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Bárbara Albuquerque (BA) is a PhD student in the Doctoral Program of Experimental and Clinical Pharmacology and Toxicology at the Faculty of Medicine of the University of Porto (FMUP), in collaboration with the Abel Salazar Biomedical Sciences Institute (ICBAS) and the Faculty of Pharmacy of the University of Porto. She began her doctoral studies in 2024, building on a strong academic background, including a master’s degree in Biochemistry (2018-2023), completed with distinction, at the Faculty of Sciences of the University of Porto (FCUP) and ICBAS. Her research journey started in 2021 with a curricular internship at the Institute for Research and Innovation in Health, collaborating with the Glial Cell Biology Group and the LAQV/REQUIMTE group. This experience strengthened her interest in biomedical research and enhanced her skills in laboratory techniques, including in vitro studies and fluorescence microscopy, as well as teamwork. Later, BA conducted her master’s thesis at FMUP (Department of Biomedicine – Unit of Pharmacology and Therapeutics), in collaboration with the Research Center in Chemistry - Institute of Molecular Sciences at FCUP. Supervised by Professor Patrício Soares-da-Silva and Professor Fernanda Borges, she evaluated the pharmacological properties of novel Catechol-O-methyltransferase inhibitors. She conducted drug screening assays, pharmacodynamic and pharmacokinetic evaluations, and both in vitro and in vivo studies to assess the efficacy, safety, and bioavailability of the novel compounds. In recognition of her work, BA received a research fellowship in 2023-2024 from the Center for Drug Discovery and Innovative Medicines. During this period, she not only further developed her technical expertise but also enhanced several soft skills, such as technical writing, oral communication, project planning, data analysis, and collaboration with national research groups. Her contributions to the field have been substantial. BA has co-authored two original publications in prestigious Q1 scientific journals, demonstrating her commitment to high-quality research. Additionally, she is a co-inventor of a patent and has actively participated in various national congresses, presenting her findings and networking with experts in pharmacology and biomedical sciences. Her scientific work has been recognized with an award from U.Porto Innovation, underscoring her potential as a researcher. BA has also contributed to the academic community through her participation in the organization of the 55th Meeting of the Portuguese Society of Pharmacology, which aimed at fostering collaboration between students, researchers, and doctors in the field of pharmacology and toxicology, enriching her scientific perspective and broadening her professional network. BA has expanded her knowledge through complementary training, completing courses such as FELASA B and online courses in neuroscience, cellular biology, and immunology from international universities. Additionally, she volunteered as a mentor at the University of Porto, contributing to the academic and personal development of a student. Currently, she works as a researcher at RISE-Health (TL5 - Clinical Translation on Drug Targets and Innovative Biomedicines, Cell Signaling, Biomarkers, and New Drug Targets Group), where she is focused on drug screening for neuropsychiatric disorders. Bárbara's dedication, critical thinking, and collaborative spirit underscore her commitment to advancing biomedical research, making her a valuable contributor to the scientific community.
Identificação

Identificação pessoal

Nome completo
Bárbara Patrícia Varela Albuquerque

Nomes de citação

  • Albuquerque, Bárbara

Identificadores de autor

Ciência ID
BC13-0D63-D92E
ORCID iD
0009-0005-7505-9802

Endereços de correio eletrónico

  • up201804981@up.pt (Profissional)
  • barbaravarelalbuquerque@hotmail.com (Pessoal)

Telefones

Telemóvel
  • 963674970 (Pessoal)

Moradas

  • Professor Hernâni Monteiro Avenue, 4200-319, Porto, Porto, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia
  • Ciências Exatas - Química
  • Ciências Naturais - Ciências Biológicas - Métodos de Investigação Bioquímica
  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C2)
Inglês Utilizador independente (B1)
Formação
Grau Classificação
2024/02/09 - 2028
Em curso
Doctoral Program in Experimental and Clinical Pharmacology and Toxicology (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
2025/02 - 2025/02
Concluído
FELASA B - Curso em Ciências de Animais de Laboratório (Outros)
Universidade do Porto Faculdade de Medicina, Portugal
2021/09 - 2023/11/17
Concluído
Master's Degree in Biochemistry (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Pharmacodynamic evaluation of novel Catechol-O-methyltransferase inhibitors" (TESE/DISSERTAÇÃO)
17
2021/09 - 2021/09
Concluído
Cannabis, Mental Health, and Brain Disorders - Coursera (Outros)
University of Colorado at Boulder, Estados Unidos
2021/08 - 2021/08
Concluído
Introduction to the Biology of Cancer - Coursera (Outros)
The Johns Hopkins University School of Medicine, Estados Unidos
2021/07 - 2021/07
Concluído
Fundamentals of Immunology: Death by Friendly Fire - Coursera (Outros)
Rice University, Estados Unidos
2018/09 - 2021/07
Concluído
Degree in Biochemistry (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Evaluation of the antioxidant and neuroprotective properties of Tryptophyllin PpT-2" (TESE/DISSERTAÇÃO)
16
2021/02 - 2021/02
Concluído
Fundamental Neuroscience for Neuroimaging - Coursera (Outros)
The Johns Hopkins University School of Medicine, Estados Unidos
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2024/09 - Atual Investigador (Investigação) Rise-Health, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2023/01 - 2025/01 Investigador (Investigação) Universidade do Porto Centro de Investigação Farmacológica e Inovação Medicamentosa, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
(...)

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2021/02 - 2021/07 Curricular Internship Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
(...)
Produções

Publicações

Artigo em revista
  1. Benfeito, Sofia; Albuquerque, Bárbara; Sequeira, Lisa; Lima, Carla; Chavarria, Daniel; Serrão, Paula; Cagide, Fernando; Soares-da-Silva, Patrício; Borges, Fernanda. "Discovery of a Potent, Selective, and Blood-Brain Barrier Permeable Non-nitrocatechol Inhibitor of Catechol-O-methyltransferase". Journal of Medicinal Chemistry (2024): http://dx.doi.org/10.1021/acs.jmedchem.4c01682.
    10.1021/acs.jmedchem.4c01682
  2. Pinto, Miguel; Silva, Tiago Barros; Sardão, Vilma A.; Simões, Rui; Albuquerque, Bárbara; Oliveira, Paulo J.; Valente, Maria João; et al. "Cellular and Mitochondrial Toxicity of Tolcapone, Entacapone, and New Nitrocatechol Derivatives". ACS Pharmacology & Translational Science 7 5 (2024): 1637-1649. http://dx.doi.org/10.1021/acsptsci.4c00124.
    10.1021/acsptsci.4c00124
Poster em conferência
  1. Albuquerque, Bárbara. "Pharmacodynamic evaluation of novel Catechol-O-methyltransferase inhibitors". Trabalho apresentado em IJUP, 2023.
Resumo em conferência
  1. Albuquerque, Bárbara. "Mitochondrial evaluation of a novel Catechol-O-methyltransferase inhibitor". Trabalho apresentado em 55th Meeting of Portuguese Society of Pharmacology, Porto, 2025.
    Submetido
  2. Albuquerque, Bárbara. "Pharmacodynamic evaluation of novel Catechol-O-methyltransferase inhibitors". Trabalho apresentado em 54th Meeting of the Portuguese Society of Pharmacology, Lisbon, 2024.
Tese / Dissertação
  1. "Pharmacodynamic evaluation of novel Catechol-O-methyltransferase inhibitors". Mestrado, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 2023.

Propriedade Intelectual

Pedido provisório de patente
  1. 2024. "Novel catechol-O-methyltransferase inhibitors, methods for preparation and use thereof".
    Protegido
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2025/02/07 Mitochondrial evaluation of a novel Catechol-O-methyltransferase inhibitor 55th Meeting of Portuguese Society of Pharmacology
Faculty of Medicine of the University of Porto (Porto, Portugal)
2024/02/08 Pharmacodynamic evaluation of novel Catechol-O-methyltransferase inhibitors 54th Meeting of the Portuguese Society of Pharmacology
NOVA Medical School (Lisboa, Portugal)
2023/06 Pharmacodynamic evaluation of novel Catechol-O-methyltransferase inhibitors Young research meeting at the University of Porto
Reitory of the University of Porto (Porto, Portugal)

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2025/02/05 - 2025/02/07 55th Meeting of Portuguese Society of Pharmacology (2025/02/05 - 2025/02/07)
Congresso (Outra)

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2025/02/05 - 2025/02/07 55th Meeting of Portuguese Society of Pharmacology
Congresso
55th Meeting of Portuguese Society of Pharmacology
Universidade do Porto Faculdade de Medicina, Portugal
2024/02/07 - 2024/02/09 54th Meeting of the Portuguese Society of Pharmacology
Congresso
54th Meeting of the Portuguese Society of Pharmacology
Universidade Nova de Lisboa Medical School, Portugal
2022/04 - 2022/04 VMD Workshop
Oficina (workshop)
Formação VMD - Biochemistry students' group of University of Porto
Universidade do Porto, Portugal
2022/04 - 2022/04 VII Biochemistry Journeys: - Workshop In search of protein - Workshop Bloodstain pattern analysis - Workshop Humanized yeasts as a model organism in biomedicine - Workshop Food chemistry -
Oficina (workshop)
VII Biochemistry Journeys - Biochemistry student' group of University of Porto
Universidade do Porto, Portugal
2021/05 - 2021/05 VI Biochemistry Journeys: - Workshop Cell culture bases - Workshop Immunohistochemistry - Workshop Hands on: Molecular Biology
Oficina (workshop)
VI Biochemistry Journeys - Biochemistry student' group of University of Porto
Universidade do Porto, Portugal
2021/03 - 2021/03 Brain Gain: discovering Neurosciences
Seminário
Brain Gain: discovering Neurosciences - Center for Neuroscience and Cell Biology
Universidade de Coimbra, Portugal
2021/03 - 2021/03 Science and Research - EU Careers Fair EU Careers Portugal
Seminário
Science and Research - EU Careers Fair
2021/03 - 2021/03 Training week: - Workshop Endnote and databases - Workshop Microsoft Excel - Workshop Communication and scientific writing
Oficina (workshop)
Training week - Student association of the Faculty of Sciences of the University of Porto
Universidade do Porto Faculdade de Ciências, Portugal
2020/05 - 2020/05 Workshop Oral communication in science
Oficina (workshop)
Workshop Oral communication in science - Speak & Lead
2020/01 - 2020/01 Young research meeting at the University of Porto
Conferência
Young research meeting at the University of Porto
Universidade do Porto, Portugal
2019/03 - 2019/03 XII National meeting of Biochemistry' students
Conferência
XII National meeting of Biochemistry' students
Universidade de Aveiro, Portugal
2019/01 - 2019/01 Young research meeting at the University of Porto
Conferência
Young research meeting at the University of Porto
Universidade do Porto, Portugal

Membro de associação

Nome da associação Tipo de participação
2024/02 - Atual Portuguese Society of Pharmacology Student Member

Tutoria

Tópico Nome do aluno
2021/09 - 2022/07 Mentorship - University of Porto Inês Alves Costa
Distinções

Prémio

2024 BIP Proof