Filipe Manuel Coreta Gomes (0A17-FBA2-3276)

Curriculum Vitae

Filipe Manuel Coreta Gomes

Filipe Coreta-Gomes got is PhD in Biological Chemistry in 2014 at Coimbra University. In 2015/2016 he got an MBA at Porto Business School, at Porto University and in 2017 he got a FCT Postdoc Fellowship to work at Chemistry Department, University of Aveiro. From 2019, he got a position of Junior Researcher in this institution, belonging to LAQV&REQUIMTE research unit working in the field of food chemistry, biophysics and biochemistry. During this period Filipe was able to obtain funding from FCT with the project FightSterol (PTDC/QUI-OUT/29373/2017, 212 kEuros) as Principal Investigator, and also was a collaborator (MTS/BRB/0056/2020, 100 kEuros), to explore bioactive properties of several food and its by-products. His research was awarded with young scientist award in 2018 at CocoTea Asia conference held in Hefei (China) and the best poster award in 2019 at EPNOE held in Aveiro (Portugal). He has regularly published is work in peer review journals (23 articles) and have been present in several conferences both with oral (15) and poster (34) communications. He was also involved in a patent (EP22186572.8) submission. He is a invited editor of a special issue of Marine Drugs Journal. Moreover, he has been involved in the supervision of several degrees’ students (15) and master (2). Currently, he is supervising of 3 PhD and i Msc fellows. Its current research interests encompass a) extraction and characterization of compounds (polysaccharides, lipids, phenolic compounds, proteins) from food matrices (coffee, algae, mushrooms and pine nut); b) evaluate the chemical changes suffered during gastrointestinal digestion and fermentation of characterized extracts and evaluating their influence on hypocholesterolemic and neuroprotective potential, c) determine the bioaccessibility and bioavailability of bioactive compounds; d) development of food functional ingredients; e) exploitation of technological applications based on polysaccharides derived fractions as drug delivery, emulsifiers and sequestration agents..

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Identification

Personal identification

Full name: Filipe Manuel Coreta Gomes

Author identifiers

Ciência ID: 0A17-FBA2-3276
ORCID iD: 0000-0001-9498-2460

Education

	Degree	Classification
2017 Concluded	MBA - Master Business Administration (Outros) Universidade do Porto, Portugal	17
2014 Concluded	PhD Chemistry (Doutoramento) Major in Biological Chemistry Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Quantification of Cholesterol Solubilization by Bile Salt Micelles: Implications in its Intestinal Absorption by Passive Processes" (THESIS/DISSERTATION)	n/a
2007 Concluded	Quality Chemistry Control (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Controle e estudo, cinético e termodinâmico, da associação de derivados fosfolipídicos fluorescentes com uma bicamada lipídica na fase líquida desordenada" (THESIS/DISSERTATION)	Muito Bom
2005 Concluded	Chemistry - scientific branch (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Estudo de um biossensor electroquímico para o lactato" (THESIS/DISSERTATION)	14

Affiliation

Science

	Category Host institution	Employer
2019/07/01 - Current	Contracted Researcher (Research)	Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2018 - 2024	Lecturer (University Teacher)	Universidade de Aveiro, Portugal
	Universidade de Aveiro Departamento de Química, Portugal
2018/10/01 - 2019/02/16	Invited Adjunct Teacher (Polytechnic Teacher)	Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal

Others

	Category Host institution	Employer
2017/01/01 - 2019/06/30	Postdoc Fellow on food and functional food chemistry	Universidade de Aveiro Departamento de Química, Portugal

2015/09/01 - 2016/12/31	Executive MBA, Cohitech and other entrepreneurial programs attendance.	Universidade do Porto Porto Business School, Portugal

2014/01/01 - 2016/12/31	Researcher/collaborator - R&D on the area of physical chemistry of membranes, cholesterol homeostasis (passive mechanisms of intestinal absorption) and micellar systems	Universidade de Coimbra Centro de Química de Coimbra, Portugal

2008/08/01 - 2014/01/14	PhD Fellow "Quantification of Cholesterol Solubilization by Bile Salt Micelles: Implications in its Intestinal Absorption by Passive Processes".	Universidade de Coimbra Centro de Química de Coimbra, Portugal

2013/05/01 - 2013/07/31	EMBO Short Term Fellowship "Behavior of bile salts and drugs as membrane modulators: relevance for passive cholesterol absorption"	European Molecular Biology Organization, Portugal

2011 - 2013	Scientific internship	Universidade de Coimbra Centro de Química de Coimbra, Portugal

2010/06/01 - 2010/08/31	EMBO Short Term Fellowship "Are lipids with one saturated and one cis-unsaturated acyl chain chaophilic/chaophobic amphiphiles in the membrane plane?"	European Molecular Biology Organization, Portugal

2008/01/01 - 2008/06/30	Stipendiary of the FCT-financed project "Quantitative modeling of Passive Transcytotic Diffusion of Amphiphilic Molecules Across the Blood-Brain Barrier"	Universidade de Coimbra Centro de Química de Coimbra, Portugal

2006/09/01 - 2007/09/01	Monitor of Chemistry Labs Ia e IIb (chemistry and biology students)	Universidade de Coimbra Centro de Química de Coimbra, Portugal

2005/09/01 - 2006/09/01	Monitor to the chair of Laboratory Practices of Analytical Chemistry (pharmacy students)	Universidade de Coimbra Centro de Química de Coimbra, Portugal

Projects

Grant

	Designation	Funders
2018/07/26 - 2021/07/25	FightSterol: food that reduces cholesterol PTDC/QUI-OUT/29373/2017 Principal investigator Universidade de Aveiro Departamento de Química, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2017/01 - 2020/12	FightSterol: optimized ingredients that reduces cholesterol SFRH/BPD/115561/2016 Post-doc Fellow	Ministério da Ciência Tecnologia e Ensino Superior
2013/01/01 - 2015/12/31	UC-NMR: the voyage from chemical space to biological function RECI / QEQ-QFI / 0168/2012 Integration into Research Grant Fellow	Fundação para a Ciência e a Tecnologia
2008/08 - 2014/01	Quantitative Modelling of the Mechanism of Passive Cholesterol Absorption SFRH/BD/40778/2007 PhD Student Fellow	Fundação para a Ciência e a Tecnologia
2012/01/01 - 2013/12/31	Bioavailability of amphiphilic ligands - drugs and metabolites E-07/12 Integration into Research Grant Fellow Universidade de Coimbra Centro de Química de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2012/01 - 2013/12	Bioavailability of amphiphilic ligands - drugs and metabolites E-07/12	Fundação para a Ciência e a Tecnologia
2013/04/18 - 2013/07/18	Behavior of bile salts and drugs as membrane modulators: relevance for passive cholesterol absorption ASTF 147-2013 Invited Scientist Fellow Universidad de Zaragoza Instituto de Biocomputación y Física de Sistemas Complejos, Spain	European Molecular Biology Organization Concluded
2007/01/01 - 2011/12/31	Two-dimensional micelles and emulsions in lipid bilayers resulting from caophilic / caophobic amphiphilicity of some phospholipids. Biological consequences PTDC / QUI / 68242/2006 Integration into Research Grant Fellow Universidade de Coimbra Centro de Química de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2007/01/01 - 2010/12/31	Quantitative Modeling of Passive Trancytotic Diffusion of Amphiphilic Molecules Across the Blood-Brain Barrier PTTC / SAU-FCF / 69072/2006 Research Fellow Universidade de Coimbra Centro de Química de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/05/01 - 2010/07/31	Are lipids with one saturated and one cis-unsaturated acyl chain chaophilic / chaophobic amphiphiles in the membrane plane? ASTF 3-2010 Invited Scientist Fellow Lunds Universitet Kemicentrum, Sweden	European Molecular Biology Organization Concluded

Other

	Designation	Funders
2013/01/01 - 2015/12/31	Financing of the Strategic Plan for R&D Units - 2013/2015 - OE 007630 UID / QUI / 00313/2013 Other

Outputs

Publications

Book chapter	Machado, Fernanda; Coimbra, Manuel; Coreta-Gomes, Filipe Manuel. Corresponding author: Coreta-Gomes, Filipe Manuel. "Coffee dietary fiber: features and hypocholesterolemic effects". In Coffee in Health and Disease Prevention 2e (Book), 277-285. Academi Press, 2025. Published
Conference abstract	Coreta-Gomes, Filipe Manuel; Guido R. Lopes; Cláudia P. Passos; Carlos F. G. C. Geraldes; Maria João Moreno; Laura Nyström; Manuel A. Coimbra. "In vitro hypocholesterolemic effect of coffee compounds". Paper presented in CocoTea2019, Bremen, 2019. Published
Conference paper	Filipe Manuel Coreta-Gomes. "Decoding Coffee Cardiometabolic Potential: Structure-Health Function Relationships". 2024. 10.3390/ICC2024-18023 Fernanda Machado; Irene Gómez-Domínguez; Raul Hurtado-Ribeira; Diana Martin; Manuel A. Coimbra; María Dolores del Castillo; Filipe Coreta-Gomes. "Colonic Fermentation of Coffee Melanoidins and Resulting Cardioprotective Metabolites". 2023. 10.3390/ICC2023-14836
Conference poster	Coreta-Gomes, Filipe; Vanesa Sánchez-Martín; Machado, Fernanda; Manuel Coimra; Maria Dolores del Castillo. Corresponding author: Maria Dolores del Castillo. "Effect of in vitro human colonic fermented coffee melanoidins on colon cancer cell proliferation". Paper presented in 5th International Electronic Conference on Foods, 2024. Laronha, Helena; Coreta-Gomes, Filipe Manuel; Coimbra, Manuel; Coelho, Elisabete. Corresponding author: Coelho, Elisabete. "Assessment of cholesterol-lowering effects of mushrooms". Paper presented in XXII NATIONAL CONGRESS OF BIOCHEMISTRY, 2024. Laronha, Helena; Coreta-Gomes, Filipe Manuel; Coimbra, Manuel; Coelho, Elisabete. "Mushroom polysaccharides: Key players in cholesterol-lowering effect". Paper presented in XVII Encontro de Química Alimentar,, 2024. Arranca, Maria Inês; Coreta-Gomes, Filipe Manuel; Coimbra, Manuel; Coelho, Elisabete. Corresponding author: Coelho, Elisabete. "Development of functional ingredients based on mushroom ß-Glucans". Paper presented in XVII Encontro de Química Alimentar, 2024. Laronha, Helena; Coreta-Gomes, Filipe Manuel; Coimbra, Manuel; Coelho, Elisabete. Corresponding author: Coelho, Elisabete. "Hypocholesterolemic Potential of Mushroom Polysaccharides: Key Structure-Function Relationships". Paper presented in 4th International Conference on Natural Products and Human Health, 2024. Laronha, Helena; Coreta-Gomes, Filipe Manuel; Coimbra, Manuel; Coelho, Elisabete. Corresponding author: Coelho, Elisabete. "Evaluation of bile acid binding capacity of Lactarius deliciosus wild mushrooms polysaccharides and its extracts”,". Paper presented in Biophysics Festival, 2024. Machado, Fernanda; Irene Gómez-Domínguez; Raul Hurtado-Ribeira; Diana Martin; Coimbra, Manuel; Maria Dolores del Castillo; Coreta-Gomes, Filipe Manuel. Corresponding author: Coreta-Gomes, Filipe Manuel. "In vitro digestion of coffee brew and their fractions: their relevance towards cardioprotective potential". Paper presented in 8th International Conference on Food Digestion (ICFD2024), 2024. Laronha, Helena; Arranca, Maria Inês; Bárbara Oliveira; Coreta-Gomes, Filipe Manuel; Coimbra, Manuel A.; Coelho, Elisabete. "Mushroom as potential hypocholesterolemic functional ingredients". Paper presented in Dare2Change, Innovation-Driven Agrifood Business, 2023. Machado, Fernanda; Irene Gómez; Alba Tamargo; Carolina Cuevo; Raquel Diego; Maria Del Castillo; Manuel A. Coimbra; Coreta-Gomes, Filipe Manuel. "Coffee soluble fibers: study of cholesterol-lowering properties and colonic fermentability". Paper presented in Dare2Change, Innovation-Driven Agrifood Business, 2023. Laronha, Helena; Bárbara Oliveira; Manuel A. Coimbra; Coreta-Gomes, Filipe Manuel; Coelho, Elisabete. "Wild endogenous mushroom species: ethanolic and aqueous extracts for biological studies". Paper presented in XVI Encontro de Química dos Alimentos, 2022. Maria Inês Bonifácio; Machado, Fernanda; Ramiro Almeida; Coimbra, Manuel A.; Coreta-Gomes, Filipe Manuel. "Antioxidant activity of free and adsorbed coffee low molecular weight compounds in polysaccharides and melanoidins". Paper presented in EPNOE, 2022. Maria Inês Bonifácio; Fernanda Machado; Ramiro Almeida; Maria João Moreno; Manuel A. Coimbra; Coreta-Gomes, Filipe Manuel. "Study of biophysical properties of coffee ingredients". Paper presented in BIOPHYSICS FESTIVAL ¿ 2 nd Meeting of Young Biophysicists, 2022. Maria Inês Bonifácio; Fernanda Machado; Ramiro Almeida; Coimbra, Manuel A.; Coreta-Gomes, Filipe Manuel. "Unveil melanoidins potential towards neuroprotective activity". Paper presented in XIII Biochemistry Day, 2022. Machado, Fernanda; Maria Del Castillo; Manuel A. Coimbra; Coreta-Gomes, Filipe. Corresponding author: Coreta-Gomes, Filipe. "HEART HEALTHY COFFEE: COFFEE COMPONENTS AS FUNCTIONAL HYPOCHOLESTEROLEMIC AGENTS". Paper presented in XXVI Jornadas Internacionales de Nutríco Práctica, 2022. "Coffee: Is it possible to improve its potential to decrease cholesterol?". Paper presented in Dare2Change, Innovation-Driven Agrifood Business, 2021. "Pine nut skin valorization: towards a functional food ingredient". Paper presented in XV EQA Química dos Alimentos, 2021. "Marine polysaccharides structural features and their influence on hypocholesterolemic function". Paper presented in Marine polysaccharides structural features and their influence on hypocholesterolemic function, 2021. "Hypocholesterolemic potential of coffee polysaccharides: dependence on processing parameters". Paper presented in 7th International Iberian Biophysics Congress, 2021. "Influence of processing parameters on coffee polysaccharides hypocholesterolemic potential". Paper presented in Ciência 2021 – Encontro com a Ciência e Tecnologia em Portugal, 2021. Coreta-Gomes, Filipe Manuel. "Effect of food extracted compounds on cholesterol bioaccessibility". Paper presented in EPNOE, 2019. Coreta-Gomes, Filipe Manuel. "Effect of galactomannans from locust bean gum on cholesterol bioaccessability: a measure of its hypocholesterolemic potential". Paper presented in Glupor, 2019. Coreta-Gomes, Filipe Manuel; Guido R. Lopes; Cláudia Passos; Maria João Moreno; Laura Nyström; Manuel A. Coimbra. "Hypocholesterolemic properties of chemical compounds present in coffee extracts". Paper presented in Glupor Meeting, 2017. Coreta-Gomes, Filipe Manuel. "Emulsification of Cholesterol in Bile Salt Micelles: Relevance for Cholesterol Absorption". Paper presented in Biophysical Society 53rd Annual Meeting, San Francisco, 2014. Coreta-Gomes, Filipe Manuel. "Quantification of cholesterol solubilized in bile salt micellar aqueous solutions using 13C NMR". Paper presented in IV Ibero-American NMR Meeting, 2012. Coreta-Gomes, Filipe; Carlos Frederico Gusmão Geraldes; Vaz, Winchil L.C.; Maria João Moreno. "Quantification of cholesterol solubilized in bile salt micellar aqueous solutions using 13C NMR". Paper presented in IV Ibero-American NMR Meeting, 2012. 10.1109/mwsym.2014.6848570 Coreta-Gomes, Filipe M.; Carlos Frederico Gusmão Geraldes; Vaz, Winchil L.C.; Maria João Moreno. "Emulsification of Cholesterol in Bile Salt Micelles: Relevance for Cholesterol Absorption". Paper presented in Biophysical Society 53rd Annual Meeting, San Francisco, 2010. 10.1109/nebc.2003.1216119 Coreta-Gomes, Filipe Manuel. "Chain Length Effect on the Association of Fluorescent amphiphiles with lipid bilayer membranes". Paper presented in Biophysical Society 52rd Annual Meeting, Boston, 2009.
Journal article	Jianqiao Zou; Zhaoshuo Yu; Fangzhou He; Sihao Luo; Lijing Ke; Huaiyu Gu; Filipe M. Coreta-Gomes; Patrick Wall. "Spatial distribution of antioxidant activity in baguette and its modulation of proinflammatory cytokines in RAW264.7 macrophages". npj Science of Food (2024): https://doi.org/10.1038/s41538-024-00302-w. 10.1038/s41538-024-00302-w Mustafa Fevzi Karagöz; Emine Koçyigit; Tevfik Koçak; Ayçil Özturan Sirin; Mehmet Arif Icer; Duygu Agagündüz; Filipe Coreta-Gomes. "Decoding coffee cardiometabolic potential: Chemical composition, nutritional, and health relationships". Comprehensive Reviews in Food Science and Food Safety (2024): https://doi.org/10.1111/1541-4337.13414. 10.1111/1541-4337.13414 Fernanda Machado; Irene Gómez-Domínguez; Raul Hurtado-Ribeira; Diana Martin; Manuel A. Coimbra; Maria Dolores del Castillo; Filipe Coreta-Gomes. "In vitro human colonic fermentation of coffee arabinogalactan and melanoidin-rich fractions". International Journal of Biological Macromolecules (2024): http://dx.doi.org/10.1016/j.ijbiomac.2024.133740. 10.1016/j.ijbiomac.2024.133740 Silva, Soraia P.; Coreta-Gomes, Filipe; Coimbra, Manuel A.; Coelho, Elisabete. "Pine nut skin as a source of phytosterols and alkanediols - Hypocholesterolemic potential and development of sustainable vegan emulsifiers". LWT 197 (2024): 115934. http://dx.doi.org/10.1016/j.lwt.2024.115934. 10.1016/j.lwt.2024.115934 Filipe Coreta-Gomes; Inês M.V. Silva; Cláudia Nunes; Ildefonso Marin-Montesinos; Dmitry Evtuguin; Carlos F.G.C. Geraldes; Maria João Moreno; Manuel A. Coimbra. "Contribution of non-ionic interactions on bile salt sequestration by chitooligosaccharides: Potential hypocholesterolemic activity". Journal of Colloid and Interface Science 646 (2023): 775-783. Open access • 10.1016/j.jcis.2023.05.056 Fernanda Machado; Manuel A. Coimbra; Maria Dolores del Castillo; Filipe Coreta-Gomes. "Mechanisms of action of coffee bioactive compounds – a key to unveil the coffee paradox". Critical Reviews in Food Science and Nutrition (2023): 1-23. 10.1080/10408398.2023.2221734 Ana S. P. Moreira; Diana Gaspar; Sónia Ferreira; Alexandra I. Correia; Manuel Vilanova; Marie-Mathilde Perrineau; Philip D. Kerrison; et al. "Water-Soluble Saccharina latissima Polysaccharides and Relation of Their Structural Characteristics with In Vitro Immunostimulatory and Hypocholesterolemic Activities". Marine Drugs (2023): https://www.mdpi.com/1660-3397/21/3/183. 10.3390/md21030183 Cristiana L. Pires; Inês M. V. Silva; Manuel A. Coimbra; Maria João Pedrosa Ferreira Moreno Silvestre; Coreta-Gomes, F.. "Effect of Coffee on the Bioavailability of Sterols". Foods (2022): https://www.mdpi.com/2304-8158/11/19/2935. 10.3390/foods11192935 Inês M. V. Silva; Fernanda Machado; Maria João Pedrosa Ferreira Moreno Silvestre; Cláudia Nunes; Manuel A. Coimbra; Coreta-Gomes, F.. "Polysaccharide Structures and Their Hypocholesterolemic Potential". Molecules (2021): https://www.mdpi.com/1420-3049/26/15/4559. 10.3390/molecules26154559 Coreta-Gomes, Filipe Manuel; Lopes, Guido R.; Passos, Cláudia P.; Vaz, Inês M.; Machado, Fernanda; Geraldes, Carlos F. G. C.; Moreno, Maria João; Nyström, Laura; Coimbra, Manuel A.. "In Vitro Hypocholesterolemic Effect of Coffee Compounds". Nutrients 12 2 (2020): 437. http://dx.doi.org/10.3390/nu12020437. 10.3390/nu12020437 Neves, Maria C.; Filipe, Hugo A. L.; Reis, Rita Leones; Prates Ramalho, João P.; Coreta-Gomes, Filipe; Moreno, Maria J.; Loura, Luis M. S.. "Interaction of Bile Salts With Lipid Bilayers: An Atomistic Molecular Dynamics Study". Frontiers in Physiology 10 (2019): http://dx.doi.org/10.3389/fphys.2019.00393. Published • 10.3389/fphys.2019.00393 Coreta-Gomes, Filipe M.; Vaz, Winchil L. C.; Moreno, Maria J.. "Effect of Acyl Chain Length on the Rate of Phospholipid Flip-Flop and Intermembrane Transfer". The Journal of Membrane Biology 10.1007 (2017): 1-12. Published • 10.1007/s00232-017-0009-4 Coreta-Gomes, Filipe M.; Vaz, Winchil L. C.; Wasielewski, Emeric; Geraldes, Carlos F. G.; Moreno, Maria João. "Quantification of Cholesterol Solubilized in Dietary Micelles: Dependence on Human Bile Salt Variability and the Presence of Dietary Food Ingredients". Langmuir 32 18 (2016): 4564-4574. Published • 10.1021/acs.langmuir.6b00723 Coreta-Gomes, Filipe M.; Martins, Patrícia A. T.; Velazquez-Campoy, Adrián; Vaz, Winchil L. C.; Geraldes, Carlos F. G.; Moreno, Maria João. "Interaction of Bile Salts with Model Membranes Mimicking the Gastrointestinal Epithelium: A Study by Isothermal Titration Calorimetry". Langmuir 31 33 (2015): 9097-9104. Published • 10.1021/acs.langmuir.5b01810 Ferreira, Tiago Mendes; Coreta-Gomes, Filipe; Ollila, O. H. Samuli; Moreno, Maria João; Vaz, Winchil L. C.; Topgaard, Daniel. "Cholesterol and POPC segmental order parameters in lipid membranes: solid state 1H–13C NMR and MD simulation studies". Physical Chemistry Chemical Physics 15 6 (2013): 1976-1976. Published • 10.1039/c2cp42738a Filipe, Hugo A. L.; Coreta-Gomes, Filipe M.; Velazquez-Campoy, Adrian; Almeida, Ana R.; Peixoto, Andreia F.; Pereira, Mariette M.; Vaz, Winchil L. C.; Moreno, Maria J.. "Synthesis and Characterization of a Lipidic Alpha Amino Acid: Solubility and Interaction with Serum Albumin and Lipid Bilayers". The Journal of Physical Chemistry B 117 13 (2013): 3439-3448. Published • 10.1021/jp307874v Coreta-Gomes, Filipe M.; Vaz, Winchil L.C.; Wasielewski, Emeric; Geraldes, Carlos F.G.C.; Moreno, Maria João. "Quantification of cholesterol solubilized in bile salt micellar aqueous solutions using 13C nuclear magnetic resonance". Analytical Biochemistry 427 1 (2012): 41-48. Published • 10.1016/j.ab.2012.04.028 Cardoso, Renato M. S.; Martins, Patricia A. T.; Gomes, Filipe; Doktorovova, Slavomira; Vaz, Winchil L. C.; Moreno, Maria Joa~o. "Chain-Length Dependence of Insertion, Desorption, and Translocation of a Homologous Series of 7-Nitrobenz-2-oxa-1,3-diazol-4-yl-Labeled Aliphatic Amines in Membranes". The Journal of Physical Chemistry B 115 33 (2011): 10098-10108. Published • 10.1021/jp203429s Barosa, Cristina; Almeida, Manuela; Caldeira, M. Madalena; Gomes, Filipe; Jones, John G.. "Contribution of proteolytic and metabolic sources to hepatic glutamine by 2H NMR analysis of urinary phenylacetylglutamine 2H-enrichment from 2H2O". Metabolic Engineering 12 1 (2010): 53-61. Published • 10.1016/j.ymben.2009.08.009 Cardoso, R. M. S.; Filipe, H. A. L.; Gomes, F.; Moreira, N. D.; Vaz, W. L. C.; Moreno, M. J.. "Chain Length Effect on the Binding of Amphiphiles to Serum Albumin and to POPC Bilayers". The Journal of Physical Chemistry B 114 49 (2010): 16337-16346. Published • 10.1021/jp105163k MARTINS, P; Gomes, F.; VAZ, W; MORENO, M. "Binding of phospholipids to ß-Lactoglobulin and their transfer to lipid bilayers". Biochimica et Biophysica Acta (BBA) - Biomembranes 1778 5 (2008): 1308-1315. Published • 10.1016/j.bbamem.2008.02.011 Mendes, Ana C.; Caldeira, M. Madalena; Silva, Claudia; Burgess, Shawn C.; Merritt, Matthew E.; Gomes, Filipe; Barosa, Cristina; et al. "Hepatic UDP-glucose13C isotopomers from [U-13C]glucose: A simple analysis by13C NMR of urinary menthol glucuronide". Magnetic Resonance in Medicine 56 5 (2006): 1121-1125. Published • 10.1002/mrm.21057 Jones, John G.; Barosa, Cristina; Gomes, Filipe; Carina Mendes, Ana; Delgado, Teresa C.; Diogo, Luisa; Garcia, Paula; et al. "NMR Derivatives for Quantification of 2 H and 13C Enrichment of Human Glucuronide from Metabolic Tracers". Journal of Carbohydrate Chemistry 25 2-3 (2006): 203-217. Published • 10.1080/07328300600732840

Intellectual property

Patent

Coreta-Gomes, Filipe Manuel; Coelho, Elisabete; Coimbra, Manuel; Ana Soraia Pires Silva. 2024. "GRANULATION ACTIVE FRACTIONS OF PINE NUT SKIN, METHODS AND USES THEREOF". Portugal.
Expired
Coreta-Gomes, Filipe Manuel; Coimbra, Manuel; Coelho, Elisabete; Ana Soraia Pires Silva. 2024. "FRAÇÕES ATIVAS OBTIDAS POR FRACIONAMENTO GRANULOMÉTRICO DA PELE DE PINHÃO, MÉTODOS E SEUS USOS". Portugal.
Pending

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2024/10/17	Decoding Coffee Cardiometabolic Potential: Structure-Health Function Relationships	International Coffee Convention 2024 Coffee in Transition International Coffee Convention (Manheim, Germany)
2024/10/10	Cholesterol lowering foods: a quest towards a functional ingredient	XVII Encontro de Química Alimentar SPQ (Vila Real, Portugal)
2024/09/20	Explore cardioprotective potential of coffee and its extracts	4th International Conference on Natural Products and Human Health, Aveiro University SPQ (Aveiro, Portugal)
2023/10/03	Colonic Fermentation of Coffee Melanoidins and Resulting Cardioprotective Metabolites	International Coffee Convention International Coffee Convention (Manheim, Germany)
2023/09/26	Chitoligosaccharides hypocholesterolemic activity: relevance of ionic and non-ionic interactions	EPNOE EPNOE (Graz, Austria)
2023/07/16	Contribution of non-ionic interactions on bile salt binding by chitooligosaccharides: potential hypocholesterolemic activity	XXVIII Encontro Nacional da Sociedade Portuguesa de Química Portuguese Chemistry Society (Aveiro, Portugal)
2023/06	Polysaccharides hypocholesterolemic potential: from structure to function	XXII Congress, EuroFoodChem XXII (Belgrade)
2023/01/18	Polysaccharides as hypocholesterolemic food ingredients	14th International Meeting of the Portuguese Carbohydrate Group – GLUPOR 14 Caparica Portuguese Chemistry Society (Caparica, Portugal)
2022/10/26	Hypocholesterolemic functional food based in polysaccharides: from structure to function	XVI Encontro de Química dos Alimentos Portuguese Chemistry Society (Castelo Branco, Portugal)
2022/06/03	Polysaccharides hypocholesterolemic potential: from structure to function	BIOPHYSICS FESTIVAL – 2 nd Meeting of Young Biophysicists Portuguese Biophysics Society (Aveiro, Portugal)
2021/09/05	Hypocholesterolemic potential of food ingredients: from structure to function	XV EQA Química dos Alimentos SPQ (Madeira)
2019/06	In vitro hypocholesterolemic effect of coffee compounds	Congress on CocoTea 2019 University of Jacobs (Bremen, Germany)
2018/10	Quantification of Cholesterol Solubilized in Dietary Micelles: Effect of Coffee Extracts	First International Congress on Cocoa Coffee and Tea Asia Anhui Agricultural University China (Hefei, China)
2017/03	Passive permeation of small molecules through biomembranes: mechanism and implications for drug delivery	NIH Seminar NIH Bethseda USA (Bethseda, United States)
2016/06	Interaction of bile salts with model membranes mimicking the gastrointestinal epithelium: a study by isothermal titration calorimetry	5th International Iberian Biophysics Congress Porto University, Chemistry Department (Porto, Portugal)
2016/04	Importance of passive processes in cholesterol homeostasis - absorption at the intestine and distribution in the blood	5th PYChem/1st EYChem (Guimaraes, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2022/05/04 - Current	Structure-function relationships of mushroom polysaccharides, sterols and other relevant compounds on anti-cancer and hypocholesterolemic properties Co-supervisor	Universidade de Aveiro, Portugal
2021/01/01 - Current	In vitro gastrointestinal digestion-fermentation of coffee for validation of its hypocholesterolemic potential as a functional ingredient Supervisor	Bioquímica (PhD) Universidade de Aveiro, Portugal
2021/12 - 2022/12/16	NeuroMelanoidins: unveil melanoidins potential towards neuroprotective activity Supervisor	Biothecnology (Master) Universidade de Aveiro, Portugal
2020/02 - 2020/07	AromaDeCafé: explorar as famílias químicas de compostos voláteis de café desde o grão à bebida Supervisor	Bioquímica (Degree) Universidade de Aveiro Departamento de Química, Portugal
2018 - 2019	Hypocholesterolemic potential effect of locust bean gum fibers Co-supervisor	Bioquímica (Degree) Universidade de Aveiro Departamento de Química, Portugal
2018 - 2019	Evaluate the potential of soluble fibers extracted from apple pomace as hypocholesterolemic food ingredients Supervisor	Dietética e Nutrição (Degree) Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2018/05/30 - 2018/05/30	Mini-symosium The life of Inorganic Chemistry: from molecules to imaging (2018/05/30 - 2018/05/30) Symposium (Member of the Organising Committee)	Universidade de Coimbra Centro de Química de Coimbra, Portugal
2014/09/30 - 2014/10/03	NMR Basics: Theory, Processing and Analysis (2014/09/30 - 2014/10/03) Workshop (Member of the Organising Committee)	Universidade de Coimbra Centro de Química de Coimbra, Portugal
2013/02/26 - 2013/03/01	NMR Basics: Theory, Processing and Analysis (2013/02/26 - 2013/03/01)	Universidade de Coimbra Centro de Química de Coimbra, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2017/11 - Current	Program Nestlé out of the box - entrepreneurship program that selected FightSterol project for first round of mentoring. Other	Program Nestlé out of the box Nestle Portugal S A, Portugal
2019/10/21 - 2019/10/25	Effect of food extracted compounds on cholesterol bioaccessibility Congress	EPNOE Universidade de Aveiro, Portugal
2019/09/03 - 2019/09/05	Effect of galactomannans from locust bean gum on cholesterol bioaccessability: a measure of its hypocholesterolemic potential Congress	Glupor Meeting Universidade do Porto Centro de Investigação em Química, Portugal
2018/01/21 - 2018/01/21	Symposium on Medicine & Health Cultivation and Wellness Symposium	Symposium on Medicine & Health Cultivation and Wellness Guangdong Academy of Agricultural Sciences Institute of Fruit Tree Research, China
2017/09/11 - 2017/09/13	Hypocholesterolemic properties of chemical compounds present in coffee Congress	Glupor Meeting Universidade de Aveiro, Portugal
2012/09/25 - 2012/09/28	Quantification of cholesterol solubilized in bile salt micellar aqueous solutions using 13C NMR Congress	IV Ibero-American NMR Meeting Universidade de Aveiro, Portugal
2010 - 2010	Emulsification of Cholesterol in Bile Salt Micelles: Relevance for Cholesterol Absorption Congress	Biophysical Society 54rd Annual Meeting Archbold Biological Station, United States
2009 - 2009	Chain Length Effect on the Association of Fluorescent Phospholipid Derivatives with Lipid Bilayer Membranes Congress	Biophysical Society 53rd Annual Meeting ABS, Portugal
2009 - 2009	Chain Length Effect on the Association of Fluorescent amphiphiles with lipid bilayer membranes Congress	Biophysical Society 53rd Annual Meeting
2007 - 2007	Interaction of diC10PE-NBDwith Albumin and Lipid Bilayers Congress	II-Iberian Meeting of Colloids and Interfaces SPQ, Portugal
2006 - 2006	[U-d7]glucose disposal into hepatic glycogen in healthy humans Congress	Medicinal Chemistry Meeting in 21 st century SPQ, Portugal
2006 - 2006	Quantification of Glucose Positional 2H Enrichment by 2H NMR Congress	European Association for the Study of Diabetes, 42nd EASD Annual Meeting EASD, Denmark
2005 - 2005	Quantification of Glucose Positional 2H Enrichment by 2H NMR Congress	6th International Meeting of the Portuguese Carbohydrate Group 3rd Iberian Carbohydrate Meeting Glucpor, Portugal

Committee member

	Activity description Role	Institution / Organization
2023/06/03 - 2023/06/03	Biophysics Party, 2nd Meeting of Young Biophysicists” Member	Universidade de Aveiro, Portugal
2018/02/16 - 2018/02/17	Mini-symosium on P-glycoprotein Member	Universidade de Coimbra Centro de Química de Coimbra, Portugal

Conference scientific committee

	Conference name	Conference host
2023/05/30 - 2023/06/01	Biophysics Festival	I3S Porto
2018/07/06 - 2018/07/06	Biophysics Party	ITQB Lisbon, Portuguese Society Biophysics

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2018 - 2019	Iniciation to R&D: Methodologies of work-group and interpersonal interaction	Chemistry (Mestrado)	Universidade de Coimbra Centro de Química de Coimbra, Portugal
2018 - 2019	Bromatology: science of food	Dietética e Nutrição (Licenciatura)	Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal

Interview (newspaper / magazine)

	Activity description	Newspaper / Forum
2024/09/25	Opinion article entilted Chemistry, sustainability and society - Food that reduce cholesterol (Alimentos que reduzem o colesterol)	Diário de Notícias

Distinctions

Award

2024	Honourable Best Oral presentation
2024	Best poster
2024	Best poster
2018	COCOTEA International Meeting Young Scientist Award
2017	Glupor Meeting Poster Award

Other distinction

2013	EMBO Short Term Fellowship European Molecular Biology Organization, Portugal
2010	EMBO Short Term Fellowship European Molecular Biology Organization, Portugal
2010	Calouste Gulbenkian Foundation Travel Award Fundação Calouste Gulbenkian, Portugal
2009	Biophysical Society International Travel Award