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Patrícia S. Guerreiro obtained her PhD in Pharmacy (2016) from the Faculty of Pharmacy, Universidade de Lisboa (FF.ULisboa, PT) with a multidisciplinary work developed in the fields of DNA damage repair and anticancer therapy resistance. She has +11 years of research experience leading and providing technical support to R&D projects in the fields of drug discovery and preclinical development of novel breast cancer therapies, identification of novel druggable targets and biomarkers of cancer progression, characterization of anti-infective drugs and materials, and delivery of biologics across physiological barriers to treating brain diseases, both in academic and CRO-like settings. From February 2017 to May 2020, Patrícia S. Guerreiro was a postdoctoral fellow at IGC/IPATIMUP/i3S within the frame of the CANCEL STEM R&D consortium (Portugal 2020/FCT funding - POCI-01-0145-FEDER-016390), where she exploited the interplay between the cell-cell adhesion molecule P-cadherin and the actin cytoskeleton in the acquisition of cancer stem-like cells in breast cancer models. To translate knowledge into actionable solutions, Patrícia S. Guerreiro joined the Discovery department of VectorB2B (CRO-like CoLAB) as a Biochemistry Scientist (June 2020-August 2022). By providing consultancy and customer-tailored drug discovery and analytical solutions for Biotech and Pharmaceutical companies, she developed a business-driven, entrepreneurial and customer-centric mindset while developing strategical interfaces with a network of national and international cross-functional academic and industry stakeholders for fostering knowledge valorization. In September 2022, Patrícia S. Guerreiro integrated the FCiências.ID – Associação para a Investigação e Desenvolvimento de Ciências as an Innovation Expert, where she is focused on building collaborations with national and international partners and supporting funding for translating scientific ideas and projects of Centro de Química Estrutural (CQE) - Associate Laboratory Institute of Molecular Sciences (IMS) into value chains with high potential.
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Identification

Personal identification

Full name
PATRÍCIA ISABEL DA SILVA GUERREIRO
Gender
Female

Citation names

  • GUERREIRO, PATRÍCIA S.

Author identifiers

Ciência ID
0C13-F347-FA6C
ORCID iD
0000-0001-8972-3333
Researcher Id
AAE-6039-2020
Scopus Author Id
57195447344

Email addresses

  • piguerreiro@ciencias.ulisboa.pt (Professional)

Addresses

  • Avenida Professor Gama Pinto nº.2 , 1649-003, Lisboa, Lisboa, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Medical and Health Sciences - Health Sciences - Infectious Diseases
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Natural sciences - Biological Sciences - Biochemical Research Methods

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2021/09/11 - 2021/11/13
Concluded
 Regulatory Affairs & Technical Direction (Pós-Graduação)
Invictus Sciences, Portugal
2020/10/14 - 2021/04/17
Concluded
 Certification Program for Medical Science Liaison (Pós-Graduação)
Universidade Católica Portuguesa Instituto de Ciências da Saúde, Portugal
 17 (out of 20)
2011/05/01 - 2016/12/14
Concluded
 Pharmacy (specialty of Toxicology) (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
"Modulation of Human Apurinic/apyrimidinic Endonuclease 1 (APE1) Functions for Breast Cancer Therapy" (THESIS/DISSERTATION)
 Distinction and Honours
2004/09 - 2009/11/26
Concluded
 Pharmaceutical Sciences (Mestrado integrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Novas Abordagens na Terapia Antiangiogénica no Cancro (bibliographic revision as part of the internship of the Master Integrated degree in Pharmaceutical Sciences)" (THESIS/DISSERTATION)
 16 (out of 20)
Affiliation

Science

Category
Host institution 		Employer
2022/09/01 - Current Science and Technology Management Universidade de Lisboa Centro de Química Estrutural, Portugal
FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal
2020/01/01 - 2020/05/20 Contracted Researcher (Research) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018/01/15 - 2019/12/31 Postdoc (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/02/01 - 2018/01/12 Postdoc (Research) Instituto Gulbenkian de Ciência, Portugal

Others

Category
Host institution 		Employer
2020/06/01 - 2022/08/31 Scientist (Discovery) VectorB2B, Portugal
VectorB2B, Portugal
2011/05/01 - 2016/12/14 PhD student (FCT Scholarship: SFRH/BD/70293/2010) Universidade de Lisboa Faculdade de Farmácia, Portugal
Projects

Grant

Designation Funders
2018/06/01 - 2021/05/31 STEMACT - Actin cytoskeleton in breast cancer stem cells (CSCs) biology: insights into tumor progression and anticancer therapy resistance
STEMACT
Principal investigator
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto Instituto de Patologia e Imunologia Molecular
Ongoing
2017/02/01 - 2020/12/31 Tackling CANcer STEM CELls: a challenge and an opportunity to advance in anti-cancer therapy
POCI-01-0145-FEDER-016390
Post-doc Fellow
Instituto Gulbenkian de Ciência, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia, co-financed by Fundo Europeu de Desenvolvimento Regional (FEDER) through Programa Operacional Competitividade e Internacionalização (POCI)
Ongoing

Other

Designation Funders
2011/05/01 - 2015/04/30 Modulation of Human Apurinic/apyrimidinic Endonuclease 1 (APE1) Functions for Breast Cancer Therapy
SFRH/BD/70293/2010
PhD Student Fellow
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Rodrigues, António S.; Gomes, Bruno C.; Martins, Célia; Gromicho, Marta; Oliveira, Nuno G.; GUERREIRO, PATRÍCIA S.; Rueff, José. "DNA Repair and Resistance to Cancer Therapy". In New Research Directions in DNA Repair, edited by Clark Chen, 489-528. Rijeka, Croatia: InTech, 2013.
    Published • 10.5772/53952
Conference abstract
  1. Costa, Joao G.; Saraiva, Nuno; GUERREIRO, PATRÍCIA S.; Castro, Matilde; Batinic-Haberle, Ines; Oliveira, Nuno G.; Fernandes, Ana S.. "Viability and migration of human renal cancer cells upon treatment with a superoxide dismutase mimic". Paper presented in 53rd Congress of the European Societies of Toxicology (Eurotox 2017), Bratislava, 2017.
    Published • https://doi.org/10.1016/j.toxlet.2017.07.312
  2. GUERREIRO, PATRÍCIA S.; Corvacho, E.; Miranda, Joana P.; Costa, J.; Fernandes, A.S.; Castro, M.; Oliveira, N. G.. "Targeting APE1 redox function with E3330: Effects on the migration of MDA-MB-231 cells". Paper presented in 51st Congress of the European Societies of Toxicology (EUROTOX), Porto, 2015.
    Published • doi.org/10.1016/j.toxlet.2015.08.713
  3. Costa, Joao; Saraiva, Nuno; GUERREIRO, PATRÍCIA S.; Miranda, Joana P.; Batinic-Haberle, Ines; Castro, Matilde; Oliveira, Nuno G.; Fernandes, Ana S.. "Effect of the SOD mimetic MnTnHex-2-PyP on the generation of ROS and cytotoxicity induced by ochratoxin A". Paper presented in 51st Congress of the European Societies of Toxicology (Eurotox 2015), Porto, 2015.
    Published • https://doi.org/10.1016/j.toxlet.2015.08.840
  4. GUERREIRO, PATRÍCIA S.; Miranda, Joana P.; Fernandes, Ana S.; Costa, Joao G.; Castro, M.; Oliveira, Nuno G.. "Effect of APE1 inhibitors on the cytotoxicity and genotoxicity of doxorubicin in MDA-MB-231 cells". Paper presented in 49th Congress of the European Societies of Toxicology (Eurotox 2013), Interlaken, 2013.
    Published • https://doi.org/10.1016/j.toxlet.2013.05.120
  5. Costa, Joao G.; Fernandes, Ana S.; Guerreiro, Patrícia S.; Filipe, Elysse; Miranda, Joana P.; Castro, Matilde; Oliveira, Nuno G.. "Induction of micronuclei and cytotoxic effects of ochratoxin A in Vero cells". Paper presented in 49th Congress of the European Societies of Toxicology (Eurotox 2013), Interlaken, 2013.
    Published • https://doi.org/10.1016/j.toxlet.2013.05.214
  6. Fernandes, Ana S.; Flórido, Ana; Cipriano, Madalena; Batinic-Haberle, Ines; Miranda, Joana P.; Saraiva, Nuno; GUERREIRO, PATRÍCIA S.; Castro, Matilde; Oliveira, Nuno G.. "Combined effect of the SOD mimic MnTnHex-2-PyP5+ and doxorubicin on the migration and invasiveness of breast cancer cells". Paper presented in 49th Congress of the European Societies of Toxicology (Eurotox 2013), Interlaken, 2013.
    Published • https://doi.org/10.1016/j.toxlet.2013.05.052
  7. Fernandes, Ana S.; Cipriano, Madalena; Costa, Judite; Cabral, Maria F.; Miranda, Joana P.; Oliveira, Nuno G.; GUERREIRO, PATRÍCIA S.; Castro, Matilde. "Beneficial effects of the redox-active complex Cu[15]pyN5 in doxorubicin-treated breast cancer cells". Paper presented in 16th SFRRI, biennial meeting, London, 2012.
    Published • https://doi.org/10.1016/j.freeradbiomed.2012.08.251
  8. Oliveira, Nuno G.; Magro, Ines; Fernandes, Ana S.; Miranda, Joana P.; GUERREIRO, PATRÍCIA S.; Castro, Matilde. "Effect of DNA repair inhibitors on the cytotoxicity induced by glycidamide". Paper presented in 48th Congress of the European Societies of Toxicology (Eurotox 2012), Stockholm, 2012.
    Published • https://doi.org/10.1016/j.toxlet.2012.03.410
Conference poster
  1. GUERREIRO, PATRÍCIA S.; Gonçalves, Margarida; Morais-de-Sá, Eurico; Paredes, Joana; Janody, Florence. "Cytoskeletal dynamics links P-cadherin-induced cancer stem-like features to genomic activity". Paper presented in 8th i3S Annual Meeting, 2019.
  2. Jain, Praachi B.; GUERREIRO, PATRÍCIA S.; Janody, Florence. "The spectraplakin Dystonin suppressestumourigenesis through antagonizingthe activity of the YAP/TAZ oncogenes". Paper presented in DGZ 2018 - International Meeting ofthe German Society for Cell Biology“Concepts of Cell Organization andDynamics”, 2018.
  3. Costa, Joao G.; Saraiva, Nuno; GUERREIRO, PATRÍCIA S.; Castro, Matilde; Batinic-Haberle, Ines; Oliveira, Nuno G.; Fernandes, Ana S.. "Viability and migration of human renal cancer cells upon treatment with a superoxide dismutase mimic". Paper presented in 53rd Congress of the European Societies of Toxicology (Eurotox 2017), 2017.
    https://doi.org/10.1016/j.toxlet.2017.07.312
  4. Costa, Joao G.; Saraiva, Nuno; GUERREIRO, PATRÍCIA S.; Miranda, Joana P.; Batinic-Haberle, Ines; Castro, Matilde; Oliveira, Nuno G.; Fernandes, Ana S.. "Effect of the SOD mimetic MnTnHex-2-PyP on the generation of ROS and cytotoxicity induced by ochratoxin A.". Paper presented in 51st Congress of the European Societies of Toxicology (Eurotox 2015), 2015.
  5. GUERREIRO, PATRÍCIA S.; Corvacho, Eduardo; Miranda, Joana P.; Costa, João G.; Fernandes, Ana S.; Castro, Matilde; Oliveira, Nuno G.. "Targeting APE1 redox function with E3330: effects on the migration of MDA-MB-231 cells". Paper presented in 51st Congress of the European Societies of Toxicology (Eurotox 2015), 2015.
  6. GUERREIRO, PATRÍCIA S.; Corvacho, Eduardo; Costa, Joao G.; Fernandes, Ana S.; Castro, Matilde; Saraiva, Nuno; Miranda, Joana P.; Oliveira, Nuno G.. "Evaluation of an inhibitor of APE1 redox function in docetaxel-treated MDA-MB-231 cells.". Paper presented in 7th iMed.ULisboa Postgraduate Students Meeting, 2015.
  7. Costa, Joao G.; Saraiva, Nuno; GUERREIRO, PATRÍCIA S.; Miranda, Joana P.; Castro, Matilde; Oliveira, Nuno G.; Fernandes, Ana S.. "Cytotoxicity, genotoxicity and reactive oxygen species production by ochratoxin A in monkey kidney cells". Paper presented in II Jornadas Ibéricas de Toxicologia, 2014.
  8. Costa, Joao G.; GUERREIRO, PATRÍCIA S.; Saraiva, Nuno; Miranda, Joana P.; Castro, Matilde; Oliveira, Nuno G.; Fernandes, Ana S.. "Cytotoxicity, genotoxicity and ROS production by ochratoxin A in Vero cells". Paper presented in Summer School “Biochemical Basis of Healthy Aging, 2014.
  9. GUERREIRO, PATRÍCIA S.; Corvacho, Eduardo; Miranda, Joana P.; Costa, João G.; Fernandes, Ana S.; Castro, Matilde; Oliveira, Nuno G.. "Targeting APE1 redox activity to modulate the migration of MDA-MB-231 breast cancer cells". Paper presented in 6th iMed.ULisboa Postgraduate Students Meeting, 2014.
  10. GUERREIRO, PATRÍCIA S.; Miranda, Joana P.; Estácio, Sílvia G.; Antunes, Fernando; Costa, Joao G.; Fernandes, Ana S.; Castro, Matilde; Guedes, Rita C.; Oliveira, Nuno G.. "Small-molecule inhibitors of APE1 DNA repair activity as potential sensitizers of chemotherapy". Paper presented in The DNA damage response in cell physiology and disease - EMBO Conference, 2013.
  11. Fernandes, Ana S.; Flórido, Ana; Cipriano, Madalena; Batinic-Haberle, Ines; Miranda, Joana; Saraiva, Nuno; GUERREIRO, PATRÍCIA S.; Castro, Matilde; Oliveira, Nuno G.. "Combined effect of the SOD mimic MnTnHex-2-PyP5+ and doxorubicin on the migration and invasiveness of breast cancer cells". Paper presented in 49th Congress of the European Societies of Toxicology (Eurotox 2013), 2013.
  12. Costa, Joao G.; Fernandes, Ana S.; GUERREIRO, PATRÍCIA S.; Filipe, Elysse; Miranda, Joana P.; Castro, Matilde; Oliveira, Nuno G.. "Induction of micronuclei and cytotoxic effects of ochratoxin A in Vero cells". Paper presented in 49th Congress of the European Societies of Toxicology (Eurotox 2013), 2013.
  13. GUERREIRO, PATRÍCIA S.; Miranda, Joana P.; Fernandes, Ana S.; Costa, João G.; Castro, Matilde; Guerreiro, Nuno G.. "Effect of APE1 inhibitors on the cytotoxicity and genotoxicity of doxorubicin in MDA-MB-231 cells". Paper presented in 49th Congress of the European Societies of Toxicology (Eurotox 2013), 2013.
  14. Ribeiro, Isabel A.; Faustino, Célia M. C.; Frade, Raquel; GUERREIRO, PATRÍCIA S.; Bronze, Maria Rosário; Castro, Matilde F.; Ribeiro, Maria HL. "Purification of sophorolipids produced by Starmerella bombicola and their individual cytotoxic effect towards MDA-MB-231 breast cancer cells". Paper presented in 4th Post-Graduate iMed.UL Students Meeting, 2012.
  15. GUERREIRO, PATRÍCIA S.; Estácio, Sílvia G.; Miranda, Joana P.; Fernandes, Ana S.; Castro, Matilde; Guedes, Rita; Oliveira, Nuno G.. "APE1 inhibitors as potential sensitizing agents for chemotherapeutic drugs". Paper presented in 4th Post-Graduate iMed.UL Students Meeting, 2012.
  16. Fernandes, Ana S.; Cipriano, Madalena; Flórido, Ana C.; Costa, Judite; Cabral, Maria F.; Miranda, Joana P.; Oliveira, Nuno G.; GUERREIRO, PATRÍCIA S.; Castro, Matilde. "Beneficial effects of the redox-active complex Cu[15]pyN5 in doxorubicin-treated breast cancer cells". Paper presented in 16th SFRRI, biennial meeting, 2012.
  17. Oliveira, Nuno G.; Magro, Ines; Fernandes, Ana S.; Miranda, Joana P.; GUERREIRO, PATRÍCIA S.; Castro, Matilde. "Effect of DNA repair inhibiors on the cytotoxicity induced by glycidamide". Paper presented in 48th Congress of the European Societies of Toxicology (Eurotox 2012), 2012.
  18. GUERREIRO, PATRÍCIA S.; Fernandes, Ana S.; Miranda, Joana P.; Castro, Matilde. "APE1 inhibitor methoxyamine on the cytotoxicity induced by doxorubicin in metastatic breast cancer cells". Paper presented in 3rd Post-Graduate iMed.UL Students Meeting, 2011.
Journal article
  1. Lídia Faria; Sara Canato; Teles Jesus, Tito; Gonçalves, Margarida; GUERREIRO, PATRÍCIA S.; Lopes, Carla S.; Isabel Meireles; et al. "Activation of the actin/MRTF-A/SRF signalling pathway in pre-malignant mammary epithelial cells by P-cadherin is essential for transformation". bioRxiv (2022): https://doi.org/10.1101/2022.02.26.481995.
    Open access • Published
  2. Selvaggio, Gianluca; Canato, Sara; Pawar, Archana; Monteiro, Pedro T.; GUERREIRO, PATRÍCIA S.; Brás, M. M.; Janody, Florence; Chaouiya, Claudine. "Hybrid epithelial-mesenchymal phenotypes are controlled by microenvironmental factors". Cancer Research 80 11 (2020): 2407-2420.
    Open access • Published • 10.1158/0008-5472.CAN-19-3147
  3. Jain, Praachi B.; GUERREIRO, PATRÍCIA S.; Canato, Sara; Janody, Florence. "The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis". Scientific Reports 9 1 (2019): 19843. http://dx.doi.org/10.1038/s41598-019-56296-z.
    Open access • Published • 10.1038/s41598-019-56296-z
  4. GUERREIRO, PATRÍCIA S.; Corvacho, Eduardo; Costa, João G.; Saraiva, Nuno; Fernandes, Ana S.; Castro, Matilde; Miranda, Joana P.; Oliveira, Nuno G.. "The APE1 redox inhibitor E3330 reduces collective cell migration of human breast cancer cells and decreases chemoinvasion and colony formation when combined with docetaxel". Chemical Biology & Drug Design 90 4 (2017): 561-571. http://dx.doi.org/10.1111/cbdd.12979.
    Published • 10.1111/cbdd.12979
  5. GUERREIRO, PATRÍCIA S.; Estácio, Sílvia G.; Antunes, Fernando; Fernandes, Ana S.; Pinheiro, Pedro F.; Costa, João G.; Castro, Matilde; et al. "Structure-based virtual screening toward the discovery of novel inhibitors of the DNA repair activity of the human apurinic/apyrimidinic endonuclease 1". Chemical Biology & Drug Design 88 6 (2016): 915-925. http://dx.doi.org/10.1111/cbdd.12826.
    Published • 10.1111/cbdd.12826
  6. Costa, João G.; Saraiva, Nuno; GUERREIRO, PATRÍCIA S.; Louro, Henriqueta; Silva, Maria J.; Miranda, Joana P.; Castro, Matilde; et al. "Ochratoxin A-induced cytotoxicity, genotoxicity and reactive oxygen species in kidney cells: An integrative approach of complementary endpoints". Food and Chemical Toxicology 87 (2016): 65-76. http://dx.doi.org/10.1016/j.fct.2015.11.018.
    Published • 10.1016/j.fct.2015.11.018
  7. Ribeiro, Isabel A. C.; Faustino, Célia M. C.; GUERREIRO, PATRÍCIA S.; Frade, Raquel F. M.; Bronze, M. Rosário; Castro, Matilde F.; Ribeiro, Maria H. L. "Development of novel sophorolipids with improved cytotoxic activity toward MDA-MB-231 breast cancer cells". Journal of Molecular Recognition 28 3 (2015): 155-165. http://dx.doi.org/10.1002/jmr.2403.
    Published • 10.1002/jmr.2403
  8. Bandarra, S.; Fernandes, A.S.; Magro, I.; GUERREIRO, PATRÍCIA S.; Pingarilho, M.; Churchwell, M.I.; Gil, O.M.; et al. "Erratum: Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells (Mutagenesis (2013) 28:6 (721-729))". Mutagenesis 29 1 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84891367154&partnerID=MN8TOARS.
    Published • 10.1093/mutage/get059
  9. Bandarra, S.; Fernandes, A. S.; Magro, I.; GUERREIRO, PATRÍCIA S.; Pingarilho, M.; Churchwell, M. I.; Gil, O. M.; et al. "Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells". Mutagenesis 28 6 (2013): 721-729. http://dx.doi.org/10.1093/mutage/get052.
    Published • 10.1093/mutage/get052
  10. GUERREIRO, PATRÍCIA S.; Fernandes, Ana Sofia; Costa, João G.; Castro, Matilde; Miranda, Joana P.; Oliveira, Nuno G.. "Differential effects of methoxyamine on doxorubicin cytotoxicity and genotoxicity in MDA-MB-231 human breast cancer cells". Mutation Research/Genetic Toxicology and Environmental Mutagenesis 757 2 (2013): 140-147. http://dx.doi.org/10.1016/j.mrgentox.2013.08.003.
    Published • 10.1016/j.mrgentox.2013.08.003
  11. Gonçalves, Sandrina; Fernandes, Ana Sofia; Oliveira, Nuno G.; Marques, Joana; Costa, Judite; Fátima Cabral, M.; Miranda, Joana; et al. "Cytotoxic effects of cadmium in mammary epithelial cells: Protective role of the macrocycle [15]pyN5". Food and Chemical Toxicology 50 6 (2012): 2180-2187. http://dx.doi.org/10.1016/j.fct.2012.04.006.
    Published • 10.1016/j.fct.2012.04.006
Thesis / Dissertation
  1. Guerreiro, Patrícia S.. "Modulation of human apurinic/apyrimidinic endonuclease 1 (APE1) functions for breast cancer therapy". PhD, Universidade de Lisboa Faculdade de Farmácia, 2016. http://hdl.handle.net/10451/26685.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2018/09 The spectraplakin Dystonin suppresses tumourigenesis through antagonizing the activity of the YAP/TAZ oncogenes DGZ 2018 - International Meeting of the German Society for Cell Biology “Concepts of Cell Organization and Dynamics”
German Society for Cell Biology (Leipzig, Germany)
2015/02 Inhibition of APE1 redox function with E3330: effects on the proliferation and migration of MDA-MB-231 breast cancer cells XLV Reunião Anual da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Lisbon, Portugal)
2014/09 Cytotoxicity, genotoxicity and ROS production by ochratoxin A in Vero cells Summer School “Biochemical Basis of Healthy Aging
Society for Free Radical Research – Europe (Spetses, Greece)
2013/07 APE1 DNA repair activity: a druggable target for the development of chemotherapeutic sensitizers 5th Post-Graduate iMed.UL Students Meeting
iMed.ULisboa Postgraduate Students Comission (Lisboa, Portugal)
2013/02 Development of APE1 inhibitors as potential sensitizing agents for chemotherapeutic drugs XLIII Reunião Anual da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Porto, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2019/02 - 2019/07 Validation of the actin-binding proteins (ABPs) interaction with P-cadherin in human breast cancer cell lines models
Supervisor
 Genetics and Biotechnology (Other)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2014/09 - 2015/01 Evaluation of the cytotoxicity of potassium bromate in mammalian cells
Co-supervisor
 Pharmaceutical Sciences (Scientific initiation)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014/02 - 2014/07 Evaluation and modulation of the cytotoxic and anti-migratory effects of docetaxel in metastatic breast carcinoma cells
Co-supervisor
 Pharmaceutical Sciences (Scientific initiation)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2012/10 - 2013/11 5th Post-Graduate iMed.UL Students Meeting, Lisbon, Portugal. This the annual reunion of the members of the iMed.ULisboa organized by the iMed.ULisboa Postgraduate Students Comission. (2013/07/18)
Meeting (Member of the Organising Committee)
 Universidade de Lisboa Faculdade de Farmácia, Portugal
2012/09 - 2013/11 4th Post-Graduate iMed.UL Students Meeting, Lisbon, Portugal. This the annual reunion of the members of the iMed.ULisboa organized by the iMed.ULisboa Postgraduate Students Comission. (2012/12/20)
Meeting (Member of the Organising Committee)
 Universidade de Lisboa Faculdade de Farmácia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2017/11/06 - 2017/11/10 This course provided a soft introduction to the use of simple analytical tools and public availalabe databases in the bioinformatic field. It was also an introduction to Next Generation Sequencing (NGS) data analysis by providing basic skills that are needed to process NGS data, such as evaluating data quality, trimming sequences, changing data formats, visualising data. Participants also learned how to address a simple transcriptomics problem, stepwise, using open source bioinformatics tools.
Workshop
 ELB17S Entry Level Bioinformatics
Instituto Gulbenkian de Ciência, Portugal
2017/10/16 - 2017/10/20 The aim of this course was to introduce the basic principles and applications of Flow Cytometry. Among other topics, it covered: fluorophores and panel design; instrument operation; controls; statistical analysis; data publication; and multiple applications. This course had both theoretical and practical sessions with national and international speakers.
Workshop
 1st FLxFlow Course - Principles and Applications of Flow Cytometry
Instituto de Medicina Molecular, Portugal

Instituto Gulbenkian de Ciência, Portugal

Fundação Champalimaud, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2011 - 2015 Teaching assistant in the curricular unit of General Chemistry Pharmaceutical Sciences (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2020 - 2021 Aging-US (1945-4589) Impact Journals, LLC
2018 - 2020 Oncotarget (1949-2553) "Impact Journals, LLC "
Distinctions

Award

2018 PRIZE FRANCISCO AUGUSTO DA FONSECA DIAS E MARIA JOSÉ MELENAS DA FONSECA DIAS FOR YOUNG INVESTIGATORS - 1st edition
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Other distinction

2015 Travel bursary to attend the 51st Congress of the European Societies of Toxicology (Eurotox 2015)
EUROTOX, Belgium