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Inês Lourenço da Silva Delgado completed the PhD in Veterinary Sciences in 2022 by Faculdade de Medicina Veterinária da Universidade de Lisboa and MSc in Veterinary Medicine in 2011 by Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto. Is Assistant Professor in Faculdade de Medicina Veterinária da Universidade Lusófona - Centro Universitário de Lisboa since 2019, teaching courses on Parasitology and Parasitic Diseases. Works in the area(s) of Veterinary and Biological Sciences, at the interface of cellular and molecular biology and parasitology, with a main focus on tissue cyst forming apicomplexans. Published 11 peer-reviewed articles in journals. Has received 1 award in scientific photography and 1 award for best poster in a national conference. Since 2018, participates and/or participated as Principal investigator in 4 project(s) and Researcher in 4 project(s), mainly in the area of apicomplexan biology.
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Identification

Personal identification

Full name
Inês Lourenço da Silva Delgado

Citation names

  • L. S. Delgado, Inês
  • Delgado, Inês

Author identifiers

Ciência ID
1316-2129-8EB3
ORCID iD
0000-0002-7369-2883
Scopus Author Id
55295593100

Knowledge fields

  • Agrarian Sciences - Veterinary Sciences
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Advanced (C1) Intermediate (B1) Intermediate (B1)
French Intermediate (B1) Advanced (C1) Intermediate (B1) Intermediate (B1)
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2015/05/21 - 2022/04/29
Concluded
 PhD in Veterinary Sciences (Doutoramento)
Major in Biological and Biomedical Sciences
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
"Unraveling the replication process of Toxoplasma gondii through the Mob1 protein" (THESIS/DISSERTATION)
2021/11/09 - 2022/04/26
Ongoing
 I CURSO PÓS-GRADUADO ONE HEALTH - Saúde humana, Saúde animal, Saúde ambiental (Pós-Graduação)
Universidade de Lisboa Faculdade de Medicina, Portugal
2019/11/05 - 2019/11/09
Concluded
 Entry Level Bioinformatics (Outros)
Major in Bioinformática
Instituto Gulbenkian de Ciência, Portugal
2019/02/01 - 2019/07/31
Concluded
 Unidade curricular Bioinformática e Métodos Estatísticos do Mestrado Tecnologias Moleculares em Saúde (Outros)
Major in Bioinformática
Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
 16
2014/04/07 - 2014/04/10
Concluded
 COST Training School Proteome Bioinformatics (Outros)
Major in Bioinformática
Fundació Universitat Autónoma de Barcelona, Spain

Swiss Institute of Bioinformatics, Switzerland
2013/06/16 - 2013/07/05
Concluded
 Curso Ciencia de Animais de Laboratório - Categoria C (Outros)
Major in Experimentação Animal
Universidade do Porto, Portugal
 17
2013/02/25 - 2013/03/01
Concluded
 Introdução à estatística univariada e à linguagem R (Outros)
Major in Estatística
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2011/10/18 - 2011/10/21
Concluded
 FRAME Reduction Steering Committee Training School in Experimental Design and Statistics in Biomedical Experiments (Outros)
Major in Estatística
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2011
Concluded
 Mestrado Integrado em Medicina Veterinária (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"A seroprevalence study of antibodies against a novel canine norovirus in canine and human populations" (THESIS/DISSERTATION)
 14
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2021/09/01 - Current Assistant Professor (University Teacher) Universidade Lusófona de Humanidades e Tecnologias, Portugal
Universidade Lusófona de Humanidades e Tecnologias Faculdade de Medicina Veterinária, Portugal
2019/09/01 - 2021/08/31 Invited Assistant Professor (University Teacher) Universidade Lusófona de Humanidades e Tecnologias, Portugal
Universidade Lusófona de Humanidades e Tecnologias, Portugal

Others

Category
Host institution 		Employer
2015/05/01 - 2022/04/29 PhD in Veterinary Sciences, Biological and Biomedical specialization, with the thesis "Unraveling the replication process of Toxoplasma gondii through the Mob1 protein" Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2014/04/17 - 2015/04/14 Research assistant in the project "Mob1 protein: a critical factor in Toxoplasma gondii replication" (EXPL/CVT-EPI/1945/2013). Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
2013/05/15 - 2013/09/30 Research assistant Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2011/07/15 - 2013/04/30 Research assistant in the project "Ion and iron regulatory physiology in the marine lamprey (Petromyzon marinus). A parasitic feeder.¿ (PTDC/MAR/098035/2008) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2010/11/01 - 2011/03/31 Intern Universidade do Porto Faculdade de Farmácia, Portugal
Projects

Grant

Designation Funders
2023/05 - Current UNCOVERING ZOONOTIC Toxoplasma gondii GENETIC DIVERSITY AND ITS IMPLICATION ON TOXOPLASMOSIS PATHOGENESIS - AN ONE HEALTH APPROACH
Toxoplasma gondii GENETIC DIVERSITY
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Laboratório Associado para Ciência Animal e Veterinária (AL4AnimalS)
Ongoing
2023/01 - Current Finding the role of Tubulin Cofactor B in Toxoplasma gondii host cell invasion
TBCB
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Concluded
2022/11 - Current DeVPat - Detection of Vector-borne Protozoan and Bacterial Pathogens in Companion Animals
DeVPat
Principal investigator
Universidade Lusófona de Humanidades e Tecnologias Faculdade de Medicina Veterinária, Portugal
 Universidade Lusófona de Humanidades e Tecnologias Faculdade de Medicina Veterinária
Concluded
2021/01 - Current Targeting TLR2 for improved veterinary vaccines
PTDC/CVT-CVT/4599/2021
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2023/01 - 2023/12 Identification of the biological interacting partners of DP146L protein of African Swine Fever Virus
Projetos CIISA INOV 2022
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
2021/01/01 - 2021/10/31 Characterization of the T. gondii TBCB interactome
CIISA CONTSet20 - 12 (UID/CVT/00276/2019)
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Ongoing
2021/01/01 - 2021/10/31 Development of Feline Colon-Derived Organoid to study the sexual reproduction of Toxoplasma gondii
CIISA INOVSet20 - 05 (UID/CVT/00276/2019)
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
2020/01/01 - 2020/12/31 Characterization of the MOB1 interactome
CIISA CONT 10-2019
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Ongoing
2015/05 - 2019/04 Unraveling the replication process of Toxoplasma gondii through the Mob1 protein
SFRH/BD/101619/2014
 Fundação para a Ciência e a Tecnologia, I.P.
2014/03 - 2015/03 Mob1 protein: a critical factor in Toxoplasma gondii replication
Provided by PTCRIS: 134970
134970
Research Fellow
Fundação para a Ciência e a Tecnologia, I.P.
2013/05/01 - 2013/10/31 The invertebrate repertoire of nuclear receptors: evolutionary and endocrine disruption insights
PTDC/MAR/105199/2008
Research Fellow
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011/07/01 - 2013/04/30 Ion and iron regulatory physiology in the marine lamprey (Petromyzon marinus). A parasitic feeder
PTDC/MAR/098035/2008
Research Fellow
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference poster
  1. L. S. Delgado, Inês. "Modulating germinal centres via TLR2". Paper presented in 18th International Congress of Immunology, 2023.
  2. L. S. Delgado, Inês. "Assessing the role of Tubulin-binding cofactor B in the zoonotic parasite Toxoplasma gondii". Paper presented in Congresso sobre Medicina Comparativa e Translacional e Biotecnologia, 2023.
  3. L. S. Delgado, Inês. "MOB1 in Toxoplasma gondii - a player in the asexual and sexual phases of the parasite's life cycle". Paper presented in 2nd Meeting of the Associate Laboratory for Animal and Veterinary Sciences – AL4Animals, 2023.
  4. L. S. Delgado, Inês. Corresponding author: L. S. Delgado, Inês. "Caracterização molecular de Hepatozoon canis em Portugal". Paper presented in 10º Encontro de Formação da Ordem dos Médicos Veterinários – EFOMV, 2023.
  5. Sara Tudela Zúquete; Basto, Afonso P.. Corresponding author: Basto, Afonso P.. "Equipping non-mucosal dendritic cells to prime th1 cells with gut tropism by a combined TLR2/TLR4 activation". Paper presented in XLVIII Annual Meeting of the Portuguese Society for Immunology – SPI 48, 2023.
  6. L. S. Delgado, Inês. "The coccidian Toxoplasma gondii’s MOB1: an unexpected story.". Paper presented in CIISA Congress 2022, 2022.
  7. L. S. Delgado, Inês; Tavares, A; Samuel, F; Santos, D; Coelho, J; Basto, Afonso P.; Müller, J; et al. "Toxoplasma gondii MOB1 protein at the crossroad of cytokinesis and tissue homeostasis.". Paper presented in ApiCOWplexa 2012 – 6th International Meeting on Apicomplexa in Farm Animals, 2022.
  8. "Study of Mob1 in the apicomplexan Toxoplasma gondii: at the crossroads of asexual and sexual development". Paper presented in Cell Bio Virtual 2021 - ASCB|EMBO Meeting, 2021.
  9. "Characterization of the Tubulin-binding cofactor B in Toxoplasma gondii, a zoonotic parasite". Paper presented in Cell Bio Virtual 2021 - ASCB|EMBO Meeting, 2021.
  10. L. S. Delgado, Inês. "MOB1 of Toxoplasma gondii regulates cell division rate and tachyzoite-bradyzoite conversion during the parasite’s asexual cycle". Paper presented in Cell Bio 2020 Virtual - An Online ASCB|EMBO Meeting, 2020.
  11. L. S. Delgado, Inês. "Bioinformatic and experimental identification of a MEN/Hippo pathway in Toxoplasma gondii.". Paper presented in ApiCOWplexa 2019 – 5th International Meeting on Apicomplexa in Farm Animals, 2019.
  12. L. S. Delgado, Inês. "Establishing a skin immune alarm to prevent tick-borne apicomplexan parasite transmission". Paper presented in ApiCOWplexa 2019 – 5th International Meeting on Apicomplexa in Farm Animals, 2019.
  13. L. S. Delgado, Inês. "Do dendritic cell derived exosomes play a role in Toxoplasma gondii infection?". Paper presented in ApiCOWplexa 2019 – 5th International Meeting on Apicomplexa in Farm Animals, 2019.
  14. L. S. Delgado, Inês. "Evaluation of Cistus ladanifer L. effect on gastrointestinal parasites in lambs.". Paper presented in I Bioactive Natural Products Research Meeting 2019 (Bio.Natural Meeting 2019), 2019.
  15. L. S. Delgado, Inês. "Evaluating natural alternatives as hypothetical nutraceuticals against gastrointestinal parasites in lactating Goats". Paper presented in I Bioactive Natural Products Research Meeting 2019 (Bio.Natural Meeting 2019), 2019.
  16. L. S. Delgado, Inês. "The Toxoplasma gondii MOB1 protein is involved in the regulation of the parasite’s replication rate.". Paper presented in CIISA Congress 2018 - Exploring the boundaries of animal, veterinary and biomedical sciences, 2018.
  17. L. S. Delgado, Inês. "Toxoplasma gondii tubulin-binding cofactor B a polarity factor required for host cell invasion.". Paper presented in CIISA Congress 2018 - Exploring the boundaries of animal, veterinary and biomedical sciences, 2018.
  18. L. S. Delgado, Inês. "Decrypting a parasitic mystery: a genomic and transcriptomic study of Besnoitia besnoitii.". Paper presented in Toxo14 – The 14th biennial conference of the Toxoplasma gondii research community, 2017.
  19. Skariah, Sini; Mordue, Dana; Sultan, Ali. "Mob1, a key player in the replication of Toxoplasma gondii". Paper presented in EMBO Young Scientists' Forum 2016, 2016.
  20. L. S. Delgado, Inês. "Mob1, hippo pathway member, is critical for Toxoplasma gondii replication.". Paper presented in CQBday, 2016.
  21. L. S. Delgado, Inês. "Toxoplasma gondii Mob1 sub-cellular localization and assessment of its potential role in parasite replication". Paper presented in 7th European Congress on Protistology, 2015.
  22. L. S. Delgado, Inês. "Mob1 protein: a critical factor in Toxoplasma gondii replication". Paper presented in 3rd International Meeting on Apicomplexan Parasites in Farm Animals, 2015.
  23. L. S. Delgado, Inês. "Both seawater acclimation and environmental ammonia exposure lead to up-regulation of NKCC, CFTR and NKA in the gills of the climbing perch". Paper presented in 10th International Congress on the Biology of Fish, 2012.
  24. L. S. Delgado, Inês. "Identification of a branchial organic anion transport protein (OATP) Slc1c1 in the lamprey ammocoete larvae (Petromyzon marinus L.)". Paper presented in Society for Experimental Biology, 2012.
  25. L. S. Delgado, Inês. "Seroprevalence of a novel Canine Norovirus in pet dogs". Paper presented in IV Encontro de Jovens Investigadores da Universidade do Porto, 2011.
  26. L. S. Delgado, Inês. "Zoonose por Norovirus Canino: seroprevalência em veterinários e população geral". Paper presented in VI Congresso Hospital Veterinário Montenegro, 2011.
Journal article
  1. Inês L. S. Delgado; João Gonçalves; Rita Fernandes; Sara Zúquete; Afonso P. Basto; Alexandre Leitão; Helena Soares; Sofia Nolasco. "Balancing Act: Tubulin Glutamylation and Microtubule Dynamics in Toxoplasma gondii". Microorganisms (2024): https://doi.org/10.3390/microorganisms12030488.
    10.3390/microorganisms12030488
  2. Catarina Anastácio; Ricardo Bexiga; Sofia Nolasco; Sara Zúquete; Inês L. S. Delgado; Telmo Nunes; Alexandre Leitão. "Impact of Endemic Besnoitiosis on the Performance of a Dairy Cattle Herd". Animals 12 10 (2022): 1291-1291. https://doi.org/10.3390/ani12101291.
    10.3390/ani12101291
  3. Inês L. S. Delgado; Sara Zúquete; Dulce Santos; Afonso P. Basto; Alexandre Leitão; Sofia Nolasco. "The Apicomplexan Parasite Toxoplasma gondii". Encyclopedia (2022): https://doi.org/10.3390/encyclopedia2010012.
    10.3390/encyclopedia2010012
  4. Inês L. S. Delgado; Alexandra Tavares; Samuel Francisco; Dulce Santos; João Coelho; Afonso P. Basto; Sara Zúquete; et al. "Characterization of a MOB1 Homolog in the Apicomplexan Parasite Toxoplasma gondii". Biology (2021): https://doi.org/10.3390/biology10121233.
    10.3390/biology10121233
  5. Inês Delgado; Bruno Carmona; Sofia Nolasco; Dulce Santos; Alexandre Leitão; Helena Soares. "MOB: Pivotal Conserved Proteins in Cytokinesis, Cell Architecture and Tissue Homeostasis". Biology (2020): https://www.mdpi.com/2079-7737/9/12/413.
    10.3390/biology9120413
  6. Lopes-Marques, Mónica; Delgado, Inês L. S.; Ruivo, Raquel; Torres, Yan; Sainath, Sri Bhashyam; Rocha, Eduardo; Cunha, Isabel; Santos, Miguel M.; Castro, L. Filipe C.. "The Origin and Diversity of Cpt1 Genes in Vertebrate Species". PLOS ONE 10 9 (2015): e0138447. http://dx.doi.org/10.1371/journal.pone.0138447.
    10.1371/journal.pone.0138447
  7. Lopes-Marques, Mónica; Ruivo, Raquel; Delgado, Inês; Wilson, Jonathan M.; Aluru, Neelakanteswar; Castro, L. Filipe C.. "Basal Gnathostomes Provide Unique Insights into the Evolution of Vitamin B12 Binders". Genome Biology and Evolution 7 2 (2014): 457-464. http://dx.doi.org/10.1093/gbe/evu289.
    10.1093/gbe/evu289
  8. Mesquita JR; Delgado I; Costantini V; Heenemann K; Vahlenkamp TW; Vinjé J; Nascimento MS. "Seroprevalence of canine norovirus in 14 European countries.". (2014): http://europepmc.org/abstract/med/24671552.
    10.1128/CVI.00048-14
  9. Wilson, J. M.; Moreira-Silva, J.; Delgado, I. L. S.; Ebanks, S. C.; Vijayan, M. M.; Coimbra, J.; Grosell, M.. "Mechanisms of transepithelial ammonia excretion and luminal alkalinization in the gut of an intestinal air-breathing fish, Misgurnus anguilliacaudatus". Journal of Experimental Biology 216 4 (2012): 623-632. http://dx.doi.org/10.1242/jeb.074401.
    10.1242/jeb.074401
  10. Ip, Yuen K.; Loong, Ai M.; Kuah, Jie S.; Sim, Eugene W. L.; Chen, Xiu L.; Wong, Wai P.; Lam, Siew H.; et al. "Roles of three branchial Na+-K+-ATPase a-subunit isoforms in freshwater adaptation, seawater acclimation, and active ammonia excretion in Anabas testudineus". American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 303 1 (2012): R112-R125. http://dx.doi.org/10.1152/ajpregu.00618.2011.
    10.1152/ajpregu.00618.2011
  11. Ip, Yuen K.; Wilson, Jonathan M.; Loong, Ai M.; Chen, Xiu L.; Wong, Wai P.; Delgado, Inês L. S.; Lam, Siew H.; Chew, Shit F.. "Cystic fibrosis transmembrane conductance regulator in the gills of the climbing perch, Anabas testudineus, is involved in both hypoosmotic regulation during seawater acclimation and active ammonia excretion during ammonia exposure". Journal of Comparative Physiology B 182 6 (2012): 793-812. http://dx.doi.org/10.1007/s00360-012-0664-9.
    10.1007/s00360-012-0664-9
Preprint
  1. Inês L.S. Delgado; João Gonçalves; Rita Fernandes; Sara Zúquete; Afonso P. Basto; Alexandre Leitão; Helena Soares; Sofia Nolasco. "Balancing Act: Tubulin Glutamylation and Microtubule Dynamics in Toxoplasma gondii". 2024. https://doi.org/10.20944/preprints202401.0287.v1.
    10.20944/preprints202401.0287.v1
Thesis / Dissertation
  1. Delgado, Inês. "A seroprevalence study of antibodies against a novel canine norovirus in canine and human populations". Master, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 2011.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/04/07 Estudo do interactoma da proteína MOB1 de Toxoplasma gondii usando ferramentas bioinformáticas e tecnologia BioID 9º Encontro de Formação da Ordem dos Médicos Veterinarios
Ordem dos Médicos Veterinarios (Lisboa, Portugal)
2018/11/16 Tubulin Cofactor B: a key player in Toxoplasma gondii host cell invasion CIISA Congress 2018 - Exploring the boundaries of animal, veterinary and biomedical sciences
CIISA (Lisboa, Portugal)
2017/10/13 A component of the core kinase module of MEN and Hippo pathways, MOB1 is a critical factor in Toxoplasma gondii replication ApiCOWplexa 2017 – 4th International Meeting on Apicomplexa in Farm Animals
(Madrid, Spain)
2017/06/01 Role of the Mob1 protein in Toxoplasma gondii replication Toxo14 – The 14th biennial conference of the Toxoplasma gondii research community
IGC (Tomar, Portugal)
2015/07/10 Mob1: at the crossroad between morphogenesis, cytokinesis and cell proliferation control in unicellular organisms Conference on Ciliate Molecular Biology
International School of Advanced Studies, University of Camerino (Camerino, Italy)
2013/05/06 Lamprey branchial ion regulation. Same old story? Frontiers in Tropical Aquatic Physiology – A tribute to David Randall
(Manaus, Brazil)

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019/09/01 - Current Parasitology Medicina Veterinária (Mestrado integrado) Universidade Lusófona de Humanidades e Tecnologias, Portugal
2019/09/01 - Current Parasitic Diseases of Companion Animals Medicina Veterinária (Mestrado integrado) Universidade Lusófona de Humanidades e Tecnologias, Portugal
Distinctions

Award

2023 Best Poster Prize - II FMVet Research Meetings
Universidade Lusófona de Humanidades e Tecnologias Faculdade de Medicina Veterinária, Portugal
2019 1st Prize of Scientific Photography Contest by Bolseiros CIISA
Bolseiros CIISA, AEFMV-UL, Portugal