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Identificação

Identificação pessoal

Nome completo
Carlos Alberto Mateus Afonso

Identificadores de autor

Ciência ID
6319-2E4C-5BE1
ORCID iD
0000-0002-7284-5948

Websites

Formação
Grau Classificação
2008
Concluído
 Química (Título de Agregado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"." (TESE/DISSERTAÇÃO)
 .
1990
Concluído
 Química (Doutoramento)
Universidade Nova de Lisboa, Portugal
 ....
1984
Concluído
 Química Industrial (Licenciatura)
Universidade de Coimbra, Portugal
 ....
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2010/02/01 - Atual Professor Catedrático (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal
2004/03/01 - 2010/07/31 Professor Associado (Docente Universitário) Universidade de Lisboa Instituto Superior Técnico, Portugal
1995 - 2004 Professor Auxiliar (Docente Universitário) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
1990 - 1995 Professor Auxiliar (Docente Universitário) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
1987 - 1990 Assistente (Docente Universitário) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
1985 - 1987 Assistente Estagiário (Docente Universitário) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
1998/03/01 - 1998/08/31 Visitor (sabbatical leave) University of Toronto Department of Chemistry, Canadá
1997/09/01 - 1998/02/28 Visitor (sabbatical leave) University of Bath Department of Chemistry, Reino Unido
1990/09/01 - 1991/08/31 Post-doc Imperial College London, Reino Unido
Produções

Publicações

Artigo em conferência
  1. Mariana Crespo Monteiro; Carlos A. M. Afonso; Filipa Siopa. "Pd-Catalyzed Cycloaddition of Bicyclic Aziridine with Isocyanates". 2022.
    10.3390/ECMC2022-13424
  2. Neves, L.A.; Afonso, C.A.M.; Coelhoso, L.M.; Crespo, J.G.. "CO2 capture by enzymatic bioconversion in a membrane contactor with task specific ionic liquids". 2012.
    10.1016/j.proeng.2012.08.485
  3. Daniel, C.I.; Afonso, C.A.; Chavez, F.V.; Sebastiao, P.J.; Portugal, C.A.; Crespo, J.G.. "Study of the behavior of magnetic ionic liquids supported membranes for selective Transport". 2012.
    10.1016/j.proeng.2012.08.350
  4. Kulkami, P.S.; Neves, L.; Coelhoso, I.; Afonso, C.A.M.; Crespo, J.G.. "Supported ionic liquid membranes for removal of persistent organic pollutants (dioxins)". 2012.
    10.1016/j.proeng.2012.08.337
Artigo em revista
  1. Mário R. C. Soromenho; Carlos A. M. Afonso; José M. S. S. Esperança. "Diarylethene-Based Ionic Liquids: Synthesis and Photo-Driven Solution Properties". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24043533.
    10.3390/ijms24043533
  2. Lídia A. S. Cavaca; Jaime A. S. Coelho; Susana D. Lucas; Rui M. S. Loureiro; Rafael F. A. Gomes; Carlos A. M. Afonso. "Upgrading furanic platforms to a-enaminones: tunable continuous flow hydrogenation of bio-based cyclopentenones". Reaction Chemistry & Engineering (2023): https://doi.org/10.1039/D2RE00292B.
    10.1039/D2RE00292B
  3. João R. Vale; Rafael F. Gomes; Carlos A. M. Afonso; Nuno R. Candeias. "Functionalized Cyclopentenes via the Formal [4+1] Cycloaddition of Photogenerated Siloxycarbenes from Acyl Silanes". The Journal of Organic Chemistry (2022): https://doi.org/10.1021/acs.joc.2c00591.
    10.1021/acs.joc.2c00591
  4. Andreia A. Rosatella; Carlos A. M. Afonso. "Stereoselective Synthesis and Isolation of (±)-trans,trans-Cyclohexane-1,2,4,5-tetraol". AppliedChem 2 3 (2022): 142-148. https://doi.org/10.3390/appliedchem2030010.
    10.3390/appliedchem2030010
  5. Teresa Esteves; Flávio A. Ferreira; Ana Teresa Mota; Ángel Sánchez-González; Adrià Gil; Késsia H. S. Andrade; Carlos A. M. Afonso; Frederico Castelo Ferreira. "Greener Strategy for Lupanine Purification from Lupin Bean Wastewaters Using a Molecularly Imprinted Polymer". ACS Applied Materials & Interfaces (2022): https://doi.org/10.1021/acsami.2c02053.
    10.1021/acsami.2c02053
  6. Andreia A. Rosatella; Carlos A. M. Afonso. "One-Pot Transformation of Salicylaldehydes to Spiroepoxydienones via the Adler–Becker Reaction in a Continuous Flow". ACS Omega 7 14 (2022): 11570-11577. https://doi.org/10.1021/acsomega.1c05559.
    10.1021/acsomega.1c05559
  7. Lídia A. S. Cavaca; Rafael F. A. Gomes; Carlos A. M. Afonso. "Preparation of Thioaminals in Water". Molecules (2022): https://doi.org/10.3390/molecules27051673.
    10.3390/molecules27051673
  8. Rafael F. A. Gomes; Joao M. J. M. Ravasco; Késsia H. S. Andrade; Jaime A. S. Coelho; Rui Moreira; Rafael Oliveira; Fátima Nogueira; Carlos A. M. Afonso. "Tandem Thio-Michael Addition/Remote Lactone Activation of 5-Hydroxymethylfurfural-Derived d-Lactone-Fused Cyclopentenones". ChemSusChem (2022): https://doi.org/10.1002/cssc.202102204.
    10.1002/cssc.202102204
  9. Marina Ciriani; Rudi Oliveira; Carlos A. M. Afonso. "Semi-continuous and continuous processes for enantiomeric separation". Green Chemistry (2022): https://doi.org/10.1039/D1GC03668H.
    10.1039/D1GC03668H
  10. Rafael F. A. Gomes; Lídia A. S. Cavaca; João M. Gonçalves; Ruben Ramos; Andreia F. Peixoto; Blanca I. Arias-Serrano; Carlos A. M. Afonso. "Silica-Supported Copper for the Preparation of trans-4,5-Diamino-Cyclopent-2-Enones under Continuous Flow Conditions". ACS Sustainable Chemistry & Engineering (2021): https://doi.org/10.1021/acssuschemeng.1c00884.
    10.1021/acssuschemeng.1c00884
  11. Sara R. Oliveira; Pedro A. Dionísio; Maria M. Gaspar; Maria B. T. Ferreira; Catarina A. B. Rodrigues; Rita G. Pereira; Mónica S. Estevão; et al. "Discovery of a Necroptosis Inhibitor Improving Dopaminergic Neuronal Loss after MPTP Exposure in Mice". International Journal of Molecular Sciences (2021): https://doi.org/10.3390/ijms22105289.
    10.3390/ijms22105289
  12. Milene Fortunato; Filipa Siopa; Carlos Afonso. "(1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol". Molbank 2021 2 (2021): M1199-M1199. https://doi.org/10.3390/M1199.
    10.3390/M1199
  13. Rui Cordeiro; Maria J. Beira; Carlos Cruz; João L. Figueirinhas; Marta C. Corvo; Pedro L. Almeida; Andreia A. Rosatella; et al. "Tuning the 1H NMR Paramagnetic Relaxation Enhancement and Local Order of [Aliquat]+-Based Systems Mixed with DMSO". International Journal of Molecular Sciences 22 2 (2021): 706-706. https://doi.org/10.3390/ijms22020706.
    10.3390/ijms22020706
  14. Esteves, Teresa; Mota, Ana Teresa; Barbeitos, Catarina; Andrade, Késsia; Afonso, Carlos A.M.; Ferreira, Frederico Castelo. "A study on lupin beans process wastewater nanofiltration treatment and lupanine recovery". Journal of Cleaner Production 277 (2020): 123349. http://dx.doi.org/10.1016/j.jclepro.2020.123349.
    Publicado • 10.1016/j.jclepro.2020.123349
  15. Oliveira, João A.C.; Kiala, Gredy; Siopa, Filipa; Bernard, Aurélie; Gontard, Geoffrey; Oble, Julie; Afonso, Carlos A.M.; Poli, Giovanni. "Palladium-catalyzed allylic substitution between C-based nucleophiles and 6-azabicyclo[3.1.0]-hex-3-en-2-oxy derivatives: A new selectivity paradigm". Tetrahedron 76 51 (2020): 131182. http://dx.doi.org/10.1016/j.tet.2020.131182.
    Publicado • 10.1016/j.tet.2020.131182
  16. Anisha Viswanathan; Aliyu Musa; Akshaya Murugesan; João R. Vale; Carlos A. M. Afonso; Saravanan Konda Mani; Olli Yli-Harja; Nuno R. Candeias; Meenakshisundaram Kandhavelu. "Erratum: Viswanathan, A., et al. Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect (Running Title: Cancer Cells Death Signalling Activation). Cells 2019, 8, 1624". Cells 9 12 (2020): 2631-2631. https://doi.org/10.3390/cells9122631.
    10.3390/cells9122631
  17. Celso Martins; Diego O. Hartmann; Adélia Varela; Jaime A. S. Coelho; Pedro Lamosa; Carlos A. M. Afonso; Cristina Silva Pereira. "Securing a furan-based biorefinery: disclosing the genetic basis of the degradation of hydroxymethylfurfural and its derivatives in the model fungus Aspergillus nidulans". Microbial Biotechnology 13 6 (2020): 1983-1996. https://doi.org/10.1111/1751-7915.13649.
    10.1111/1751-7915.13649
  18. Garcia, Catarina; Isca, Vera M. S.; Pereira, Filipe; Monteiro, Carlos M.; Ntungwe, Epole; Sousa, Francisco; Dinic, Jelena; et al. "Royleanone Derivatives From Plectranthus spp. as a Novel Class of P-Glycoprotein Inhibitors". Frontiers in Pharmacology 11 (2020): http://dx.doi.org/10.3389/fphar.2020.557789.
    Publicado • 10.3389/fphar.2020.557789
  19. Martins, C.F.; Neves, L.A.; Chagas, R.; Ferreira, L.M.; Afonso, C.A.M.; Crespo, J.G.; Coelhoso, I.M.. "CO2 removal from anaesthesia circuits using gas-ionic liquid membrane contactors". Separation and Purification Technology 250 (2020): 116983. http://dx.doi.org/10.1016/j.seppur.2020.116983.
    Publicado • 10.1016/j.seppur.2020.116983
  20. Ferreira, Inês C.; Araújo, Diana; Voisin, Pierre; Alves, Vítor D.; Rosatella, Andreia A.; Afonso, Carlos A.M.; Freitas, Filomena; Neves, Luísa A.. "Chitin-glucan complex – Based biopolymeric structures using biocompatible ionic liquids". Carbohydrate Polymers 247 (2020): 116679. http://dx.doi.org/10.1016/j.carbpol.2020.116679.
    Publicado • 10.1016/j.carbpol.2020.116679
  21. Barbosa, Sandro L.; de Freitas, Milton S.; dos Santos, Wallans T. P.; Nelson, David Lee; de Freitas Marques, Maria Betânia; Klein, Stanlei I.; Clososki, Giuliano C.; et al. "Preparation of activated charcoal from Acrocomia aculeata for purification of pretreated crude glycerol". Biomass Conversion and Biorefinery (2020): http://dx.doi.org/10.1007/s13399-020-00745-7.
    Publicado • 10.1007/s13399-020-00745-7
  22. Vera M. S. Isca; Milan Sencanski; Nenad Filipovic; Daniel J. V. A. Dos Santos; Ana Cipak Gašparovic; Lucília Saraíva; Carlos A. M. Afonso; Patrícia Rijo; Alfonso T. García-Sosa. "Activity to Breast Cancer Cell Lines of Different Malignancy and Predicted Interaction with Protein Kinase C Isoforms of Royleanones". International Journal of Molecular Sciences (2020): https://doi.org/10.3390/ijms21103671.
    10.3390/ijms21103671
  23. Parmaki, Stella; Tsipa, Argyro; Vasquez, Marlen I.; Gonçalves, João M. J.; Hadjiadamou, Ioanna; Ferreira, Frederico C.; Afonso, Carlos A. M.; Drouza, Chrysoulla; Koutinas, Michalis. "Resolution of alkaloid racemate: a novel microbial approach for the production of enantiopure lupanine via industrial wastewater valorization". Microbial Cell Factories 19 1 (2020): http://dx.doi.org/10.1186/s12934-020-01324-1.
    Publicado • 10.1186/s12934-020-01324-1
  24. Isca, Vera M. S.; Ferreira, Ricardo J.; Garcia, Catarina; Monteiro, Carlos M.; Dinic, Jelena; Holmstedt, Suvi; André, Vânia; et al. "Molecular Docking Studies of Royleanone Diterpenoids from Plectranthus spp. as P-Glycoprotein Inhibitors". ACS Medicinal Chemistry Letters 11 5 (2020): 839-845. http://dx.doi.org/10.1021/acsmedchemlett.9b00642.
    Publicado • 10.1021/acsmedchemlett.9b00642
  25. Juliana G. Pereira; João P. M. António; Ricardo Mendonça; Rafael F. A. Gomes; Carlos A. M. Afonso. "Rediscovering aminal chemistry: copper(ii) catalysed formation under mild conditions". Green Chemistry (2020): https://doi.org/10.1039/D0GC01977A.
    10.1039/D0GC01977A
  26. Anisha Viswanathan; Aliyu Musa; Akshaya Murugesan; João R. Vale; Carlos A. M. Afonso; Saravanan Konda Mani; Olli Yli-Harja; Nuno R. Candeias; Meenakshisundaram Kandhavelu. "Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect (Running Title: Cancer Cells Death Signalling Activation)". Cells (2019): https://doi.org/10.3390/cells8121624.
    10.3390/cells8121624
  27. Oscar H. Pardo Cuervo; Svilen P. Simeonov; Andreia F. Peixoto; Margarita D. Popova; Hristina I. Lazarova; Gustavo P. Romanelli; José J. Martínez; Cristina Freire; Carlos A. M. Afonso. "Efficient Continuous Production of the Biofuel Additive 5-( t- Butoxymethyl) Furfural from 5-Hydroxymethylfurfural". Energy Technology 7 11 (2019): 1900780-1900780. https://doi.org/10.1002/ente.201900780.
    10.1002/ente.201900780
  28. João M. J. M. Ravasco; Carlos M. Monteiro; Filipa Siopa; Alexandre F. Trindade; Julie Oble; Giovanni Poli; Svilen P. Simeonov; Carlos A. M. Afonso. "Creating Diversity from Biomass: A Tandem Bio/Metal-Catalysis towards Chemoselective Synthesis of Densely Substituted Furans". ChemSusChem (2019): https://doi.org/10.1002/cssc.201902051.
    10.1002/cssc.201902051
  29. Flávio Alves Ferreira; Teresa Esteves; Marta P. Carrasco; João Bandarra; Carlos A. M. Afonso; Frederico Castelo Ferreira. "Polybenzimidazole for Active Pharmaceutical Ingredient Purification: The Mometasone Furoate Case Study". Industrial & Engineering Chemistry Research (2019): https://doi.org/10.1021/acs.iecr.9b01285.
    10.1021/acs.iecr.9b01285
  30. Rafael F. A. Gomes; Jaime A. S. Coelho; Carlos A. M. Afonso. "Direct Conversion of Activated 5-Hydroxymethylfurfural into d-Lactone-Fused Cyclopentenones". ChemSusChem (2019): https://doi.org/10.1002/cssc.201802537.
    10.1002/cssc.201802537
  31. Ravasco, J.M.J.M.; Coelho, J.A.S.; Trindade, A.F.; Afonso, C.A.M.. "Synthesis and reactivity/stability study of double-functionalizable strained trans-cyclooctenes for tetrazine bioorthogonal reactions". Pure and Applied Chemistry (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85066324606&partnerID=MN8TOARS.
    10.1515/pac-2019-0201
  32. Vale, J.R.; Valkonen, A.; Afonso, C.A.M.; Candeias, N.R.. "Synthesis of silacyclopent-2-en-4-ols: Via intramolecular [2 + 2] photocycloaddition of benzoyl(allyl)silanes". Organic Chemistry Frontiers 6 22 (2019): 3793-3798. http://www.scopus.com/inward/record.url?eid=2-s2.0-85074670207&partnerID=MN8TOARS.
    10.1039/c9qo01028a
  33. João R. Vale; Arto Valkonen; Carlos A. M. Afonso; Nuno R. Candeias. "Synthesis of silacyclopent-2-en-4-ols via intramolecular [2 + 2] photocycloaddition of benzoyl(allyl)silanes". Organic Chemistry Frontiers (2019): https://doi.org/10.1039/C9QO01028A.
    10.1039/C9QO01028A
  34. Filipa Siopa; Raquel F. M. Frade; Ana Diniz; Joana M. Andrade; Marisa Nicolai; Ana Meirinhos; Susana D. Lucas; et al. "Acetylcholinesterase Choline-Based Ionic Liquid Inhibitors: In Vitro and in Silico Molecular Docking Studies". ACS Omega (2018): https://doi.org/10.1021/acsomega.8b02347.
    10.1021/acsomega.8b02347
  35. Nikolai Stanev; João C. M. Bordado; Carlos A. M. Afonso; Svilen P. Simeonov. "Solvent-Free Catalytic Self-Etherification of 5-Hydroxymethyl Furfural". ChemCatChem (2018): https://doi.org/10.1002/cctc.201801560.
    10.1002/cctc.201801560
  36. Filipa Siopa; Valérie-Anne Ramis Cladera; Carlos Alberto Mateus Afonso; Julie Oble; Giovanni Poli. "Ruthenium-Catalyzed C-H Arylation and Alkenylation of Furfural Imines with Boronates". European Journal of Organic Chemistry 2018 44 (2018): 6101-6106. https://doi.org/10.1002/ejoc.201800767.
    10.1002/ejoc.201800767
  37. Teresa Esteves; Ana I. Vicente; Flávio A. Ferreira; Carlos A.M. Afonso; Frederico Castelo Ferreira. "Mimicking DNA alkylation: Removing genotoxin impurities from API streams with a solvent stable polybenzimidazole-adenine polymer". Reactive and Functional Polymers 131 (2018): 258-265. https://doi.org/10.1016/j.reactfunctpolym.2018.07.019.
    10.1016/j.reactfunctpolym.2018.07.019
  38. Rafael F. A. Gomes; Nuno R. Esteves; Jaime A. S. Coelho; Carlos A. M. Afonso. "Copper(II) Triflate As a Reusable Catalyst for the Synthesis of trans-4,5-Diamino-cyclopent-2-enones in Water". The Journal of Organic Chemistry 83 14 (2018): 7509-7513. https://doi.org/10.1021/acs.joc.7b02931.
    10.1021/acs.joc.7b02931
  39. Mário R.C. Soromenho; Filipa Siopa; Carlos A.M. Afonso; José M.S.S. Esperança. "Enhanced photoconversion of 1,2-bis(2-methyl-1-benzothiophene-3-yl)perfluorocyclopentene in ionic liquid solutions". Journal of Photochemistry and Photobiology A: Chemistry 358 (2018): 44-50. https://doi.org/10.1016/j.jphotochem.2018.03.002.
    10.1016/j.jphotochem.2018.03.002
  40. Filipa Siopa; João P. M. António; Carlos A. M. Afonso. "Flow-Assisted Synthesis of Bicyclic Aziridines via Photochemical Transformation of Pyridinium Salts". Organic Process Research & Development 22 4 (2018): 551-556. https://doi.org/10.1021/acs.oprd.8b00036.
    10.1021/acs.oprd.8b00036
  41. Catarina A. B. Rodrigues; Iris Neto; Patricia Rijo; Carlos A. M. Afonso. "Synthesizing a Berberine Derivative and Evaluating Antimicrobial Activity To Reinforce with Students the Potential Significance of Small Chemical Structure Changes for Biological Systems". Journal of Chemical Education 95 3 (2018): 492-495. https://doi.org/10.1021/acs.jchemed.7b00458.
    10.1021/acs.jchemed.7b00458
  42. João R. Vale; Tatu Rimpiläinen; Elina Sievänen; Kari Rissanen; Carlos A. M. Afonso; Nuno R. Candeias. "Pot-Economy Autooxidative Condensation of 2-Aryl-2-lithio-1,3-dithianes". The Journal of Organic Chemistry 83 4 (2018): 1948-1958. https://doi.org/10.1021/acs.joc.7b02896.
    10.1021/acs.joc.7b02896
  43. Subbiah Sowmiah; José M. S. S. Esperança; Luís P. N. Rebelo; Carlos A. M. Afonso. "Pyridinium salts: from synthesis to reactivity and applications". Organic Chemistry Frontiers (2018): https://doi.org/10.1039/C7QO00836H.
    10.1039/C7QO00836H
  44. Parmaki, S.; Vyrides, I.; Vasquez, M.I.; Hartman, V.; Zacharia, I.; Hadjiadamou, I.; Barbeitos, C.B.M.; et al. "Bioconversion of alkaloids to high-value chemicals: Comparative analysis of newly isolated lupanine degrading strains". Chemosphere 193 (2018): 50-59. http://www.scopus.com/inward/record.url?eid=2-s2.0-85033363305&partnerID=MN8TOARS.
    10.1016/j.chemosphere.2017.10.165
  45. Sowmiah, S.; Esperança, J.M.S.S.; Rebelo, L.P.N.; Afonso, C.A.M.. "Pyridinium salts: From synthesis to reactivity and applications". Organic Chemistry Frontiers 5 3 (2018): 453-493. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041374468&partnerID=MN8TOARS.
    10.1039/c7qo00836h
  46. de França, A.D.S.; Silva, M.V.M.; Neves, R.V.; de Souza, S.P.; Leão, R.A.C.; Monteiro, C.M.; Rocha, Â.; Afonso, C.A.M.; de Souza, R.O.M.A.. "Studies on the dynamic resolution of Crizotinib intermediate". Bioorganic and Medicinal Chemistry 26 7 (2018): 1333-1337. http://www.scopus.com/inward/record.url?eid=2-s2.0-85027273548&partnerID=MN8TOARS.
    10.1016/j.bmc.2017.07.024
  47. Garcia, C.; Silva, C.O.; Monteiro, C.M.; Nicolai, M.; Viana, A.; Andrade, J.M.; Barasoain, I.; et al. "Anticancer properties of the abietane diterpene 6, 7-dehydroroyleanone obtained by optimized extraction". Future Medicinal Chemistry 10 10 (2018): 1177-1189. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048107643&partnerID=MN8TOARS.
    10.4155/fmc-2017-0239
  48. Maria Beira; Carla I. Daniel; Pedro L. Almeida; Marta C. Corvo; Andreia A. Rosatella; Carlos A. M. Afonso; Pedro J. Sebastião. "1H NMR Relaxometry and Diffusometry Study of Magnetic and Nonmagnetic Ionic Liquid-Based Solutions: Cosolvent and Temperature Effects". The Journal of Physical Chemistry B 121 51 (2017): 11472-11484. https://doi.org/10.1021/acs.jpcb.7b07929.
    10.1021/acs.jpcb.7b07929
  49. Restolho, J.; Barroso, M.; Saramago, B.; Dias, M.; Afonso, C.A.M.. "Response to the letter to the editor Reply to Restolho et al. “Contactless decontamination of hair samples: cannabinoids” by Moosmann and Auwärter". Drug Testing and Analysis 9 2 (2017): 290-292. http://www.scopus.com/inward/record.url?eid=2-s2.0-85010411121&partnerID=MN8TOARS.
    10.1002/dta.2150
  50. Zupancic, E.; Curato, C.; Paisana, M.; Rodrigues, C.; Porat, Z.; Viana, A.S.; Afonso, C.A.M.; et al. "Rational design of nanoparticles towards targeting antigen-presenting cells and improved T cell priming". Journal of Controlled Release 258 (2017): 182-195. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019758479&partnerID=MN8TOARS.
    10.1016/j.jconrel.2017.05.014
  51. Vicente, A.I.; Esteves, T.; Afonso, C.A.M.; Ferreira, F.C.. "Solvent compatible polymer functionalization with adenine, a DNA base, for API degenotoxification: Preparation and characterization". Separation and Purification Technology 179 (2017): 438-448. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013270531&partnerID=MN8TOARS.
    10.1016/j.seppur.2017.02.011
  52. Sintra, T.E.; Nasirpour, M.; Siopa, F.; Rosatella, A.A.; Gonçalves, F.; Coutinho, J.A.P.; Afonso, C.A.M.; Ventura, S.P.M.. "Ecotoxicological evaluation of magnetic ionic liquids". Ecotoxicology and Environmental Safety 143 (2017): 315-321. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019664958&partnerID=MN8TOARS.
    10.1016/j.ecoenv.2017.05.034
  53. Restolho, J.; Barroso, M.; Saramago, B.; Dias, M.; Afonso, C.A.M.. "Contactless decontamination of hair samples: cannabinoids". Drug Testing and Analysis 9 2 (2017): 282-288. http://www.scopus.com/inward/record.url?eid=2-s2.0-84963830541&partnerID=MN8TOARS.
    10.1002/dta.1958
  54. Scapin, E.; Frizzo, C.P.; Rodrigues, L.V.; Zimmer, G.C.; Vaucher, R.A.; Sagrillo, M.R.; Giongo, J.L.; et al. "Synthesis, antimicrobial activity and cytotoxic investigation of novel trifluoromethylated tetrazolo[1,5-a]pyrimidines". Medicinal Chemistry Research 26 3 (2017): 640-649. http://www.scopus.com/inward/record.url?eid=2-s2.0-85009830284&partnerID=MN8TOARS.
    10.1007/s00044-017-1783-3
  55. Peixoto, D.; Figueiredo, M.; Gawande, M.B.; Corvo, M.C.; Vanhoenacker, G.; Afonso, C.A.M.; Ferreira, L.M.; Branco, P.S.. "Developments in the Reactivity of 2-Methylimidazolium Salts". Journal of Organic Chemistry 82 12 (2017): 6232-6241. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020920835&partnerID=MN8TOARS.
    10.1021/acs.joc.7b00807
  56. Ravasco, J.M.J.M.; Coelho, J.A.S.; Simeonov, S.P.; Afonso, C.A.M.. "Bifunctional Cr3+modified ion exchange resins as efficient reusable catalysts for the production and isolation of 5-hydroxymethylfurfural from glucose". RSC Advances 7 13 (2017): 7555-7559. http://www.scopus.com/inward/record.url?eid=2-s2.0-85010657868&partnerID=MN8TOARS.
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  231. Sousa, H.A.; Afonso, C.A.M.; Mota, J.P.B.; Crespo, J.G.. "Enantioselective Hydrolysis of a meso-Diester Using Pig Liver Esterase in a Two-Phase Stirred Tank Reactor". Industrial and Engineering Chemistry Research 42 22 (2003): 5516-5525. http://www.scopus.com/inward/record.url?eid=2-s2.0-0142214699&partnerID=MN8TOARS.
  232. Gois, P.M.P.; Afonso, C.A.M.. "Dirhodium(II)-catalysed C-H insertion on a-diazo-a-phosphono-acetamides in an ionic liquid". Tetrahedron Letters 44 35 (2003): 6571-6573. http://www.scopus.com/inward/record.url?eid=2-s2.0-0043172281&partnerID=MN8TOARS.
    10.1016/S0040-4039(03)01700-3
  233. Lourenço, N.M.T.; Afonso, C.A.M.. "Ionic liquid as an efficient promoting medium for two-phase nucleophilic displacement reactions". Tetrahedron 59 6 (2003): 789-794. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037415491&partnerID=MN8TOARS.
    10.1016/S0040-4020(02)01621-6
  234. Moura Ramos, J.J.; Afonso, C.A.M.; Branco, L.C.. "Glass transition relaxation and fragility in two room temperature ionic liquids". Journal of Thermal Analysis and Calorimetry 71 2 (2003): 659-666. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037288757&partnerID=MN8TOARS.
  235. Afonso, C.A.M.; Santhakumar, V.; Lough, A.; Batey, R.A.. "An Expedient Synthesis of Cationic Rhodamine Fluorescent Probes Suitable for Conjugation to Amino Acids and Peptides". Synthesis 17 (2003): 2647-2654. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346753437&partnerID=MN8TOARS.
    10.1055/s-2003-42475
  236. Gois, P.M.P.; Afonso, C.A.M.. "Regio- and stereoselective dirhodium(II)-catalysed intramolecular C-H insertion reactions of a-diazo-a-(dialkoxyphosphoryl)acetamides and -acetates". European Journal of Organic Chemistry 19 (2003): 3798-3810. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141925976&partnerID=MN8TOARS.
    10.1002/ejoc.200300330
  237. Piçarra, S.; Relógio, P.; Afonso, C.A.M.; Martinho, J.M.G.; Farinha, J.P.S.. "Coil-Globule Transition of Poly(Dimethylacrylamide): Fluorescence and Light Scattering Study". Macromolecules 36 21 (2003): 8119-8129. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346047610&partnerID=MN8TOARS.
    10.1021/ma0345899
  238. Branco, L.C.; Crespo, J.G.; Afonso, C.A.M.. "Studies on the selective transport of organic compounds by using ionic liquids as novel supported liquid membranes". Chemistry - A European Journal 8 17 (2002): 3865-3871. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037009094&partnerID=MN8TOARS.
    10.1002/1521-3765(20020902)8:17<3865::AID-CHEM3865>3.0.CO;2-L
  239. Branco, L.C.; Rosa, J.N.; Moura Ramos, J.J.; Afonso, C.A.M.. "Preparation and characterization of new room temperature ionic liquids". Chemistry - A European Journal 8 16 (2002): 3671-3677. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037119330&partnerID=MN8TOARS.
    10.1002/1521-3765(20020816)8:16<3671::AID-CHEM3671>3.0.CO;2-9
  240. Afonso, C.A.M.; Farinha, J.P.S.. "Synthesis of 4-aryl-butylamine fluorescent probes". Journal of Chemical Research - Part S 11 (2002): 584-586. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036866045&partnerID=MN8TOARS.
  241. Branco, L.C.; Crespo, J.G.; Afonso, C.A.M.. "Highly selective transport of organic compounds by using supported liquid membranes based on ionic liquids". Angewandte Chemie - International Edition 41 15 (2002): 2771-2773. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037008606&partnerID=MN8TOARS.
    10.1002/1521-3773(20020802)41:15<2771::AID-ANIE2771>3.0.CO;2-U
  242. Branco, L.C.; Afonso, C.A.M.. "Catalytic asymmetric dihydroxylation of olefins using a recoverable and reusable OsO42- in ionic liquid [bmim][PF6]". Chemical Communications 8 24 (2002): 3036-3037. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036923083&partnerID=MN8TOARS.
    10.1039/b208631j
  243. Cabrita, E.J.; Afonso, C.A.M.; Gil De Oliveira Santos, A.. "Imide-amide rearrangement of cyclic phosphorimidates: A mechanistic study". Chemistry - A European Journal 7 7 (2001): 1455-1467. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035312949&partnerID=MN8TOARS.
    10.1002/1521-3765(20010401)7:7<1455::AID-CHEM1455>3.0.CO;2-U
  244. Branco, L.C.; Afonso, C.A.M.. "Ionic liquids as recyclable reaction media for the tetrahydropyranylation of alcohols". Tetrahedron 57 20 (2001): 4405-4410. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035858618&partnerID=MN8TOARS.
    10.1016/S0040-4020(01)00373-8
  245. Rosa, J.N.; Afonso, C.A.M.; Santos, A.G.. "Ionic liquids as a recyclable reaction medium for the Baylis-Hillman reaction". Tetrahedron 57 19 (2001): 4189-4193. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035821357&partnerID=MN8TOARS.
    10.1016/S0040-4020(01)00316-7
  246. Schäfer, T.; Rodrigues, C.M.; Afonso, C.A.M.; Crespo, J.G.. "Selective recovery of solutes from ionic liquids by pervaporation—a novel approach for purification and green processing". Chemical Communications 1 17 (2001): 1622-1623. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035823321&partnerID=MN8TOARS.
    10.1039/b104191f
  247. Gil Santos, A.; Candeias, S.X.; Afonso, C.A.M.; Jenkins, K.; Caddick, S.; Treweeke, N.R.; Pardoe, D.. "Rationalising diastereoselection in the dynamic kinetic resolution of a-haloacyl imidazolidinones: A theoretical approach". Tetrahedron 57 30 (2001): 6607-6614. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035939150&partnerID=MN8TOARS.
    10.1016/S0040-4020(01)00551-8
  248. Sousa, H.A.; Rodrigues, C.; Klein, E.; Afonso, C.A.M.; Crespo, J.G.. "Immobilisation of pig liver esterase in hollow fibre membranes". Enzyme and Microbial Technology 29 10 (2001): 625-634. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035814325&partnerID=MN8TOARS.
    10.1016/S0141-0229(01)00443-4
  249. Candeias, S.X.; Jenkins, K.; Ribeiro, A.S.C.; Afonso, C.A.M.; Caddick, S.. "A practical method for the acylation of 2-imidazolidinone and 2-oxazolidinone chiral auxiliaries with 2-bromoacyl halides". Synthetic Communications 31 21 (2001): 3241-3254. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034815665&partnerID=MN8TOARS.
    10.1081/SCC-100106033
  250. Caddick, S.; Afonso, C.A.M.; Candeias, S.X.; Hitchcock, P.B.; Jenkins, K.; Murtagh, L.; Pardoe, D.; et al. "Synthesis of a-amino esters by dynamic kinetic resolution of a-haloacyl imidazolidinones". Tetrahedron 57 30 (2001): 6589-6605. http://www.scopus.com/inward/record.url?eid=2-s2.0-17844393636&partnerID=MN8TOARS.
    10.1016/S0040-4020(01)00550-6
  251. Norton Matos, M.R.P.; Afonso, C.A.M.; Batey, R.A.. "Synthesis of 3-aminopyrrolidines and piperidines from endocyclic enamine derivatives". Tetrahedron Letters 42 40 (2001): 7007-7010. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035479540&partnerID=MN8TOARS.
    10.1016/S0040-4039(01)01433-2
  252. Sousa, H.A.; Afonso, C.A.M.; Crespo, J.G.. "Kinetic study of the enantioselective hydrolysis of a meso-diester using Pig Liver Esterase". Journal of Chemical Technology and Biotechnology 75 8 (2000): 707-714. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034254587&partnerID=MN8TOARS.
    10.1002/1097-4660(200008)75:8<707::AID-JCTB278>3.0.CO;2-3
  253. Afonso, C.A.M.; Vieira, N.M.L.; Motherwell, W.B.. "Observations on the use of triphenylphosphonium bromide as a mild and quantifiable source of hydrogen bromide for chemoselective ring opening of epoxides to bromohydrins". Synlett 3 (2000): 382-384. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034050783&partnerID=MN8TOARS.
  254. Sousa, H.A.; Crespo, J.G.; Afonso, C.A.M.. "Asymmetric hydrolysis of a meso-diester using pig liver esterase immobilised in hollow fibre ultrafiltration membrane". Tetrahedron Asymmetry 11 4 (2000): 929-934. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034629039&partnerID=MN8TOARS.
    10.1016/S0957-4166(00)00009-4
  255. Afonso, C.A.M.; Barros, M.T.; Maycock, C.D.. "Addition of organolithium reagents to cinnamic acids". Tetrahedron 55 3 (1999): 831-846. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033555767&partnerID=MN8TOARS.
  256. Matos, M.R.P.N.; Afonso, C.A.M.; McGarvey, T.; Lee, P.; Batey, R.A.. "Synthesis of substituted pyrrolidines by sequential radical cyclization and N-acyliminium ion reactions". Tetrahedron Letters 40 52 (1999): 9189-9193. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033601399&partnerID=MN8TOARS.
    10.1016/S0040-4039(99)01971-1
  257. Cabrita, E.J.; Candeias, S.X.; Ramos, A.M.; Afonso, C.A.M.; Santos, A.G.. "Novel acid catalysed 1,4-addition-type ring-opening polymerisation of cyclic phosphorimidates". Tetrahedron Letters 40 1 (1999): 137-140. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032889892&partnerID=MN8TOARS.
    10.1016/S0040-4039(98)80040-3
  258. Afonso, C.A.M.. "Studies on the transformation of azido-group to N-(t-butoxycarbonyl)amino group via Staudinger reaction". Synthetic Communications 28 2 (1998): 261-276. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031886104&partnerID=MN8TOARS.
    10.1080/00397919808005719
  259. Caddick, S.; Jenkins, K.; Treweeke, N.; Candeias, S.X.; Afonso, C.A.M.. "Rationalising diastereoselection in the dynamic kinetic resolution of a-haloacyl imidazolidinones". Tetrahedron Letters 39 15 (1998): 2203-2206. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032499048&partnerID=MN8TOARS.
    10.1016/S0040-4039(98)00175-0
  260. Afonso, C.A.M.. "Transformation of azido-group to n-(t-butoxycarbonyl)amino group under mild conditions via staudinger reaction". Tetrahedron Letters 36 48 (1995): 8857-8858. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028793366&partnerID=MN8TOARS.
    10.1016/0040-4039(95)01838-9
  261. M. Afonso, C.; Teresa Barros, M.; S. Godinho, L.; D. Maycock, C.. "The mechanism of the Mitsunobu azide modification and the effect of additives on the rate of hydroxyl group activation.". Tetrahedron 50 32 (1994): 9671-9678. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028041388&partnerID=MN8TOARS.
    10.1016/S0040-4020(01)85535-6
  262. Afonso, C.A.M.; Barros, M.T.; Godinho, L.S.; Maycock, C.D.. "Stereocontrolled synthesis of the 4-hydroxy-5-methyl-2(3H)-dihydrofuranone isomers". Tetrahedron 49 20 (1993): 4283-4292. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027180988&partnerID=MN8TOARS.
    10.1016/S0040-4020(01)85744-6
  263. Afonso, C.A.M.; Motherwell, W.B.; Roberts, L.R.. "Observations on the selective deoxygenation of epoxides to olefins with chlorotrimethylsilane and zinc.". Tetrahedron Letters 33 23 (1992): 3367-3370. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026741964&partnerID=MN8TOARS.
    10.1016/S0040-4039(00)92090-2
  264. Afonso, C.A.M.; Motherwell, W.B.; O'Shea, D.M.; Roberts, L.R.. "An improved method for the generation of organozinc carbenoids and its application in dicarbonyl coupling reactions". Tetrahedron Letters 33 27 (1992): 3899-3902. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026651403&partnerID=MN8TOARS.
    10.1016/S0040-4039(00)74814-3
  265. Afonso, C.A.M.; Barros, M.T.; Godinho, L.S.; Maycock, C.D.. "Synthesis of 2,3-dihydro-1,4-dithiins and 2-alkylidene-1,4-dithianes by 1,2-sulfur migration in 2-(1-hydroxyalkyl)-1,3-dithiolanes". Synthesis 7 (1991): 575-580. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025854270&partnerID=MN8TOARS.
  266. Afonso, C.M.; Barros, M.T.; Godinho, L.; Maycock, C.D.. "A useful method for preparing optically active secondary alcohols: A short enantiospecific synthesis of (R)- and (S)-sulcatol". Tetrahedron Letters 30 20 (1989): 2707-2708. http://www.scopus.com/inward/record.url?eid=2-s2.0-0001848042&partnerID=MN8TOARS.
    10.1016/S0040-4039(00)99105-6
  267. Afonso, C.M.; Barros, M.T.; Maycock, C.D.. "The reactivity of silyl ethers to the swern reagent". Journal of the Chemical Society, Perkin Transactions 1 (1987): 1221-1223. http://www.scopus.com/inward/record.url?eid=2-s2.0-37049089890&partnerID=MN8TOARS.
Capítulo de livro
  1. Rosatella, A.A.; Afonso, C.A.M.. "CHAPTER 2: The dissolution of biomass in ionic liquids towards pre-treatment approach". 2016.
    10.1039/9781782622598-00038
  2. Candeias, N.R.; Trindade, A.F.; Gois, P.M.P.; Afonso, C.A.M.. "The Wolff Rearrangement". In Comprehensive Organic Synthesis II (Second Edition). Oxford : Elsevier, 2014. p. 944-991.. 2014.
    10.1016/B978-0-08-097742-3.00325-6
  3. Rosatella, Andreia A.; Afonso, Carlos A. M.. "Metal-Catalyzed Oxidation of C–X (X = S, O) in Ionic Liquids". In Ionic Liquids (ILs) in Organometallic Catalysis, 163-184. Springer Berlin Heidelberg, 2013.
    10.1007/3418_2013_67
  4. A. Trindade; Gibson, Vernon; Carlos Monteiro; Carlos A. M. Afonso. "Chapter 3 – “Recyclable stereoselective catalysts.”". In “Catalytic Methods in Asymmetric Synthesis: Advanced Materials, Techniques, and Applications” Ed. M. Gruttadauria, Francesco Giacalone, Wiley 2012. Wiley, 2012.
  5. Frade, R.F.M.; Matias, A.; Branco, L.C.; Lourenço, N.M.T.; Rosa, J.N.; Afonso, C.A.M.; Duarte, C.M.M.. "Toxicological evaluation of ionic liquids: Effect of ionic liquids on human colon carcinoma HT-29 and CaCo-2 cell lines". In Ionic Liquid Applications: Pharmaceuticals, Therapeutics, and Biotechnology. American Chemical Society, 2010.
    10.1021/bk-2010-1038.ch011
  6. Rosa, J.N.; Afonso, C.A.M.. "Organocatalyzed asymmetric Michael reaction in ionic liquids-carbon dioxide". In ACS Symposium Series 950. 2007.
  7. Schäfer, T.; Branco, L.C.; Fortunato, R.; Izák, P.; Rodrigues, C.M.; Afonso, C.A.M.; Crespo, J.G.. "Opportunities for membrane separation processes using ionic liquids". In Ionic Liquids IIIB: Fundamentals, Progress, Challenges, and Opportunities, 97-110. American Chemical Society, 2005.
Livro
  1. Afonso, Carlos A. M.. Compreensive Organic Chemsitry Experiments for the Laboratory Classroom. RSC. 2017.
  2. Monteiro, C.M.; Trindade, A.F.; Gois, P.M.P.; Afonso, C.A.M.. Recyclable Stereoselective Catalysts. 2011.
    10.1002/9781118087992.ch1
  3. Luis, P.; Albo, J.; Afonso, C.; Irabien, A.. Environmental risks of magnetic ionic liquids: Ecotoxicity (EC50, Vibrio fischeri). 2011.
  4. Afonso, Carlos A. M.. Green Separation Processes: Fundamentals and Applications. 2006.
    10.1002/3527606602
  5. Afonso, C.A.M.; Crespo, J.G.. Concluding Remarks. 2006.
    10.1002/3527606602.ch4
Distinções

Prémio

2022 Fellow da Chemistry Europe (2020/21)
Chemistry Europe, Países Baixos
2016 Prémios Científico Universidade de Lisboa / Caixa Geral de Depósitos 2016; Área de Química, Engenharia Química, Engenharia Farmacêutica.
Universidade de Lisboa, Portugal
2016 Prize, 2016 of Ibero-americano de Química Orgânica
2009 Prémio Científico UTL/Santander Totta 2009, Área da Química
Universidade de Lisboa, Portugal
2008 Prémio BES Inovação 2008, categoria de Energia