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Identification

Personal identification

Full name
Henrique Almeida

Citation names

  • Almeida, Henrique
  • Almeida H

Author identifiers

Ciência ID
0D19-14A5-3B1B
ORCID iD
0000-0002-3036-3211
Education
Degree Classification
1999
Concluded
 Medicina (Doutoramento)
Major in Ciência morfológicas
Universidade do Porto, Portugal
 Distinção e Louvor
1979 - 1984
Concluded
 Medicina (Licenciatura)
Universidade do Porto Faculdade de Medicina, Portugal
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2002/06/16 - Current Associate Professor (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
1999 - 2002 Assistant Professor (University Teacher) Universidade do Porto, Portugal
1993 - 1999 Assistant (University Teacher) Universidade do Porto Faculdade de Ciências da Nutrição e Alimentação, Portugal
1989 - 1993 Trainee Assistant (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal

Other Careers

Category
Host institution 		Employer
1989 - 1995 Interno (Médica) Ministério da Saúde, Portugal
Projects

Grant

Designation Funders
2021 - 2023/08 Endometriosis - unravelling the intricate crosstalk among endometrium and adipose tissue in the search of novel therapeutic targets
SPG2020
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 Sociedade Portuguesa de Ginecologia
Ongoing
2009 - 2011 Obesidade: o papel das melanocortinas na função do adipócito
SPEDM/ABBOT 2009
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 Sociedade Portuguesa de Endocrinologia Diabetes e Metabolismo
Concluded
2009 - 2010 Characterisation of the expression of SIRT1, SIRT6 and SIRT7 in the human corpus cavernous during ageing
Santander/UP_2009
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 Banco Santander Portugal
Concluded
2009 - 2010 Efect of resveratrol in stress-induced premature senescent human fibroblasts
Santander/UP_2009
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 Banco Santander Portugal
Concluded
2008 - 2009 Acção da Estatina na regulação da expressão dos fatores de crescimento vascular no corpo cavernoso do rato obeso. Implicações na prevenção da disfunção eréctil vasculogénica.
PrémioAlexandreMoreira_2008
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 Sociedade Portuguesa de Andrologia, Medicina Sexual e Reprodução
Concluded
2006 - 2008 Modulatory effect of follicle-stimulating hormone, FSH, in the activation of Cumullus Oophorus anti-oxidant mechanisms
Sociedade Portuguesa de Ginecologia
Principal investigator
Universidade do Porto Faculdade de Medicina, Portugal
 Sociedade Portuguesa de Ginecologia
Concluded
2006 - 2007 Functional characterization of autocrine and paracrine angiogenic mechanisms in rat corpus cavernous models
PrémioAlexandreMoreira_2006
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 Sociedade Portuguesa de Andrologia, Medicina Sexual e Reprodução
Concluded

Contract

Designation Funders
2023/03/01 - 2024/09/30 Keep Fertility at advanced maternal age: on the track of uterine senescent cells
2022.04368.PTDC
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2016/09/01 - 2020/08/31 Novel anti-obesity therapy: Melanocortins induction of beige adipocytes
PTDC/BIM-MET/2123/2014
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2017/06 - 2019/12 Código Mais - Creación de un Ecosistema Transfronterizo de Innovación en Salud
0227_CODIGOMAIS_1_E
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 Comissão Europeia
Concluded
2015/01/01 - 2018/12/31 Projeto Estrategico I3S - 04293/2013
UID/BIM/04293/2013
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2013/01/01 - 2014/12/31 Project - LA 2 - 2013-2014
PEst-C/SAU/LA0002/2013 FCOMP-01-0124-FEDER-037277
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011 - 2014 Oxidative stress modulators in human cumulus oophorus cells as determinants of oocyte fertilization and successful embryo transfer
Grant for Fertility Innovation
Principal investigator
Universidade do Porto Faculdade de Medicina, Portugal
 Merck Serono SA
Concluded
2011/01/01 - 2012/12/31 Project - LA 2 - 2011-2012
PEst-C/SAU/LA0002/2011 FCOMP-01-0124-FEDER-022718
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010 - 2011 The emerging role of melanocortins in adipocyte: from fat to facts
TANITA_2010
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 TANITA Healthy Weight Community Trust
Concluded
1995 - 1998 Adrenal mechanisms regulating arterial hypertension. Action of endothelin 1 and growth factors
PECS/PSAU/15/95 from JNICT
Research Fellow
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2023/11/07 - 2025/12/31 TRANSFIRESaúde - Impulso de la integración del ecosistema de I+i en salud euro regional para la adopción de soluciones avanzadas
0144_TRANSFIRESAUDE_1_E
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Programa Interreg España-Portugal (POCTEP) 2021-2027
Ongoing
Outputs

Publications

Book
  1. Almeida, H.; Matos, L.. Human ageing, a biological view. 2015.
    10.1002/9781118823408.ch1
  2. Almeida, H.; Matos, L.; Neves, D.. Caspase-3 and Bcl-2 expression in aging in adrenal zona reticularis after dexamethasone administration. 2007.
    10.1196/annals.1404.021
  3. Almeida, H.; Matos, L.; Ferreira, J.; Neves, D.. Age-related effects of dexamethasone administration in adrenal zona reticularis. 2006.
    10.1196/annals.1354.050
  4. Neves, D.; Santos, J.; Tomada, N.; Almeida, H.; Vendeira, P.. Aging and orchidectomy modulate expression of VEGF receptors (Flt-1 and Flk-1) on corpus cavernosum of the rat. 2006.
    10.1196/annals.1354.020
  5. Almeida, H.; Ferreira, J.; Neves, D.. Macrophages of the adrenal cortex: A morphological study of the effects of aging and dexamethasone administration. 2004.
    10.1196/annals.1297.024
Book chapter
  1. Neves, Delminda; Almeida, Henrique. "Obesity: A Bad Partner for the Elderly.". In Understanding Obesity: From its Causes to Impact on Life., 423-462. Bentham Science, 2020.
    Published
  2. Almeida, H; Neves, D. "Obesity: A Bad Partner for the Elderly". 2020.
    10.2174/9789811442636120010020
  3. Almeida, Henrique. "A difícil relação entre o envelhecimento biológico e a doença.". In Envelhecimento, Saúde e Doença, Novos desafios para a Prestação de Cuidados a Idosos, 63-91. Coisas de Ler, 2014.
    Published
  4. Almeida, Henrique; Alexandre Lobo-da-Cunha. "Complexo de Golgi e Lisossomas". In Carlos Azevedo e Cláudio Sunkel (edts.). Biologia Celular e Molecular, 301-319. Lidel, 2012.
    Published
  5. Almeida, Henrique. "Biologia do Envelhecimento – Uma introdução". In Manual de Gerontologia., 21-40. Lidel, 2012.
    Published
  6. Almeida, Henrique. "Envelhecimento – uma perspectiva biológica". In O fim da vida- Colecção «Pensamento Filosófico», 35-64. Publicações da Faculdade de Filosofia, Braga, 2007.
    Published
  7. Maria C. Magalhães; Almeida, Henrique. "Complexo de Golgi". In Biologia Celular e Molecular, Carlos Azevedo, 277-289. Lidel, 2005.
Conference abstract
  1. Cerqueira, ACN; Rodrigues, AR; Gouveia, AM; Almeida, H; Neves, D. "Metformin reduces endometrial implants and improves fertility in a mouse model of endometriosis". 2022.
  2. Cerqueira, ACN; Ribeiro, A; Rodrigues, A; Silva Carvalho, JL; Almeida, H; Neves, D. "Analysis of mi20a_1, mi145_1 and 320a_1 levels in follicular fluid of endometriosis patients. Their role as putative biomarkers for outcome of assisted reproductive technology (ART).". 2019.
  3. Rynkevic, R; Martins, P; Joyeux, L; Engels, A; Almeida, H; Fernandes, AA; Deprest, J. "MICROSTRUCTURAL VAGINAL TISSUE TRANSFORMATIONS IN VIRGIN, PREGNANT AND POSTPARTUM EWES.". 2016.
  4. Castro, JP; Reeg, S; Botelho, V; Almeida, H; Grune, T. "HSP90 impairment through oxidative cleavage leads to oxidized proteins accumulation". 2015.
    10.1016/j.freeradbiomed.2015.07.029
  5. Botelho, V; Almeida, H; Castro, JP. "Macroautophagy overexpression leads to oxidized proteins accumulation after a short time of oxidative stress". 2015.
    10.1016/j.freeradbiomed.2015.07.128
  6. Tomada, I; Almeida, H; Neves, D. "LOW-ENERGY/LOW-FAT DIET REVERSES METABOLIC SYNDROME-INDUCED CHANGES IN CAVERNOUS TISSUE OF AGED RATS". 2012.
  7. Tomada, I; Tomada, N; Almeida, H; Neves, D. "ANDROGEN DEPLETION LEADS TO UPREGULATION OF SIRT1-ENOS AXIS IN HUMAN CAVERNOUS TISSUE". 2011.
  8. Almeida, H; Ribeiro, A; Pinto, A; Gomes, F; Silva Carvalho, JL. "Complement system proteins in human follicular fluid in the course of assisted reproductive technologies". 2010.
Conference paper
  1. Neto, Ana Catarina; Adriana Raquel Rodrigues; Gouveia, Alexandra; Almeida H; Neves, Delminda. "Metformin reduces endometrial implants and improves fertility in a mouse model of endometriosis". Paper presented in 38th ESHRE Annual Meeting, Milão, 2022.
    Published • https://doi.org/10.1093/humrep/deac107.327
  2. Neto, Ana Catarina; Adriana Raquel Rodrigues; Lamas, S.; Gouveia, Alexandra; Almeida H; Neves, Delminda. "Metformin: new therapeutic approach for endometriosis-associated infertility". Paper presented in 37th ESHRE Annual Meeting, 2021.
    Published • https://doi.org/10.1093/humrep/deab130.299
  3. Timóteo-Ferreira, Filipa; Mendes, S.; Rocha N.A.; Matos, Liliana; Rodrigues, A.R.; Almeida H; Silva, E.. "Specific antioxidant effect on ovarian ageing". Paper presented in 1th Symposium on Metabolism – Ageing & Metabolism, Porto, 2019.
    In press
  4. Neto, A.C.; Ribeiro, A.; Rodrigues, A.R.; Almeida H; Neves, D.. "Analysis of mi20a_1, mi145_1 and 320a_1 levels in follicular fluid of endometriosis patients. Their role as putative biomarkers for outcome of assisted reproductive technology (ART).". Paper presented in 35th ESHRE Annual Meeting, Viena, 2019.
    Published
  5. Mendes, Sara; Filipa Timóteo; Adriana Raquel Rodrigues; Matos, Liliana; Saraiva, J.; Almeida H; Guedes-Martins, L.; Silva, Elisabete. "Maternal uterine ageing and placentation". Paper presented in 1th Symposium on Metabolism– Ageing & Metabolism, Porto, 2019.
    In press
  6. Filipa Timóteo; Mendes, Sara; Rocha, S.; Matos, L.; Adriana Raquel Rodrigues; Almeida H; Silva, Elisabete. "Improvement of age-related ovarian involution by the use of a NADPH-oxidase inhibitor". Paper presented in 14th Young European Scientist (YES) Meeting, Porto, 2019.
    Published • 10.1097/j.pbj.0000000000000054
  7. Silva, N.; Maria J. Salazar; Silva, Elisabete; Neves, Delminda; Almeida H; Gouveia, Alexandra; Adriana Raquel Rodrigues. "Beneficial effects of melanocortins on obesity-related metabolic dysfunction: a focus on the adipose tissue 10 features of premature ageing". Paper presented in 11th Symposium on Metabolism - Ageing & Metabolism, Porto, 2019.
    Published
  8. Adriana Raquel Rodrigues; Maria J. Salazar; Neves, Delminda; Almeida H; Gouveia, Alexandra. "The melanocortins against obesity-induced adipose tissue dysfunction: role in inflammation, fibrosis and stress response mechanisms.". Paper presented in 26th European Congress on Obesity (ECO 2019), Glasgow, 2019.
    Published • https://doi.org/10.1159/000497797
  9. Maria J. Salazar; Adriana Raquel Rodrigues; Neves, Delminda; Almeida H; Gouveia, Alexandra. "Characterization of a-MSH browning effect in the distinct fat depots from obese and lean mice". Paper presented in 26th European Congress on Obesity (ECO 2019), Glasgow, 2019.
    Published • https://doi.org/10.1159/000497797
  10. Maria J. Salazar; Adriana Raquel Rodrigues; Neves, Delminda; Almeida H; Magalhães, J.; Gouveia, Alexandra. "Browning effect of the melanocortins among mice different adipose tissue depots". Paper presented in 0º Simpósio de Metabolismo da Faculdade de Medicina da Universidade do Porto, Porto, 2019.
    Published
  11. Filipa Timóteo; Rocha, N.A.; Mendes, Sara; Adriana Raquel Rodrigues; Matos, L.; Almeida H; Silva, Elisabete. "Female reproductive aging: exploring the effects of antioxidant treatment". Paper presented in 13th Young European Scientist (YES) Meeting, Porto, 2018.
    Published • 10.1016/j.pbj.0000000000000032
  12. Mendes, Sara; Timóteo-Ferreira, Filipa; Adriana Raquel Rodrigues; Matos, L.; Sarava, J.; Almeida H; Guedes-Martins, L.; Silva, Elisabete. "Uterine protein oxidative modifications as a contribute to defective placentation". Paper presented in 13th Young European Scientist (YES) Meeting, Porto, 2018.
    Published • 10.1016/j.pbj.0000000000000032
  13. Adriana Raquel Rodrigues; Maria J. Salazar; Rocha-Rodrigues, Sílvia; Golçalves, I.; Cruz, Célia; Almeida H; Magalhães, J.; Gouveia, Alexandra. "Alpha-MSH induces "browning" of subcutaneous white adipose tissue in mice". Paper presented in 24th European Congress on Obesity (ECO2017), Porto, 2017.
    Published • doi:10.1159/000468958
  14. Soares, A.I.; Silveira, S.; Matos, L.; Guedes-Martins, L.; Saraiva, J.; Almeida H; Silva, Elisabete. "Maternal age and placenta redox changes". Paper presented in Unit-for-Multidisciplinary-Research-in-Biomedicine Summit, Porto, 2016.
    Published
  15. Matos, L.; Gouveia, Alexandra; Almeida H. "Involvement of unfolded protein response in cellular senescence establishment.". Paper presented in 11th International Medical Postgraduate Conference, Hradec Králové, 2014.
  16. Tomada, I.; Almeida H; Neves, Delminda. "Low-energy/low-fat diet reverses metabolic syndrome-induced changes in cavernous tissue of aged rats". Paper presented in European Society for Sexual Medicine (ESSM), Amsterdão, 2012.
    Published
  17. Fonseca, J.A.; Tomada, I.; Tomada, N.; Almeida H; Neves, Delminda. "Immunofluorescent detection of receptor Tie1 in the endothelium corpus cavernosum of aged rat and human". Paper presented in European Society for Sexual Medicine (ESSM), Amesterdão, 2012.
    Published
  18. Almeida, Henrique. "Motivação do estudante de Medicina para a investigação científica". Paper presented in Colóquio Ciência Comunicação & Democracia, 2001.
    Published
Journal article
  1. Laura López-Pingarrón; Henrique Almeida; Desirée Pereboom-Maicas; Joaquín J. García. "Pathophysiological Implications of Interstitial Cajal-like Cells (ICC-like) in Uterus: A Comparative Study with Gastrointestinal ICCs". Current Issues in Molecular Biology (2023): https://doi.org/10.3390/cimb45090476.
    10.3390/cimb45090476
  2. Laura López-Pingarrón; Henrique Almeida; Marisol Soria-Aznar; Marcos C. Reyes-Gonzales; Ana B. Rodríguez-Moratinos; Antonio Muñoz-Hoyos; Joaquín J. García. "Interstitial Cells of Cajal and Enteric Nervous System in Gastrointestinal and Neurological Pathology, Relation to Oxidative Stress". Current Issues in Molecular Biology (2023): https://doi.org/10.3390/cimb45040232.
    10.3390/cimb45040232
  3. Laura López-Pingarrón; Henrique Almeida; Marisol Soria-Aznar; Marcos C. Reyes-Gonzales; María Pilar Terrón; Joaquín J. García. "Role of Oxidative Stress on the Etiology and Pathophysiology of Amyotrophic Lateral Sclerosis (ALS) and Its Relation with the Enteric Nervous System". Current Issues in Molecular Biology (2023): https://doi.org/10.3390/cimb45040217.
    10.3390/cimb45040217
  4. Ana Catarina Neto; Mariana Santos-Pereira; Pedro Abreu-Mendes; Delminda Neves; Henrique Almeida; Francisco Cruz; Ana Charrua. "The Unmet Needs for Studying Chronic Pelvic/Visceral Pain Using Animal Models". Biomedicines (2023): https://doi.org/10.3390/biomedicines11030696.
    10.3390/biomedicines11030696
  5. Luís Montenegro; Paulo Magalhães; Adriana Costa Guerreiro; Catarina Brandão; Anabela Pinto; Henrique Almeida; Ana Martins-Bessa; Elisabete Silva. "The Contribution of the Sheep and the Goat Model to the Study of Ovarian Ageing". Biology (2023): https://doi.org/10.3390/biology12020270.
    10.3390/biology12020270
  6. Ana Filipa Martins; Ana Catarina Neto; Adriana Raquel Rodrigues; Sandra Marisa Oliveira; Cláudia Sousa-Mendes; Adelino Leite-Moreira; Alexandra Maria Gouveia; Henrique Almeida; Delminda Neves. "Metformin Prevents Endothelial Dysfunction in Endometriosis through Downregulation of ET-1 and Upregulation of eNOS". Biomedicines (2022): https://doi.org/10.3390/biomedicines10112782.
    10.3390/biomedicines10112782
  7. Felgueiras, Rodrigo; Neto, Ana C.; Rodrigues, Adriana R.; Gouveia, Alexandra M.; Almeida H; Neves, Delminda. "Anti-oxidant effect of metformin through AMPK/SIRT1/PGC-1a/SIRT3– independent GPx1 expression in the heart of mice with endometriosis". Hormone Molecular Biology and Clinical Investigation 43 4 (2022): 405-414. http://dx.doi.org/10.1515/hmbci-2022-0039.
    10.1515/hmbci-2022-0039
  8. F. Timóteo-Ferreira; D. Abreu; S. Mendes; L. Matos; A.R. Rodrigues; H. Almeida; E. Silva. "Redox imbalance in age-related ovarian dysfunction and perspectives for its prevention". Ageing Research Reviews 68 (2021): 101345-101345. https://doi.org/10.1016/j.arr.2021.101345.
    10.1016/j.arr.2021.101345
  9. "Characterization of a-MSH browning effect in diverse mice white adipose tissue depots.". Journal of molecular endocrinology (2021): https://doi.org/10.1530/JME-20-0002.
    10.1530/jme-20-0002
  10. Silva, AD; Almeida, H; da Silva, HP; Oliveira, A. "Design and evaluation of a novel approach to invisible electrocardiography (ECG) in sanitary facilities using polymeric electrodes". SCIENTIFIC REPORTS (2021): https://www.authenticus.pt/P-00T-PCV.
    10.1038/s41598-021-85697-2
  11. Mendes, S.; Timóteo-Ferreira, F.; Soares, A.I.; Rodrigues, A.R.; Silva, A.M.N.; Silveira, S.; Matos, L.; et al. "Age-related oxidative modifications to uterine albumin impair extravillous trophoblast cells function". Free Radical Biology and Medicine 152 (2020): 313-322. http://dx.doi.org/10.1016/j.freeradbiomed.2020.03.020.
    10.1016/j.freeradbiomed.2020.03.020
  12. E. Silva; H. Almeida; J. P. Castro. "(In)Fertility and Oxidative Stress: New Insights into Novel Redox Mechanisms Controlling Fundamental Reproductive Processes". Oxidative Medicine and Cellular Longevity 2020 (2020): 1-2. https://doi.org/10.1155/2020/4674896.
    10.1155/2020/4674896
  13. F. Timóteo-Ferreira; S. Mendes; N. A. Rocha; L. Matos; A. R. Rodrigues; H. Almeida; E. Silva. "Apocynin Dietary Supplementation Delays Mouse Ovarian Ageing". Oxidative Medicine and Cellular Longevity 2019 (2019): 1-11. https://doi.org/10.1155/2019/5316984.
    10.1155/2019/5316984
  14. Sara Mendes; Filipa Timóteo-Ferreira; Henrique Almeida; Elisabete Silva. "New Insights into the Process of Placentation and the Role of Oxidative Uterine Microenvironment". Oxidative Medicine and Cellular Longevity 2019 (2019): 1-18. https://doi.org/10.1155/2019/9174521.
    10.1155/2019/9174521
  15. Rynkevic, Rita; Martins, Pedro; Andre, Antonio; Parente, Marco; Mascarenhas, Teresa; Almeida H; Fernandes, Antonio A.. "The effect of consecutive pregnancies on the ovine pelvic soft tissues: Link between biomechanical and histological components". Annals of Anatomy - Anatomischer Anzeiger 222 (2019): 166-172. http://dx.doi.org/10.1016/j.aanat.2018.12.002.
    10.1016/j.aanat.2018.12.002
  16. Castro, JP; Fernando, R; Reeg, S; Meinl, W; Almeida, H; Grune, T. "Non-enzymatic cleavage of Hsp90 by oxidative stress leads to actin aggregate formation: A novel gain-of-function mechanism". REDOX BIOLOGY (2019): https://www.authenticus.pt/P-00Q-EN0.
    10.1016/j.redox.2019.101108
  17. "Peripherally administered melanocortins induce mice fat browning and prevent obesity.". International journal of obesity (2005) (2018): https://doi.org/10.1038/s41366-018-0155-5.
    10.1038/s41366-018-0155-5
  18. Rocha, B.; Rodrigues, A. R.; Tomada, I.; Martins, M. J.; Guimarães, J. T.; Gouveia, A. M.; Almeida H; Neves, D.. "Energy restriction, exercise and atorvastatin treatment improve endothelial dysfunction and inhibit miRNA-155 in the erectile tissue of the aged rat.". Nutrition & Metabolism 15 1 (2018): http://dx.doi.org/10.1186/s12986-018-0265-z.
    10.1186/s12986-018-0265-z
  19. Matos, L.; Gouveia, A.M.; Almeida, H.. "Resveratrol Attenuates Copper-Induced Senescence by Improving Cellular Proteostasis". Oxidative Medicine and Cellular Longevity 2017 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85013485217&partnerID=MN8TOARS.
    10.1155/2017/3793817
  20. Freitas, C.; Neto, A.C.; Matos, L.; Silva, E.; Ribeiro, Â.; Silva-Carvalho, J.L.; Almeida, H.. "Follicular Fluid redox involvement for ovarian follicle growth". Journal of Ovarian Research 10 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85023164526&partnerID=MN8TOARS.
    10.1186/s13048-017-0342-3
  21. Ribeiro, A.; Freitas, C.; Matos, L.; Gouveia, A.; Gomes, F.; Silva Carvalho, J.L.; Almeida, H.. "Age-related expression of TGF beta family receptors in human cumulus oophorus cells". Journal of Assisted Reproduction and Genetics 34 9 (2017): 1121-1129. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018389055&partnerID=MN8TOARS.
    10.1007/s10815-017-0930-6
  22. Liliana Matos; Alexandra Monteiro Gouveia; Henrique Almeida. "Erratum to “Resveratrol Attenuates Copper-Induced Senescence by Improving Cellular Proteostasis”". Oxidative Medicine and Cellular Longevity 2017 (2017): 1-10. https://doi.org/10.1155/2017/9172085.
    10.1155/2017/9172085
  23. Rynkevic, R.; Martins, P.; Hympanova, L.; Almeida, H.; Fernandes, A.A.; Deprest, J.. "Biomechanical and morphological properties of the multiparous ovine vagina and effect of subsequent pregnancy". Journal of Biomechanics 57 (2017): 94-102. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018671429&partnerID=MN8TOARS.
    10.1016/j.jbiomech.2017.03.023
  24. Rodrigues, A.R.; Sousa, D.; Almeida, H.; Gouveia, A.M.. "Cell surface targeting of the Melanocortin 5 Receptor (MC5R) requires serine-rich terminal motifs". Biochimica et Biophysica Acta - Molecular Cell Research 1864 7 (2017): 1217-1226. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018609533&partnerID=MN8TOARS.
    10.1016/j.bbamcr.2017.04.004
  25. Sousa-Pinto, B.; Gonçalves, L.; Rodrigues, A.R.; Tomada, I.; Almeida, H.; Neves, D.; Gouveia, A.M.. "Characterization of TGF-ß expression and signaling profile in the adipose tissue of rats fed with high-fat and energy-restricted diets". Journal of Nutritional Biochemistry 38 (2016): 107-115. http://www.scopus.com/inward/record.url?eid=2-s2.0-84991503722&partnerID=MN8TOARS.
    10.1016/j.jnutbio.2016.07.017
  26. Silva, E.; Soares, A.I.; Costa, F.; Castro, J.P.; Matos, L.; Almeida, H.. "Antioxidant supplementation modulates age-related placental bed morphology and reproductive outcome in mice". Biology of Reproduction 93 3 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84943236013&partnerID=MN8TOARS.
    10.1095/biolreprod.114.127746
  27. Matos, L.; Gouveia, A.M.; Almeida, H.. "ER stress response in human cellular models of senescence". Journals of Gerontology - Series A Biological Sciences and Medical Sciences 70 8 (2015): 924-935. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940896820&partnerID=MN8TOARS.
    10.1093/gerona/glu129
  28. Guedes-Martins, L.; Silva, E.; Gaio, A.R.; Saraiva, J.; Soares, A.I.; Afonso, J.; Macedo, F.; Almeida, H.. "Fetal-maternal interface impedance parallels local NADPH oxidase related superoxide production". Redox Biology 5 (2015): 114-123. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928229447&partnerID=MN8TOARS.
    10.1016/j.redox.2015.04.007
  29. Guedes-Martins, L.; Gaio, A.R.; Saraiva, J.; Cunha, A.; Macedo, F.; Almeida, H.. "Uterine artery impedance during the first eight postpartum weeks". Scientific Reports 5 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84929998709&partnerID=MN8TOARS.
    10.1038/srep08786
  30. Guedes-Martins, L.; Gaio, R.; Saraiva, J.; Cerdeira, S.; Matos, L.; Silva, E.; Macedo, F.; Almeida, H.. "Reference Ranges for uterine artery pulsatility index during the menstrual cycle: A cross-sectional study". PLoS ONE 10 3 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84924289939&partnerID=MN8TOARS.
    10.1371/journal.pone.0119103
  31. Guedes-Martins, L.; Saraiva, J.P.; Gaio, A.R.; Reynolds, A.; Macedo, F.; Almeida, H.. "Uterine artery Doppler in the management of early pregnancy loss: A prospective, longitudinal study". BMC Pregnancy and Childbirth 15 1 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84924167361&partnerID=MN8TOARS.
    10.1186/s12884-015-0464-9
  32. Guedes-Martins, L.; Carvalho, M.; Silva, C.; Cunha, A.; Saraiva, J.; Macedo, F.; Almeida, H.; Rita Gaio, A.. "Relationship between body mass index and mean arterial pressure in normotensive and chronic hypertensive pregnant women: A prospective, longitudinal study". BMC Pregnancy and Childbirth 15 1 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84945962912&partnerID=MN8TOARS.
    10.1186/s12884-015-0711-0
  33. Tomada, I.; Negrão, R.; Almeida, H.; Neves, D.. "Long-term high-fat consumption leads to downregulation of Akt phosphorylation of eNOS at Ser1177 and upregulation of Sirtuin-1 expression in rat cavernous tissue". Age 36 2 (2014): 597-611. http://www.scopus.com/inward/record.url?eid=2-s2.0-84898662208&partnerID=MN8TOARS.
    10.1007/s11357-013-9591-2
  34. Guedes-Martins, L.; Graça, H.; Saraiva, J.P.; Guedes, L.; Gaio, R.; Cerdeira, A.S.; Macedo, F.; Almeida, H.. "The effects of spinal anaesthesia for elective caesarean section on uterine and umbilical arterial pulsatility indexes in normotensive and chronic hypertensive pregnant women: A prospective, longitudinal study". BMC Pregnancy and Childbirth 14 1 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84965180565&partnerID=MN8TOARS.
    10.1186/1471-2393-14-291
  35. Guedes-Martins, L.; Cunha, A.; Saraiva, J.; Gaio, R.; Macedo, F.; Almeida, H.. "Internal iliac and uterine arteries Doppler ultrasound in the assessment of normotensive and chronic hypertensive pregnant women.". Scientific reports 4 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84906099643&partnerID=MN8TOARS.
    10.1038/srep03785
  36. Guedes-Martins, L.; Cunha, A.; Saraiva, J.; Rita-Gaio, A.; Cerdeira, A.S.; Macedo, F.; Almeida, H.. "Foetal aortic flow velocity waveforms in healthy and hypertensive pregnant women". Cardiovascular Ultrasound 12 1 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84896708410&partnerID=MN8TOARS.
    10.1186/1476-7120-12-1
  37. Guedes-Martins, L.; Saraiva, J.; Felgueiras, Ó.; Carvalho, M.; Cerdeira, A.; Macedo, F.; Gaio, R.; Almeida, H.. "Uterine artery impedance during puerperium in normotensive and chronic hypertensive pregnant women". Archives of Gynecology and Obstetrics (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84916607971&partnerID=MN8TOARS.
    10.1007/s00404-014-3560-6
  38. Rodrigues, A.R.; Almeida, H.; Gouveia, A.M.. "Intracellular signaling mechanisms of the melanocortin receptors: current state of the art". Cellular and Molecular Life Sciences (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84917707029&partnerID=MN8TOARS.
    10.1007/s00018-014-1800-3
  39. Guedes-Martins, L.; Saraiva, J.; Gaio, R.; Macedo, F.; Almeida, H.. "Uterine artery impedance at very early clinical pregnancy". Prenatal Diagnosis 34 8 (2014): 719-725. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905400195&partnerID=MN8TOARS.
    10.1002/pd.4325
  40. Tomada, I.; Fernandes, D.; Guimarães, J.T.; Almeida, H.; Neves, D.. "Energy restriction ameliorates metabolic syndrome-induced cavernous tissue structural modifications in aged rats". Age 35 5 (2013): 1721-1739. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892580650&partnerID=MN8TOARS.
    10.1007/s11357-012-9473-z
  41. Rodrigues, A.R.; Sousa, D.; Almeida, H.; Gouveia, A.M.. "Structural determinants regulating cell surface targeting of melanocortin receptors". Journal of Molecular Endocrinology 51 2 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84884620346&partnerID=MN8TOARS.
    10.1530/JME-13-0055
  42. Rodrigues, A.R.; Almeida, H.; Gouveia, A.M.. "a-MSH signalling via melanocortin 5 receptor promotes lipolysis and impairs re-esterification in adipocytes". Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1831 7 (2013): 1267-1275. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877661657&partnerID=MN8TOARS.
    10.1016/j.bbalip.2013.04.008
  43. Castro, J.P.; Jung, T.; Grune, T.; Almeida, H.. "Actin carbonylation: From cell dysfunction to organism disorder". Journal of Proteomics 92 (2013): 171-180. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886953660&partnerID=MN8TOARS.
    10.1016/j.jprot.2013.05.006
  44. Guedes-Martins, L.; Matos, L.; Soares, A.; Silva, E.; Almeida, H.. "AGEs, contributors to placental bed vascular changes leading to preeclampsia". Free Radical Research 47 S1 (2013): 70-80. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881228672&partnerID=MN8TOARS.
    10.3109/10715762.2013.815347
  45. Tomada, I.; Tomada, N.; Almeida, H.; Neves, D.. "Androgen depletion in humans leads to cavernous tissue reorganization and upregulation of Sirt1-eNOS axis". Age 35 1 (2013): 35-47. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872595357&partnerID=MN8TOARS.
    10.1007/s11357-011-9328-z
  46. Castro, J.P.; Ott, C.; Jung, T.; Grune, T.; Almeida, H.. "Carbonylation of the cytoskeletal protein actin leads to aggregate formation". Free Radical Biology and Medicine 53 4 (2012): 916-925. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864448289&partnerID=MN8TOARS.
    10.1016/j.freeradbiomed.2012.06.005
  47. Matos, L.; Gouveia, A.; Almeida, H.. "Copper ability to induce premature senescence in human fibroblasts". Age 34 4 (2012): 783-794. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866491060&partnerID=MN8TOARS.
    10.1007/s11357-011-9276-7
  48. Tomada, I.; Tomada, N.; Almeida, H.; Neves, D.. "Energy restriction and exercise modulate angiopoietins and vascular endothelial growth factor expression in the cavernous tissue of high-fat diet-fed rats". Asian Journal of Andrology 14 4 (2012): 635-642. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863672272&partnerID=MN8TOARS.
    10.1038/aja.2011.131
  49. Rodrigues, A.R.; Almeida, H.; Gouveia, A.M.. "Melanocortin 5 receptor signaling and internalization: Role of MAPK/ERK pathway and ß-arrestins 1/2". Molecular and Cellular Endocrinology 361 1-2 (2012): 69-79. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864359242&partnerID=MN8TOARS.
    10.1016/j.mce.2012.03.011
  50. Tomada, I.; Fernandes, D.; Tomada, N.; Almeida, H.; Neves, D.. "Cavernous vessels smooth muscle layer thickness correlates with myocardium collagen deposition in high-fat fed rats". Microscopy and Microanalysis 18 SUPPL.5 (2012): 19-20. http://www.scopus.com/inward/record.url?eid=2-s2.0-84894657559&partnerID=MN8TOARS.
    10.1017/S1431927612012755
  51. Fernandes, D.; Tomada, I.; Almeida, H.; Neves, D.. "Chronic ingestion of high-fat diet and energy restriction modulates expression of VEGF and VEGFR2 in aged rat myocardium". Microscopy and Microanalysis 18 SUPPL.5 (2012): 7-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-84894660732&partnerID=MN8TOARS.
    10.1017/S143192761201269X
  52. Adriana Raquel Rodrigues; Almeida, Henrique; Gouveia, Alexandra. "Obesidade: O Papel das Melanocortinas na regulacao da Homeostasia Energetica". Rev. Port. Endoc. Diab Metab 6 1 (2011): 76-86.
    Published
  53. Almeida, H.. "The field of microscopy research. Introduction.". Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 16 6 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-79952476649&partnerID=MN8TOARS.
  54. Almeida, H.. "Microscopy and Microanalysis: Introduction". Microscopy and Microanalysis 16 6 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-79451470917&partnerID=MN8TOARS.
    10.1017/S1431927610094237
  55. Cordeiro, A.L.; Figueiredo, A.; Tomada, I.; De Almeida, H.; Neves, D.. "Characterization of the expression of Ang1, Ang2, and Tie2 in the corpus cavernosum of the rat during aging". Microscopy and Microanalysis 16 6 (2010): 699-709. http://www.scopus.com/inward/record.url?eid=2-s2.0-79451474776&partnerID=MN8TOARS.
    10.1017/S1431927610094006
  56. Neves, D.R.; Tomada, I.M.; Assunção, M.M.; Marques, F.A.; Almeida, H.M.; Andrade, J.P.. "Effects of chronic red wine consumption on the expression of vascular endothelial growth factor, angiopoietin 1, angiopoietin 2, and its receptors in rat erectile tissue". Journal of Food Science 75 3 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77953905237&partnerID=MN8TOARS.
    10.1111/j.1750-3841.2010.01527.x
  57. Rodrigues, A.R.; Pignatelli, D.; Almeida, H.; Gouveia, A.M.. "Melanocortin 5 receptor activates ERK1/2 through a PI3K-regulated signaling mechanism". Molecular and Cellular Endocrinology 303 1-2 (2009): 74-81. http://www.scopus.com/inward/record.url?eid=2-s2.0-62949102680&partnerID=MN8TOARS.
    10.1016/j.mce.2009.01.014
  58. Matos, L.; Stevenson, D.; Gomes, F.; Silva-carvalho, J.L.; Almeida, H.. "Superoxide dismutase expression in human cumulus oophorus cells". Molecular Human Reproduction 15 7 (2009): 411-419. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649233795&partnerID=MN8TOARS.
    10.1093/molehr/gap034
  59. Tomada, I; Tomada, N; Almeida, H; Vendeira, P; Neves, D. "Morphometric and molecular study of corpus cavernosum of the rat after longterm high-fat diet intake". Microscopy and Microanalysis - Microsc Microanal (2009): https://www.authenticus.pt/P-00H-H7T.
    10.1017/s1431927609990560
  60. Neves, D.; Assunção, M.; Marques, F.; Andrade, J.P.; Almeida, H.. "Does regular consumption of green tea influence expression of vascular endothelial growth factor and its receptor in aged rat erectile tissue? Possible implications for vasculogenic erectile dysfunction progression". Age 30 4 (2008): 217-228. http://www.scopus.com/inward/record.url?eid=2-s2.0-56749158937&partnerID=MN8TOARS.
    10.1007/s11357-008-9051-6
  61. Martins, P.; Schmitt, F.; Almeida, H.; Frazão, J.M.. "Evaluation of parathyroid gland angiogenesis in chronic kidney disease associated with secondary hyperparathyroidism". Nephrology Dialysis Transplantation 23 9 (2008): 2889-2894. http://www.scopus.com/inward/record.url?eid=2-s2.0-58549085984&partnerID=MN8TOARS.
    10.1093/ndt/gfn150
  62. Matos, L.; Stevenson, D.; Gomes, F.; Silva-Carvalho, J.L.; Almeida, H.. "Superoxide dismutase detection in human cumulus oophorus cells". Microscopy and Microanalysis 14 SUPPL. 3 (2008): 99-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-53349107505&partnerID=MN8TOARS.
    10.1017/S1431927608089514
  63. Cordeiro, A.L.; Figueiredo, A.; Godinho, F.; Martins, I.; Vendeira, P.; Almeida, H.; Neves, D.. "Ultrastructural characterization of corpus cavernosum of ageing, orchidectomy and diabetes rat experimental models". Microscopy and Microanalysis 14 SUPPL. 3 (2008): 97-98. http://www.scopus.com/inward/record.url?eid=2-s2.0-53349146503&partnerID=MN8TOARS.
    10.1017/S1431927608089502
  64. Rodrigues, A.R.; Gouveia, A.M.; Ferreira, J.G.; Almeida, H.. "ACTH induces ERK 1/2 activation in rat adrenal primary cultures". Microscopy and Microanalysis 14 SUPPL. 3 (2008): 101-102. http://www.scopus.com/inward/record.url?eid=2-s2.0-53349175612&partnerID=MN8TOARS.
    10.1017/S1431927608089526
  65. Almeida, Henrique. "Células estaminais: dúvidas de hoje e esperanças de sempre". Brotéria 164 4 (2007): 319-334.
    Published
  66. Almeida, Henrique. "O metabolismo nos caminhos do envelhecimento". Revista Portuguesa de Endocrinologia, Diabetes e Metabolismo 2 2 (2007): 39-46.
    Published
  67. N Tomada; J Santos; Almeida, Henrique; Neves, Delminda; P Vendeira. "Distribuição do território endotelial e da expressão de VEGF em modelo experimental de pénis de rato. Efeitos da orquidectomia bilateral e do envelhecimento". Acta Urológica 23 (2006): 45-52.
    Published
  68. Santos, J.; Neves, D.; Tomada, N.; Almeida, H.; Vendeira, P.. "Expression of vascular endothelial growth factor (VEGF) and VEGF-specific receptors (Flt-1 and Flk-1) on rat corpus cavernosum. Influence of aging and orchidectomy | Expressão do VEGF e dos receptores Flt-1 e Flk-1 no corpo cavernoso do rato. Acção do envelhecimento e da orquidectomia". Revista Internacional de Andrologia 3 3 (2005): 120-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949819506&partnerID=MN8TOARS.
    10.1016/S1698-031X(05)73258-1
  69. J Santos; Delminda Neves; N Tomada; Almeida, Henrique; P Vendeira. "Expressão do VEGF e dos receptors Flt-1 e Flk-1 no corpo cavernoso do rato. Acção do envelhecimento e da orquidectomia.". Revista Internacional de Andrologia (Espanha) 3 3 (2005): 120-127.
    Published
  70. Almeida, H.. "Is the US benefiting from non-US scientists? [2]". Nature Cell Biology 2 7 (2000): http://www.scopus.com/inward/record.url?eid=2-s2.0-0033775680&partnerID=MN8TOARS.
    10.1038/35017122
  71. Almeida H. "Hormonas do córtex supra-renal durante o envelhecimento.". Revista Portuguesa de Medicina Geriátrica – Geriatria 13 (2000): 11-22.
    Published
  72. Silva, P.T.; De Almeida, H.M.N.; Príncipe, F.; Pereira-Leite, L.. "Non-Hodgkin lymphoma during pregnancy". European Journal of Obstetrics Gynecology and Reproductive Biology 77 2 (1998): 249-251. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032053642&partnerID=MN8TOARS.
    10.1016/S0301-2115(97)00261-3
  73. Almeida, H.; Magalhães, M.C.; Magalhães, M.M.. "Age-related effects on the zona glomerulosa cells of the rat adrenal cortex". Aging Male 1 4 (1998): 254-263. http://www.scopus.com/inward/record.url?eid=2-s2.0-25844464152&partnerID=MN8TOARS.
  74. Almeida, H.; Magalhaes, M.C.; Magalhaes, M.M.. "Age-related changes in lipid peroxidation products in rat adrenal gland". Age 21 3 (1998): 119-121. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032456348&partnerID=MN8TOARS.
    10.1007/s11357-998-0018-4
  75. De Almeida, H.; Magalhães, M.C.; Magalhães, M.M.. "Age-related changes in the inner zone of the adrenal cortex of the rat - A morphologic and biochemical study". Mechanisms of Ageing and Development 105 1-2 (1998): 1-18. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345367931&partnerID=MN8TOARS.
    10.1016/S0047-6374(98)00099-2
  76. da Silva, P.T.; de Almeida, H.; Braganca, E.; Patricio, B.; Leite, L.P.. "Pregnancy and travel | Gravidez e viagens". Arquivos de Medicina 12 1 (1998): 34-37. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031919256&partnerID=MN8TOARS.
  77. Pignatelli, D.; Pinto, P.; Almeida, H.; Magalhães, M.M.; Magalhães, M.C.; Ho, M.M.; Vinson, G.P.. "The development of the adrenal cortex in the rat. An immunohistochemical study". Endocrine Research 21 1-2 (1995): 129-136. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029052274&partnerID=MN8TOARS.
    10.3109/07435809509030429
  78. Almeida, H.; Magalhães, M.; Magalhães, M.C.. "Nucleolar alterations induced by 4-aminopyrazolo(3,4-d)pyrimidine in adrenal cortex and liver cells of rat". Cell and Tissue Research 248 1 (1987): 231-234. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023137364&partnerID=MN8TOARS.
    10.1007/BF01239986
  79. Almeida, H.; Magalhães, M.M.; Serra, T.A.M.; Hipólito-Reis, C.; Magalhães, M.C.. "Ultrastructural and biochemical alterations produced in rat adrenal cortex by 4-aminopyrazolopyrimidine". Journal of Ultrastructure Research and Molecular Structure Research 97 1-3 (1986): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-0022952504&partnerID=MN8TOARS.
    10.1016/S0889-1605(86)80002-7
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2010/06/27 Complement system proteins in human follicular fluid in the course of Assisted Reproductive Technologies Selected oral communication session. Clinical ART2. ESHRE Annual Meeting
(Roma, Italy)
2010/05/28 Stress oxidativo - um condicionante da maturação ovocitária 167ª Reunião da Sociedade Portuguesa de Ginecologia
(Évora, Portugal)
2009 Follicular cells and fluids to access oocyte quality Infertility in Portugal: Epidemiology, Laws & Research. Symposium of the Portuguese Society of Reproductive Medicine at the 13th World Congress of The International Academy of Human Reproduction
(Veneza, Italy)
2009 The oocyte environment in the evaluation of its quality Symposium of the «9ª Reunião (9º Taller General) da Rede Latino-Americana de Reprodução Assistida, Red-Lara»
(Cancun, Mexico)
2008 Biologia Celular do Envelhecimento biológico XIV Curso Pós-Graduado de Endocrinologia, Diabetes e Metabolismo
(Porto, Portugal)
2008 Intake of nutritionally defined diets crosstalk with ageing in endothelial dysfunction LINK-AGE Satellite Working Research Group B Meeting. NH Conference Centre Leeuwenhorst
(Noordwijkerhout, Netherlands)
2007 Células estaminais: dúvidas de hoje e esperanças de sempre Conferência na Universidade Católica
(Funchal, Portugal)
2007 Envelhecimento - Algumas teorias e factos biológicos Jornadas de Diabetes, Endocrinologia e Metabolismo
2006 Envelhecimento, uma perspectiva biológica. II Jornadas de Bioética da Universidade Católica
(Braga, Portugal)
2006 Envelhecimento, uma perspectiva biológica II Jornadas de Bioética da Universidade Católica
(Funchal, Portugal)
2003 Stress in animals – Hypothalamus, pituitary axis (HPA) overview Cell Adaptive Mechanisms. Ongoing work and future perspectives. 2nd Workshop
(Vairão, Portugal)
2003 Apoptosis in the aged adrenal cortex Cell Adaptive Mechanisms. Ongoing work and future perspectives. 2nd Workshop
(Vairão, Portugal)
2001 Motivação do estudante de Medicina para a investigação científica Colóquio Ciência, Comunicação & Democracia
Casa-Museu Abel Salazar, Porto (Porto, Portugal)
1997 Age-related changes in rat adrenal cortex - morphologic and biochemical studies 3rd BioMed Conference on Molecular Gerontology
Comune di Numana, Italy, and Aarhus University, Denmark
1991 Cytoplasmic changes of zona reticularis cells of the adrenal cortex of the rat with aging Franco-Ibérico de Microscopia Electrónica
Universitat de Barcelona (Barcelona, Spain)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023 - Current A senolytic approach to delay ovarian ageing
Co-supervisor of Natália Rigos Felix
 Programa Doutoral em Biologia Molecular e Celular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 - Current Reproductive Aging in Dog and Cat: a clinical and histological study
Supervisor of Luís Miguel Fonte Montenegro
Universidade de Trás-os-Montes e Alto Douro Centro de Ciência Animal e Veterinária, Portugal
2020 - Current Understanding the role of Obesity and Adipose Tissue in the pathogenesis of COVID-19
Co-supervisor of Maria João Bastos Salazar
 Programa Doutoral em Biomedicina (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2017 - Current Role of metformin in the control of oxidative stress and infertility in endometriosis
Co-supervisor of Ana Catarina S. Neto Cerqueira
 Programa Doutoral em Biomedicina (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2015 - Current Anti-neutrophil cytoplasmic antibodies associated vasculitis. Towards Personalized Medicine»
Co-supervisor of Marta Isabel Rodrigues Casal Moura
 Programa Doutoral em Medicina e Oncologia Molecular (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2011 - Current Identificação de biomarcadores em células do cumulus oophorus humanas e importância em Procriação Medicamente Assistida. Modulação de vias transductivas com a idade
Supervisor of Maria Ângela Esteves Ribeiro
 Programa Doutoral em Biomedicina (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2008 - Current Estudo clínico e molecular de factores de prognóstico em Procriação Medicamente Assistida
Supervisor of Cláudia Vivina Marques de Freitas
 Programa Doutoral em Medicina (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2020 - 2022 Female fertility decline: addressing the role of cellular senescence
Supervisor of Adriana Costa Guerreiro
 Mestrado em Biotecnologia para as Ciências da Saúde (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2017 - 2019 Female fertility decline: exploring the role of antioxidants in delaying ovarian ageing
Co-supervisor of Filipa Timoteo Ferreira
 Mestrado em Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2016 - 2018 Differential Expression Profiling in an Immortalized Human Granulosa Cell Line (GC1a)
Supervisor of Mafalda Costa Pardalejo
 Mestrado em Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2013 - 2015 O papel da Melanocortina ALFA-MSH - Na transdiferenciação de adipocitos brancos em beges.
Co-supervisor of Maria João Bastos Salazar
 Mestrado em Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2009 - 2015 Actin cytoskeleton carbonylation in Human T-lymphocytes: a role in cellular senescence
Supervisor of José Pedro Quinta Araújo Castro
 Programa Doutoral em Biomedicina (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2008 - 2015 Metal-induced oxidative stress in human fibroblasts: a role in cellular ageing
Supervisor of Liliana Raquel Casais de Matos
 Programa Doutoral Metabolismo - Clínica e Experimentação (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2007 - 2015 Estados hipertensivos da gravidez: alterações da fluxometria Doppler materna moduladora da activação de apoptose no leito placentar
Supervisor of Luis Guedes Martins
 Programa Doutoral em Medicina e Oncologia Molecular (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2012 - 2014 Hormona anti-muleriana e oocyte secreted factors no líquido folicular humano na avaliação de distúrbios da infertilidade
Co-supervisor of Ana Catarina S. Neto Cerqueira
 Mestrado em Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2012 - 2014 Modulação morfofuncional da linha GC1apor fatores ovocitários.
Supervisor of Sandra de Almeida Reis
 Mestrado em Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2011 - 2014 Suplementação alimentar com antioxidantes e o sucesso reprodutivo em fêmeas de murganho envelhecidas
Co-supervisor of Ana Isabel Cardoso Soares
 Mestrado em Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2007 - 2013 Molecular mechanisms of the melanocortin receptors signal transduction in adrenal gland cells
Co-supervisor of Adriana Raquel Campos Rodrigues
 Programa Doutoral em Biomedicina (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2007 - 2013 Molecular dissection of angiogenic mechanisms in corpus cavernosum of rat experimental model. Ageing and obesity crosstalk for endothelial dysfunction progression
Co-supervisor of Inês Margarida Araújo Soares Costa Tomada Marques
 Programa Doutoral - Metabolismo - Clínica e Experimentação (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2007 - 2009 Evidência de receptores de OSFs em células do cumulus oophorus humanas.
Supervisor of Maria Ângela Esteves Ribeiro
 Mestrado em Biologia (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2006 - 2008 Carbonilação de proteínas linfocitárias humanas.
Supervisor of José Pedro Quinta Araújo Castro
 Mestrado em Microbiologia (Master)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2006 - 2008 Dismútases do anião superóxido nas células do cumulus oophorus humanas.
Supervisor of Liliana Raquel Casais de Matos
 Mestrado em Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2006 - 2008 O condicionamento do abortamento eugénico pelo diagnóstico pré-natal na Região Autónoma da Madeira.
Supervisor of Natacha Luísa de Brito Marques Silva
 Mestrado em Bioética (Master)
Universidade Catolica Portuguesa Faculdade de Filosofia e Ciencias Sociais, Portugal
2003 - 2005 Sindromas de Gilbert e Crigler-Najjar: análise mutacional e relação genótipo/fenótipo
Supervisor of Elísio Manuel Sousa Costa
 Mestrado Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018 - Current Programa Doutoral (Terceiro Ciclo de Estudos) em Medicina e Oncologia Molecular. Direcção. (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2009 - Current Mestrado (Segundo Ciclo de Estudos) em Medicina e Oncologia Molecular. Direcção. (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2016 - 2018 Comissão de Avaliação Externa (CAE) de Ciclos de Estudos na área das Ciências Dentárias. Presidente.
Other

Journal scientific committee

Journal title (ISSN) Publisher
2009 - Current Microscopy and Microanalysis (1435-8115) Cambridge University Press
Distinctions

Award

2022 Melhor Comunicação Oral - 8º Congresso Português SPMR
Sociedade Portuguesa de Medicina da Reprodução, Portugal
2018 Melhor comunicação Oral - 10th Symposium Metabolism
Universidade do Porto Faculdade de Medicina, Portugal
2014 Best Basic Research - 66th Annual Meeting of SPEDM
Sociedade Portuguesa de Endocrinologia Diabetes e Metabolismo, Portugal
2012 Prémio Crioestaminal
2011 Grant For Fertility Innovation
Merck Serono SA, Switzerland
2010 Prémio de Investigação Basica do X Congresso Português de Endocrinologia
Sociedade Portuguesa de Endocrinologia Diabetes e Metabolismo, Portugal
2009 Prémio Fresenius
Fresenius Medical Care Portugal, Portugal
2005 Melhor Poster - XII Congresso Nacional
Asociación Española de Andrología Medicina Sexual y Reproductiva, Spain
2004 Melhor Poster - 39ª Reunião SPMicros
Sociedade Portuguesa de Microscopia (SPMicros)., Portugal
2004 Investigação Científica na Pré-Graduação - Ciências da Saúde - 1º Prémio
Universidade do Porto, Portugal

Other distinction

1977 Participação na International Youth Science Fortnight - London
Fundação Calouste Gulbenkian, Portugal