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Francisco Javier Enguita. Concluiu o(a) Doutoramento em Ciências Farmacêuticas em 2000 pelo(a) Universidad de Salamanca, Doctor em Microbiologia y Genética em 1998/10/05 pelo(a) Universidad de Salamanca Facultad de Farmacia, Master Universitario em Microbiologia em 1992/06/01 pelo(a) Universidad de Granada Facultad de Farmacia e Bachelor em Farmacia em 1991/07/30 pelo(a) Universidad de Granada Facultad de Farmacia. É Professor Auxiliar no(a) Universidade de Lisboa Faculdade de Medicina. Publicou 95 artigos em revistas especializadas. Possui 2 capítulo(s) de livros e 3 livro(s). Orientou 6 tese(s) de doutoramento e coorientou 2. Orientou 2 dissertação(ões) de mestrado e coorientou 5. Recebeu 2 prémio(s) e/ou homenagens. Participa e/ou participou como Investigador em 8 projeto(s) e Investigador responsável em 4 projeto(s). Atua na(s) área(s) de Ciências Médicas e da Saúde com ênfase em Medicina Básica com ênfase em Genética Humana, Ciências Naturais com ênfase em Ciências Biológicas com ênfase em Biologia Celular, Ciências Naturais com ênfase em Ciências Biológicas com ênfase em Genética e Hereditariedade e Ciências Naturais com ênfase em Ciências Biológicas com ênfase em Bioquímica. Nas suas atividades profissionais interagiu com 448 colaborador(es) em coautorias de trabalhos científicos. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: non-coding RNA; Health Sciences - Infection and Microbiology; .
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Identificação

Identificação pessoal

Nome completo
Francisco Javier Enguita

Nomes de citação

  • Enguita, Francisco J.

Identificadores de autor

Ciência ID
B215-8D49-3218
ORCID iD
0000-0002-8072-8557
Google Scholar ID
https://scholar.google.com/citations?user=pIZG8JsAAAAJ&hl=en&oi=ao
Researcher Id
A-2347-2009
Scopus Author Id
6602119231

Endereços de correio eletrónico

  • fenguita@medicina.ulisboa.pt (Profissional)
  • fenguita@medicina.ulisboa.pt (Profissional)

Moradas

  • Instituto de Bioquímica, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028, Lisboa, Lisboa, Portugal (Profissional)
  • Rua Vitor Damas nº6, 4º Esq, 1600-410, Lisboa, Lisboa, Portugal (Pessoal)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Genética Humana
  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Naturais - Ciências Biológicas - Genética e Hereditariedade
  • Ciências Naturais - Ciências Biológicas - Bioquímica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Espanhol; Castelhano (Idioma materno)
Português Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
1993/01/01 - 1998/10/05
Concluído
 Microbiologia y Genética (Doctor)
Especialização em Microbiologia y Genética
Universidad de Salamanca Facultad de Farmacia, Espanha
1991/08/01 - 1992/06/01
Concluído
 Microbiologia (Master Universitario)
Especialização em Microbiologia y Biotecnologia
Universidad de Granada Facultad de Farmacia, Espanha
1986/09/01 - 1991/07/30
Concluído
 Farmacia (Bachelor)
Especialização em Licenciatura en Farmacia rama sanitaria
Universidad de Granada Facultad de Farmacia, Espanha
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2006/04/01 - 2008/06/30 Investigador Contratado (Investigação) Instituto de Medicina Molecular, Portugal
2004/01/01 - 2006/03/31 Investigador principal (carreira) (Investigação) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2001/01/01 - 2003/12/31 Pós-doutorado (Investigação) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
1999/03/01 - 2001/03/31 Pós-doutorado (Investigação) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2008/04/01 - Atual Professor Auxiliar (Docente Universitário) Universidade de Lisboa Faculdade de Medicina, Portugal
Universidade de Lisboa Faculdade de Medicina, Portugal
2000/10/01 - 2007/10/01 Professor Auxiliar (Docente Universitário) Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
Projetos

Projeto

Designação Financiadores
2021/01/01 - 2025/12/31 Rede de Investigação em Saúde: do Laboratório à Saúde Comunitária
LA/P/0053/2020
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Universidade do Algarve, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Ciências, Portugal

Universidade da Madeira, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Universidade de Lisboa Centro Cardiovascular da Universidade de Lisboa, Portugal

Universidade de Aveiro, Portugal

Centro de Investigação em Tecnologias e Serviços de Saúde, Portugal

Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal

Escola Superior de Enfermagem do Porto, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Universidade NOVA de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2021/01/01 - 2025/12/31 Institute of Molecular Medicine João Lobo Antunes
LA/P/0082/2020
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2021/01/01 - 2025/12/31 Health Research Network: From Lab to Community Health
10.54499/LA/P/0053/2020
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Universidade do Algarve, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Ciências, Portugal

Universidade da Madeira, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Universidade de Lisboa Centro Cardiovascular da Universidade de Lisboa, Portugal

Universidade de Aveiro, Portugal

Centro de Investigação em Tecnologias e Serviços de Saúde, Portugal

Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal

Escola Superior de Enfermagem do Porto, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Universidade NOVA de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2022/02/01 - 2025/01/31 Towards the development of a nanoparticle for early diagnosis of Alzheimer’s Disease, based on the reversible translocation of the blood brain barrier.
PTDC/BTM-MAT/2472/2021
10.54499/PTDC/BTM-MAT/2472/2021
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Universidade Nova de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2023/03/06 - 2024/09/05 Early biomarkers to stop vascular dysfunction associated with obesity and type 2 diabetes
2022.04526.PTDC
10.54499/2022.04526.PTDC
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/10 - 2021/09 Unraveling the role of circular RNAs in the establishment of permanent atrial fibrillation
PTDC/MED-GEN/29389/2017
Investigador responsável
Fundação para a Ciência e a Tecnologia
2018/10 - 2021/09 Molecular Mechanisms that maintain Mitochondrial Homeostasis in Brain
PTDC/BIA-CEL/31230/2017
PTDC/BIA-CEL/31230/2017
Investigador
Fundação para a Ciência e a Tecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/06/01 - 2021/05/31 Plasmodium cross-stage interplay modulates Severe Malaria pathology
PTDC/MED-IMU/28664/2017
PTDC/MED-IMU/28664/2017
Investigador
Fundação para a Ciência e a Tecnologia
2019/01/01 - 2019/12/31 Centro Cardiovascular da Universidade de Lisboa
UID/IC/00306/2019
Universidade de Lisboa Centro Cardiovascular da Universidade de Lisboa, Portugal

Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2019/01/01 - 2019/12/31 Instituto de Medicina Molecular
UID/BIM/50005/2019
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2016/06/01 - 2018/05/30 Role of microRNAs on the left ventricle reverse- remodeling after aortic valve replacement in patients with aortic valve stenosis
PTDC/DTP-EPI/6127/2014
PTDC/DTP-EPI/6127/2014
Investigador
Fundação para a Ciência e a Tecnologia
2016/06 - 2018/05 Peptides for blood-brain barrier transmigration and drug delivery - novel therapies for the central nervous system
PTDC/BBB-NAN/1578/2014
PTDC/BBB-NAN/1578/2014
Investigador
Fundação para a Ciência e a Tecnologia
2016/06 - 2018/04 Dissection of microRNA-mediated post-transcriptional regulation of T cell differentiation
PTDC/BEX-BCM/3592/2014
PTDC/BEX-BCM/3592/2014
Investigador
Fundação para a Ciência e a Tecnologia
2015/05 - 2018/04 Evasion of host-mediated autophagy: mechanisms of Plasmodium survival in the liver-stage of infection
PTDC/BIM-MEC/1342/2014
PTDC/BIM-MEC/1342/2014
Investigador
Fundação para a Ciência e a Tecnologia
2014/01/01 - 2015/06/30 Exploring new therapeutic approaches for Hypertrophic Cardiomyopathy
EXPL/BIM-MEC/0201/2013
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2013/06/01 - 2015/05/31 Do miRNAs and TAL1 crosstalk?. New insights into the regulation and function of a major T-cell oncogene
PTDC/BIM-ONC/1548/2012
PTDC/BIM-ONC/1548/2012
Investigador
Fundação para a Ciência e a Tecnologia
2011/01/01 - 2013/02/17 Projecto Estratégico - LA 5 - 2011-2012
PEst-OE/SAU/LA0005/2011
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2010/06 - 2012/05 Cell membrane features in HIV entry and its inhibition
PTDC/QUI-BIQ/104787/2008
PTDC/QUI-BIQ/104787/2008
Investigador
Fundação para a Ciência e a Tecnologia
2004/09/01 - 2007/08/31 Role of the interaction between AgfA and AgfB proteins from Salmonella enterica serovar Typhimurium in the surface polimerization of the amyloid-like thin aggregative fimbriae.
info:eu-repo/grantAgreement/FCT/3599-PPCDT/82300/PT
Investigador responsável
Fundação para a Ciência e a Tecnologia
2002/01/01 - 2004/12/31 Structural Genomics in Europe, Structural genomics of the human pathogen Campylobacter jejuni and Klebsiella pneumoniae
QLG2-CT-2002-00988
Investigador responsável
Community Research and Development Information Programme
2002/01 - 2004/12 Structural characterization of MrkD protein from Klebsiella pneumoniae: implications on the epithelial adhesion properties of the microorganism
POCTI/ESP/46428/2002
POCTI/ESP/46428/2002
Investigador responsável
Fundação para a Ciência e a Tecnologia
Produções

Publicações

Artigo em conferência
  1. Marques, Carla; Baptista, Rui; Zuzarte, Mónica; Enguita, Francisco J.; Girão, Henrique. "The role of circulating miR-424 as marker of disease severity in pulmonary hypertension". Trabalho apresentado em European Journal of Clinical Investigation: 53rd ESCI2019 Annual Scientific Meeting of the European Society for Clinical Investigation, Coimbra, 2019.
    Publicado • 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3818
Artigo em revista
  1. Elsa D. Silva; Daniel Pereira-Sousa; Francisco Ribeiro-Costa; Rui Cerqueira; Francisco J. Enguita; Rita N. Gomes; João Dias-Ferreira; et al. "Pericardial Fluid Accumulates microRNAs That Regulate Heart Fibrosis after Myocardial Infarction". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms25158329.
    10.3390/ijms25158329
  2. Fonseca-Gomes, João; Ribeiro-Rodrigues, Leonor; Mouro, Francisco M.; Paulo SP; Tanqueiro SR; Belo RF ; Miranda-Lourenço, Catarina; et al. Autor correspondente: Diógenes, MJ. "TrkB-ICD fragment promotes transcriptomic, proteomic, and synaptic alterations, driving recognition memory impairment in healthy rodents.". in preparation (2024):
  3. Patrick K. T. Shiu; Johanna K. DiStefano; Suresh K. Alahari; Francisco J. Enguita; Mark W. Feinberg; Nikolaos Sideris; Salih Bayraktar; et al. "The Non-Coding RNA Journal Club: Highlights on Recent Papers—13". Non-Coding RNA (2023): https://doi.org/10.3390/ncrna9060076.
    10.3390/ncrna9060076
  4. Francisco J. Enguita; Ana Lúcia Leitão; John S. Mattick. "RNA Regulatory Networks 2.0". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24109001.
    10.3390/ijms24109001
  5. Priscilla L. S. Boon; Ana S. Martins; Xin Ni Lim; Francisco J. Enguita; Nuno C. Santos; Peter J. Bond; Yue Wan; Ivo C. Martins; Roland G. Huber. "Dengue Virus Capsid Protein Facilitates Genome Compaction and Packaging". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24098158.
    10.3390/ijms24098158
  6. Francisco J. Enguita; Sofia Pereira; Ana Lúcia Leitão. "Transcriptomic Analysis of Acetaminophen Biodegradation by Penicillium chrysogenum var. halophenolicum and Insights into Energy and Stress Response Pathways". Journal of Fungi (2023): https://doi.org/10.3390/jof9040408.
    10.3390/jof9040408
  7. Tania Martins-Marques; Marina C Costa; Steve Catarino; Isaura Simoes; Trond Aasen; Francisco J Enguita; Henrique Girao. "Cx43-mediated sorting of miRNAs into extracellular vesicles". EMBO reports (2022): https://doi.org/10.15252/embr.202154312.
    10.15252/embr.202154312
  8. Ana Lúcia Leitão; Francisco J. Enguita. "A Structural View of miRNA Biogenesis and Function". Non-Coding RNA (2022): https://doi.org/10.3390/ncrna8010010.
    10.3390/ncrna8010010
  9. Jairo A. Pinzon Cortes; Assam El-Osta; Giulia Fontemaggi; Nicholas Delihas; Katsuki Miyazaki; Ajay Goel; Mira BRAZANE; et al. "The Non-Coding RNA Journal Club: Highlights on Recent Papers". Non-Coding RNA 8 1 (2022): 3. https://www.mdpi.com/2311-553X/8/1/3.
    Acesso aberto • Publicado • 10.3390/ncrna8010003
  10. Enguita, Francisco J.; Leitao, Ana Lucia; McDonald, J. Tyson; Zaksas, Viktorija; Das, Saswati; Galeano, Diego; Taylor, Deanne; et al. "The interplay between lncRNAs, RNA-binding proteins and viral genome during SARS-CoV-2 infection reveals strong connections with regulatory events involved in RNA metabolism and immune response". Theranostics (2022): https://publons.com/wos-op/publon/51938342/.
    10.7150/THNO.73268
  11. Ana Lúcia Leitão; Francisco J. Enguita. "Systematic Structure-Based Search for Ochratoxin-Degrading Enzymes in Proteomes from Filamentous Fungi". Biomolecules 11 7 (2021): 1040-1040. https://doi.org/10.3390/biom11071040.
    10.3390/biom11071040
  12. Tiago Pereira-da-Silva; Patrícia Napoleão; Marina C. Costa; André F. Gabriel; Mafalda Selas; Filipa Silva; Francisco J. Enguita; Rui Cruz Ferreira; Miguel Mota Carmo. "Association between miR-146a and Tumor Necrosis Factor Alpha (TNF-a) in Stable Coronary Artery Disease". Medicina (2021): https://doi.org/10.3390/medicina57060575.
    10.3390/medicina57060575
  13. William B. Miller, Jr.; Francisco J. Enguita; Ana Lúcia Leitão. "Non-Random Genome Editing and Natural Cellular Engineering in Cognition-Based Evolution". Cells 10 5 (2021): 1125-1125. https://doi.org/10.3390/cells10051125.
    10.3390/cells10051125
  14. Sema Misir; Ceylan Hepokur; Yuksel Aliyazicioglu; Francisco J. Enguita. "Biomarker potentials of miRNA-associated circRNAs in breast cancer (MCF-7) cells: an in vitro and in silico study". Molecular Biology Reports (2021): https://doi.org/10.1007/s11033-021-06281-5.
    10.1007/s11033-021-06281-5
  15. Witek P; Enguita FJ; Grzesiak M; Costa MC; Gabriel A; Koziorowski M; Slomczynska M; Knapczyk-Stwora K. "Effects of neonatal exposure to methoxychlor on corpus luteum in gilts: A transcriptomic analysis.". Molecular reproduction and development (2021): http://europepmc.org/abstract/med/33655673.
    10.1002/mrd.23463
  16. Ana Lúcia Leitão; Francisco J. Enguita. "Structural Insights into Carboxylic Polyester-Degrading Enzymes and Their Functional Depolymerizing Neighbors". International Journal of Molecular Sciences 22 5 (2021): 2332-2332. https://doi.org/10.3390/ijms22052332.
    Publicado • 10.3390/ijms22052332
  17. Tiago Pereira-da-Silva; Patrícia Napoleão; Marina C. Costa; André F. Gabriel; Mafalda Selas; Filipa Silva; Francisco J. Enguita; Rui Cruz Ferreira; Miguel Mota Carmo. "Cigarette Smoking, miR-27b Downregulation, and Peripheral Artery Disease: Insights into the Mechanisms of Smoking Toxicity". Journal of Clinical Medicine 10 4 (2021): 890-890. https://doi.org/10.3390/jcm10040890.
    10.3390/jcm10040890
  18. Tiago Pereira-da-Silva; Patrícia Napoleão; Marina C. Costa; André F. Gabriel; Mafalda Selas; Filipa Silva; Francisco J. Enguita; Rui Cruz Ferreira; Miguel Mota Carmo. "Circulating miRNAs Are Associated with the Systemic Extent of Atherosclerosis: Novel Observations for miR-27b and miR-146". Diagnostics 11 2 (2021): 318-318. https://doi.org/10.3390/diagnostics11020318.
    10.3390/diagnostics11020318
  19. Nayla de Souza Pitangui; Junya de Lacorte Singulani; Janaina de Cássia Orlandi Sardi; Paula Carolina de Souza; Gabriela Rodríguez-Arellanes; Blanca Estela García-Pérez; Francisco Javier Enguita; et al. "Differential miRNA Expression in Human Macrophage-Like Cells Infected with Histoplasma capsulatum Yeasts Cultured in Planktonic and Biofilm Forms". Journal of Fungi (2021): https://doi.org/10.3390/jof7010060.
    10.3390/jof7010060
  20. Miranda, Hugo Vicente; Szego, Eva M.; Oliveira, Luis M. A.; Breda, Carlo; Darendelioglu, Ekrem; de Oliveira, Rita M.; Ferreira, Diana G.; et al. "Glycation potentiates alpha-synuclein-associated neurodegeneration in synucleinopathies (vol 140, pg 1399, 2017)". Brain (2021): https://publons.com/publon/50474925/.
    10.1093/BRAIN/AWAB175
  21. Medeiros, A. M.; Enguita, F. J.; Bourbon, M.. "MIRNA TARGET-BINDING SITES AS REGULATORS OF GENES INVOLVED IN THE LIPID METABOLISM MIGHT EXPLAIN THE HYPERCHOLESTEROLAEMIA IN FH PATIENTS". Atherosclerosis (2021): https://publons.com/publon/52924754/.
  22. McDonald, J. Tyson; Enguita, Francisco J.; Taylor, Deanne; Griffin, Robert J.; Priebe, Waldemar; Emmett, Mark R.; Sajadi, Mohammad M.; et al. "Role of miR-2392 in driving SARS-CoV-2 infection". Cell Reports (2021): https://publons.com/wos-op/publon/49864811/.
    10.1016/J.CELREP.2021.109839
  23. Costa, M.; Toro, R.; Calderon, M.; Pacheco, G.; Perez Navarro, A.; Mangas, A.; Enguita, F. J.. "CIRCULATING CIRCRNA AS NOVEL BIOMARKERS IN THE ETIOLOGICAL BASED DIAGNOSIS OF DILATED CARDIOMYOPATHY". Atherosclerosis (2021): https://publons.com/publon/51725746/.
  24. Costa, Marina C.; Calderon-Dominguez, Maria; Mangas, Alipio; Campuzano, Oscar; Sarquella-Brugada, Georgia; Ramos, Monica; Quezada-Feijoo, Maribel; et al. "Circulating circRNA as biomarkers for dilated cardiomyopathy etiology". Journal of Molecular Medicine (2021): https://publons.com/publon/49325286/.
    10.1007/S00109-021-02119-6
  25. Sonali Setua; Francisco J. Enguita; Ângelo Ferreira Chora; Harish Ranga-prasad; Aparajita Lahree; Sofia Marques; Varadharajan Sundaramurthy; Maria M. Mota. "Disrupting Plasmodium UIS3–host LC3 interaction with a small molecule causes parasite elimination from host cells". Communications Biology (2020): https://doi.org/10.1038/s42003-020-01422-1.
    10.1038/s42003-020-01422-1
  26. Wang HL; Wang HR; Liang Y; Hu AN; Enguita FJ; Zhou XG; Dong J. "Hsa_circ_0006571 promotes spinal metastasis through sponging microRNA-138 to regulate sirtuin 1 expression in lung adenocarcinoma.". Translational lung cancer research (2020): http://europepmc.org/abstract/med/33489803.
    10.21037/tlcr-20-1250
  27. Mello-Vieira J; Enguita FJ; de Koning-Ward TF; Zuzarte-Luís V; Mota MM. "Plasmodium translocon component EXP2 facilitates hepatocyte invasion.". Nature communications (2020): http://europepmc.org/abstract/med/33159090.
    10.1038/s41467-020-19492-4
  28. Singulani JL; Silva JFD; Gullo FP; Costa MC; Fusco-Almeida AM; Enguita FJ; Mendes-Giannini MJS. "Fungal-host interactions: insights into microRNA in response to Paracoccidioides species.". Memorias do Instituto Oswaldo Cruz (2020): http://europepmc.org/abstract/med/32756740.
    10.1590/0074-02760200238
  29. Sema Misir; Ceylan Hepokur; Yüksel Aliyazicioglu; Francisco J. Enguita. "Circular RNAs serve as miRNA sponges in breast cancer". Breast Cancer (2020): https://doi.org/10.1007/s12282-020-01140-w.
    10.1007/s12282-020-01140-w
  30. Ferrasi AC; Fernandez GJ; Grotto RMT; Silva GF; Goncalves J; Costa MC; Enguita FJ; Pardini MIMC. "New LncRNAs in Chronic Hepatitis C progression: from fibrosis to hepatocellular carcinoma.". Scientific reports (2020): http://europepmc.org/abstract/med/32555359.
    10.1038/s41598-020-66881-2
  31. Robinson EL; Gomes CPDC; Potocnjak I; Hellemans J; Betsou F; de Gonzalo-Calvo D; Stoll M; et al. "A Year in the Life of the EU-CardioRNA COST Action: CA17129 Catalysing Transcriptomics Research in Cardiovascular Disease.". Non-coding RNA (2020): http://europepmc.org/abstract/med/32443579.
    10.3390/ncrna6020017
  32. Vicente Miranda H; Chegão A; Oliveira MS; Fernandes Gomes B; Enguita FJ; Outeiro TF; Hugo Vicente Miranda; et al. "Hsp27 reduces glycation-induced toxicity and aggregation of alpha-synuclein.". FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2020): http://europepmc.org/abstract/med/32259355.
    10.1096/fj.201902936r
  33. Ana Lúcia Leitão; Marina C. Costa; André F. Gabriel; Francisco J. Enguita; Leitão AL; Costa MC; Gabriel AF; Enguita FJ. "Interspecies Communication in Holobionts by Non-Coding RNA Exchange". International Journal of Molecular Sciences (2020): https://www.mdpi.com/1422-0067/21/7/2333.
    10.3390/ijms21072333
  34. André F. Gabriel; Marina C. Costa; Francisco J. Enguita. "Circular RNA-Centered Regulatory Networks in the Physiopathology of Cardiovascular Diseases". International Journal of Molecular Sciences 21 2 (2020): 456-456. https://doi.org/10.3390/ijms21020456.
    10.3390/ijms21020456
  35. Amado T; Amorim A; Enguita FJ; Romero PV; Inácio D; de Miranda MP; Winter SJ; et al. "MicroRNA-181a regulates IFN-¿ expression in effector CD8+ T cell differentiation.". Journal of molecular medicine (Berlin, Germany) (2020): http://europepmc.org/abstract/med/32002568.
    10.1007/s00109-019-01865-y
  36. Silva, T. P. D.; Costae, M. G.; Gabriel, A. F.; Selas, M.; Silva, F.; Enguita, F. J.; Napoleao, P.; et al. "Insights from microRNAs into the pathophysiology of coronary and multiterritorial atherosclerosis". European Heart Journal (2020): https://publons.com/publon/39060452/.
    10.1093/EHJCI/EHAA946.1253
  37. Gabriel AF; Costa MC; Enguita FJ; Leitão AL. "Si vis pacem para bellum: A prospective in silico analysis of miRNA-based plant defenses against fungal infections". Plant science : an international journal of experimental plant biology (2019): http://europepmc.org/abstract/AGR/IND606617093.
    10.1016/j.plantsci.2019.110241
  38. Faustino AF; Martins AS; Karguth N; Artilheiro V; Enguita FJ; Ricardo JC; Santos NC; Martins IC. "Structural and Functional Properties of the Capsid Protein of Dengue and Related Flavivirus.". International journal of molecular sciences (2019): http://europepmc.org/abstract/med/31398956.
    10.3390/ijms20163870
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  46. Lourencetti NMS; Wolf IR; Lacerda MPF; Valente GT; Zanelli CF; Santoni MM; Mendes-Giannini MJS; Enguita FJ; Fusco-Almeida AM. "Transcriptional profile of a bioethanol production contaminant Candida tropicalis.". AMB Express (2018): http://europepmc.org/abstract/med/30311091.
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  47. Esteves JV; Yonamine CY; Pinto-Junior DC; Gerlinger-Romero F; Enguita FJ; Machado UF. "Diabetes Modulates MicroRNAs 29b-3p, 29c-3p, 199a-5p and 532-3p Expression in Muscle: Possible Role in GLUT4 and HK2 Repression.". Frontiers in endocrinology (2018): http://europepmc.org/abstract/med/30258406.
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  62. Cortez-Dias N; Costa MC; Carrilho-Ferreira P; Silva D; Jorge C; Calisto C; Pessoa T; et al. "CORRIGENDUM: Circulating miR-122-5p/miR-133b Ratio Is a Specific Early Prognostic Biomarker in Acute Myocardial Infarction.". (2017): http://europepmc.org/abstract/med/28344209.
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  63. Real, E.; Rodrigues, L.; Cabal, G.G.; Enguita, F.J.; Mancio-Silva, L.; Mello-Vieira, J.; Beatty, W.; et al. "Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes". Nature Microbiology (2017): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-85033394934&partnerID=MN8TOARS.
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  76. Enguita FJ; Costa MC; Fusco-Almeida AM; Mendes-Giannini MJ; Leitão AL. "Transcriptomic Crosstalk between Fungal Invasive Pathogens and Their Host Cells: Opportunities and Challenges for Next-Generation Sequencing Methods.". Journal of fungi (Basel, Switzerland) (2016): http://europepmc.org/abstract/med/29376924.
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  88. Pereira, P.; Enguita, F.J.; Ferreira, J.; Leitão, A.L.. "DNA damage induced by hydroquinone can be prevented by fungal detoxification". Toxicology Reports 1 (2014): 1096-1105. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922751886&partnerID=MN8TOARS.
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  108. Aragão, D.; Marques, A.R.; Frazão, C.; Enguita, F.J.; Carrondo, M.A.; Fialho, A.M.; Sá-Correia, I.; Mitchell, E.P.. "Cloning, expression, purification, crystallization and preliminary structure determination of glucose-1-phosphate uridylyltransferase (UgpG) from Sphingomonas elodea ATCC 31461 bound to glucose-1-phosphate". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 62 9 (2006): 930-934. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748517226&partnerID=MN8TOARS.
    10.1107/S1744309106030107
  109. Enguita, F.J.; Pohl, E.; Turner, D.L.; Santos, H.; Carrondo, M.A.. "Structural evidence for a proton transfer pathway coupled with haem reduction of cytochrome c¿ from Methylophilus methylotrophus". Journal of Biological Inorganic Chemistry 11 2 (2006): 189-196. http://www.scopus.com/inward/record.url?eid=2-s2.0-32444435237&partnerID=MN8TOARS.
    10.1007/s00775-005-0065-6
  110. Rodrigues, M.L.; Archer, M.; Martel, P.; Miranda, S.; Thomaz, M.; Enguita, F.J.; Baptista, R.P.; et al. "Crystal structures of the free and sterol-bound forms of ß-cinnamomin". Biochimica et Biophysica Acta - Proteins and Proteomics 1764 1 (2006): 110-121. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644834490&partnerID=MN8TOARS.
    10.1016/j.bbapap.2005.09.008
  111. Enguita, F.J.; Marçal, D.; Martins, L.O.; Grenha, R.; Henriques, A.O.; Lindley, P.F.; Carrondo, M.A.. "Substrate and dioxygen binding to the endospore coat laccase from Bacillus subtilis". Journal of Biological Chemistry 279 22 (2004): 23472-23476. http://www.scopus.com/inward/record.url?eid=2-s2.0-2542467902&partnerID=MN8TOARS.
    10.1074/jbc.M314000200
  112. Enguita, Francisco J.; Marcal, David; Martins, Ligia O.; Grenha, Rosa; Bento, Isabel; Gato, Goncalo; Lindley, Peter F.; Carrondo, Maria Armenia. "Substrate and dioxygen binding to an endospore coat laccase from Bacillus subtilis". Acta Crystallographica Section A: Foundations and Advances (2004): https://publons.com/publon/47771715/.
    10.1107/S0108767304096813
  113. Enguita, F.J.; Martins, L.O.; Henriques, A.O.; Carrondo, M.A.. "Crystal structure of a bacterial endospore coat component: A laccase with enhanced thermostability properties". Journal of Biological Chemistry 278 21 (2003): 19416-19425. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038143259&partnerID=MN8TOARS.
    10.1074/jbc.M301251200
  114. Enguita, F.J.; Rodrigues, L.; Archer, M.; Sieker, L.; Rodrigues, A.; Pohl, E.; Turner, D.L.; Santos, H.; Carrondo, M.A.. "Crystallization and preliminary X-ray characterization of cytochrome c¿ from the obligate methylotroph Methylophilus methylotrophus". Acta Crystallographica - Section D Biological Crystallography 59 3 (2003): 580-583. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037348494&partnerID=MN8TOARS.
    10.1107/S0907444903001045
  115. Enguita, F.J.; Matias, P.M.; Martins, L.O.; Plácido, D.; Henriques, A.O.; Carrondo, M.A.. "Spore-coat laccase CotA from Bacillus subtilis: Crystallization and preliminary X-ray characterization by the MAD method". Acta Crystallographica Section D: Biological Crystallography 58 9 (2002): 1490-1493. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036713444&partnerID=MN8TOARS.
    10.1107/S0907444902011575
  116. Frazão, C.; Enguita, F.J.; Coelho, R.; Sheldrick, G.M.; Navarro, J.A.; Hervás, M.; De la Rosa, M.A.; Carrondo, M.A.. "Crystal structure of low-potential cytochrome c549 from Synechocystis sp. PCC 6803 at 1.21 Å resolution". Journal of Biological Inorganic Chemistry 6 3 (2001): 324-332. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034855073&partnerID=MN8TOARS.
    10.1007/s007750100208
  117. Sousa, V.L.; Costa, M.T.; Palma, A.S.; Enguita, F.; Costa, J.. "Localization, purification and specificity of the full-length membrane-bound form of human recombinant a1,3/4-fucosyltransferase from BHK-21B cells". Biochemical Journal 357 3 (2001): 803-810. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035425330&partnerID=MN8TOARS.
    10.1042/0264-6021:3570803
  118. Leitão, A.L.; Enguita, F.J.; Martín, J.F.; Santos Oliveira, J.F.. "Effect of exogenous lysine on the expression of early cephamycin C biosynthetic genes and antibiotic production in Nocardia lactamdurans MA4213". Applied Microbiology and Biotechnology 56 5-6 (2001): 670-675. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034840439&partnerID=MN8TOARS.
    10.1007/s002530100715
  119. Enguita, F. J.; Frazao, C.; Coelho, R.; Navarro, J.; Hervas, M.; De la Rosa, M.; Sheldrick, G. M.; Carrondo, M. A.. "Ab initio crystal structure of low potential cytochrome c(549) from Synechocistis sp. PCC6803". Acta Crystallographica Section A: Foundations and Advances (2000): https://publons.com/publon/52924764/.
    10.1107/S0108767300025939
  120. Leitão AL; Enguita FJ; De La Fuente JL; Liras P; Martin JF; Leitão, A.L.; Enguita, F.J.; et al. "Inducing effect of diamines on transcription of the cephamycin C genes from the lat and pcbAB promoters in Nocardia lactamdurans.". Journal of bacteriology 181 8 (1999): 2379-2384. http://europepmc.org/abstract/med/10197999.
  121. Enguita FJ; Coque JJ; Liras P; Martin JF; Enguita, F.J.; Coque, J.J.R.; Liras, P.; Martin, J.F.. "The nine genes of the Nocardia lactamdurans cephamycin cluster are transcribed into large mRNAs from three promoters, two of them located in a bidirectional promoter region.". Journal of Bacteriology 180 20 (1998): 5489-5494. http://europepmc.org/abstract/med/9765587.
  122. Perez-Llarena, F.J.; Rodriguez-Garcia, A.; Enguita, F.J.; Martin, J.F.; Liras, P.; Pérez-Llarena FJ; Rodríguez-García A; et al. "The pcd gene encoding piperideine-6-carboxylate dehydrogenase involved in biosynthesis of a-aminoadipic acid is located in the cephamycin cluster of Streptomyces clavuligerus". Journal of Bacteriology 180 17 (1998): 4753-4756. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031751106&partnerID=MN8TOARS.
  123. Leitão, A.L.; Enguita, F.J.; Martín, J.F.. "Improved oxygen transfer in cultures of Nocardia lactamdurans maintains the cephamycin biosynthetic proteins for prolonged time and enhances the conversion of deacetylcephalosporin into cephamycin C". Journal of Biotechnology 58 1 (1997): 39-50. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031549639&partnerID=MN8TOARS.
    10.1016/S0168-1656(97)00129-6
  124. Enguita FJ; de la Fuente JL; Martín JF; Liras P; Enguita, F.J.; De La Fuente, J.L.; Martín, J.F.; Liras, P.. "An inducible expression system of histidine-tagged proteins in Streptomyces lividans for one-step purification by Ni2+ affinity chromatography.". FEMS microbiology letters 137 2-3 (1996): 135-140. http://europepmc.org/abstract/med/8998975.
    10.1111/j.1574-6968.1996.tb08095.x
  125. Coque, J.J.R.; Enguita, F.J.; Cardoza, R.E.; Martin, J.F.; Liras, P.; Coque JJ; Enguita FJ; et al. "Characterization of the cefF gene of Nocardia Lactamdurans encoding a 3'-methylcephem hydroxylase different from the 7-cephem hydroxylase". Applied Microbiology and Biotechnology 44 5 (1996): 605-609. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030019447&partnerID=MN8TOARS.
    10.1007/s002530050606
  126. Enguita, F.J.; Liras, P.; Leitão, A.L.; Martíne, J.F.. "Interaction of the two proteins of the methoxylation system involved in cephamycin C biosynthesis: Immunoaffinity, protein cross-linking, and fluorescence spectroscopy studies". Journal of Biological Chemistry 271 52 (1996): 33225-33230. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030465056&partnerID=MN8TOARS.
    10.1074/jbc.271.52.33225
  127. Leitão, A.L.; Enguita, F.J.; De La Fuente, J.L.; Liras, P.; Martín, J.F.. "Allophane increases the protein levels of several cephamycin biosynthetic enzymes in Nocardia lactamdurans". Microbiology 142 12 (1996): 3399-3406. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030470447&partnerID=MN8TOARS.
  128. Coque JJ; Enguita FJ; Martín JF; Liras P; Coque, J.J.R.; Enguita, F.J.; Martin, J.F.; Liras, P.. "A two-protein component 7 alpha-cephem-methoxylase encoded by two genes of the cephamycin C cluster converts cephalosporin C to 7-methoxycephalosporin C.". Journal of Bacteriology 177 8 (1995): 2230-2235. http://europepmc.org/abstract/med/7721717.
    10.1128/jb.177.8.2230-2235.1995
  129. Coque, J.J.R.; Perez-Llarena, F.J.; Enguita, F.J.; Fuente, J.L.; Martin, J.F.; Liras, P.. "Characterization of the cmcH genes of Nocardia lactamdurans and Streptomyces clavuligerus encoding a functional 3'-hydroxymethylcephem O-carbamoyltransferase for cephamycin biosynthesis". Gene 162 1 (1995): 21-27. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029126219&partnerID=MN8TOARS.
    10.1016/0378-1119(95)00308-S
Capítulo de livro
  1. Leitão, Ana L.; Costa, Marina C.; Gabriel, André F.; Enguita, Francisco J.. "Bioinformatics utilities, web resources and integrative strategies for the analysis of miRNA regulatory networks". 109-124. Elsevier, 2022.
    10.1016/b978-0-12-822287-4.00009-8
  2. Costa, Marina C.; Leitão, Ana L.; Gabriel, André F.; Enguita, Francisco J.. "Wet-lab methods for miRNA analysis". 93-107. Elsevier, 2022.
    10.1016/b978-0-12-822287-4.00008-6
  3. Costa, Marina C.; Gabriel, André F.; Enguita, Francisco J.. "Bioinformatics Research Methodology of Non-coding RNAs in Cardiovascular Diseases". In Advances in Experimental Medicine and Biology, 49-64. Singapura: Springer Singapore, 2020.
    Aceite para publicação • 10.1007/978-981-15-1671-9_2
  4. Gabriel, André F.; Costa, Marina C.; Enguita, Francisco J.. "Interactions Among Regulatory Non-coding RNAs Involved in Cardiovascular Diseases". In Advances in Experimental Medicine and Biology, 79-104. Springer Singapore, 2020.
    10.1007/978-981-15-1671-9_4
Livro
  1. Leitão, A.L.; Costa, M.C.; Enguita, F.J.. Human fungal infections: Emerging role of small non-coding RNAs as modulators of host-pathogen interactions. 2016.
    10.1007/978-3-319-39496-1_14
  2. Leitço, A.L.; Enguita, F.J.. Preface. 2016.
    10.1007/978-3-319-39496-1
  3. Enguita, F.J.; Leitão, A.L.. Hydroquinone: Properties and microbial degradation processes. 2014.
Poster em conferência
  1. Inteiro-Oliveira, Sara; Barreira-Fernandes, Lia; Costa-Coelho, Tiago; Ferreira-Manso, Mafalda; Sebastião, AM; Enguita, Francisco J.; Diógenes, MJ. "A virtual-aided design of small compounds to prevent BDNF receptor cleavage in Alzheimer’s disease". Trabalho apresentado em EPHAR2024, 2024.
  2. Gabriel, André F.; Cortez-Dias, Nuno; Enguita, Francisco J.; Costa, Marina C.. "Heartfelt Harmony: RBP and circRNA's cardiovascular Pas de Deux". Trabalho apresentado em EMBO Practical Course iCLIP2: An advanced technique for protein-RNA interaction mapping, 2024.
  3. Gabriel, André F.; Lopes, Catarina S.; Carvalho, A. Filomena; Vaz, Sandra H.; Santos, Nuno C.; Enguita, Francisco J.; Costa, Marina C.. "Circular RNAs in cardiovascular disease: Insights from a cardiac cell model". Trabalho apresentado em EMBO Workshop on The new cardiobiology, 2024.
  4. Gabriel, André F.; Lopes, Catarina S.; Carvalho, A. Filomena; Vaz, Sandra H.; Lourenço, Diogo M.; Santos, Nuno C.; Enguita, Francisco J.; Costa, Marina C.. "Into the Heart of Cardiac Diseases: Lessons from a Cardiac Model". Trabalho apresentado em 13th EMBO Young Scientists¿ Forum, 2023.
  5. Inteiro-Oliveira, Sara; Barreira-Fernandes, Lia; Costa-Coelho, Tiago; Ferreira-Manso, Mafalda; Sebastião, AM; Enguita, Francisco J.; Diógenes, MJ. "Small Compounds: a promising strategy to prevent TrkB-FL cleavage in Alzheimers Disease". Trabalho apresentado em EMBO Young Scientists Forum, 2023.
  6. Inteiro-Oliveira, Sara; Barreira-Fernandes, Lia; Costa-Coelho, Tiago; Ferreira-Manso, Mafalda; Sebastião, AM; Enguita, Francisco J.; Diógenes, MJ. "Small Compounds: a new promising strategy to prevent BDNF receptor cleavage". Trabalho apresentado em 37ª Reunião Anual Grupo de Estudos de Envelhecimento Cerebral e Demência, 2023.
  7. Gabriel, André F.; Costa, Marina C.; Cortez-Dias, Nuno; Enguita, Francisco J.. "The Battle for the Heartbeat: How circRNA-RBP Interactions Impact Atrial Fibrillation". Trabalho apresentado em RNA2023 Singapore (28th RNA Society annual meeting), 2023.
  8. Gabriel, André F.; Lopes, Catarina S.; Carvalho, A. Filomena; Vaz, Sandra H.; Santos, Nuno C.; Enguita, Francisco J.; Costa, Marina. "Sailing through the Surface to Unveil the Inner Workings of AC16 Cells: A Biophysical and Transcriptomic Expedition towards an Atrial Fibrillation cell model". Trabalho apresentado em XVI CAML · VI NeurULisboa PhD Students Meeting, 2023.
  9. Inteiro-Oliveira, Sara; Barreira-Fernandes, Lia; Costa-Coelho, Tiago; Ferreira-Manso, Mafalda; Sebastião, AM; Enguita, Francisco J.; Diógenes, MJ. "Computational-aided design of small compounds to prevent TrkB-FL receptor cleavage". Trabalho apresentado em FENS Regional Meeting 2023, 2023.
  10. Gabriel, André; Costa, Marina; Cortez-Dias, Nuno; Enguita, Francisco J.. "Predicting circRNA-RBP associations in Atrial Fibrillation". Trabalho apresentado em IX ptRNA: RNA in Disease, 2023.
  11. Inteiro-Oliveira, Sara; Costa-Coelho, Tiago; Ferreira-Manso, Mafalda; Sebastião, AM; Enguita, Francisco J.; Diógenes, MJ. "Virtual docking design of small compounds to prevent TrkB-FL receptor cleavage". Trabalho apresentado em 3rd Anual Meeting of Epileptogenesis and Epilepsy Network (EpiEpiNET), 2022.
  12. Barreira-Fernandes, Lia; Inteiro-Oliveira, Sara; Sebastião, AM; Enguita, Francisco J.; Diógenes, MJ. "Analyzing new compounds in attempt to prevent TrkB-FL receptor cleavage". Trabalho apresentado em 4. 3rd Anual Meeting of Epileptogenesis and Epilepsy Network (EpiEpiNET), 2022.
  13. Gabriel, André F.; Costa, Marina C.; Cortez-Dias, Nuno; Enguita, Francisco J.. "Towards a comprehensive characterization of the regulatory interactome between circRNAs and RNA binding proteins in Atrial Fibrillation". Trabalho apresentado em XV CAML · V NeurULisboa PhD Students Meeting,, 2022.
  14. Inteiro-Oliveira, Sara; Costa-Coelho, Tiago; Ferreira-Manso, Mafalda; Sebastião, AM; Enguita, Francisco J.; Diógenes, MJ. "Computer-aided drug design of small compounds to prevent TrkB-FL receptor cleavage". Trabalho apresentado em AIMS research competition, 2022.
  15. Inteiro-Oliveira, Sara; Costa-Coelho, Tiago; Ferreira-Manso, Mafalda; Sebastião, AM; Enguita, Francisco J.; Diógenes, MJ. "Screening of small, non-peptide compounds to prevent TrkB-FL cleavage in Alzheimer´s disease". Trabalho apresentado em Portuguese Society for Neuroscience (SPN), 2021.
  16. Inácio, Daniel; Amado, Tiago; Sobral, Daniel; Enguita, Francisco J.; Silva-Santos, Bruno; Gomes, AQ. "Uncovering the role of microRNAs in the control of effector gd T cell differentiation.". Trabalho apresentado em EMBL Symposium: The Non-Coding Genome, EMBL, 2019.
  17. Costa, Marina C.; Gabriel, André F.; Pinto, Fausto. J.; Cortez-Dias, Nuno; Enguita, Francisco J.. "Regulatory circRNA-centered networks and miRNA sponging activity in permanent atrial fibrillation". Trabalho apresentado em 3rd International Symposium on Frontiers in Molecular Science ¿ RNA Regulatory Networks, 2019.
  18. Gabriel, André; Aguiar, Patrício; Costa, Marina C.; Azevedo, Olga; Ducla Soares, José Luis; Hughes, Derralynn; Enguita, Francisco J.. "Circulating serum miRNAs as biomarkers in Fabry disease: adverse disease outcome and functional distinction between phenotypic groups". Trabalho apresentado em 3rd International Symposium on Frontiers in Molecular Science ¿ RNA Regulatory Networks, 2019.
  19. Inácio, D.; Amado, Tiago; Sobral, Daniel; Enguita, Francisco J.; Gomes, AQ; SILVA-SANTOS, Bruno. "A key role for microRNAs in regulating IL-17 versus IFN-g production by gd T cells.". Trabalho apresentado em The 3rd International Symposium on Frontiers in Molecular Science ¿ RNA Regulatory Networks, 2019.
  20. Amado, T; Schmolka, N.; Sobral, Daniel; Enguita, Francisco J.; Inácio, D.; SILVA-SANTOS, Bruno; Gomes, AQ. "A key role for microRNAs in regulating IL-17 versus IFN-g production by gamma-delta T cells". Trabalho apresentado em 5th European Congress of Immunology, 2018.
  21. Marques, Carla; Baptista, Rui ; Matafome, Paulo; Zuzarte, Mónica; Castro, Graça; Pereira, Paulo; Enguita, Francisco J.. "The significance in Pulmonary Arterial Hypertension of miR-424". Trabalho apresentado em 3rd PROTEOSTASIS Action Meeting: PROTEOSTASIS and its Biological Implications, 2017.
  22. Marques, Carla; Baptista, Rui ; Matafome, Paulo; Zuzarte, Mónica; Enguita, Francisco J.; Girão, Henrique. "miR-424 and SMURF1: the significance in Pulmonary Arterial Hypertension". Trabalho apresentado em Pt Beat, 2017.
Pré-impressão
  1. Giada Corti; JangKeun Kim; Francisco Enguita; Joseph Guarnieri; Lawrence Grossman; Sylvain Costes; Matias Fuentealba; et al. "To boldly go where no microRNAs have gone before: Spaceflight impact on risk for small-for-gestational-age infants". 2024. https://doi.org/10.21203/rs.3.rs-4003363/v1.
    10.21203/rs.3.rs-4003363/v1
  2. Filipa B. Gonçalves; Francisco J. Enguita; Vanessa A. Morais. "PINK1-G411S mutant increases kinase stability and enhances mitochondrial-linked functions". 2024. https://doi.org/10.1101/2024.06.28.601304.
    10.1101/2024.06.28.601304
  3. Pranujan Pathmendra; Yasunori Park; Francisco J. Enguita; Jennifer A. Byrne. "Verification of nucleotide sequence reagent identities in original publications in high impact factor cancer research journals". 2023. https://doi.org/10.1101/2023.02.03.526922.
    10.1101/2023.02.03.526922
  4. J. Tyson McDonald; Lily Farmerie; Meghan Johnson; Jiwoon Park; JangKeun Kim; Eliah Overbey; Jeffrey Haltom; et al. "So Long, and Thanks for All the Antagomirs: Space Radiation Damage Rescued by Inhibition of Key Spaceflight Associated miRNAs". 2023. https://doi.org/10.21203/rs.3.rs-2370597/v1.
    10.21203/rs.3.rs-2370597/v1
  5. Costa* M; Calderon-Dominguez* M; Mangas A; Campuzano O; Sarquella-Brugada G; Ramos M; Quezada-Feijoo M; et al. "Circulating circRNA as Biomarkers For Dilated Cardiomyopathy Etiology". 2021. http://europepmc.org/abstract/PPR/PPR299892.
    10.21203/rs.3.rs-298067/v1
Website
  1. Enguita, Francisco J.. miRNAtools3: utilities for miRNA analysis. 2016. https://mirnatools.eu.

Outros

Outra produção
  1. Genome-wide Associations of Flavivirus Capsid Proteins. 2019. Boon PL; Martins AS; Enguita FJ; Lim XN; Santos NC; Matsudaira PT; Martins IC; et al. http://europepmc.org/abstract/PPR/PPR76101.
    10.1101/606905
  2. miRNAtools: advanced training using the miRNA web of knowledge. 2017. Francisco J. Enguita.
    10.1101/170126
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2018/06/22 The non-coding RNAs panorama in cardiovascular diseases. I NoTes meeting, Novel therapeutic strategies for non-communicable diseases
Universidade do Porto (Porto, Portugal)
2017/11/07 ncRNAs in heart conditions: biomarkers and functional players Workshop on Noncoding RNA-mediated metabolic regulation in health and disease, Current trends in Biomedicine
Universidad Internacional de Andalucia (Baeza, Espanha)
2017/06/21 miRNAtools: advanced training using the miRNA web of knowledge 2nd International symposium on frontiers in molecular science: non-coding RNAs and epigenetics in cancer
University of Basel (Basel, Suiça)
2016/10/13 Expanding the functional role of miRNAs in the establishment of permanent atrial fibrillation XXI Symposium of the Polish Society for Experimental Cardiology
University of Warsaw (Rynia, Polónia)
2013/05/17 Non-coding transcriptome of human cell aging XIII Simpósio de Genética
UNESP (Botucatu, Brasil)
2012/08/25 Circulating microRNA: novel biomarkers for early prognostic stratification of acute myocardial infarction European Society of Cardiology Congress 2012
University of Munich (Munich, Alemanha)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2021/01 - Atual Unraveling the functional interactions between circular RNAs and RNA binding proteins in atrial fibrillation
Orientador de Andre Gabriel
Instituto de Medicina Molecular, Portugal
2016/01 - Atual e-FH. The role of epigenetics in Familial Hypercholesterolaemia phenotypes - towards a more precise medicine
Coorientador
Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
2015/01/01 - 2022/02/21 Physiopathological and diagnosis implications of miRNAs in cardiovascular diseases
Orientador
Universidade de Lisboa Faculdade de Medicina, Portugal
2015/01/01 - 2015/11/25 Bead-based microfluidic system for DNA/RNA detection
Coorientador
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012/01/01 - 2015/01/14 miRNA regulation of TAL1 transcription factor. Relationships with human leukaemias
Coorientador
Instituto de Medicina Molecular, Portugal
2014/01/01 - 2014/07/03 Electrokinetic and optical detection of nucleic acids for biomedical diagnosis in microfluidics
Coorientador
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013/01/01 - 2013/11/21 Detection of circulating miRNAs using microfluidics: a diagnosis method for cardiovascular diseases
Coorientador
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012/01/01 - 2012/11/16 Tratamento de dados de NGS para a pesquisa de novas mutações associadas à Miocardiopatia hipertrófica
Coorientador
Universidade de Lisboa Faculdade de Ciências, Portugal
2011/01/01 - 2011/11/22 In silico analysis of miRNA gene promoters
Orientador
Universidade de Lisboa Faculdade de Ciências, Portugal
2005/01/01 - 2010/10/08 Structural studies of two-component protein regulatory systems involved in phosphate control from Deinococcus radiodurans
Orientador
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

ESRF, França
2010/01/01 - 2010/07/23 miRNAs and aging
Orientador
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006/01/01 - 2010/05/14 Type III pili assembly mechanism in Klebsiella pneumoniae
Orientador
Birkbeck University of London, Reino Unido

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2004/01/01 - 2008/11/14 Structural studies on glycerol-metabolyzing enzymes in Klebsiella pneumoniae
Orientador
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2008 - 2008 Biochemical and Structural Studies on the Phor-phob Two-component Regulatory System from Deinococcus Radiodurans
Orientador
 Farmácia (Doutoramento)
Universidade de Lisboa, Portugal
2007/01/01 - 2007/09/13 Intermap3D: visualizing predicted interacting residues
Coorientador
Universidade de Lisboa Instituto Superior Técnico, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2024/03/12 - 2024/03/30 Participation as invited artist in a collective exhibition. Figure 1.A. Main exhibition 2024, Hôtel de Ville, Lausanne.
Exposição
 Main exhibition
Figure 1A, Suiça
2022/09/01 - 2022/09/30 Participation as invited artist in a collective exhibition. Figure 1.A. Main exhibition 2022, Hôtel de Ville, Lausanne.
Exposição
 Figure 1.A. Main exhibition 2022
Figure 1A, Suiça
Distinções

Prémio

2000 Premio Extraordinario de Doctorado
Universidad de Salamanca Facultad de Farmacia, Espanha
1992 Premio Extraordinario de Licenciatura
Universidad de Granada Facultad de Farmacia, Espanha