Gecioni Loch Neckel (0711-6554-4C5E)

Curriculum Vitae

Gecioni Loch Neckel

Graduated in Pharmacy and Biochemistry from the Federal University of Santa Catarina (UFSC - Brazil), Master in Pharmacy in the area of ¿¿Pharmaceutical Technology from UFSC and PhD in Pharmacology also from UFSC. Post-doctorate in Pharmacy at UFSC, with a project to evaluate the biopharmaceutical properties of nanostructured systems containing active substances of natural origin. In research, works in the area of ¿¿Research and Development of Medicines for the Treatment of Cancer and Central Nervous System Diseases.

Identification

Personal identification

Full name: Gecioni Loch Neckel

Citation names

Loch-Neckel, Gecioni

Author identifiers

Ciência ID: 0711-6554-4C5E
ORCID iD: 0000-0002-1435-9394

Knowledge fields

Medical and Health Sciences - Medical Biotechnology - Biomaterials

Education

	Degree	Classification
2006/11 - 2011/03 Concluded	Programa de Pós-Graduação em Farmacologia (Doctor) Universidade Federal de Santa Catarina Centro de Ciências Biológicas, Brazil " Atividade antineoplásica in vitro e in vivo da Chalcona N9 e seu possível mecanismo de ação" (THESIS/DISSERTATION)
2002 - 2004 Concluded	Mestrado em Farmácia (Master) Major in Nanotenologia Farmacêutica Universidade Federal de Santa Catarina (UFSC) Departamento de Ciências Farmacêuticas , Brazil "Avaliação do potencial de utilização de nanocápsulas poliméricas na melhoria da resposta antitumoral de um alcalóide citotóxico, a camptotecina" (THESIS/DISSERTATION)
1990 - 1994 Concluded	Famácia - Análises Clínicas (Graduado) Universidade Federal de Santa Catarina, Brazil

Affiliation

Science

	Category Host institution	Employer
2019/03/20 - Current	Contracted Researcher (Research)	Universidade de Lisboa Faculdade de Farmácia, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2012/03/01 - 2017/07/31	Assistant Professor (University Teacher)	Universidade Federal de Santa Catarina, Brazil
	Universidade Federal de Santa Catarina (UFSC) Departamento de Ciências Farmacêuticas , Brazil

Projects

Contract

	Designation	Funders
2019/03/20 - Current	Development of an autologous exosome-based therapy by engineering microRNAs in microglia and motor-neurons using mice and human models of amyotrophic lateral sclerosis (ALS) PTDC/MED-NEU/31395/2017 Post-doc Universidade de Lisboa Faculdade de Farmácia, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2011/03/15 - 2016/11/30	Development of nanostructured systems containing active substances of natural origin and evaluation of biopharmaceutical properties 230 - Farmácia Post-doc Fellow Universidade Federal de Santa Catarina (UFSC) - Programa de Pos-graduação de Farmácia, Brazil	Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Concluded
2008/03/01 - 2013/11/30	Preparation and characterization of nanoparticles decorated with chitosan for buccal release of curcumin CAPES/COFECUB Colaboradora Universidade Federal de Santa Catarina (UFSC) - Programa de Pos-graduação de Farmácia, Brazil Centre de Recherches sur les Macromolécules Végétales, France	Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Concluded
2003 - 2004	Evaluation of the potential of using nanoparticles to improve the antitumor response of a cytotoxic alkaloid, camptothecin. Conselho Nacional de Desenvolvimento Científico e Tecnológico Conselho Nacional de Desenvolvimento Científico e Tecnológico Master Student Fellow Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil	Conselho Nacional de Desenvolvimento Científico e Tecnológico Concluded

Outputs

Publications

Journal article

Loch-Neckel, Gecioni; Schütz, Francine Elisabeth; Derner, Roberto Bianchini; Lemos-Senna, Elenara. "Obtaining dried extracts from the biomass of the microalga Haematococcus pluvialis by spray drying". Matéria (Rio de Janeiro) 23 4 (2018): e-12221. http://dx.doi.org/10.1590/s1517-707620180004.0555.
Open access • Published • 10.1590/s1517-707620180004.0555
Hädrich, Gabriela; Vaz, Gustavo Richter; Maidana, Michelle; Kratz, Jadel Muller; Loch-Neckel, Gecioni; Favarin, Daniely Cornélio; Rogerio, Alexandre de Paula; et al. "Anti-inflammatory Effect and Toxicology Analysis of Oral Delivery Quercetin Nanosized Emulsion in Rats". Pharmaceutical Research 33 4 (2015): 983-993. http://dx.doi.org/10.1007/s11095-015-1844-6.
10.1007/s11095-015-1844-6
Mazzarino, L.; Loch-Neckel, G.; Bubniak, L.S.; Ourique, F.; Otsuka, I.; Halila, S.; Pedrosa, R.C.; et al. "Nanoparticles made from xyloglucan-block-polycaprolactone copolymers: Safety assessment for drug delivery". Toxicological Sciences 147 1 (2015): 104-115. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940639332&partnerID=MN8TOARS.
10.1093/toxsci/kfv114
Loch-Neckel, G.; Santos-Bubniak, L.; Mazzarino, L.; Jacques, A.V.; Moccelin, B.; Santos-Silva, M.C.; Lemos-Senna, E.. "Orally Administered Chitosan-Coated Polycaprolactone Nanoparticles Containing Curcumin Attenuate Metastatic Melanoma in the Lungs". Journal of Pharmaceutical Sciences 104 10 (2015): 3524-3534. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941181282&partnerID=MN8TOARS.
10.1002/jps.24548
Bicca, M.A.; Costa, R.; Loch-Neckel, G.; Figueiredo, C.P.; Medeiros, R.; Calixto, J.B.. "B2 receptor blockage prevents Aß-induced cognitive impairment by neuroinflammation inhibition". Behavioural Brain Research 278 (2015): 482-491. http://www.scopus.com/inward/record.url?eid=2-s2.0-84911164999&partnerID=MN8TOARS.
10.1016/j.bbr.2014.10.040
Mazzarino, L.; Loch-Neckel, G.; Dos Santos Bubniak, L.; Mazzucco, S.; Santos-Silva, M.C.; Borsali, R.; Lemos-Senna, E.. "Curcumin-loaded chitosan-coated nanoparticles as a new approach for the local treatment of oral cavity cancer". Journal of Nanoscience and Nanotechnology 15 1 (2015): 781-791. http://www.scopus.com/inward/record.url?eid=2-s2.0-84920589255&partnerID=MN8TOARS.
10.1166/jnn.2015.9189
Loch-Neckel, G.; Bicca, M.A.; Leal, P.C.; Mascarello, A.; Siqueira, J.M.; Calixto, J.B.. "In vitro and in vivo anti-glioma activity of a chalcone-quinoxaline hybrid". European Journal of Medicinal Chemistry 90 (2015): 93-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-84910107980&partnerID=MN8TOARS.
10.1016/j.ejmech.2014.11.014
Loch-Neckel, G.. "La barrera hematoencefálica y la concentración de fármacos en el sistema nervioso central a barreira hematoencefá lica e a concentrado de fármacos no sistema nervoso central". Salud(i)Ciencia 19 7 (2013): 646-649. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881561096&partnerID=MN8TOARS.
Open access • Published
Mitozo, P.A.; De Souza, L.F.; Loch-Neckel, G.; Flesch, S.; Maris, A.F.; Figueiredo, C.P.; Dos Santos, A.R.S.; Farina, M.; Dafre, A.L.. "A study of the relative importance of the peroxiredoxin-, catalase-, and glutathione-dependent systems in neural peroxide metabolism". Free Radical Biology and Medicine 51 1 (2011): 69-77. http://www.scopus.com/inward/record.url?eid=2-s2.0-79957941516&partnerID=MN8TOARS.
10.1016/j.freeradbiomed.2011.03.017
Loch-Neckel, G.; Koepp, J.. "The blood-brain barrier and drug delivery in the central nervous system". Revista de Neurologia 51 3 (2010): 165-174. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955624885&partnerID=MN8TOARS.
Published
Loch-Neckel, G.; Crepaldi, M.A.. "Pharmacist contributions for basic care from the perspective of professionals of familial health care teams". Brazilian Journal of Pharmaceutical Sciences 45 2 (2009): 263-272. http://www.scopus.com/inward/record.url?eid=2-s2.0-76149119799&partnerID=MN8TOARS.
10.1590/S1984-82502009000200011
Loch-Neckel, G.; Seemann, G.; Eidt, H.B.; Rabuske, M.M.; Crepaldi, M.A.. "Challenges to an interdisciplinary action in basic care: Implications related to composition of family health teams,Desafios para a ação interdisciplinar na atenção básica: Implicações relativas à composição das equipes de saúde da família". Ciencia e Saude Coletiva 14 SUPPL. 1 (2009): 1463-1472. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349808447&partnerID=MN8TOARS.
Loch-Neckel, G.; Nemen, D.; Puhl, A.C.; Fernandes, D.; Stimamiglio, M.A.; Silva, M.A.; Hangai, M.; Silva, M.C.S.; Lemos-Senna, E.. "Stealth and non-stealth nanocapsules containing camptothecin: In-vitro and in-vivo activity on B16-F10 melanoma". Journal of Pharmacy and Pharmacology 59 10 (2007): 1359-1364. http://www.scopus.com/inward/record.url?eid=2-s2.0-35349015328&partnerID=MN8TOARS.
10.1211/jpp.59.10.0005