| Artigo em revista |
- Franco Machado, João; Sá, Marco; Pires, Inês; da Silva, Miguel Tarita; Marques, Fernanda; Jaime A. S. Coelho; Mendes, Filipa;
et al. "Dual FGFR-targeting and pH-activatable ruthenium–peptide conjugates for targeted therapy of breast cancer". Dalton
Transactions (2024): http://dx.doi.org/10.1039/d4dt00497c.
Acesso aberto • Publicado • 10.1039/d4dt00497c
- Schauenburg, Dominik; Gao, Bingjie; Rochet, Léa N. C.; Schüler, Darijan; Jaime A. S. Coelho; Ng, David Y. W.; Chudasama, Vijay;
Kuan, Seah Ling; Weil, Tanja. "Macrocyclic Dual-Locked "Turn-On" Drug for Selective and Traceless Release in Cancer Cells".
Angewandte Chemie International Edition (2024): http://dx.doi.org/10.1002/anie.202314143.
Acesso aberto • Publicado • 10.1002/anie.202314143
- Andrade, Késsia H. S.; Jaime A. S. Coelho; Frade, Raquel; Madureira, Ana M.; Nunes, João P. M.; Caddick, Stephen; Gomes, Rafael
F. A.; Afonso, Carlos A. M.. "Functionalized Cyclopentenones with Low Electrophilic Character as Anticancer Agents". ChemMedChem
18 13 (2023): http://dx.doi.org/10.1002/cmdc.202300104.
Acesso aberto • Publicado • 10.1002/cmdc.202300104
- Clemente, Duarte B.; Coelho, Jaime A. S.*. Autor correspondente: Coelho, Jaime A. S.*. "A Historical Review of the Total Synthesis
of Natural Products Developed in Portugal". European Journal of Organic Chemistry (2023): http://dx.doi.org/10.1002/ejoc.202300193.
Acesso aberto • Publicado • 10.1002/ejoc.202300193
- Cavaca, Lídia A. S.; Jaime A. S. Coelho; Lucas, Susana D.; Loureiro, Rui M. S.; Gomes, Rafael F. A.; Afonso, Carlos A. M..
"Upgrading furanic platforms to a-enaminones: tunable continuous flow hydrogenation of bio-based cyclopentenones". Reaction
Chemistry & Engineering 8 2 (2023): 482-489. http://dx.doi.org/10.1039/d2re00292b.
Acesso aberto • Publicado • 10.1039/d2re00292b
- João Macara; Catarina Caldeira; José Cunha; Jaime A. S. Coelho; Maria J. S. A. Silva; Konrad Krämer; Christoph W. Grathwol;
Stefan Bräse; M. Manuel B. Marques. "Practical synthesis and biological screening of sulfonyl hydrazides". Organic & Biomolecular
Chemistry (2023): https://doi.org/10.1039/D2OB02160A.
Publicado • 10.1039/D2OB02160A
- Wu, Yingke; Balasubramanian, Priyadharshini; Wang, Zhenyu; Coelho, Jaime A. S.; Prslja, Mateja; Siebert, Reiner; Plenio, Martin
B.; Jelezko, Fedor; Weil, Tanja. "Detection of Few Hydrogen Peroxide Molecules Using Self-Reporting Fluorescent Nanodiamond
Quantum Sensors". Journal of the American Chemical Society 144 28 (2022): 12642-12651. http://dx.doi.org/10.1021/jacs.2c01065.
Acesso aberto • Publicado • 10.1021/jacs.2c01065
- A. Gomes, Rafael F.; Ravasco, Joao M. J. M.; Andrade, Késsia H. S.; Coelho, Jaime A. S.; Moreira, Rui; Oliveira, Rafael; Nogueira,
Fátima; Afonso, Carlos A. M.. "Tandem Thio-Michael Addition/Remote Lactone Activation of 5-Hydroxymethylfurfural-Derived d-Lactone-Fused
Cyclopentenones". ChemSusChem (2022): http://dx.doi.org/10.1002/cssc.202102204.
Acesso aberto • Publicado • 10.1002/cssc.202102204
- Poeira, Diogo L.; Negrão, Ana Cláudia R.; Faustino, Hélio; Jaime A. S. Coelho; Gomes, Clara S. B.; Gois, Pedro M. P.; Marques,
M. Manuel B.. "Hypervalent Iodine(III) Reagents with Transferable Primary Amines: Structure and Reactivity on the Electrophilic
a-Amination of Stabilized Enolates". Organic Letters 24 2 (2022): 776-781. http://dx.doi.org/10.1021/acs.orglett.1c04312.
Publicado • 10.1021/acs.orglett.1c04312
- Zegota, Maksymilian Marek; Müller, Michael Andreas; Lantzberg, Bellinda; Kizilsavas, Gönül; Coelho, Jaime A. S.; Moscariello,
Pierpaolo; Martínez-Negro, María; et al. "Dual Stimuli-Responsive Dynamic Covalent Peptide Tags: Toward Sequence-Controlled
Release in Tumor-like Microenvironments". Journal of the American Chemical Society 143 41 (2021): 17047-17058. http://dx.doi.org/10.1021/jacs.1c06559.
Acesso aberto • Publicado • 10.1021/jacs.1c06559
- Marques, M. Manuel B.; Macara, João; Poeira, Diogo L.; Jaime A. S. Coelho. "PEG-Supported Hypervalent Iodine Reagent for Sulfonamide
Synthesis". Synlett 32 17 (2021): 1730-1734. http://dx.doi.org/10.1055/s-0040-1719828.
Publicado • 10.1055/s-0040-1719828
- Amado, Patrícia S. M.; Frija, Luís M. T.; Coelho, Jaime A. S.; O’Neill, Paul M.; Cristiano, Maria L. S.. "Synthesis of Non-symmetrical
Dispiro-1,2,4,5-Tetraoxanes and Dispiro-1,2,4-Trioxanes Catalyzed by Silica Sulfuric Acid". The Journal of Organic Chemistry
86 15 (2021): 10608-10620. http://dx.doi.org/10.1021/acs.joc.1c01258.
Publicado • 10.1021/acs.joc.1c01258
- Maria J. S. A. Silva; Hélio Faustino; Jaime A. S. Coelho; Maria V. Pinto; Adelaide Fernandes; Ismael Compañón; Francisco Corzana;
Gilles Gasser; Pedro M. P. Gois. "Efficient Amino-Sulfhydryl Stapling on Peptides and Proteins Using Bifunctional NHS-Activated
Acrylamides". Angewandte Chemie 133 19 (2021): 10945-10952. https://doi.org/10.1002/ange.202016936.
Publicado • 10.1002/ange.202016936
- Celso Martins; Diego O. Hartmann; Adélia Varela; Jaime A. S. Coelho; Pedro Lamosa; Carlos A. M. Afonso; Cristina Silva Pereira.
"Securing a furan-based biorefinery: disclosing the genetic basis of the degradation of hydroxymethylfurfural and its derivatives
in the model fungus Aspergillus nidulans". Microbial Biotechnology 13 6 (2020): 1983-1996. https://doi.org/10.1111/1751-7915.13649.
Acesso aberto • Publicado • 10.1111/1751-7915.13649
- Ravasco, Joao M. J. M.+; Coelho, Jaime A. S.+*. Autor correspondente: Coelho, Jaime A. S.+*. "Predictive Multivariate Models
for Bioorthogonal Inverse-Electron Demand Diels-Alder Reactions". Journal of the American Chemical Society (2020):
http://dx.doi.org/10.1021/jacs.9b11948.
Publicado • 10.1021/jacs.9b11948
- Ravasco, João M. J. M.; Coelho, Jaime A. S.; Trindade, Alexandre F.; Afonso, Carlos A. M.. "Synthesis and reactivity/stability
study of double-functionalizable strained trans-cyclooctenes for tetrazine bioorthogonal reactions". Pure and Applied Chemistry
92 1 (2020): 15-23. http://dx.doi.org/10.1515/pac-2019-0201.
Publicado • 10.1515/pac-2019-0201
- Huang, Banruo; He, Ying; Levin, Mark D.; Coelho, Jaime A. S.; Bergman, Robert G.; Toste, F. Dean. "Enantioselective Kinetic
Resolution/Desymmetrization of para-Quinols: A Case Study in Boronic-Acid-Directed Phosphoric Acid Catalysis". Advanced
Synthesis & Catalysis 362 2 (2019): 295-301. http://dx.doi.org/10.1002/adsc.201900816.
Publicado • 10.1002/adsc.201900816
- Marco Hebel; Andreas Riegger; Maksymilian M. Zegota; Gönül Kizilsavas; Jasmina Gacanin; Michaela Pieszka; Thorsten Lückerath;
et al. "Sequence Programming with Dynamic Boronic Acid/Catechol Binary Codes". Journal of the American Chemical Society
141, 36 (2019): 14026-14031. https://doi.org/10.1021/jacs.9b03107.
Acesso aberto • Publicado • 10.1021/jacs.9b03107
- Martins, Inês S.; Coelho, Jaime A. S.*. Autor correspondente: Coelho, Jaime A. S.*. "Solvent-Free Synthesis of 2,5Bis((dimethylamino)methylene)cyclopentanone".
Methods and Protocols 2 3 (2019): 69. http://dx.doi.org/10.3390/mps2030069.
Acesso aberto • Publicado • 10.3390/mps2030069
- Poeira, Diogo L.; Macara, João; Faustino, Hélio; Coelho, Jaime A. S.; Gois, Pedro M. P.; Marques, M. Manuel B.. "Hypervalent
Iodine Mediated Sulfonamide Synthesis". European Journal of Organic Chemistry 2019 15 (2019): 2695-2701. http://dx.doi.org/10.1002/ejoc.201900259.
Publicado • 10.1002/ejoc.201900259
- Rafael F. A. Gomes+; Jaime A. S. Coelho*+; Carlos A. M. Afonso*. Autor correspondente: Jaime A. S. Coelho*+. "Direct Conversion
of Activated 5-Hydroxymethylfurfural into d-Lactone-Fused Cyclopentenones". ChemSusChem 12 2 (2019): 420-425. https://doi.org/10.1002/cssc.201802537.
Publicado • 10.1002/cssc.201802537
- Gomes, Rafael F. A.; Coelho, Jaime A. S.*; Afonso, Carlos A. M.*. Autor correspondente: Coelho, Jaime A. S.*. "Synthesis and
Applications of Stenhouse Salts and Derivatives". Chemistry - A European Journal 24 37 (2018): 9170-9186. http://dx.doi.org/10.1002/chem.201705851.
Publicado • 10.1002/chem.201705851
- Zhu, Yi; Han, Jianlin; Wang, Jiandong; Shibata, Norio; Sodeoka, Mikiko; Soloshonok, Vadim A.; Coelho, Jaime A. S.; Toste,
F. Dean. "Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges
and Pharmaceutical Needs". Chemical Reviews 118 7 (2018): 3887-3964. http://dx.doi.org/10.1021/acs.chemrev.7b00778.
Publicado • 10.1021/acs.chemrev.7b00778
- Gomes, Rafael F. A.; Nuno R. Esteves; Jaime A. S. Coelho*; Carlos A. M. Afonso*. Autor correspondente: Jaime A. S. Coelho*.
"Copper(II) Triflate As a Reusable Catalyst for the Synthesis of trans-4,5-Diamino-cyclopent-2-enones in Water". The Journal
of Organic Chemistry 83 14 (2018): 7509-7513. http://dx.doi.org/10.1021/acs.joc.7b02931.
Publicado • 10.1021/acs.joc.7b02931
- Coelho, Jaime A. S.; Matsumoto, Akira; Orlandi, Manuel; Hilton, Margaret J.; Sigman, Matthew S.; Toste, F. Dean. "Enantioselective
fluorination of homoallylic alcohols enabled by the tuning of non-covalent interactions". Chemical Science 9 35 (2018):
7153-7158. http://dx.doi.org/10.1039/c8sc02223b.
Publicado • 10.1039/c8sc02223b
- Cavaca, L.A.S.; Rodrigues, C.A.B.; Simeonov, S.P.; Gomes, R.F.A.; Coelho, J.A.S.; Romanelli, G.P.; Sathicq, A.G.; Martínez,
J.J.; Afonso, C.A.M.. "Valorization of Oleuropein via Tunable Acid-Promoted Methanolysis". ChemSusChem 11 14 (2018):
2300-2305. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050403119&partnerID=MN8TOARS.
Publicado • 10.1002/cssc.201800980
- Vicente, Ana; Coelho, Jaime A. S.; Simeonov, Svilen; Lazarova, Hristina; Popova, Margarita; Afonso, Carlos. "Oxidation of
5-Chloromethylfurfural (CMF) to 2,5-Diformylfuran (DFF)". Molecules 22 2 (2017): 329. http://dx.doi.org/10.3390/molecules22020329.
Publicado • 10.3390/molecules22020329
- Joao M. J. M. Ravasco; Jaime A. S. Coelho; Svilen P. Simeonov; Carlos A. M. Afonso. "Bifunctional Cr3+ modified ion exchange
resins as efficient reusable catalysts for the production and isolation of 5-hydroxymethylfurfural from glucose". RSC Advances
7 13 (2017): 7555-7559. https://doi.org/10.1039/C6RA22539J.
Publicado • 10.1039/C6RA22539J
- Orlandi, M.; Coelho, J.A.S.; Hilton, M.J.; Toste, F.D.; Sigman, M.S.. "Parametrization of Non-covalent Interactions for Transition
State Interrogation Applied to Asymmetric Catalysis". Journal of the American Chemical Society 139 20 (2017): 6803-6806.
http://www.scopus.com/inward/record.url?eid=2-s2.0-85019657053&partnerID=MN8TOARS.
Publicado • 10.1021/jacs.7b02311
- Simeonov, Svilen; Coelho, Jaime A. S.; Afonso, Carlos A. M.. "Synthesis of 5-(Hydroxymethyl)furfural (HMF)". Organic Syntheses
93 (2016): 29-36. http://dx.doi.org/10.15227/orgsyn.093.0029.
Publicado • 10.15227/orgsyn.093.0029
- Ventura, Sónia P. M.; de Morais, Paulo; Coelho, Jaime A. S.; Sintra, Tânia; Coutinho, João A. P.; Afonso, Carlos A. M.. "Evaluating
the toxicity of biomass derived platform chemicals". Green Chemistry 18 17 (2016): 4733-4742. http://dx.doi.org/10.1039/c6gc01211f.
Publicado • 10.1039/c6gc01211f
- Gomes, Rafael F. A.; Coelho, Jaime A. S.*; Frade, Raquel F. M.; Trindade, Alexandre F.; Afonso, Carlos A. M.*. Autor correspondente:
Coelho, Jaime A. S.*. "Synthesis of Symmetric Bis(N-alkylaniline)triarylmethanes via Friedel–Crafts-Catalyzed Reaction between
Secondary Anilines and Aldehydes". The Journal of Organic Chemistry 80 20 (2015): 10404-10411. http://dx.doi.org/10.1021/acs.joc.5b01875.
Publicado • 10.1021/acs.joc.5b01875
- António, João P. M.; Frade, Raquel F. M.; Santos, Fábio M. F.; Coelho, Jaime A. S.; Afonso, Carlos A. M.; Gois, Pedro M. P.;
Trindade, Alexandre F.. "NHC catalysed direct addition of HMF to diazo compounds: synthesis of acyl hydrazones with antitumor
activity". RSC Adv. 4 55 (2014): 29352-29356. http://dx.doi.org/10.1039/c4ra03710c.
Publicado • 10.1039/c4ra03710c
- Coelho, Jaime A. S.; Trindade, Alexandre F.; André, Vânia; Teresa Duarte, M.; Veiros, Luis F.; Afonso, Carlos A. M.. "Trienamines
derived from 5-substituted furfurals: remote e-functionalization of 2,4-dienals". Org. Biomol. Chem. 12 46 (2014):
9324-9328. http://dx.doi.org/10.1039/c4ob01759e.
Publicado • 10.1039/c4ob01759e
- Frade, R. F. M.; Coelho, J. A. S.; Simeonov, S. P.; Afonso, C. A. M.. "An emerging platform from renewable resources: selection
guidelines for human exposure of furfural-related compounds". Toxicol. Res. 3 5 (2014): 311-314. http://dx.doi.org/10.1039/c4tx00019f.
Publicado • 10.1039/c4tx00019f
- Coelho, Jaime A. S.; Trindade, Alexandre F.; Wanke, Riccardo; Rocha, Bruno G. M.; Veiros, Luis F.; Gois, Pedro M. P.; Pombeiro,
Armando J. L.; Afonso, Carlos A. M.. "N-Heterocyclic Carbene Dirhodium(II) Complexes as Catalysts for Allylic and Benzylic
Oxidations". European Journal of Organic Chemistry 2013 8 (2013): 1471-1478. http://dx.doi.org/10.1002/ejoc.201201300.
Publicado • 10.1002/ejoc.201201300
- Simeonov, S.P.; Coelho, J.A.S.; Afonso, C.A.M.. "Integrated chemo-enzymatic production of 5-hydroxymethylfurfural from glucose".
ChemSusChem 6 6 (2013): 997-1000. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878622602&partnerID=MN8TOARS.
Publicado • 10.1002/cssc.201300176
- Trindade, Alexandre F.; Coelho, Jaime A. S.; Afonso, Carlos A. M.; Veiros, Luis F.; Gois, Pedro M. P.. "Fine Tuning of Dirhodium(II)
Complexes: Exploring the Axial Modification". ACS Catalysis 2 3 (2012): 370-383. http://dx.doi.org/10.1021/cs200597a.
Publicado • 10.1021/cs200597a
- Simeonov, S.P.; Coelho, J.A.S.; Afonso, C.A.M.. "An integrated approach for the production and isolation of 5-hydroxymethylfurfural
from carbohydrates". ChemSusChem 5 8 (2012): 1388-1391. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864699780&partnerID=MN8TOARS.
Publicado • 10.1002/cssc.201200236
- Kirillov, Alexander M.; Coelho, Jaime A. S.; Kirillova, Marina V.; Nesterov, Dmytro S.; Gruenwald, Katrin R.; Haukka, Matti;
Pombeiro, Armando J. L.. "Bringing an “Old” Biological Buffer to Coordination Chemistry: New 1D and 3D Coordination Polymers
with [Cu4(Hbes)4] Cores for Mild Hydrocarboxylation of Alkanes". Inorganic Chemistry 49 14 (2010): 6390-6392. http://dx.doi.org/10.1021/ic1007999.
Publicado • 10.1021/ic1007999
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