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Dr. Cristiana de Carvalho has finished her master degree in Pharmaceutical Sciences in 2012 through the faculty of Pharmacy of University of Porto with the GPA of 15 (in 20). She later concluded her PhD degree in Tissue Engineering, Regenerative Medicine and Stem Cells in 3Bs Research group, in 2019/10/11, in Neurosciences, namely in peripheral nerve regeneration, with the highest qualitative grade "Menção honrosa de Muito Bom". Dr. Cristiana was immediately awarded with a postdoctoral fellowship under the project 2IQBIONEURO, which articulates a network of R&D in biological chemistry for the treatment of neurological diseases, specifically continuing her research path of neuronal research. During her PhD, she was a visiting/invited researcher at Neuroanatomy department in Hannover Medical School (Germany) and later at New Jersey Center for Biomaterials at Rutgers University. Furthermore, to be able to carry a secondment as invited/visiting researcher in the USA New Jersey Center for Biomaterials, she was awarded a full financial grant by FLAD. In the scope of her PhD, Dr. Cristiana published 7 manuscripts in specialized peer-reviewed journals as first author, 1 manuscript as co-author, 1 book chapter and is the author of 2 filled patents. Over the last 7 years as a researcher or a PhD candidate, Cristiana helped in the writing and actively participated in 6 different FCT or CE funded projects. She is now specialized in Biomaterials, Biomaterials characterization, nerve regeneration, growth factors, Tissue engineering and nerve guidance conduits. Overall, her good and impactful scientific work led to more than 20 participations in national and international conferences. Furthermore, she was also an invited speaker at the European Arthroscopy fellowship 2019/SPAT-ESSKA in 2019 at 3Bs research group.
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Identification

Personal identification

Full name
Cristiana de Carvalho

Citation names

  • Carvalho, Cristiana
  • Carvalho, C. R.

Author identifiers

Ciência ID
031E-D08A-0F63
ORCID iD
0000-0001-9215-280X

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Biomaterials

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2015/02/01 - 2019/10/11
Concluded
 Tissue Engineering, Regenerative Medicine and Stem cells (Doutoramento)
Major in Peripheral Nerve Regeneration
Universidade do Minho, Portugal
"Combinatorial Approaches for the Development of Conduits for Guided Peripheral Nerve Regeneration" (THESIS/DISSERTATION)
 Muito Bom
2007/09/15 - 2012
Concluded
 Integrated Master in Pharmaceutical Sciences (Mestrado integrado)
Universidade do Porto Faculdade de Farmácia, Portugal
"Síndrome do Cólon Irritável - Um problema de sáude pública" (THESIS/DISSERTATION)
 15
Affiliation

Science

Category
Host institution 		Employer
2020/01/06 - Current Postdoc (Research) Universidade do Minho, Portugal
3Bs Research Group, Universidade do Minho, Portugal
2015/01 - 2019/11 Researcher (Research) 3Bs Research Group, Universidade do Minho, Portugal
3Bs Research Group, Universidade do Minho, Portugal
2018/01 - 2018/09 Visiting Researcher (Research) New Jersey Center for Biomaterials, United States
New Jersey Center for Biomaterials, United States
2014/05 - 2014/11 Visiting Researcher (Research) Medizinische Hochschule Hannover, Germany
Medizinische Hochschule Hannover, Germany
2010/09/01 - 2010/10/30 Research Trainee (Research) 3Bs Research Group, Universidade do Minho, Portugal
3Bs Research Group, Universidade do Minho, Portugal
Projects

Grant

Designation Funders
2019/01/01 - 2021/12/29 NanOptoNerv - Nano-accelerated nerve regeneration and optogenetic empowering of neuromuscular functionality
PTDC/NAN-MAT/29936/2017
Researcher
3Bs Research Group, Universidade do Minho, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
Ongoing
2016/09/01 - 2019/11/11 UMINHO/BD/7/2016 - PhD scholarship Norte2020
UMINHO/BD/7/2016
PhD Student Fellow
3Bs Research Group, Universidade do Minho, Portugal
 Norte2020
Concluded
2018/02/01 - 2018/09/29 FLAD scholarship (Proj. 29/2018)
Proj 29/2018
Researcher
Fundação Luso-Americana para o Desenvolvimento, Portugal
2018/03 - 2018/09 FROnTHERA - Frontiers of technology for theranostics of cancer, metabolic and neurodegenerative diseases
NORTE-01-0145-FEDER-000023
Researcher
3Bs Research Group, Universidade do Minho, Portugal
Ongoing
2017/03 - 2018/05 ComplexiTE - An integrated multidisciplinary tissue engineering approach combining novel high-throughput screening and advanced methodologies to create complex biomaterials-stem cells constructs
321266
Researcher
3Bs Research Group, Universidade do Minho, Portugal
 Comissão Europeia
Concluded
2014 - 2015 POLARIS - Unlocking the research potential of 3Bs Group, University of Minho, in Nanomedicine field to strengthen its competitive position at the European level
316331
Researcher
3Bs Research Group, Universidade do Minho, Portugal
 Comissão Europeia
Concluded

Contract

Designation Funders
2020/01 - Current 2IQBIONEURO
0624_2IQBIONEURO_6_E
Post-doc Fellow
CiQUS - Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares, Spain
 Interreg
2020/01 - Current 2IQBIONEURO
0624_2IQBIONEURO_6_E
 Interreg
2016/03 - 2017/06 IF/01285/2015 - Advancing Precision Medicine through the Development of In Vitro Tissue Engineered 3D Tumour Models and Multi-omics
IF/01285/2015
Researcher
3Bs Research Group, Universidade do Minho, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
Ongoing
Outputs

Publications

Book chapter
  1. Carvalho, Cristiana; Reis, Rui L.; Oliveira, Joaquim Miguel. "Fundamentals and current strategies for peripheral nerve regeneration and repair". In Advances in Experimental Medicine and Biology (AEMB), edited by Heung Jae Chun; Antonella Motta; Rui L. Reis; Gilson Khang. Singapore: Springer Nature Singapore, 2020.
    Accepted
Conference poster
  1. Carvalho, Cristiana; Oliveira, Joaquim Miguel; Reis, Rui. "Current tendencies for peripheral nerve repair and regeneration: What comes after the hollow nerve guidance conduit?". Paper presented in 1st Discoveries Forum on Regenerative and Precision Medicine, 2019.
  2. Carvalho, C. R.; Oliveira, Joaquim Miguel; Reis, Rui L.. "Neurotrophic Factor Delivery by an Engineered Silk-based Nerve Conduit for Peripheral Nerve Repair". Paper presented in 1st Discoveries Forum on Regenerative and Precision Medicine, 2019.
  3. Carvalho, C. R.; Escobar, Ane; Reis, Rui; Oliveira, Joaquim Miguel. "Nanoparticles for growth factor delivery in nerve guidance conduits: An Overview". Paper presented in TermStem, 2019.
  4. Carvalho, C. R.; Escobar, Ane; Reis, Rui; Oliveira, Joaquim Miguel. "Promotion of peripheral nerve regeneration with optogenetic neuromuscular stimulation". Paper presented in ForeCast, 2019.
  5. Carvalho, Cristiana; Oliveira, Joaquim Miguel; Reis, Rui. "Development and application of new keratin/chitosan biomaterials for Peripheral Nerve Regeneration". Paper presented in Chem2Nature, 2018.
    10.1115/sbc2010-19680
  6. Carvalho, Cristiana; Oliveira, Joaquim Miguel; Reis, Rui. "In vitro and In vivo Evaluation of Different Gellan Gum Formulations for Peripheral Nerve Regeneration". Paper presented in SFB, Society for Biomaterials, 2017.
  7. Carvalho, Cristiana; Oliveira, Joaquim Miguel; Reis, Rui. "Gellan Gum as a new biomaterial for peripheral nerve regeneration". Paper presented in Forecast, 2017.
  8. Carvalho, Cristiana; Reis, Rui; Silva-Correia, Joana; Oliveira, Joaquim Miguel. "Gellan Gum for Peripheral Nerve Regeneration applications: In vitro and in vivo evaluation". Paper presented in Chem2Nature, 2017.
    10.1109/ner.2013.6695919
  9. Carvalho, C. R.; Reis, Rui; Oliveira, Joaquim Miguel. "Application of new keratin/chitosan biomaterials for Peripheral Nerve Regeneration". Paper presented in FBPS, 2017.
  10. Carvalho, Cristiana; Reis, Rui; Oliveira, Joaquim Miguel. "Chitosan films with varying degrees of acetylation for application in peripheral nerve regeneration". Paper presented in WBC, World Biomaterials Congress, 2016.
  11. Carvalho, C. R.; Oliveira, Joaquim Miguel; Reis, Rui. "Chitosan films with varying degrees of acetylation for application in peripheral nerve regeneration". Paper presented in TermStem, 2016.
  12. Carvalho, Cristiana; Oliveira, Joaquim Miguel; Reis, Rui. "Chitosan nanofibers for peripheral nerve applications". Paper presented in ESB, European Society for Biomaterials, 2015.
  13. Carvalho, C. R.; Oliveira, Joaquim Miguel; Reis, Rui. "Chitosan Films with Low Degrees of Acetylation for Peripheral Nerve Regeneration". Paper presented in FBPS, 2015.
  14. Carvalho, Cristiana; Oliveira, Joaquim Miguel; Reis, Rui. "Keratin/chitosan as novel grafts for peripheral nerve regeneration". Paper presented in TermStem, 2014.
    10.1002/term.1932
  15. Carvalho, C. R.; Reis, Rui; Oliveira, Joaquim Miguel. "Keratin/chitosan as novel grafts for peripheral nerve regeneration". Paper presented in TERMIS EU, 2014.
  16. Carvalho, Cristiana; Oliveira, Joaquim Miguel; Reis, Rui. "Chitosan nanofibers as scaffolds for peripheral nerve regeneration". Paper presented in TermStem, 2013.
    10.1002/term.1822
Journal article
  1. Carvalho, Cristiana; Oliveira, Joaquim Miguel; Reis, Rui L.. "Modern Trends for Peripheral Nerve Repair and Regeneration: Beyond the Hollow Nerve Guidance Conduit". Frontiers in Bioengineering and Biotechnology 7 (2019): http://dx.doi.org/10.3389/fbioe.2019.00337.
    Published • 10.3389/fbioe.2019.00337
  2. Carvalho, Mariana R.; Carvalho, Cristiana; Maia, F. Raquel; Caballero, David; Kundu, Subhas C.; Reis, Rui L.; Oliveira, Joaquim Miguel. "Peptide-Modified Dendrimer Nanoparticles for Targeted Therapy of Colorectal Cancer". Advanced Therapeutics 2 11 (2019): 1900132. http://dx.doi.org/10.1002/adtp.201900132.
  3. Carvalho, Cristiana; Silva-Correia, Joana; Oliveira, Joaquim Miguel; Reis, Rui L.. "Nanotechnology in peripheral nerve repair and reconstruction". Advanced Drug Delivery Reviews 148 (2019): 308-343. http://dx.doi.org/10.1016/j.addr.2019.01.006.
    Published • 10.1016/j.addr.2019.01.006
  4. Carvalho, Cristiana; Costa, J. B.; Costa, Lígia; Silva-Correia, Joana; Moay, Zi Kuang; Ng, Kee Woei; Reis, Rui L.; Oliveira, Joaquim Miguel. "Enhanced performance of chitosan/keratin membranes with potential application in peripheral nerve repair". Biomaterials Science 7 12 (2019): 5451-5466. http://dx.doi.org/10.1039/c9bm01098j.
    Published • 10.1039/c9bm01098j
  5. Carvalho, Cristiana; Costa, J. B.; da Silva Morais, Alain; López-Cebral, Rita; Silva-Correia, Joana; Reis, Rui L.; Oliveira, Joaquim Miguel. "Tunable Enzymatically Cross-Linked Silk Fibroin Tubular Conduits for Guided Tissue Regeneration". Advanced Healthcare Materials 7 17 (2018): 1800186. http://dx.doi.org/10.1002/adhm.201800186.
    10.1002/adhm.201800186
  6. Carvalho, Cristiana; Wrobel, S.; Meyer, C.; Brandenberger, C.; Cengiz, I. F.; López-Cebral, R.; Silva-Correia, Joana; et al. "Gellan Gum-based luminal fillers for peripheral nerve regeneration: an in vivo study in the rat sciatic nerve repair model". Biomaterials Science 6 5 (2018): 1059-1075. http://dx.doi.org/10.1039/c7bm01101f.
    10.1039/c7bm01101f
  7. Carvalho, Cristiana; López-Cebral, Rita; Silva-Correia, Joana; Silva, Joana M.; Mano, João F.; Silva, Tiago H.; Freier, Thomas; Reis, Rui; Oliveira, Joaquim Miguel. "Investigation of cell adhesion in chitosan membranes for peripheral nerve regeneration". Materials Science and Engineering: C 71 (2017): 1122-1134. http://dx.doi.org/10.1016/j.msec.2016.11.100.
    Published • 10.1016/j.msec.2016.11.100
Thesis / Dissertation
  1. Carvalho, C. R.. "Combinatorial approaches for the development of conduits for guided peripheral nerve regeneration". PhD, 3Bs Research Group, Universidade do Minho, 2019.

Intellectual property

Patent
  1. Carvalho, Cristiana; Costa, J. B.; Silva-Correia, Joana; Reis, Rui L.; Oliveira, Joaquim Miguel. 2018. "Nerve guidance conduits derived from silk fibroin hydrogels: methods of production and uses thereof". Portugal.
    Granted/Issued
Provisional application for patent
  1. 2019. "Implantable silk hydrogel microfluidic platform, methods of production and uses thereof".
    Protected
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2020/04/04 Biomaterials for the Development of Conduits for Guided Peripheral Nerve Regeneration XI Symposium on Bioengineering
NEB-FEUP/ICBAS (Porto, Portugal)
2019 Delivery of Neurotrophic factors in a Silk-based Nerve Conduit for Peripheral Nerve Repair Society for Biomaterials Annual Meeting
(Seattle, United States)
2019 Neurotrophic Factor Loaded in Enzymatically-Crosslinked Silk Fibroin Conduits for Peripheral Nerve Regeneration TERMIS European Meeting
(Rodes, Greece)
2019 Biomaterials for the Development of Conduits for Guided Peripheral Nerve Regeneration European arthroscopy fellowship 2019 SPAT/ESKKA
3Bs research Group (Guimarães, Portugal)
2015 Chitosan Films with Low Degrees of Acetylation for Peripheral Nerve Regeneration 11th Frontiers in Biomedical Polymers Symposium
(Italy)
2014 Chitosan nanofibers for guided peripheral nerve regeneration 2nd International Symposium on Peripheral Nerve Regeneration
(Italy)

Mentoring / Tutoring

Topic Student name
2019/09 - 2019/10 Silk Fibroin conduits production Ane Escobar
2016/03 - 2016/09 Chitosan nanofibers fabrication Rita López-Cebral
2014/09 - 2015/02 Production and characterization of chitosan/keratin blends José Pedro Gonçalves
Distinctions

Award

2020 Julia Polak European Doctorate Award
European Society of Biomaterials, France

Other distinction

2018 Awarded FLAD Scholarship (Proj. 29/2018)
Fundação Luso-Americana para o Desenvolvimento, Portugal