???global.info.a_carregar???
Identification

Personal identification

Full name
CARLA FILIPA SIMÕES HENRIQUES

Citation names

  • Simões-Henriques, Carla

Author identifiers

Ciência ID
001D-1005-4FE6
ORCID iD
0000-0003-1030-6065

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Behavioural Sciences Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Genetics and Heredity
  • Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Proficiency (C2) Proficiency (C2) Advanced (C1) Advanced (C1)
Education
Degree Classification
2019/09 - 2027
Ongoing
Medicine (Mestrado integrado)
Universidade de Lisboa Faculdade de Medicina, Portugal
2018/03/01 - 2024/11/25
Concluded
Integrative Biology and Biomedicine (Doutoramento)
Instituto Gulbenkian de Ciência, Portugal
"The genetic architecture of social and asocial learning in Drosophila melanogaster" (THESIS/DISSERTATION)
2019/07/01 - 2019/07/05
Concluded
Introduction to the Statistical Analysis of Genome-wide Association Studies - short course. (Outros)
Imperial College London, United Kingdom
2019/02 - 2019/02
Concluded
The Gulbenkian Training Programme in Bioinformatics (GTPB) - Entry Level Bioinformatics (Outros)
Instituto Gulbenkian de Ciência, Portugal
2018/10/01 - 2018/10/04
Concluded
IGC's Practical Course on Laboratory Animal Science in Mouse and Zebrafish. (Following EU recommendations for Functions A + D in Laboratory Animal Science). (Outros)
Instituto Gulbenkian de Ciência, Portugal
2018/09 - 2018/09
Concluded
SPCAL 20h Theoretical Course on Laboratory Animal Sciences - ONLINE (Following FELASA recommendations for Category B) (Outros)
Instituto Gulbenkian de Ciência, Portugal
2015/09 - 2017/09
Concluded
Biomedical Research (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
"Gender dimorphism of microglia morphology: adenosine and testosterone as putative modulators in transgender microglia experiments" (THESIS/DISSERTATION)
18/20
2011/09 - 2015/09
Concluded
Biochemistry (Licenciatura)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
13/20
Affiliation

Science

Category
Host institution
Employer
2024/10/31 - Current Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2023/09/01 - 2024/08/31 Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2018/03/01 - 2023/08/31 Research Trainee (Research) Gulbenkian Institute for Molecular Medicine, Portugal
Gulbenkian Institute for Molecular Medicine, Portugal
Projects

Grant

Designation Funders
2024/10/31 - Current CiNTech - technological hub for innovation, translation and industrialization of complex injectable drugs
Research Fellow
Universidade de Coimbra, Portugal
Ongoing
2023/09/01 - 2024/08/31 DietNObrain - Acoplamento neurovascular como biomarcador e alvo para melhoria cognitiva no envelhecimento e na demência vascular através de intervenção dietética inovadora suportada pela bioactivação de nitrato a óxido nítrico: um estudo translacional
2022.05454.PTDC
Research Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
2022/05 - 2022/07 The social fly: genetic architecture for social learning neural circuits in Drosophila melanogaster A mosca social: arquitectura genética dos circuitos neurais associados à aprendizagem social em Drosophila melanogaster
Provided by PTCRIS: COVID/BD/152638/2022
PhD Student Fellow
Instituto Gulbenkian de Ciência, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/03 - 2022/04 The social fly: genetic architecture for social learning neural circuits in Drosophila melanogaster A mosca social: arquitectura genética dos circuitos neurais associados à aprendizagem social em Drosophila melanogaster
Provided by PTCRIS: PD/BD/138178/2018
PhD Student Fellow
Instituto Gulbenkian de Ciência, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing

Other

Designation Funders
2016/06 - 2017/07
POCI-01-0145-FEDER-007440
CENTRO-01-0145-FEDER-000008: BrainHealth 2020
Master Student
Outputs

Publications

Conference poster
  1. Simões-Henriques, Carla; Marcos, J.; Sucena, E.; Vasconcelos, Maria Luísa; Varela, SAM; Oliveira, Rui F.. "Genetic architecture of social and asocial learning in Drosophila melanogaster". Paper presented in International Congress for Neuroethology 2022, 2022.
  2. Simões-Henriques, Carla; Marcos, J.; Sucena, E.; Vasconcelos, Maria Luísa; Varela, SAM; Oliveira, Rui F.. "A specialized genetic architecture for social learning in Drosophila melanogaster". Paper presented in 13th FENS Forum of Neuroscience, 2022.
  3. Simões-Henriques, Carla; Marcos, J.; Sucena, E.; Vasconcelos, Maria Luísa; Varela, SAM; Oliveira, Rui F.. "The genetics of social and asocial learning in Drosophila melanogaster". Paper presented in Ciência 2022 – Science and Technology in Portugal Summit, 2022.
  4. Simões-Henriques, Carla; Marcos, J.; Sucena, E.; Vasconcelos, Maria Luísa; Varela, SAM; Oliveira, Rui F.. "Functional specialization of social and asocial learnings in Drosophila melanogaster". Paper presented in 23rd EMBL PhD Symposium: The Big Picture: Zooming into Life, 2021.
  5. Simões-Henriques, Carla; Marcos, J.; Sucena, E.; Vasconcelos, Maria Luísa; Varela, SAM; Oliveira, Rui F.. "Functional specialization of social and asocial learnings in Drosophila melanogaster". Paper presented in 8 th Annual Portuguese Drosophila Meeting, 2021.
  6. Simões-Henriques, Carla; Marcos, J.; Sucena, E.; Vasconcelos, Maria Luísa; Varela, SAM; Oliveira, Rui F.. "Functional specialization of social and asocial learnings". Paper presented in Brain & Mind Symposium 2021, 2021.
  7. Simões-Henriques, Carla; Marcos, J.; Sucena, E.; Vasconcelos, Maria Luísa; Varela, SAM; Oliveira, Rui F.. "The genetic architecture of social and asocial learning in Drosophila melanogaster". Paper presented in XVII Congresso da Sociedade Portuguesa de Etologia, 2020.
  8. Simões-Henriques, Carla; Varela, SAM; Sucena, E.; Oliveira, Rui F.. "Genetic architecture of social and asocial learning in Drosophila melanogaster". Paper presented in XVI Congresso da Sociedade Portuguesa de Etologia, 2019.
  9. Simões-Henriques, Carla; Varela, SAM; Sucena, E.; Oliveira, Rui F.. "Genetic architecture of social and asocial learning in Drosophila melanogaster". Paper presented in XV Encontro Nacional de Biologia Evolutiva, 2019.
  10. Simões-Henriques, Carla; Varela, SAM; Sucena, E.; Oliveira, Rui F.. "Genetic architecture for social learning in Drosophila melanogaster". Paper presented in XVI Meeting of Portuguese Society for Neuroscience, 2019.
  11. Simões-Henriques, Carla; Ana Rita Gonçalves Gaspar; Almeida, I.; Carlos Alberto Fontes Ribeiro; António Francisco Rosa Gomes Ambrósio; Catarina Alexandra Reis Vale Gomes. "Testosterone masculinizes microglia morphology in the prefrontal cortex and anxious-like behaviour: a fundamental study of an organizational effect". Paper presented in The Lancet Summit: Inflammation and Immunity in Disorders of the Brain and Mind, 2018.
  12. Simões-Henriques, Carla; MIGUEL MARIA RESTOLHO MATEUS PINHEIRO; Ana Rita Gonçalves Gaspar; Duarte, J.M.; Helena Pinheiro; Carlos Alberto Fontes Ribeiro; Rodrigo Antunes Cunha; António Francisco Rosa Gomes Ambrósio; Catarina Alexandra Reis Vale Gomes. "Brain region and gender-specific microglia subpopulations: an organizational effect of adenosine A2A receptor in microglia morphology". Paper presented in 11th FENS Forum of Neuroscience, 2018.
  13. Simões-Henriques, Carla; Ana Rita Gonçalves Gaspar; Almeida, I.; Carlos Alberto Fontes Ribeiro; António Francisco Rosa Gomes Ambrósio; Catarina Alexandra Reis Vale Gomes. "Correlating anxious-like behaviour with microglia morphology in the prefrontal cortex in a gender-specific manner: an organizational effect of testosterone". Paper presented in 11th FENS Forum of Neuroscience, 2018.
  14. Simões-Henriques, Carla; MIGUEL MARIA RESTOLHO MATEUS PINHEIRO; Ana Rita Gonçalves Gaspar; Duarte, J.M.; Helena Pinheiro; Carlos Alberto Fontes Ribeiro; Paula Margarida Gomes Canas; et al. "Adenosine A2A receptor orchestrates different morphological remodeling of microglia subpopulations". Paper presented in III Symposium of the Portuguese Glial Network, 2018.
  15. Almeida, I.; Ana Catarina Rodrigues Neves; Simões-Henriques, Carla; António Francisco Rosa Gomes Ambrósio; Carlos Alberto Fontes Ribeiro; Catarina Alexandra Reis Vale Gomes. "Regulation of microglia by glucocorticoids: comparative analysis between dexamethasone and betamethasone". Paper presented in Microglia EMBO workshop, 2018.
  16. Ferrer, F.; Ana Rita Gonçalves Gaspar; Simões-Henriques, Carla; Duarte, J.M.; Caetano, L.; Patrício, P.; Carina Soares-Cunha; et al. "Microglial modification in neuropsychiatric pathology secondary to prenatal exposure to glucocorticoids". Paper presented in VII IN4MED, 2018.
  17. Simões-Henriques, Carla; Ana Rita Gonçalves Gaspar; Almeida, I.; Carlos Alberto Fontes Ribeiro; António Francisco Rosa Gomes Ambrósio; Catarina Alexandra Reis Vale Gomes. "Organizational effect of testosterone: masculinizing anxious-like behaviour and microglia morphology in the prefrontal cortex". Paper presented in III Scientific meeting of the Chemistry Student’s Nucleus of the Coimbra Academic Association, 2018.
  18. Almeida, I.; Ana Catarina Rodrigues Neves; Simões-Henriques, Carla; António Francisco Rosa Gomes Ambrósio; Carlos Alberto Fontes Ribeiro; Catarina Alexandra Reis Vale Gomes. "In vitro effects of dexamethasone and betamethasone on microglia: structure-activity correlation study". Paper presented in III Scientific meeting of the Chemistry Student’s Nucleus of the Coimbra Academic Association, 2018.
  19. Simões-Henriques, Carla; Duarte, J.; Helena Pinheiro; Ana Rita Gonçalves Gaspar; Almeida, I.; Patrício, P.; ANTÓNIO MARIA RESTOLHO MATEUS PINHEIRO; et al. "Chronic blockade of adenosine A2A receptors: gender-specific reprogramming of microglia morphology in the PFC". Paper presented in XV Portuguese Society for Neuroscience meeting, 2017.
  20. MIGUEL MARIA RESTOLHO MATEUS PINHEIRO; Ana Rita Gonçalves Gaspar; Helena Pinheiro; Simões-Henriques, Carla; Duarte, J.M.; Rodrigo Antunes Cunha; António Francisco Rosa Gomes Ambrósio; Catarina Alexandra Reis Vale Gomes. "Portraying gender differences in microglia morphology across brain regions". Paper presented in XV Portuguese Society for Neuroscience meeting, 2017.
Journal article
  1. Carla Filipa Simões-Henriques; A. Catarina Rodrigues-Neves; Fábio J. Sousa; Rita Gaspar; Inês Almeida; Filipa I. Baptista; António F. Ambrósio; Catarina A. Gomes. "Neonatal testosterone voids sexually differentiated microglia morphology and behavior". Frontiers in Endocrinology 14 (2023): http://dx.doi.org/10.3389/fendo.2023.1102068.
    10.3389/fendo.2023.1102068
  2. Carla Simões-Henriques; Miguel Mateus-Pinheiro; Rita Gaspar; Helena Pinheiro; Joana Mendes Duarte; Filipa I. Baptista; Paula M. Canas; et al. "Microglia cytoarchitecture in the brain of adenosine A 2A receptor knockout mice: Brain region and sex specificities". European Journal of Neuroscience (2020): https://doi.org/10.1111/ejn.14561.
    10.1111/ejn.14561
Thesis / Dissertation
  1. "The genetic architecture of social and asocial learning in Drosophila melanogaster". PhD, Gulbenkian Institute for Molecular Medicine, 2024.
  2. "Gender dimorphism of microglia morphology: adenosine and testosterone as putative modulators in transgender microglia experiments". Master, Universidade de Coimbra Faculdade de Medicina, 2017. http://hdl.handle.net/10316/81417.

Artistic / Performance

Artistic exhibition
  1. Simões-Henriques, Carla; Ambrósio, A.F.; Gomes, Catarina. MicroScience Photo Gallery - "The Beauty in our Cells" in the context of the Brain Awareness Week 2018. 2018.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/07 A specialized genetic architecture for social learning in Drosophila melanogaster. International Society for Behavioral Ecology Congress 2022
International Society for Behavioral Ecology (Stockholm, Sweden)
2022/07 A specialized genetic architecture for social learning in Drosophila melanogaster European Conference on Behavioural Biology: ECBB 22 – ALL OF LIFE IS SOCIAL
Association for the Study of Animal Behaviour (Groningen, Netherlands)
2022/04 A specialized genetic architecture for social learning in Drosophila melanogaster 12th ITQB Nova PhD Students' Meeting
Instituto de Tecnologia Química e Biológica António Xavier (Oeiras, Portugal)
2021/12 Functional specialization of social and asocial learnings in Drosophila melanogaster XVII Annual Meeting of the Portuguese Association for Evolutionary Biology
Associação Portuguesa de Biologia Evolutiva (Online)
2021/10 Functional specialization of social learning in Drosophila melanogaster XVIII Conference of the Portuguese Society of Ethology- SPE 2021
Sociedade Portuguesa de Etologia (Online)
2020/12 The genetic architecture of social and asocial learning in Drosophila melanogaster XVI Encontro Nacional de Biologia Evolutiva
Associação Portuguesa de Biologia Evolutiva (Online)
2019/05 Genetic architecture for social learning in Drosophila melanogaster XVI Meeting of Portuguese Society for Neuroscience
Sociedade Portuguesa de Neurociências (Lisbon, Portugal)
2018/02 Gender-specific organizational and activational effects of adenosine A2A receptor in microglia morphology in the prefrontal cortex IV Biochemists National Meeting
Associação Nacional de Bioquímicos (ANBIOQ) (Lisbon, Portugal)
2018/02 Organizational effect of testosterone: masculinizing anxious-like behaviour and microglia morphology in the prefrontal cortex III Scientific meeting of the Chemistry Student's Nucleus of the Coimbra Academic Association
Chemistry Student's Nucleus of the Coimbra Academic Association (Coimbra, Portugal)
2018/02 In vitro effects of dexamethasone and betamethasone on microglia: structure-activity correlation study III Scientific meeting of the Chemistry Student's Nucleus of the Coimbra Academic Association
Chemistry Student's Nucleus of the Coimbra Academic Association (Coimbra, Portugal)
2018/02 Masculinizing female anxious-like behaviour: organizational instructions in transgender experiments XLVIII Meeting of the Portuguese Society for Pharmacology
Portuguese Society for Pharmacology (Lisbon, Portugal)
2018/02 Effects of Dexamethasone and Betamethasone on brain microglia: structure-activity correlation study XLVIII Meeting of the Portuguese Society for Pharmacology
Portuguese Society for Pharmacology (Lisbon, Portugal)
2017/05 Chronic blockade of adenosine A2A receptors: gender-specific reprogramming of microglia morphology in the PFC XV Portuguese Society for Neuroscience meeting
Portuguese Society for Neuroscience (Braga, Portugal)
2017/02 Gender determination of microglia morphology in the prefrontal cortex: born similar, age differently XLVII Meeting of the Portuguese Society for Pharmacology
Portuguese Society for Pharmacology (Coimbra, Portugal)

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2017/10/09 - 2017/10/09 Assistance in a theoretical lecture of the discipline Biology and Physiology of Aging, at the Faculty of Psychology of the University of Coimbra. (Licenciatura) Universidade de Coimbra Faculdade de Psicologia e de Ciências da Educação, Portugal

Mentoring / Tutoring

Topic Student name
2019/02 - 2019/06 Tuition of the student Sara Santos from the BSc in Evolutionary and Developmental Biology, in the context of a laboratorial rotation for the the curricular unit Oriented Study. Sara Santos
2019/02 - 2019/06 Tuition of the student Gonçalo Silva from the BSc in Evolutionary and Developmental Biology, in the context of a laboratorial rotation for the the curricular unit Oriented Study. Gonçalo Silva
2018/02 - 2018/02 Tuition of students in a Laboratorial Rotation related to the Master in Biomedical Research, Faculty of Medicine of the University of Coimbra. Group of students
2017/09 - 2017/10 Tuition of students in the curricular unit Cell Regulation from the Master in Biomedical Research, Faculty of Medicine of the University of Coimbra. Group of students
2016/06 - 2017/07 Tuition of the student Francisco Ferrer in the context of the curricular unit Applied Research IV, from the 3rd year of the Integrated Master in Medicine, Faculty of Medicine of the University of Coimbra. Francisco Ferrer
Distinctions

Award

2021 Prize Vitor Almada: best oral communication at XVIII Conference of the Portuguese Society of Ethology- SPE 2021.
Portuguese Society of Ethology, Portugal
2018 Best oral communication at IV Biochemists National Meeting.
Associação Nacional de Bioquímicos (ANBIOQ), Portugal
2008 Best student prize of the 2nd and 3rd cycles' school of Avelar in the 9th grade. Avelar, Leiria, Portugal.
Municipality of Ansião, Portugal
2008 Best student prize of the 2nd and 3rd cycles' schools of the municipality of Ansião in the 9th grade. Ansião, Leiria, Portugal.
Rotary Club de Ansião, Portugal