???global.info.a_carregar???
Sónia Rocha is a Postdoc Researcher at Dantas Lab at i3S (Instituto de Investigação e Inovação em Saúde). She recently completed her PhD in Pharmaceutical Sciences in the field of Medicinal and Pharmaceutical Chemistry at the Faculty of Pharmacy of the University of Porto in 2024, as part of the PhD Programme in Medicines and Pharmaceutical Innovation. Prior to this, she obtained her Master's degree in Quality Control, specializing in Medicines and Medicinal Plants, also from the Faculty of Pharmacy of the University of Porto, where she graduated in 2018. She earned her Bachelor's degree in Biology from the University of Aveiro in 2016. In terms of scientific contributions, her research has resulted in 12 articles published in indexed international journals. Additionally, she has authored 1 book chapter and 1 commentary. Her h-index is 8 (Google Scholar) and she has 440+ citations. She is the author or co-author of 10 oral presentations and 17 posters presented at national and international conferences.
Read full resume ↓
Identification

Personal identification

Full name
Sónia Aguiar da Rocha

Citation names

  • Rocha, Sónia

Author identifiers

Ciência ID
0810-42B5-1CAB
ORCID iD
0000-0001-7786-2731

Addresses

  • Institute for Research and Innovation in Health (i3S), Rua Alfredo Allen, 208, 4200-135, Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Biochemistry
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Natural sciences - Biological Sciences - Microbiology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2019/03 - 2024/06
Concluded
 Pharmaceutical Sciences (Doutoramento)
Major in Pharmaceutical and Medicinal Chemistry
Universidade do Porto Faculdade de Farmácia, Portugal
"Targeting hepatic glucose metabolism and insulin resistance for diabetes management: exploring the modulating potential of flavonoids, styrylchromones, and pyrazoles" (THESIS/DISSERTATION)
 Unanimously approved
2023/03/01 - 2023/03/30
Concluded
 Erasmus Exchange Program (Outros)
Universidad del País Vasco Facultad de Farmacia, Spain
2016/09 - 2018/11
Concluded
 Quality Control (Mestrado)
Major in Medicines and Medicinal Plants
Universidade do Porto Faculdade de Farmácia, Portugal
"Inhibitory Activity of Chalcones on Key Digestive Enzymes for the Management of Diabetes Mellitus" (THESIS/DISSERTATION)
 18/20
2015/09 - 2016/06
Concluded
 Curricular Internship (Licenciatura)
Universidade de Aveiro, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
"Evaluation of nanoparticle formulations containing rifampicin on in vitro infection of bone marrow-derived mouse macrophages with Mycobacterium avium" (THESIS/DISSERTATION)
 18/20
2012/08 - 2016/06
Concluded
 Biology (Licenciatura)
Major in Biology
Universidade de Aveiro, Portugal
"Effect of photodynamic therapy on the virulence factors of Staphylococcus aureus" (THESIS/DISSERTATION)
 16/20
Affiliation

Science

Category
Host institution 		Employer
2024/09/01 - Current Postdoc (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Dantas Lab at i3S (Instituto de Investigação e Inovação em Saúde), Portugal
2023/08/01 - 2023/12/31 Researcher (Research) REQUIMTE LAQV Porto, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2019/03/01 - 2023/07/31 Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
Projects

Contract

Designation Funders
2020/01/01 - 2024/08/31 Instituto de Investigação do Medicamento - Research Institute for Medicines
UIDB/04138/2020
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
 Fundação para a Ciência e a Tecnologia
2020/01/01 - 2024/08/31 Laboratory for Green Chemistry - Clean Technologies and Processes
UIDB/50006/2020
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Fundação para a Ciência e a Tecnologia
2020/01/01 - 2024/08/31 Instituto de Investigação do Medicamento - Research Institute for Medicines
UIDP/04138/2020
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
 Fundação para a Ciência e a Tecnologia
2020/01/01 - 2024/08/31 Associated Laboratory for Green Chemistry - Clean Technologies and Processes
UIDP/50006/2020
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Fundação para a Ciência e a Tecnologia
2018/06 - 2022/02 NewDMFlav - Interdisciplinary in silico, organic synthesis, in vitro, and in vivo studies towards new antidiabetic flavonoid scaffolds
PTDC/MED-QUI/29241/2017
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Sónia Rocha; Maria Luísa Corvo; Eduarda Fernandes; Marisa Freitas. "Novel Strategies for Managing Diabetes Mellitus Using Lipid-Based Delivery Systems as Vehicles of Polyphenols". In Advances in Health and Disease. Volume 67. 2023.
    Published
Conference poster
  1. Sónia Rocha; Corvo ML; Freitas M; Fernandes E. "Enhancing quercetin efficacy by incorporation in liposomes for modulating hepatic insulin resistance and inflammation in type 2 diabetes". Paper presented in 58th International Conference on Medicinal Chemistry – 58th RICT, 2024.
  2. Sónia Rocha; Proença C; Silva AMS; Corvo ML; Fernandes E; Freitas M. "Targeting hepatic glucose and glycogen metabolism with chromone derivatives". Paper presented in IDF Congress 2022, 2022.
  3. Proença C; Sónia Rocha; Freitas M; Fernandes PA; Artur AMS; Fernandes E. "The effect of flavonoids and pyrazoles in the emerging targets of type 2 diabetes mellitus, PTP1B and FBPase". Paper presented in IDF Congress 2022, 2022.
  4. Sónia Rocha; Ribeiro D; Silva VLM; Silva AMS; Corvo ML; Fernandes M; Freitas M. "New insights on the inhibition of cyclooxygenases by 4-styrylpyrazoles: an enzymatic and human whole blood study". Paper presented in 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting, 2022.
  5. Sónia Rocha; Aniceto N; Guedes RC; Albuquerque HMT; Silva VLM; Silva AMS; Corvo ML; Fernandes E; Freitas M. "Styrylpyrazoles and chromone derivatives as possible glycogen phosphorylase inhibitors: a combined enzyme kinetic and molecular docking study". Paper presented in 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting, 2022.
  6. Sónia Rocha; Catarina Correia; Vera Silva; Artur Silva; M. Luísa Corvo; Eduarda Fernandes; Marisa Freitas. "Polyphenols as potential modulators of type 2 diabetes mellitus through the inhibition of glycogen phosphorylase". Paper presented in 14th World Congress on Polyphenols Applications, 2021.
  7. Sónia Rocha; Mariana Lucas; Vera Silva; Artur Silva; M. Luísa Corvo; Eduarda Fernandes; Marisa Freitas. "The effect of pyrazoles on the emerging diabetic therapeutic targets: protein tyrosine phosphatase 1b and glycogen phosphorylase". Paper presented in 56th International Conference on Medicinal Chemistry (RICT 2021), 2021.
  8. Sónia Rocha; Mariana Lucas; Vera Silva; Artur Silva; Alberto Araújo; Natália Aniceto; Rita Guedes; et al. "Antidiabetic Potential of Pyrazoles: Exploring the Structure-Activity Relationship against Protein Tyrosine Phosphatase 1b and Glycogen Phosphorylase". Paper presented in iMed.Ulisboa Meeting 2021, 2021.
  9. Sónia Rocha; Mariana Lucas; Vera Silva; Artur Silva; Alberto Araújo; Natália Aniceto; Rita Guedes; et al. "Insight into the protein tyrosine phosphatase 1B (PTP1B) inhibitory activity of pyrazoles". Paper presented in 6th International Electronic Conference on Medicinal Chemistry, 2020.
  10. Sónia Rocha; Maria Luísa Corvo; Eduarda Fernandes; Marisa Freitas. "Optimization of kinetic parameters to assess glycogen phosphorylase activity using a microanalysis method". Paper presented in 13th National Organic Chemictry Meeting – 6th National Medicinal Chemistry Meeting, 2020.
  11. Marisa Freitas; Sónia Rocha; Carina Proença; Daniela Ribeiro; Alberto N. Araújo; Artur M. S. Silva; Eduarda Fernandes. "Flavonoids versus chalcones: which are the most efficient inhibitors of key digestive enzymes in the management of diabetes mellitus?". Paper presented in 13th National Organic Chemictry Meeting – 6th National Medicinal Chemistry Meeting, 2020.
  12. Pedro Nicola; Marisa Freitas; Sónia Rocha; Félix Carvalho; Eduarda Fernandes; Daniela Ribeiro. "Optimization of a synaptosomal model to study the effect of carotenoids in peroxynitrite-induced lipid peroxidation". Paper presented in 13th YES Meeting, 2018.
  13. Sónia Rocha; Eduarda Fernandes; Marisa Freitas. "Screening of the anti-diabetic potential of chalcones through the inhibition of a-glucosidase and a-amylase". Paper presented in Italian, Spanish, Portuguese Joint Meeting in Medicinal Chemistry, 2018.
  14. Pedro Nicola; Marisa Freitas; Sónia Rocha; Félix Carvalho; Eduarda Fernandes; Daniela Ribeiro. "Synaptosomes as lipid models to study the inhibition of peroxynitrite-induced lipid peroxidation". Paper presented in Italian, Spanish, Portuguese Joint Meeting in Medicinal Chemistry, 2018.
  15. Sónia Rocha; Eduarda Fernandes; Marisa Freitas. "Inhibitory activity of chalcones on key digestive enzymes for the management of Diabetes mellitus". Paper presented in 11ª Edição do Encontro de Investigação Jovem da Universidade do Porto, 2018.
  16. Joana Magalhães; Alexandre C. C. Vieira; Sónia Rocha; Marcos S. Cardoso; Susana G. Santos; Margarida Borges; Marina Pinheiro; Salette Reis. "Rifampicin-loaded lipid nanoparticles to improve tuberculosis treatment: an active targeting approach". Paper presented in NanoBioMedConf, 2017.
  17. Bartolomeu, Maria; Sónia Rocha; Cunha, Â; Neves, MGPMS; Faustino, MAF; Almeida, A. "Photodynamic inactivation of Staphylococcus aureus: effects on virulence factors". Paper presented in 6th Portuguese Congress of Microbiology and Biotechnology 2015 - MicroBiotec'15, 2015.
Journal article
  1. Sónia Rocha; Beatriz Vicente; Carina Proença; Vera L. M. Silva; Artur M. S. Silva; M. Luísa Corvo; Eduarda Fernandes; Marisa Freitas. "Herbacetin Inhibits Human Fructose 1,6-Bisphosphatase Among a Panel of Chromone Derivatives and Pyrazoles, Demonstrating Positive Effects on Insulin-Resistant HepG2 Cells". Chemical Biology & Drug Design (2024): https://doi.org/10.1111/cbdd.70017.
    10.1111/cbdd.70017
  2. Sónia Rocha; Luísa Corvo, M.; Freitas, Marisa; Fernandes, Eduarda. "Liposomal quercetin: A promising strategy to combat hepatic insulin resistance and inflammation in type 2 diabetes mellitus". International Journal of Pharmaceutics 661 (2024): 124441. http://dx.doi.org/10.1016/j.ijpharm.2024.124441.
    10.1016/j.ijpharm.2024.124441
  3. Sónia Rocha; Silva, Jorge; Silva, Vera L.M.; Silva, Artur M.S.; Corvo, M. Luísa; Freitas, Marisa; Fernandes, Eduarda. "Pyrazoles have a multifaceted anti-inflammatory effect targeting prostaglandin E2, cyclooxygenases and leukocytes’ oxidative burst". The International Journal of Biochemistry & Cell Biology 172 (2024): 106599. http://dx.doi.org/10.1016/j.biocel.2024.106599.
    10.1016/j.biocel.2024.106599
  4. Sónia Rocha; Andreia Amaro; Marcos D. Ferreira-Junior; Carina Proença; Artur M. S. Silva; Vera M. Costa; Sara Oliveira ; et al. "Melanoxetin: A Hydroxylated Flavonoid Attenuates Oxidative Stress and Modulates Insulin Resistance and Glycation Pathways in an Animal Model of Type 2 Diabetes Mellitus". Pharmaceutics 16 2 (2024): 261. https://www.mdpi.com/1999-4923/16/2/261.
    10.3390/pharmaceutics16020261
  5. Sónia Rocha; Natália Aniceto; Rita C. Guedes; Hélio M. T. Albuquerque; Vera L. M. Silva; Artur M. S. Silva; Maria Luísa Corvo; Eduarda Fernandes; Marisa Freitas. "An In Silico and an In Vitro Inhibition Analysis of Glycogen Phosphorylase by Flavonoids, Styrylchromones, and Pyrazoles". Nutrients (2022): https://doi.org/10.3390/nu14020306.
    10.3390/nu14020306
  6. Sónia Rocha; Mariana Lucas; Alberto N. Araújo; M. Luísa Corvo; Eduarda Fernandes; Marisa Freitas. "Optimization and Validation of an In Vitro Standardized Glycogen Phosphorylase Activity Assay". Molecules 26 15 (2021): 4635-4635. https://doi.org/10.3390/molecules26154635.
    10.3390/molecules26154635
  7. Sónia Rocha; Mariana Lucas; Daniela Ribeiro; M. Luísa Corvo; Eduarda Fernandes; Marisa Freitas. "Nano-based drug delivery systems used as vehicles to enhance polyphenols therapeutic effect for diabetes mellitus treatment". Pharmacological Research 169 (2021): 105604-105604. https://doi.org/10.1016/j.phrs.2021.105604.
    10.1016/j.phrs.2021.105604
  8. Sónia Rocha; Lucas, M.; Silva, V.L.M.; Gomes, P.M.O.; Silva, A.M.S.; Araújo, A.N.; Aniceto, N.; et al. "Pyrazoles as novel protein tyrosine phosphatase 1B (PTP1B) inhibitors: An in vitro and in silico study". International Journal of Biological Macromolecules 181 (2021): 1171-1182. https://doi.org/10.1016/j.ijbiomac.2021.04.061.
    10.1016/j.ijbiomac.2021.04.061
  9. Sónia Rocha; Adelaide Sousa; Daniela Ribeiro; Catarina M. Correia; Vera L. M. Silva; Clementina M. M. Santos; Artur M. S. Silva; et al. "A study towards drug discovery for the management of type 2 diabetes mellitus through inhibition of the carbohydrate-hydrolyzing enzymes a-amylase and a-glucosidase by chalcone derivatives.". Food & function 10 (2019): 5510-5520. https://doi.org/10.1039/c9fo01298b.
    10.1039/c9fo01298b
  10. Sónia Rocha; Daniela Ribeiro; Eduarda Fernandes; Marisa Freitas. "Systematic review on anti-diabetic properties of chalcones.". Current Medicinal Chemistry (2018): https://doi.org/10.2174/0929867325666181001112226.
    10.2174/0929867325666181001112226
  11. Alexandre C.C. Vieira; Joana Magalhães; Sónia Rocha; Marcos S. Cardoso; Susana G. Santos; Margarida Borges; Marina Pinheiro; Salette Reis. "Targeted macrophages delivery of rifampicin-loaded lipid nanoparticles to improve tuberculosis treatment". Nanomedicine 12 24 (2017): 2721-2736. https://doi.org/10.2217/nnm-2017-0248.
    10.2217/nnm-2017-0248
  12. Maria Bartolomeu; Sónia Rocha; Ângela Cunha; M. G. P. M. S. Neves; Maria A. F. Faustino; Adelaide Almeida. "Effect of photodynamic therapy on the virulence factors of Staphylococcus aureus". Frontiers in Microbiology 7 (2016): https://doi.org/10.3389/fmicb.2016.00267.
    10.3389/fmicb.2016.00267
Online resource
  1. Sónia Rocha; M. Luísa Corvo; Eduarda Fernandes; Marisa Freitas. The Emerging Target Protein Tyrosine Phosphatase 1B (PTP1B) for Type 2 Diabetes Mellitus Management. 2021. https://www.scientificarchives.com/admin/assets/articles/pdf/the-emerging-target-protein-tyrosine-phosphatase-1b-ptp1b-for-type-2-diabetes-mellitus-management-20211119011116.pdf.
    10.33696/diabetes.3.048
Thesis / Dissertation
  1. "Targeting hepatic glucose metabolism and insulin resistance for diabetes management: exploring the modulating potential of flavonoids, styrylchromones, and pyrazoles.". PhD, 2024. https://sigarra.up.pt/fcup/en/pub_geral.pub_view?pi_pub_base_id=680735.
  2. Sónia Aguiar da Rocha. "Inhibitory Activity of Chalcones on Key Digestive Enzymes for the Management of Diabetes Mellitus". Master, 2018. https://hdl.handle.net/10216/117719.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/11/12 A Novel Approach to Address Hepatic Insulin Resistance and Inflammation with Quercetin Liposomes On-line Workshop "The ABC Day - Usefulness of dietary bioactive compounds and probiotics in promoting health"
University of the Basque Country (Spain) and University of Porto (Portugal)
2023/11/09 Targeting hepatic glucose and glycogen metabolism by flavonoids On-line Workshop ''Usefulness of dietary bioactive compounds and probiotics in promoting health''
University of the Basque Country (Spain) and University of Porto (Portugal)
2023/11 Exploring the Modulatory Effects of Flavonoids and Pyrazoles in Hepatic Insulin Resistance and Glucose Metabolism in Non-Cellular and Cellular Models XXVII Encontro Luso Galego de Química
Sociedade Portuguesa de Química e o Colegio Oficial de Químicos de Galicia (Portugal)
2023/11 Revealing the immunomodulatory potential of pyrazoles and exploring structure activity relationships XXVII Luso-Galician Chemistry Meeting
Sociedade Portuguesa de Química e o Colegio Oficial de Químicos de Galicia (Portugal)
2023/06 Exploring the potential of pyrazoles and flavonoids on emerging pharmacological liver targets for the treatment of diabetes 6th Symposium in Medicinal Chemistry
University of Minho
2023/06 Dual-acting anti-inflammatory activity of pyrazoles through the inhibition of COX-2 and human leukocytes’ oxidative burst 6th Symposium in Medicinal Chemistry
University of Minho (Portugal)
2023/06 Pyrazoles as potential modulators of inflammation through the inhibition of COX-2 activity and human leukocytes’ oxidative burst 16th Meeting of Young Researchers of University of Porto
University of Porto (Portugal)
2021/11 Optimization of In Vitro Experimental Conditions for Glycogen Phosphorylase Inhibition Assay and Demonstration of High Inhibitory Effectiveness by Chromone Derivatives II Bio.Natural -Bioactive Natural Products Research Meeting (Bio.Natural-2021)
Lusófona University
2018/11 Chalcones as a-amylase and a-glucosidase inhibitors for the management of diabetes mellitus XXIV Encontro Luso-Galego de Química
Sociedade Portuguesa de Química (Porto, Portugal)
2018/11 Development and application of a synaptosomal model for the study of peroxynitrite-induced lipid peroxidation XXIV Encontro Luso-Galego de Química
Sociedade Portuguesa de Química (Porto, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/07/10 - 2023/07/14 “Universidade Júnior” program of Porto University in the project: "O admirável mundo da inflamação" (2023/07/10 - 2023/07/14) Universidade do Porto, Portugal
2022/07/25 - 2022/07/29 “Universidade Júnior” program of Porto University in the project: "O admirável mundo da inflamação" (2022/07/25 - 2022/07/29) Universidade do Porto, Portugal
2019/07/08 - 2019/07/12 “Universidade Júnior” program of Porto University in the project: "O admirável mundo da inflamação" (2019/06/08 - 2019/06/12) Universidade do Porto, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2022/12/13 - 2022/12/16 Advanced course (3 ECTS) “Citometria de Fluxo: dos princípios básicos às aplicações práticas”
Universidade do Porto Faculdade de Farmácia, Portugal
2021/07/05 - 2021/07/09 Advanced course (6 ECTS) “Advanced Topics in Medicinal Chemistry and Chemical Biology”
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/03/24 - 2021/03/28 Advanced course “Principles of Drug Design, Synthesis and Structure-Activity Relationships in Medicinal Chemistry”
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/09/14 - 2020/09/18 Advanced course (6 ECTS) “Molecular Biomarkers and Technologies”
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/03/28 - 2020/04/18 Advanced course (6 ECTS) “Non Clinical Efficacy and Safety”
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/10/31 - 2019/10/31 Course “Introdução ao EndNote X9: da criação de uma biblioteca à escrita de um documento”
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/10/24 - 2019/10/24 Course “Web of Science: pesquisa em bases de dados de citações”
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/10/17 - 2019/10/17 Course “PubMed: pesquisa por palavra e assunto, limitação de resultados, obtenção do texto integral dos documentos”
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/03/27 - 2019/03/31 Advanced course (6 ECTS) “Advanced Drug Delivery”
Universidade de Lisboa Faculdade de Farmácia, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023/03/19 - 2023/03/19 Oral presentation and practical activities conducted with children at the Ciência Viva Science Centre (Biological Park of Gaia, Porto, Portugal) under the theme: “Detetive por um dia” (1 hour) (Menos de 4 anos de escolaridade) Ciência Viva, Portugal
2023/02/17 - 2023/02/17 Oral presentation and practical activities conducted with children at the Ciência Viva Science Centre (Biological Park of Gaia, Porto, Portugal) under the theme: “Plantas no Mundo Farmacêutico” (1 hour) (Menos de 4 anos de escolaridade) Ciência Viva, Portugal
2022/05/21 - 2022/05/21 Teaching Assistance in the Curricular Unit: Instrumental Analysis Methods Applied to Pharmacology and Toxicology in the Doctoral Program in Experimental and Clinical Pharmacology and Toxicology (4 hours) (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2022/03/13 - 2022/03/13 Oral presentation and practical activities conducted with children at the Ciência Viva Science Centre (Biological Park of Gaia, Porto, Portugal) under the theme: “Brincar com a Química” (1 hour) (Menos de 4 anos de escolaridade) Ciência Viva, Portugal
2021/11/19 - 2021/11/19 Teaching Assistance in the Curricular Unit: Instrumental Analysis Methods from the Master's degree in Quality Control at the Faculty of Pharmacy of the University of Porto, with the theme “Atomic Spectroscopy” (6 hours) (Mestrado) Universidade do Porto Faculdade de Farmácia, Portugal
2021/04/17 - 2021/04/17 Teaching Assistance in the Curricular Unit: Laboratory Class on Toxicological Control from the Master's degree in Quality Control, with the theme: "Isolation and Detection of Oxidative Burst in Human Neutrophils" (4 hours) (Mestrado) Universidade do Porto Faculdade de Farmácia, Portugal

Mentoring / Tutoring

Topic Student name
2022/09 - 2023/10 A student of the Master’s in Pharmacy at the School of Health of the Polytechnic Institute of Porto, with the theme "Pyrazoles modulate the inflammatory process through the inhibition of COX-2 activity and leukocytes’ oxidative burst". Jorge Miguel Almeida Silva
2022/02 - 2022/08 A student of the Integrated Master in Pharmaceutical Sciences at the Faculty of Pharmacy of the University of Porto, as part of the Research Nucleus of the Student Association, with the theme "Evaluation of a-Glucosidase Enzyme Inhibition by Flavonoids". Beatriz Ferreira Vicente
2021/09 - 2022/02 A student of the Integrated Master in Pharmaceutical Sciences at the Faculty of Pharmacy of the University of Porto, for the curricular unit: Project I, with the theme "Inhibitory Activity of a-Glucosidase Enzyme by Styrylchromones and Styrylpyrazoles" Joana Maria Carvalho Correia

Scientific expedition

Activity description Institution / Organization
2022/03/16 - 2022/03/20 Practical preparation of liposomes containing flavonoids at the Faculty of Pharmacy of the University of Lisbon Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/01/24 - 2022/01/28 Participation in an in vivo study with the theme "Interdisciplinary in silico, organic synthesis, in vitro, and in vivo studies towards new antidiabetic flavonoid scaffolds" at the Faculty of Pharmacy of the University of Coimbra Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/12/13 - 2021/12/17 Participation in an in vivo study with the theme "Use of flavonoids in the prophylaxis of intestinal pro-inflammatory effects of silver nanoparticles" at the Faculty of Pharmacy of the University of Coimbra Universidade de Coimbra Faculdade de Farmácia, Portugal
Distinctions

Award

2019 4-Year Doctoral Fellowship by the FCT PhD Programme in Medicines and Pharmaceutical Innovation (i3DU) (Reference: PD/BD/145169/2019)