Márcia Alexandra da Silva Correia (1111-FE8C-4A3D)

Curriculum Vitae

Márcia Alexandra da Silva Correia

I graduated in Biochemistry at Universidade de Lisboa in 2004 and completed my PhD in Science and Animal Technology at Universidade Técnica de Lisboa in 2010. During the PhD I developed my scientific expertise in molecular and structural biology, and I made several relevant contributions in the field of carbohydrate-active enzymes (CAZYmes). After my PhD, I joined the protein crystallography group of Prof. Maria João Romão at UCIBIO, NOVA-FCT. The use of protein crystallography to solve different biological problems has been among my main interests, and I have been involved in different topics in structural-activity studies. In 2018, I was awarded a 6-year contract as a Researcher at FCT NOVA (DL57 contract) with emphasis on X-ray Crystallography and Molecular Biology. My research activity resulted in 20 peer-reviewed publications (8 as first author) and 2 book chapters (1 as corresponding author), with over 572 citations. Since 2011, I am also committed to teaching, being involved in several practical classes of 1st and 2nd Cycle in Biochemistry and Biotechnology at DQ-NOVA-FCT, supervision of 3 MSc thesis (1 as co-supervisor) and 5 BSc students and participation in 1 PhD and 6 BSc committee thesis. I actively participated in 3 INSTRUCT international courses, ISBio2014, ISBio2015 and ECS7 as a lecturer of the ITC and the X-ray modules. Besides all my research activities, since October 2016 I started with a different path in research, and I was appointed as lab manager of the Macromolecular Crystallography Lab (UCIBIO@NOVA) where I have overseen the management of all financed projects including allocated human, material, and financial resources. I have implemented methodologies and good practices for better management of the project’s resources and of any other linked projects that may influence the outcome of the current ones. I have given support for various techniques in Structural Molecular Biology, including protein cloning, expression, purification, biophysical characterization, and crystallization tasks for other researchers from the Macromolecular Crystallography group (headed by Prof Maria Joao Romao) as well as from the Functional Glycobiology groups (headed by Prof Angelina Palma), since these 2 researcher groups share common lab space, resources, and facilities. Additionally, I am the mother of two children, born in 2009 and 2014.

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Identification

Personal identification

Full name: Márcia Alexandra da Silva Correia

Citation names

Correia, Márcia
Correia, M. A. S.

Author identifiers

Ciência ID: 1111-FE8C-4A3D
ORCID iD: 0000-0003-0636-8095
Researcher Id: D-2077-2013

Email addresses

mad.correia@fct.unl.pt (Professional)

Telephones

Telephone

212948300 Ext.: 10962 (Professional)

Websites

https://www.requimte.pt/ucibio/people/marcia-correia (Professional)

Knowledge fields

Natural sciences - Biological Sciences - Biochemistry
Natural sciences - Biological Sciences - Molecular Biology
Natural sciences - Biological Sciences - Biophysics

Languages

Language	Speaking	Reading	Writing	Listening
English	Advanced (C1)	Proficiency (C2)	Advanced (C1)	Advanced (C1)
Portuguese (Mother tongue)
French	Beginner (A1)	Elementary (A2)	Beginner (A1)	Intermediate (B1)

Education

	Degree	Classification
2010/06/01 - 2016/10/31 Concluded	Postdoc - "Nitric oxide synthase targeting with re(i)/99mtc(i)-complexes containing l-arg derivatives: a structure-activity study" (Pós-doutoramento) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2005/01 - 2010/05/14 Concluded	Ciências Veterinárias (Doutoramento) Major in Ciência e Tecnologia Animal Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal "Structural and functional insights into the role of Carbohydrate Esterases and Carbohydrate Binding Modules in Plant Cell Wall Hydrolysis" (THESIS/DISSERTATION)	Unanimously approved
1999/09 - 2004/06 Concluded	Bioquímica (Licenciatura) Universidade de Lisboa Faculdade de Ciências, Portugal "Genetic polymorphisms of glutathione S-transferase in different human pathologies." (THESIS/DISSERTATION)	16

Affiliation

Science

	Category Host institution	Employer
2018/12/19 - Current	Contracted Researcher (Research)	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

2010/06/01 - 2016/05/31	Postdoc (Research)	Fundação para a Ciência e a Tecnologia, I.P., Portugal
	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2009/02/01 - 2009/03/31	Research Trainee (Research)	Newcastle University Institute for Cell and Molecular Biosciences, United Kingdom
	Newcastle University Institute for Cell and Molecular Biosciences, United Kingdom
2006/10/01 - 2007/01/31	Research Trainee (Research)	Newcastle University Institute for Cell and Molecular Biosciences, United Kingdom
	Newcastle University Institute for Cell and Molecular Biosciences, United Kingdom

Others

	Category Host institution	Employer
2016/11/01 - 2018/12/18	Research fellow (BPD) (Project FCT UID/Multi/04378/2014)	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
	Universidade Nova de Lisboa, Portugal
2005/01/01 - 2010/05/14	Research fellow (BD) (SFRH/BD/23784/2005)	Fundação para a Ciência e a Tecnologia, I.P., Portugal
	Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal

Projects

Grant

	Designation	Funders
2016/11/01 - 2018/12/18	Applied Molecular Biosciences Unit UID/Multi/04378/2013 Post-doc Fellow REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal	Concluded
2010/06/01 - 2016/10/31	Re(I)/99mTc(I) complexes containing L-arginine derivatives as substrates or inhibitors of Nitric Oxide Synthase: A structure-activity study SFRH/BPD/64917/2009 Post-doc Fellow REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2006/01/01 - 2010/05/14	Structural and functional insights into the role of Carbohydrate Esterases and Carbohydrate Binding Modules in Plant Cell Wall Hydrolysis SFRH/BD/23784/2005 PhD Student Fellow Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Contract

	Designation	Funders
2023/03/01 - 2026/02/28	Descoberta de proteínas do microbioma humano selectivas para O-glicanos ¿ ferramentas para novas abordagens na investigação em cancro 2022.06104.PTDC Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2021/01/01 - 2025/12/31	Instituto para a Saúde e a Bioeconomia LA/P/0140/2020 10.54499/LA/P/0140/2020 Post-doc Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal Universidade NOVA de Lisboa, Portugal INESC Microsistemas e Nanotecnologias, Portugal Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Associação para a Inovação e Desenvolvimento da FCT, Portugal Unidade de Ciências Biomoleculares Aplicadas, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2020/01/01 - 2024/12/19	Unidade de Ciências Biomoleculares Aplicadas UIDB/04378/2020 10.54499/UIDB/04378/2020 Post-doc Universidade NOVA de Lisboa, Portugal Unidade de Ciências Biomoleculares Aplicadas, Portugal Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal Universidade do Porto, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2020/01/01 - 2024/12/19	Unidade de Ciências Biomoleculares Aplicadas UIDP/04378/2020 10.54499/UIDP/04378/2020 Post-doc Universidade NOVA de Lisboa, Portugal Unidade de Ciências Biomoleculares Aplicadas, Portugal Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal Universidade do Porto, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2022/01 - 2024/01/16	Structural and biochemical characterization of PHA synthases towards novel Polyhydroxyalkanoates EXPL/BIA-BQM/1300/2021 EXPL/BIA-BQM/1300/2021 Co-Principal Investigator (Co-PI) Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal Unidade de Ciências Biomoleculares Aplicadas, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/09 - 2021	Glycan-human microbiome interaction: glycan diversity and recognition in the human gut with impact on health and nutrition PTDC/BIA-MIB/31730/2017 Researcher REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Ongoing
2016/01 - 2019/01	Aldehyde Oxidases in Drug Metabolism and Biocatalysis: Searching for the Substrate Specificity and Catalytic Mechanism<br> Provided by PTCRIS: 139810 PTDC/BBB-BEP/1185/2014 Researcher REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2016 - 2019	Molecular determinants of bacterial cellulosome diversity in different ecological niches. PTDC/BIA-MIC/5947/2014 Post-doc Fellow Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2016 - 2019	Redução de CO2 para a produção de biocombustíveis sustentáveis PTDC/BBB-EBB/2723/2014 Post-doc Fellow Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2016/01 - 2018/12	An integrative structural biology approach to characterise the protein-carbohydrate microbial recognition Provided by PTCRIS: 139494 PTDC/BBB-BEP/0869/2014 Researcher REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2013/07 - 2016/06	Modern Structural Biology: Resources for the advancement of in-house X-ray Crystallography 125363 Provided by PTCRIS: 125363 RECI/BBB-BEP/0124/2012 Post-doc Fellow REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2014/11 - 2015/04	Alvejamento da Óxido Nítrico Sintase com complexos de ReI/99mTcI contendo derivados da L-Arg: Um estudo estrutura-actividade PTDC/QUI-QUI/121752/2010 Post-doc Fellow Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2012/02 - 2015/01	Nitric Oxide Synthase targeting with Re(I)/99mTc(I)-complexes containing L-Arg derivatives: A structure-activity study 121752 Provided by PTCRIS: 121752 PTDC/BIA-PRO/118377/2010 SFRH/BPD/64917/2009 Post-doc Fellow	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2012/02 - 2015/01	Mammalian and Bacterial Aldehyde Oxidases: Structure, mechanism and insights into cofactor binding and protein maturation Provided by PTCRIS: 118377 118377 PTDC/BIA-PRO/118377/2010 Post-doc Fellow REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2009/01 - 2011/12	Structure and function of novel carbohydrate-binding modules and cohesin-dockerin protein complexes from Clostridium thermocellum 69732 Provided by PTCRIS: 69732 Post-doc Fellow Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluded

Other

	Designation	Funders
2017/05 - 2017/12	Assessment of natural compounds as novel anti-diabetic drugs REQUIMTE/OPO-LIS/NFB2017 Unidade de Ciências Biomoleculares Aplicadas, Portugal	Unidade de Ciências Biomoleculares Aplicadas Concluded

Outputs

Publications

Book chapter	João Paquete-Ferreira; Francisco Leisico; Márcia A. S. Correia; Filipa Engrola; Teresa Santos-Silva; Marino F. A. Santos. "Using Small-angle X-ray Scattering to Characterize Biological Systems". In A General Overview and Practical Tips, edited by {\^A, 381-403. Humana Press, 2023. 10.1007/978-1-0716-3147-8_22 Filipa Engrola; João Paquete-Ferreira; Teresa Santos-Silva; Márcia A. S. Correia; Francisco Leisico; Marino F. A. Santos. "Screening of Buffers and Additives for Protein Stabilization by Thermal Shift Assay". In A Practical Approach, edited by {\^A, 199-213. Humana Press, 2023. 10.1007/978-1-0716-3147-8_11
Conference poster	Engrola, Filipa; Correia, Márcia; Viegas, Aldino; Romão, Maria; Santos-Silva, Teresa. "Unveiling the interaction of arsenite oxidase with electron parterns ¿ a structural and biophysical approach". Paper presented in CCP4 Study Weekend 2024: Decision making in MX - how to be a productive structural biologist, 2024. Filipa S. S. Engrola; Correia, Márcia; Santos-Silva, Teresa; Maria Joao Romao. "New insights on the catalytic mechanism of arsenite oxidase". Paper presented in In situ Structural Biology: From Cryo-EM to Integrative Modelling, 2020. Correia, M. A. S.; Virginia M.R. Pires; Joana L.A. Brás; Pedro Bule; Maria Joao Romao; Carlos MGA Fontes. "Stability and ligand promiscuity of type A carbohydrate-binding modules are illustrated by the structure of Spirochaeta thermophila St CBM64C". Paper presented in 6th Meeting of the Synchrotron Radiation Users from Portugal (ENURS), 2017. Najmudin, Shabir; Bule, Pedro; Venditto, Immacolata; Cameron, K; Pires, VMR; Bras, Joana L. A.; Freire, Filipe; et al. "Structural insights into the assembly and function of the Cellulosome from Clostridiato Ruminococci". Paper presented in 6th Meeting of Synchrotron Radiation Users from Portugal, 2017. Correia, M. A. S.; Otrelo-Cardoso, A.R; Teresa Santos-Silva. "The Tungstate ABC transporter – structure and function of the periplasmic TupA". Paper presented in 5th Meeting of the Synchrotron Radiation Users from Portugal (ENURS), 2016. Correia, M. A. S.; Otrelo-Cardoso, A.R; Teresa Santos-Silva; Maria Joao Romao. "Structural insights into a unique periplasmic aldehyde oxidoreductase from Escherichia coli". Paper presented in 6th European Conference of Chemistry for Life Sciences, 2015. Correia, M. A. S.; Otrelo-Cardoso, A.R; Teresa Santos-Silva; Maria Joao Romao. "The unique features revealed by the structure of the periplasmic aldehyde oxidoreductase from Escherichia coli". Paper presented in 4th Meeting of the Synchrotron Radiation Users from Portugal (ENURS), 2015. Correia, M. A. S.; Otrelo-Cardoso, A.R; Santos-Silva, Teresa; Maria Joao Romao. "The structure of the first heterotrimeric periplasmic aldehyde oxidoreductase from Escherichia coli.". Paper presented in 3rd Meeting of Synchrotron Radiation Users from Portugal and ESRF-Day, 2014. Correia, M. A. S.; Otrelo-Cardoso, A.R; Santos-Silva, Teresa; Maria Joao Romao; Leimkuehler, Silke. "Structure of the first monomeric periplasmic aldehyde oxidoreductase from Escherichia coli.". Paper presented in Molybdenum & Tungsten Enzymes Conference, 2013. Correia, M. A. S.; Otrelo-Cardoso, A.R; Santos-Silva, Teresa; Leimkuehler, Silke; Maria Joao Romao. "Structure of a monomeric periplasmic aldehyde oxidoreductase from Escherichia coli: Discover of an unexpected [4Fe-4S] cluster using Synchrotron radiation". Paper presented in 2nd Meeting of Synchrotron Radiation Users from Portugal and ESRF-Day, 2013. Correia, M. A. S.; Prof. José Antonio Mestre Prates, PhD; Carlos MGA Fontes. "A novel carbohydrate-binding module displays specificity for galactose-containing polysaccharides through calcium-mediated oligomerization". Paper presented in 9th Carbohydrate Bioengineering Meeting (CBM9), 2011. Correia, M. A. S.; Prof. José Antonio Mestre Prates, PhD; Gilbert, Harry J.; Carlos MGA Fontes. "A family 35 CBM from Clostridium thermocellum specifically recognizes galactose side-chains of complex polysaccharides". Paper presented in 8th Carbohydrate Bioengineering Meeting (CBM8), 2009. Catarina Guerreiro; Najmudin, Shabir; Carvalho, Ana L.; Correia, M. A. S.; Maria Joao Romao; Carlos MGA Fontes. "Structural basis for the promiscuous specificity of carbohydrate-binding modules from the beta-sandwich super-family". Paper presented in 7th Carbohydrate Bioengineering Meeting (CBM7), 2007. Correia, M. A. S.; José Mestre Prates; Carlos MGA Fontes; Gilbert, Harry J.. "Evidence that a putative new family of CBMs binds to Xyloglucan but not undecorated ß-glucan chains". Paper presented in 7th Carbohydrate Bioengineering Meeting (CBM7), 2007. José Mestre Prates; Najmudin, Shabir; Catarina Guerreiro; Carvalho, Ana Luísa; Correia, M. A. S.; Maria Joao Romao; Gilbert, Harry J.; Carlos MGA Fontes. "Crystal structure of novel CBMs that bind with equal affinity to cellulose and xyloglucan (CelJ CBM44 and CBM30)". Paper presented in XV National Congress of Biochemistry, 2006. Correia, M. A. S.; José Mestre Prates; Carlos MGA Fontes. "Identification of novel carbohydrate-binding modules (CBMs) in the cellulosome of Clostridium thermocellum". Paper presented in XV Congresso Nacional de Bioquímica, 2006. Correia, M. A. S.; Carlos MGA Fontes; José Mestre Prates. "A genome-wide search for the complete repertoire of cellulosomal enzymes in Clostridium thermocellum". Paper presented in Congresso da Sociedade Portuguesa de Ciências Veterinárias, 2005. Correia, M. A. S.; Marinho, Claudia; Bicho, Manuel. "Total plasma glutathione in hipertensive subjects: Possible association between hypertension and oxidative stress". Paper presented in XIV Congresso Nacional de Bioquímica, 2004. Correia, M. A. S.; Marinho, Claúdia; Bicho, Manuel. "Genetic distribution of GSTM1 and GSTT1 in Portuguese hipertensive disease of pregnancy". Paper presented in 14th World Congress of the International Society for the Study of Hypertension in Pregnancy, 2004. Correia, M. A. S.; Marinho, Claúdia; Bicho, Manuel. "Genetic distribution of GSTM1 and GSTT1 in hypertensive portuguese subjects: association with plasma epinephrine oxidase activity". Paper presented in Fourteenth European Meeting on Hypertension, 2004. Correia, M. A. S.; Marinho, Claúdia; Bicho, Manuel. "Genetic distribution of GSTM1 and GSTT1 in different Portuguese populations: association with plasma epinephrine oxidase activity". Paper presented in 6th Portuguese Congress on Free Radicals in Chemistry, Biology and Medicine 1st Luso-Spanish Congress on Free Radicals, 2003.
Journal article	Filipa Engrola; Márcia A.S. Correia; Cameron Watson; Carlos C. Romão; Luis F. Veiros; Maria João Romão; Teresa Santos-Silva; Joanne M. Santini. "Arsenite oxidase in complex with antimonite and arsenite oxyanions: Insights into the catalytic mechanism". Journal of Biological Chemistry (2023): https://doi.org/10.1016/j.jbc.2023.105036. 10.1016/j.jbc.2023.105036 D. Gomes; M.A.S. Correia; M.J. Romão; L.A. Passarinha; A. Sousa. "Integrated approaches for the separation and purification of recombinant HPV16 E6 protein from Escherichia coli crude extracts". Separation and Purification Technology 315 (2023): 123647-123647. http://dx.doi.org/10.1016/j.seppur.2023.123647. 10.1016/j.seppur.2023.123647 Márcia A. S. Correia; Ana M. Gonçalves; Augusto Q. Pedro; Diana M. Oliveira; Adriana E. Oliveira; Marino F. A. Santos; João Queiroz; et al. "Thermofluor-Based Optimization Strategy for the Stabilization of Recombinant Human Soluble Catechol-O-Methyltransferase". International Journal of Molecular Sciences 23 20 (2022): 12298-12298. http://dx.doi.org/10.3390/ijms232012298. 10.3390/ijms232012298 Márcia A. S. Correia; Marlene Duarte; Victor D. Alves; Márcia Correia; Catarina Caseiro; Luís M.A. Ferreira; Maria João Romão; et al. "Structure-function studies can improve binding affinity of cohesin-dockerin interactions for multi-protein assemblies". International Journal of Biological Macromolecules (2022): http://dx.doi.org/10.1016/j.ijbiomac.2022.10.102. 10.1016/j.ijbiomac.2022.10.102 Bras, Natercia F.; Lopes, Filipa A. A.; Correia, M. A. S.; Palma, Angelina S.; Sousa, Sérgio F.; Ramos, Maria João. "Combined in silico and in vitro studies to identify novel antidiabetic flavonoids targeting glycogen phosphorylase". Bioorganic Chemistry 108 (2021): 104552-104552. http://dx.doi.org/10.1016/j.bioorg.2020.104552. Open access • Published • 10.1016/j.bioorg.2020.104552 Kumar, Krishan; Correia, Márcia A.S.; Pires, Virgínia M.R.; Dhillon, Arun; Sharma, Kedar; Rajulapati, Vikky; Fontes, Carlos M.G.A.; Carvalho, Ana Luísa; Goyal, Arun. "Novel insights into the degradation of ß-1,3-glucans by the cellulosome of Clostridium thermocellum revealed by structure and function studies of a family 81 glycoside hydrolase". International Journal of Biological Macromolecules 117 (2018): 890-901. http://dx.doi.org/10.1016/j.ijbiomac.2018.06.003. Published • 10.1016/j.ijbiomac.2018.06.003 Ana Rita Otrelo-Cardoso; Rashmi R. Nair; Márcia A. S. Correia; Raquel S. Correia Cordeiro; Alejandro Panjkovich; Dmitri I. Svergun; Teresa Santos-Silva; Maria G. Rivas. "Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20". Scientific Reports 7 1 (2017): https://doi.org/10.1038/s41598-017-06133-y. 10.1038/s41598-017-06133-y Pires, V.M.R.; Pereira, P.M.M.; Brás, J.L.A.; Correia, M.; Cardoso, V.; Bule, P.; Alves, V.D.; et al. "Stability and ligand promiscuity of type A carbohydrate-binding modules are illustrated by the structure of Spirochaeta thermophila StCBM64C". Journal of Biological Chemistry 292 12 (2017): 4847-4860. https://doi.org/10.1074%2Fjbc.m116.767541. Published • 10.1074/jbc.M116.767541 Correia, M.A.S.; Otrelo-Cardoso, A.R.; Schwuchow, V.; Sigfridsson Clauss, K.G.V.; Haumann, M.; Romão, M.J.; Leimkühler, S.; Santos-Silva, T.. "The Escherichia coli Periplasmic Aldehyde Oxidoreductase Is an Exceptional Member of the Xanthine Oxidase Family of Molybdoenzymes". ACS Chemical Biology 11 10 (2016): 2923-2935. http://www.scopus.com/inward/record.url?eid=2-s2.0-84992170557&partnerID=MN8TOARS. 10.1021/acschembio.6b00572 Otrelo-Cardoso, Ana Rita; Nair, Rashmi R.; Correia, Marcia A. S.; Rivas, Maria G.; Santos-Silva, Teresa. "TupA: A Tungstate Binding Protein in the Periplasm of Desulfovibrio alaskensis G20". International Journal of Molecular Sciences 15 7 (2014): 11783-11798. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000340038500038&KeyUID=WOS:000340038500038. 10.3390/ijms150711783 Otrelo-Cardoso, Ana Rita; da Silva Correia, Marcia Alexandra; Schwuchow, Viola; Svergun, Dmitri I.; Romao, Maria Joao; Leimkuehler, Silke; Santos-Silva, Teresa. "Structural Data on the Periplasmic Aldehyde Oxidoreductase PaoABC from Escherichia coli: SAXS and Preliminary X-ray Crystallography Analysis". International Journal of Molecular Sciences 15 2 (2014): 2223-2236. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000335776400032&KeyUID=WOS:000335776400032. 10.3390/ijms15022223 Correia, Marcia A. S.; Mazumder, Koushik; Bras, Joana L. A.; Firbank, Susan J.; Zhu, Yanping; Lewis, Richard J.; York, William S.; Fontes, Carlos M. G. A.; Gilbert, Harry J.. "Structure and Function of an Arabinoxylan-specific Xylanase". Journal of Biological Chemistry 286 25 (2011): 22510-22520. 10.1074/jbc.M110.217315 Bras, Joana L. A.; Cartmell, Alan; Carvalho, Ana Luisa M.; Verze, Genny; Bayer, Edward A.; Vazana, Yael; Correia, Marcia A. S.; et al. "Structural insights into a unique cellulase fold and mechanism of cellulose hydrolysis". Proceedings of the National Academy of Sciences of the United States of America 108 13 (2011): 5237-5242. Published • 10.1073/pnas.1015006108 Bras, Joana L. A.; Correia, Marcia A. S.; Romao, Maria J.; Prates, Jose A. M.; Fontes, Carlos M. G. A.; Najmudin, Shabir. "Purification, crystallization and preliminary X-ray characterization of the pentamodular arabinoxylanase CtXyl5A from Clostridium thermocellum". Acta Crystallographica Section F-Structural Biology and Crystallization Communications 67 (2011): 833-836. 10.1107/S1744309111020823 Montanier, Cedric Y.; Correia, Marcia A. S.; Flint, James E.; Zhu, Yanping; Basle, Arnaud; McKee, Lauren S.; Prates, Jose A. M.; et al. "A Novel, Noncatalytic Carbohydrate-binding Module Displays Specificity for Galactose-containing Polysaccharides through Calcium-mediated Oligomerization". Journal of Biological Chemistry 286 25 (2011): 22499-22509. 10.1074/jbc.M110.217372 Brás, J.L.A.; Cartmell, A.; Carvalho, A.L.M.; Verzé, G.; Bayer, E.A.; Vazana, Y.; Correia, M.A.S.; et al. "Structural insights into a unique cellulase fold and mechanism of cellulose hydrolysis (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 13, (5237-5242))". Proceedings of the National Academy of Sciences of the United States of America 108 20 (2011): 8525-8525. http://www.scopus.com/inward/record.url?eid=2-s2.0-79957764741&partnerID=MN8TOARS. 10.1073/pnas.1104766108 Correia, Marcia A. S.; Abbott, D. Wade; Gloster, Tracey M.; Fernandes, Vania O.; Prates, Jose A. M.; Montanier, Cedric; Dumon, Claire; et al. "Signature Active Site Architectures Illuminate the Molecular Basis for Ligand Specificity in Family 35 Carbohydrate Binding Module". Biochemistry 49 29 (2010): 6193-6205. 10.1021/bi1006139 Correia, Marcia A. S.; Pires, Virginia M. R.; Gilbert, Harry J.; Bolam, David N.; Fernandes, Vania O.; Alves, Victor D.; Prates, Jose A. M.; Ferreira, Luis M. A.; Fontes, Carlos M. G. A.. "Family 6 carbohydrate-binding modules display multiple beta 1,3-linked glucan-specific binding interfaces". Fems Microbiology Letters 300 1 (2009): 48-57. 10.1111/j.1574-6968.2009.01764.x Montanier, Cedric; van Bueren, Alicia Lammerts; Dumon, Claire; Flint, James E.; Correia, Marcia A.; Prates, Jose A.; Firbank, Susan J.; et al. "Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function". Proceedings of the National Academy of Sciences of the United States of America 106 9 (2009): 3065-3070. 10.1073/pnas.0808972106 Correia, Marcia A. S.; Prates, Jose A. M.; Bras, Joana; Fontes, Carlos M. G. A.; Newman, Joseph A.; Lewis, Richard J.; Gilbert, Harry J.; Flint, James E.. "Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides insights into the mechanism of substrate recognition". 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Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2019/06/28	Lytr from streptococcus dysgalactiae subs. dysgalactiae: A target for biofilm inhibition	8th Meeting of Portuguese Synchrotron Radiation Users (ENURS 2019) (Porto, Portugal)
2019/06/28	Arsenite oxidase: from the substrate analogue to the electron acceptors structural and function insights	8th Meeting of Portuguese Synchrotron Radiation Users (ENURS 2019) (Porto, Portugal)
2015/06	Structural insights into a unique periplasmic aldehyde oxidoreductase from Escherichia coli	6th European Conference of Chemistry for Life Sciences (Lisboa, Portugal)
2008	Identification of a novel family of Carbohydrate-Binding Domains that bind decorations of complex polysaccharides	Congresso Nacional de Bioquímica (Açores, Portugal)
2007/06/14	Aspectos funcionais e estruturais de uma nova familia de CBM’s	Jornadas de pós-graduação da Faculdade de Medicina Veterinária da Universidade Técnica de Lisboa Faculdade de Medicina Veterinária da Universidade Técnica de Lisboa (Lisboa, Portugal)
2004	Actividade do oxidase da adrenalina e o processo inflamatório na hipertensão arterial: Possível associação com o genótipo do GSTT1	1ª reunião da Sociedade Portuguesa de Hipertensão (Porto)
2004	Genetic distribution of GSTM1 and GSTT1 in portuguese women with cervical cancer: association with plasma epinephrine oxidase activity	III Simpósio Internacional HPV e Cancro (Lisboa, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2019/09/01 - 2020/09/01	Assessment of natural compounds as novel anti-diabetic drugs Supervisor of Filipa Lopes	Bioquímica (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/09 - 2019/09	Bacterial arsenite oxidation at the molecular level Co-supervisor of Filipa Sofia Silva Engrola	Bioquímica (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013/09 - 2014/09	Structural and Functional characterization of ModA and TupA proteins belonging to the molybdate and tungstate transport system from Desulfovibrio alaskensis G20 Supervisor	Bioquímica (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2015/07/13 - 2015/07/19	Co-organizer and Speaker of ISBio2015: Course on Integrative Structural Biology - Integrative Structural Biology tools for the study of protein-ligand interactions, speaker on the Isothermal Titration Calorimetry (ITC) module lecture (2015/07/13 - 2015/07/19) Workshop (Co-organisor)	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2014/10/06 - 2014/10/12	Co-organizer and Speaker of ISBio2014: Course on Integrative Structural Biology - Integrative Structural Biology tools for the study of protein-ligand interactions, speaker on the Isothermal Titration Calorimetry (ITC) module lecture (2014/10/06 - 2014/10/12) Workshop (Co-organisor)	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2019/05/26 - 2019/05/31	International School on Biological Crystallization Workshop	International School on Biological Crystallization: ISBC 2019 Universidad de Granada, Spain
2019/02/27 - 2019/02/28	BAG Training sessions for users of the Macromolecular Crystallography (MX) beamlines at the Diamond Light Source Workshop	MX BAG Training 2019 Diamond Light Source Ltd, United Kingdom
2018/05 - 2018/05	BAG Training sessions for users of the Macromolecular Crystallography (MX) beamlines at the European Synchrotron Radiation Facility Workshop	ESRF MX BAG Training 2018 ESRF, France
2013/05/06 - 2013/05/10	Course: Small angle neutron and X-ray scattering from proteins in solution Workshop	EMBO Practical Course. Small angle neutron and X-ray scattering from proteins in solution Institut Laue-Langevin, France
2013/01/03 - 2013/01/05	CCP4 Study Weekend 2013 Workshop	CCP4 Study Weekend Nottingham Trent University, United Kingdom
2012/10/20 - 2012/10/27	The sixth BioCrys course 2012. Workshop	BioCrys 2012 Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2012 - 2012	BAG Training sessions for users of the Macromolecular Crystallography (MX) beamlines at the European Synchrotron Radiation Facility Workshop	BAG Training 2012 ESRF, France
2007 - 2007	Protein Crystallography Course Workshop	Protein Crystallography Course (Monographic Course 2007) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Distinctions

Award

2010	Post-doctoral Grant - reference FCT: SFRH/BPD/64917/2009 Fundação para a Ciência e a Tecnologia, I.P., Portugal
2006	PhD Research Grant - reference FCT: SFRH/BD/23784/2005 Fundação para a Ciência e a Tecnologia, I.P., Portugal