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By training, I am a Particle Physicist that fell in love with Biological Physics shortly after graduating. I did my PhD in both the Musa Mhlanga and Christophe Zimmer laboratories, carrying out research between IMM (Portugal), Institut Pasteur (France), CSIR (South Africa) and Andor Technology (UK and USA). During this time, I entered the field of Super-Resolution Microscopy, developing technologies that enable imaging of cellular and viral structures at unprecedented resolution. During my PhD and postdoc, I applied the methods I developed to study Cell Signalling, T-cell Immunology and Viral Infection. In 2013 I established my first research group at UCL, with a dual emphasis on Developing new Imaging Technologies and Cell Biology research. In 2017, I was further invited to extend my group to the Francis Crick Institute, where I established a second small laboratory. In 2019 I was promoted to full Professor at UCL. My technological developments are widely disseminated to the Cell Biology and Biomedical research community. My algorithms QuickPALM, NanoJ, SRRF and SQUIRREL are among the most used and cited analytical methods in the Super-Resolution Microscopy field. My core philosophy has been to make my research reproducible, transparent and open-source. An updated view of my scientific track record can be seen at https://henriqueslab.org.
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Identification

Personal identification

Full name
Ricardo José dos Santos Duarte Vieira Henriques

Citation names

  • Henriques, Ricardo

Author identifiers

Ciência ID
1318-A3CF-7610
ORCID iD
0000-0002-2043-5234
Google Scholar ID
-peQ4ZsAAAAJ

Email addresses

  • r.henriques@ucl.ac.uk (Professional)
  • rjhenriques@igc.gulbenkian.pt (Professional)

Telephones

Mobile phone
  • (+351) 934420536 (Professional)

Addresses

  • Instituto Gulbenkian de Ciência, Rua da Quinta Grande, 6, P-2780-156, Oeiras, Lisboa, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2008/09/01 - 2011/09/01
Concluded
 Structural Biology and Biophysics (Doutoramento)
Instituto de Medicina Molecular, Portugal
"Beyond Rayleigh's limit: achieving real-time super-resolution fluorescence microscopy" (THESIS/DISSERTATION)
 Honra e Louvor
Affiliation

Science

Category
Host institution 		Employer
2020/09/01 - Current Principal Investigator (Research) Instituto Gulbenkian de Ciência, Portugal
Instituto Gulbenkian de Ciência, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2020/09/01 - 2025/08/31 Visiting Professor (University Teacher) MRC Laboratory for Molecular Cell Biology, United Kingdom
University College London Division of Biosciences, United Kingdom
2019/10/01 - 2020/08/31 Full Professor (University Teacher) University College London, United Kingdom
University College London, United Kingdom
(...)
2013/09/01 - 2019/10/01 Associate Professor (University Teacher) University College London, United Kingdom
Projects

Grant

Designation Funders
2020/07 - 2028/09 Optical Biology
218530/Z/19/Z
 Wellcome Trust
2021/07 - 2026/06 Enabling Live-Cell 4D Super-Resolution Microscopy Guided by Artificial Intelligence
101001332
 European Research Council
2022/01 - 2025/01 Regulation of de Novo Centriole Biogenesis by the Actin Network
Provided by PTCRIS: PTDC/BIA-CEL/4202/2021
 Fundação para a Ciência e a Tecnologia
2021/03 - 2024/02 Investigação dos mecanismos subjacentes à interacção da imunidade autónoma com a divisão e persistência intracelular de Staphylococcus aureus.
Provided by PTCRIS: PTDC/BIA-MIC/2422/2020
 Fundação para a Ciência e a Tecnologia
2018/09 - 2022/09 Content Aware AI Driven Driven Super Resolution Microscopy
BB/S507532/1
 Biotechnology and Biological Sciences Research Council
2020/06 - 2021/06 Benchtop, turnkey super-resolution microscopy for biology, biophysics and biotechnology
BB/T01749X/1
 Biotechnology and Biological Sciences Research Council
2019/01 - 2020/02 Democratising Live-Cell Adaptive Super-Resolution Microscopy based on SRRF
BB/R021805/1
 Biotechnology and Biological Sciences Research Council
2013/07 - 2016/12 Imagiologia da estrutura e dinâmica de moléculas e complexos em organismos vivos
Provided by PTCRIS: RECI/BEX-BCM/0083/2012
 Fundação para a Ciência e a Tecnologia
2008/01 - 2011/12 Identificação e caracterização dos supercomplexos das cadeias respiratórias aeróbias das bactérias Escherichia coli e Bacillus subtilis
Provided by PTCRIS: PTDC/SAU-GMG/115652/2009
 Fundação para a Ciência e a Tecnologia
2008/01 - 2011/12 Identificação e caracterização dos supercomplexos das cadeias respiratórias aeróbias das bactérias Escherichia coli e Bacillus subtilis
Provided by PTCRIS: PTDC/BIA-PRO/67105/2006
 Fundação para a Ciência e a Tecnologia
2010/01 - 2011/10 SPATIO-TEMPORAL TRACKING OF GENE EXPRESSION IN LIVING CELLS VIA SUPER-RESOLUTION MICROSCOPY
Provided by PTCRIS: SFRH/BD/63680/2009
 Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2016/12 - 2021/12 Understanding cellular organisation: from archaea to eukaryotes
203276/Z/16/Z
Researcher
Wellcome Trust
Ongoing
2017/12 - 2018/12 An accessible framework to achieve multi-dimensional live-cell super-resolution high-content screening
BB/P027431/1
Principal investigator
Biotechnology and Biological Sciences Research Council
Concluded
2016/01 - 2018/12 Super-Beacons and Beacon-STORM: a new generation of small tunable photoswitching probes and Super-Resolution approaches.
BB/M022374/1
Principal investigator
Biotechnology and Biological Sciences Research Council
Concluded
2017/05 - 2018/05 Enabling Live-Cell Super Resolution Imaging Through Lattice Light Sheet Microscopy
BB/R000697/1
Researcher
Biotechnology and Biological Sciences Research Council
Concluded
2013/07 - 2016/06 Imaging the structure and dynamics of molecules and complexes in living organisms
Provided by PTCRIS: 124825
Researcher
Instituto Gulbenkian de Ciência
2011/01 - 2014/06 Super-resolution Imaging of Gene Expression & Nuclear Architecture
Provided by PTCRIS: 115652
Researcher
Instituto de Medicina Molecular
2008/01 - 2011/12 Identification and characterization of the supercomplexes from the bacterial aerobic respiratory chain of Escherichia coli and Bacillus subtilis
Provided by PTCRIS: 67105
Technical development
Instituto de Medicina Molecular
Concluded
2007/07 - 2010/07 Effects of inflammation on bone and cartilage: collagen pattern and biomechanical properties
Provided by PTCRIS: 65992
Technical development
Instituto de Medicina Molecular
Concluded
Outputs

Publications

Book
  1. Ann Wheeler; Ricardo Henriques. Standard and Super-Resolution Bioimaging Data Analysis. John Wiley {\&. 2017.
    10.1002/9781119096948
Journal article
  1. Estibaliz Gómez-de-Mariscal; Mario Del Rosario; Joanna W. Pylvänäinen; Guillaume Jacquemet; Ricardo Henriques. "Harnessing artificial intelligence to reduce phototoxicity in live imaging". Journal of Cell Science (2024): https://doi.org/10.1242/jcs.261545.
    10.1242/jcs.261545
  2. Ricardo Henriques; Christophe Leterrier; Aubrey Weigel. "Decoding life's inner workings: advances in quantitative bioimaging". Open Biology (2023): https://doi.org/10.1098/rsob.230329.
    10.1098/rsob.230329
  3. Pylvänäinen JW; Laine RF; Saraiva BMS; Ghimire S; Follain G; Henriques R; Jacquemet G. "Fast4DReg - fast registration of 4D microscopy datasets.". Journal of cell science (2023): http://europepmc.org/abstract/med/36727532.
    10.1242/jcs.260728
  4. Aristova D; Selin R; Heil HS; Kosach V; Slominsky Y; Yarmoluk S; Pekhnyo V; et al. "Trimethine Cyanine Dyes as NA-Sensitive Probes for Visualization of Cell Compartments in Fluorescence Microscopy.". ACS omega (2022): http://europepmc.org/abstract/med/36591208.
    10.1021/acsomega.2c05231
  5. Etienne Boulter; Julien Colombelli; Ricardo Henriques; Chloé C. Féral. "The LEGO® brick road to open science and biotechnology". Trends in Biotechnology (2022): https://doi.org/10.1016/j.tibtech.2022.02.003.
    10.1016/j.tibtech.2022.02.003
  6. Spahn C; Gómez-de-Mariscal E; Laine RF; Pereira PM; von Chamier L; Conduit M; Pinho MG; et al. "DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches.". Communications biology (2022): http://europepmc.org/abstract/med/35810255.
    10.1038/s42003-022-03634-z
  7. Afonso Mendes; Hannah S. Heil; Simao Coelho; Christophe Leterrier; Ricardo Henriques. "Mapping molecular complexes with super-resolution microscopy and single-particle analysis". Open Biology (2022): https://doi.org/10.1098/rsob.220079.
    10.1098/rsob.220079
  8. Tomaz D; Pereira PM; Guerra N; Dyson J; Gould K; Henriques R. "Nanoscale Colocalization of NK Cell Activating and Inhibitory Receptors Controls Signal Integration.". Frontiers in immunology (2022): http://europepmc.org/abstract/med/35720315.
    10.3389/fimmu.2022.868496
  9. Korovesi AG; Morgado L; Fumasoni M; Henriques R; Heil HS; Del Rosario M. "Expansion Microscopy on Saccharomyces cerevisiae.". microPublication biology (2022): http://europepmc.org/abstract/med/35647499.
    10.17912/micropub.biology.000566
  10. Lena Harker-Kirschneck; Anne E. Hafner; Tina Yao; Christian Vanhille-Campos; Xiuyun Jiang; Andre Pulschen; Fredrik Hurtig; et al. "Physical mechanisms of ESCRT-III–driven cell division". Proceedings of the National Academy of Sciences (2022): https://doi.org/10.1073/pnas.2107763119.
    10.1073/pnas.2107763119
  11. Kevin D. Whitley; Calum Jukes; Nicholas Tregidgo; Eleni Karinou; Pedro Almada; Yann Cesbron; Ricardo Henriques; Cees Dekker; Séamus Holden. "FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in Bacillus subtilis cell division". Nature Communications (2021): https://doi.org/10.1038/s41467-021-22526-0.
    10.1038/s41467-021-22526-0
  12. Mario Del Rosario; Hannah S. Heil; Afonso Mendes; Vittorio Saggiomo; Ricardo Henriques. "The Field Guide to 3D Printing in Optical Microscopy for Life Sciences". Advanced Biology (2021): https://doi.org/10.1002/adbi.202100994.
    10.1002/adbi.202100994
  13. Laine RF; Arganda-Carreras I; Henriques R; Jacquemet G. "Avoiding a replication crisis in deep-learning-based bioimage analysis.". Nature methods (2021): http://europepmc.org/abstract/med/34608322.
    10.1038/s41592-021-01284-3
  14. Bruno M. Saraiva; Ludwig Krippahl; Sérgio R. Filipe; Ricardo Henriques; Mariana G. Pinho. "eHooke: A tool for automated image analysis of spherical bacteria based on cell cycle progression". Biological Imaging (2021): 1-25. https://doi.org/10.1017/S2633903X21000027.
    10.1017/S2633903X21000027
  15. von Chamier L; Laine RF; Jukkala J; Spahn C; Krentzel D; Nehme E; Lerche M; et al. "Democratising deep learning for microscopy with ZeroCostDL4Mic.". Nature communications (2021): http://europepmc.org/abstract/med/33859193.
    10.1038/s41467-021-22518-0
  16. Emma Touizer; Christian Sieben; Ricardo Henriques; Mark Marsh; Romain F. Laine. "Application of Super-Resolution and Advanced Quantitative Microscopy to the Spatio-Temporal Analysis of Influenza Virus Replication". Viruses (2021): https://doi.org/10.3390/v13020233.
    10.3390/v13020233
  17. Yue Yuan; Caron A. Jacobs; Isabel Llorente Garcia; Pedro M. Pereira; Scott P. Lawrence; Romain F. Laine; Mark Marsh; Ricardo Henriques. "Single-Molecule Super-Resolution Imaging of T-Cell Plasma Membrane CD4 Redistribution upon HIV-1 Binding". Viruses 13 1 (2021): 142-142. https://doi.org/10.3390/v13010142.
    10.3390/v13010142
  18. Spark A; Kitching A; Esteban-Ferrer D; Handa A; Carr AR; Needham LM; Ponjavic A; et al. "vLUME: 3D virtual reality for single-molecule localization microscopy.". Nature methods (2020): http://europepmc.org/abstract/med/33046895.
    10.1038/s41592-020-0962-1
  19. Henriques, Ricardo. "Closed mitosis requires local disassembly of the nuclear envelope". Nature 585 7823 (2020): 119-123.
    10.1038/s41586-020-2648-3
  20. Tarrason Risa G; Hurtig F; Bray S; Hafner AE; Harker-Kirschneck L; Faull P; Davis C; et al. "The proteasome controls ESCRT-III-mediated cell division in an archaeon.". Science (New York, N.Y.) (2020): http://europepmc.org/abstract/med/32764038.
    10.1126/science.aaz2532
  21. Guillaume Jacquemet; Alexandre F. Carisey; Hellyeh Hamidi; Ricardo Henriques; Christophe Leterrier. "The cell biologist's guide to super-resolution microscopy". Journal of Cell Science (2020): https://doi.org/10.1242/jcs.240713.
    10.1242/jcs.240713
  22. Pulschen AA; Mutavchiev DR; Culley S; Sebastian KN; Roubinet J; Roubinet M; Risa GT; et al. "Live Imaging of a Hyperthermophilic Archaeon Reveals Distinct Roles for Two ESCRT-III Homologs in Ensuring a Robust and Symmetric Division.". Current biology : CB (2020): http://europepmc.org/abstract/med/32502411.
    10.1016/j.cub.2020.05.021
  23. Stubb A; Laine RF; Miihkinen M; Hamidi H; Guzmán C; Henriques R; Jacquemet G; Ivaska J. "Fluctuation-Based Super-Resolution Traction Force Microscopy.". Nano letters (2020): http://europepmc.org/abstract/med/32142297.
    10.1021/acs.nanolett.9b04083
  24. Christopher Bricogne; Michael Fine; Pedro M. Pereira; Julia Sung; Maha Tijani; Youxue Wang; Ricardo Henriques; Mary K. Collins; Donald W. Hilgemann. "TMEM16F activation by Ca2+ triggers plasma membrane expansion and directs PD-1 trafficking". Scientific Reports 9 1 (2019): https://doi.org/10.1038/s41598-018-37056-x.
    10.1038/s41598-019-43808-0
  25. Thevathasan JV; Kahnwald M; Cieslinski K; Hoess P; Peneti SK; Reitberger M; Heid D; et al. "Publisher Correction: Nuclear pores as versatile reference standards for quantitative superresolution microscopy.". Nature methods (2019): http://europepmc.org/abstract/med/31653976.
    10.1038/s41592-019-0659-5
  26. Robert D. M. Gray; David Albrecht; Corina Beerli; Moona Huttunen; Gary H. Cohen; Ian J. White; Jemima J. Burden; Ricardo Henriques; Jason Mercer. "Nanoscale polarization of the entry fusion complex of vaccinia virus drives efficient fusion". Nature Microbiology 4 10 (2019): 1636-1644. https://doi.org/10.1038/s41564-019-0488-4.
    10.1038/s41564-019-0488-4
  27. Henriques, Ricardo. "Nuclear pores as versatile reference standards for quantitative superresolution microscopy". Nature Methods (2019): http://dx.doi.org/10.1038/s41592-019-0574-9.
    10.1038/s41592-019-0574-9
  28. Patel L; Gustafsson N; Lin Y; Ober R; Henriques R; Cohen E. "A HIDDEN MARKOV MODEL APPROACH TO CHARACTERIZING THE PHOTO-SWITCHING BEHAVIOR OF FLUOROPHORES.". The annals of applied statistics (2019): http://europepmc.org/abstract/med/31933716.
    10.1214/19-aoas1240
  29. Sage D; Pham TA; Babcock H; Lukes T; Pengo T; Chao J; Velmurugan R; et al. "Publisher Correction: Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software.". Nature methods (2019): http://europepmc.org/abstract/med/31097821.
    10.1038/s41592-019-0453-4
  30. Sage D; Pham TA; Babcock H; Lukes T; Pengo T; Chao J; Velmurugan R; et al. "Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software.". Nature methods (2019): http://europepmc.org/abstract/med/30962624.
    10.1038/s41592-019-0364-4
  31. Pereira PM; Albrecht D; Culley S; Jacobs C; Marsh M; Mercer J; Henriques R. "Fix Your Membrane Receptor Imaging: Actin Cytoskeleton and CD4 Membrane Organization Disruption by Chemical Fixation.". Frontiers in immunology (2019): http://europepmc.org/abstract/med/31024536.
    10.3389/fimmu.2019.00675
  32. Felix Weihs; Katarzyna Wacnik; Robert D. Turner; Siân Culley; Ricardo Henriques; Simon J. Foster. "Heterogeneous localisation of membrane proteins in Staphylococcus aureus". Scientific Reports 8 1 (2018): https://doi.org/10.1038/s41598-018-21750-x.
    10.1038/s41598-018-21750-x
  33. Weigert M; Schmidt U; Boothe T; Müller A; Dibrov A; Jain A; Wilhelm B; et al. "Content-aware image restoration: pushing the limits of fluorescence microscopy.". Nature methods (2018): http://europepmc.org/abstract/med/30478326.
    10.1038/s41592-018-0216-7
  34. Siân Culley; Kalina L. Tosheva; Pedro Matos Pereira; Ricardo Henriques. "SRRF: Universal live-cell super-resolution microscopy". The International Journal of Biochemistry & Cell Biology 101 (2018): 74-79. https://doi.org/10.1016/j.biocel.2018.05.014.
    10.1016/j.biocel.2018.05.014
  35. Siân Culley; David Albrecht; Caron Jacobs; Pedro Matos Pereira; Christophe Leterrier; Jason Mercer; Ricardo Henriques. "Quantitative mapping and minimization of super-resolution optical imaging artifacts". Nature Methods (2018): https://doi.org/10.1038/nmeth.4605.
    10.1101/158279
  36. Dix CL; Matthews HK; Uroz M; McLaren S; Wolf L; Heatley N; Win Z; et al. "The Role of Mitotic Cell-Substrate Adhesion Re-modeling in Animal Cell Division.". Developmental cell (2018): http://europepmc.org/abstract/med/29634933.
    10.1016/j.devcel.2018.03.009
  37. Robert D. M. Gray; Jason Mercer; Ricardo Henriques. "Open-source Single-particle Analysis for Super-resolution Microscopy with VirusMapper". Journal of Visualized Experiments 122 (2017): https://doi.org/10.3791%2F55471.
    10.3791/55471
  38. Nils Gustafsson; Siân Culley; George Ashdown; Dylan M. Owen; Pedro Matos Pereira; Ricardo Henriques. "Fast live-cell conventional fluorophore nanoscopy with ImageJ through super-resolution radial fluctuations". Nature Communications 7 (2016): 12471-12471. https://doi.org/10.1038/ncomms12471.
    10.1038/ncomms12471
  39. Barbara Clough; Eric Y Denkers; Joseph D. Wright; Pedro M. Pereira; Elizabeth M. Hirst; Ashleigh C. Johnston; Ricardo Henriques; Eva-Maria Frickel. "K63-Linked Ubiquitination Targets Toxoplasma gondii for Endo-lysosomal Destruction in IFN¿-Stimulated Human Cells". PLOS Pathogens 12 11 (2016): e1006027-e1006027. http://dx.doi.org/10.1371/journal.ppat.1006027.
    10.1371/journal.ppat.1006027
  40. Joana G. Silva; Nuno P. Martins; Ricardo Henriques; Helena Soares. "HIV-1 Nef Impairs the Formation of Calcium Membrane Territories Controlling the Signaling Nanoarchitecture at the Immunological Synapse". The Journal of Immunology 197 10 (2016): 4042-4052. https://doi.org/10.4049/jimmunol.1601132.
    10.4049/jimmunol.1601132
  41. Siân Culley; Greg Towers; David Selwood; Ricardo Henriques; Joe Grove. "Infection Counter: Automated Quantification of in Vitro Virus Replication by Fluorescence Microscopy". Viruses 8 12 (2016): 201-201. https://doi.org/10.3390/v8070201.
    10.3390/v8070201
  42. Gray RD; Beerli C; Pereira PM; Scherer KM; Samolej J; Bleck CK; Mercer J; Henriques R. "VirusMapper: open-source nanoscale mapping of viral architecture through super-resolution microscopy.". (2016): http://europepmc.org/abstract/med/27374400.
    10.1038/srep29132
  43. Sirianni A; Krokowski S; Lobato-Márquez D; Buranyi S; Pfanzelter J; Galea D; Willis A; et al. "Mitochondria mediate septin cage assembly to promote autophagy of Shigella.". (2016): http://europepmc.org/abstract/med/27259462.
  44. Scholefield J; Henriques R; Savulescu AF; Fontan E; Boucharlat A; Laplantine E; Smahi A; et al. "Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti.". (2016): http://europepmc.org/abstract/med/27586688.
    10.1038/ncomms12629
  45. Almada P; Culley S; Henriques R. "PALM and STORM: Into large fields and high-throughput microscopy with sCMOS detectors.". (2015): http://europepmc.org/abstract/med/26079924.
    10.1016/j.ymeth.2015.06.004
  46. Pereira PM; Almada P; Henriques R. "High-content 3D multicolor super-resolution localization microscopy.". (2015): http://europepmc.org/abstract/med/25640426.
    10.1016/bs.mcb.2014.10.004
  47. Tarantino N; Tinevez JY; Crowell EF; Boisson B; Henriques R; Mhlanga M; Agou F; Israël A; Laplantine E. "TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO-IKK supramolecular structures.". (2014): http://europepmc.org/abstract/med/24446482.
    10.1083/jcb.201307172
  48. Soares H; Henriques R; Sachse M; Ventimiglia L; Alonso MA; Zimmer C; Thoulouze MI; Alcover A. "Regulated vesicle fusion generates signaling nanoterritories that control T cell activation at the immunological synapse.". (2013): http://europepmc.org/abstract/med/24101378.
    10.1084/jem.20130150
  49. Ehsani S; Santos JC; Rodrigues CD; Henriques R; Audry L; Zimmer C; Sansonetti P; Tran Van Nhieu G; Enninga J. "Hierarchies of host factor dynamics at the entry site of Shigella flexneri during host cell invasion.". (2012): http://europepmc.org/abstract/med/22526677.
    10.1128/IAI.06391-11
  50. Lelek M; Di Nunzio F; Henriques R; Charneau P; Arhel N; Zimmer C. "Superresolution imaging of HIV in infected cells with FlAsH-PALM.". (2012): http://europepmc.org/abstract/med/22586087.
    10.1073/pnas.1013267109
  51. Herbert S; Henriques R. "Enhanced epifluorescence microscopy by uniform and intensity optimized illumination.". (2012): http://europepmc.org/abstract/med/22392634.
    10.1002/cyto.a.21177
  52. Gomes-Santos CS; Itoe MA; Afonso C; Henriques R; Gardner R; Sepúlveda N; Simões PD; et al. "Highly dynamic host actin reorganization around developing Plasmodium inside hepatocytes.". (2012): http://europepmc.org/abstract/med/22238609.
    10.1371/journal.pone.0029408
  53. Henriques, Ricardo. "Single-molecule localization super-resolution microscopy: deeper and faster". Microscopy and microanalysis 18 6 (2012): 1419-1429.
    10.1017/s1431927612013347
  54. Henriques R; Griffiths C; Hesper Rego E; Mhlanga MM. "PALM and STORM: unlocking live-cell super-resolution.". (2011): http://europepmc.org/abstract/med/21254001.
    10.1002/bip.21586
  55. Henriques R; Lelek M; Fornasiero EF; Valtorta F; Zimmer C; Mhlanga MM. "QuickPALM: 3D real-time photoactivation nanoscopy image processing in ImageJ.". (2010): http://europepmc.org/abstract/med/20431545.
    10.1038/nmeth0510-339
  56. Henriques R; Mhlanga MM. "PALM and STORM: what hides beyond the Rayleigh limit?". (2009): http://europepmc.org/abstract/med/19548237.
    10.1002/biot.200900024
  57. Henriques, Ricardo. "Editorial: Imaging host-pathogen interactions". Biotechnology Journal (2009): http://dx.doi.org/10.1002/biot.200900129.
    10.1002/biot.200900129
  58. Henriques, Ricardo. "Chronic arthritis directly induces quantitative and qualitative bone disturbances leading to compromised biomechanical properties.". Clinical and experimental rheumatology (2009):
  59. Rino J; Braga J; Henriques R; Carmo-Fonseca M. "Frontiers in fluorescence microscopy.". (2009): http://europepmc.org/abstract/med/19247949.
    10.1387/ijdb.072351jr
  60. Barreiro LB; Henriques R; Mhlanga MM. "High-throughput SNP genotyping: combining tag SNPs and molecular beacons.". (2009): http://europepmc.org/abstract/med/19768600.
    10.1007/978-1-60327-411-1_17
Preprint
  1. Iván Hidalgo-Cenalmor; Joanna W Pylvänäinen; Mariana G Ferreira; Craig T Russell; Ignacio Arganda-Carreras; Guillaume Jacquemet; Ricardo Henriques; Estibaliz Gómez-de-Mariscal. "DL4MicEverywhere: Deep learning for microscopy made flexible, shareable, and reproducible". 2023. https://doi.org/10.1101/2023.11.19.567606.
    10.1101/2023.11.19.567606
  2. Christoph Spahn; Stuart Middlemiss; Estibaliz Gómez-de-Mariscal; Ricardo Henriques; Helge B. Bode; Séamus Holden; Mike Heilemann. "Transertion and cell geometry organize theEscherichia colinucleoid during rapid growth". 2023. https://doi.org/10.1101/2023.10.16.562172.
    10.1101/2023.10.16.562172
  3. Bruno M. Saraiva; Inês M. Cunha; António D. Brito; Gautier Follain; Raquel Portela; Robert Haase; Pedro M. Pereira; Guillaume Jacquemet; Ricardo Henriques. "NanoPyx: super-fast bioimage analysis powered by adaptive machine learning". 2023. https://doi.org/10.1101/2023.08.13.553080.
    10.1101/2023.08.13.553080
  4. Daniel Krentzel; Matouš Elphick; Marie-Charlotte Domart; Christopher J. Peddie; Romain F. Laine; Ricardo Henriques; Lucy M. Collinson; Martin L. Jones. "CLEM-Reg: An automated point cloud based registration algorithm for correlative light and volume electron microscopy". 2023. https://doi.org/10.1101/2023.05.11.540445.
    10.1101/2023.05.11.540445
  5. Pylvänäinen JW; Laine RF; Saraiva BM; Ghimire S; Follain G; Henriques R; Jacquemet G. "Fast4DReg: Fast registration of 4D microscopy datasets". 2022. http://europepmc.org/abstract/PPR/PPR534863.
    10.1101/2022.08.22.504744
  6. Korovesi AG; Morgado L; Fumasoni M; Henriques R; Heil H; Del Rosario M. "Expansion Microscopy on Saccharomyces cerevisiae". 2022. http://europepmc.org/abstract/PPR/PPR466677.
    10.20944/preprints202203.0146.v1
  7. Ouyang W; Beuttenmueller F; Gómez-de-Mariscal E; Pape C; Burke T; Garcia-López-de-Haro C; Russell C; et al. "BioImage Model Zoo: A Community-Driven Resource for Accessible Deep Learning in BioImage Analysis". 2022. http://europepmc.org/abstract/PPR/PPR504634.
    10.1101/2022.06.07.495102
  8. Laine RF; Heil HS; Coelho S; Nixon-Abell J; Jimenez A; Galgani T; Stubb A; et al. "High-fidelity 3D live-cell nanoscopy through data-driven enhanced super-resolution radial fluctuation". 2022. http://europepmc.org/abstract/PPR/PPR479048.
    10.1101/2022.04.07.487490
  9. Spahn C; Laine RF; Pereira PM; Gómez-de-Mariscal E; von Chamier L; Conduit M; de Pinho MG; et al. "DeepBacs: Bacterial image analysis using open-source deep learning approaches". 2021. http://europepmc.org/abstract/PPR/PPR415602.
    10.1101/2021.11.03.467152
  10. Thevathasan JV; Kahnwald M; Cieslinski K; Hoess P; Peneti SK; Reitberger M; Heid D; et al. "Nuclear pores as versatile reference standards for quantitative superresolution microscopy". 2019. http://europepmc.org/abstract/PPR/PPR73672.
    10.1101/582668

Other

Other output
  1. The Field Guide to 3D Printing in Microscopy. 2021. Mario Del Rosario; Hannah S. Heil; Afonso Mendes; Vittorio Saggiomo; Ricardo Henriques. https://doi.org/10.20944/preprints202105.0352.v1.
    10.20944/preprints202105.0352.v1
  2. Physical mechanisms of ESCRT-III-driven cell division in archaea. 2021. L. Harker-Kirschneck; A. E. Hafner; T. Yao; A. Pulschen; F. Hurtig; C. Vanhille-Campos; D. Hryniuk; et al. https://doi.org/10.1101/2021.03.23.436559.
    10.1101/2021.03.23.436559
  3. Single-molecule super-resolution imaging of T-cell plasma membrane CD4 redistribution upon HIV-1 binding. 2021. Yue Yuan; Caron Jacobs; Isabel Llorente Garcia; Pedro M. Pereira; Scott P. Lawrence; Romain F. Laine; Mark Marsh; Ricardo Henriques. https://doi.org/10.1101/2021.01.05.425371.
    10.1101/2021.01.05.425371
  4. FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division. 2020. Kevin D. Whitley; Calum Jukes; Nicholas Tregidgo; Eleni Karinou; Pedro Almada; Ricardo Henriques; Cees Dekker; Séamus Holden. https://doi.org/10.1101/2020.07.01.182006.
    10.1101/2020.07.01.182006
  5. ZeroCostDL4Mic: an open platform to use Deep-Learning in Microscopy. 2020. Henriques, Ricardo. http://dx.doi.org/10.1101/2020.03.20.000133.
    10.1101/2020.03.20.000133
  6. Live cell imaging of the hyperthermophilic archaeon Sulfolobus acidocaldarius identifies complementary roles for two ESCRTIII homologues in ensuring a robust and symmetric cell division. 2020. Pulschen AA; Mutavchiev DR; Sebastian KN; Roubinet J; Roubinet M; Risa GT; van Wolferen M; et al. http://europepmc.org/abstract/PPR/PPR113606.
    10.1101/2020.02.18.953042
  7. Super-Beacons: open-source probes with spontaneous tuneable blinking compatible with live-cell super-resolution microscopy. 2020. Pedro M. Pereira; Nils Gustafsson; Mark Marsh; Musa M. Mhlanga; Ricardo Henriques. https://doi.org/10.1101/2020.01.20.912311.
    10.1101/2020.01.20.912311
  8. vLUME: 3D Virtual Reality for Single-molecule Localization Microscopy. 2020. Spark A; Kitching A; Esteban-Ferrer D; Handa A; Carr AR; Needham L; Ponjavic A; et al. http://europepmc.org/abstract/PPR/PPR109626.
    10.1101/2020.01.20.912733
  9. Closed mitosis requires local disassembly of the nuclear envelope. 2019. Gautam Dey; Siân Culley; Scott Curran; Ricardo Henriques; Wanda Kukulski; Buzz Baum. https://doi.org/10.1101/779769.
    10.1101/779769
  10. Fluctuation-Based Super-Resolution Traction Force Microscopy. 2019. Stubb A; Laine RF; Guzmán C; Henriques R; Jacquemet G; Ivaska J. http://europepmc.org/abstract/PPR/PPR92766.
    10.1101/772947
  11. Between Life and Death: Reducing Phototoxicity in Super-Resolution Microscopy. 2019. Henriques, Ricardo. http://dx.doi.org/10.20944/preprints201908.0319.v1.
    10.20944/preprints201908.0319.v1
  12. Artificial Intelligence for Microscopy: What You Should Know. 2019. Lucas von Chamier; Romain F. Laine; Ricardo Henriques. https://doi.org/10.20944%2Fpreprints201902.0004.v1.
    10.20944/preprints201902.0004.v1
  13. Fix your membrane receptor imaging: Actin cytoskeleton and CD4 membrane organization disruption by chemical fixation. 2018. Pedro M. Pereira; David Albrecht; Caron Jacobs; Mark Marsh; Jason Mercer; Ricardo Henriques. https://doi.org/10.1101/450635.
    10.1101/450635
  14. NanoJ: a high-performance open-source super-resolution microscopy toolbox. 2018. Romain Laine; Kalina Tosheva; Nils Gustafsson; Robert D. M. Gray; Pedro Almada; David Albrecht; Gabriel T. Risa; et al. https://doi.org/10.1101%2F432674.
    10.1088/1361-6463/ab0261
  15. Super-resolution fight club: A broad assessment of 2D & 3D single-molecule localization microscopy software. 2018. Sage D; Pham T; Babcock H; Lukes T; Pengo T; Chao J; Velmurugan R; et al. http://europepmc.org/abstract/PPR/PPR7580.
    10.1101/362517
  16. Automating multimodal microscopy with NanoJ-Fluidics. 2018. Pedro Almada; Pedro Pereira; Siân Culley; Ghislaine Caillol; Fanny Boroni-Rueda; Christina L. Dix; Romain F. Laine; et al. https://doi.org/10.1101%2F320416.
    10.1038/s41467-019-09231-9
  17. Nanoscale colocalization of NK cell activating and inhibitory receptors controls signal integration. 2018. David Tomaz; Pedro Matos Pereira; Nadia Guerra; Julian Dyson; Ricardo Henriques; Keith Gould. https://doi.org/10.1101%2F266429.
    10.1101/266429
  18. A hidden Markov model approach to characterizing the photo-switching behavior of fluorophores. 2017. Lekha Patel; Nils Gustafsson; Yu Lin; Raimund Ober; Ricardo Henriques; Edward Cohen. https://doi.org/10.1101%2F223875.
    10.1101/223875
  19. Content-Aware Image Restoration: Pushing the Limits of Fluorescence Microscopy. 2017. Martin Weigert; Uwe Schmidt; Tobias Boothe; Andreas Müller; Alexandr Dibrov; Akanksha Jain; Benjamin Wilhelm; et al. https://doi.org/10.1101%2F236463.
    10.1101/236463
Distinctions

Title

2019 Promotion to Professor Chair of Computational and Optiocal Biophysics
University College London, United Kingdom