???global.info.a_carregar???
Luís Lopes-da-Costa is full professor of the Faculty of Veterinary Medicine of the University of Lisbon (FMV-ULisboa) since 2006, as Chairman of Reproduction and Obstetrics, and Head of the Reproduction & Development Laboratory (R&D Lab) of CIISA (Centre for Interdisciplinary Research in Animal Health), the research centre of FMV-ULisboa. His main research focus on the embryo-maternal interactions leading to pregnancy establishment and maintenance, and on the host-pathogen interactions during the pathogenesis of reproductive diseases. Currently, his research addresses the gametes’ interactions leading to fertilization and early embryo development, and the pathogenesis of postpartum uterine inflammation and infection. Luís Lopes-da-Costa is the Head of LabRepA (Laboratory of Animal Reproduction), a unit of FMV-ULisboa dedicated to counseling and services to community stakeholders. LabRepA entails an officially certified germplasm bank (sperm cells, oocytes, embryos and reproductive tissue cells of several animal species), an official assisted reproductive techniques’ team (ART team), and an officially certified and accredited (by IPAQ, the Portuguese Institute of Quality) diagnostic laboratory of infectious reproductive diseases. During his institutional path, Luís Lopes-da-Costa held several positions, including those of President of the Institutional Animal Welfare Body, President of the Clinics Department, President of the School Council and Coordinator of CIISA. Since 2018, he holds the position of President of the Scientific Council, and since 2021 is was appointed Director of the Associate Laboratory for Animal and Veterinary Science (AL4AnimalS), a research platform joining the three national research centers dedicated to animal and veterinary science. AL4AnimalS develops three thematic lines within the concept of One Health.
Read full resume ↓
Identification

Personal identification

Full name
Luís Lopes-da-Costa

Citation names

  • Lopes-da-Costa, Luís

Author identifiers

Ciência ID
0A1F-AC68-0919
ORCID iD
0000-0001-5165-3034

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
German Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Spanish; Castilian Intermediate (B1) Advanced (C1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2002
Concluded
 Veterinary Medicine (Título de Agregado)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
"No thesis needed" (THESIS/DISSERTATION)
 Aproved (Aprovado)
1995
Concluded
 Doutoramento em Medicina Veterinária (Doutoramento)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
"Studies on the use of native Alentejano and Mertolengo cattle as embryo donors and recipients" (THESIS/DISSERTATION)
 Honor and Distinction (Distinção e Louvor)
1990
Concluded
 Provas de Aptidão Pedagógica e Capacidade Científica (Mestrado)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
"Embryo transfer in cattle" (THESIS/DISSERTATION)
 Very Good (Muito Bom)
1984
Concluded
 Medicina Veterinária (Licenciatura)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
""n/a"" (THESIS/DISSERTATION)
 Aproved (Aprovado)
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2006 - Current Full Professor (University Teacher) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal

Positions / Appointments

Category
Host institution 		Employer
2021 - Current Organic Unit Director Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Laboratório Associado para a Ciência Animal e Veterinária AL4AnimalS, Portugal
2019 - Current President of the Scientific Council Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal

Others

Category
Host institution 		Employer
2003/12/17 - Current Tenure (Nomeação Definitiva) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2014/05/29 - 2018 Coordenator of CIISA - Centre for Interdisciplinary Research in Animal Health Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2006/03/06 - 2018 President of the Ethics and Animal Wellfare Commitee (Presidente da Comissão de Ética e Bem-Estar Animal) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2008/03/26 - 2014/03/06 President of the Department of Clinics (Presidente do Departamento de Clínica) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2011/07/13 - 2013/11/30 President of the School Council (Presidente do Conselho de Escola) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
1999/02/23 - 2006/07/27 Associate Professor (Professor Associado) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
1995/11/15 - 1999/02/22 Assistant Professor (Professor Auxiliar) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
1990/05/12 - 1995/11/14 Assistant (Assistente) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
1986/09/30 - 1990/05/11 Adjunct Assistant (Assistente Estagiário) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Projects

Grant

Designation Funders
2022 - Current Role of Notch and Wnt signaling during pre-implantation development on subsequent fetal growth
EXPL/CVT-CVT/1173/2021
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
Ongoing
2018 - 2021 Innovative biotechnological solutions for the control of bovine genital campylobacteriosis
FCT-02/SAICT/2017(no. 30145)
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2017 - 2021 NAT-OMEGA3
PDR2020-101-031461
Principal investigator
European Agricultural Fund for Rural Development
Ongoing
2017 - 2021 VITINDEMNE
PDR2020-101-031789
Principal investigator
European Agricultural Fund for Rural Development
Ongoing
2020 - 2020 Interaction between bovine preputial-associated Campylobacterspecies and placental tissue
CIISA 11/2019
Supervisor
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Ongoing
2018 - 2018 Development of cell culture models to study campylobacter fetus subsp. venerealis-host cells interactions
CIISA 15/2018
Supervisor
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Concluded
2018 - 2018 Bovine Viral Diarrohea and Bovine Genital Campylobacteriosis in Portugal, a prevalence survey and impact assessement
CIISA 7/2018
Supervisor
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Concluded
2014 - 2014 Notch/Wnt signaling cross-talk in the regulation of pre-implantation of embryo development and early pregnancy establishment
EXPL/CVT/REP/2289/2013
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010 - 2013 The Notch-Delta signaling pathway in the reproductive function of the mouse and cow
PTDC/CVT/105022/2008
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2008 - 2011 Relationships embryo-uterus-ovary determining embryonic and foetal survival in cattle
PTDC/CVT/65690/2006
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2008 - 2011 Contribution to the study of the physiopathology of the complex cystic endometrial hyperplasia - pyometra in the bitch
PTDC/CVT/66587/2006
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2008 - 2011 Relationships embryo-uterus-ovary determining embryonic and foetal survival in cattle
PTDC/CVT/65690/2006
 Fundação para a Ciência e a Tecnologia
2005 - 2008 Role of prostaglandins and endotoxins in the establishment and persistence of puerperal endometritis in the dairy cow
POCTI/CVT/48733/2002
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2004 - 2004 Contribution to the study of cystic endometrial hyperplasia in the bitch
74 Hiperplasia Endométrio
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Concluded
2004 - 2004 Morphologic and cytologic changes in the testis of Lusitano horses throughout the year, evaluated by ultrasound and biopsy
62 Cavalos
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Concluded
2002 - 2004 Embryo-ovary interactions in the establishment of pregnancy in cattle
58 Embrio-Ovárica
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Concluded
2002 - 2004 Characterization of a new gene Delta (mDll4) by conditional transgenesis in the mice
POCTI/CVT/48766/2002
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2002 - 2004 Embryo-ovary interactions in the establishment of pregnancy in cattle
58 Embrio-Ovárica
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
2000 - 2001 Characterization of a new gene Delta (mDelta-4) with endothelial expression in mammals by transgenic techniques
Sapiens POCTI/34204/CVT/2000
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2000 - 2001 Characterization of a new gene Delta (mDelta-4) with endothelial expression in mammals by transgenic techniques
Sapiens POCTI/34204/CVT/2000
 Fundação para a Ciência e a Tecnologia
1999 - 2000 Regulation of muscle development in mammals through a new transcription factor with bHLH domain, and its interaction with Notch signaling
PRAXIS/P/CVT/11187/1998
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
1998 - 2000 Production of transgenic mice by genetic manipulation of embryonic totipotent cells
34 Transgénicos
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Concluded
1998 - 2000 Production of transgenic mice by genetic manipulation of embryonic totipotent cells
34 Transgénicos
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
1997 - 1999 Relationship between toxins and ovarian cysts in postpartum dairy cattle
22 Toxinas
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Concluded
1997 - 1999 Endocrinological study of the etiology and hormonal treatment of ovarian cysts in postpartum cattle
PRAXIS, 3/3.2/CA/1989/95
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
1997 - 1999 Endocrinological study of the etiology and hormonal treatment of ovarian cysts in postpartum cattle
PRAXIS, 3/3.2/CA/1989/95
 Fundação para a Ciência e a Tecnologia
1996 - 1998 Development of a bovine embryo sexing technique by DNA Y-specific probes and PCR
21 Sexagem
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Concluded
1996 - 1998 Development of a bovine embryo sexing technique by DNA Y-specific probes and PCR
21 Sexagem
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
1995 - 1998 Alternative production systems for native cattle breeds
PRAXIS, 3/3.2/AGR/01/94
Researcher
Concluded
1993 - 1996 Development of in vitro bovine and ovine embryo production techniques
PBIC/C/AGR/1477/92
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
1990 - 1993 Embryo transfer in native cattle breeds
PMCT/C/AGR/135/90
Principal investigator
Fundação para a Ciência e a Tecnologia
Concluded
1990 - 1993 Embryo transfer in native cattle breeds
PMCT/C/AGR/135/90
 Fundação para a Ciência e a Tecnologia
1989 - 1991 Superovulation of cattle through the intra-vulvo-submucosae route
89/Nat3/10
Principal investigator
Fundação para a Ciência e a Tecnologia
1989 - 1991 Superovulation of cattle through the intra-vulvo-submucosae route
89/Nat3/10
 Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2021/02/01 - 2023 PTDC/CVT-CVT/6932/2020 - Exploring resolving mechanisms in cow persistent uterine and mammary inflammation
PTDC/CVT-CVT/6932/2020
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Book
  1. Lopes-da-Costa, Luís. Advances in Animal Health, Medicine and Production. Springer International Publishing. 2020.
    Published • 10.1007/978-3-030-61981-7 • Editor
Book chapter
  1. Murta, D.; Silva, E.; Trindade, A.; Henrique, D.; Duarte, A.; Lopes-da-Costa, L.. "Unraveling Notch Signaling in Reproductive Biology". In Advances in Animal Health, Medicine and Production, 389-402. Springer International Publishing, 2020.
    Published • 10.1007/978-3-030-61981-7_21
  2. Silva, E.; Silva, M. F.; Henriques, S.; Diniz, P.; Carneiro, C.; Lopes-da-Costa, L.; Mateus, L.. "The Role of Uteropathogenic Escherichia Coli in the Development of Canine Pyometra". In Advances in Animal Health, Medicine and Production, 510-527. Springer International Publishing, 2020.
    Published • 10.1007/978-3-030-61981-7_28
  3. Pereira, R. M. L. N.; Marques, C. C.; Pimenta, J.; Barbas, J. P.; Baptista, M. C.; Diniz, P.; Torres, A.; Lopes-da-Costa, L.. "Assisted Reproductive Technologies (ART) Directed to Germplasm Preservation". In Advances in Animal Health, Medicine and Production, 199-215. Springer International Publishing, 2020.
    Published • 10.1007/978-3-030-61981-7_10
  4. Pimenta, J.; Lopes-da-Costa, L.; Marques, C. C.; Barbas, J. P.; Baptista, M. C.; Pereira, R. M. L. N.. "From Villains to Heroes: Insights into the Antagonizing Functions of Prion like Genes and Proteins". In Advances in Animal Health, Medicine and Production, 373-388. Springer International Publishing, 2020.
    Published • 10.1007/978-3-030-61981-7_20
  5. Lopes da Costa, L.; Freitas Duarte, A.; Robalo Silva, J.. "Biotechnology of reproduction and Development: From de biomedical model to enterprise innovation". In A portrait of state-of-the-art research at the Technical University of Lisbon, edited by Pereira, M.S., 259-272. Dordrecht, Netherlands: Springer, 2007.
    Published
Conference abstract
  1. Lopes-da-Costa, L.; Robalo Silva, J.. "Beef cow herd reproductive performance in the extensive Mediterranean scenario". Paper presented in Proceedings of the 20th Annual Conference of the European Society for Domestic Animal Reproduction (ESDAR) and the 13th Conference of the Spanish Association for Animal Reproduction (AERA). In Reproduction in Domestic Animals Vol. 51, Suppl. 2, pp 50, 2016.
    Published
  2. Batista, M.; Diniz, P.; Torres, A.; Murta, D.; Mateus, L.; Lopes-da-Costa, L.; Silva, E.. "Notch and Wnt interplay in the regulation of the pace of embryo developmental kinetics". Paper presented in Reproduction in Domestic Animals, Vol. 51, Suppl2. , pp. 59, 2016.
    Published
  3. Murta, D.; Batista, M.; Silva, E.; Trindade, A.; Duarte, A.; Lopes-da-Costa, L.. "Sperm motility is regulated by Notch signaling in the epididymal epithelium". Paper presented in Reproduction in Domestic Animals, Vol. 51, Suppl2, Pg. 60, Lisboa, Portugal, 2016.
    Published
  4. Diniz, P.; Batista, M.; Murta, D.; Torres, A.; Mateus, L.; Lopes-da-Costa, L.; Silva, E.. "Notch expression in bovine spermatozoa". Paper presented in Reproduction in Domestic Animals, Vol. 51, Suppl2, Pp.85, 2016.
  5. Mateus, L.; Henriques, S.; Lopes da Costa, L.; Silva, E.. "Canine pyometra: uterine innate immune response and Escherichia coli determinants of virulence". Paper presented in 19th Annual Conference of the European Society for Domestic Animal Reproduction (ESDAR), 17-19 Setembro 2015, Albena, Bulgária. In Reproduction in Domestic Animals, 50 (Suppl 3), pp 27., 2015.
  6. Batista, M.; Murta, D.; Diniz, P.; Mateus, L.; Lopes-da-Costa, L.; Silva, E.. "Notch signaling in the bovine oviduct and spermatozoa: a regulator of the spermatozoa-oviduct interaction?". Paper presented in Annual Conference of the Society for Reproduction and Fertility, Oxford, United Kingdom., 2015.
  7. Silva, E.; Henriques, S.; Lopes da Costa, L.; Mateus, L.. "Pathogenesis of canine pyometra: Escherichia coli determinants of virulence and uterine innate immune response". Paper presented in Scientific workshop - "Endometritis as a cause of infertility in domestic animals: new diagnostic and therapeutic strategies", 6-8 Outubro 2013, Olsztyn, Poland, pp 35., 2013.
    Published
  8. Mateus, L.; Henriques, S.; Merino C.; Pomba, C.; Lopes da Costa, L.; Silva, E.. "Virulence genotypes of Escherichia coli canine isolates from pyometra, cystitis and fecal origin". Paper presented in Cell Symposia: microbiome and host health, Lisbon, 2013.
  9. Murta, D.; Batista, M.; Silva, E.; Trindade, A.; Henrique, D.; Duarte, A.; Lopes-da-Costa, L.. "Changes in Notch signaling pathway expression in the testis are associated to spermatogenesis along the mouse post-natal life". Paper presented in Proceedings 17th International Congress in Animal Reproduction (ICAR 2012), Vancouver, Canada. In Reproduction in Domestic Animals 47 (Suppl. 4), pp. 601., 2012.
    Published • 10.1158/1557-3125.devbiolca15-a36
  10. Torres, A.; Batista, M.; Diniz, P.; Mateus, L.; Lopes-da-Costa, L.. "Prostaglandin and progesterone production by bovine embryos and co-cultured luteal cells in two in vitro culture systems". Paper presented in Proceedings 17th International Congress in Animal Reproduction (ICAR 2012), Vancouver, Canada. In Reproduction in Domestic Animals 47 (Suppl. 4), pp. 448., 2012.
    Published
  11. Henriques, S.; Silva, E.; Niza, M.M.; Carneiro, C.; Vilela, C.L.; Lopes-da-Costa, L.; Mateus, L.. "Prevalence of virulence factor genes of E. coli is associated to the different outcomes of uterine infection in the bovine and canine species". Paper presented in Proceedings 17th International Congress in Animal Reproduction (ICAR 2012), Vancouver, Canada. In Reproduction in Domestic Animals 47 (Supplement 4), 464., 2012.
    Published
  12. Henriques, S.; Silva, E.; Ferreira-Dias, G.; Lopes-da-Costa, L.; Mateus, L.. "Pro and anti-apoptotic expression of BCL-2 family proteins in canine endometrium during the oestrous cycle, and correlation with proliferation and apoptosis patterns". Paper presented in Proceedings 45th Annual Conference of Physiology and Pathology of Reproduction and 37th Mutual Conference on Veterinary and Human Reproductive Medicine, Berlin, Germany. In Reproduction in Domestic Animals, 47 (Suppl. 2), pp. 27, 2012.
    Published
  13. Silva, E.; Henriques, S.; Brito, S.; Ferreira-Dias, G.; Lopes-da-Costa, L.; Mateus, L.. "Toll like receptors in the canine endometrium". Paper presented in Proceedings 45th Annual Conference of Physiology and Pathology of Reproduction and 37th Mutual Conference on Veterinary and Human Reproductive Medicine, Berlin, Germany. In Reproduction in Domestic Animals, 47 (Suppl. 2), pp. 49., 2012.
    Published • 10.1158/1538-7445.am2013-2332
  14. Barros, L.; Diniz, P.; Mateus, L.; Lopes-da-Costa, L.. "Effects of calving related diseases (CRD) on reproductive parameters of high-yielding dairy cows". Paper presented in Proceedings World Buiatric Congress, Lisboa, Portugal, pp. 201., 2012.
  15. Henriques, S.; Silva, E.; Ferreira-Dias, G.; Lopes-da-Costa, L.; Mateus, L.. "Apoptosis and proliferation in the canine endometrium during estrous cycle". Paper presented in Proceedings 15th Annual Conference of the European Society for Domestic Animal Reproduction (ESDAR), Antalya, Turkey. In Reproduction in Domestic Animals, 46 (Suppl. 3), pp. 112-113., 2011.
    Published
  16. Torres, A.C.; Batista, M.; Diniz, P.; Mateus, L.; Lopes-da-Costa, L.. "Interaction between bovine embryo and co-cultured luteal cells in two in vitro culture systems: effects on embryo development". Paper presented in Proceedings 15th Annual Conference of the European Society for Domestic Animal Reproduction (ESDAR), Antalya, Turkey. In Reproduction in Domestic Animals, 46 (Suppl. 3), pp. 115., 2011.
    Published
  17. Lopes-da-Costa, L.; Chagas e Silva, J.; Deloche, M.C.; Jeanguyot, N.; Humblot, P.; Horta, A.E.M.. "Pregnancy-specific protein bovine (PSPB) concentrations in whole and demi embryo derived early pregnancies". Paper presented in Proceedings 15th Annual Conference of the European Society for Domestic Animal Reproduction (ESDAR), Antalya, Turkey. In Reproduction in Domestic Animals, 46 (Suppl. 3), pp. 123-124., 2011.
    Published
  18. Silva, E.; Brito, S.; Henriques, S.; Ferreira-Dias, G.; Lopes-da-Costa, L.; Mateus, L.. "Transcription of Toll-like receptors and prostaglandin production in the canine endometrium during the oestrous cycle". Paper presented in Proceedings 15th Annual Conference of the European Society for Domestic Animal Reproduction (ESDAR), Antalya, Turkey. In Reproduction in Domestic Animals, 46 (Suppl. 3), pp. 149-150., 2011.
    Published
  19. Torres, A.C.; Batista, M.; Diniz, P.; Mateus, L.; Lopes-da-Costa, L.. "Effects of co-culture with luteal cells and oil overlaying on in vitro bovine embryo development". Paper presented in Proceedings 2nd General Meeting of GEMINI, Sardignia, Italy, pp. 48., 2009.
  20. Batista, M.; Torres, A.C.; Diniz, P.; Mateus, L.; Lopes-da-Costa, L.. "Performance of luteal cells in an in vitro culture system designed for bovine in vitro embryo production". Paper presented in Proceedings 2nd General Meeting of GEMINI, Sardignia, Italy, pp. 81., 2009.
  21. Silva, E.; Gaivão, M.; Leitão, S.; Lopes-da-Costa, L.; Mateus, L.. "Evaluation of COX-2 and PGES gene expression in whole blood during the peripartum of dairy cows.". Paper presented in Proceedings 16th International Congress on Animal Reproduction ICAR 2008, Budapest, Hungary. In Reproduction in Domestic Animals 43 (Suppl. 3), pp. 53., 2008.
    Published • 10.13031/2013.11639
  22. Silva, E.; Gaivão, M.; Leitão, S.; Jost, B.; Carneiro, C.; Vilela, C.; Lopes-da-Costa, L.; Mateus, L.. "Genomic characterization of Arcanobacterium pyogenes isolates recovered throughout the puerperium of dairy cows". Paper presented in Proceedings 16th International Congress on Animal Reproduction ICAR 2008, Budapest, Hungary. In Reproduction in Domestic Animals 43 (Suppl. 3), pp. 65., 2008.
    Published
  23. Chagas e Silva, J.; Lopes-da-Costa, L.. "Accessory corpora lutea induced by hCG treatment enhance survival of half-embryos in high yielding lactating dairy cows.". Paper presented in Proceedings 16th International Congress on Animal Reproduction ICAR 2008, Budapest, Hungary. In Reproduction in Domestic Animals 43 (Suppl. 3), pp. 34-35., 2008.
    Published
  24. Mateus, L.; Lopes-da-Costa, L.; Carvalho, H.. "Peripartum profiles of serum and uterine fluid inflammatory response proteins in dairy cows that spontaneously recovered from puerperal endometritis". Paper presented in Proceedings 7th Annual Conference of the European Society for Domestic Animal Reproduction (ESDAR), Dublin, Ireland. In Reproduction in Domestic Animals 38 (4), pp. 360., 2003.
    Published
Journal article
  1. Diniz, Patrícia; Leites, Inês; R. Batista, Mariana; Torres, Ana Catarina; Mateus, Luísa; Lopes-da-Costa, Luís; Silva, Elisabete. "Characterization of expression patterns and dynamic relocation of Notch proteins during acrosome reaction of bull spermatozoa". Scientific Reports 14 1 (2024): http://dx.doi.org/10.1038/s41598-024-65950-0.
    10.1038/s41598-024-65950-0
  2. Ferreira, Ana Filipa; Machado-Simões, Juliana; Moniz, Inês; Soares, Maria; Carvalho, Alexandra; Diniz, Patrícia; Ramalho-Santos, João; et al. "Chemical reversion of age-related oocyte dysfunction fails to enhance embryo development in a bovine model of postovulatory aging". Journal of Assisted Reproduction and Genetics (2024): http://dx.doi.org/10.1007/s10815-024-03151-4.
    10.1007/s10815-024-03151-4
  3. Silva, Marta Filipa; Pereira, Gonçalo; Mateus, Luísa; da Costa, Luís Lopes; Silva, Elisabete. "Design of a multi-epitope-based vaccine candidate against Bovine Genital Campylobacteriosis using a reverse vaccinology approach". BMC Veterinary Research 20 1 (2024): http://dx.doi.org/10.1186/s12917-024-04006-x.
    10.1186/s12917-024-04006-x
  4. Gonçalo Pereira; Gilles Charpigny; Yongzhi Guo; Elisabete Silva; Marta Filipa Silva; Tao Ye; Luís Lopes-da-Costa; Patrice Humblot. "Characterization of circulating microRNA profiles of postpartum dairy cows with persistent subclinical endometritis". Journal of Dairy Science (2023): https://doi.org/10.3168/jds.2023-23616.
    10.3168/jds.2023-23616
  5. Silva, Marta Filipa; Kienesberger, Sabine; Pereira, Gonçalo; Mateus, Luísa; Lopes-da-Costa, Luís; Silva, Elisabete. "Molecular diagnosis of bovine genital campylobacteriosis using high-resolution melting analysis". Frontiers in Microbiology 13 (2022): http://dx.doi.org/10.3389/fmicb.2022.969825.
    10.3389/fmicb.2022.969825
  6. Capela, Luís; Leites, Inês; Romão, Ricardo; Lopes-da-Costa, Luís; Pereira, Rosa M. Lino Neto. "Impact of Heat Stress on Bovine Sperm Quality and Competence". Animals 12 8 (2022): 975. http://dx.doi.org/10.3390/ani12080975.
    10.3390/ani12080975
  7. Pimenta, Jorge M.B.G.A.; Pires, Virgínia M.R.; Nolasco, Sofia; Castelo-Branco, Pedro; Marques, Carla C.; Apolónio, Joana; Azevedo, Rita; et al. "Post-transcriptional silencing of Bos taurus prion family genes and its impact on granulosa cell steroidogenesis". Biochemical and Biophysical Research Communications 598 (2022): 95-99. http://dx.doi.org/10.1016/j.bbrc.2022.02.012.
    10.1016/j.bbrc.2022.02.012
  8. Pereira, Gonçalo; Guo, Yongzhi; Silva, Elisabete; Bevilacqua, Claudia; Charpigny, Gilles; Lopes-da-Costa, Luís; Humblot, Patrice. "Progesterone differentially affects the transcriptomic profiles of cow endometrial cell types". BMC Genomics 23 1 (2022): http://dx.doi.org/10.1186/s12864-022-08323-z.
    10.1186/s12864-022-08323-z
  9. Pereira, Gonçalo; Simões, Patrícia; Bexiga, Ricardo; Silva, Elisabete; Mateus, Luisa; Fernandes, Tatiane; Alves, Susana P.; Bessa, Rui J.B.; Lopes-da-Costa, Luis. "Effects of feeding rumen-protected linseed fat to postpartum dairy cows on plasma n-3 polyunsaturated fatty acid concentrations and metabolic and reproductive parameters". Journal of Dairy Science 105 1 (2022): 361-374. http://dx.doi.org/10.3168/jds.2021-20674.
    10.3168/jds.2021-20674
  10. Silva, Marta F.; Pereira, Ana L.; Fraqueza, Maria J.; Pereira, Gonçalo; Mateus, Luísa; Lopes-da-Costa, Luís; Silva, Elisabete. "Genomic and Phenotypic Characterization of Campylobacter fetus subsp. venerealis Strains". Microorganisms 9 2 (2021): 340. http://dx.doi.org/10.3390/microorganisms9020340.
    In press • 10.3390/microorganisms9020340
  11. Batista, Mariana R; Diniz, Patrícia; Murta, Daniel; Torres, Ana; Lopes-da-Costa, Luís; Silva, Elisabete. "Balanced Notch-Wnt signaling interplay is required for mouse embryo and fetal development". Reproduction (2021): http://dx.doi.org/10.1530/rep-20-0435.
    In press • 10.1530/rep-20-0435
  12. Silva, Marta Filipa; Duarte, Ana; Pereira, Gonçalo; Mateus, Luísa; Lopes-da-Costa, Luís; Silva, Elisabete. "Assessment of Campylobacter fetus subsp. venerealis molecular diagnosis using clinical samples of bulls". BMC Veterinary Research 16 1 (2020): http://dx.doi.org/10.1186/s12917-020-02634-7.
    Published • 10.1186/s12917-020-02634-7
  13. Pereira, Gonçalo; Bexiga, Ricardo; Chagas e Silva, João; Silva, Elisabete; Ramé, Christelle; Dupont, Joëlle; Guo, Yongzhi; Humblot, Patrice; Lopes-da-Costa, Luís. "Adipokines as biomarkers of postpartum subclinical endometritis in dairy cows". Reproduction 160 3 (2020): 417-430. http://dx.doi.org/10.1530/rep-20-0183.
    Published • 10.1530/rep-20-0183
  14. Silva, Marta Filipa; Pereira, Gonçalo; Carneiro, Carla; Hemphill, Andrew; Mateus, Luísa; Lopes-da-Costa, Luís; Silva, Elisabete. "Campylobacter portucalensis sp. nov., a new species of Campylobacter isolated from the preputial mucosa of bulls". PLOS ONE 15 1 (2020): e0227500. http://dx.doi.org/10.1371/journal.pone.0227500.
    Published • 10.1371/journal.pone.0227500
  15. Batista, M.; Diniz, P.; Torres, A.; Murta, D.; Lopes-da-Costa, L.; Silva, E.. "Notch signaling in mouse blastocyst development and hatching". BMC Developmental Biology. DOI: 10.21203/rs.3.rs-22442/v1 (2020):
    In press
  16. Badenes, Marina; Trindade, Alexandre; Pissarra, Hugo; Lopes-da-Costa, Luís; Duarte, António. "Delta-like 4/Notch signaling promotes Apc Min/+ tumor initiation through angiogenic and non-angiogenic related mechanisms". BMC Cancer 17 1 (2017): http://dx.doi.org/10.1186/s12885-016-3036-0.
    Published • 10.1186/s12885-016-3036-0
  17. Henriques, Sofia; Silva, Elisabete; Silva, Marta F.; Carvalho, Sandra; Diniz, Patrícia; Lopes-da-Costa, Luís; Mateus, Luisa. "Immunomodulation in the canine endometrium by uteropathogenic Escherichia coli". Veterinary Research 47 1 (2016): http://dx.doi.org/10.1186/s13567-016-0396-z.
    Published • 10.1186/s13567-016-0396-z
  18. Murta, D.; Batista, M.; Silva, E.; Trindade, A.; Henrique, D.; Duarte, A.; Lopes-da-Costa, L.. "Notch signaling in the epididymal epithelium regulates sperm motility and is transferred at a distance within epididymosomes". Andrology 4 2 (2016): 314-327. http://dx.doi.org/10.1111/andr.12144.
    Published • 10.1111/andr.12144
  19. Murta, D.; Batista, M.; Trindade, A.; Silva, E.; Mateus, L.; Duarte, A.; Lopes-da-Costa, L.. "Dynamics of Notch signalling in the mouse oviduct and uterus during the oestrous cycle". Reproduction, Fertility and Development 28 11 (2016): 1663. http://dx.doi.org/10.1071/rd15029.
    Published • 10.1071/rd15029
  20. Henriques, S.; Silva, E.; Cruz, S.; Silva, M. F.; Ferreira-Dias, G.; Lopes-da-Costa, L.; Mateus, L.. "Oestrous cycle-dependent expression of Fas and Bcl2 family gene products in normal canine endometrium". Reproduction, Fertility and Development 28 9 (2016): 1307. http://dx.doi.org/10.1071/rd14245.
    Published • 10.1071/rd14245
  21. Murta, D.; Batista, M.; Silva, E.; Trindade, A.; Mateus, L.; Duarte, A.; Lopes-da-Costa, L.. "Differential expression of Notch component and effector genes during ovarian follicle and corpus luteum development during the oestrous cycle". Reproduction, Fertility and Development 27 7 (2015): 1038. http://dx.doi.org/10.1071/rd13399.
    Published • 10.1071/rd13399
  22. Murta, Daniel; Batista, Marta; Trindade, Alexandre; Silva, Elisabete; Henrique, Domingos; Duarte, António; Lopes-da-Costa, Luís. "In Vivo Notch Signaling Blockade Induces Abnormal Spermatogenesis in the Mouse". PLoS ONE 9 11 (2014): e113365. http://dx.doi.org/10.1371/journal.pone.0113365.
    Published • 10.1371/journal.pone.0113365
  23. Torres, A.; Batista, M.; Diniz, P.; Silva, E.; Mateus, L.; Lopes-da-Costa, L.. "Effects of oocyte donor age and embryonic stage of development on transcription of genes coding for enzymes of the prostaglandins and progesterone synthesis pathways in bovine in vitro produced embryos". Zygote 23 6 (2014): 802-812. http://dx.doi.org/10.1017/s0967199414000446.
    Published • 10.1017/s0967199414000446
  24. Henriques, Sofia; Silva, Elisabete; Lemsaddek, Abdelhak; Lopes-da-Costa, Luís; Mateus, Luisa. "Genotypic and phenotypic comparison of Escherichia coli from uterine infections with different outcomes: Clinical metritis in the cow and pyometra in the bitch". Veterinary Microbiology 170 1-2 (2014): 109-116. http://dx.doi.org/10.1016/j.vetmic.2014.01.021.
    Published • 10.1016/j.vetmic.2014.01.021
  25. Torres, Ana Catarina; Boruszewska, Dorota; Batista, Mariana; Kowalczyk-Zieba, Ilona; Diniz, Patricia; Sinderewicz, Emilia; Saulnier-Blache, Jean Sebastian; Woclawek-Potocka, Izabela; Lopes-da-Costa, Luis. "Lysophosphatidic Acid Signaling in Late Cleavage and Blastocyst Stage Bovine Embryos". Mediators of Inflammation 2014 (2014): 1-11. http://dx.doi.org/10.1155/2014/678968.
    Published • 10.1155/2014/678968
  26. Boruszewska, Dorota; Torres, Ana Catarina; Kowalczyk-Zieba, Ilona; Diniz, Patricia; Batista, Mariana; Lopes-da-Costa, Luis; Woclawek-Potocka, Izabela. "The Effect of Lysophosphatidic Acid duringIn VitroMaturation of Bovine Oocytes: Embryonic Development and mRNA Abundances of Genes Involved in Apoptosis and Oocyte Competence". Mediators of Inflammation 2014 (2014): 1-12. http://dx.doi.org/10.1155/2014/670670.
    Published • 10.1155/2014/670670
  27. Mateus, Luisa; Henriques, Sofia; Merino, Carolina; Pomba, Constança; Lopes da Costa, Luís; Silva, Elisabete. "Virulence genotypes of Escherichia coli canine isolates from pyometra, cystitis and fecal origin". Veterinary Microbiology 166 3-4 (2013): 590-594. http://dx.doi.org/10.1016/j.vetmic.2013.07.018.
    Accepted • 10.1016/j.vetmic.2013.07.018
  28. Murta, Daniel; Batista, Marta; Silva, Elisabete; Trindade, Alexandre; Henrique, Domingos; Duarte, António; Lopes-da-Costa, Luís. "Dynamics of Notch Pathway Expression during Mouse Testis Post-Natal Development and along the Spermatogenic Cycle". PLoS ONE 8 8 (2013): e72767. http://dx.doi.org/10.1371/journal.pone.0072767.
    Published • 10.1371/journal.pone.0072767
  29. Torres, A.; Chagas e Silva, J.; Diniz, P.; Lopes-da-Costa, L.. "Evaluation of treatments with hCG and carprofen at embryo transfer in a demi-embryo and recipient virgin heifer model". Animal 7 8 (2013): 1317-1322. http://dx.doi.org/10.1017/s1751731113000426.
    Published • 10.1017/s1751731113000426
  30. Torres, Ana; Batista, Mariana; Diniz, Patrícia; Mateus, Luisa; Lopes-da-Costa, Luís. "Embryo–luteal cells co-culture: an in vitro model to evaluate steroidogenic and prostanoid bovine early embryo–maternal interactions". In Vitro Cellular & Developmental Biology - Animal 49 2 (2013): 134-146. http://dx.doi.org/10.1007/s11626-012-9577-x.
    Published • 10.1007/s11626-012-9577-x
  31. Torres, A; Silva, J Chagas e; Deloche, MC; Humblot, P; Horta, AEM; Lopes-da-Costa, L. "Secondary Corpora Lutea Induced by hCG Treatment Enhanced Demi-Embryo Survival in Lactating High-Yielding Dairy Cows". Reproduction in Domestic Animals 48 4 (2013): 643-650. http://dx.doi.org/10.1111/rda.12138.
    Published • 10.1111/rda.12138
  32. Silva, E.; Henriques, S.; Brito, S.; Ferreira-Dias, G.; Lopes-da-Costa, L.; Mateus, L.. "Oestrous cycle-related changes in production of Toll-like receptors and prostaglandins in the canine endometrium". Journal of Reproductive Immunology 96 1-2 (2012): 45-57. http://dx.doi.org/10.1016/j.jri.2012.07.003.
    Published • 10.1016/j.jri.2012.07.003
  33. Torres, A; Silva, JF; Bernardes, N; Sales Luís, J; Lopes da Costa, L. "64, XX, SRY-negative, Testicular DSD Syndrome in a Lusitano Horse". Reproduction in Domestic Animals 48 3 (2012): e33-e37. http://dx.doi.org/10.1111/rda.12094.
    Published • 10.1111/rda.12094
  34. Batista, M.; Torres, A.; Diniz, P.; Mateus, L.; Lopes-da-Costa, L.. "Development of a bovine luteal cell in vitro culture system suitable for co-culture with early embryos". In Vitro Cellular & Developmental Biology - Animal 48 9 (2012): 583-592. http://dx.doi.org/10.1007/s11626-012-9552-6.
    Published • 10.1007/s11626-012-9552-6
  35. Trindade, Alexandre; Djokovic, Dusan; Gigante, Joana; Badenes, Marina; Pedrosa, Ana-Rita; Fernandes, Ana-Carina; Lopes-da-Costa, Luís; et al. "Low-Dosage Inhibition of Dll4 Signaling Promotes Wound Healing by Inducing Functional Neo-Angiogenesis". PLoS ONE 7 1 (2012): e29863. http://dx.doi.org/10.1371/journal.pone.0029863.
    Published • 10.1371/journal.pone.0029863
  36. KOWALCZYK-ZIEBA, Ilona; BORUSZEWSKA, Dorota; SAULNIER-BLACHE, Jean Sebastian; LOPES DA COSTA, Luis; JANKOWSKA, Katarzyna; SKARZYNSKI, Dariusz Jan; WOCLAWEK-POTOCKA, Izabela. "Lysophosphatidic Acid Action in the Bovine Corpus Luteum -An In Vitro Study". Journal of Reproduction and Development 58 6 (2012): 661-671. http://dx.doi.org/10.1262/jrd.2012-060.
    Published • 10.1262/jrd.2012-060
  37. Lopes-da-Costa, L.; Chagas e Silva, J.; Deloche, M.C.; Jeanguyot, N.; Humblot, P.; Horta, A.E.M.. "Effects of embryo size at transfer (whole versus demi) and early pregnancy progesterone supplementation on embryo growth and pregnancy-specific protein bovine concentrations in recipient dairy heifers". Theriogenology 76 3 (2011): 522-531. http://dx.doi.org/10.1016/j.theriogenology.2011.03.004.
    Published • 10.1016/j.theriogenology.2011.03.004
  38. Silva, E.; Leitão, S.; Henriques, S.; Kowalewski, M.P.; Hoffmann, B.; Ferreira-Dias, G.; Lopes da Costa, L.; Mateus, L.. "Gene transcription of TLR2, TLR4, LPS ligands and prostaglandin synthesis enzymes are up-regulated in canine uteri with cystic endometrial hyperplasia–pyometra complex". Journal of Reproductive Immunology 84 1 (2010): 66-74. http://dx.doi.org/10.1016/j.jri.2009.10.004.
    Published • 10.1016/j.jri.2009.10.004
  39. Robalo Silva, J.; Lopes-da-Costa, L.. "Avaliação da função reprodutiva do touro para sistemas de produção em extensivo: componentes da avaliação, protocolos e guia de interpretação". Revista Portuguesa de Buiatria 14 15 (2010): 39-54.
    Published
  40. Silva, E.; Leitão, S.; Tenreiro, T.; Pomba, C.; Nunes, T.; Lopes da Costa, L.; Mateus, L.. "Genomic and phenotypic characterization of Escherichia coli isolates recovered from the uterus of puerperal dairy cows". Journal of Dairy Science 92 12 (2009): 6000-6010. http://dx.doi.org/10.3168/jds.2009-2358.
    Published • 10.3168/jds.2009-2358
  41. Silva, E; Leitão, S; Ferreira-Dias, G; Lopes da Costa, L; Mateus, L. "Prostaglandin Synthesis Genes are Differentially Transcripted in Normal and Pyometra Endometria of Bitches". Reproduction in Domestic Animals 44 (2009): 200-203. http://dx.doi.org/10.1111/j.1439-0531.2009.01393.x.
    Published • 10.1111/j.1439-0531.2009.01393.x
  42. Silva, E.; Gaivão, M.; Leitão, S.; Jost, B.H.; Carneiro, C.; Vilela, C.L.; Lopes da Costa, L.; Mateus, L.. "Genomic characterization of Arcanobacterium pyogenes isolates recovered from the uterus of dairy cows with normal puerperium or clinical metritis". Veterinary Microbiology 132 1-2 (2008): 111-118. http://dx.doi.org/10.1016/j.vetmic.2008.04.033.
    Published • 10.1016/j.vetmic.2008.04.033
  43. Silva, E.; Gaivão, M.; Leitão, S.; Amaro, A.; Costa, L. Lopes da; Mateus, L.. "Blood COX-2 and PGES gene transcription during the peripartum period of dairy cows with normal puerperium or with uterine infection". Domestic Animal Endocrinology 35 3 (2008): 314-323. http://dx.doi.org/10.1016/j.domaniend.2008.07.001.
    Published • 10.1016/j.domaniend.2008.07.001
  44. Trindade, Alexandre; Ram Kumar, S.; Scehnet, Jeffrey S.; Lopes-da-Costa, Luis; Becker, Jorg; Jiang, Weidong; Liu, Ren; Gill, Parkash S.; Duarte, Antonio. "Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos". Blood 112 5 (2008): 1720-1729. http://dx.doi.org/10.1182/blood-2007-09-112748.
    Published • 10.1182/blood-2007-09-112748
  45. Chagas e Silva, J.; Diniz, P.; Lopes da Costa, L.. "Luteotrophic effect, growth and survival of whole versus half embryos and, their relationship with plasma progesterone concentrations of recipient dairy heifers". Animal Reproduction Science 104 1 (2008): 18-27. http://dx.doi.org/10.1016/j.anireprosci.2007.01.004.
    Published • 10.1016/j.anireprosci.2007.01.004
  46. Benedito, Rui; Trindade, Alexandre; Hirashima, Masanori; Henrique, Domingos; da Costa, Luis; Rossant, Janet; Gill, Parkash S; Duarte, António. "Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli". BMC Developmental Biology 8 1 (2008): 117. http://dx.doi.org/10.1186/1471-213x-8-117.
    Published • 10.1186/1471-213x-8-117
  47. Lopes-da-Costa, Luís. "Controlo da reprodução em efectivos bovinos de produção de carne". Revista Portuguesa de Buiatria 12 13 (2008): 5-14.
    Published
  48. Robalo Silva, J.; Agrícola, R.; Barbosa, M.; Lopes-da-Costa, L.. "Variação sazonal do volume testicular, da produção e qualidade do sémen e do comportamento sexual de cavalos Lusitanos". Revista Portuguesa de Ciências Veterinárias 102 561-562 (2007): 119-125.
    Published
  49. Chagas e Silva, J.; Lopes da Costa, L.. "Luteotrophic influence of early bovine embryos and the relationship between plasma progesterone concentrations and embryo survival". Theriogenology 64 1 (2005): 49-60. http://dx.doi.org/10.1016/j.theriogenology.2004.10.019.
    Published • 10.1016/j.theriogenology.2004.10.019
  50. Duarte, A.; Hirashima, M.; Benedito, R.; Trindade, A.; Diniz, P.; Bekman, E.; Costa, L.; Henrique, D.; Rossant, J.. "Dosage-sensitive requirement for mouse Dll4 in artery development". Genes & Development 18 20 (2004): 2474-2478. http://dx.doi.org/10.1101/gad.1239004.
    Published • 10.1101/gad.1239004
  51. Chagas e Silva, J.; Lopes da Costa, L.; Cidadão, R.; Robalo Silva, J.. "Plasma progesterone profiles, ovulation rate, donor embryo yield and recipient embryo survival in native Saloia sheep in the fall and spring breeding seasons". Theriogenology 60 3 (2003): 521-532. http://dx.doi.org/10.1016/s0093-691x(03)00045-1.
    Published • 10.1016/s0093-691x(03)00045-1
  52. Mateus, L.; Lopes da Costa, L.; Diniz, P.; Ziecik, A.J.. "Relationship between endotoxin and prostaglandin (PGE2 and PGFM) concentrations and ovarian function in dairy cows with puerperal endometritis". Animal Reproduction Science 76 3-4 (2003): 143-154. http://dx.doi.org/10.1016/s0378-4320(02)00248-8.
    Published • 10.1016/s0378-4320(02)00248-8
  53. Feliciano, M.C.; Mateus, L.; Lopes-da-Costa, L.. "Luteal function and metabolic parameters in relation to conception in inseminated dairy cattle". Revista Portuguesa de Ciências Veterinárias 98 545 (2003): 25-31.
    Published
  54. Quaresma, M.A.; Lopes-da-Costa, L.; Robalo Silva, J.. "Superovulation of Mertolengo cows with two FSH preparations (FSH-P and FOLLTROPIN)". Revista Portuguesa de Ciências Veterinárias 98 546 (2003): 81-84.
    Published
  55. Quaresma, M.A.; Lopes-da-Costa, L.; Horta, A.E.M.; Robalo Silva, J.. "Twinning induction and its effects on embryo-fetal and calf survival and, on reproductive efficiency of Mertolengo cattle kept at pasture". Revista Portuguesa de Ciências Veterinárias 99 550 (2003): 109-115.
    Published
  56. Chagas e Silva, J; Lopes da Costa, L; Robalo Silva, J. "Plasma progesterone profiles and factors affecting embryo-fetal mortality following embryo transfer in dairy cattle". Theriogenology 58 1 (2002): 51-59. http://dx.doi.org/10.1016/s0093-691x(02)00906-8.
    Published • 10.1016/s0093-691x(02)00906-8
  57. Mateus, L; da Costa, L Lopes; Carvalho, H; Serra, P; Robalo Silva, J. "Blood and Intrauterine Leukocyte Profile and Function in Dairy Cows that Spontaneously Recovered from Postpartum Endometritis". Reproduction in Domestic Animals 37 3 (2002): 176-180. http://dx.doi.org/10.1046/j.1439-0531.2002.00351.x.
    Published • 10.1046/j.1439-0531.2002.00351.x
  58. Mateus, L; Lopes da Costa, L; Alfaro Cardos, JJ; Robalo Silva, J. "Treatment of Unobserved Oestrus in a Dairy Cattle Herd with Low Oestrous Detection Rate up to 60 days Post-partum". Reproduction in Domestic Animals 37 1 (2002): 57-60. http://dx.doi.org/10.1046/j.1439-0531.2002.00330.x.
    Published • 10.1046/j.1439-0531.2002.00330.x
  59. Mateus, L; Lopes da Costa, L; Bernardo, F; Robalo Silva, J. "Influence of Puerperal Uterine Infection on Uterine Involution and Postpartum Ovarian Activity in Dairy Cows". Reproduction in Domestic Animals 37 1 (2002): 31-35. http://dx.doi.org/10.1046/j.1439-0531.2002.00317.x.
    Published • 10.1046/j.1439-0531.2002.00317.x
  60. Chagas e Silva, J; Lopes da Costa, L; Robalo Silva, J. "Embryo yield and plasma progesterone profiles in superovulated dairy cows and heifers". Animal Reproduction Science 69 1-2 (2002): 1-8. http://dx.doi.org/10.1016/s0378-4320(01)00172-5.
    Published • 10.1016/s0378-4320(01)00172-5
  61. Mateus, L.; Lopes-da-Costa, L.. "Peripartum blood concentrations of calcium, phosphorus and magnesium in dairy cows with normal puerperium or puerperal endometritis". Revista Portuguesa de Ciências Veterinárias 97 541 (2002): 35-38.
    Published
  62. Lopes-da-Costa, L.; Chagas e Silva, J.; Diniz, P.; Cidadão, R.. "Preliminary report on sexing bovine pre-implantation embryos under the conditions of Portugal". Revista Portuguesa de Ciências Veterinárias 97 542 (2002): 95-98.
    Published
  63. Lopes da Costa, L.; Chagas e Silva, J.; Robalo Silva, J.. "Superovulatory response, embryo quality and fertility after treatment with different gonadotrophins in native cattle". Theriogenology 56 1 (2001): 65-77. http://dx.doi.org/10.1016/s0093-691x(01)00543-x.
    Published • 10.1016/s0093-691x(01)00543-x
  64. Marques, C.M.; Baptista, M.C.; Pereira, R.M.; Vasques, M.I.; Lopes-da-Costa, L.F.; Horta, A.E.M.. "Influência do sémen de diferentes touros sobre a taxa de fertilização in vitro e de desenvolvimento de embriões em co-cultura". Revista Portuguesa de Zootecnia ano II 2 (1995): 103-110.
    Published
  65. Lopes-da-Costa, L.F.; Limão Oliveira, J.M.. "Exame ultrassonográfico do tracto genital na cadela e gata". Revista Portuguesa de Ciências Veterinárias 87 503 (1992): 120-134.
    Published
Thesis / Dissertation
  1. Lopes-da-Costa, Luís. "Estudo sobre a utilização das raças bovinas autóctones portuguesas Alentejana e Mertolenga como dadoras e receptoras de embriões". PhD, Universidade de Lisboa Faculdade de Medicina Veterinária, 1995.
  2. Lopes-da-Costa, Luís. "Transferência de embriões em bovinos". Master, Universidade de Lisboa Faculdade de Medicina Veterinária, 1990.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2011/10 Identification of genes and their expression in mammalian embryos: applications in research and medicine V Congresso da Sociedade Portuguesa de Ciências Veterinárias
Sociedade Portuguesa de Ciências Veterinárias (Santarém, Portugal)
2006/02 Biotecnologia da Reprodução: Do Modelo Biomédico à Inovação Empresarial Simpósio “A Investigação da Universidade Técnica de Lisboa”
Universidade Técnica de Lisboa (Lisboa, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022/03/01 - Current Uterine and mammary inflammation proresolving mechanisms in postpartum dairy cows
Supervisor
 Ciências Veterinárias (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2020/02/01 - Current Genetic polymorphisms of Heat Shock Proteins and mechanisms of thermotolerance in different beef cattle breeds in heat stress: A basis for the selection for reproductive efficiency in a climatic change scenario?
Co-supervisor
 Ciências Veterinárias (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2019 - Current Biotechnological Innovative Solutions for the Control of Bovine Genital Campylobacteriosis
Co-supervisor
 Pós-Doutoranda (Other)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2017 - Current Effects of Bovine Venereal Campylobacteriosis and Bovine Viral Diarrohea interaction on beef herd reproductive efficiency (FCT Scholarship: SFRH/BD/130923/2017)
Co-supervisor
 Ciências Veterinárias (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2017 - Current Understanding the role of Notch signaling components in sperm function (FCT Scholarship: SFRH/BD/130536/2017)
Supervisor
 Ciências Veterinárias (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2013 - Current The Notch cellular pathway and gamete/embryo-maternal interactions relevant for pregnancy establishment in the bovines species (FCT Scholarship: SFRH/BD/90463/2012)
Co-supervisor
 Ciências Veterinárias (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2009 - 2016 In vivo evaluation of the role of Delta-like 4/Notch signaling in the development of intestinal tumors
Co-supervisor
 Ciências Veterinárias (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2010 - 2014 Notch signaling, genital remodeling and reproductive function
Supervisor
 Ciências Veterinárias (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2008 - 2012 Embryo-maternal interactions leading to embryonic development and survival in the bovine : role of progesterone and prostaglandins
Supervisor
 Ciências Veterinárias (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2004 - 2008 Analysis of Dll4 function in the regulation of embryonic angiogenesis and tumoral neo-angiogenesis
Co-supervisor
 Ciência e Tecnologia Animal (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2004 - 2008 Study of the role of Delta 4 gene in the regulation of angiogenesis
Co-supervisor
 Ciência e Tecnologia Animal (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2003 - 2007 Superovulation and embryo transfer in dairy ruminants in Portugal
Supervisor
 Ciências Veterinárias (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2000 - 2003 Relationship between plasma concentrations of progesterone, metabolic markers and fertility in inseminated dairy cattle
Supervisor
 Produção Animal (Master)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
1998 - 2002/11/25 Use of techniques of estrus control and twinning induction in Mertolengo cattle reared in the traditional production system
Co-supervisor
 Ciências Veterinárias (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
1999 - 2002 Development and testing of a conditional transgenesis vector for a new homologous Delta gene of mice, mDll4
Co-supervisor
 Produção Animal (Master)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
1998 - 2002 Studies on the establishment and persistence of the puerperal uterine infection in dairy cows
Supervisor
 Ciências Veterinárias (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Distinctions

Other distinction

2009 Honor Distinction (Menção Honrosa) of Prize UTL - Santander Totta
Universidade de Lisboa, Portugal