Joana Crisóstomo is deeply committed to uncovering the brain mechanisms underlying body energy homeostasis and its implications in metabolic diseases, such as obesity and diabetes. Joana has a BSc in Biology and a MSc in Cellular and Molecular Biology. She obtained a PhD in Health Sciences at the Faculty of Medicine of the University of Coimbra in 2017, supported by an Individual Doctoral Fellowship from Fundação para a Ciência e a Tecnologia. Currently, she is a postdoctoral researcher at the Champalimaud Foundation, working on a very challenging ERC-funded project to investigate feeding behaviour in humans. Her academic training and research experience both in basic and clinical research have provided her with a multidisciplinary background. She has described disease mechanisms, evaluated nutritional and pharmacological treatments, developed bioengineered treatments, and explored biomarkers with diagnostic and prognostic value in clinical populations. Recently she embraced the field of neuroscience and neuroimaging. In the field of diabetes, she reported MRI studies showing correlations of metabolic control with alterations of brain morphometric measures and she is investigating the neural correlates of diabetes-related complications with functional MRI (fMRI). She is also using fMRI and transcranial direct current stimulation (tDCS) in a european project investigating the effects of neurostimulation in the modulation of brain functional connectivity in neurodevelopmental disorders. The interest in brain structure and function and their crosstalk with gastrointestinal players in obesity is also being explored in a project in which she is leveraging both task-based fMRI and positron emission tomography (PET) to investigate the neural correlates of dysfunctional feeding behaviour and underlying neurotransmitter imbalance in brain reward pathways in this population, and the effect of bariatric surgery on this context. Currently, she is also using PET to characterize dopamine brain signalling of post-ingestive caloric reward. Joana is also very interested in the translation of knowledge from basic research to clinical application. Both outside and inside academia, she has participated in national and european clinical studies and trials, namely investigator-initiated trials. Joana published 23 articles in peer-reviewed journals, 3 book chapters and received 7 scientific awards. She has a total of 1024 citations and an H-index of 13. She has participated in several scientific events’ organization and science dissemination activities, both to academic and general audiences. She is also an Invited Assistant Professor at the University of Coimbra. Moreover, she is co-supervising 1 PhD candidate, co-supervised 2 MSc dissertations, and was jury in 1 MSc dissertation and 1 BSc dissertation.