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I am a truly committed and determined person, highly dedicated and motivated. I strive daily to address the challenges in my work and achieve successfully my goals. This allowed me to have success in my academic path. During my academic path, I have developed a solid analytical thinking due to the high requirements of the curricular program. At the moment, I am a PhD student working on the development of novel molecules with anticancer activity and I intend to deep my scientific knowledge and exploring innovation and entrepreneur activities. Pedro José Moreira Sobral. Concluiu o(a) Mestrado integrado em Integrated Masters degree in Pharmaceutical Sciences em 2018/09/18 pelo(a) Universidade de Coimbra Faculdade de Farmácia. Frequenta o(a) Doutoramento em Doutoramento em Ciências Farmacêuticas pelo(a) Universidade de Coimbra Faculdade de Farmácia desde 2020. É Investigador no(a) Fundação para a Ciência e a Tecnologia. Publicou 4 artigos em revistas especializadas. Participou em 18 evento(s). Recebeu 4 prémio(s) e/ou homenagens. Participa e/ou participou como Bolseiro de Doutoramento em 1 projeto(s) e Bolseiro de Investigação em 1 projeto(s). Atua na(s) área(s) de Ciências Médicas e da Saúde e Ciências Exatas com ênfase em Química com ênfase em Química Orgânica. Nas suas atividades profissionais interagiu com 14 colaborador(es) em coautorias de trabalhos científicos.
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Identification

Personal identification

Full name
Pedro José Moreira Sobral
Date of birth
1995/04/06
Gender
Male

Citation names

  • Pedro J. M. Sobral

Author identifiers

Ciência ID
001B-EB58-C8B2
ORCID iD
0000-0001-5202-4002
Researcher Id
F-9485-2019

Email addresses

  • pedrojmsobral@gmail.com (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences
  • Exact Sciences - Chemical Sciences - Organic Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Spanish; Castilian Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Education
Degree Classification
2020 - 2024
Ongoing
 Doutoramento em Ciências Farmacêuticas (Doutoramento)
Major in Química Farmacêutica
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/02 - 2020/06
Concluded
 Curso de Formação de Inglês do Quotidiano, nível Avançado II (Outros)
Universidade de Coimbra, Portugal
 18
2013/09/10 - 2018/09/18
Concluded
 Integrated Masters degree in Pharmaceutical Sciences (Mestrado integrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
"Internship Reports and Monograph entitled "Molecular Therapy in Neurodegenerative Diseases: rAAVs and Alzheimer's Disease" - Mark 18/20" (THESIS/DISSERTATION)
 16
2010 - 2013
Concluded
 Scientific-Humanistic course in Science and Technology (Ensino secundário)
Escola Secundária da Infanta D. Maria, Portugal
 17
Affiliation

Science

Category
Host institution 		Employer
2021/07/01 - Current Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
2018/11/19 - 2020/03/31 Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2020/09/01 - 2021/06/30 Invited Assistant (University Teacher) Universidade de Coimbra Faculdade de Farmácia, Portugal

Others

Category
Host institution 		Employer
2018/05/02 - 2018/07/31 Curricular Internship in Drug Regulatory Affairs INFARMED, I.P., Portugal
Direcção de Avaliação de Medicamentos - Unidade de Introdução no Mercado, Portugal
2018/01/08 - 2018/04/27 Curricular Internship in Community Pharmacy Farmácia São Sebastião, Portugal
2017/07/03 - 2017/07/26 Extracurricular Internship in Community Pharmacy Farmácia Estádio, Portugal
Projects

Grant

Designation Funders
2021/07/01 - Current Preparation of novel fluorinated ent-kaurane-type diterpenoid derivatives and evaluation of their antiproliferative activity
DFA/BD/4950/2020
PhD Student Fellow
Universidade de Coimbra Faculdade de Farmácia, Portugal

Universidade de Coimbra Centro de Química de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universitat Autònoma de Barcelona Departament de Bioquímica i Biologia Molecular, Spain
Fundação para a Ciência e a Tecnologia
Ongoing
2018/11/19 - 2020/03/31 Small proteasome inhibitory molecules: a step forward in the discovery of antitumor drugs
PTDC/QEQ-MED/7042/2014
Research Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Conference abstract
  1. Pedro J. M. Sobral. "Novel semisynthetic A-ring-cleaved glycyrrhetinic acid derivatives as potential anticancer agents". Paper presented in 15th National Organic Chemistry Meeting & 8th National Medicinal Chemistry Meeting, Faro, 2024.
    Published
  2. Pedro J. M. Sobral. "Synthesis and Cytotoxic Evaluation of Novel Madecassic Acid Derivatives". Paper presented in X Congresso Iberoamericano em Ciências Farmacêuticas, Coimbra, 2023.
    Published
  3. Pedro J. M. Sobral. "Síntese e Avaliação Citotóxica de Novos Derivados do Ácido Madecássico". Paper presented in 5º Encontro Nacional de Jovens Investigadores em Oncologia (5º ENJIO), Porto, 2023.
    Published
  4. Pedro J. M. Sobral. "Synthesis of novel madecassic acid derivatives and evaluation of their anticancer activity". Paper presented in 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting, Costa da Caparica, 2022.
    Published
  5. Pedro J. M. Sobral. "Novel A-ring cleaved glycyrrhetinic acid derivatives: Synthesis and evaluation of antiproliferative activity". Paper presented in The 7th International Electronic Conference on Medicinal Chemistry, 2021.
    Published
  6. Pedro J. M. Sobral. "Novel semisynthetic derivatives of madecassic acid as potential anticancer agents". Paper presented in ACS Fall 2021, Atlanta, 2021.
    Published
  7. Pedro J. M. Sobral. "Polyphenols as natural leads for drug discovery. Selective chemoenzymatic reactions.". Paper presented in IberPhenol - International Conference, Coimbra, 2020.
    Published
  8. Pedro J. M. Sobral. "Rutin and naringin as natural leads for drug discovery. Biocatalytic modifications to achieve novel bioactive compounds.". Paper presented in IberPhenol - International Conference, Coimbra, 2020.
    Published
  9. Pedro J. M. Sobral. "Novel Semisynthetic Derivatives of Madecassic Acid with Anticancer Activity". Paper presented in 13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT), Aveiro, 2020.
    Published
  10. Pedro J. M. Sobral. "Novel A-Ring Cleaved Glycyrrhetinic Acid Derivatives with Antiproliferative Activity". Paper presented in 13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT), Aveiro, 2020.
    Published
Conference poster
  1. Pedro J. M. Sobral. "Novel semisynthetic A-ring-cleaved glycyrrhetinic acid derivatives as potential anticancer agents". Paper presented in 15th National Organic Chemistry Meeting & 8th National Medicinal Chemistry Meeting, 2024.
  2. Pedro J. M. Sobral. "Synthesis and Cytotoxic Evaluation of Novel Madecassic Acid Derivatives". Paper presented in X Congresso Iberoamericano em Ciências Farmacêuticas, 2023.
  3. Pedro J. M. Sobral. "Síntese e Avaliação Citotóxica de Novos Derivados do Ácido Madecássico". Paper presented in 5º Encontro Nacional de Jovens Investigadores em Oncologia (5º ENJIO), 2023.
  4. Pedro J. M. Sobral. "Synthesis of novel madecassic acid derivatives and evaluation of their anticancer activity". Paper presented in 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting, 2022.
  5. Pedro J. M. Sobral. "Novel A-ring cleaved glycyrrhetinic acid derivatives: Synthesis and evaluation of antiproliferative activity". Paper presented in The 7th International Electronic Conference on Medicinal Chemistry, 2021.
  6. Pedro J. M. Sobral. "Novel semisynthetic derivatives of madecassic acid as potential anticancer agents". Paper presented in ACS Fall 2021, 2021.
  7. Pedro J. M. Sobral. "Rutin and naringin as natural leads for drug discovery. Biocatalytic modifications to achieve novel bioactive compounds.". Paper presented in IberPhenol - International Conference, 2020.
  8. Pedro J. M. Sobral. "Novel A-Ring Cleaved Glycyrrhetinic Acid Derivatives with Antiproliferative Activity". Paper presented in 13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT), 2020.
  9. Pedro J. M. Sobral. "Novel Semisynthetic Derivatives of Madecassic Acid with Anticancer Activity". Paper presented in 13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT), 2020.
  10. Pedro J. M. Sobral. "Synthesis and Antiproliferative Activity of Novel A-Ring Cleaved Glycyrrhetinic Acid Derivatives". Paper presented in CIBB Meeting 2019, 2019.
  11. Pedro J. M. Sobral. "Madecassic Acid Derivatives as Potential Anticancer Agents: Synthesis and Cytotoxic Evaluation". Paper presented in CIBB Meeting 2019, 2019.
Journal article
  1. Pedro J. M. Sobral. "Synthesis and Cytotoxic Evaluation of Novel Madecassic Acid Derivatives". Acta Farmacêutica Portuguesa - X Congresso Iberoamericano de Ciências Farmacêuticas (2023): https://actafarmaceuticaportuguesa.com/index.php/afp/issue/view/30.
    Published
  2. Pedro J. M. Sobral; Vicente, André T. S.; Salvador, Jorge A. R.. Corresponding author: Salvador, Jorge A. R.. "Recent advances in oridonin derivatives with anticancer activity". Frontiers in Chemistry 11 (2023): http://dx.doi.org/10.3389/fchem.2023.1066280.
    Published • 10.3389/fchem.2023.1066280
  3. Judite RM Coimbra; Pedro J. M. Sobral; Armanda E Santos; Paula I. Moreira; Jorge AR Salvador. "An overview of glutaminyl cyclase inhibitors for Alzheimer's disease". Future Medicinal Chemistry 11 24 (2019): 3179-3194. https://doi.org/10.4155/fmc-2019-0163.
    Published • 10.4155/fmc-2019-0163
  4. Balakrishna, Avula*; Aguiar, António*; Sobral, Pedro J. M.*; Wani, Mohmmad Younus; Almeida e Silva, Joana; Sobral, Abilio J. F. N.. "Paal-Knorr synthesis of pyrroles: from conventional to green synthesis". Catalysis Reviews 61 1 (2018): 84-110. http://dx.doi.org/10.1080/01614940.2018.1529932.
    Published • 10.1080/01614940.2018.1529932
Thesis / Dissertation
  1. Pedro J. M. Sobral. "Internship Reports and Monograph entitled "Molecular Therapy in Neurodegenerative Diseases: rAAVs and Alzheimer's Disease" - Mark 18/20". Master, Universidade de Coimbra Faculdade de Farmácia, 2018. http://hdl.handle.net/10316/84380.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2020/01 Evaluation of the proteasomal inhibitory activity of the previously synthesized novel boronic acid derivatives Group Meeting
Faculdade de Farmácia da Universidade de Coimbra (Coimbra, Portugal)
2019/05 Chemical synthesis of the best previously designed novel boronic acid derivatives Group Meeting
Faculdade de Farmácia da Universidade de Coimbra (Coimbra, Portugal)
2019/01 Virtual library of novel boronic acid derivatives aiming to improve proteasomal inhibitory activity, selectivity, safety and pharmacokinetic properties Group Meeting
Faculdade de Farmácia da Universidade de Coimbra (Coimbra, Portugal)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023 - 2033 Pharmaceutics - 3D and 4D Printing in Pharmaceutics
Congress
 Pharmaceutics - 3D and 4D Printing in Pharmaceutics
Multidisciplinary Digital Publishing Institute AG, Switzerland
2024/01/22 - 2024/01/24 15th National Organic Chemistry Meeting (15ENQO) & 8th National Medicinal Chemistry Meeting (8ENQT)
Conference
 15th National Organic Chemistry Meeting & 8th National Medicinal Chemistry Meeting
Sociedade Portuguesa de Química, Portugal
2023/10/26 - 2023/10/28 X Congresso Iberoamericano em Ciências Farmacêuticas
Congress
 X Congresso Iberoamericano em Ciências Farmacêuticas
2023/09/22 - 2023/09/22 5º Encontro Nacional de Jovens Investigadores em Oncologia (5º ENJIO)
Conference
 5º Encontro Nacional de Jovens Investigadores em Oncologia (5º ENJIO)
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
2022/04/20 - 2022/04/22 14th National Organic Chemistry Meeting (14ENQO) and the 7th National Medicinal Chemistry Meeting (7ENQT)
Congress
 14th National Organic Chemistry Meeting (14ENQO) and the 7th National Medicinal Chemistry Meeting (7ENQT)
Sociedade Portuguesa de Química, Portugal
2021/11/01 - 2021/11/30 The 7th International Electronic Conference on Medicinal Chemistry (ECMC 2021)
Conference
 The 7th International Electronic Conference on Medicinal Chemistry (ECMC 2021)
2020/01/15 - 2020/01/17 13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT)
Congress
 13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT)
Sociedade Portuguesa de Química, Portugal
2020 - 2020 IberPhenol - International Conference (Abstracts accepted, Conference postponed due to Covid-19 pandemic)
Conference
 IberPhenol - International Conference
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/12/19 - 2019/12/20 CIBB Meeting 2019
Congress
 CIBB Meeting 2019
Centre for Innovative Biomedicine and Biotechnology (CIBB), Portugal
2019/11/15 - 2019/11/15 1st Annual Meeting in Pharmaceutical Sciences
Congress
 1st Annual Meeting in Pharmaceutical Sciences
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/10/04 - 2019/10/04 Researcher Academy On Campus - "How to Get Published"
Seminar
 Researcher Academy On Campus - "How to Get Published"
Elsevier Inc, United States
2019/09/12 - 2019/09/12 Web of Science Training
Seminar
 Web of Science Training
Clarivate Analytics Inc, United States

Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2018/10/26 - 2018/10/26 Cancro: A Intervenção do Farmacêutico
Seminar
 Cancro: A Intervenção do Farmacêutico
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro, Portugal
2018/09/27 - 2018/09/28 First Drugs R&D PhD Symposium - Translational Science: From Academia to Industry
Congress
 First Drugs R&D PhD Symposium - Translational Science: From Academia to Industry
Universidade de Coimbra, Portugal
2018/01/03 - 2018/01/05 PharmCareer 2018
Congress
 PharmCareer 2018
Núcleo de Estudantes de Farmácia, Faculdade de Farmácia da Universidade de Coimbra, Portugal
2017/12/18 - 2017/12/18 Formação SIFARMA
Seminar
 Formação SIFARMA
Núcleo de Estudantes de Farmácia, Faculdade de Farmácia da Universidade de Coimbra, Portugal
2016/11/10 - 2016/11/11 X Congresso Científico do NEF/AAC - Doenças Raras & Medicamentos Órfãos - Acesso À Inovação Terapêutica
Congress
 X Congresso Científico do NEF/AAC- Doenças Raras & Medicamentos Órfãos – Acesso À Inovação Terapêutica
Núcleo de Estudantes de Farmácia, Faculdade de Farmácia da Universidade de Coimbra, Portugal
2013/06/21 - 2013/06/26 Trainee in Chemical Engineering
Workshop
 5ª Edição da Universidade de Verão da Universidade de Coimbra
Universidade de Coimbra, Portugal

Association member

Society Organization name Role
2020/07 - Current Group for the Promotion of Pharmaceutical chemistry in Academia (GP2A) Portuguese National Point of Contact (NPC)
2019/11/02 - Current Sociedade Portuguesa de Química (SPQ) Nº de Sócio Activo - 6089

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021/02/01 - 2021/08/01 Química Farmacêutica II Mestrado Integrado em Ciências Farmacêuticas (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/02/01 - 2021/08/01 Toxicologia e Análises Toxicológicas Mestrado Integrado em Ciências Farmacêuticas (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/02/01 - 2021/08/01 Química Orgânica e Biomolecular Licenciatura em Farmácia Biomédica (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/09/01 - 2021/02/01 Metodologias Laboratoriais Licenciatura em Ciências Bioanalíticas (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/09/01 - 2021/02/01 Química Biorgânica Licenciatura em Ciências Bioanalíticas (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/09/01 - 2021/02/01 Química Orgânica II Mestrado Integrado em Ciências Farmacêuticas (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2024/07/04 - 2024/07/04 Carbohydrate Polymers (1879-1344) Elsevier
2024/02/03 - 2024/02/03 Materials Science and Engineering: B (1873-4944) Elsevier
2024 - 2024 Heliyon (2405-8440) Elsevier
2024 - 2024 Ecotoxicology and Environmental Safety (1090-2414) Elsevier
2023/09/19 - 2023/09/19 Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (1873-3557) Elsevier
2023/05/24 - 2023/05/24 Polycyclic Aromatic Compounds (1563-5333) Taylor & Francis
2023/02/22 - 2023/02/22 Inorganic Chemistry Communications (1879-0259) Elsevier

Mentoring / Tutoring

Topic Student name
2022/05 - 2022/07 Co-orientation of Integrated Master's Degree students of Pharmaceutical Sciences on Curricular Internship Integrated Master's Degree students of Pharmaceutical Sciences
2021/09 - 2022/02 Co-orientation of Erasmus+ Students Erasmus+ Students
2020/02 - 2020/05 Co-orientation of Integrated Master's Degree students of Pharmaceutical Sciences on Curricular Internship Integrated Master's Degree students of Pharmaceutical Sciences
2019/02 - 2019/05 Co-orientation of Integrated Master's Degree students of Pharmaceutical Sciences on Curricular Intership Integrated Master's Degree students of Pharmaceutical Sciences
Distinctions

Award

2024 15th National Organic Chemistry Meeting (15ENQO) & 8th National Medicinal Chemistry Meeting (8ENQT) Flash Poster Presentation Award
Sociedade Portuguesa de Química, Portugal
2023 X Congresso Iberoamericano em Ciências Farmacêuticas Best Pharmaceutical Chemistry Poster Award
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021 ECMC-7 Best Poster Award
Multidisciplinary Digital Publishing Institute AG, Switzerland
2014 The 3% Best Students Award
Universidade de Coimbra, Portugal