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Maria João Penetra graduated in 2019 in Human Biology from Universidade de Évora. During this 1st cycle of studies, she had the opportunity to contact different scientific areas, such as Anatomophysiology, Cellular and Molecular Biology, Microbiology, and Pharmacology, among many others. In addition, she also had her first contact with scientific research after a curricular internship in the Laboratory of Animal Physiology of MED - Instituto Mediterranean Agricultura, Ambiente e Desenvolvimento, entitled "Relationship between salivary amylase and pH levels and dietary habits: focus on Mediterranean diet", obtaining 18 values (out of 20). In 2021, she completed a Master's Degree in Biopharmaceutical Sciences from the Faculdade de Farmácia -Universidade de Lisboa, with an average of 18 values. During her master's thesis, developed at iMed - Research Institute for Medicines, entitled "In vitro and in vivo evaluation of new hybrid molecules following its incorporation into a lipid-based nanosystem for melanoma management", she gained experience in the area of cell culture, animal models, and drug delivery systems, obtaining a final classification of 20 values (out of 20). Simultaneously with her master's degree, she also carried out a Post-Graduate Course on Updating Science in Laboratory Animals. She participated in 4 Scientific Conferences with three Posters and one Oral Communication. She accounts for 3 published articles in specialised journals as a co-author and 1 submitted article at Journal of Cultural Heritage as principal author. Currently, she is taking a PhD in Biochemistry in University of Évora and has a research fellowship within the scope of the project ROADMAP - Research On Antonio De Holanda Miniatures Artistic Production (PTDC/ART-HIS/0985/2021), financed by national funds through Fundação para a Ciência e a Tecnologia (FCT/MCTES), contacting with techniques such as Next-Generation Sequencing (NGS), and analysis of ancient DNA from parchments.
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Identification

Personal identification

Full name
Maria João Maia Penetra
Date of birth
1998/08/20
Gender
Female

Citation names

  • Penetra, Maria João

Author identifiers

Ciência ID
0B12-FB4A-8B57
ORCID iD
0000-0003-4730-1225
Scopus Author Id
57262721900

Email addresses

  • mariajpenetra@gmail.com (Professional)

Websites

  • www.linkedin.com/in/maria-joão-penetra-943006183 (Professional)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Natural sciences - Biological Sciences - Microbiology
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2022/09 - 2025
Ongoing
 Curso de Doutoramento em Bioquímica (Doutoramento)
Universidade de Évora, Portugal
2020 - 2021
Concluded
 Curso Pós-Graduado de Atualização de Ciências em Animais de Laboratório Categoria B (Pós-Graduação)
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Teórico - 83%; Practico- 18
2019 - 2021
Concluded
 Ciências Biofarmacêuticas (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"In vitro and in vivo evaluation of new hybrid molecules following its incorporation into a lipid-based nanosystem for melanoma management" (THESIS/DISSERTATION)
 18
2016 - 2019
Concluded
 Biologia Humana (Licenciatura)
Universidade de Évora, Portugal
"Relationship between salivary amylase and pH levels and dietary habits: focus on the Mediterranean diet" (THESIS/DISSERTATION)
 15
Affiliation

Science

Category
Host institution 		Employer
2022/06/01 - Current Research Trainee (Research) Universidade de Évora, Portugal
Laboratório Hercules Herança Cultural Estudos e Salvaguarda, Portugal
2020/09 - 2021/12 Research Trainee (Research) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/02 - 2019/06 Research Trainee (Research) Universidade de Évora Instituto Mediterrâneo para a Agricultura Ambiente e Desenvolvimento, Portugal
Universidade de Évora, Portugal
Projects

Grant

Designation Funders
2022/06/01 - Current ROADMAP - Research On Antonio De Holanda Miniatures Artistic Production
PTDC/ART-HIS/0985/2021
Research Fellow
Fundação para a Ciência e a Tecnologia
Ongoing

Contract

Designation Funders
2023/07 - 2023/07 H2020-INFRAIA-2019-1-871034- IPERION-HS- Integrating Platforms for the European Research Infrastructure ON Heritage Science
871034
Research Fellow
Outputs

Publications

Conference abstract
  1. Penetra, Maria João; Miguel, Catarina; Caldeira, A Teresa. Corresponding author: Caldeira, A Teresa. "To be or not to be - On the use of biosignatures approaches for the analysis of parchment origin". Paper presented in Technart -International conference on analytical techniques in art and cultural heritage, Lisboa, 2023.
  2. Penetra, Maria João; Candeias, António; Miguel, Catarina; Caldeira, A Teresa. Corresponding author: Caldeira, A Teresa. "The connection between animal origin of historical parchment and microbiome". Paper presented in MicroBiotec 2023 - Congress of Microbiology and Biotechnology 2023, 2023.
    Submitted
  3. Penetra, Maria João; Francisco, Ana Paula; O. Pinho, Jacinta; Mendes, Eduarda; Rodrigues, Cecília MP; Amaral, Joana; Gaspar, Maria Manuela. Corresponding author: Penetra, Maria João. "Liposomes as a tool to potentiate the antitumor effect of a new hybrid molecule: in vitro and in vivo studies". Paper presented in 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting, 2022.
  4. Penetra, Maria João; Francisco, Ana Paula; O. Pinho, Jacinta; Mendes, Eduarda; Rodrigues, Cecília MP; Amaral, Joana; Gaspar, Maria Manuela. Corresponding author: Penetra, Maria João. "In vitro and in vivo evaluation of new hybrid molecules following its incorporation to a lipid-based nanosystem for the management of melanoma". Paper presented in 1st Symposium on Advanced Technologies for Drug Delivery 2021, Lisboa, 2021.
    Published
  5. Penetra, Maria João; Francisco, Ana Paula; Pinho, Jacinta; Mendes, Eduarda; Rodrigues, Cecília MP; Amaral, Joana; Gaspar, Maria Manuela. Corresponding author: Penetra, Maria João. "Improved selectivity and in vitro cytotoxic effects of hybrid molecules via liposomal delivery as a tool to fight melanoma". Paper presented in iMed.ULisboa Meeting 2021, Lisboa, 2021.
    Published
Conference poster
  1. Penetra, Maria João; Miguel, Catarina; Caldeira, A Teresa. Corresponding author: Caldeira, A Teresa. "To be or not to be - On the use of biosignatures approaches for the analysis of parchment origin". Paper presented in Technart -International conference on analytical techniques in art and cultural heritage, 2023.
  2. Penetra, Maria João; Francisco, Ana Paula; Pinho, Jacinta; Mendes, Eduarda; Rodrigues, Cecília MP; Amaral, Joana; Gaspar, Maria Manuela. "In vitro and in vivo evaluation of new hybrid molecules following its incorporation to a lipid-based nanosystem for the management of melanoma". Paper presented in 1st Symposium on Advanced Technologies for Drug Delivery 2021, 2021.
  3. Penetra, Maria João; Francisco, Ana Paula; Pinho, Jacinta; Mendes, Eduarda; Rodrigues, Cecília MP; Amaral, Joana; Gaspar, Maria Manuela. "Improved selectivity and in vitro cytotoxic effects of hybrid molecules via liposomal delivery as a tool to fight melanoma". Paper presented in iMed.ULisboa Meeting 2021, 2021.
Journal article
  1. Penetra, Maria João; Candeias, António; Miguel, Catarina; Caldeira, A Teresa. Corresponding author: Caldeira, A Teresa. ""Deciphering parchment origin and microbiome through biocodicology" CULHER-D-23-00894 (Under publication)". Journal of Cultural Heritage (2024):
    Submitted
  2. Mariana Matias; Jacinta O. Pinho; Maria João Penetra; Gonçalo Campos; Catarina Pinto Reis; Maria Manuela Gaspar. "The Challenging Melanoma Landscape: From Early Drug Discovery to Clinical Approval". Cells 10 11 (2021): 3088-3088. https://doi.org/10.3390/cells10113088.
    10.3390/cells10113088
  3. Granada, Margarida; Mendes, Eduarda; Perry, Maria Jesus; Penetra, Maria João; Gaspar, Maria Manuela; Pinho, Jacinta O.; Serra, Sofia; António, Catarina Teixeira; Francisco, Ana Paula. "Sulfur Analogues of Tyrosine in the Development of Triazene Hybrid Compounds: A New Strategy against Melanoma". ACS Medicinal Chemistry Letters 12 11 (2021): 1669-1677. http://dx.doi.org/10.1021/acsmedchemlett.1c00252.
    10.1021/acsmedchemlett.1c00252
  4. Louro, Teresa; Simões, Carla; Penetra, Maria João; Carreira, Laura; Castelo, Paula Midori; Luis, Henrique; Moreira, Pedro; Lamy, Elsa. "Relationship between Mediterranean Diet Adherence and Saliva Composition". Nutrients 13 4 (2021): 1246. http://dx.doi.org/10.3390/nu13041246.
    Published • 10.3390/nu13041246
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/04/21 Liposomes as a tool to potentiate the antitumor effect of a new hybrid molecule: in vitro and in vivo studies 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting
(Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/09/21 - Current Member of the Organizing Committee of the 2nd International Conference on Drugs&Colors in History: From the Past to the Present (2023/09/21 - 2023/09/22)
Conference (Member of the Organising Committee)
 Universidade de Évora, Portugal

Laboratório Hercules Herança Cultural Estudos e Salvaguarda, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/09/29 - 2023/09/29 Noite Europeia dos Investigadores - Ciência Para Todos, Sustentabilidade e Inclusão 2023 - Atividade "Sustentabilidade e Inclusão através do Património. O que se faz no Laboratório HERCULES e Microrganismos do Património: Biotecnologia Verde para um Futuro Sustentável
Meeting
 Noite Europeia dos Investigadores - Ciência Para Todos, Sustentabilidade e Inclusão
Universidade de Évora, Portugal
2022 - 2022 Noite Europeia dos Investigadores - Ciência para todos, Sustentabilidade e inclusão 2022 - Atividade "Os Microrganismos do património: Soluções Biotecnológicas verdes, Ecológicas e Sustentáveis"
Meeting

Scientific expedition

Activity description Institution / Organization
2023/07 - 2023/07 H2020-INFRAIA-2019-1-871034- IPERION-HS- Integrating Platforms for the European Research Infrastructure ON Heritage Science. The Laboratório HERCULES was present at the MUDEC- Museo delle Culture of Milan - working on the MOLAB project Pre-Hispanic Andean Wooden Boards at the Museo delle Culture of Milan: A Multi-Modal, to study two rare pre-Hispanic Andean wooden boards held in the collections of the MUDEC . The HERCULES Laboratory team developed a biomolecular analyses to determine the possible presence of biodeteriogenic microorganisms.
2022/11 - 2022/11 Mission to the British Library to study and analyze manuscripts of the Renaissance period attributed to António de Holanda, within the scoop of the project "ROADMAP - Research On Antonio De Holanda Miniatures Artistic Production" (PTDC/ART-HIS/0985/2021), financed by national funds through Fundação para a Ciência e a Tecnologia (FCT/MCTES). Laboratório Hercules Herança Cultural Estudos e Salvaguarda, Portugal

Universidade de Évora, Portugal
Distinctions

Award

2013 High School Excellence Award - Agrupamento de escolas de Viana do Alentejo