. Costa, Duarte de Melo-Diogo, Paulo Machado, Catarina M. Paquete and Ilídio J. Correia, Synthesis and characterization of MCM-41 type silica nanoparticles by a Stöber modified metho.". Paper presented in Encontro Bienal das Divisões Técnicas da Sociedade Portuguesa de Materiais (SPM), 2014. "Elisabete C. Costa, Vítor M. Gaspar, Duarte de Melo-Diogo, André F. Moreira, João G. Marques, Paula Coutinho and Ilídio J. Correia, Evaluation of nanoparticles uptake in breast cancer co-cultures.". Paper presented in Encontro Bienal das Divisões Técnicas da Sociedade Portuguesa de Materiais (SPM), 2014. "Vítor M. Gaspar, Elisabete C. Costa, João A. Queiroz, Chantal Pichon, Fani Sousa and Ilídio Correia, Evaluation of targeted gene delivery to cancer cells trough high throughput fluorescence microscopy.". Paper presented in Encontro Bienal das Divisões Técnicas da Sociedade Portuguesa de Materiais (SPM), 2014. "David Oppolzer, João G. Marques, Duarte de Melo-Diogo, Vítor M. Gaspar, Elisabete C. Costa, Eugenia Gallardo and Ilídio J. Correia, Simultaneos determination of Sildenafil and Crizotinib using HPLC-DAD.". Paper presented in 8º Encontro Nacional de Cromatografia, 2013. "Vítor M. Gaspar, Elisabete C. Costa, João G. Marques, João A. Queiroz, Chantal Pichon, Fani Sousa and Ilídio Correia, Evaluation of targeted gene delivery to cancer cells trough high throughput fluorescence microscopy.". Paper presented in 1st POLARIS Workshop International Conference, 2013. "João G. Marques, Vítor M. Gaspar, Elisabete C. Costa, Catarina M. Paquete and Ilídio J. Correia, Development of micelles as carriers of non-steroidal anti-inflammatory drugs (NSAID) for application in breast cancer therapy.". Paper presented in VIII Annual CICS Symposium, 2013. "Elisabete C. Costa, Vítor M. Gaspar, João G. Marques, Paula Coutinho and Ilídio J. Correia, Mimicking breast cancer microenvironment with in vitro co-culture models. (best poster award)". Paper presented in VI Jornadas sobre Tecnologia e Saúde, 2013.
Journal article	Silva, Daniel N.; Costa, Elisabete C.; Rodrigues, Carolina F.; de Melo-Diogo, Duarte; Correia, Ilídio J.; Moreira, André F.. "Influence of ClearT and ClearT2 Agitation Conditions in the Fluorescence Imaging of 3D Spheroids". International Journal of Molecular Sciences 22 1 (2020): 266. http://dx.doi.org/10.3390/ijms22010266. Published • 10.3390/ijms22010266 Jacinto, Telma A.; Rodrigues, Carolina F.; Moreira, André F.; Miguel, Sónia P.; Costa, Elisabete C.; Ferreira, Paula; Correia, Ilídio J.. "Hyaluronic acid and vitamin E polyethylene glycol succinate functionalized gold-core silica shell nanorods for cancer targeted photothermal therapy". Colloids and Surfaces B: Biointerfaces 188 (2020): 110778. http://dx.doi.org/10.1016/j.colsurfb.2020.110778. Published • 10.1016/j.colsurfb.2020.110778 Moreira, André F.; Rodrigues, Carolina F.; Jacinto, Telma A.; Miguel, Sónia P.; Costa, Elisabete C.; Correia, Ilídio J.. "Poly (vinyl alcohol)/chitosan layer-by-layer microneedles for cancer chemo-photothermal therapy". International Journal of Pharmaceutics 576 (2020): 118907. http://dx.doi.org/10.1016/j.ijpharm.2019.118907. Published • 10.1016/j.ijpharm.2019.118907 Moreira, André F.; Rodrigues, Carolina F.; Jacinto, Telma A.; Miguel, Sónia P.; Costa, Elisabete C.; Correia, Ilídio J.. "Microneedle-based delivery devices for cancer therapy: A review". Pharmacological Research 148 (2019): 104438. http://dx.doi.org/10.1016/j.phrs.2019.104438. Published • 10.1016/j.phrs.2019.104438 Costa, Elisabete C.; Silva, Daniel N.; Moreira, André F.; Correia, Ilídio J.. "Optical clearing methods: An overview of the techniques used for the imaging of 3D spheroids". Biotechnology and Bioengineering 116 10 (2019): 2742-2763. http://dx.doi.org/10.1002/bit.27105. Published • 10.1002/bit.27105 Alves, Cátia G.; de Melo-Diogo, Duarte; Lima-Sousa, Rita; Costa, Elisabete C.; Correia, Ilídio J.. "Hyaluronic acid functionalized nanoparticles loaded with IR780 and DOX for cancer chemo-photothermal therapy". European Journal of Pharmaceutics and Biopharmaceutics 137 (2019): 86-94. http://dx.doi.org/10.1016/j.ejpb.2019.02.016. Published • 10.1016/j.ejpb.2019.02.016 Rodrigues, Carolina F.; Jacinto, Telma A.; Moreira, André F.; Costa, Elisabete C.; Miguel, Sónia P.; Correia, Ilídio J.. "Functionalization of AuMSS nanorods towards more effective cancer therapies". Nano Research 12 4 (2019): 719-732. http://dx.doi.org/10.1007/s12274-019-2286-y. Published • 10.1007/s12274-019-2286-y Barros, Andreia S.; Costa, Elisabete C.; Nunes, Ana S.; de Melo-Diogo, Duarte; Correia, Ilídio J.. "Comparative study of the therapeutic effect of Doxorubicin and Resveratrol combination on 2D and 3D (spheroids) cell culture models". International Journal of Pharmaceutics 551 1-2 (2018): 76-83. http://dx.doi.org/10.1016/j.ijpharm.2018.09.016. Published • 10.1016/j.ijpharm.2018.09.016 Moreira, André F.; Rodrigues, Carolina F.; Reis, Catarina A.; Costa, Elisabete C.; Correia, Ilídio J.. "Gold-core silica shell nanoparticles application in imaging and therapy: A review". Microporous and Mesoporous Materials 270 (2018): 168-179. http://dx.doi.org/10.1016/j.micromeso.2018.05.022. Published • 10.1016/j.micromeso.2018.05.022 de Melo-Diogo, Duarte; Lima-Sousa, Rita; Alves, Cátia G.; Costa, Elisabete C.; Louro, Ricardo O.; Correia, Ilídio J.. "Functionalization of graphene family nanomaterials for application in cancer therapy". Colloids and Surfaces B: Biointerfaces 171 (2018): 260-275. http://dx.doi.org/10.1016/j.colsurfb.2018.07.030. Published • 10.1016/j.colsurfb.2018.07.030 Lima-Sousa, Rita; de Melo-Diogo, Duarte; Alves, Cátia G.; Costa, Elisabete C.; Ferreira, Paula; Louro, Ricardo O.; Correia, Ilídio J.. "Hyaluronic acid functionalized green reduced graphene oxide for targeted cancer photothermal therapy". Carbohydrate Polymers 200 (2018): 93-99. http://dx.doi.org/10.1016/j.carbpol.2018.07.066. Published • 10.1016/j.carbpol.2018.07.066 Nunes, Ana S.; Barros, Andreia S.; Costa, Elisabete C.; Moreira, André F.; Correia, Ilídio J.. "3D tumor spheroids as in vitro models to mimic in vivo human solid tumors resistance to therapeutic drugs". Biotechnology and Bioengineering 116 1 (2018): 206-226. http://dx.doi.org/10.1002/bit.26845. Published • 10.1002/bit.26845 Nunes, Ana S.; Costa, Elisabete C.; Barros, Andreia S.; de Melo-Diogo, Duarte; Correia, Ilídio J.. "Establishment of 2D Cell Cultures Derived From 3D MCF-7 Spheroids Displaying a Doxorubicin Resistant Profile". Biotechnology Journal 14 4 (2018): 1800268. http://dx.doi.org/10.1002/biot.201800268. Published • 10.1002/biot.201800268 Costa, Elisabete C.; Moreira, André F.; de Melo-Diogo, Duarte; Correia, Ilídio J.. "ClearT immersion optical clearing method for intact 3D spheroids imaging through confocal laser scanning microscopy". Optics & Laser Technology 106 (2018): 94-99. http://dx.doi.org/10.1016/j.optlastec.2018.04.002. Published • 10.1016/j.optlastec.2018.04.002 Moreira, André F; Rodrigues, Carolina F; Reis, Catarina A; Costa, Elisabete C; Ferreira, Paula; Correia, Ilídio J. "Development of poly-2-ethyl-2-oxazoline coated gold-core silica shell nanorods for cancer chemo-photothermal therapy". Nanomedicine 13 20 (2018): 2611-2627. http://dx.doi.org/10.2217/nnm-2018-0179. Published • 10.2217/nnm-2018-0179 de Melo-Diogo, Duarte; Costa, Elisabete C.; Alves, Cátia G.; Lima-Sousa, Rita; Ferreira, Paula; Louro, Ricardo O.; Correia, Ilídio J.. "POxylated graphene oxide nanomaterials for combination chemo-phototherapy of breast cancer cells". European Journal of Pharmaceutics and Biopharmaceutics 131 (2018): 162-169. http://dx.doi.org/10.1016/j.ejpb.2018.08.008. Published • 10.1016/j.ejpb.2018.08.008 Lamas, Miguel L.; Lima, Mafalda S.; Pinho, Ana C.; Tugushi, David; Katsarava, Ramaz; Costa, Elisabete C.; Correia, Ilídio J.; et al. "Towards the development of electrospun mats from poly(e-caprolactone)/poly(ester amide)s miscible blends". Polymer 150 (2018): 343-359. http://dx.doi.org/10.1016/j.polymer.2018.07.050. Published • 10.1016/j.polymer.2018.07.050 "Polyethylene glycol molecular weight influences the ClearT2 optical clearing method for spheroids imaging by confocal laser scanning microscopy". Journal of Biomedical Optics 23 05 (2018): 1. http://dx.doi.org/10.1117/1.jbo.23.5.055003. Published • 10.1117/1.jbo.23.5.055003 Costa, Elisabete C.; de Melo-Diogo, Duarte; Moreira, André F.; Carvalho, Marco P.; Correia, Ilídio J.. "Spheroids Formation on Non-Adhesive Surfaces by Liquid Overlay Technique: Considerations and Practical Approaches". Biotechnology Journal 13 1 (2017): 1700417. http://dx.doi.org/10.1002/biot.201700417. Published • 10.1002/biot.201700417 Carvalho, Marco P.; Costa, Elisabete C.; Correia, Ilídio J.. "Assembly of breast cancer heterotypic spheroids on hyaluronic acid coated surfaces". Biotechnology Progress 33 5 (2017): 1346-1357. http://dx.doi.org/10.1002/btpr.2497. Published • 10.1002/btpr.2497 Moreira, André F.; Dias, Diana R.; Costa, Elisabete C.; Correia, Ilídio J.. "Thermo- and pH-responsive nano-in-micro particles for combinatorial drug delivery to cancer cells". European Journal of Pharmaceutical Sciences 104 (2017): 42-51. http://dx.doi.org/10.1016/j.ejps.2017.03.033. Published • 10.1016/j.ejps.2017.03.033 de Melo-Diogo, Duarte; Pais-Silva, Cleide; Costa, Elisabete C; Louro, Ricardo O; Correia, Ilídio J. "D-a-tocopheryl polyethylene glycol 1000 succinate functionalized nanographene oxide for cancer therapy". Nanomedicine 12 5 (2017): 443-456. http://dx.doi.org/10.2217/nnm-2016-0384. Published • 10.2217/nnm-2016-0384 Costa, Elisabete C.; Moreira, André F.; de Melo-Diogo, Duarte; Gaspar, Vítor M.; Carvalho, Marco P.; Correia, Ilídio J.. "3D tumor spheroids: an overview on the tools and techniques used for their analysis". Biotechnology Advances 34 8 (2016): 1427-1441. http://dx.doi.org/10.1016/j.biotechadv.2016.11.002. Published • 10.1016/j.biotechadv.2016.11.002 Carvalho, Marco P.; Costa, Elisabete C.; Miguel, Sónia P.; Correia, Ilídio J.. "Tumor spheroid assembly on hyaluronic acid-based structures: A review". Carbohydrate Polymers 150 (2016): 139-148. http://dx.doi.org/10.1016/j.carbpol.2016.05.005. Published • 10.1016/j.carbpol.2016.05.005 Gaspar, Vítor M.; Moreira, André F.; Costa, Elisabete C.; Queiroz, João A.; Sousa, Fani; Pichon, Chantal; Correia, Ilídio J.. "Gas-generating TPGS-PLGA microspheres loaded with nanoparticles (NIMPS) for co-delivery of minicircle DNA and anti-tumoral drugs". Colloids and Surfaces B: Biointerfaces 134 (2015): 287-294. http://dx.doi.org/10.1016/j.colsurfb.2015.07.004. Published • 10.1016/j.colsurfb.2015.07.004 Gaspar, Vítor M.; Baril, Patrick; Costa, Elisabete C.; de Melo-Diogo, Duarte; Foucher, Frédéric; Queiroz, João A.; Sousa, Fani; Pichon, Chantal; Correia, Ilídio J.. "Bioreducible poly(2-ethyl-2-oxazoline)–PLA–PEI-SS triblock copolymer micelles for co-delivery of DNA minicircles and Doxorubicin". Journal of Controlled Release 213 (2015): 175-191. http://dx.doi.org/10.1016/j.jconrel.2015.07.011. Published • 10.1016/j.jconrel.2015.07.011 Gaspar, Vítor; Melo-Diogo, Duarte de; Costa, Elisabete; Moreira, André; Queiroz, João; Pichon, Chantal; Correia, Ilídio; Sousa, Fani. "Minicircle DNA vectors for gene therapy: advances and applications". Expert Opinion on Biological Therapy 15 3 (2014): 353-379. http://dx.doi.org/10.1517/14712598.2015.996544. Published • 10.1517/14712598.2015.996544 Moreira, André F.; Gaspar, Vítor M.; Costa, Elisabete C.; de Melo-Diogo, Duarte; Machado, Paulo; Paquete, Catarina M.; Correia, Ilídio J.. "Preparation of end-capped pH-sensitive mesoporous silica nanocarriers for on-demand drug delivery". European Journal of Pharmaceutics and Biopharmaceutics 88 3 (2014): 1012-1025. http://dx.doi.org/10.1016/j.ejpb.2014.09.002. Published • 10.1016/j.ejpb.2014.09.002 de Melo-Diogo, Duarte; Gaspar, Vítor M.; Costa, Elisabete C.; Moreira, André F.; Oppolzer, David; Gallardo, Eugénia; Correia, Ilídio J.. "Combinatorial delivery of Crizotinib–Palbociclib–Sildenafil using TPGS-PLA micelles for improved cancer treatment". European Journal of Pharmaceutics and Biopharmaceutics 88 3 (2014): 718-729. http://dx.doi.org/10.1016/j.ejpb.2014.09.013. Published • 10.1016/j.ejpb.2014.09.013 Gaspar, Vítor M.; Costa, Elisabete C.; Queiroz, João A.; Pichon, Chantal; Sousa, Fani; Correia, Ilídio J.. "Folate-Targeted Multifunctional Amino Acid-Chitosan Nanoparticles for Improved Cancer Therapy". Pharmaceutical Research 32 2 (2014): 562-577. http://dx.doi.org/10.1007/s11095-014-1486-0. Published • 10.1007/s11095-014-1486-0 Gaspar, Vítor M.; Gonçalves, Cristine; de Melo-Diogo, Duarte; Costa, Elisabete C.; Queiroz, João A.; Pichon, Chantal; Sousa, Fani; Correia, Ilídio J.. "Poly(2-ethyl-2-oxazoline)–PLA-g–PEI amphiphilic triblock micelles for co-delivery of minicircle DNA and chemotherapeutics". Journal of Controlled Release 189 (2014): 90-104. http://dx.doi.org/10.1016/j.jconrel.2014.06.040. Published • 10.1016/j.jconrel.2014.06.040 Marques, João G.; Gaspar, Vítor M.; Markl, David; Costa, Elisabete C.; Gallardo, Eugénia; Correia, Ilídio J.. "Co-delivery of Sildenafil (Viagra®) and Crizotinib for Synergistic and Improved Anti-tumoral Therapy". Pharmaceutical Research 31 9 (2014): 2516-2528. http://dx.doi.org/10.1007/s11095-014-1347-x. Published • 10.1007/s11095-014-1347-x Costa, Elisabete C.; Gaspar, Vítor M.; Coutinho, Paula; Correia, Ilídio J.. "Optimization of liquid overlay technique to formulate heterogenic 3D co-cultures models". Biotechnology and Bioengineering 111 8 (2014): 1672-1685. http://dx.doi.org/10.1002/bit.25210. Published • 10.1002/bit.25210 Marques, João G.; Gaspar, Vítor M.; Costa, Elisabete; Paquete, Catarina M.; Correia, Ilídio J.. "Synthesis and characterization of micelles as carriers of non-steroidal anti-inflammatory drugs (NSAID) for application in breast cancer therapy". Colloids and Surfaces B: Biointerfaces 113 (2014): 375-383. http://dx.doi.org/10.1016/j.colsurfb.2013.09.037. Published • 10.1016/j.colsurfb.2013.09.037 Costa, Elisabete C.; Gaspar, Vítor M.; Marques, João G.; Coutinho, Paula; Correia, Ilídio J.. "Evaluation of Nanoparticle Uptake in Co-culture Cancer Models". PLoS ONE 8 7 (2013): e70072. http://dx.doi.org/10.1371/journal.pone.0070072. Open access • Published • 10.1371/journal.pone.0070072

Intellectual property

Patent

2021. "Film for topical application in the treatment of skin lesions and meth-od of obtaining and applying same".
Granted/Issued
2018. "ClearF - método para a observação de culturas 3D (esferoides) marcadas com iodeto de propídio através de microscopia de confocal".
Pending
2017. "Dispositivo para produção de esferóides e avaliação de novas terapêuticas".
Pending

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2018/05/02	Duarte de Melo-Diogo, Cleide Pais-Silva, Elisabete C. Costa, Cátia G. Alves, Rita Lima-Sousa, Ricardo O. Louro and Ilídio J. Correia, Near infrared light responsive nanomaterials for cancer therapy.	VI Jornadas de Bioengenharia Universidade da Beira Interior (Covilhã, Portugal)
2018/04/23	Elisabete C. Costa, Marco P. Carvalho, André F. Moreira, Duarte de Melo-Diogo and Ilídio J. Correia, Agarose and hyaluronic acid (HA) application in 3D cell culture of breast cancer cells.	XVI Portuguese Conference on Fracture TRYP Dona Maria Hotel (Covilhã, Portugal)
2018/04/23	Duarte de Melo-Diogo, Cleide Pais-Silva, Elisabete C. Costa, Cátia G. Alves, Rita Lima-Sousa, Ricardo O. Louro and Ilídio J. Correia, Near infrared light responsive nanomaterials for cancer therapy.	XVI Portuguese Conference on Fracture TRYP Dona Maria Hotel (Covilhã, Portugal)
2015/05/06	Vítor M. Gaspar, Cristine Gonçalves, Duarte de Melo-Diogo, Elisabete C. Costa, João A. Queiroz, Chantal Pichon, Fani Sousa and Ilídio J. Correia, Polymeric nanocarriers for delivery of multiple bioactive molecules to breast cancer cells.	Biochemistry Symposium Universidade da Beira Interior (Covilhã, Portugal)
2015/02/11	Vítor M. Gaspar, Cristine Gonçalves, Duarte de Melo-Diogo, Elisabete C. Costa, João A. Queiroz, Chantal Pichon, Fani Sousa and Ilídio J. Correia, Simultaneous delivery of drugs and genes by multi-block polymeric nanomicelles for synergistic cancer therapy.	Nanoscience and Nanotechnology International Conference - NanoPT Centro de Congressos e Exposições Alfândega (Porto, Portugal)
2014/05/22	Vítor M. Gaspar, Elisabete C. Costa, João G. Marques, Ricardo O. Louro, João A. Queiroz, Fani Sousa and Ilídio J. Correia, Development of nanosystems for delivery of bioactive molecules with application in cancer therapy.	Sessão Clínica Centro Hospitalar Cova da Beira (CHCB) (Covilhã, Portugal)
2014/03/28	Elisabete C. Costa, Vítor M. Gaspar, João F.G. Marques, Paula Coutinho and Ilídio J. Correia, Mimicking cancer microenvironment with 2D and 3D in vitro co¬culture models to evaluate nanoparticles uptake.	II Encontro Nacional de Estudantes de Química (II ENEQUI) Universidade da Beira Interior, Faculdade Ciências da Saúde (Covilhã, Portugal)
2014/03/13	Vítor M. Gaspar, Elisabete C. Costa, Ricardo O. Louro, João A. Queiroz, Fani Sousa and Ilídio J. Correia, Nanomaterials for delivery of biomolecules with application in cancer therapy.	V Jornadas em Ciências Biomédicas Universidade da Beira Interior, Faculdade Ciências da Saúde (Covilhã, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2022 - Current	Application of silk proteins in tissue engineering. Co-supervisor	Farmácia (Degree) Instituto Politécnico da Guarda, Portugal
2017 - 2028	Modelos tumorais in vitro para a avaliação de fármacos. Supervisor	Biotecnologia (Degree) Universidade da Beira Interior, Portugal
2018 - 2019	Penetração de nanopartículas em modelos in vitro tumorais. Supervisor	Biotecnologia (Degree) Universidade da Beira Interior, Portugal
2018 - 2019	Desenvolvimento de culturas tridimensionais (3D) de células: influência do tamanho das nanopartículas na sua penetração em esferoides. Supervisor	Ciências Biomédicas (Degree) Universidade da Beira Interior, Portugal
2018 - 2019	Desenvolvimento de culturas tridimensionais (3D) de célula: influência do tamanho dos esferoides na penetração de nanopartículas. Supervisor	Ciências Biomédicas (Degree) Universidade da Beira Interior, Portugal
2018 - 2019	In vitro tumor models for cancer research and therapeutics evaluation (Modelos de tumor in vitro para pesquisa de cancro e avaliação terapêutica). Co-supervisor	Ciências Biomédicas (Master) Universidade da Beira Interior, Portugal
2017 - 2018	Cultura de células tumorais para a avaliação de fármacos Supervisor	Bioquímica (Degree) Universidade da Beira Interior, Portugal
2017 - 2018	2D and 3D in vitro tumor models for drug screening (Modelos tumorais 2D e 3D para a avaliação de fármacos). Co-supervisor	Ciências Biomédicas (Master) Universidade da Beira Interior, Portugal
2017 - 2018	In vitro models for drug screening purposes (Modelo tumoral in vitro para a avaliação terapêutica de fármacos). Co-supervisor	Bioquímica (Master) Universidade da Beira Interior, Portugal
2016 - 2017	Modelos in vitro para avaliação de moléculas terapêuticas Supervisor	Bioquímica (Degree) Universidade da Beira Interior, Portugal
2016 - 2017	Modelos in vitro para avaliação de fármacos. Supervisor	Biotecnologia (Degree) Universidade da Beira Interior, Portugal
2016 - 2017	In vitro models for drug screening (Modelos in vitro para rastreio de fármacos). Co-supervisor	Ciências Biomédicas (Master) Universidade da Beira Interior, Portugal
2015 - 2016	Cell culture models for drug and nanoparticles screen (Modelos de cultura celular para rastreio de fármacos) Co-supervisor	Ciências Biomédicas (Master) Universidade da Beira Interior, Portugal
2014 - 2015	Ensaios de biocompatibilidade de materiais para futuras aplicações em Engenharia de Tecidos. Co-supervisor	Bioquímica (Degree) Universidade da Beira Interior, Portugal
2014 - 2015	Development of polymeric matrices for application in skin regeneration (Desenvolvimento de matrizes poliméricas para a aplicação na regeneração da pele). Co-supervisor	Biotecnologia (Master) Universidade da Beira Interior, Portugal
2013 - 2014	Utilização de modelos in vitro e in vivo para reproduzir o microambiente tumoral: scaffolds por electrospinning e impressão 3D como suportes de co-culturas 3D. Supervisor	Bioquímica (Degree) Universidade da Beira Interior, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2018/04/23 - 2018/04/24	XVI Portuguese Conference on Fracture. (2018/04/23 - 2018/04/24) Conference (Member of the Organising Committee)	Universidade da Beira Interior, Portugal
2012/05/22 - 2012/05/22	II Simpósio em Emprego e Oportunidades em Ciências Biomédicas (2012/05/22 - 2012/05/22) Symposium (Member of the Organising Committee)	Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2017 - 2017	Participation Congress	II International Congress in Health Sciences Research Towards Innovation and Entrepreneurship: Trends in Biotechnology for Biomedical Applications Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2017 - 2017	Participation Meeting	Encontro com a Ciência e Tecnologia
2015 - 2015	Participation Meeting	VIII Jornadas sobre Tecnologia e Saúde Instituto Politécnico da Guarda, Portugal
2014 - 2014	Participation Meeting	II Encontro Nacional de Estudantes de Química (II ENEQUI) Universidade da Beira Interior, Portugal
2014 - 2014	Participation Meeting	Encontro Bienal das Divisões Técnicas da Sociedade Portuguesa de Materiais (SPM) Universidade da Beira Interior, Portugal
2014 - 2014	Participation Symposium	IX Anual CICS Symposium Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2014 - 2014	Participation Other	Semana da Ciência Universidade da Beira Interior, Portugal
2013 - 2013	Participation Symposium	VIII Anual CICS Symposium Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013 - 2013	Participation Conference	I Ciclo de Conferências - Biomédicas à Tarde Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013 - 2013	Participation Meeting	VI Jornadas Nacionais sobre Tecnologia e Saúde Instituto Politécnico da Guarda, Portugal
2012 - 2012	Participation Meeting	Fórum Biotecnologia Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2012 - 2012	Participation Symposium	II Simpósio em Emprego e Oportunidades em Ciências Biomédicas Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2011 - 2011	Participation Meeting	II Jornadas Nacionais de Ciências Biomédicas Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2011 - 2011	Participation Symposium	I Simpósio em Emprego e Oportunidades em Ciências Biomédicas Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2019	Nanopartículas inorgânicas para a terapia do cancro. (Thesis) Arguer	Catarina Coelho (Other) Universidade da Beira Interior, Portugal
2018	Biomateriais antibacterianos para o tratamento de lesões da pele. (Thesis) Arguer	Mariana Graça (Other) Universidade da Beira Interior, Portugal
2018	Biomateriais antibacterianos para o tratamento de lesões da pele. (Thesis) Arguer	Carolina Batista (Other) Universidade da Beira Interior, Portugal
2018	Funcionalização de nanomateriais à base de óxido de grafeno para entrega de fármacos e terapia fototérmica do cancro. (Thesis) Arguer	Alexandre Santos (Other) Universidade da Beira Interior, Portugal
2018	Nanopartículas na hipertermia de fluídos magnéticos para o tratamento do cancro. (Thesis) Arguer	Catarina Coelho (Other) Universidade da Beira Interior, Portugal
2017	Desenvolvimento de sistemas de entrega de fármacos inovadores. (Thesis) Arguer	Cláudia Silva (Other) Universidade da Beira Interior, Portugal
2017	Microagulhas poliméricas para entrega de fármacos a células cancerígenas. (Thesis) Arguer	Inês Deus (Other) Universidade da Beira Interior, Portugal
2015	Técnicas de produção de moldes na medicina regenerativa. (Thesis) Arguer	Patrícia Brito (Other) Universidade da Beira Interior, Portugal
2015	Hidrogéis para entrega de células na Engenharia de Tecidos. (Thesis) Arguer	Liliana Fernandes (Other) Universidade da Beira Interior, Portugal
2014	O papel dos hidrogéis no tratamento de úlceras de pressão. (Thesis) Arguer	Joana Fernandes (Other) Universidade da Beira Interior, Portugal
2014	Desenvolvimento de scaffolds à base de nanofibras para o tratamento de doenças ósseas. (Thesis) Arguer	Daniela Figueira (Other) Universidade da Beira Interior, Portugal
2014	Nanopartículas multifuncionais como veículos de entrega de moléculas bioativas com atividade anti-cancerígena. (Thesis) Arguer	Luís Xavier (Other) Universidade da Beira Interior, Portugal

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2018 - 2019	Bioquímica II (total 24 hours)	Biotecnologia (Licenciatura)	Universidade da Beira Interior, Portugal
2018 - 2019	Biomateriais (total 2 hours)	Bioquímica (Licenciatura)	Universidade da Beira Interior, Portugal
2018 - 2019	Biomateriais (total 2 hours)	Bioengenharia (Licenciatura)	Universidade da Beira Interior, Portugal
2018 - 2019	Biomateriais (total 2 hours)	Ciências Biomédicas (Licenciatura)	Universidade da Beira Interior, Portugal
2018 - 2019	Biomateriais (total 2 hours)	Biotecnologia (Licenciatura)	Universidade da Beira Interior, Portugal
2018 - 2019	Engenharia de Tecidos (total 4 hours)	Bioquímica	Universidade da Beira Interior, Portugal
2018 - 2019	Engenharia de Tecidos (total 4 hours)	Bioengenharia (Mestrado)	Universidade da Beira Interior, Portugal
2018 - 2019	Engenharia de Tecidos (total 4 hours)	Ciências Biomédicas (Mestrado)	Universidade da Beira Interior, Portugal
2018 - 2019	Engenharia de Tecidos (total 6 hours)	Biotecnologia (Mestrado)	Universidade da Beira Interior, Portugal
2017 - 2018	Bioquímica II (total 16 hours)	Ciências Biomédicas (Licenciatura)	Universidade da Beira Interior, Portugal
2017 - 2018	Bioquímica II (total 24 hours)	Ciências Básicas Farmacêuticas (Licenciatura)	Universidade da Beira Interior, Portugal
2017 - 2018	Biomateriais (total 2 hours)	Bioquímica (Licenciatura)	Universidade da Beira Interior, Portugal
2017 - 2018	Biomateriais (total 2 hours)	Ciências Biomédicas (Licenciatura)	Universidade da Beira Interior, Portugal
2017 - 2018	Engenharia de Tecidos (total 6 hours)	Biotecnologia (Mestrado)	Universidade da Beira Interior, Portugal
2016 - 2017	Bioquímica II (total 26 hours)	Bioquímica (Licenciatura)	Universidade da Beira Interior, Portugal
2016 - 2017	Biomateriais (total 4 hours)	Bioquímica (Licenciatura)	Universidade da Beira Interior, Portugal
2016 - 2017	Biomateriais (total 4 hours)	Bioengenharia (Licenciatura)	Universidade da Beira Interior, Portugal
2016 - 2017	Biomateriais (total 8 hours)	Ciências Biomédicas (Licenciatura)	Universidade da Beira Interior, Portugal
2016 - 2017	Biomateriais (total 4 hours)	Biotecnologia (Licenciatura)	Universidade da Beira Interior, Portugal
2016 - 2017	Engenharia de Tecidos (total 4 hours)	Bioquímica (Mestrado)	Universidade da Beira Interior, Portugal
2016 - 2017	Engenharia de Tecidos (total 4 hours)	Bioengenharia (Mestrado)	Universidade da Beira Interior, Portugal
2016 - 2017	Engenharia de Tecidos (total 4 hours)	Ciências Biomédicas (Mestrado)	Universidade da Beira Interior, Portugal
2016 - 2017	Engenharia de Tecidos (total 4 hours)	Biotecnologia (Mestrado)	Universidade da Beira Interior, Portugal
2015 - 2016	Bioquímica II (total 28 hours)	Bioquímica (Licenciatura)	Universidade da Beira Interior, Portugal
2015 - 2016	Bioquímica II (total 30 hours)	Ciências Biomédicas (Licenciatura)	Universidade da Beira Interior, Portugal
2015 - 2016	Biomateriais (total 2 hours)	Bioquímica (Licenciatura)	Universidade da Beira Interior, Portugal
2015 - 2016	Biomateriais (total 2 hours)	Ciências Biomédicas (Licenciatura)	Universidade da Beira Interior, Portugal
2015 - 2016	Biomateriais (total 2 hours)	Biotecnologia (Licenciatura)	Universidade da Beira Interior, Portugal
2015 - 2016	Engenharia de Tecidos (total 4 hours)	Bioengenharia (Mestrado)	Universidade da Beira Interior, Portugal
2015 - 2016	Engenharia de Tecidos (total 2 hours)	Ciências Biomédicas (Mestrado)	Universidade da Beira Interior, Portugal
2015 - 2016	Engenharia de Tecidos (total 2 hours)	Biotecnologia (Mestrado)	Universidade da Beira Interior, Portugal

Interview (newspaper / magazine)

	Activity description	Newspaper / Forum
2017/12/05	In order to mimic not only the 3D structure but also the cell-ECM interactions that occur in tumors, researchers are currently using ECM components, like hyaluronic acid (HA). This polymer is one of the main constituents of tumor ECM, it has an essential role in cancer progression and it avoids cell adhesion in vitro. In a recent work from my research group, it was optimized, for the first time, the coating of surfaces with HA that was used for the production of reproducible heterotypic breast cancer spheroids.	Science Trends
2017/03/09	Os materiais à base de óxido de grafeno têm sido utilizados como transportadores de fármacos na terapia do cancro. Estes materiais têm a capacidade de absorver luz e emitir posteriormente a energia sob a forma de calor, o que lhes permite induzir danos nas células cancerígenas – uma propriedade essencial para a sua aplicação em terapia fototérmica.	Associação Portuguesa de Investigação em Cancro (ASPIC)
2015/03/11	Elisabete Costa está a criar uma forma de simulação de tumores para facilitar e reduzir os custos na descoberta de novos medicamentos contra vários tipos de tumores.	Jornal Online da UBI, da Região e do Resto (Urbi et Orbi)
2013/09/09	In the present study we used different ratios of breast cancer cells to fibroblasts, in order to better mimic in vitro the breast tumor microenvironment heterogeneity. The confocal microscopy and flow cytometry results demonstrate that different concentrations of fibroblasts in co-culture could influence the cellular uptake of the polymeric nanoparticles studied.	Associação Portuguesa de Investigação em Cancro (ASPIC)

Interview (tv / radio show)

	Program	Topic
2015/03/06 - Current	Jornal da Tarde	Células cancerígenas 3D

Distinctions

Award

2017	Best poster award: Functionalization of graphene oxide for anticancer applications, V Ciclo de Conferências da Faculdade de Ciências. Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2015	Best poster award: Assembly of breast cancer spheroids, X Annual CICS Symposium. Instituto Politécnico da Guarda, Portugal
2015	Best poster award: Optimization of Liquid Overlay Technique (LOT) to produce 3D breast and cervical co-culture models, VIII Jornadas sobre Tecnologia e Saúde. Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013	Best poster award: Mimicking breast cancer microenvironment with in vitro co-culture models, VI Jornadas sobre Tecnologia e Saúde. Instituto Politécnico da Guarda, Portugal

Other distinction

2021	World's TOP 2% Scientist (DOI: 10.17632/btchxktzyw.3).