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Daniela Ribeiro presently is Associate Professor at Faculty of Agrarian Sciences and Environment, University of the Azores, and she recently joined the Institute for Research and Technology of Agronomy and Environment (IITAA) as integrated researcher. Daniela Ribeiro path in science started in 2007 as a volunteer student, during her MSc degree. In 2014 she concluded her Pharmaceutical Sciences PhD degree - Medicinal and Pharmaceutical Chemistry specialization, at FFUP. She has been actively disseminating the results and achievements of the scientific research she has been working on. She has published a total of 71 articles in international peer reviewed journals. She has also published book chapters, abstracts in indexed international and national journals, and participated in international and national conferences with oral communications and poster presentations. Three of these presentations won 1 best oral, 1 best poster and 1 travel awards. She has participated in several international and national research projects. She was the PI of 1 scientific research project at LAQV@REQUIMTE. She has a current h-index of 33, and a total of 12000+ citations (Scopus). She has also been supervising PhD students, Master degree students, and Undergraduated students (curricular units Project I and II of the MSc in Pharmaceutical Sciences of FFUP, First Degree in Biochemistry (ICBAS/FCUP), and international iternships). She is actively involved in the scientific community: Editorial Board for section 'Food Nutrition' - Foods, contribution as guest editor in special issues, collaboration with several scientific journals as reviewer (20+), participation in COST actions, and in the Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study. She also participates as responsible in the organization of Chemistry Olympics at University of the Azores.
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Identificação

Identificação pessoal

Nome completo
Daniela Sofia Almeida Ribeiro

Nomes de citação

  • Ribeiro, Daniela

Identificadores de autor

Ciência ID
F915-6D0F-B6EB
ORCID iD
0000-0001-9733-7934
Scopus Author Id
25626469800

Endereços de correio eletrónico

  • daniela.sa.ribeiro@uac.pt (Profissional)

Websites

Domínios de atuação

  • Ciências Exatas - Química

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2)
Formação
Grau Classificação
2016/06 - 2018/08
Concluído
 Carotenoid oxidation by reactive oxygen and nitrogen species: Chemical analysis and biological activity (Pós-doutoramento)
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
2016/03 - 2016/04
Concluído
 R&D Project - Applied Molecular Biosciences Unit (Pós-doutoramento)
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
2011 - 2014
Concluído
 Ciências Farmacêuticas (Doutoramento)
Especialização em Medicinal and Pharmaceutical Chemistry
Universidade do Porto Faculdade de Farmácia, Portugal
"Flavonoids with potential anti-inflammatory activity: in vitro structure/activity studies of their effects in proinflammatory signalling systems" (TESE/DISSERTAÇÃO)
 Approved with disctinction
2005 - 2010
Concluído
 Ciências Farmacêuticas (Mestrado integrado)
Universidade do Porto Faculdade de Farmácia, Portugal
 15
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2024 - Atual Investigador (Investigação) Universidade dos Açores Instituto de Investigação e Tecnologia da Agronomia e Meio Ambiente, Portugal
2021 - 2024 Investigador (Investigação) REQUIMTE LAQV Porto, Portugal
2018/10/08 - 2021/03/31 Investigador Contratado (Investigação) REQUIMTE LAQV Porto, Portugal
2015/01 - 2016/02 Investigador (Investigação) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2024/04 - Atual Professor Associado (Docente Universitário) Universidade dos Açores - Campus de Angra do Heroísmo, Portugal
2021/04/05 - 2024/03 Professor Auxiliar (Docente Universitário) Universidade dos Açores Departamento de Ciências Agrárias, Portugal
Universidade dos Açores Departamento de Ciências Agrárias, Portugal
2020/09 - 2021/02 Professor Auxiliar Convidado (Docente Universitário) Universidade do Porto Faculdade de Farmácia, Portugal

Outras Carreiras

Categoria Profissional
Instituição de acolhimento 		Empregador
2010/10 - 2011/02 Assistente (Técnico Superior de Saúde - Farmácia) Farmácia MAG, Portugal
Produções

Publicações

Artigo em conferência
  1. Vale, Abel; Lucas, Mariana; Ribeiro, Daniela; Fernandes, Eduarda. "Research into New Molecules with Anti-Inflammatory Activity". 2023.
    10.3390/ecb2023-14095
Artigo em revista
  1. Mensah, George A.; Fuster, Valentin; Murray, Christopher J.L.; Roth, Gregory A.; Abate, Yohannes Habtegiorgis; Abbasian, Mohammadreza; Abd-Allah, Foad; et al. "Global Burden of Cardiovascular Diseases and Risks, 1990-2022". Journal of the American College of Cardiology 82 25 (2023): 2350-2473. http://dx.doi.org/10.1016/j.jacc.2023.11.007.
    10.1016/j.jacc.2023.11.007
  2. Carina Proença; Marisa Freitas; Daniela Ribeiro; Ana T. Rufino; Eduarda Fernandes; José Miguel P. Ferreira de Oliveira. "The role of flavonoids in the regulation of epithelial-mesenchymal transition in cancer: A review on targeting signaling pathways and metastasis". Medicinal Research Reviews (2023): https://doi.org/10.1002/med.21966.
    10.1002/med.21966
  3. Wu, Dongze; Jin, Yingzhao; Xing, Yuhan; Abate, Melsew Dagne; Abbasian, Mohammadreza; Abbasi-Kangevari, Mohsen; Abbasi-Kangevari, Zeinab; et al. "Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019". eClinicalMedicine 64 (2023): 102193. http://dx.doi.org/10.1016/j.eclinm.2023.102193.
    10.1016/j.eclinm.2023.102193
  4. Steinmetz, Jaimie D; Culbreth, Garland T; Haile, Lydia M; Rafferty, Quinn; Lo, Justin; Fukutaki, Kai Glenn; Cruz, Jessica A; et al. "Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021". The Lancet Rheumatology 5 9 (2023): e508-e522. http://dx.doi.org/10.1016/s2665-9913(23)00163-7.
    10.1016/s2665-9913(23)00163-7
  5. Rufino, Ana T.; Freitas, Marisa; Proença, Carina; Ferreira de Oliveira, José M. P.; Fernandes, Eduarda; Ribeiro, Daniela. "Rheumatoid arthritis molecular targets and their importance to flavonoid-based therapy". Medicinal Research Reviews (2023): http://dx.doi.org/10.1002/med.21990.
    10.1002/med.21990
  6. Ong, Kanyin Liane; Stafford, Lauryn K; McLaughlin, Susan A; Boyko, Edward J; Vollset, Stein Emil; Smith, Amanda E; Dalton, Bronte E; et al. "Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021". The Lancet 402 10397 (2023): 203-234. http://dx.doi.org/10.1016/s0140-6736(23)01301-6.
    10.1016/s0140-6736(23)01301-6
  7. Pereira, Rui; Silva, Artur M.S.; Ribeiro, Daniela; Silva, Vera L.M.; Fernandes, Eduarda. "Bis-chalcones: A review of synthetic methodologies and anti-inflammatory effects". European Journal of Medicinal Chemistry 252 (2023): 115280. http://dx.doi.org/10.1016/j.ejmech.2023.115280.
    10.1016/j.ejmech.2023.115280
  8. Rufino, Ana Teresa; Lucas, Mariana; Silva, Artur M. S.; Ribeiro, Daniela; Fernandes, Eduarda. "2-Styrylchromones Prevent IL-1ß-Induced Pro-Inflammatory Activation of Fibroblast-like Synoviocytes while Increasing COX-2 Expression". Pharmaceutics 15 3 (2023): 780. http://dx.doi.org/10.3390/pharmaceutics15030780.
    10.3390/pharmaceutics15030780
  9. Freitas, Marisa; Proença, Carina; Ribeiro, Daniela; Quinaz-Garcia, Maria Beatriz; Araújo, Alberto N.; Fernandes, Eduarda. "Assessment of a-Amylase Activity in a Microanalysis System: Experimental Optimization and Evaluation of Type of Inhibition". Journal of Chemical Education 100 3 (2023): 1237-1245. http://dx.doi.org/10.1021/acs.jchemed.2c00392.
    10.1021/acs.jchemed.2c00392
  10. Burkart, Katrin; Causey, Kate; Cohen, Aaron J; Wozniak, Sarah S; Salvi, Devashri Digvijay; Abbafati, Cristiana; Adekanmbi, Victor; et al. "Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2·5 air pollution, 1990–2019: an analysis of data from the Global Burden of Disease Study 2019". The Lancet Planetary Health 6 7 (2022): e586-e600. http://dx.doi.org/10.1016/s2542-5196(22)00122-x.
    10.1016/s2542-5196(22)00122-x
  11. Sousa, Adelaide; Bradshaw, Tracey D.; Ribeiro, Daniela; Fernandes, Eduarda; Freitas, Marisa. "Pro-inflammatory effects of silver nanoparticles in the intestine". Archives of Toxicology 96 6 (2022): 1551-1571. http://dx.doi.org/10.1007/s00204-022-03270-w.
    10.1007/s00204-022-03270-w
  12. Tânia Laranjeira; Ana Costa; Catarina Faria-Silva; Daniela Ribeiro; José Miguel P. Ferreira de Oliveira; Sandra Simões; Andreia Ascenso. "Sustainable Valorization of Tomato By-Products to Obtain Bioactive Compounds: Their Potential in Inflammation and Cancer Management". Molecules 27 5 (2022): 1701-1701. https://doi.org/10.3390/molecules27051701.
    10.3390/molecules27051701
  13. Cousin, Ewerton; Duncan, Bruce B; Stein, Caroline; Ong, Kanyin Liane; Vos, Theo; Abbafati, Cristiana; Abbasi-Kangevari, Mohsen; et al. "Diabetes mortality and trends before 25 years of age: an analysis of the Global Burden of Disease Study 2019". The Lancet Diabetes & Endocrinology 10 3 (2022): 177-192. http://dx.doi.org/10.1016/s2213-8587(21)00349-1.
    10.1016/s2213-8587(21)00349-1
  14. Lucas, Mariana; Freitas, Marisa; Zanchetta, Marco; Silva, Artur M. S.; Fernandes, Eduarda; Ribeiro, Daniela. "2-Styrylchromones: Cytotoxicity and Modulation of Human Neutrophils’ Oxidative Burst". Pharmaceuticals 15 3 (2022): 288. http://dx.doi.org/10.3390/ph15030288.
    Publicado • 10.3390/ph15030288
  15. Martins, Thaise; Silva, Vera L.M.; Silva, Artur M.S.; Lima, José L.F.C.; Fernandes, Eduarda; Ribeiro, Daniela. "Chalcones as Scavengers of HOCl and Inhibitors of Oxidative Burst: Structure-Activity Relationship Studies". Medicinal Chemistry 18 1 (2022): 88-96. http://dx.doi.org/10.2174/1573406417666201230093207.
    10.2174/1573406417666201230093207
  16. Lucas, Mariana; Freitas, Marisa; Silva, Artur M. S.; Fernandes, Eduarda; Ribeiro, Daniela. "Styrylchromones: Biological Activities and Structure-Activity Relationship". Oxidative Medicine and Cellular Longevity 2021 (2021): 1-47. http://dx.doi.org/10.1155/2021/2804521.
    10.1155/2021/2804521
  17. Kinyoki, Damaris; Osgood-Zimmerman, Aaron E.; Bhattacharjee, Natalia V.; Schaeffer, Lauren E.; Lazzar-Atwood, Alice; Lu, Dan; Ewald, Samuel B.; et al. "Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018". Nature Medicine 27 10 (2021): 1761-1782. http://dx.doi.org/10.1038/s41591-021-01498-0.
    10.1038/s41591-021-01498-0
  18. Rocha, Sónia; Lucas, Mariana; Ribeiro, Daniela; Corvo, M. Luísa; Fernandes, Eduarda; Freitas, Marisa. "Nano-based drug delivery systems used as vehicles to enhance polyphenols therapeutic effect for diabetes mellitus treatment". Pharmacological Research 169 (2021): 105604. http://dx.doi.org/10.1016/j.phrs.2021.105604.
    Publicado • 10.1016/j.phrs.2021.105604
  19. Lucas, Mariana; Freitas, Marisa; Xavier, Jadriane A.; Moura, Fabiana A.; Goulart, Marília O. F.; Ribeiro, Daniela; Fernandes, Eduarda. "The scavenging effect of curcumin, piperine and their combination against physiological relevant reactive pro-oxidant species using in vitro non-cellular and cellular models". Chemical Papers (2021): http://dx.doi.org/10.1007/s11696-021-01710-y.
    10.1007/s11696-021-01710-y
  20. Carina Proença; Daniela Ribeiro; Marisa Freitas; Félix Carvalho; Eduarda Fernandes. "A comprehensive review on the antidiabetic activity of flavonoids targeting PTP1B and DPP-4: a structure-activity relationship analysis". Critical Reviews in Food Science and Nutrition (2021): 1-57. https://doi.org/10.1080/10408398.2021.1872483.
    10.1080/10408398.2021.1872483
  21. Carina Proença; Daniela Ribeiro; Marisa Freitas; Eduarda Fernandes. "Flavonoids as potential agents in the management of type 2 diabetes through the modulation of a-amylase and a-glucosidase activity: a review". Critical Reviews in Food Science and Nutrition (2021): https://doi.org/10.1080/10408398.2020.1862755.
    10.1080/10408398.2020.1862755
  22. Paulson, K.R.; Kamath, A.M.; Alam, T.; Bienhoff, K.; Abady, G.G.; Abbas, J.; Abbasi-Kangevari, M.; et al. "Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019". The Lancet 398 10303 (2021): 870-905. http://www.scopus.com/inward/record.url?eid=2-s2.0-85114514329&partnerID=MN8TOARS.
    10.1016/S0140-6736(21)01207-1
  23. Murray, Christopher J L; Aravkin, Aleksandr Y; Zheng, Peng; Abbafati, Cristiana; Abbas, Kaja M; Abbasi-Kangevari, Mohsen; Abd-Allah, Foad; et al. "Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 396 10258 (2020): 1223-1249. http://dx.doi.org/10.1016/s0140-6736(20)30752-2.
    10.1016/s0140-6736(20)30752-2
  24. Vos, Theo; Lim, Stephen S; Abbafati, Cristiana; Abbas, Kaja M; Abbasi, Mohammad; Abbasifard, Mitra; Abbasi-Kangevari, Mohsen; et al. "Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 396 10258 (2020): 1204-1222. http://dx.doi.org/10.1016/s0140-6736(20)30925-9.
    10.1016/s0140-6736(20)30925-9
  25. Ribeiro, Daniela; Sousa, Adelaide; Nicola, Pedro; Ferreira de Oliveira, José Miguel P.; Rufino, Ana T.; Silva, Marta; Freitas, Marisa; Carvalho, Félix; Fernandes, Eduarda. "ß-Carotene and its physiological metabolites: Effects on oxidative status regulation and genotoxicity in in vitro models". Food and Chemical Toxicology 141 (2020): 111392. http://dx.doi.org/10.1016/j.fct.2020.111392.
    10.1016/j.fct.2020.111392
  26. Proença, Carina; Oliveira, Ana; Freitas, Marisa; Ribeiro, Daniela; Sousa, Joana L. C.; Ramos, Maria J.; Silva, Artur M. S.; Fernandes, Pedro A.; Fernandes, Eduarda. "Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase". Journal of Natural Products 83 5 (2020): 1541-1552. http://dx.doi.org/10.1021/acs.jnatprod.0c00014.
    10.1021/acs.jnatprod.0c00014
  27. Freitas, Marisa; Lucas, Mariana; Sousa, Adelaide; Soares, Tânia; Ribeiro, Daniela; Carvalho, Félix; Fernandes, Eduarda. "Small-size silver nanoparticles stimulate neutrophil oxidative burst through an increase of intracellular calcium levels". World Academy of Sciences Journal 2 5 (2020): 1-8. http://dx.doi.org/10.3892/wasj.2020.46.
    Acesso aberto • Publicado • 10.3892/wasj.2020.46
  28. Adelaide Sousa; Daniela Ribeiro; Eduarda Fernandes; Marisa Freitas. "The effect of chalcones on the main sources of reactive species production: possible therapeutic implications in diabetes mellitus". Current Medicinal Chemistry (2020): https://doi.org/10.2174/0929867327666200525010007.
    No prelo • 10.2174/0929867327666200525010007
  29. Sousa, A.; Lucas, M.; Ribeiro, D.; Correia, C.M.; Silva, V.L.M.; Silva, A.M.S.; Fernandes, E.; Freitas, M.. "Chalcones as Modulators of Neutrophil Oxidative Burst under Physiological and High Glucose Conditions". Journal of Natural Products 83 10 (2020): 3131-3140. http://www.scopus.com/inward/record.url?eid=2-s2.0-85094220486&partnerID=MN8TOARS.
    10.1021/acs.jnatprod.0c00728
  30. Proença C; Freitas M; Ribeiro D; Tomé SM; Oliveira EFT; Viegas MF; Araújo AN; et al. "Evaluation of a flavonoids library for inhibition of pancreatic a-amylase towards a structure-activity relationship.". Journal of enzyme inhibition and medicinal chemistry (2019): http://europepmc.org/abstract/med/30724629.
    10.1080/14756366.2018.1558221
  31. Ribeiro, Daniela; Poença, Carina; Varela, Carla; Janela, João; Tavares da Silva, Elisiário J.; Fernandes, Eduarda; Roleira, Fernanda M.F.. "New phenolic cinnamic acid derivatives as selective COX-2 inhibitors. Design, synthesis, biological activity and structure-activity relationships". Bioorganic Chemistry 91 (2019): 103179. http://dx.doi.org/10.1016/j.bioorg.2019.103179.
    Publicado • 10.1016/j.bioorg.2019.103179
  32. Casas, María P.; Conde, Enma; Ribeiro, Daniela; Fernandes, Eduarda; Domínguez, Herminia; Torres, M. D.. "Bioactive properties of Acacia dealbata flowers extracts". Waste and Biomass Valorization (2019): 1-9. http://dx.doi.org/10.1007/s12649-019-00639-4.
    Publicado • 10.1007/s12649-019-00639-4
  33. Soares, Tânia; Rodrigues, Daniela; Sarraguça, Mafalda; Rocha, Sílvia; Lima, José L. F. C.; Ribeiro, Daniela; Fernandes, Eduarda; Freitas, Marisa. "Optimization of Experimental Settings for the Assessment of Reactive Oxygen Species Production by Human Blood". Oxidative Medicine and Cellular Longevity 2019 (2019): 1-11. http://dx.doi.org/10.1155/2019/7198484.
    Acesso aberto • Publicado • 10.1155/2019/7198484
  34. Proença, Carina; Freitas, Marisa; Ribeiro, Daniela; Tomé, Sara M.; Araújo, Alberto N.; Silva, Artur M. S.; Fernandes, Pedro A.; Fernandes, Eduarda. "The dipeptidyl peptidase-4 inhibitory effect of flavonoids is hindered in protein rich environments". Food & Function (2019): http://dx.doi.org/10.1039/c9fo00722a.
    No prelo • 10.1039/c9fo00722a
  35. Rocha, Sónia; Sousa, Adelaide; Ribeiro, Daniela; Correia, Catarina M.; Silva, Vera L. M.; Santos, Clementina M. M.; Silva, Artur M. S.; et al. "A study towards drug discovery for the management of type 2 diabetes mellitus through inhibition of the carbohydrate-hydrolyzing enzymes a-amylase and a-glucosidase by chalcone derivatives". Food & Function (2019): http://dx.doi.org/10.1039/c9fo01298b.
    No prelo • 10.1039/c9fo01298b
  36. Fitzmauric, C.; Fitzmaurice, C.; Abate, D.; Abbasi, N.; Abbastabar, H.; Abd-Allah, F.; Abdel-Rahman, O.; et al. "Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived with Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study". JAMA Oncology (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85072768207&partnerID=MN8TOARS.
    10.1001/jamaoncol.2019.2996
  37. Rocha, S.; Sousa, A.; Ribeiro, D.; Correia, C.M.; Silva, V.L.M.; Santos, C.M.M.; Silva, A.M.S.; et al. "Correction: A study towards drug discovery for the management of type 2 diabetes: Mellitus through inhibition of the carbohydrate-hydrolyzing enzymes a-amylase and a-glucosidase by chalcone derivatives (Food and Function (2019) DOI: 10.1039/c9fo01298b)". Food and Function 10 9 (2019): 6203-6203. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072358354&partnerID=MN8TOARS.
    10.1039/c9fo90045d
  38. Ribeiro D (corresponding author); Freitas M; Rocha S; Lima JLFC; Carvalho F; Fernandes E (corresponding author). "Calcium Pathways in Human Neutrophils-The Extended Effects of Thapsigargin and ML-9.". Cells (2018): http://europepmc.org/abstract/med/30423935.
    10.3390/cells7110204
  39. Rocha S; Ribeiro D; Fernandes E; Freitas M. "Systematic review on anti-diabetic properties of chalcones.". Current medicinal chemistry (2018): http://europepmc.org/abstract/med/30277140.
    10.2174/0929867325666181001112226
  40. Ribeiro, D. (corresponding author); Freitas, M.; Silva, A.M.S.; Carvalho, F.; Fernandes, E. (corresponding author). "Antioxidant and pro-oxidant activities of carotenoids and their oxidation products". Food and Chemical Toxicology 120 (2018): 681-699. http://www.scopus.com/inward/record.url?eid=2-s2.0-85051378743&partnerID=MN8TOARS.
    10.1016/j.fct.2018.07.060
  41. Ribeiro, D. (corresponding author); Proença, C.; Rocha, S.; Lima, J.L.F.C.; Carvalho, F.; Fernandes, E.; Freitas, M.. "Immunomodulatory effects of flavonoids in the prophylaxis and treatment of inflammatory bowel diseases: A comprehensive review". Current Medicinal Chemistry 25 28 (2018): 3374-3412. http://www.scopus.com/inward/record.url?eid=2-s2.0-85046370873&partnerID=MN8TOARS.
    10.2174/0929867325666180214121734
  42. Proença, C.; Freitas, M.; Ribeiro, D.; Sousa, J.L.C.; Carvalho, F.; Silva, A.M.S.; Fernandes, P.A.; Fernandes, E.. "Inhibition of protein tyrosine phosphatase 1B by flavonoids: A structure - activity relationship study". Food and Chemical Toxicology 111 (2018): 474-481. http://www.scopus.com/inward/record.url?eid=2-s2.0-85037682773&partnerID=MN8TOARS.
    10.1016/j.fct.2017.11.039
  43. Boeing, J.S.; Ribeiro, D.; Chisté, R.C.; Visentainer, J.V.; Costa, V.M.; Freitas, M.; Fernandes, E.. "Chemical characterization and protective effect of the Bactris setosa Mart. fruit against oxidative/nitrosative stress". Food Chemistry 220 (2017): 427-437. http://www.scopus.com/inward/record.url?eid=2-s2.0-84991478616&partnerID=MN8TOARS.
    10.1016/j.foodchem.2016.09.188
  44. Proença, C.; Freitas, M.; Ribeiro, D.; Oliveira, E.F.T.; Sousa, J.L.C.; Tomé, S.M.; Ramos, M.J.; et al. "a-Glucosidase inhibition by flavonoids: an in vitro and in silico structure–activity relationship study". Journal of Enzyme Inhibition and Medicinal Chemistry 32 1 (2017): 1216-1228. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029757909&partnerID=MN8TOARS.
    10.1080/14756366.2017.1368503
  45. Santos, C.M.M.; Ribeiro, D.; Silva, A.M.S.; Fernandes, E.. "2,3-Diarylxanthones as potential inhibitors of arachidonic acid metabolic pathways". Inflammation 40 3 (2017): 956-964. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021641003&partnerID=MN8TOARS.
    10.1007/s10753-017-0540-6
  46. Proença, C.; Ribeiro, D.; Soares, T.; Tomé, S.M.; Silva, A.M.S.; Lima, J.L.F.C.; Fernandes, E.; Freitas, M.. "Chlorinated Flavonoids Modulate the Inflammatory Process in Human Blood". Inflammation (2017): 1-11. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017415236&partnerID=MN8TOARS.
    10.1007/s10753-017-0559-8
  47. Flórez, N.; González-Muñoz, M.J.; Ribeiro, D.; Fernandes, E.; Domínguez, H.; Freitas, M.. "Algae polysaccharides' chemical characterization and their role in the inflammatory process". Current Medicinal Chemistry 24 2 (2017): 149-175. http://www.scopus.com/inward/record.url?eid=2-s2.0-85012034485&partnerID=MN8TOARS.
    10.2174/092986732366616102
  48. Kupski, L.; Freitas, M.; Ribeiro, D.; Furlong, E.B.; Fernandes, E.. "Ochratoxin A activates neutrophils and kills these cells through necrosis, an effect eliminated through its conversion into ochratoxin a". Toxicology 368-369 (2016): 91-102. http://www.scopus.com/inward/record.url?eid=2-s2.0-84987862424&partnerID=MN8TOARS.
    10.1016/j.tox.2016.09.001
  49. Soares, T.; Ribeiro, D.; Proença, C.; Chisté, R.C.; Fernandes, E.; Freitas, M.. "Size-dependent cytotoxicity of silver nanoparticles in human neutrophils assessed by multiple analytical approaches". Life Sciences 145 (2016): 247-254. http://www.scopus.com/inward/record.url?eid=2-s2.0-84953293078&partnerID=MN8TOARS.
    10.1016/j.lfs.2015.12.046
  50. Chisté, R.C.; Ribeiro, D.; Freitas, M.; Leite, A.; Moniz, T.; Rangel, M.; Fernandes, E.. "Uncovering novel 3-hydroxy-4-pyridinone metal ion complexes with potential anti-inflammatory properties". Journal of Inorganic Biochemistry 155 (2016): 9-16. http://www.scopus.com/inward/record.url?eid=2-s2.0-84947708390&partnerID=MN8TOARS.
    10.1016/j.jinorgbio.2015.11.009
  51. Barizão, T.O.; Visentainer, J.V.; de Cinque Almeida, V.; Ribeiro, D.; Chisté, R.C.; Fernandes, E.. "Citharexylum solanaceum fruit extracts: Profiles of phenolic compounds and carotenoids and their relation with ROS and RNS scavenging capacities". Food Research International 86 (2016): 24-33. http://www.scopus.com/inward/record.url?eid=2-s2.0-84969785392&partnerID=MN8TOARS.
    10.1016/j.foodres.2016.05.007
  52. Casas, M.P.; Rodríguez-Hermida, V.; Pérez-Larrán, P.; Conde, E.; Liveri, M.T.; Ribeiro, D.; Fernandes, E.; Domínguez, H.. "In vitro bioactive properties of phlorotannins recovered from hydrothermal treatment of Sargassum muticum". Separation and Purification Technology 167 (2016): 117-126. http://www.scopus.com/inward/record.url?eid=2-s2.0-84967102605&partnerID=MN8TOARS.
    10.1016/j.seppur.2016.05.003
  53. Proença, C.; Albuquerque, H.M.T.; Ribeiro, D.; Freitas, M.; Santos, C.M.M.; Silva, A.M.S.; Fernandes, E.. "Novel chromone and xanthone derivatives: Synthesis and ROS/RNS scavenging activities". European Journal of Medicinal Chemistry 115 (2016): 381-392. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961962762&partnerID=MN8TOARS.
    10.1016/j.ejmech.2016.03.043
  54. Gomes, A.; Capela, J.P.; Ribeiro, D.; Freitas, M.; Silva, A.M.S.; Pinto, D.C.G.A.; Santos, C.M.M.; et al. "Inhibition of NF-kB Activation and Cytokines Production in THP-1 Monocytes by 2-Styrylchromones". Medicinal Chemistry 11 6 (2015): 560-566. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938564231&partnerID=MN8TOARS.
  55. Carvalho, L.C.R.; Ribeiro, D.; Seixas, R.S.G.R.; Silva, A.M.S.; Nave, M.; Martins, A.C.; Erhardt, S.; et al. "Synthesis and evaluation of new benzimidazole-based COX inhibitors: A naproxen-like interaction detected by STD-NMR". RSC Advances 5 61 (2015): 49098-49109. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930960596&partnerID=MN8TOARS.
    10.1039/c5ra04984a
  56. Ribeiro, D.; Freitas, M.; Lima, J.L.F.C.; Fernandes, E.. "Proinflammatory Pathways: The Modulation by Flavonoids". Medicinal Research Reviews 35 5 (2015): 877-936. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938743566&partnerID=MN8TOARS.
    10.1002/med.21347
  57. Ribeiro, A.B.; Berto, A.; Ribeiro, D.; Freitas, M.; Chisté, R.C.; Visentainer, J.V.; Fernandes, E.. "Stem bark and flower extracts of Vismia cauliflora are highly effective antioxidants to human blood cells by preventing oxidative burst in neutrophils and oxidative damage in erythrocytes". Pharmaceutical Biology 53 11 (2015): 1691-1698. http://www.scopus.com/inward/record.url?eid=2-s2.0-84945977356&partnerID=MN8TOARS.
    10.3109/13880209.2014.1001407
  58. Ribeiro, D.; Freitas, M.; Tomé, S.M.; Silva, A.M.S.; Laufer, S.; Lima, J.L.F.C.; Fernandes, E.. "Flavonoids Inhibit COX-1 and COX-2 Enzymes and Cytokine/Chemokine Production in Human Whole Blood". Inflammation 38 2 (2015): 858-870. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939895701&partnerID=MN8TOARS.
    10.1007/s10753-014-9995-x
  59. Pistón, M.; Machado, I.; Branco, C.S.; Cesio, V.; Heinzen, H.; Ribeiro, D.; Fernandes, E.; Chisté, R.C.; Freitas, M.. "Infusion, decoction and hydroalcoholic extracts of leaves from artichoke (Cynara cardunculus L. subsp. cardunculus) are effective scavengers of physiologically relevant ROS and RNS". Food Research International 64 (2014): 150-156. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903472873&partnerID=MN8TOARS.
    10.1016/j.foodres.2014.05.078
  60. Freitas, M.; Ribeiro, D.; Tomé, S.M.; Silva, A.M.S.; Fernandes, E.. "Synthesis of chlorinated flavonoids with anti-inflammatory and pro-apoptotic activities in human neutrophils". European Journal of Medicinal Chemistry 86 (2014): 153-164. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906518198&partnerID=MN8TOARS.
    10.1016/j.ejmech.2014.08.035
  61. Ribeiro, D.; Freitas, M.; Tomé, S.M.; Silva, A.M.S.; Porto, G.; Cabrita, E.J.; Marques, M.M.B.; Fernandes, E.. "Inhibition of LOX by flavonoids: A structure-activity relationship study". European Journal of Medicinal Chemistry 72 (2014): 137-145. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890960018&partnerID=MN8TOARS.
    10.1016/j.ejmech.2013.11.030
  62. Freitas, M.; Costa, V.M.; Ribeiro, D.; Couto, D.; Porto, G.; Carvalho, F.; Fernandes, E.. "Acetaminophen prevents oxidative burst and delays apoptosis in human neutrophils". Toxicology Letters 219 2 (2013): 170-177. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876313471&partnerID=MN8TOARS.
    10.1016/j.toxlet.2013.03.007
  63. González, N.; Ribeiro, D.; Fernandes, E.; Nogueira, D.R.; Conde, E.; Moure, A.; Vinardell, M.P.; Mitjans, M.; Domínguez, H.. "Potential use of Cytisus scoparius extracts in topical applications for skin protection against oxidative damage". Journal of Photochemistry and Photobiology B: Biology 125 (2013): 83-89. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885026380&partnerID=MN8TOARS.
    10.1016/j.jphotobiol.2013.05.003
  64. Ribeiro, D.; Freitas, M.; Tomé, S.M.; Silva, A.M.S.; Porto, G.; Fernandes, E.. "Modulation of human neutrophils' oxidative burst by flavonoids". European Journal of Medicinal Chemistry 67 (2013): 280-292. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882515383&partnerID=MN8TOARS.
    10.1016/j.ejmech.2013.06.019
  65. Estevão, M.S.; Carvalho, L.C.; Ribeiro, D.; Couto, D.; Freitas, M.; Gomes, A.; Ferreira, L.M.; Fernandes, E.; Marques, M.M.B.. "Antioxidant activity of unexplored indole derivatives: Synthesis and screening". European Journal of Medicinal Chemistry 45 11 (2010): 4869-4878. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957850268&partnerID=MN8TOARS.
    10.1016/j.ejmech.2010.07.059
  66. Santos, C.M.M.; Freitas, M.; Ribeiro, D.; Gomes, A.; Silva, A.M.S.; Cavaleiro, J.A.S.; Fernandes, E.. "2,3-Diarylxanthones as strong scavengers of reactive oxygen and nitrogen species: A structure-activity relationship study". Bioorganic and Medicinal Chemistry 18 18 (2010): 6776-6784. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956342859&partnerID=MN8TOARS.
    10.1016/j.bmc.2010.07.044
  67. Couto, D.; Ribeiro, D.; Freitas, M.; Gomes, A.; Lima, J.L.F.C.; Fernandes, E.. "Scavenging of reactive oxygen and nitrogen species by the prodrug sulfasalazine and its metabolites 5-aminosalicylic acid and sulfapyridine". Redox Report 15 6 (2010): 259-267. http://www.scopus.com/inward/record.url?eid=2-s2.0-78651112199&partnerID=MN8TOARS.
    10.1179/135100010X12826446921707
  68. Gomes, A.; Neuwirth, O.; Freitas, M.; Couto, D.; Ribeiro, D.; Figueiredo, A.G.P.R.; Silva, A.M.S.; et al. "Synthesis and antioxidant properties of new chromone derivatives". Bioorganic and Medicinal Chemistry 17 20 (2009): 7218-7226. http://www.scopus.com/inward/record.url?eid=2-s2.0-71749101847&partnerID=MN8TOARS.
    10.1016/j.bmc.2009.08.056
Capítulo de livro
  1. Lucas, Mariana; Freitas, Marisa; Carvalho, Félix; Fernandes, Eduarda; Ribeiro, Daniela. "Antioxidant and Pro-oxidant Activities of Carotenoids". In Reference Series in Phytochemistry, 1-27. Springer International Publishing, 2022.
    Publicado • 10.1007/978-3-030-45299-5_4-1
  2. Adelaide Sousa; Ribeiro, Daniela; Eduarda Fernandes; Freitas, Marisa. "Silver nanoparticles: an approach to their synthesis, characterization and biological activities". In Advances in Nanotechnology, editado por Zacharie Bartul; Jérôme Trenor. Estados Unidos: Nova Science Publishers, 2022.
    Publicado
  3. Rahaman, Syed Nasar; Sivaprakasam, Prathiba; Pandurangan, Ashok Kumar; Anandasadagopan, Suresh Kumar. "Insights on the potential preventive and healing effects of flavonoids in inflammatory bowel disease". In Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer, 38-66. Estados Unidos: IGI Global, 2021.
    Publicado • 10.4018/978-1-7998-3580-6.ch004
  4. Rahaman, Syed Nasar; Sivaprakasam, Prathiba; Pandurangan, Ashok Kumar; Anandasadagopan, Suresh Kumar. "Inflammatory pathways and in vivo studies of inflammatory bowel disease". In Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer, 1-23. Estados Unidos: IGI Global, 2021.
    Publicado
  5. Ribeiro, Daniela; Fernandes, Eduarda; Freitas, Marisa. "Flavonoids as Modulators of Neutrophils' Oxidative Burst: Structure-Activity Relationship". In Polyphenols: Mechanisms of Action in Human Health and Disease, editado por Ronald Ross Watson; Victor R. Preedy, 261-276. Elsevier, 2018.
    Publicado
  6. Freitas, Marisa; Ribeiro, Daniela; Silva, Paula; Lima, Jose L.F.C.; Carvalho, Félix; Fernandes, Eduarda. "Proinflammatory and toxic effects of silver nanoparticles". In Nanoparticles in Life Sciences and Biomedicine, editado por Ana Rute Neves; Salette Reis, 505-529. Pan Stanford Publishing Pte. Ltd., 2018.
    Publicado
Poster em conferência
  1. Rui Pereira; Ribeiro, Daniela; Vera Silva; Eduarda Fernandes. "Synthesis and evaluation of novel polyhydroxylated bis-chalcones as potential COX-2 selective inhibitors". Trabalho apresentado em 58th International Conference on Medicinal Chemistry, 2024.
  2. Lucas, Mariana; Ribeiro, Daniela; Artur M. S. Silva; Eduarda Fernandes. "Exploring 2-styrylchromones as potential modulators of COX-2 activity and expression". Trabalho apresentado em XXVII Encontro Luso-Galego de Química, 2023.
  3. a. "Bis-chalcones: A new scaffold for novel and potent inhibitors of cyclooxygenase 2". Trabalho apresentado em XXVII Encontro Luso-Galego de Química, 2023.
  4. Rui Pereira; Silva, Vera L. M.; Artur M. S. Silva; Ribeiro, Daniela; Eduarda Fernandes. "Flash communication - Synthesis of novel polyhydroxylated bis-chalcones and their cyclodehydrogenation into bis-flavones". Trabalho apresentado em XXVIII Encontro Nacional da SPQ, 2023.
  5. Lucas, Mariana; Freitas, Marisa; Ribeiro, Daniela; Artur M. S. Silva; Eduarda Fernandes. "Exploring the potential of 2-styrylchromones as COX-2 inhibitors". Trabalho apresentado em 6th Symposium on Medicinal Chemistry of University of Minho, 2023.
  6. Abel Vale; Lucas, Mariana; Ribeiro, Daniela; Fernandes, Eduarda. "Research into new molecules with anti-inflammatory activity". Trabalho apresentado em 2nd International Electronic Conference on Biomedicines (ECB 2023), 2023.
  7. Rufino, Ana; Lucas, Mariana; Artur M. S. Silva; Eduarda Fernandes; Ribeiro, Daniela. Autor correspondente: Rufino, Ana. "2-Styrylchromones inhibit IL-1ß-induced inflammatory mediators’ production in human fibroblast-like synoviocytes". Trabalho apresentado em 8th International Electronic Conference on Medicinal Chemistry, 2022.
  8. Rui Pereira; Silva, Vera L. M.; Artur M. S. Silva; Ribeiro, Daniela; Eduarda Fernandes. "Synthesis and chemical reactivity of novel polyhydroxylated bis-chalcones". Trabalho apresentado em 8th International Electronic Conference on Medicinal Chemistry, 2022.
  9. Lucas, Mariana; Freitas, Marisa; Artur M. S. Silva; Eduarda Fernandes; Ribeiro, Daniela. "2-Styrylchromones modulate prostaglandins production through the inhibition of COX-2". Trabalho apresentado em 8th International Electronic Conference on Medicinal Chemistry, 2022.
  10. Mariana Lucas; Ribeiro, Daniela; Dania Shriki; Janela, João; Carla Varela; Elisiário J. Tavares da Silva; Eduarda Fernandes; Fernanda M. F. Roleira. "Ligand-base design, synthesis and structure-activity relationships of new phenolic cinnamic acid amides as selective cox-2 inhibitors". Trabalho apresentado em The XXVll EFMC International Symposium on Medicinal Chemistry, 2022.
  11. Mariana Lucas; Freitas, Marisa; Zanchetta, Marco; Silva, Vera L. M.; Artur M. S. Silva; Eduarda Fernandes; Ribeiro, Daniela. "Cytotoxicity and anti-inflammatory potential of 2-styrylchromones". Trabalho apresentado em ICT 2022 - The XVIth International Congress of Toxicology, 2022.
  12. Rocha, Sónia; Ribeiro, Daniela; Silva, Vera L. M.; Artur M. S. Silva; Corvo, M. Luísa; Eduarda Fernandes; Freitas, Marisa. "New insights on the inhibition of cyclooxygenases by 4-styrylpyrazoles: an enzymatic and cellular study". Trabalho apresentado em 4th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting, 2022.
  13. Mariana Lucas; Freitas, Marisa; Joana L.C. Sousa; Artur M. S. Silva; Eduarda Fernandes; Ribeiro, Daniela. "Evaluation of COX-2 inhibitory activity by hydroxylated and methoxylated 2-styrylchromones". Trabalho apresentado em 4th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting, 2022.
  14. Pereira, Rui; Silva, Vera L. M.; Artur M. S. Silva; Ribeiro, Daniela; Eduarda Fernandes. "Synthesis of new bis-chalcone scaffolds as potential inhibitors of cyclooxygenase 2". Trabalho apresentado em 4th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting, 2022.
  15. Kupski, Larine; Mendes, Gabriela Lemos; Ribeiro, Daniela; Freitas, Marisa; Fernandes, Eduarda; Badiale-Furlong, Eliana; Ribeiro, Anelise Christ. "OTA degradation by carboxypeptidase A: a study of mechanism and applicability". Trabalho apresentado em ILSI Europe Early Career Scientists Seminar on Food Contaminants: mycotoxins research and mitigation strategies in Europe and Latin America, 2021.
  16. Ricardo Monteiro; Lucas, Mariana; Marisa Freitas; Catarina M. Correia; Silva, Vera L. M.; Artur M. S. Silva; Eduarda Fernandes; Daniela Ribeiro. "Chalcones versus 2-styrylchromones: which are the best oxygen and nitrogen reactive species scavengers?". Trabalho apresentado em The 7th International Electronic Conference in Medicinal Chemistry, 2021.
  17. Lucas, Mariana; Marisa Freitas; Joana L.C. Sousa; Artur M. S. Silva; Eduarda Fernandes; Daniela Ribeiro. "The impact of B-ring substituents on the styrylchromones ability to modulate the levels of reactive prooxidant species". Trabalho apresentado em The 7th International Electronic Conference in Medicinal Chemistry, 2021.
  18. Adelaide Sousa; Rufino, Ana; Daniela Ribeiro; Eduarda Fernandes; Marisa Freitas. "Cytotoxic potential of silver nanoparticles to human neutrophils and monocytes". Trabalho apresentado em ‘Total-Nanosafe’ Hybrid Conference, 2021.
  19. Lucas, Mariana; Marisa Freitas; Artur M. S. Silva; Fernandes, Eduarda; Daniela Ribeiro. "The effects of methoxylated 2-styrylchromones on neutrophils’ viability and oxidative burst". Trabalho apresentado em 56th International Conference on Medicinal Chemistry 56èmes Rencontres Internationales de Chimie Thérapeutique, 2021.
  20. Moreira, Beatriz G.; Raquel Santos; Daniela Ribeiro; Fernandes, Eduarda; José M. P. Ferreira de Oliveira. "Avaliação de efeitos antiproliferativos e pró-oxidantes de flavonóides em modelos in vitro de osteossarcoma". Trabalho apresentado em Encontro Nacional de Estudantes de Bioquímica, 2021.
  21. Lucas, Mariana; Freitas, Marisa; Silva, Artur M. S.; Fernandes, Eduarda; Ribeiro, Daniela. "Modulation of human neutrophils oxidative burst by hydroxylated 2-styrylchromones: the relevance of the catechol group". Trabalho apresentado em 1st International Electronic Conference on Biomedicine, 2021.
  22. Moreira, Beatriz G.; Santos, Raquel A. M.; Ribeiro, Daniela; Fernandes, Eduarda; Ferreira de Oliveira, José Miguel P.. "Evaluation of cytotoxic effects of flavonoids in osteosarcoma cell lines based on cellular reductive metabolismo". Trabalho apresentado em Encontro de Investigação Jovem da Universidade do Porto (IJUP), 2021.
  23. Moreira, Beatriz G.; Santos, Raquel A. M.; Daniela Ribeiro; Fernandes, Eduarda; Ferreira de Oliveira, José Miguel P.. "Evaluation of cytotoxic effects of flavonoids in osteosarcoma cell lines based on cellular reductive metabolism". Trabalho apresentado em Encontro de Investigação Jovem da Universidade do Porto (IJUP), 2021.
  24. Ribeiro, Daniela. "In vitro protective effect of flavonoids against intestinal toxicity of silver nanoparticles". Trabalho apresentado em IberPhenol International Conference, 2020.
  25. Ribeiro, Daniela. "The potential of flavonoids as inhibitors of dipeptidyl peptidase-4 (DPP-4)". Trabalho apresentado em IberPhenol International Conference, 2020.
  26. Ribeiro, Daniela. "In vitro inhibitory activity of flavonoids against important targets related to type 2 diabetes mellitus". Trabalho apresentado em IberPhenol International Conference, 2020.
  27. Ribeiro, Daniela. "The protective effect of chalcones against human neutrophils’ oxidative burst and NETosis under hyperglycemic conditions". Trabalho apresentado em IberPhenol International Conference, 2020.
  28. Ribeiro, Daniela. "Antioxidant activity of curcumin and piperine extracts and respective combinations". Trabalho apresentado em IberPhenol International Conference, 2020.
  29. Ribeiro, Daniela. "Insight into the protein tyrosine phosphatase 1B (PTP1B) inhibitory activity of pyrazoles". Trabalho apresentado em 6th International Electronic Conference on Medicinal Chemistry, 2020.
  30. Lucas, Mariana; Freitas, Marisa; Silva, Artur; Fernandes, Eduarda; Ribeiro, Daniela. "Structure-related antioxidant and anti-inflammatory activities of flavonoids and 2-styrylchromones". Trabalho apresentado em 22nd International Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants - Paris Redox 2020, 2020.
  31. Freitas, Marisa; Sousa, Adelaide; Soares, Tânia; Ribeiro, Daniela; Carvalho, Félix; Fernandes, Eduarda. "The role of calcium in silver nanoparticles-induced human neutrophils' oxidative burst". Trabalho apresentado em SOT 59th Annual Meeting, 2020.
  32. Proença, Carina; Freitas, Marisa; Ribeiro, Daniela; Tomé, Sara M.; Silva, Artur M. S.; Fernandes, Pedro A.; Fernandes, Eduarda. "Flavonoids as modulators of key enzymes in the management of type 2 diabetes: a structure-activity relationship study". Trabalho apresentado em SOT 59th Annual Meeting, 2020.
  33. Marisa Freitas; Sónia Rocha; Carina Proença; Ribeiro, Daniela; Alberto N. Araújo; Artur M.S. Silva; Eduarda Fernandes. "Flavonoids versus chalcones: which are the most efficient inhibitors of key digestive enzymes in the management of diabetes mellitus?". Trabalho apresentado em 13th National Organic Chemistry Meeting - 6th National Medicinal Chemistry Meeting, 2020.
  34. Mariana Lucas; Ribeiro, Daniela; Marisa Freitas; Fabiana Moura; Jadriane Xavier; Marília Goulart; Eduarda Fernandes. "Evaluation of the antioxidant activity of curcumin and piperine extracts, and their combination, in in vitro cellular and noncellular systems". Trabalho apresentado em 13th National Organic Chemistry Meeting - 6th National Medicinal Chemistry Meeting, 2020.
  35. Carina Proença; Marisa Freitas; Ribeiro, Daniela; Sara M. Tomé; Artur M. S. Silva; Pedro A. Fernandes; Eduarda Fernandes. "The promising effect of flavonoids in type 2 diabetes therapy: inhibition of key enzymatic targets with a significant role in the development of hyperglycaemia". Trabalho apresentado em 13th National Organic Chemistry Meeting - 6th National Medicinal Chemistry Meeting, 2020.
  36. Ribeiro, Daniela; Carina Proença; Carla Varela; João Janela; Elisário J. Tavares da Silva; Roleira, Fernanda M.F.; Eduarda Fernandes. "Synthesis of new phenolic cinnamic acid derivatives and SAR evaluation of their COX-1 and COX-2 inhibitory effects in human blood". Trabalho apresentado em 13th National Organic Chemistry Meeting - 6th National Medicinal Chemistry Meeting, 2020.
  37. Ribeiro, Daniela; Carina Proença; Carla Varela; João Janela; Elisário J. Tavares da Silva; Eduarda Fernandes; Roleira, Fernanda M.F.. "New phenolic cinnamic acid derivatives as selective COX-2 inhibitors. Chemistry and structure-activity relationships". Trabalho apresentado em VIII EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry, 2019.
  38. Martins, Thaise (presenter); Sousa, Adelaide; Freitas, Marisa; Correia, Catarina; Silva, Vera; Silva, Artur; Lima, Jose L.F.C.; Fernandes, Eduarda; Ribeiro, Daniela. "Modulation of human neutrophils’ oxidative burst by 2’-hydroxychalcone derivative". Trabalho apresentado em FMC - ACSMEDI Medicinal Chemistry Frontiers, 2019.
  39. Sousa, Adelaide (presenter); Martins, Thaise; Correia, Catarina M.; Silva, Vera L.M.; Silva, Artur; Ribeiro, Daniela; Fernandes, Eduarda; Freitas, Marisa. "Impact of chalcones on reactive species production by human neutrophils in hyperglycaemia conditions". Trabalho apresentado em XX EuroFoodChem Congress, 2019.
  40. Proenca, Carina (presenter); Freitas, Marisa; Ribeiro, Daniela; Tomé, Sara; Araujo, Alberto; Silva, Artur; Fernandes, Pedro; Fernandes, Eduarda. "Dipeptidyl peptidase-4 inhibition by flavonoids is Hindered in protein rich environments". Trabalho apresentado em 11th Joint Meeting on Medicinal Chemistry 2019, 2019.
  41. Proenca, Carina; Freitas, Marisa (presenter); Ribeiro, Daniela; Tomé, Sara; Silva, Artur; Fernandes, Pedro; Fernandes, Eduarda. "Promising inhibitory activity of flavonoids against Important targets related with type 2 diabetes mellitus". Trabalho apresentado em 11th Joint Meeting on Medicinal Chemistry 2019, 2019.
  42. Ribeiro, Daniela (presenter); Proenca, Carina; varela, carla; janela, joão; Silva, Elisário; Fernandes, Eduarda; roleira, fernanda. "Synthesis and evaluation of new phenolic cinnamic acid derivatives as potential selective COX-2 inhibitors". Trabalho apresentado em 11th Joint Meeting on Medicinal Chemistry 2019, 2019.
  43. Fernandes, Eduarda; Rufino, Ana; Oliveira, Miguel; Ribeiro, Daniela; Sousa, Adelaide; Soares, Tânia; Gónzalez-Gómez, Manuel; et al. "Testing the effects of silver nanoparticles in in vitro models of intestinal toxicity and inflammation". Trabalho apresentado em 10th International Conference Biomaterials and Nanobiomaterials: Recent Advances Safety-Toxicology and Ecological Issues, 2019.
    10.13031/aim.20141912802
  44. Ribeiro, Daniela; Freitas, Marisa; Carvalho, Félix; Fernandes, Eduarda (presenter). "The extended effects of thapsigargin on human neutrophils’ calcium pathways". Trabalho apresentado em SOT 58th Annual Meeting and ToxExpo, 2019.
    10.1145/633292.633402
  45. Marta Silva (presenter); Félix Carvalho; Eduarda Fernandes; Ribeiro, Daniela. "Anti- versus pro-oxidant effects of the carotenoids ß-carotene, trans-ß-apo-8'-carotenal and ß-cryptoxanthin in a synaptosomal lipid peroxidation model". Trabalho apresentado em Encontro de Investigação Jovem da Universidade do Porto (IJUP) 2019, 2019.
  46. Proenca, Carina; Freitas, Marisa; Ribeiro, Daniela; Silva, A.M.S.; Fernandes, P.A.; Fernandes, Eduarda. "Development of in vitro and ex vivo methods for the evaluation of dipeptidyl peptidase-4 (DPP-4) activity". Trabalho apresentado em XXIV Encontro Luso-Galego de Química, 2018.
  47. Martins, Thaise (presenter); Ribeiro, Daniela; Lima, Jose L.F.C.; Fernandes, Eduarda. "Antioxidant activity of chalcones related to the scavenging of hypochlorous acid". Trabalho apresentado em XXIV Encontro Luso-Galego de Química, 2018.
  48. Proenca, Carina (presenter); Freitas, Marisa; Ribeiro, Daniela; Sousa, J.L.C.; Silva, A.M.S.; Fernandes, P.A.; Fernandes, Eduarda. "Inhibitory activity of flavonoids on digestive enzymes alpha-amylase and alpha-glucosidase". Trabalho apresentado em 10º Simpósio em Metabolismo, 2018.
  49. Martins, Thaise (presenter); Ribeiro, Daniela; Lima, Jose L.F.C.; Fernandes, Eduarda. "Scavenging of hypochlorous acid and modulation of neutrophil’s oxidative burst by methoxylated and hydroxylated chalcones". Trabalho apresentado em 10º Simpósio em Metabolismo, 2018.
  50. Nicola, Pedro (presenter); Freitas, Marisa; Rocha, Sónia; Carvalho, Félix; Fernandes, Eduarda; Ribeiro, Daniela. "Optimization of a synaptosomal model to study the effect of carotenoids in peroxynitrite - induced lipid peroxidation". Trabalho apresentado em YES (Young European Scientist) Meeting, 2018.
  51. Proenca, Carina (presenter); Freitas, Marisa; Ribeiro, Daniela; Silva, A.M.S.; Fernandes, P.A.; Fernandes, Eduarda. "The possible role of flavonoids in the management of type 2 diabetes mellitus: a structure-activity relationship on enzymes involved in hyperglycaemia". Trabalho apresentado em Italian-Spanish-Portuguese Joint Meeting in Medicinal Chemistry - MedChemSicily2018, 2018.
  52. Nicola, Pedro (presenter); Freitas, Marisa; Rocha, Sónia; Carvalho, Félix; Fernandes, Eduarda; Ribeiro, Daniela. "Synaptosomes as lipid models to study the inhibition of peroxynitrite - induced lipid peroxidation". Trabalho apresentado em Italian Spanish-Portuguese Joint Meeting in Medicinal Chemistry - MedChemSicily2018, 2018.
  53. Ribeiro, Daniela (presenter); Soares, Tânia; Rocha, Sónia; Sarraguça, Mafalda; Fernandes, Eduarda; Freitas, Marisa. "Optimization of experimental settings for the assessment of HOCl in human blood, using the fluorescent probe APF". Trabalho apresentado em 19th Biennial Meeting for the Society for Free Radical Research International (SFRRI), 2018.
  54. Sousa, Adelaide (presenter); Rocha, Sílvia; Freitas, Marisa; Ribeiro, Daniela; Fernandes, Eduarda. "Effect of ß-Carotene and its oxidation products in the oxidative burst of human neutrophils". Trabalho apresentado em XXIII Encontro Galego-Portugues de Química, 2017.
  55. Ribeiro, Daniela (presenter); Sousa, Adelaide; Rocha, Sílvia; Freitas, Marisa; Fernandes, Eduarda. "ß-Carotene and its biological oxidation products: are they good modulators of pro-oxidant reactive species in human blood and neutrophils assay systems?". Trabalho apresentado em Meeting of the International HNE-Club and the University of Graz - Reactive Oxygen Species and Lipid Peroxidation in Human Health and Disease, 2017.
  56. Proenca, Carina (presenter); Ribeiro, Daniela; Tomé, S.M.; Silva, A.M.S.; Freitas, Marisa; Fernandes, Eduarda. "Inhibition of alpha-glucosidase by chlorinated flavonoids". Trabalho apresentado em Encontro de Investigação Jovem da Universidade do Porto - 9ª Edição, 2017.
  57. Ribeiro, Daniela (presenter); Tomé, S.M.; Proenca, Carina; Silva, A.M.S.; Freitas, Marisa; Fernandes, Eduarda. "Flavonoids can mediate inflammation resolution through inhibition of human neutrophils’ oxidative burst and leukotriene B4 production". Trabalho apresentado em The Society For Leukocytes Biology’s 49th Annual Meeting and “Neutrophil 2016”, 2016.
  58. Proenca, Carina (presenter); Ribeiro, Daniela; Tomé, S.M.; Silva, A.M.S.; Fernandes, Eduarda; Freitas, Marisa. "Chlorinated flavonoids are effective modulators of hypochlorous acid production, both in isolated human neutrophils and whole blood". Trabalho apresentado em The Society For Leukocytes Biology’s 49th Annual Meeting and “Neutrophil 2016”, 2016.
  59. Freitas, Marisa (presenter); Proenca, Carina; Ribeiro, Daniela; Fernandes, Eduarda. "Assessing the production of reactive oxygen and nitrogen species by human neutrophils". Trabalho apresentado em The Society For Leukocytes Biology’s 49th Annual Meeting and “Neutrophil 2016”, 2016.
  60. Boeing, J.S. (presenter); Ribeiro, Daniela; Costa, V.M.; Visentainer, Jesuí Vergílio; Freitas, Marisa; Fernandes, Eduarda. "Bactris setosa, an underexploited brazilian fruit, shows protective effects against oxidative cellular damage". Trabalho apresentado em Sociedade Portuguesa de Química - Divisão de Química Alimentar, 2016.
  61. Chisté, Renan Campos (presenter); Ribeiro, Daniela; Freitas, Marisa; Leite, A.; Moniz, T.; Rangel, M.; Fernandes, Eduarda. "Metal ion complexes with 3-hydroxy-4-pyridinone ligands as inhibitors of neutrophils’ oxidative burst". Trabalho apresentado em Congresso de Química Orgânica e Química Terapêutica, 2015.
  62. Proenca, Carina (presenter); Freitas, Marisa; Ribeiro, Daniela; Sousa, J.L.C.; Silva, A.M.S.; Fernandes, Eduarda. "In vitro antioxidant activity of novel 3-hydroxy-2-stytrylchromones as compared to 3-hydroxyflavones". Trabalho apresentado em Congresso de Química Orgânica e Química Terapêutica, 2015.
  63. Silva, Paula (presenter); Ribeiro, Daniela; Proenca, Carina; Fernandes, Eduarda; Freitas, Marisa. "The effect of flavonoids in inflammatory pathways". Trabalho apresentado em 7th International Conference on Polyphenols and Health (ICPH), 2015.
  64. Ribeiro, Daniela (presenter); Kupski, Larine; Furlong, E. Badiale; Freitas, Marisa; Fernandes, Eduarda. "Pro-inflammatory and toxic effects of ochratoxin and ochratoxin a in human neutrophils". Trabalho apresentado em 51st Congress of the European Society of Toxicology (EUROTOX), 2015.
  65. Soares, Tânia (presenter); Ribeiro, Daniela; Fernandes, Eduarda; Freitas, Marisa. "Size-dependent cytotoxicity of silver nanoparticles in human neutrophils". Trabalho apresentado em 51st Congress of the European Society of Toxicology (EUROTOX), 2015.
  66. Ribeiro, Daniela (presenter); Freitas, Marisa; Fernandes, Eduarda. "Effect of flavonoids in the human neutrophils’ apoptotic pathways". Trabalho apresentado em 9th World Congress on Polyphenols Applications, 2015.
  67. Freitas, Marisa (presenter); Ribeiro, Daniela; Tomé, S.M.; Silva, A.M.S.; Fernandes, Eduarda. "Chlorinated flavonoids modulate the oxidative burst of inflammatory cells". Trabalho apresentado em 9th World Congress on Polyphenols Applications, 2015.
  68. Freitas, Marisa (presenter); Ribeiro, Daniela; Tomé, S.M.; Silva, A.M.S.; Fernandes, Eduarda. "Chlorinated flavonoids as potential modulators of apoptosis in human neutrophils". Trabalho apresentado em XX Encontro Luso-Galego de Química, 2014.
  69. Ribeiro, Daniela (presenter); Freitas, Marisa; Lima, Jose L.F.C.; Fernandes, Eduarda. "Flavonoids inhibit the production of cytokines/chemokines and induce apoptosis in human neutrophils". Trabalho apresentado em SFRR-Europe 2014 Meeting, 2014.
  70. Freitas, Marisa (presenter); Ribeiro, Daniela; Tomé, S.M.; Silva, A.M.S.; Fernandes, Eduarda. "Anti-inflammatory and pro-apoptotic activities of chlorinated flavonoids in human neutrophils". Trabalho apresentado em SFRR-Europe 2014 Meeting, 2014.
  71. Ribeiro, Alessandra Braga (presenter); Berto, Alessandra; Ribeiro, Daniela; Freitas, Marisa; Chisté, Renan Campos; Visentainer, Jesuí Vergílio; Fernandes, Eduarda. "Stem bark and flower extracts of Vismia cauliflora: modulation of oxidative burst in human neutrophils and inhibition of oxidative damage in human erythrocytes". Trabalho apresentado em SFRR-Europe 2014 Meeting, 2014.
  72. Freitas, Marisa (presenter); Costa, V.M.; Ribeiro, Daniela; Couto, Diana; Porto, G.; Carvalho, Félix; Fernandes, Eduarda. "Acetaminophen prevents oxidative burst and delays apoptosis in human neutrophils in vitro". Trabalho apresentado em 2nd International Conference on Ocupacional and Environmental Toxicology 2013, 2013.
  73. Ribeiro, Daniela (presenter); Freitas, Marisa; Tomé, S.M.; Silva, A.M.S.; Porto, G.; Fernandes, Eduarda. "A structure-activity relationship study of flavonoids as dual inhibitors of LOX and COX". Trabalho apresentado em SFRR - Europe 2013 Meeting, 2013.
  74. Ribeiro, Daniela (presenter); Freitas, Marisa; Tomé, S.M.; Silva, A.M.S.; Porto, G.; Fernandes, Eduarda. "Flavonoids and LOX – an interaction and inhibition study". Trabalho apresentado em XXIII Encontro Nacional da SPQ, 2013.
  75. Ribeiro, Daniela (presenter); Freitas, Marisa; Tomé, S.M.; Silva, A.M.S.; Porto, G.; Fernandes, Eduarda. "Flavonoids as modulators of human neutrophils’ oxidative burst". Trabalho apresentado em The 16th biennial meeting for the Society for Free Radical Research International (SFRRI), 2012.
  76. Conde, E. (presenter); Balboa, E. M.; Reinoso, B. D.; Ribeiro, Daniela; Freitas, Marisa; Fernandes, Eduarda; Moure, A.; Domínguez, H.; Parajó, J. C.. "Screening of anti-inflammatory potencial in natural extracts with high polyphenolic content". Trabalho apresentado em Jornada de investigación Biomédica, 2012.
  77. Ribeiro, Daniela (presenter); Freitas, Marisa; Tomé, S.M.; Silva, A.M.S.; Porto, G.; Fernandes, Eduarda. "Modulation of human neutrophils oxidative burst by flavonoids". Trabalho apresentado em Environmental Stressors in Biology and Medicine, 2011.
  78. Ribeiro, Daniela (presenter); Alves, Andreia; Fernandes, Eduarda. "Actividade antioxidante de derivados da 3-hidroxiflavona em sistemas in vitro". Trabalho apresentado em IV Congresso Ibero-americano de Ciências Farmacêuticas, 2011.
  79. Ribeiro, Daniela (presenter); Fernandes, Eduarda. "COX/LOX Dual Activity – A novel and rational approach towards inflammation". Trabalho apresentado em IJUP’11 4th meeting of young researchers of U. Porto, 2011.
  80. Santos, C.M.M. (presenter); Freitas, Marisa; Ribeiro, Daniela; Gomes, Ana; Silva, A.M.S.; Cavaleiro, J.A.S.; Fernandes, Eduarda. "NDPO2 as a selective generator of 1O2 used in the scavenging activity assay of 2, 3 – diarylxanthones". Trabalho apresentado em Segundo Simpósio Iberoamericano de Química Orgânica (SIBEAQO-II), 2010.
  81. Santos, C.M.M. (presenter); Freitas, Marisa; Ribeiro, Daniela; Gomes, Ana; Silva, A.M.S.; Cavaleiro, J.A.S.; Fernandes, Eduarda. "ROS and RNS scavenging activity by 2,3-diarylxanthones". Trabalho apresentado em International Symposium on the Patophysiology of reactive oxygen and nitrogen species, 2010.
  82. Ribeiro, Daniela (presenter); Couto, Diana; Alves, Andreia; Gomes, Ana; Freitas, Marisa; Fernandes, Eduarda; Lima, Jose L.F.C.. "Scavenging activities of sulfasalazine and its metabolites, sulfapyridine and 5-aminosalicylic acid, against reactive oxygen species". Trabalho apresentado em IJUP’10 3rd meeting of young researchers of U. Porto, 2010.
  83. Couto, Diana (presenter); Ribeiro, Daniela; Costa, Diana; Gomes, Ana; Freitas, Marisa; Fernandes, Eduarda. "Scavenging activities of sulfasalazine and its metabolites, sulfapyridine and 5-aminosalicylic acid, against reactive nitrogen species". Trabalho apresentado em IJUP’10 3rd meeting of young researchers of U. Porto, 2010.
  84. Reis, Rita (presenter); Ribeiro, Daniela; Gomes, Ana; Freitas, Marisa; Estevão, M.S.; Marques, M.M.B.; Lima, José Luís Costa; Fernandes, Eduarda. "Inhibition of cyclooxygenases by new indole derivatives". Trabalho apresentado em IJUP’10 3rd meeting of young researchers of U. Porto, 2010.
  85. Lima, Jose L.F.C. (presenter); Gomes, Ana; Neuwirth, O.; Freitas, Marisa; Couto, Diana; Ribeiro, Daniela; Figureiredo, A.G.P.R.; et al. "Utilização da di-hidrorodamina 123 para a detecção de espécies reactivas de oxigénio e de azoto em metodologias de micro-análise". Trabalho apresentado em 15º. ENQA – Encontro Nacional de Química Analítica e 3º CIAQA - Congresso Iberoamericano de Química Analítica, 2009.
  86. Ribeiro, Daniela (presenter); Couto, Diana; Gomes, Ana; Freitas, Marisa; Fernandes, Eduarda; Lima, Jose L.F.C.. "Scavenging activity for hypochlorous acid and peroxyl radical by sulfasalazine and its metabolites, sulfapyridine and 5-aminosalicylic acid". Trabalho apresentado em 1st National Meeting on Medicinal Chemistry, 2008.
Resumo em conferência
  1. Rufino, Ana Teresa; Lucas, Mariana; Silva, Artur M. S.; Fernandes, Eduarda; Ribeiro, Daniela. "2-Styrylchromones Inhibit IL-1ß-Induced Inflammatory Mediators’ Production in Human Fibroblast-like Synoviocytes". 2022.
    10.3390/ecmc2022-13183
  2. Lucas, Mariana; Freitas, Marisa; Silva, Artur M. S.; Fernandes, Eduarda; Ribeiro, Daniela. "2-Styrylchromones Modulate Prostaglandins Production through the Inhibition of COX-2". 2022.
    10.3390/ecmc2022-13232
  3. Pereira, Rui; Silva, Vera L. M.; Silva, Artur M. S.; Ribeiro, Daniela; Fernandes, Eduarda. "Synthesis and Chemical Reactivity of Novel Polyhydroxylated Bis-Chalcones". 2022.
    10.3390/ecmc2022-13473
  4. Rocha, Sónia; Ribeiro, Daniela; Silva, Vera L. M.; Artur M. S. Silva; Corvo, M. Luísa; Eduarda Fernandes; Freitas, Marisa. "New Insights on the inhibition of cyclooxygenases by 4-styrylpyrazoles: an enzymatic and human whole blood study". Trabalho apresentado em 14th Edition of the Nacional Organic Chemistry Meeting and 7th Edition of the Nacional Therapeutic Chemistry Meeting, 2022.
    Publicado • 10.3390/chemproc2022011001
  5. Lucas, Mariana; Freitas, Marisa; Joana L.C. Sousa; Artur M. S. Silva; Eduarda Fernandes; Ribeiro, Daniela. "Evaluation of COX-2 inhibitory activity by hydroxylated and methoxylated 2-styrylchromones". Trabalho apresentado em 14th Edition of the Nacional Organic Chemistry Meeting and 7th Edition of the Nacional Therapeutic Chemistry Meeting, Lisbon, 2022.
    Publicado
  6. Mariana Lucas; Freitas, Marisa; Zanchetta, Marco; Silva, Vera; Artur M. S. Silva; Eduarda Fernandes; Ribeiro, Daniela. "Cytotoxicity and anti-inflammatory potential of 2-styrylchromones". Trabalho apresentado em XVIth International Congress of Toxicology (ICT 2022) Uniting In Toxicology, Maastricht, 2022.
    Publicado
  7. Lucas, Mariana; Freitas, Marisa; Artur M. S. Silva; Fernandes, Eduarda; Ribeiro, Daniela. Autor correspondente: Ribeiro, Daniela. "Modulation of human neutrophils oxidative burst by hydroxylated 2-styrylchromones: the relevance of the catechol group". Trabalho apresentado em 1st International Electronic Conference on Biomedicine, 2021.
    Publicado • 10.3390/ECB2021-10283
  8. Ribeiro, Daniela. "Assessment of HOCl production in human blood: experimental optimization and proof of concept for the antioxidant activity of flavonoids in this complex matrix". Trabalho apresentado em SfRBM 27th Annual Conference, 2020.
    Publicado
  9. Ribeiro, Daniela; Freitas, Marisa; Carvalho, Félix; Fernandes, Eduarda. "The extended effects of thapsigargin on human neutrophils’ calcium pathways". Trabalho apresentado em SOT 58th Annual Meeting and ToxExpo, Baltimore, 2019.
    Publicado
  10. Nicola, Pedro (presenter); Freitas, Marisa; Rocha, Sónia; Carvalho, Félix; Fernandes, Eduarda; Ribeiro, Daniela. "Optimization of a synaptosomal model to study the effect of carotenoids in peroxynitrite - induced lipid peroxidation". Trabalho apresentado em YES (Young European Scientist) Meeting [Porto Biomed. J., 3 (3) (2018) PS106. ISSN: 2444-8672], Oporto, 2018.
    Publicado
  11. Ribeiro, Daniela (presenter); Sousa, Adelaide; Rocha, Sílvia; Freitas, Marisa; Fernandes, Eduarda. "ß-Carotene and its biological oxidation products: are they good modulators of pro-oxidant reactive species in human blood and neutrophils assay systems?". Trabalho apresentado em Meeting of the International HNE-Club and the University of Graz - Reactive Oxygen Species and Lipid Peroxidation in Human Health and Disease [Free Radical Bio. Med., 124 (2018) 574 - 575], Graz, 2018.
    Publicado
  12. Ribeiro, Daniela (presenter); Soares, Tânia; Rocha, Sónia; Sarraguça, Mafalda; Fernandes, Eduarda; Freitas, Marisa. "Optimization of experimental settings for the assessment of HOCl in human blood, using the fluorescent probe APF". Trabalho apresentado em 19th Biennial Meeting for the Society for Free Radical Research International (SFRRI) [Free Radic. Biol. Med., 129(Corrigendum) (2018) 620. DOI: 10.1016/j.freeradbiomed.2018.08.028], Lisbon, 2018.
    Publicado
  13. Proenca, Carina (presenter); Ribeiro, Daniela; Freitas, Marisa; Sousa, J.L.C.; Fernandes, P.A.; Fernandes, Eduarda. "Structure-related inhibition of protein tyrosine phosphatase 1B (PTP1B) by flavonoids". Trabalho apresentado em 22nd International Conference on Prevention of diabetes and complications [Pancreat. Disord. Ther., 7 (4) (Suppl) (2017) 44], London, 2017.
    Publicado
  14. Freitas, Marisa (presenter); Sousa, Adelaide; Ribeiro, Daniela; Fernandes, Eduarda. "Prediction of anti-diabetic activity of flavonoids targeting a-glucosidase". Trabalho apresentado em 22nd International Conference on Prevention of diabetes and complications [Pancreat. Disord. Ther., 7 (4) (Suppl) (2017) 25], London, 2017.
    Publicado • 10.4172/2165-7092-c1-008
  15. Ribeiro, Daniela (presenter); Freitas, Marisa; Tomé, S.M.; Silva, A.M.S.; Fernandes, Eduarda. "Flavonoids effects in proinflammatory signaling systems: in vitro structure/activity studies". Trabalho apresentado em Congresso de Química Orgânica e Química Terapêutica [Pharmaceuticals, 9 (1), 15 (2016) 17-18], Oporto, 2016.
    Publicado
  16. Proenca, Carina (presenter); Freitas, Marisa; Ribeiro, Daniela; Sousa, J.L.C.; Silva, A.M.S.; Fernandes, Eduarda. "In vitro antioxidant activity of novel 3-hydroxy-2-stytrylchromones as compared to 3-hydroxyflavones". Trabalho apresentado em Congresso de Química Orgânica e Química Terapêutica [Pharmaceuticals, 9 (1), 15 (2016) 32-33], Oporto, 2016.
    Publicado • 10.3390/ph9010015
  17. Ribeiro, D. (presenter); Kupski, L.; Furlong, E. Badiale; Freitas, M.; Fernandes, E.. "Pro-inflammatory and toxic effects of ochratoxin and ochratoxin a in human neutrophils". Trabalho apresentado em 51st Congress of the European Society of Toxicology (EUROTOX) [Toxicol. Lett., 238 (2S) (2015) S88], Oporto, 2015.
    Publicado • 10.1016/j.toxlet.2015.08.294
  18. Soares, T. (presenter); Ribeiro, D.; Fernandes, E.; Freitas, M.. "Size-dependent cytotoxicity of silver nanoparticles in human neutrophils". Trabalho apresentado em 51st Congress of the European Society of Toxicology (EUROTOX) [Toxicol. Lett., 238 (2S) (2015) S216], Oporto, 2015.
    Publicado • 10.1016/j.toxlet.2015.08.640
  19. Ribeiro, Daniela (presenter); Freitas, Marisa; Lima, José Luís Costa; Fernandes, Eduarda. "Flavonoids inhibit the production of cytokines/chemokines and induce apoptosis in human neutrophils". Trabalho apresentado em SFRR-Europe 2014 Meeting [Free Radic. Biol. Med., 75 (2014) S46], Paris, 2014.
    Publicado • 10.1016/j.freeradbiomed.2014.10.806
  20. Freitas, Marisa (presenter); Ribeiro, Daniela; Sara, Tomé M.; Artur, Silva M.S.; Fernandes, Eduarda. "Anti-inflammatory and pro-apoptotic activities of chlorinated flavonoids in human neutrophils". Trabalho apresentado em SFRR-Europe 2014 Meeting [Free Radic. Biol. Med., 75 (2014) S30], Paris, 2014.
    Publicado • 10.1016/j.freeradbiomed.2014.10.760
  21. Ribeiro, Alessandra Braga (presenter); Berto, Alessandra; Ribeiro, Daniela; Freitas, Marisa; Chisté, Renan Campos; Visentainer, Jesuí Vergílio; Fernandes, Eduarda. "Stem bark and flower extracts of Vismia cauliflora: modulation of oxidative burst in human neutrophils’ and inhibition of oxidative damage in human erythrocytes". Trabalho apresentado em SFRR-Europe 2014 Meeting [Free Radic. Biol. Med., 75 (2014) S45-S46], Paris, 2014.
    Publicado • 10.1016/j.freeradbiomed.2014.10.805
  22. Ribeiro, D. (presenter); Freitas, M.; Tomé, S.M.; Silva, A.M.S.; Porto, G.; Fernandes, E.. "A structure-activity relationship study of flavonoids as dual inhibitors of LOX and COX". Trabalho apresentado em SFRR - Europe 2013 Meeting [Free Radic. Biol. Med., 65 (S1) (2013) S47], Athens, 2013.
    Publicado • 10.1016/j.freeradbiomed.2013.08.075
  23. Ribeiro, D. (presenter); Freitas, M.; Tomé, S.M.; Silva, A.M.S.; Porto, G.; Fernandes, E.. "Flavonoids as modulators of human neutrophils oxidative burst". Trabalho apresentado em The 16th biennial meeting for the Society for Free Radical Research International (SFRRI) [Free Radic. Biol. Med., 53 (S1) (2012) S163-S164], London, 2012.
    Publicado • 10.1016/j.freeradbiomed.2012.08.343
  24. Ribeiro, Daniela (presenter); Alves, Andreia; Fernandes, Eduarda. "Actividade antioxidante de derivados da 3-hidroxiflavona em sistemas in vitro". Trabalho apresentado em IV Congresso Ibero-americano de Ciências Farmacêuticas [Rev. Port. Farm. LII (n.º 5) Suplemento (2011) 191. ISSN: 0484-811 X], Lisbon, 2011.
    Publicado
  25. Ribeiro, Daniela (presenter); Couto, Diana; Gomes, Ana; Freitas, Marisa; Fernandes, Eduarda; Lima, J.L.F.C.. "Scavenging activity for hypochlorous acid and peroxyl radical by sulfasalazine and its metabolites, sulfapyridine and 5-aminosalicylic acid". Trabalho apresentado em 1st National Meeting on Medicinal Chemistry [Rev. Port. Farm. LII (n.º 3) Suplemento (2008) 88. ISSN: 0484-811 X], Oporto, 2008.
    Publicado
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/11 Bis-chalcones: A new scaffold for novel and potent inhibitors of cyclooxygenase 2 XXVII Encontro Luso Galego de Química
2023/10 Polyhydroxy bis-chalcones: from synthesis to cyclization into novel flavonoids Webinar do Molecular Synthesis Research Group
2023/05 The importance of catechol and free hydroxy groups on chalcones' antioxidant activity 16.º Encontro de Investigação Jovem da U.Porto, Porto
2022/12 Pesquisa de novas moléculas com caráter anti-inflamatório em sangue humano Simpósio de Investigação da Faculdade de Farmácia da Universidade do Porto (SIFFUP)
2022/11 Anti-inflammatory activity of 2-styrylchromones in Human fibroblast like synoviocytes XXVI Encontro Galego-Portugués de Química
(Espanha)
2022/11 Polyhydroxylated bis-chalcones: potential new inhibitors of cyclooxygenase 2”. XXVI Encontro Galego-Portugués de Química XXVI Encontro Galego-Portugués de Química, Santiago de Compostela
(Espanha)
2022/11 New insights into the anti-inflammatory effects of 2-styrylchromones XXVI Encontro Galego-Portugués de Química, Santiago de Compostela
2021/05/31 Flavonoids and Their Styryl Derivatives as Promising Modulators of Pro-Oxidant and Proinflammatory Pathways 8th Molecules Webinar - New Trends of Flavonoids in Human Health
sciforum
2020/11 Discovery and optimization of new phenolic cinnamic acid derivatives as selective COX-2 inhibitors. Chemistry and structure-activity relationships IberPhenol International Conference
(Portugal)
2020/11 2-Styrylchromones versus flavonoids: which have the best anti-inflammatory activity? IberPhenol International Conference
(Portugal)
2020/01 Chalcones modulate the production of reactive species and NETs release by human neutrophils in normal and hyperglycemic conditions 13th National Organic Chemistry Meeting - 6th National Medicinal Chemistry Meeting
(Aveiro, Portugal)
2019/11 Chalcones as modulators of neutrophils oxidative burst, in physiological and hyperglycemic conditions XXV Encontro Galego-Portugués De Química, Santiago de Compostela
(Santiago de Compostela, Espanha)
2019/11 The potential antidiabetic effect of flavonoids through inhibition of fructose 1,6-bisphosphatase XXV Encontro Galego-Portugués De Química, Santiago de Compostela
(Santiago de Compostela, Espanha)
2019/11 Synaptosomes as membranar models to study the effects of carotenoids on lipid peroxidation XXV Encontro Galego-Portugués De Química, Santiago de Compostela
(Santiago de Compostela, Espanha)
2019/10 Desenvolvimento e aplicação de um modelo sinaptossomal para o estudo do efeito dos carotenoides na peroxidação lipídica I Simpósio Internacional de Nutrição
(Brasil)
2019/10 À descoberta de polifenóis com atividade anti-inflamatória V Simpósio Nordestino de Pós-Graduação em Química e Biotecnologia
(Brasil)
2019/05 2-Styrylchromones in the treatment of rheumatoid arthritis: a promising therapeutic alternative? Presentation of the scientific research project
School of Pharmacy, University of Nottingham (Nottingham, Reino Unido)
2018/11 Development and application of a synaptosomal model for the study of peroxynitrite - induced lipid peroxidation XXIV Encontro Luso-Galego de Química
(Oporto, Portugal)
2017/10 Structure-related inhibition of protein tyrosine phosphatase 1B (PTP1B) by flavonoids 22nd International Conference on Prevention of diabetes and complications
(London, Reino Unido)
2017/10 Prediction of anti-diabetic activity of flavonoids targeting a-glucosidase 22nd International Conference on Prevention of diabetes and complications
(London, Reino Unido)
2016/11 Arylxanthones with anti-inflammatory potential in celular systems XXII Encontro Luso-Galego Química
(Bragança, Portugal)
2016/06 Assessment of human neutrophils viability by multiple analytical approaches 8th Meeting of Analytical Chemistry Division of the Portuguese Chemical Society
(Lisbon, Portugal)
2015/12 Flavonoids effects in proinflammatory signaling systems: in vitro structure/activity studies Congresso de Química Orgânica e Química Terapêutica
(Oporto, Portugal)
2015/11 Chlorinated flavonoids are more effective than their parent compounds in the modulation of human neutrophils oxidative burst and lifespan XXI Encontro Galego-Portugués de Química
(Pontevedra, Espanha)
2015/11 The antioxidant activity of novel chromones and xanthones: a structure activity relationship XXI Encontro Galego-Portugués de Química
(Pontevedra, Espanha)
2013/11 Estudo de flavonoides como potenciais inibidores da enzima lipoxigenase XIX Encontro Galego-Portugués de Química
(Vigo, Espanha)
2013/11 Flavonoides clorados como potenciais moduladores do burst oxidativo de neutrófilos humanos XIX Encontro Galego-Portugués de Química
(Vigo, Espanha)
2013/06 Luminescence probes: study of the modulatory effect of flavonoids on oxidative burst in human neutrophils XXIII Encontro Nacional da SPQ
(Aveiro, Portugal)
2013/06 Effect of acetaminophen in human neutrohils’ oxidative burst and lifespan in vitro XXIII Encontro Nacional da SPQ
(Aveiro, Portugal)
2012/11 Flavonoids and Inflammation: a structure - activity relationship study 3º Encontro Nacional de Química Terapêutica
(Aveiro, Portugal)
2012/02 Antioxidant activity mediated by non-steroidal anti-inflammatory drugs of the anthranilic acid chemical group IJUP’12 5th meeting of young researchers of U. Porto
(Oporto, Portugal)
2011/11 Flavonóides - modeladores do burst oxidativo de neutrófilos humanos XVII Encontro Galego-Portugués de Química
(Pontevedra, Espanha)
2011/07 Inhibition of human neutrophil oxidative burst mediated by flavonoids XXII Encontro Nacional da SPQ / 8º Encontro do Grupo de Radicais Livres
(Braga, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2021/04 - Atual Synthesis of new chalcone and styrylchromone scaffolds as alternative drugs for inflammatory diseases treatment
Coorientador
Universidade do Porto Faculdade de Farmácia, Portugal

Universidade de Aveiro Departamento de Química, Portugal
2020/01 - Atual Development of an alternative therapeutic approach for rheumatoid arthritis based on styrylchromone scaffolds
Coorientador
 Programa Doutoral em Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/09 - 2023 Chromone derivatives as potential modulators of inflammatory response through their effects on human neutrophils function
Orientador
 Mestrado em Bioquímica (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal

Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/09 - 2022/09 Research into new molecules with anti-inflammatory activity
Coorientador
 Verão com Ciência (Iniciação científica)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/02 - 2022/07 Pesquisa de novas moléculas com atividade anti-inflamatória
Coorientador
 Ciências Farmacêuticas (Iniciação científica)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/02 - 2021/07 Pesquisa de novas moléculas com atividade anti-inflamatória
Orientador
 Project/Internship of the course FirstDegree in Biochemistry (Degree) (Licenciatura/Bacharelato)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
2021/02 - 2021/07 Screening of structurally-related flavonoids on cell viability and evaluation of effects on reactive species formation in an osteosarcoma in vitro model
Coorientador
 Internship (Licenciatura/Bacharelato)
Universidade do Porto Faculdade de Farmácia, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/01 - 2020 The therapeutic potential of 2-styrylchromones
Orientador
 Project/Internship of the course FirstDegree in Biochemistry (Degree) (Licenciatura/Bacharelato)
Universidade do Porto Faculdade de Farmácia, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/01 - 2020 Potential anti-inflammatory activity of chalcones: in vitro structure/activity studies of their effects in proinflammatory signalling systems
Coorientador
 PhD in Pharmaceutical Sciences (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/09 - 2019/02 Efeito dos carotenoides da dieta na peroxidação lipídica induzida pelo anião peroxinitrito
Orientador
 Project I from the course MSc in Pharmaceutical Sciences (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/02 - 2018/07 Desenvolvimento e aplicação de um modelo sinaptossomal para o estudo da peroxidação lipídica induzida pelo anião peroxinitrito
Orientador
 Project/Internship of the course First Degree in Biochemistry (Licenciatura/Bacharelato)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
2015/10 - 2017/11 Estimation of postmortem interval based on the cell death progression in biological fluids
Coorientador
 2nd Cycle of Studies in Forensic Sciences (Mestrado)
Universidade do Porto Faculdade de Medicina, Portugal
2017/02 - 2017/07 The effect of chalcones on human neutrophils' oxidative burst
Coorientador
 Project II from the course MSc in Pharmaceutical Sciences (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2018/11 - Atual Collaborator of the Institute for Health Metrics and Evaluation (IHME) at the University of Washington. The IHME involves a network of individual contributors with expertise in various areas to conduct global studies on disease, injury and risk factors - Global Burden of Diseases, Injuries, and Risk Factors (GBD). GBD corresponds to an approach to global descriptive epidemiology and a systematic scientific dynamic to quantify the comparative magnitude of health loss due to disease, injury and risk factors by age, gender and geography. Global Burden of Disease (GBD) - Institute for Health Metrics and Evaluation, Estados Unidos
2015/01 - 2016/02 Volunteer researcher in UCIBIO-REQUIMTE, the work was undertaken in the Applied Chemistry Laboratory, in FFUP. REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2015 - 2015 Collaboration, as a Service Provider, in 2015, in the writing, preparation and development of the project I&D Empresas: “GINDOURO – Desenvolvimento de um gin com identidade Duriense”, da Gran Cruz Porto - Sociedade Comercial de Vinhos Lda. This project, under the reference PT2020/I&DT Empresas PI/9072/2016, was financed by Fundo Europeu de Desenvolvimento Regional (FEDER), through the "Sistema de Incentivos à Investigação e Desenvolvimento Tecnológico - Projetos Individuais do COMPETE2020 - POCI". Gran Cruz Porto - Sociedade Comercial de Vinhos Lda, Portugal

Membro de associação

Nome da associação Tipo de participação
2018 - Atual Sociedade Portuguesa de Química Member.
2017 - Atual Society for Free Radical Research (SFRR) (Europe) Member.