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Identification

Personal identification

Full name
Seidy Pedroso Santana

Citation names

  • Pedroso-Santana Seidy
  • Pedroso Seidy
  • Pedroso Santana S
  • Santana S P

Author identifiers

Ciência ID
1211-62FD-58CE
ORCID iD
0000-0002-2060-1247
Google Scholar ID
https://scholar.google.com.mx/citations?user=3onrw4wAAAAJ&hl=es
Researcher Id
D-4434-2017

Knowledge fields

  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Spanish; Castilian (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2013/01/20 - 2017/06/28
Concluded
Doctor en Ciencias (Física) (Doctor of Philosophy)
Universidad de Sonora, Mexico
"Physical and chemical modifications of diamond and gold nanoparticles in the formation of hybrid nanostructures for use in Biomedicine" (THESIS/DISSERTATION)
2008/06/01 - 2010/06/30
Concluded
Master en Biotecnología (Master)
Centro de Ingenieria Genetica y Biotecnologia, Cuba
"Differential gene expression because of Phycocyanin C and Interferon alpha application in the treatment of Multiple Sclerosis" (THESIS/DISSERTATION)
1998/09/01 - 2003/06/28
Concluded
Licenciado en Microbiología (Bachelor)
Universidad de la Habana Facultad de Biologia, Cuba
"Obtaining a Pichia pastoris multicopy clone with higher HBsAg expression" (THESIS/DISSERTATION)
Affiliation

Science

Category
Host institution
Employer
2023/07/10 - Current Researcher (Research) Universidade de Coimbra, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2021/07/01 - 2023/05/31 Postdoc (Research) Universidad Católica del Norte Facultad de Ciencias del Mar, Chile
2018/03/14 - 2021/03/13 Postdoc (Research) Universidad de Concepción Facultad de Ciencias Biológicas, Chile
2013/01/20 - 2017/06/28 Research Trainee (Research) Universidad de Sonora, Mexico
2003/11/19 - 2012/10/08 Researcher (Research) Centro de Ingenieria Genetica y Biotecnologia, Cuba
Centro de Ingenieria Genetica y Biotecnologia, Cuba

Teaching in Higher Education

Category
Host institution
Employer
2017/12/01 - 2018/05/30 Associate Professor (University Teacher) Universidad Estatal de Sonora, Mexico
Projects

Grant

Designation Funders
2023/07/10 - Current Engineering the immunosuppressive microenvironment in mesothelioma with targeted LipidNanoParticles encapsulating self-amplifying RNA
Post-doc Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
European Research Executive Agency
Ongoing
2018/03/14 - 2021/03/13 Development of nanoencapsulated formulation of immune-stimulant proteins for the treatment of diseases.
3180694
Post-doc
Comisión Nacional de Investigación Científica y Tecnológica Fondo Nacional de Desarrollo Científico y Tecnológico, Chile
Comisión Nacional de Investigación Científica y Tecnológica Fondo Nacional de Desarrollo Científico y Tecnológico
Concluded

Contract

Designation Funders
2021/07/01 - 2023/05/31 Design, development, and characterization of functionalized nanostructures for biomedicine
5
Post-doc
Universidad Católica del Norte, Chile
Concluded
2003/11/19 - 2012/10/08 Genomic and transcriptomic analysis of potential drugs developed by the CIGB. Cloning and expression of recombinant proteins for use in diagnostic tests.
1
Researcher
Concluded
2008/09/01 - 2010/06/30 Differential gene expression because of Phycocyanin C and Interferon alpha application in the treatment of Multiple Sclerosis
2
Master Student Fellow
Concluded

Other

Designation Funders
2013/01/20 - 2017/06/28 Physical and chemical modifications of diamond and gold nanoparticles in the formation of hybrid nanostructures for use in Biomedicine
3
PhD Student Fellow
Concluded
Outputs

Publications

Journal article
  1. Seidy Pedroso Santana; Noralvis Fleitas-Salazar. "The Use of Capping Agents in the Stabilization and Functionalization of Metallic Nanoparticles for Biomedical Applications". Particle & Particle Systems Characterization (2022): 2200146-2200146. http://dx.doi.org/10.1002/ppsc.202200146.
    10.1002/ppsc.202200146
  2. Noralvis Fleitas-Salazar; Emilio Lamazares; Seidy Pedroso Santana; Tomas Kappes; Alain Perez-Alonso; Angela Hidalgo; Claudia Altamirano; et al. "Long-term release of bioactive interferon-alpha from PLGA-chitosan microparticles: In vitro and in vivo studies". Biomaterials Advances (2022): 213167-213167. http://dx.doi.org/10.1016/j.bioadv.2022.213167.
    10.1016/j.bioadv.2022.213167
  3. Fleitas-Salazar, Noralvis; Pedroso-Santana, Seidy; Silva-Campa, Erika; Angulo-Molina, Aracely; Toledo, Jorge R; Riera, Raul; Pedroza-Montero, Martin. "Raman spectroscopy and silver nanoparticles for efficient detection of membrane proteins in living cells". Nanotechnology 32 49 (2021): 495101. http://dx.doi.org/10.1088/1361-6528/ac21ee.
    10.1088/1361-6528/ac21ee
  4. Ramos Thelvia Isabel; Carlos Villacis-Aguirre; Nelson Santiago Vispo; Leandro Santiago Padilla; Seidy Pedroso Santana; Natalie C. Parra; Jorge Roberto Toledo Alonso. "Forms and Methods for Interferon’s Encapsulation". Pharmaceutics (2021): https://www.mdpi.com/1999-4923/13/10/1533.
    10.3390/pharmaceutics13101533
  5. Pasquale Sacco; Seidy Pedroso Santana; Yogesh Kumar; Nicolas JOLY; Martin Patrick; Patrizia Bocchetta. "Ionotropic Gelation of Chitosan Flat Structures and Potential Applications". Molecules (2021): https://www.mdpi.com/1420-3049/26/3/660.
    10.3390/molecules26030660
  6. Pedroso-Santana, Seidy; Lamazares Arcia, Emilio; Fleitas-Salazar, Noralvis; Gancino Guevara, Marlon; Mansilla, Rodrigo; Gómez-Gaete, Carolina; Altamirano, Claudia; et al. "Polymeric nanoencapsulation of alpha interferon increases drug bioavailability and induces a sustained antiviral response in vivo". Materials Science and Engineering: C 116 (2020): 111260. http://dx.doi.org/10.1016/j.msec.2020.111260.
    10.1016/j.msec.2020.111260
  7. Pedroso-Santana, Seidy; Fleitas-Salazar, Noralvis. "Ionotropic gelation method in the synthesis of nanoparticles/microparticles for biomedical purposes". Polymer International 69 5 (2020): 443-447. http://dx.doi.org/10.1002/pi.5970.
    10.1002/pi.5970
  8. Vázquez-Blomquist, Dania; Fernández, Julio Raúl; Miranda, Jamilet; Guillén, Isabel; Pedroso, Seidy; Martín, Alexander; Ochagavia, María Elena; et al. "Gene expression profile in cervical carcinoma cells treated with HeberFERON". Bionatura 3 4 (2018): http://dx.doi.org/10.21931/rb/2018.03.04.3.
    10.21931/rb/2018.03.04.3
  9. Seidy Pedroso-Santana; Noralvis Fleitas-Salazar; Andrei Sarabia-Sainz; Erika Silva-Campa; Araceli Angulo-Molina; Martin Pedroza-Montero; Raul Riera. "Nanodiamonds and gold nanoparticles to obtain a hybrid nanostructure with potential applications in biomedicine". Nanotechnology 29 43 (2018): 435101-435101. https://doi.org/10.1088%2F1361-6528%2Faadad1.
    10.1088/1361-6528/aadad1
  10. Seidy Pedroso-Santana; Noralvis Fleitas-Salazar; Andrei Sarabia-Sainz; Erika Silva-Campa; Alexel Burgara-Estrella; Aracely Angulo-Molina; Rodrigo Melendrez; Martin Pedroza-Montero; Raul Riera. "A nanodiamond-fluorescein conjugate for cell studies". Advances in Natural Sciences: Nanoscience and Nanotechnology 9 1 (2018): 015013-015013. https://doi.org/10.1088%2F2043-6254%2Faaa6f2.
    10.1088/2043-6254/aaa6f2
  11. Fleitas-Salazar, Noralvis; Silva-Campa, Erika; Pedroso-Santana, Seidy; Tanori, Judith; Pedroza-Montero, Martín R.; Riera, Raúl. "Effect of temperature on the synthesis of silver nanoparticles with polyethylene glycol: new insights into the reduction mechanism". Journal of Nanoparticle Research 19 3 (2017): http://dx.doi.org/10.1007/s11051-017-3780-3.
    10.1007/s11051-017-3780-3
  12. Pedroso-Santana, Seidy; Sarabia-Saínz, Andrei; Fleitas-Salazar, Noralvis; Santacruz-Gómez, Karla; Acosta-Elías, Monica; Pedroza-Montero, Martin; Riera, Raul. "Deagglomeration and characterization of detonation nanodiamonds for biomedical applications". Journal of Applied Biomedicine 15 1 (2017): 15-21. http://dx.doi.org/10.1016/j.jab.2016.09.003.
    Published • 10.1016/j.jab.2016.09.003
  13. Galván, José A.; Camacho, Hanlet; Eaton, William W.; Nazabal, Marcelo; Fernández de Cossio, María E.; Guillen, Isabel; Pedroso, Seidy; et al. "Association of gliadin antibodies, HLA alleles, and schizophrenia in Cuban population patients". Bionatura 1 2 (2016): 62-66. http://dx.doi.org/10.21931/rb/2016.01.02.4.
    10.21931/rb/2016.01.02.4
  14. Acosta-Elias, M.; Sarabia-Sainz, A.; Pedroso-Santana, S.; Silva-Campa, E.; Santacruz-Gomez, K.; Angulo-Molina, A.; Castaneda, B.; et al. "Carboxylated nanodiamond and re-oxygenation process of gamma irradiated red blood cells". Physica Status Solidi a-Applications and Materials Science 212 11 (2015): 2437-2444. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000366588100009&KeyUID=WOS:000366588100009.
    10.1002/pssa.201532197
  15. Perera, Yasser; Pedroso, Seidy; Borras-Hidalgo, Orlando; Vazquez, Dania M.; Miranda, Jamilet; Villareal, Adelaida; Falcon, Viviana; et al. "Pharmacologic inhibition of the CK2-mediated phosphorylation of B23/NPM in cancer cells selectively modulates genes related to protein synthesis, energetic metabolism, and ribosomal biogenesis". Molecular and Cellular Biochemistry 404 1-2 (2015): 103-112. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000355433900012&KeyUID=WOS:000355433900012.
    10.1007/s11010-015-2370-x
  16. Marin-Prida, Javier; Pavon-Fuentes, Nancy; Llopiz-Arzuaga, Alexey; Fernandez-Masso, Julio R.; Delgado-Roche, Livan; Mendoza-Mari, Yssel; Santana, Seydi Pedroso; et al. "Phycocyanobilin promotes PC12 cell survival and modulates immune and inflammatory genes and oxidative stress markers in acute cerebral hypoperfusion in rats". Toxicology and Applied Pharmacology 272 1 (2013): 49-60. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000325834200006&KeyUID=WOS:000325834200006.
    10.1016/j.taap.2013.05.021
  17. Pedroso-Santana, Seidy. "An updated approach to Multiple Sclerosis". Biotecnología Aplicada 29 1 (2012): 1-6. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=SCIELO&KeyUT=SCIELO:S1027-28522012000100001&KeyUID=SCIELO:S1027-28522012000100001.
  18. Penton-Rol, Giselle; Nazabal-Galvez, M.; Hanlet, Camacho-Rodriguez; Pedroso-Santana, S.; Fernandez de Cosso, M. E.; Cervantes-Llanos, M.; Cintado-Benitez, A.; et al. "Neuromyelitis optica and Multiple Sclerosis: a view from DNA, RNA and protein profiles.". Multiple Sclerosis Journal 18 12 (2012): 1853-1853. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000312192300136&KeyUID=WOS:000312192300136.
  19. Perez, I. A. G.; Santana, S. P.; Argudin, T. D.; Gardon, D. O. P.. "Analysis of blood processing conditions to obtain high-quality total RNA from human leukocyte concentrate". Genetics and Molecular Research 6 2 (2007): 298-307. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000251696400007&KeyUID=WOS:000251696400007.
  20. "A new NS3 recombinant protein shows improved antigenic properties for HCV diagnosis". Biotecnología Aplicada 23 2 (2006): 94-98. http://elfosscientiae.cigb.edu.cu/ContenidoIssue.asp?ID=80.
    Published
  21. Pedroso, Seidy; Guillen, Isabel Alicia. "Microarray and nanotechnology applications of functional nanoparticles". Combinatorial Chemistry & High Throughput Screening 9 5 (2006): 389-397. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000237961400007&KeyUID=WOS:000237961400007.
    10.2174/138620706777452438
Preprint
  1. "Starch-based hydrogels show relevant properties for tissue engineering and loading of nanoparticulate systems.". 2020. http://dx.doi.org/10.22541/au.158920847.74971326.
    10.22541/au.158920847.74971326
Activities

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2019 - 2022 Synthesis and evaluation of a biocompatible hydrogel incorporated with copper nanoparticles, with potential application in tissue engineering
Co-supervisor
Universidad de Concepción, Chile
2019 - 2019 Synthesis and characterization of in vitro biologically active protein-polymer based nanoparticulate formulations
Co-supervisor of Marlon Gancino
Universidad Yachay Tech, Ecuador

Universidad de Concepción, Chile

Event participation

Activity description
Type of event
Event name
Institution / Organization
2020 - 2020 Presentation at Nanosafety 2020: Protein-loaded nanoparticles obtained by electrospray for the enhancement of antiviral response in the respiratory mucosa. Event organized by the Leibniz Research Association.
Congress
Nanosafety 2020
2020 - 2020 Participation in the course: The 3Rs across Europe, given by Swiss 3R Competence Centre, Virtual event. 2020
Conference
The 3Rs across Europe.
2019 - 2019 Poster presentation: Polymeric biocompatible nanocarriers for drug delivery applications shows preserved biological activity of loaded proteins, in vitro and in vivo.
Congress
Sofarchi 2019
Sociedad de Farmacologia de Chile, Chile
2018 - 2018 Poster presentation: Applications of Nanotechnology in the search for new drugs.
Congress
Sofarchi 2018
Sociedad de Farmacologia de Chile, Chile
2017 - 2017 Poster presentation: Diamond-gold hybrid nanostructure for application in cell studies.
Congress
MRS Fall Meeting 2017
Materials Research Society, United States
2016/08 - 2016/08 Poster presentation: Modification of detonation nanodiamonds for imaging and spectroscopic studies in cells.
Congress
XXV International Materials Research Congress 2016.
2016 - 2016 Poster presentation: Genomic approaches to improve the treatment of tumors with interferons.
Congress
OMICs 2016
Centro de Ingenieria Genetica y Biotecnologia, Cuba
2015 - 2015 Poster presentation: Study of reoxygenation of red blood cells induced by carboxylated nanodiamonds.
Congress
Hasselt Diamond Workshop 2015
2014 - 2014 Poster presentation: Deagglomeration of detonation nanodiamonds using bead assisted sonic disintegration with silica beads. LVII Congreso Nacional de Física Mexico 2014
2012 - 2012 Poster presentation: Quantitative real time PCR for the measurement of genes involved in the mechanism of action of CIGB300 in cervical cancer. Biotecnología Habana 2012
2011 - 2011 Poster presentation: Suppression subtractive hybridization and Bioinformatic applications, a way to select and identify genes associated with a new treatment for Multiple Sclerosis.
Congress
II International Congress on Immunopharmacology.
2006 - 2006 Poster presentation: Microarray and Nanotechnology applications in gene expression studies.
Congress
I International Congress on Community Genetics.
2006 - 2006 Poster presentation: NS3 protein antigenic improvement for in vitro diagnosis of HCV.
Congress
Hepatología 2006.

Ad Hoc journal article review

Journal title (ISSN) Publisher
2023 - Current Small Wiley
2022 - Current Macromolecular chemistry and physics Wiley
2021 - Current Acta Biochimica Polonica (0001-527X)
2020 - Current Bionatura (1390-9355)

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018 - 2020 Molecular Biotechnology PhD programme, UdeC. Seminars and Conferences: Nanoparticles for biomedical applications. Electrospray and Electrospinning techniques. (Doctor of Philosophy) Universidad de Concepción Facultad de Ciencias Biológicas, Chile
2018 - 2020 Biomedical Engineering undergraduate programme, UdeC. Conferences and Laboratories: Matrix alternatives for nano and microencapsulation. (Bachelor) Universidad de Concepción Facultad de Ciencias Biológicas, Chile
2017 - 2018 Criminology undergraduate programme. Universidad Estatal de Sonora, Mexico: Fundamental Statistics. (Bachelor) Universidad Estatal de Sonora, Mexico

Evaluation committee

Activity description
Role
Institution / Organization Funding entity
2020 - 2020 Scientific referee for postdoc proposals: Estancias postdoctorales por Mexico. Conacyt, Mexico.
Evaluator
Consejo Nacional de Ciencia y Tecnología, Mexico
Distinctions

Award

2020 Winner of the Patent Contest Universidad de Concepción 2020
2020 Science with Impact Award 2020
Universidad de Concepción, Chile
2019 Winner of the Patent Contest Universidad de Concepción 2019
Universidad de Concepción, Chile
2011 Cuban Academy of Sciences Awards
Academia de Ciencias de Cuba, Cuba

Other distinction

2022 Seal of Excellence
Horizon Europe, Belgium
2019 Member of the National System of Researchers, Level I
Consejo Nacional de Ciencia y Tecnología, Mexico