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Carla Carvalho obtained her degree in Biomedical Sciences in 2016 at the University of Aveiro. In 2018, she completed her MSc degree in Applied Biochemistry, with a specialisation in Biomedicine at the University of Minho. Until 2020, she worked on the project "Pre-clinical evaluation of optimized Miltefosine derivatives for the treatment of leishmaniasis and sleeping sickness" at the i3s institute. Currently, she is a research fellow at 3DUnit, under the supervision of Lucilia Saraiva.
Identificação

Identificação pessoal

Nome completo
Carla Sofia Costa Carvalho

Nomes de citação

  • Carvalho, Carla

Identificadores de autor

Ciência ID
F01B-ED97-E0D3
ORCID iD
0000-0003-1844-071X

Telefones

Telemóvel
  • 932348782 (Pessoal)

Moradas

  • Rua Santa Eulália, 4775-191, Negreiros, Barcelos, Portugal (Pessoal)

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2016/09 - 2018/12
Concluído
 Applied Biochemistry (Mestrado)
Especialização em Biomedicine
Universidade do Minho, Portugal
"Novel yeast biosensors for environmental monitoring" (TESE/DISSERTAÇÃO)
 18
2013/09 - 2016/07
Concluído
 Biomedical Sciences (Licenciatura)
Universidade de Aveiro, Portugal
 15
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2021/06/01 - 2021/12/31 Estagiário de Investigação (Investigação) Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2019/03 - 2020/08 Investigador (Investigação) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Projetos

Bolsa

Designação Financiadores
2019/03/01 - 2020/08/31 Pre-clinical evaluation of Miltefosine derivatives optimized for treatment of Leishmaniasis and Sleeping Sickness
POCI-01-0145-FEDER-031013
Bolseiro de Investigação
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
Em curso
Produções

Publicações

Artigo em revista
  1. Carvalho, Ana; Domingues, Inês; Carvalho, Carla; Silva, Artur M. S.; Soares, Amadeu M. V. M.; Marques, Catarina R.. "In Vitro Antiprotozoal Activity of Hibiscus sabdariffa Extract against a Ciliate Causing High Mortalities in Turbot Aquaculture". Biology 12 7 (2023): 912. http://dx.doi.org/10.3390/biology12070912.
    10.3390/biology12070912
  2. Long, Solida; Duarte, Denise; Carvalho, Carla; Oliveira, Rafael; Santarém, Nuno; Palmeira, Andreia; Resende, Diana I. S. P.; et al. "Indole-Containing Pyrazino[2,1-b]quinazoline-3,6-diones Active against Plasmodium and Trypanosomatids". ACS Medicinal Chemistry Letters 13 2 (2022): 225-235. http://dx.doi.org/10.1021/acsmedchemlett.1c00589.
    10.1021/acsmedchemlett.1c00589
  3. Loureiro, Joana B.; Raimundo, Liliana; Calheiros, Juliana; Carvalho, Carla; Barcherini, Valentina; Lima, Nuno R.; Gomes, Célia; et al. "Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance". Cancers 13 7 (2021): 1648. http://dx.doi.org/10.3390/cancers13071648.
    Publicado • 10.3390/cancers13071648
  4. Long, Solida; Loureiro, Joana B.; Carvalho, Carla; Gales, Luís; Saraiva, Lucília; Pinto, Madalena M. M.; Puthongking, Ploenthip; Sousa, Emília. "Semi-Synthesis of Small Molecules of Aminocarbazoles: Tumor Growth Inhibition and Potential Impact on p53". Molecules 26 6 (2021): 1637. http://dx.doi.org/10.3390/molecules26061637.
    Publicado • 10.3390/molecules26061637
  5. Barroso, Carolina; Carvalho, Pedro; Carvalho, Carla; Santarém, Nuno; Gonçalves, José F. M.; Rodrigues, Pedro N. S.; Neves, João V.. "The Diverse Piscidin Repertoire of the European Sea Bass (Dicentrarchus labrax): Molecular Characterization and Antimicrobial Activities". International Journal of Molecular Sciences 21 13 (2020): 4613. http://dx.doi.org/10.3390/ijms21134613.
    Publicado • 10.3390/ijms21134613
Poster em conferência
  1. Carvalho, Carla; Santarém, Nuno; Cordeiro-da-Silva, Anabela. "New promising molecules in drug development for Leishmaniasis.". Trabalho apresentado em DAY OF THE MICROBIOLOGY LABORATORY: Microbiology, Immunology and Oncobiology: Interdisciplinary approaches to control infectious diseases and cancer, 2019.
  2. Carvalho, Carla; Sousa, Maria João; Castro, Bruno Branco; Chaves, Susana. "Yeast system to uncover molecular targets of fungicides of environmental concern". Trabalho apresentado em IV Symposium of the Doctoral Program in Molecular and Environmental Biology, 2018.
  3. Carvalho, Carla; Sousa, Maria João; Castro, Bruno Branco; Chaves, Susana. "Saccharomyces cerevisiae as a model system to uncover target and off-target effects of fungicides of environmental concern". Trabalho apresentado em XXI Jornadas de Biologia de Leveduras "Professor Nicolau van Uden", 2018.
Tese / Dissertação
  1. Carvalho, Carla. "Novel yeast biosensors for environmental monitoring". Mestrado, Universidade do Minho Escola de Ciências, 2018. http://hdl.handle.net/1822/61738.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2021/02 Participation, as co-author, with the presentation "A xanthone with anticancer activity by potential inhibition of homologous recombination DNA repair in breast and ovarian cancer" in scientific meetings 51st Meeting of the Portuguese Society of Pharmacology in conjunction with the 39th Meeting of Clinical Pharmacology e 20th Meeting of Toxicology
Portuguese Society of Pharmacology (Lisboa, Portugal)
2021/02 Participation, as co-author, with the presentation "SLMP53-2: Promising anti-tumor activity in melanoma by targeting p53" in scientific meetings 51st Meeting of the Portuguese Society of Pharmacology in conjunction with the 39th Meeting of Clinical Pharmacology e 20th Meeting of Toxicology
Portuguese Society of Pharmacology (Lisboa, Portugal)
2021 Participation, as co-author, with the presentation "BP-C4 analogues with improved growth inhibitory activity: synthesis and biological activity evaluation" at the SIFFUP Symposium of the Pharmacy Faculty of the University of Porto (SIFFUP)
(Porto, Portugal)
2020/11 Participation, as co-author, with the presentation "SLMP53-1 inhibits tumor cell growth through regulation of glucose metabolism and angiogenesis in a p53-dependent manner" in an International Electronic Conference 6th International Electronic Conference on Medicinal Chemistry
Sciforum
2016/10/13 Participation in the Angelini University Award! 2015/2016, with the theme: "Products/Services/Social projects for cancer patients in palliative care" with the project " Resource management in PC- Idealization of a pilot platform" Angelini University Award! 2015/2016
Angelini Pharma (Lisboa, Portugal)

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2017/02/01 - 2017/05/31 Participation as a member of the Organizing Committee of the "I Simpósio em Bioquímica Aplicada" at University of Minho, aiming to explore the role of biochemistry in research and industry. " (2017/05/31 - 2017/05/31)
Simpósio (Membro da Comissão Organizadora)
 Universidade do Minho, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2019/11/18 - 2019/11/18 Participation in the course entitled as "DAY OF THE MICROBIOLOGY LABORATORY: Microbiology, Immunology and Oncobiology: Interdisciplinary approaches to control infectious diseases and cancer" DAY OF THE MICROBIOLOGY LABORATORY: Microbiology, Immunology and Oncobiology: Interdisciplinary approaches to control infectious diseases and cancer
Universidade do Porto Faculdade de Farmácia, Portugal
2018/10/25 - 2018/10/25 Attendance at the "IV Simpósio do Programa Doutoral em Biologia Molecular e Ambiental", aiming to provide an environment of scientific discussion between researchers, master and PhD students, who have here the opportunity to present their work.
Congresso
 IV Simpósio do Programa Doutoral em Biologia Molecular e Ambiental
Instituto de Ciência e Inovação para a Bio-Sustentabilidade da Universidade do Minho, Portugal
2018/06/08 - 2018/06/09 Attendance at the "XXI Jornadas de Biologia de Leveduras "Nicolau van Uden" aiming to disseminate and discuss results in the field of physiology, genetics and biotechnology of yeasts, in Portugal.
Congresso
 XXI Jornadas de Biologia de Leveduras “Nicolau van Uden
Universidade do Minho Escola de Ciências, Portugal
2017/04/10 - 2017/04/10 Participation in the workshop entitled "Host-Pathogen Interaction: Immune evasion of Candida albicans"
Oficina (workshop)
 X National Meeting of Student of Biochemistry (ENEBIOQ) - Science in Your Hands
Universidade do Minho Escola de Ciências, Portugal
2017/04/10 - 2017/04/10 Participation in the workshop entitled "Use of a fluorescent probe to study aggregation in micelles and Transfer of energy in membrane models to study the location of a drug"
Oficina (workshop)
 X National Meeting of Student of Biochemistry (ENEBIOQ) - Science in Your Hands
Universidade do Minho Escola de Ciências, Portugal
2017/04/07 - 2017/04/10 Attendance at the national meeting of students of Biochemistry at University of Minho, aiming to bring closer scientists from all over the country presenting the opportunity to discover a new scientific vision and knowledge.
Congresso
 X National Meeting of Student of Biochemistry (ENEBIOQ) - Science in Your Hands
Universidade do Minho Escola de Ciências, Portugal
2016/04/20 - 2016/04/20 Attendance at the "VIII Biochemistry day", organizaded by the Department of Chemistry and Nucleus of Chemistry Students of the Academic Association of the University of Aveiro (NEQ-AAUA)
Congresso
 VIII Biochemistry day
Universidade de Aveiro, Portugal
2016/03/09 - 2016/03/12 Attendance at the "VII Jornadas Nacionais de Ciências Biomédicas"
Congresso
 Jornadas Nacionais de Ciências Biomédicas
Universidade de Aveiro, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2021/02/04 - 2021/02/14 Attendance at the non-degree Continuing Training Unit: Biostatistics - linear and logistic regression Biostatistics - linear and logistic regression (Outros) Universidade do Porto Faculdade de Medicina, Portugal
2019/10/01 - 2019/12/15 Attendance at "26th edition of the introductory course in laboratory animal science" 26th edition of the introductory course in laboratory animal science (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016/07/11 - 2016/07/29 Observational internship of techniques used in animal cells to study the biochemical processes involved in the ageing process. Universidade de Aveiro Instituto de Biomedicina, Portugal