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Bruno Daniel Costa Gomes has an extensive educational background, starting with a Bachelor’s degree in Biology from Universidade Lusófona de Humanidades e Tecnologias, Portugal (2002-2008). He then pursued a Doctorate in Life Sciences with specialization in Genetics, Human Toxicology and Oncology from Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal (2010-2016), where he graduated Summa Cum Laude. His thesis was titled “microRNA involvement in breast cancer susceptibility and progression”. Bruno has completed several postgraduate courses and other training, including Laboratory Animal Sciences (Felasa B), Clinical Trials, a hands-on course in Bioinformatics tools in Clinical Proteomics Data Analysis, and the 5th EACR-OECI Joint Training Course on Molecular Pathology Approach. Bruno has held several research positions, including roles at the Universidade Nova de Lisboa Faculdade de Ciências Médicas (NMS-UNL), Instituto de Medicina Molecular (IMM), and Instituto Nacional de Saúde Doutor Ricardo Jorge IP (INSA). He is also heavily involved in teaching, currently serving as an Assistant Professor at Universidade Lusófona de Humanidades e Tecnologias Escola de Psicologia e Ciências da Vida, Portugal, and as an Invited Assistant Professor at Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal. Bruno works in the area of Medical and Health Sciences with emphasis on Basic Medicine. In his professional activities he has interacted with 154 collaborators and co-authors of scientific papers. Bruno has published 24 peer-reviewed articles and 4 book chapters, supervised 3 MSc dissertations and co-supervised 3.
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Identification

Personal identification

Full name
Bruno Daniel Costa Gomes

Citation names

  • Gomes, BC
  • Bruno Costa Gomes

Author identifiers

Ciência ID
1110-883F-9181
ORCID iD
0000-0002-5632-1095

Email addresses

  • bruno.gomes@nms.unl.pt (Professional)
  • bruno.gomes@ulusofona.pt (Professional)

Addresses

  • Rua Câmara Pestana, 6 (Edifício CEDOC II, Lab 2.12), 1150-082, Lisboa, Lisboa, Portugal (Professional)
  • Campo Grande, 376, 1749-024, Lisboa, Lisboa, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Intermediate (B1) Advanced (C1) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Education
Degree Classification
2017 - 2017
Concluded
 Laboratory Animal Sciences (Felasa B) (Pós-Graduação)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2017 - 2017
Concluded
 Clinical Trials (Pós-Graduação)
Universidade de Lisboa Faculdade de Medicina, Portugal
2010/08 - 2016/12
Concluded
 Ciências da Vida (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
"microRNA involvement in breast cancer susceptibility and progression" (THESIS/DISSERTATION)
 Summa Cum Laude
2016 - 2016
Concluded
 Hands-on Course - Bioinformatics tools in Clinical Proteomics Data Analysis (Outros)
Universidade de Lisboa Faculdade de Ciências, Portugal
2015 - 2015
Concluded
 5th EACR-OECI Joint Training Course on Molecular Pathology Approach (Outros)
European Association For Cancer Research, United Kingdom
2002/10/01 - 2008/07
Concluded
 Biology (Licenciatura)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
 17
2008 - 2008
Concluded
 COURSE STATISTICAL ANALYSIS USING SPSS IN BIOMEDICINE (Outros)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Affiliation

Science

Category
Host institution 		Employer
2022/09/01 - Current Researcher (Research) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Universidade Nova de Lisboa Centro de Toxicogenómica e Saúde Humana, Portugal
2019/04/01 - 2022/02/28 Postdoc (Research) Instituto de Medicina Molecular, Portugal
Universidade Nova de Lisboa Centro de Toxicogenómica e Saúde Humana, Portugal
2018/04/15 - 2019/03/31 Postdoc (Research) Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
Universidade Nova de Lisboa Centro de Toxicogenómica e Saúde Humana, Portugal
2017/09/01 - 2018/03/31 Postdoc (Research) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2008/08 - 2010/07 Researcher (Research) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Universidade Nova de Lisboa Centro de Toxicogenómica e Saúde Humana, Portugal
2007/04/21 - 2008/07/17 Research Trainee (Research) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2023/11/01 - Current Assistant Professor (University Teacher) Universidade Lusófona de Humanidades e Tecnologias Escola de Psicologia e Ciências da Vida, Portugal
Universidade Lusófona de Humanidades e Tecnologias Escola de Psicologia e Ciências da Vida, Portugal
2019/01/01 - Current Invited Assistant Professor (University Teacher) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Others

Category
Host institution 		Employer
2010/08/01 - 2016/12/15 PhD Student Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
(...)
Projects

Grant

Designation Funders
2018/04/15 - 2019/03/31 BioMAN/DGH/01 - Projeto Incentivo de Estudos de Biomonitorização Humana de Âmbito Nacional (BioMAN)
BioMAN/DGH/01
Post-doc Fellow
Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
 Instituto Nacional de Saúde Doutor Ricardo Jorge IP
Concluded
2017/07/01 - 2018/02/28 DOMAIN DYNAMICS AND CONTROL OF ELECTRON FLUX
FCT-ANR/BEX-BCM/0002/2013
Post-doc Fellow
Universidade Nova de Lisboa Centro de Toxicogenómica e Saúde Humana, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/07 - 2014/06 MicroRNA involvement in breast cancer susceptibility and progression
SFRH/BD/64131/2009
PhD Student Fellow
Universidade Nova de Lisboa Centro de Toxicogenómica e Saúde Humana, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2008/07 - 2010/06 Developmental and Application of SatisfiabilityModels and Algorithms for Haplotype Inference based on Pure Parsimony (SHIPs)
PTDC/EIA/64164/2006
Research Fellow
Universidade Nova de Lisboa Centro de Toxicogenómica e Saúde Humana, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2024 - Current MSCA-Staff Exchange -ONEPathTools
2022.04495.PTDC
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
Submitted
2022 - Current Exploring miRNA signature for Lyme borreliosis Acronym: LymeBiomiR
2022.04495.PTDC
Fundação para a Ciência e a Tecnologia
Not funded
2021/02 - Current Search for immunological signatures and mRNA biomarkers in blood for the differential diagnosis of Lyme borreliosis; Acronym: LYMEBIOPRINT
PTDC/SAL-INF/3114/2021
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
Not funded
2020 - Current Exploring the humoral immune signature and mRNA as blood biomarkers for the laboratory diagnosis of Lyme borreliosis
PTDC/SAL-INF/6284/2020
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Not funded
2021/01/01 - 2025/12/31 Institute of Molecular Medicine João Lobo Antunes
LA/P/0082/2020
10.54499/LA/P/0082/2020
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/04/01 - 2022/02/28 Comprehensive Evaluation of Circulating MicroRNA as Diagnostic and Prognostic Biomarkers in Amyotrophic Lateral Sclerosis
PTDC/MEC-NEU/31195/2017
Post-doc
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2019/12/31 Centre for Toxicogenomics and Human Health
UID/BIM/00009/2019
Universidade NOVA de Lisboa, Portugal

Universidade Nova de Lisboa Centro de Toxicogenómica e Saúde Humana, Portugal

Universidade NOVA de Lisboa NOVA Medical School, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2013/12/31 Strategic Project - UI 9 - 2011-2012
PEst-OE/SAU/UI0009/2011
Universidade Nova de Lisboa Centro de Toxicogenómica e Saúde Humana, Portugal

Universidade NOVA de Lisboa NOVA Medical School, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. S., Antnio; Gomes, BC; Martins, Clia; Gromicho, Marta; G., Nuno; S., Patrcia; Rueff, Jos. "DNA Repair and Resistance to Cancer Therapy". In New Research Directions in DNA Repair. InTech, 2013.
    10.5772/53952
  2. N., Susana; Gomes, BC; Rueff, Jose; Francisco, Jorge. "DNA Repair Perspectives in Thyroid and Breast Cancer: The Role of DNA Repair Polymorphisms". In DNA Repair and Human Health. InTech, 2011.
    10.5772/22944
  3. SN Silva; Bruno Costa Gomes; Jose Rueff; Jorge Francisco Dias Rodrigues Gaspar. "DNA Repair perspectives in Thyroid and Breast cancer". In the role of DNA repair polymorphisms, 459-484. In-teh, 2011.
    DOI: 10.5772/22944
  4. Anunciação, Orlando; Gomes, BC; Vinga, Susana; Gaspar, Jorge; Oliveira, Arlindo L.; Rueff, José. "A Data Mining Approach for the Detection of High-Risk Breast Cancer Groups". In Advances in Intelligent and Soft Computing, 43-51. Springer Berlin Heidelberg, 2010.
    10.1007/978-3-642-13214-8_6
Conference poster
  1. Diogo Serranito Tibério; Catarina Silva; Luis Vieira; Rodrigues, António Sebastião; Nunes Silva, Susana; Bruno Costa Gomes. "DNA methylation profiling of breast cancer cell lines through Nanopore sequencing". Paper presented in 28th Annual Meeting Sociedade Portuguesa de Genética Humana, 2024.
  2. Laura Claudino; Catarina Silva; Luis Vieira; Rodrigues, António Sebastião; Bruno Costa Gomes; Nunes Silva, Susana. "Identifying Alternative Splicing Isoforms in Breast Cancer Cell Lines through Nanopore Sequencing". Paper presented in 28th Annual Meeting Sociedade Portuguesa de Genética Humana, 2024.
  3. Barata, Isabel S; Bruno Costa Gomes; António Sebastão Rodrigues; Rueff, José; Kranendonk, Michel; Esteves, Francisco. "Differential Expression of Phase I Drug Metabolism Enzymes in Doxorubicin Resistant Breast Cancer Cells". Paper presented in 26th Annual Meeting Sociedade Portuguesa de Genética Humana, 2022.
  4. Ana Rita Pisco; Gomes, BC; Marta Gromicho; Pronto-Laborinho, Ana Catarina; José Rueff (0E15-908D-EA21); Mamede de Carvalho; António Sebastião Rodrigues (9012-44BE-F79D). "Assessment of microRNAs as Biomarkers of disease progression in amyotrophic lateral Sclerosis". Paper presented in 31st International Symposium on ALS/MND, 2020.
  5. Catarina Afonso; Gomes, BC; Louro, Henriqueta; Hermínia Pinhal; Ana Nogueira; S. Reis; Célia Ventura; et al. "Occupational Exposure To Hexavalent Chromium - The Portuguese Case Within The Collaborative European Human Biological Monitoring Study". Paper presented in 11th International Symposium on Biological Monitoring in Occupational and Environmental Health (ISBM-11), 2019.
  6. Maria João Aleixo da Silva (7710-643D-97A3); Louro, Henriqueta; Susana Viegas (A919-7318-63DC); Gomes, BC; Tiina Santonen; Andreas Kortenkamp; Erik Lebret. "A Case Study On Occupational Exposure To Chromium (Vi), Nickel, Pah Mixtures And Lung Cancer". Paper presented in 11th International Symposium on Biological Monitoring in Occupational and Environmental Health, 2019.
  7. Gomes, BC; Louro, Henriqueta; Pasi Huuskonen; Tiina Santonen; Katriina Huumonen; Sophie Ndaw; Mariana F. Fernández; Maria João Aleixo da Silva (7710-643D-97A3). "The use of effect biomarkers in hexavalent chromium human biomonitoring studies: a critical review". Paper presented in ISES Europe 2019, 2019.
  8. Diana Isabel Viana da Fonseca Campelo Delgado (7212-9762-DF4E); Francisco Esteves; Bernardo Brito e Palma; Gomes, BC; José Rueff; T. Lautier; P. Urban; G. Truan; Michel Kranendonk. "Probing the role of the hinge segment of cytochrome P450 oxidoreductase in the interaction with cytochrome P450". Paper presented in 9as Jornadas Científicas do IHMT, Instituto de Higiene e Medicina Tropical - Universidade NOVA de Lisboa, 2018.
  9. Diana Isabel Viana da Fonseca Campelo Delgado (7212-9762-DF4E); Francisco Esteves; Bernardo Brito e Palma; Gomes, BC; José Rueff; T. Lautier; P. Urban; G. Truan; Michel Kranendonk. "Mutants of cytochrome P450 oxidoreductase: probing the role of the hinge segment in the interaction with cytochrome P450s". Paper presented in IV NOVA Health Genetics Workshop, Universidade NOVA de Lisboa Rectorate, 2018.
  10. Diana Isabel Viana da Fonseca Campelo Delgado (7212-9762-DF4E); Francisco Esteves; Bernardo Brito e Palma; Gomes, BC; José Rueff; T. Lautier; P. Urban; G. Truan; Michel Kranendonk. "Probing the Role of the Hinge Segment of Cytochrome P450 oxidoreductase in the Interaction with Cytochrome P450". Paper presented in 2nd NMS Symposium on Chronic Diseases and Translational Science 2018. CEDOC Chronic Diseases, 2018.
  11. LS Santos; SN Silva; Octávia Monteiro Gil; Bruno Costa Gomes; HN Bastos; TC Ferreira; E Limbert; José Rueff. "The potential impact of DNA Repair SNPs on DNA damage levels of lymphocytes from 131I-treated thyroid cancer patients". Paper presented in European Society for Pharmacogenomics and Personalized Therapy, 4th Conference, 2017.
  12. LS Santos; SN Silva; Bruno Costa Gomes; R Gouveia; AP Azevedo; I Manita; Octávia Monteiro Gil; et al. "The potential contribution of DNA repair SNPs to thyroid cancer susceptibility". Paper presented in The potential contribution of DNA repair SNPs to thyroid cancer susceptibility, 2016.
  13. Gomes, BC; Bruno Santos; António Sebastião Rodrigues; José Rueff. "miR-200c and miR-203 misexpression in a Portuguese breast cancer population and their association with clinicopathological characteristics". Paper presented in 18th meeting of the Sociedade Portuguesa de Genética Humana, 2014.
  14. Gomes, BC; Bruno Santos; José Rueff; António Sebastião Rodrigues. "Immunohistochemistry detection of putative miR-200c and miR-203 Targets in Breast Cancer Patients.". Paper presented in 18th meeting of the Sociedade Portuguesa de Genética Humana, 2014.
  15. Gomes, BC; Marta Gromicho; José Rueff; António Sebastião Rodrigues. "Epigenetic alterations of microRNAs 124-1 and 200c during acquired resistance to Imatinib in K562 CML cells". Paper presented in 15th International Conference on Chronic Myeloid Leukemia: Biology and Therapy, 2013.
  16. Gomes, BC; Marta Gromicho; António Sebastião Rodrigues; José Rueff. "Methylation status of selected microRNAs in a Chronic Myeloid Leukaemia cell line (K562) and their relationship with therapy response". Paper presented in 17th ECCO – 38th ESMO – 32nd ESTRO European Cancer Congress, 2013.
  17. Gomes, BC; José Rueff; Jorge Gaspar; Susana Nunes da Silva; Luís Silva Santos; Rita Gouveia; Ana Paula Azevedo; Octávia Monteiro Gil; Edward Limbert. "The role of CCNH Val270Ala and other nucleotide excision repair polymorphisms on individual susceptibility towards thyroid cancer". Paper presented in 6th Santorini Conference Biologie Prospective 2012 - Systems Biology and Personalized Health Science and Translation, 2012.
  18. Gomes, BC; José Rueff; António Sebastião Rodrigues. "Profiling of microRNA expression in breast cell lines of different tumourigenicity". Paper presented in 15th Meeting of the Sociedade Portuguesa de Genética Humana - SPGH, 2011.
  19. Pingarilho, Marta; Oliveira, Nuno G.; Martins, Célia; Bruno Costa Gomes; Fernandes, Ana S.; Martins, Vanda; Silva, Anatália R.; Rueff, José; Gaspar, Jorge F.. "Abstract 4199: Genetic variation in the in vitro genotoxic response to glycidamide and gene expression of DNA repair genes". Paper presented in AACR 102nd Annual Meeting 2011, 2011.
    10.1158/1538-7445.am2011-4199
  20. Gomes, BC; Rita Gouveia; Susana Nunes da Silva; Hélder Bastos; Sandra Branco; Mónica Antão; Ana Paula Azevedo; et al. "Polymorphisms in DNA repair genes and non-familiar thyroid cancer risk.". Paper presented in The Future of Molecular Epidemiology: New Tools, Biomarkers and Opportunities, 2010.
  21. Gomes, BC; Marta Pingarilho; Nuno G. Oliveira; Celia Martins; José Rueff; Jorge Gaspar. "Interindividual Variability in the In Vitro Genotoxic Response to Glycidamide: Role of BER and NER Genetic Polymorphisms.". Paper presented in Environmental Mutagen Society 40th Annual Meeting, 2009.
  22. Gomes, BC; Susana Nunes da Silva; Ana Paula Azevedo; José Rueff; Jorge Gaspar. "Polymorphisms in genes of the Non-Homologous End-Joining DNA repair pathway and thyroid cancer risk.". Paper presented in Candidate Pathways, Whole Genome Scans: Reconciling Results, Looking into the Future, 2008.
Journal article
  1. Susana Viegas; Carla Martins; Edna Ribeiro; Carina Ladeira; Hermínia Pinhal; Ana Nogueira; Sílvia Santos; et al. Corresponding author: Louro, Henriqueta. "HBM4EU chromates study: the Portuguese integrated and harmonized study on exposure to hexavalent chromium and related early effects". Annals of Work Exposures and Health (2024): wxae091. https://doi.org/10.1093/annweh/wxae091.
    Published
  2. Bruno Costa Gomes; Nuno Peixinho; Rita Pisco; Marta Gromicho; Ana Catarina Pronto-Laborinho; José Rueff; Mamede de Carvalho; António Sebastião Rodrigues. "Differential Expression of miRNAs in Amyotrophic Lateral Sclerosis Patients". Molecular Neurobiology (2023): https://doi.org/10.1007/s12035-023-03520-7.
    10.1007/s12035-023-03520-7
  3. Isabel S. Barata; Bruno Costa Gomes; Antonio Sebastião Rodrigues; José Rueff; M Kranendonk; Francisco Esteves. "The Complex Dynamic of Phase I Drug Metabolism in the Early Stages of Doxorubicin Resistance in Breast Cancer Cells". Genes (2022): https://www.mdpi.com/2073-4425/13/11/1977.
    10.3390/genes13111977
  4. Ana Tavares; Kukka Aimonen; Sophie Ndaw; Aleksandra Fucic; Julia Catalán; Radu - Corneliu Duca; Lode Godderis; et al. "HBM4EU Chromates Study—Genotoxicity and Oxidative Stress Biomarkers in Workers Exposed to Hexavalent Chromium". Toxics (2022): https://www.mdpi.com/2305-6304/10/8/483.
    10.3390/toxics10080483
  5. Henriqueta Louro; Bruno Costa Gomes; Anne Thoustrup Saber; Anna Laura Iamiceli; Thomas Göen; Kate Jones; Andromachi Katsonouri; et al. "The Use of Human Biomonitoring to Assess Occupational Exposure to PAHs in Europe: A Comprehensive Review". Toxics (2022): https://www.mdpi.com/2305-6304/10/8/480.
    10.3390/toxics10080480
  6. Nunes Silva, Susana; Gomes, BC; André, Saudade; Felix, Ana; Rodrigues, António Sebastião; Rueff, José. "Male and female breast cancer: the two faces of the same genetic susceptibility coin". Breast Cancer Research and Treatment 188 1 (2021): 295-305. http://dx.doi.org/10.1007/s10549-021-06159-x.
    10.1007/s10549-021-06159-x
  7. Ventura, Célia; Gomes, Bruno Costa; Oberemm, Axel; Louro, Henriqueta; Huuskonen, Pasi; Mustieles, Vicente; Fernández, Mariana F.; et al. "Biomarkers of effect as determined in human biomonitoring studies on hexavalent chromium and cadmium in the period 2008-2020". Environmental Research (2021): 110998. http://dx.doi.org/10.1016/j.envres.2021.110998.
    10.1016/j.envres.2021.110998
  8. Araújo, Marília Ladeira de; Gomes, Bruno Costa; Devóz, Paula Pícoli; Duarte, Nathália de Assis Aguilar; Ribeiro, Diego Luis; Araújo, Adriana Ladeira de; Batista, Bruno Lemos; et al. "Association Between miR-148a and DNA Methylation Profile in Individuals Exposed to Lead (Pb)". Frontiers in Genetics 12 (2021): http://dx.doi.org/10.3389/fgene.2021.620744.
    10.3389/fgene.2021.620744
  9. Santos, Luis S.; Octávia Monteiro Gil; SN Silva; Bruno Costa Gomes; Teresa C. Ferreira; Edward Limbert; José Rueff. "Micronuclei Formation upon Radioiodine Therapy for Well-Differentiated Thyroid Cancer: The Influence of DNA Repair Genes Variants". Genes (2020): https://www.mdpi.com/2073-4425/11/9/1083.
    10.3390/genes11091083
  10. Gomes, Bruno C.; Honrado, Mónica; Armada, Ana; Viveiros, Miguel; Rueff, José; Rodrigues, António S.. "ABC Efflux Transporters and the Circuitry of miRNAs: Kinetics of Expression in Cancer Drug Resistance". International Journal of Molecular Sciences 21 8 (2020): 2985. http://dx.doi.org/10.3390/ijms21082985.
    10.3390/ijms21082985
  11. Esteves, Francisco; Campelo, Diana; Gomes, BC; Urban, Philippe; Bozonnet, Sophie; Lautier, Thomas; Rueff, José; Truan, Gilles; Kranendonk, Michel. "The Role of the FMN-Domain of Human Cytochrome P450 Oxidoreductase in Its Promiscuous Interactions With Structurally Diverse Redox Partners". Frontiers in Pharmacology 11 (2020): http://dx.doi.org/10.3389/fphar.2020.00299.
    10.3389/fphar.2020.00299
  12. Santos LS; Gomes, BC; Bastos H; Gil OM; Azevedo AP; Ferreira; Limbert E; Silva SN; Rueff J. "Thyroid Cancer: The Quest for Genetic Susceptibility Involving DNA Repair Genes". Genes 10 8 (2019): 586. http://dx.doi.org/10.3390/genes10080586.
    10.3390/genes10080586
  13. Santonen T; Alimonti A; Bocca B; Duca RC; Galea KS; Godderis L; Göen T; et al. "Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium.". Environmental research (2019): http://europepmc.org/abstract/med/31330491.
    10.1016/j.envres.2019.108583
  14. Armada, Ana; Gomes, BC; Viveiros, Miguel; Rueff, José; Rodrigues, António Sebastião. "Regulation of ABCB1 activity by microRNA-200c and microRNA-203a in breast cancer cells: the quest for microRNAs’ involvement in cancer drug resistance". Cancer Drug Resistance (2019): http://dx.doi.org/10.20517/cdr.2019.24.
    10.20517/cdr.2019.24
  15. Gomes, BC; Rueff, José; Rodrigues, António Sebastião. "MicroRNAs and cancer drug resistance: over two thousand characters in search of a role". Cancer Drug Resistance (2019): http://dx.doi.org/10.20517/cdr.2019.55.
    10.20517/cdr.2019.55
  16. Campelo, Diana; Esteves, Francisco; Palma, Bernardo Brito; Gomes, BC; Rueff, José; Lautier, Thomas; Urban, Philippe; Truan, Gilles; Kranendonk, Michel. "Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450". International Journal of Molecular Sciences 19 12 (2018): 3914. http://dx.doi.org/10.3390/ijms19123914.
    10.3390/ijms19123914
  17. Brás A; Rodrigues AS; Gomes, BC; Rueff J. "Down syndrome and microRNAs.". Biomedical Reports (2018): http://europepmc.org/abstract/med/29403643.
    10.3892/br.2017.1019
  18. D' Oliveira Martins F; Gomes, BC; Rodrigues AS; Rueff J. "Genetic Susceptibility in Acute Pancreatitis: Genotyping of GSTM1, GSTT1, GSTP1, CASP7, CASP8, CASP9, CASP10, LTA, TNFRSF1B, and TP53 Gene Variants.". (2017): http://europepmc.org/abstract/med/27984487.
  19. Gomes, BC; Martins M; Lopes P; Morujão I; Oliveira M; Araújo A; Rueff J; Rodrigues AS. "Prognostic value of microRNA-203a expression in breast cancer.". (2016): http://europepmc.org/abstract/med/27431784.
    10.3892/or.2016.4913
  20. Gomes, BC; Rueff J; Rodrigues AS. "MicroRNAs and Cancer Drug Resistance.". (2016): http://europepmc.org/abstract/med/26910073.
    10.1007/978-1-4939-3347-1_9
  21. Gomes, BC; Santos B; Rueff J; Rodrigues AS. "Methods for Studying MicroRNA Expression and Their Targets in Formalin-Fixed, Paraffin-Embedded (FFPE) Breast Cancer Tissues.". (2016): http://europepmc.org/abstract/med/26910075.
    10.1007/978-1-4939-3347-1_11
  22. Santos LS; Gomes, BC; Gouveia R; Silva SN; Azevedo AP; Camacho V; Manita I; et al. "The role of CCNH Val270Ala (rs2230641) and other nucleotide excision repair polymorphisms in individual susceptibility to well-differentiated thyroid cancer.". (2013): http://europepmc.org/abstract/med/23982724.
    10.3892/or.2013.2702
  23. Pingarilho M; Oliveira NG; Martins C; Gomes, BC; Fernandes AS; Martins V; Labilloy A; et al. "Induction of sister chromatid exchange by acrylamide and glycidamide in human lymphocytes: role of polymorphisms in detoxification and DNA-repair genes in the genotoxicity of glycidamide.". (2013): http://europepmc.org/abstract/med/23376767.
    10.1016/j.mrgentox.2012.12.013
  24. Gomes, BC; Silva SN; Azevedo AP; Manita I; Gil OM; Ferreira TC; Limbert E; Rueff J; Gaspar JF. "The role of common variants of non-homologous end-joining repair genes XRCC4, LIG4 and Ku80 in thyroid cancer risk.". (2010): http://europepmc.org/abstract/med/20811692.
  25. Silva SN; Tomar M; Paulo C; Gomes, BC; Azevedo AP; Teixeira V; Pina JE; Rueff J; Gaspar JF. "Breast cancer risk and common single nucleotide polymorphisms in homologous recombination DNA repair pathway genes XRCC2, XRCC3, NBS1 and RAD51.". (2010): http://europepmc.org/abstract/med/20004634.
    10.1016/j.canep.2009.11.002
Thesis / Dissertation
  1. Gomes, BC. "MICRORNA INVOLVEMENT IN BREAST CANCER SUSCEPTIBILITY AND PROGRESSION". PhD, Universidade Nova de Lisboa Faculdade de Ciências Médicas, 2016. http://hdl.handle.net/10362/19662.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2018 Probing the role of the hinge segment of Cytochrome P450 Oxireductase in the interaction with Cytochrome p450 2nd NMS Symposium on Chronic Diseases and Translational Science 2018
Universidade Nova de Lisboa Faculdade de Ciências Médicas (Lisbon, Portugal)
2015/10/09 miR-200c and miR-203 expression in a Portuguese breast carcinoma population and their association with clinicopathological characteristics 1st Workshop of Genetics – NOVA Health
Universidade Nova de Lisboa (Lisbon, Portugal)
2012/05/28 Epigenetic Regulation of microRNAs Expression in Breast Cancer Cell Lines XXXVII Jornadas Portuguesas de Genética
Sociedade Portuguesa de Genética (Lisbon, Portugal)
2010/06/16 A Data Minning Approach for the Detection of High-Risk Breast Cancer Groups International Workshop on Practical Applications of Computational Biology & Bioinformatics
(Guimarães, Portugal)
2009/04/30 Association of polymorphisms in genes of the non-homologous end-joining DNA repair pathway with non-familial thyroid cancer risk XXXIV Jornadas Portuguesas de Genética
Sociedade Portuguesa de Genética (Lisbon, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023/09/01 - 2024/12 DNA METHYLATION PROFILING OF BREAST CANCER CELL LINES THROUGH NANOPORE SEQUENCING
Supervisor of Diogo Tibério
 Master in Biochemistry for Health (Master)
Universidade NOVA de Lisboa NOVA Medical School, Portugal
2024/03/01 - 2024/07/31 Estabelecimento de modelos celulares resistentes a agentes antineoplásicos
Supervisor of Hélio Medina
 Biology (Degree)
Universidade Lusófona de Humanidades e Tecnologias Escola de Psicologia e Ciências da Vida, Portugal
2024/03/01 - 2024/07/31 Avaliação de danos genómicos através do Comet Assay
Co-supervisor of Catarina Fernandes
 Biology (Degree)
Universidade Lusófona de Humanidades e Tecnologias Escola de Psicologia e Ciências da Vida, Portugal
2024/02/01 - 2024/07/31 EXOSOME ANALYSIS IN CULTURE MEDIUM OF HUMAN BLASTOCYSTS RETRIEVED POST-INVASIVE TROPHECTODERM BIOPSY: POTENTIAL USE AS BIOMARKERS FOR EMBRYONIC VIABILITY
Supervisor
 Embriology and Human Reproduction (Master)
Universidade Lusófona de Humanidades e Tecnologias Escola de Psicologia e Ciências da Vida, Portugal
2020/09/01 - 2022/05 Role of microRNAs and epigenetic modifications in paclitaxel resistance in a breast cancer cell line model
Supervisor
 Bioquímica para a Saúde (Master)
Universidade Nova de Lisboa, Portugal
2020/09/01 - 2022/02/07 Role of microRNAs in cancer drug resistance
Co-supervisor
 Bioquímica para a Saúde (Master)
Universidade Nova de Lisboa, Portugal
2019/09/01 - 2021/04/15 Assessment of microRNAs as biomarkers of disease progression in amyotrophic lateral sclerosis
Supervisor
 Bioquímica para a Saúde (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2018/09/01 - 2020/07/15 Influence of microRNAs on cancer drug resistance
Co-supervisor
 Genética Molecular e Biomedicina (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013/07/01 - 2014/11/01 Immunohistochemistry detection of putative miR-200c and miR-203 Targets in Breast Cancer Patients
Co-supervisor
 Genética Molecular e Biomedicina (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2024/10/24 Aplicabilidade de um software de assistência à seleção embrionária baseado num algoritmo de IA a uma população com indicação para PGT-A no contexto legal português.
(Thesis) Main arguer
 ANA ALEXANDRA MARQUES PÓVOA (Master)
Universidade Lusófona de Humanidades e Tecnologias Escola de Psicologia e Ciências da Vida, Portugal
2024/10/24 Vitrificação de Embriões: Sistema Fechado vs Sistema Aberto
President of the jury
 ANA CATARINA DOS SANTOS REIS (Master)
Universidade Lusófona de Humanidades e Tecnologias Escola de Psicologia e Ciências da Vida, Portugal
2024/07/24 EXOSOME ANALYSIS IN CULTURE MEDIUM OF HUMAN BLASTOCYSTS RETRIEVED POST-INVASIVE TROPHECTODERM BIOPSY: POTENTIAL USE AS BIOMARKERS FOR EMBRYONIC VIABILITY
Supervisor
 Mariana Belchior Lourenço (Master)
Universidade Lusófona de Humanidades e Tecnologias Escola de Psicologia e Ciências da Vida, Portugal
2023/05/19 Identification of de-regulated circulating microRNAs as putative biomarkers in Amyotrophic Lateral Sclerosis
Supervisor
 Nuno Elias (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2022/04/21 Role microRNAs and epigenetics modifications in paclitaxel resistance in a brest cancer cell line model
Supervisor
 Catarina Duarte (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2021/04/15 Assessment of microRNAs as biomarkers of disease progression in amyotrophic lateral sclerosis
Supervisor
 Ana Rita Pisco (Master)
Universidade NOVA de Lisboa NOVA Medical School, Portugal

Committee member

Activity description
Role 		Institution / Organization
2019/10/01 - 2021/10/01 Post-doctoral Committee member at Centro de Estudos de Doenças Crónicas (CEDOC) from Universidade NOVA de Lisboa. This committee represents all post-doctoral researchers from CEDOC and aim to defend the rights of post-doctoral researchers and carry out activities to disseminate the science that is carried out at the center. As example, this committee is responsible for the organization of a bianual symposium at CEDOC, that is focused on translational science.
Member
 Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal