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Emanuel V. Capela graduated in Biochemistry in 2014, by University of Aveiro, Portugal, where he received the "Best student admitted in the Bachelor of Biochemistry" Award. Then, he obtained his MSc in Biochemistry - Biomolecular Methods, from the same university, with the Master Thesis final classification of 20 (in a 0-20 scale), and more recently, he obtained his PhD in Chemical Engineering - Bioengineering with honour and distinction, from the University of Aveiro and Instituto Superior Técnico - University of Lisbon. Since 2014, he was author and co-author of 16 papers in international peer reviewed journals, with 2 articles being part of themed collections 2017 Green Chem and 2018 PCCP Hot Articles, 1 Green Chemistry Back Cover, and 1 Most Downloaded Fluid Phase Equilib Articles. He has published in diverse and multidisciplinary high impact journals, namely Green Chem, Sep Purif Technol, ACS Sustain Chem Eng, Chem Eur J, Phys Chem Chem Phys, J Chem Technol Biotechnol, Fluid Phase Equilib, ChemEngineering, Molecules, Biochem Mol Biol Educ and Chem Eng Educ. He was also author of 4 book chapter and 1 encyclopedia entry. The scientific network of Emanuel V. Capela is supported by the publications with 49 more distinct authors with diverse affiliations. He participated in more than 65 national and international conferences, where he presented several oral (35+, 9 of them by invitation) and poster communications (80+), with 1 "Best Poster Award", 1 "Honorable Mention to the Poster", received 1 Attendance Grant and won the 1st Place at a Conference Contest for Young Researchers and the 2nd Award in a Shark Tank Idea Contest. Besides, he was also a member of the organizing committee of 2 international conference, trainer at a winter school and chair in another international conference. He completed the supervision of 3 internship and 7 volunteering students, and was responsible for the supervision of the main research activities of 1 post-doctoral researcher, 8 MSc thesis, 5 BSc students, and 3 MSc scholarship grantees. Currently, he is the supervisor of 2 PhD students, 1 internship and 3 volunteering students (under the CICECO Young Scientist Program). In addition, he participated as a team member in 5 research projects, namely in one European Research Council (ERC) Grant, and received an FCT PhD Grant in the "Bioengineering and Biotechnology" panel. Emanuel V. Capela currently holds a position of Junior Researcher at CICECO - Aveiro Institute of Materials, University of Aveiro, Portugal. Previously, he worked as MSc Researcher and as Research Assistant at Institute for Bioengeneering and Biosciences (iBB), Instituto Superior Técnico, University of Lisbon, Portugal, as PhD student/researcher at CICECO and iBB, and also as a Guest Researcher at Faculty of Science and Technology (TNW), University of Twente, The Netherlands. He also acquired experience in the industry, having occupied a position of Research Associate in a biopharmaceutical company – FairJourney Biologics, S.A. –, and also a position of Innovation Project Manager at Frederico Mendes & Associados – Sociedade de Consultores, Lda. In the past years, he was dedicated to develop cost-effective and sustainable processes for the up- and/or downstream processing of several (bio)molecules, especially human antibodies and related biopharmaceuticals. Moreover, he worked with a new class of alternative solvents, ionic liquids, where his scientific interest devoted to these compounds includes their use as phase-forming components of separation liquid-liquid systems, or immobilized in solid supports as novel ligands in chromatographic stationary phases, for application in processes development.
Identification

Personal identification

Full name
Emanuel Augusto Vieira Capela

Citation names

  • Capela, Emanuel V.

Author identifiers

Ciência ID
1411-97A6-F6E2
ORCID iD
0000-0001-6924-3383
Google Scholar ID
4Vw41MkAAAAJ&hl
Researcher Id
C-6745-2016
Scopus Author Id
57190384051

Email addresses

  • emanuelcapela@ua.pt (Professional)

Telephones

Telephone
  • 916545501 (Personal)

Addresses

  • Campus Universitário de Santiago, 3810-193, Aveiro, Aveiro, Portugal (Professional)

Websites

Knowledge fields

  • Engineering and Technology - Industrial Biotechnology - Bioprocessing Technologies

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Elementary (A2) Intermediate (B1) Elementary (A2) Elementary (A2) Elementary (A2)
Education
Degree Classification
2022/01/10
Concluded
Philosophy Doctor (PhD) student in Chemical Engineering - specialization in Bioengineering (Doutoramento)
Universidade de Aveiro, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal
"Innovative and sustainable platforms for the downstream processing of antibody-based biopharmaceuticals" (THESIS/DISSERTATION)
Approved with honor and distinction
2016/06/30
Concluded
Master of Science (MSc) in Biochemistry - specialization in Biomolecular Methods (Mestrado)
Universidade de Aveiro, Portugal
"Production and purification of antibodies using aqueous biphasic systems composed of ionic liquids as adjuvants" (THESIS/DISSERTATION)
18 out of 20
2014/06/26
Concluded
Bachelor of Science (BSc) in Biochemistry (Licenciatura)
Universidade de Aveiro, Portugal
"Purification of antibodies using aqueous biphasic systems" (THESIS/DISSERTATION)
17 out of 20
2011/06/30
Concluded
High School in Sciences and Technologies (Ensino secundário)
Escola Secundária de Esmoriz, Portugal
18 out of 20
Affiliation

Science

Category
Host institution
Employer
2024/03/01 - Current Researcher (Research) Universidade de Aveiro, Portugal
Universidade de Aveiro CICECO, Portugal
2017/05/01 - 2022/01/10 Researcher (Research) Universidade de Aveiro CICECO, Portugal
2017/05/01 - 2022/01/10 Researcher (Research) Universidade de Lisboa Instituto Superior Técnico, Portugal
2016/10/15 - 2017/04/15 Research Assistant (Research) Universidade de Lisboa Instituto Superior Técnico, Portugal

Others

Category
Host institution
Employer
2022/11/07 - 2024/02/29 Innovation Project Manager (Associate) Frederico Mendes & Associados – Sociedade de Consultores, Lda, Portugal
2021/11/02 - 2022/10/30 Research Associate FairJourney Biologics SA, Portugal
Projects

Grant

Designation Funders
2017/05/01 - 2021/10/31 Purification of monoclonal antibodies (Immunoglobulin G, IgG) using aqueous biphasic systems composed of bio-based ionic liquids
SFRH/BD/126202/2016
PhD Student Fellow
Universidade de Aveiro CICECO, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2024/03/01 - Current InsectERA - The ERA of the insect industry
Researcher
Agência para a Competitividade e Inovação IP
2022/01/17 - 2023/07/16 mVACCIL - Improving the manufacturing of mRNA vaccines applying ionic liquids and integrated production-clarification processes
EXPL/BII-BTI/0731/2021
Universidade de Aveiro, Portugal

Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/10/15 - 2017/04/15 PureMAb - Multimodal chromatography as an alternative to pure chromatographic modes for the capture and polishing of antibody streams
PTDC/QEQ-PRS/0286/2014
Research Fellow
Universidade de Lisboa Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2015/09/15 - 2016/10/15 Multimodal chromatography as an alternative to pure chromatographic modes for the purification of monoclonal antibodies
IF/00048/2014/CP1214/CT0010
Researcher
Universidade de Lisboa Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2014/02/01 - 2014/06/28 IgY Technology: A purification platform using ionic-liquid-based aqueous biphasic systems
Grant Agreement Nº 337753
Universidade de Aveiro CICECO, Portugal
European Research Council
Concluded
Outputs

Publications

Book chapter
  1. Almeida, Jéssica S.; Capela, Emanuel V.; Ana P.M.Tavares; Mara G. Freire. Corresponding author: Ana P.M.Tavares. "Nucleic Acids Stabilization with Ionic Liquids and Deep Eutectic Solvents". In Properties and Applications of Ionic Liquids, edited by Noureddine Abidi; Julia L. Shamshina, 181-218. New York, United States: Nova Science Publishers, 2023.
    Published • https://doi.org/10.52305/HFEO4188
  2. Bairos, Jéssica; Capela, Emanuel V.; Tavares, Ana P.M.; Freire, Mara G.. "Monoclonal Antibodies as Therapeutic Agents for Inflammatory Diseases". In Frontiers in Clinical Drug Research: Anti-Infectives: Volume 8, 1-54. BENTHAM SCIENCE PUBLISHERS, 2021.
    10.2174/9789815039412121080003
  3. Capela, Emanuel V.; Coutinho, João A. P.; Freire, Mara G.. "Application of Ionic Liquids in Separation and Fractionation Processes". In Green Chemistry and Chemical Engineering, 637-665. Springer New York, 2019.
    Published • 10.1007/978-1-4939-9060-3_1005
  4. Capela, Emanuel V.; Aires-Barros, M. Raquel ; Freire, Mara G.; Azevedo, Ana M.. "Monoclonal Antibodies - Addressing the Challenges on the Manufacturing Processing of an Advanced Class of Therapeutic Agents". In Frontiers in Clinical Drug Research: Anti-Infectives Volume 4, edited by Atta-ur-Rahman, 142-203. Sharjah, United Arab Emirates: Bentham Science Publishers Ltd., 2017.
    Published • 10.2174/9781681084879117040007
Conference poster
  1. Mauro Rocha; Capela, Emanuel V.; Ana F. Pereira; Lucía Xavier; Berta Zecchi; Mara G. Freire. "Recovery of ferulic and p-coumaric acids from rice husk using cholinium-based ionic liquids". Paper presented in 7th Iberoamerican Meeting on Ionic Liquids (IMIL2024), 2024.
  2. João Vasco Valente; M. Raquel Aires-Barros; Ana M. Azevedo; Capela, Emanuel V.; Ana C.A. Sousa; Mara G. Freire. "Leveraging ionic liquids for single-step monoclonal antibody purification". Paper presented in 7th Iberoamerican Meeting on Ionic Liquids (IMIL2024), 2024.
  3. Capela, Emanuel V.; Pedro Moleiro; Güliz Akyüz; Vanessa Vieira; Luís C. Branco; Ana P.M. Tavares; Mara G. Freire. "Exploring the use of ionic liquids for the extraction and purification of proteins from insects". Paper presented in 7th Iberoamerican Meeting on Ionic Liquids (IMIL2024), 2024.
  4. Capela, Emanuel V.; Jéssica Bairos; Augusto Q. Pedro; Márcia C. Neves; M. Raquel Aires-Barros; Ana M. Azevedo; João A.P. Coutinho; Ana P.M. Tavares; Mara G. Freire. "Towards the purification of human antibodies using customizable supported ionic liquids as promising alternative matrices". Paper presented in 7th Iberoamerican Meeting on Ionic Liquids (IMIL2024), 2024.
  5. Capela, Emanuel V.; Pedro Moleiro; Güliz Akyüz; Vanessa Vieira; Ana P.M. Tavares; Mara G. Freire. "Development of an innovative extraction/precipitation process for proteins from Tenebrio molitor using sustainable approaches". Paper presented in Jornadas CICECO 2024, 2024.
  6. João Vasco Valente; M. Raquel Aires-Barros; Ana M. Azevedo; Capela, Emanuel V.; Ana C.A. Sousa; Mara G. Freire. "Ionic-liquid-mediated process envisioning the purification of monoclonal antibodies". Paper presented in Jornadas CICECO 2024, 2024.
  7. Ana P.M. Tavares; Pedro Moleiro; Güliz Akyüz; Vanessa Vieira; Capela, Emanuel V.; Luís C. Branco; Mara G. Freire. "Extraction of proteins from Tenebrio molitor flour using eficiente and more sustainable processes". Paper presented in I InsectERA Congress, 2024.
  8. João Vasco Valente; M. Raquel Aires-Barros; Ana M. Azevedo; Capela, Emanuel V.; Ana C.A. Sousa; Mara G. Freire. "A new approach to monoclonal antibody purification: ionic liquids for one-step processing". Paper presented in 5th CHRC Annual Summit (5CHRCAM), 2024.
  9. Capela, Emanuel V.; Ana Rita R. Teles; Ana Filipa M. Cláudio; João A.P. Coutinho; Mara G. Freire. "COSMO-RS as a powerful tool to characterize the polarity of ionic liquids and their mixtures". Paper presented in 16th National Physical Chemistry Meeting (16ENQF), 2024.
  10. Capela, Emanuel V.; Pedro Moleiro; Güliz Akyüz; Vanessa Vieira; Luís C. Branco; Ana P.M. Tavares; Mara G. Freire. "Development of a novel ionic liquid-based approach for the extraction and purification of proteins from insects". Paper presented in 16th National Physical Chemistry Meeting (16ENQF), 2024.
  11. Capela, Emanuel V.; Jéssica Bairos; Neves, Márcia C.; M. Raquel Aires-Barros; Ana M. Azevedo; Ana P.M.Tavares; João A.P. Coutinho; Mara G. Freire. "Downstream processing of antibodies using supported ionic liquid materials". Paper presented in 6th International Conference on Ionic Liquid-Based Materials, 2021.
  12. Ana B. Fonseca; Capela, Emanuel V.; Ana P.M.Tavares; Mara G. Freire. "Development of photo-reversible aqueous biphasic systems". Paper presented in Jornadas CICECO 2021, 2021.
  13. Ana F.C.S. Rufino; Bola, Joana M.; Capela, Emanuel V.; Maria V. Quental; João A.P. Coutinho; Mara G. Freire. "Double-reversible aqueous biphasic systems formed by cholinium-based ionic liquids". Paper presented in Jornadas CICECO 2021, 2021.
  14. Ana F.C.S. Rufino; Capela, Emanuel V.; Maria V. Quental; João A.P. Coutinho; Mara G. Freire. "Liquid-liquid equilibria of innovative double-responsive aqueous biphasic systems". Paper presented in 19th International Symposium on Solubility Phenomena and Related Equilibrium Processes, 2021.
  15. Ana F.C.S. Rufino; Capela, Emanuel V.; Maria V. Quental; João A.P. Coutinho; Mara G. Freire. "Stimuli responsive aqueous biphasic systems constituted by protic ionic liquids". Paper presented in 25th Annual Green Chemistry & Engineering Conference, 2021.
  16. Bola, Joana M.; Ana F.C.S. Rufino; Capela, Emanuel V.; João A.P. Coutinho; Mara G. Freire. "Development of double-reversible aqueous biphasic systems envisioning their application in separation processes". Paper presented in 25th Annual Green Chemistry & Engineering Conference, 2021.
  17. Bola, Joana M.; Ana F.C.S. Rufino; Capela, Emanuel V.; João A.P. Coutinho; Mara G. Freire. "Development of double-reversible aqueous biphasic systems envisioning their application in biochemical applications". Paper presented in XII Biochemistry Day at University of Aveiro, 2021.
  18. Ana F.C.S. Rufino; Capela, Emanuel V.; Maria V. Quental; João A.P. Coutinho; Mara G. Freire. "Switchable aqueous biphasic systems formed with protic ionic liquids". Paper presented in Jornadas CICECO 2020, 2020.
  19. Capela, Emanuel V.; Alexandre E. Santiago; Ana F.C.S. Rufino; Ana P.M.Tavares; Pereira, Matheus M.; Aminou Mohamadou; João A.P. Coutinho; et al. "Applying ionic-liquid-based strategies in cell culture supernatants bioprocessing for monoclonal antibodies recovery". Paper presented in Jornadas CICECO 2020, 2020.
  20. Rufino, Ana F.C.S.; Capela, Emanuel V.; Quental, Maria V.; Coutinho, João A.P.; Freire, Mara G.. "Reversible aqueous biphasic systems for biotechnology applications". Paper presented in Congress of Microbiology and Biotechnology 2019 (Microbiotec’19), 2019.
  21. Passos, Helena; Dinis, Teresa B.V.; Capela, Emanuel V.; Quental, Maria V.; Gomes, Joana M.; Resende, Judite; Madeira, Pedro P.; Freire, Mara G.; Coutinho, João A.P.. "Mechanisms ruling the partition of solutes in ionic-liquid-based aqueous biphasic systems – multiple effects of ionic liquids". Paper presented in Biopartitioning and Purification Conference 2019 (BPP2019), 2019.
  22. Capela, Emanuel V.; Coutinho, João A.P.; Aires-Barros, M. Raquel; Azevedo, Ana M.; Freire, Mara G.. "Purification of immunoglobulin G from human serum using ionic-liquid-based aqueous biphasic systems". Paper presented in 4th International Conference on Ionic Liquids in Separation and Purification Technology (ILSEPT 2019), 2019.
  23. Capela, Emanuel V.; Santiago, Alexandre E.; Rufino, Ana F.C.S.; Tavares, Ana P.M.; Pereira, Matheus M.; Mohamadou, Aminou; Coutinho, João A.P.; et al. "Recovery of monoclonal antibodies using novel glycine-betaine analogues ionic liquids". Paper presented in 4th International Conference on Ionic Liquids in Separation and Purification Technology (ILSEPT 2019), 2019.
  24. Rufino, Ana F.C.S.; Capela, Emanuel V.; Quental, Maria V.; Coutinho, João A.P.; Freire, Mara G.. "Aqueous biphasic systems formed by protic ionic liquids and polymers". Paper presented in 3rd Doctoral Congress in Engineering (DCE 19), 2019.
  25. Capela, Emanuel V.; Coutinho, João A.P.; Aires-Barros, M. Raquel; Azevedo, Ana M.; Freire, Mara G.. "Human serum bioprocessing – towards the recovery of antibodies applying ionic liquids". Paper presented in Jornadas CICECO 2019, 2019.
  26. Capela, Emanuel V.; Teles, Ana Rita R.; Cláudio, Ana Filipa M.; Coutinho, João A.P.; Freire, Mara G.. "Mixtures of ionic liquids: addressing their polarity by solvatochromic parameters and COSMO-RS predictions". Paper presented in Jornadas CICECO 2019, 2019.
  27. Capela, Emanuel V.; Valente, Ana I.; Rodriguez, Oscar; Coutinho, João A.P.; Soto, Ana; Freire, Mara G.; Tavares, Ana P.M.. "Ionic-liquid-based strategies for the extraction and laccase activity enhancement". Paper presented in Jornadas CICECO 2019, 2019.
  28. Capela, Emanuel V.; Santiago, Alexandre E.; Rufino, Ana F.C.S.; Tavares, Ana P.M.; Pereira, Matheus M.; Mohamadou, Aminou; Coutinho, João A.P.; et al. "Three-phase partitioning systems as a viable strategy for the recovery of monoclonal antibodies". Paper presented in Jornadas CICECO 2019, 2019.
  29. Fonseca, Ana; Capela, Emanuel V.; Coutinho, João A.P.; Tripathi, Kumud Malika; Tavares, Ana P.M.; Freire, Mara G.. "Sustainable pear graphene aerogels as novel materials for the purification of human antibodies". Paper presented in Jornadas CICECO 2019, 2019.
  30. Capela, Emanuel V.; Bairos, Jéssica; Neves, Márcia C.; Coutinho, João A.P.; Tavares, Ana P.M.; Freire, Mara G.. "Purification of antibodies using supported ionic liquid materials". Paper presented in Jornadas CICECO 2019, 2019.
  31. Capela, Emanuel V.; Rufino, Ana F.C.S.; Quental, Maria V.; Coutinho, João A.P.; Freire, Mara G.. "Reversible pH-dependent aqueous biphasic systems formed by protic ionic liquids and polymers". Paper presented in Jornadas CICECO 2019, 2019.
  32. Kopilovic, Bojan; Capela, Emanuel V.; Maric, Aleksandar; Coutinho, João A.P.; Gadžuric, Slobodan; Freire, Mara G.. "Novel thermoreversible platforms based on protic ionic liquids for biotechnological applications". Paper presented in Jornadas CICECO 2019, 2019.
  33. Capela, Emanuel V.; Carvalho, Bruno J.; Silva, Cláudia G.; Carabineiro, Sónia; Coutinho, João A.P.; Freire, Mara G.; Tavares, Ana P.M.. "Carbon xerogels as efficient nanomaterials for human antibodies purification from serum samples". Paper presented in Jornadas CICECO 2019, 2019.
  34. Rufino, Ana F.C.S.; Santiago, Alexandre E.; Capela, Emanuel V.; Tavares, Ana P.M.; Pereira, Matheus M.; Mohamadou, Aminou; Coutinho, João A.P.; et al. "Ionic-liquid-based aqueous biphasic systems for the recovery of monoclonal antibodies". Paper presented in 4th Meeting of Medicinal Biotechnology (MMB 2019), 2019.
  35. Bairos, Jéssica; Santos, Maria; Capela, Emanuel V.; Neves, Márcia C.; Tavares, Ana P.M.; Freire, Mara G.. "The two sides of the use of supported ionic liquid (SIL) materials". Paper presented in 4th Meeting of Medicinal Biotechnology (MMB 2019), 2019.
  36. Capela, Emanuel V.; Valente, Ana I.; Rodriguez, Oscar; Coutinho, João A.P.; Soto, Ana; Freire, Mara G.; Tavares, Ana P.M.. "Laccase extraction and activity enhancement using ionic-liquid-based strategies – toward its application in the medicinal field". Paper presented in 4th Meeting of Medicinal Biotechnology (MMB 2019), 2019.
  37. Fonseca, Ana; Capela, Emanuel V.; Coutinho, João A.P.; Tripathi, Kumud Malika; Tavares, Ana P.M.; Freire, Mara G.. "Sustainable pear graphene aerogels as novel materials for the purification of antibodies". Paper presented in XI Biochemistry Day at University of Aveiro, 2019.
  38. Carvalho, Bruno J.; Capela, Emanuel V.; Silva, Cláudia G.; Freire, Mara G.; Tavares, Ana P.M.. "Novel purification strategies for human antibodies based on carbon xerogels". Paper presented in XI Biochemistry Day at University of Aveiro, 2019.
  39. Bairos, Jéssica; Santos, Maria; Capela, Emanuel V.; Neves, Márcia C.; Tavares, Ana P.M.; Freire, Mara G.. "The two sides of the use of supported ionic liquid (SIL) materials". Paper presented in XI Biochemistry Day at University of Aveiro, 2019.
  40. Capela, Emanuel V.; Fonseca, Ana; Coutinho, João A.P.; Tripathi, Kumud Malika; Tavares, Ana P.M.; Freire, Mara G.. "Capture and purification of human antibodies using sustainable pear graphene aerogels". Paper presented in XII National Meeting of Biochemistry Students (XII ENEBIOQ), 2019.
  41. Rufino, Ana F.C.S.; Capela, Emanuel V.; Quental, Maria V.; Coutinho, João A.P.; Freire, Mara G.. "Reversible aqueous biphasic systems formed by ionic liquids and polymers". Paper presented in XXIV Encontro Luso-Galego de Química (XXIV ELGQ), 2018.
  42. Capela, Emanuel V.; Teles, Ana Rita R.; Cláudio, Ana Filipa M.; Coutinho, João A.P.; Freire, Mara G.. "Solvatochromic parameters of mixtures of ionic liquids: experimental studies and COSMO-RS prediction". Paper presented in 27th EuCheMS Conference on Molten Salts and Ionic Liquids (EuCheMSIL 2018), 2018.
  43. Capela, Emanuel V.; Quental, Maria V.; Domingues, Pedro; Coutinho, João A.P.; Freire, Mara G.. "One-step separation of aromatic and aliphatic amino acids using aqueous biphasic systems". Paper presented in 27th EuCheMS Conference on Molten Salts and Ionic Liquids (EuCheMSIL 2018), 2018.
  44. Capela, Emanuel V.; Santos, João H.P.M.; Boal-Palheiros, Isabel; Coutinho, João A.P.; Ventura, Sónia P.M.; Freire, Mara G.. "A simple laboratory approach for the determination and characterization of ternary phase diagrams for Chemical Engineering undergraduate students". Paper presented in 13th International Chemical and Biological Engineering Conference (CHEMPOR 2018), 2018.
  45. Santiago, Alexandre E.; Capela, Emanuel V.; Tavares, Ana P.M.; Pereira, Matheus M.; Mohamadou, Aminou; Coutinho, João A.P.; Aires-Barros, M. Raquel; Azevedo, Ana M.; Freire, Mara G.. "Development of an alternative bio-based process for the extraction and purification of monoclonal antibodies". Paper presented in 13th International Chemical and Biological Engineering Conference (CHEMPOR 2018), 2018.
  46. Capela, Emanuel V.; Santiago, Alexandre E.; Tavares, Ana P.M.; Mohamadou, Aminou; Coutinho, João A.P.; Aires-Barros, M. Raquel; Azevedo, Ana M.; Freire, Mara G.. "Innovative purification platform of monoclonal antibodies using biocompatible ionic liquids". Paper presented in 12th European Symposium on Biochemical Engineering Sciences (ESBES2018), 2018.
  47. Capela, Emanuel V.; Coutinho, João A.P.; Aires-Barros, M. Raquel; Azevedo, Ana M.; Freire, Mara G.. "Monoclonal antibodies downstream processing: an alternative ionic-liquid-based approach". Paper presented in Jornadas CICECO 2018, 2018.
  48. Santiago, Alexandre E.; Capela, Emanuel V.; Tavares, Ana P.M.; Coutinho, João A.P.; Aires-Barros, M. Raquel; Azevedo, Ana M.; Freire, Mara G.. "Innovative bio-based purification process for monoclonal antibodies". Paper presented in Jornadas CICECO 2018, 2018.
  49. Teles, Ana Rita R.; Capela, Emanuel V.; Cláudio, Ana Filipa M.; Coutinho, João A.P.; Freire, Mara G.. "Solvatochromic parameters of mixtures of ionic liquids: experimental studies and COSMO-RS predictions". Paper presented in Jornadas CICECO 2018, 2018.
  50. Santiago, Alexandre E.; Capela, Emanuel V.; Tavares, Ana P.M.; Azevedo, Ana M.; Freire, Mara G.. "Bio-based downstream process development for therapeutic monoclonal antibodies from Chinese Hamster Ovary cell culture supernatant". Paper presented in X Biochemistry Day at University of Aveiro, 2018.
  51. Capela, Emanuel V.; Silva-Santos, A. Rita; Campos-Pinto, Isabel; Rodríguez, Miguel Arévalo; Gavara, Poondi Rajesh; Fernandez-Lahore, Marcelo; Aires-Barros, M. Raquel; Azevedo, Ana M.. "LYTAG-driven purification strategies as a key to integrate and intensify the downstream processing of monoclonal antibodies". Paper presented in Congress of Microbiology and Biotechnology 2017 (Microbiotec’17), 2017.
  52. Capela, Emanuel V.; Quental, Maria V.; Domingues, Pedro; Coutinho, João A.P.; Freire, Mara G.. "Development of a novel ionic-liquid-based platform for the separation of aromatic and aliphatic amino acid mixtures". Paper presented in Congress of Microbiology and Biotechnology 2017 (Microbiotec’17), 2017.
  53. Capela, Emanuel V.; Quental, Maria V.; Coutinho, João A.P.; Freire, Mara G.. "One-step separation of aromatic and aliphatic amino acids using ionic-liquid-based strategies". Paper presented in Biopartitioning and Purification Conference 2017 (BPP2017), 2017.
  54. Passos, Helena; Dinis, Teresa B.V.; Capela, Emanuel V.; Quental, Maria V.; Gomes, Joana M.; Resende, Judite; Madeira, Pedro P.; Freire, Mara G.; Coutinho, João A.P.. "Factors driving solute partition in ionic-liquid-based aqueous biphasic systems". Paper presented in Biopartitioning and Purification Conference 2017 (BPP2017), 2017.
  55. Capela, Emanuel V.; Rosa, Sara A.S.L.; Coutinho, João A.P.; Aires-Barros, M. Raquel; Azevedo, Ana M.; Freire, Mara G.. "Novel ionic-liquid-based strategies for the downstream processing of monoclonal antibodies". Paper presented in Encontro Ciência 2017 - Encontro com a Ciência e Tecnologia em Portugal, 2017.
  56. Capela, Emanuel V.; Rosa, Sara A.S.L.; Coutinho, João A.P.; Aires-Barros, M. Raquel; Azevedo, Ana M.; Freire, Mara G.. "Novel ionic-liquid-based strategies for the downstream processing of monoclonal antibodies". Paper presented in University of Aveiro (UA) Research Day 2017 (RD 2017), 2017.
  57. Capela, Emanuel V.; Quental, Maria V.; Coutinho, João A.P.; Freire, Mara G.. "Remarkable platforms for the selective separation of amino acids based on the use of aqueous biphasic systems composed of ionic liquids". Paper presented in Iberoamerican Meeting on Ionic Liquids 2017 (IMIL2017), 2017.
  58. Capela, Emanuel V.; Rosa, Sara A.S.L.; Coutinho, João A.P.; Aires-Barros, M. Raquel; Azevedo, Ana M.; Freire, Mara G.. "Exploring the use of ionic liquids in the extraction and purification of monoclonal antibodies directly from CHO cell culture supernatants". Paper presented in Iberoamerican Meeting on Ionic Liquids 2017 (IMIL2017), 2017.
  59. Capela, Emanuel V.; Rosa, Sara A.S.L.; Coutinho, João A.P.; Aires-Barros, M. Raquel; Freire, Mara G.; Azevedo, Ana M.. "Purification of monoclonal antibodies from cell culture supernatants using aqueous biphasic systems constituted by ionic liquids". Paper presented in III National Meeting of Biotechnology Students (III ENEBT), 2017.
  60. Capela, Emanuel V.; Quental, Maria V.; Domingues, Pedro; Coutinho, João A.P.; Freire, Mara G.. "Efficient separation of aromatic and aliphatic amino acid mixtures using ionic-liquid-based processes". Paper presented in III National Meeting of Biotechnology Students (III ENEBT), 2017.
  61. Capela, Emanuel V.; Teles, Ana Rita R.; Cláudio, Ana Filipa M.; Coutinho, João A.P.; Freire, Mara G.. "Characterization of the solvatochromic parameters of binary mixtures of ionic liquids: experimental and COSMO-RS approaches". Paper presented in Ionic Liquids Winter School (ILWS2017), 2017.
  62. Capela, Emanuel V.; Quental, Maria V.; Coutinho, João A.P.; Freire, Mara G.. "High-efficient approach for the selective separation of amino acids based on the use of aqueous biphasic systems composed of ionic liquids". Paper presented in International Symposium on the Separation of Proteins, Peptides and Polynucleotides 2016 (ISPPP2016), 2016.
  63. Capela, Emanuel V.; Almeida, Mafalda R.; Coutinho, João A.P.; Freire, Mara G.. "Exploring ionic liquids for the development of a purification platform for therapeutic immunoglobulin Y (IgY) from egg yolk". Paper presented in International Symposium on the Separation of Proteins, Peptides and Polynucleotides 2016 (ISPPP2016), 2016.
  64. Capela, Emanuel V.; Campos-Pinto, Isabel; Rosa, Sara A.S.L.; Aires-Barros, M. Raquel; Azevedo, Ana M.; Freire, Mara G.. "Purification Of Monoclonal Antibodies From Cell Cultures Supernatants Using Aqueous Biphasic Systems With Ionic Liquids". Paper presented in European Symposium on Biochemical Engineering Sciences 2016 (ESBES2016), 2016.
  65. Capela, Emanuel V.; Santos, João H.P.M.; Boal-Palheiros, Isabel; Coutinho, João A.P.; Ventura, Sónia P.M.; Freire, Mara G.. "Aqueous Biphasic Systems For The Extraction Of Food Colorants: A Laboratory Experiment". Paper presented in European Symposium on Biochemical Engineering Sciences 2016 (ESBES2016), 2016.
  66. Capela, Emanuel V.; Almeida, Mafalda R.; Coutinho, João A.P.; Freire, Mara G.. "Platform For The Purification Of Immunoglobulin Y (IgY) From Egg Yolk Using Aqueous Biphasic Systems". Paper presented in European Symposium on Biochemical Engineering Sciences 2016 (ESBES2016), 2016.
  67. Quental, Maria V.; Capela, Emanuel V.; Coutinho, João A.P.; Freire, Mara G.. "Selective Separation Of Amino Acids Using Aqueous Biphasic Systems Composed Of Ionic Liquids". Paper presented in European Symposium on Biochemical Engineering Sciences 2016 (ESBES2016), 2016.
  68. Capela, Emanuel V.; Teles, Ana Rita R.; Cláudio, Ana Filipa M.; Coutinho, João A.P.; Freire, Mara G.. "Binary Mixtures of Ionic Liquids: Characterization of their Solvatochromic Parameters". Paper presented in 12th Portuguese Meeting on Physical Chemistry/1st Symposium on Computational Chemistry (XII ENQF), 2016.
  69. Capela, Emanuel V.; Teles, Ana Rita R.; Cláudio, Ana Filipa M.; Kurnia, Kiki A.; Coutinho, João A.P.; Freire, Mara G.. "Hydrogen-bond Acidity and Basicity of Mixtures of Ionic Liquids: Experimental and COSMO-RS Approaches". Paper presented in Jornadas CICECO 2016, 2016.
  70. Capela, Emanuel V.; Quental, Maria V.; Coutinho, João A.P.; Freire, Mara G.. "Aqueous Biphasic Systems Composed of Ionic Liquids for the Selective Separation of Amino Acids". Paper presented in 5th Portuguese Young Chemists Meeting and 1st European Young Chemists Meeting (5th PYCheM & 1st EYCheM), 2016.
  71. Capela, Emanuel V.; Almeida, Mafalda R.; Coutinho, João A.P.; Freire, Mara G.. "Purification of therapeutic Immunoglobulin Y (IgY) from egg yolk using Aqueous Biphasic Systems". Paper presented in IV National Meeting of Chemistry Students (IV ENEQUI), 2016.
  72. Capela, Emanuel V.; Quental, Maria V.; Coutinho, João A.P.; Freire, Mara G.. "Selective extraction of amino acids by aqueous biphasic systems composed of ionic liquids". Paper presented in IV National Meeting of Chemistry Students (IV ENEQUI), 2016.
  73. Capela, Emanuel V.; Cláudio, Ana Filipa M.; Coutinho, João A.P.; Freire, Mara G.. "Hydrogen-bond Acidity and Basicity of Mixtures of Ionic Liquids: Experimental and COSMO-RS Approaches". Paper presented in IV National Meeting of Chemistry Students (IV ENEQUI), 2016.
  74. Capela, Emanuel V.; Cláudio, Ana Filipa M.; Coutinho, João A.P.; Freire, Mara G.. "Characterization of Mixtures of Ionic Liquids by their Solvatochromic Parameters". Paper presented in 2nd EuCheMS Congress on Green and Sustainable Chemistry (2nd EuGSC), 2015.
  75. Capela, Emanuel V.; Quental, Maria V.; Coutinho, João A.P.; Freire, Mara G.. "Aqueous biphasic systems composed of ionic liquids: enhanced platforms for the selective separation of amino acids". Paper presented in 2nd EuCheMS Congress on Green and Sustainable Chemistry (2nd EuGSC), 2015.
  76. Capela, Emanuel V.; Almeida, Mafalda R.; Coutinho, João A.P.; Freire, Mara G.. "Purification of Immunoglobulin Y (IgY) using Aqueous Biphasic Systems". Paper presented in 2nd EuCheMS Congress on Green and Sustainable Chemistry (2nd EuGSC), 2015.
  77. Capela, Emanuel V.; Cláudio, Ana Filipa M.; Coutinho, João A.P.; Freire, Mara G.. "Hydrogen-bond Acidity and Basicity of Mixtures of Ionic Liquids: Experimental and COSMO-RS Approaches". Paper presented in Iberoamerican Meeting on Ionic Liquids (IMIL2015), 2015.
  78. Capela, Emanuel V.; Quental, Maria V.; Coutinho, João A.P.; Freire, Mara G.. "Aqueous biphasic systems composed of ionic liquids and amino acids as remarkable selective extraction approaches". Paper presented in Iberoamerican Meeting on Ionic Liquids (IMIL2015), 2015.
  79. Capela, Emanuel V.; Santos, João H.P.M.; Ventura, Sónia P.M.; Boal-Palheiros, Isabel; Freire, Mara G.. "Characterization of Aqueous Biphasic Systems Composed of Poly(ethyleneglycol) and Sodium Carbonate". Paper presented in Biopartitioning & Purification Conference 2015 (BPP2015), 2015.
  80. Capela, Emanuel V.; Quental, Maria V.; Coutinho, João A.P.; Freire, Mara G.. "Selective extraction of amino acids by aqueous biphasic systems composed of ionic liquids". Paper presented in Biopartitioning & Purification Conference 2015 (BPP2015), 2015.
  81. Almeida, Mafalda R.; Capela, Emanuel V.; Passos, Helena; Coutinho, João A.P.; Freire, Mara G.. "Addition of ionic liquids to tune the phases’ polarities of polymer-salt aqueous biphasic systems". Paper presented in 20th European Conference on Thermophysical Properties (ECTP2014), 2014.
  82. Almeida, Mafalda R.; Capela, Emanuel V.; Passos, Helena; Coutinho, João A.P.; Freire, Mara G.. "Tailoring the phases’ polarities of polymer-salt aqueous biphasic systems by the addition of ionic liquids". Paper presented in 2nd International Conference on Ionic Liquids in Separation and Purification Technology (ILSEPT 2014), 2014.
Encyclopedia entry
  1. Capela, Emanuel V.; Coutinho, João A.P.; Freire, Mara G.. "Application of Ionic Liquids in Separation and Fractionation Processes". In Encyclopedia of Sustainability Science and Technology, edited by Meyers, Robert A.. Springer New York, 2018. https://link.springer.com/referenceworkentry/10.1007/978-1-4939-2493-6_1005-1.
    Published • 10.1007/978-1-4939-2493-6_1005-1
Journal article
  1. Rufino, Ana F. C. S.; Capela, Emanuel V.; Quental, Maria V.; Coutinho, João A. P.; Vraneš, Milan B.; Gadžuric, Slobodan B.; Francisca A. e Silva; Freire, Mara G.. "Widening the Stimuli-Responsiveness of Aqueous Biphasic Systems by Changing the Ionic Liquid Cation Basicity". Chemistry – A European Journal (2024): http://dx.doi.org/10.1002/chem.202403605.
    10.1002/chem.202403605
  2. Capela, Emanuel V.; Magnis, Ilaria; Rufino, Ana F.C.S.; Torres-Acosta, Mario A.; Aires-Barros, M. Raquel; Coutinho, João A.P.; Azevedo, Ana M.; e Silva, Francisca A.; Freire, Mara G.. "Using three-phase partitioning for the purification and recovery of antibodies from biological media". Separation and Purification Technology 316 (2023): 123823. http://dx.doi.org/10.1016/j.seppur.2023.123823.
    10.1016/j.seppur.2023.123823
  3. Rufino, Ana F.C.S.; Bola, Joana M.; Capela, Emanuel V.; Coutinho, João A. P.; e Silva, Francisca A.; Freire, Mara G.. "Double-Stimuli-Responsive (Temperature and pH) Aqueous Biphasic Systems Comprising Ionic Liquids". ACS Sustainable Chemistry & Engineering 11 16 (2023): 6343-6351. http://dx.doi.org/10.1021/acssuschemeng.3c00059.
    10.1021/acssuschemeng.3c00059
  4. Capela, Emanuel V.; Bairos, Jéssica; Pedro, Augusto Q.; Neves, Márcia C.; Raquel Aires-Barros, M.; Azevedo, Ana M.; Coutinho, João A.P.; Tavares, Ana P.M.; Freire, Mara G.. "Supported ionic liquids as customizable materials to purify immunoglobulin G". Separation and Purification Technology 305 (2023): 122464. http://dx.doi.org/10.1016/j.seppur.2022.122464.
    10.1016/j.seppur.2022.122464
  5. Almeida, Jéssica S.; Capela, Emanuel V.; Loureiro, Ana M.; Tavares, Ana P. M.; Freire, Mara G.. "An Overview on the Recent Advances in Alternative Solvents as Stabilizers of Proteins and Enzymes". ChemEngineering 6 4 (2022): 51. http://dx.doi.org/10.3390/chemengineering6040051.
    10.3390/chemengineering6040051
  6. Bernardo, Sandra C.; Capela, Emanuel V.; Pereira, Jorge F. B.; Ventura, Sónia P. M.; Freire, Mara G.; Coutinho, João A. P.. "Opposite Effects Induced by Cholinium-Based Ionic Liquid Electrolytes in the Formation of Aqueous Biphasic Systems Comprising Polyethylene Glycol and Sodium Polyacrylate". Molecules 26 21 (2021): 6612. http://dx.doi.org/10.3390/molecules26216612.
    10.3390/molecules26216612
  7. Capela, Emanuel V.; Valente, Ana I.; Nunes, João C.F.; Magalhães, Flávia F.; Rodríguez, Oscar; Soto, Ana; Freire, Mara G.; Tavares, Ana P.M.. "Insights on the laccase extraction and activity in ionic-liquid-based aqueous biphasic systems". Separation and Purification Technology (2020): 117052. http://dx.doi.org/10.1016/j.seppur.2020.117052.
    Published • 10.1016/j.seppur.2020.117052
  8. Capela, Emanuel V.; Santiago, Alexandre E.; Rufino, Ana F. C. S.; Tavares, Ana P. M.; Pereira, Matheus M.; Mohamadou, Aminou; Aires-Barros, M. Raquel; et al. "Sustainable strategies based on glycine–betaine analogue ionic liquids for the recovery of monoclonal antibodies from cell culture supernatants". Green Chemistry 21 20 (2019): 5671-5682. http://dx.doi.org/10.1039/c9gc02733e.
    Published • 10.1039/c9gc02733e
  9. Capela, Emanuel V.; Santos, João H.P.M.; Isabel Boal-Palheiros; Pedro J. Carvalho; Coutinho, Joao A. P.; Ventura, Sónia P.M.; Freire, Mara G.. "A simple approach for the determination and characterization of ternary phase diagrams of aqueous two-phase systems composed of water, polyethylene glycol and sodium carbonate". Chemical Engineering Education 53 2 (2019): 112-120. https://journals.flvc.org/cee/article/view/108013/0.
    Published
  10. Santos, João H.P.M.; Capela, Emanuel V.; Boal-Palheiros, Isabel; Coutinho, João A.P.; Freire, Mara G.; Ventura, Sónia P.M.. "Aqueous biphasic systems in the separation of food colorants". Biochemistry and Molecular Biology Education 46 4 (2018): 390-397. http://dx.doi.org/10.1002/bmb.21125.
    Published • 10.1002/bmb.21125
  11. Passos, Helena; Dinis, Teresa B.V.; Capela, Emanuel V.; Quental, Maria V.; Gomes, Joana; Resende, Judite; Madeira, Pedro P.; Freire, Mara G.; Coutinho, João A.P.. "Mechanisms ruling the partition of solutes in ionic-liquid-based aqueous biphasic systems – the multiple effects of ionic liquids". Physical Chemistry Chemical Physics 20 13 (2018): 8411-8422. http://dx.doi.org/10.1039/c8cp00383a.
    Published • 10.1039/c8cp00383a
  12. Campos-Pinto, Isabel; Capela, Emanuel V.; Silva-Santos, A. Rita; Rodríguez, Miguel Arévalo; Gavara, Poondi Rajesh; Fernandez-Lahore, Marcelo; Aires-Barros, M. Raquel ; Azevedo, Ana M.. "LYTAG-driven purification strategies for monoclonal antibodies using quaternary amine ligands as affinity matrices". Journal of Chemical Technology & Biotechnology 93 7 (2017): 1966-1974. http://dx.doi.org/10.1002/jctb.5460.
    Published • 10.1002/jctb.5460
  13. Teles, Ana Rita R.; Capela, Emanuel V.; Carmo, Rafael S.; Coutinho, João A.P.; Silvestre, Armando J.D.; Freire, Mara G.. "Solvatochromic parameters of deep eutectic solvents formed by ammonium-based salts and carboxylic acids". Fluid Phase Equilibria 448 (2017): 15-21. http://dx.doi.org/10.1016/j.fluid.2017.04.020.
    Published • 10.1016/j.fluid.2017.04.020
  14. Taha, Mohamed; Quental, Maria V.; e Silva, Francisca A.; Capela, Emanuel V.; Freire, Mara G.; Ventura, Sónia P.M.; Coutinho, João A.P.. "Good's buffer ionic liquids as relevant phase-forming components of self-buffered aqueous biphasic systems". Journal of Chemical Technology & Biotechnology 92 9 (2017): 2287-2299. http://dx.doi.org/10.1002/jctb.5222.
    Published • 10.1002/jctb.5222
  15. Capela, Emanuel V.; Quental, Maria V.; Domingues, Pedro; Coutinho, João A.P.; Freire, Mara G.. "Effective separation of aromatic and aliphatic amino acid mixtures using ionic-liquid-based aqueous biphasic systems". Green Chemistry 19 8 (2017): 1850-1854. http://dx.doi.org/10.1039/c6gc03060b.
    Published • 10.1039/c6gc03060b
  16. Teles, Ana Rita R.; Dinis, Teresa B.V.; Capela, Emanuel V.; Santos, Luís M.N.B.F.; Pinho, Simão P.; Freire, Mara G.; Coutinho, João A.P.. "Solubility and solvation of monosaccharides in ionic liquids". Physical Chemistry Chemical Physics 18 29 (2016): 19722-19730. http://dx.doi.org/10.1039/c6cp03495k.
    Published • 10.1039/c6cp03495k
Newsletter article
  1. Capela, Emanuel V.; Mara G. Freire; Esteves, Catarina V.; Luís C. Branco. "Líquidos iónicos: solventes alternativos e sustentáveis do presente com impacto nos alimentos inovadores do futuro", NEWSLETTER #5 Agenda Mobilizadora InsectERA, 2024
Thesis / Dissertation
  1. "Innovative and sustainable platforms for the downstream processing of antibody-based biopharmaceuticals". PhD, Universidade de Aveiro, 2022. http://hdl.handle.net/10773/33484.
  2. Capela, Emanuel V.. "Production and purification of antibodies using aqueous biphasic systems composed of ionic liquids as adjuvants". Master, Universidade de Aveiro, 2016. http://hdl.handle.net/10773/16747.
  3. Capela, Emanuel V.. "Purification of antibodies using aqueous biphasic systems". Degree, Universidade de Aveiro, 2014.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/12 Extraction and valorization of insect proteins for the development of novel food products I Biotechnology Symposium at University of Évora
2024/09 Extraction of proteins from Tenebrio molitor flour using sustainable approaches 4th International Conference on Natural Products and Human Health (ICNPHH-2024)
2024/07 RemAb: Reshaping mAbs biomanufacturing with ProA alternatives Research Summit 2024 (RS 2024)
2024/07 Extraction of proteins from Tenebrio molitor flour using deep eutectic solvents 16th National Physical Chemistry Meeting (16ENQF)
2024/06 Carreer options in Industry AIM Further 2024 - “Where will the future take me? Academia vs Industry”
2021/11 Separation of monoclonal antibodies using ionic-liquid-based aqueous biphasic systems 40th International Symposium on the Separation of Proteins, Peptides & Polynucleotides (ISPPP 2021)
2021/03 Ion Exchange in Aqueous Biphasic Systems 14th Meeting of Physical Chemistry
2021/03 Development of double-reversible aqueous biphasic systems based in protic and aprotic ionic liquids 14th Meeting of Physical Chemistry
2020/06 Towards the development of cost-effective downstream processes for monoclonal antibodies Research Summit 2020
University of Aveiro
2020/04 Stabilization and activation of laccase from Trametes versicolor in aqueous solutions of glycine-betaine analogue ionic liquids XI Symposium on Bioengineering
Faculty of Engineering of University of Porto (FEUP) (Oporto, Portugal)
2019/09 Capture and purification of monoclonal antibodies using supported ionic liquid phase materials 4th International Conference on Ionic Liquids in Separation and Purification Technology (ILSEPT 2019)
(Sitges, Spain)
2019/06 Avian antibodies – he(gg)roes that can save lives Jornadas CICECO 2019
University of Aveiro (Aveiro, Portugal)
2019/06 Towards the development of effective downstream processes for monoclonal antibodies Research Summit 2019
University of Aveiro (Aveiro, Portugal)
2019/06 Effective separation of amino acids mixtures using ionic-liquid-based approaches 3rd Doctoral Congress in Engineering (DCE 19)
Faculty of Engineering of University of Porto (FEUP) (Oporto, Portugal)
2019/06 Extraction of antibodies from human serum using ionic-liquid-based approaches 3rd Doctoral Congress in Engineering (DCE 19)
Faculty of Engineering of University of Porto (FEUP) (Oporto, Portugal)
2019/06 Recovery of monoclonal antibodies using aqueous biphasic systems formed by ionic liquids 3rd Doctoral Congress in Engineering (DCE 19)
Faculty of Engineering of University of Porto (FEUP) (Oporto, Portugal)
2019/05 Thermoreversible aqueous biphasic systems composed of protic ionic liquids for biotechnological applications 4th Meeting of Medicinal Biotechnology (MMB 2019)
School of Health of P.Porto (Oporto, Portugal)
2019/04 Antibodies from egg yolk in tablets against the flu "Science coffee" at XII National Meeting of Biochemistry Students
University of Aveiro (Aveiro, Portugal)
2019/04 LYTAG-driven purification strategies for monoclonal antibodies using quaternary amine ligands as affinity matrices PAThlestra at PATh Group/CICECO – University of Aveiro
University of Aveiro (Aveiro, Portugal)
2019/03 Biocompatible ionic-liquid-mediated recovery and purification of monoclonal antibodies from CHO cell culture supernatants V IMFAHE International Conference – International Innovation Camp
University of La Laguna (San Cristobal de La Laguna, Santa Cruz de Tenerife, Canary Islands, Spain)
2018/11 Purification platform for monoclonal antibodies based on aqueous biphasic systems formed by glycine-betaine ionic liquids XXIV Encontro Luso-Galego de Química (XXIV ELGQ)
Faculty of Sciences of University of Porto (FCUP) (Oporto, Portugal)
2018/10 Solvatochromic parameters of mixtures of ionic liquids: experimental studies and COSMO-RS prediction 27th EuCheMS Conference on Molten Salts and Ionic Liquids (EuCheMSIL 2018)
(Lisbon, Portugal)
2018/10 Recovery of value-added antibodies from serum samples 13 th International Chemical and Biological Engineering Conference (CHEMPOR 2018)
(Aveiro, Portugal)
2018/09 Recovery of immunoglobulin G from human serum using ionic-liquid-based aqueous biphasic systems 12th European Symposium on Biochemical Engineering Sciences (ESBES2018)
(Lisbon, Portugal)
2017/11 Ionic-liquid mediated extraction and purification of monoclonal antibodies from cell culture supernatants Anything But Conventional Chromatography (ABC2)
(Lisbon, Portugal)
2017/11 Remarkable platform for the separation of aromatic and aliphatic amino acid mixtures using ionic-liquid-based processes Anything But Conventional Chromatography (ABC2)
(Lisbon, Portugal)
2017/09 Factors driving solute partition in ionic-liquid-based aqueous biphasic systems Biopartitioning and Purification Conference 2017 (BPP2017)
(Copenhagen, Denmark)
2017/06 Solvatochromic parameters of deep eutectic solvents formed by ammonium-based salts and carboxylic acids PATh Spring Workshop 2017 – 2nd edition: Deep Eutectis Solvents (DES)
University of Aveiro (Aveiro, Portugal)
2017/05 Ionic-liquid-based strategies for monoclonal antibodies downstream processing II International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship - Trends in Biotechnology for Biomedical Applications (UBI-HSR 2017)
Faculty of Health Sciences of Universidade da Beira Interior (Covilhã, Portugal)
2017/04 Integration of capture and polishing of monoclonal antibodies from cell culture supernatants using ionic-liquids-based approaches V National Meeting of Chemistry Students (V ENEQUI)
University of Coimbra (Coimbra, Portugal)
2016/11 Novel Systems for the Extraction and Purification of Monoclonal Antibodies directly from CHO Cell Cultures Supernatants using Aqueous Biphasic Systems comprising Ionic Liquids International Symposium on the Separation of Proteins, Peptides and Polynucleotides 2016 (ISPPP2016)
(Salzburg, Austria)
2016/05 Selective separation of amino acids using aqueous biphasic systems composed of ionic liquids PATh Spring Workshop 2016 – 1st edition: Aqueous Biphasic Systems (ABS)
University of Aveiro (Aveiro, Portugal)
2016/05 New Insights into the Physicochemical Behaviour of Ionic-Liquid-based Aqueous Biphasic Systems PATh Spring Workshop 2016 – 1st edition: Aqueous Biphasic Systems (ABS)
University of Aveiro (Aveiro, Portugal)
2016/04 Development of Integrated Systems for Extraction and Purification of Monoclonal Antibodies directly from CHO Cell Cultures Supernatants using Aqueous Biphasic Systems composed of Ionic Liquids as Adjuvants 5th Portuguese Young Chemists Meeting and 1st European Young Chemists Meeting (5th PYCheM & 1st EYCheM)
(Guimarães, Portugal)
2016 Exploring ionic liquids for the development of a purification platform for therapeutic immunoglobulin Y (IgY) from egg yolk XXII Encontro Luso-Galego de Química (XXII ELGQ)
Instituto Politécnico de Bragança (Bragança, Portugal)
2015/03 Aqueous biphasic systems composed of ionic liquids and amino acids as remarkable selective extraction approaches III National Meeting of Chemistry Students (III ENEQUI)
University of Aveiro (Aveiro, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2024/11 - Current Purification and biological activity assessment of monoclonal antibodies
Supervisor of Ana Salgado
Universidade de Aveiro, Portugal
2024/10 - Current Purification and characterization of monoclonal antibodies
Supervisor of Luís Almeida
Universidade de Aveiro, Portugal
2024/10 - Current Purification and stability assessment of monoclonal antibodies
Supervisor of Eva Silva
Universidade de Aveiro, Portugal
2024 - Current FragmAb: Development of sustainable and cost-effective processes for the production and purification of monoclonal antibodies fragments using ionic liquid-based strategies
Supervisor of Ana Miguel da Silva Loureiro
PhD in Chemical Engineering (PhD)
Universidade de Aveiro, Portugal
2024 - Current Extraction and purification of proteins from edible insects using bio-based ionic liquids
Co-supervisor of Gabriel Silva Graça
PhD in Chemical Engineering (PhD)
Universidade de Aveiro, Portugal
2024/09 - 2024/12 Recovery of ferulic and p-coumaric acids from rice husk with ionic liquids
Co-supervisor of Mauro Rocha Lisboa
Postgraduate Traineeship in Chemical Engineering (Other)
Universidade de Aveiro, Portugal

Universidad de la República Uruguay, Uruguay

Event organisation

Event name
Type of event (Role)
Institution / Organization
2024/09/30 - 2024/10/06 Organization of the stand “InsectERA - The ERA of the insect industry” during the Aveiro TechWeek 2024. Largo Mercado Manuel Firmino, Aveiro, Portugal. (2024/09/30 - 2024/10/06)
Exhibition
2019/04/13 - 2019/04/13 Organization and mentor of the workshop "Aqueous biphasic systems constituted by ionic liquids: from the formation to the application" at "XII National Meeting of Biochemistry Students - XII ENEBIOQ" (2019/04/13 - 2019/04/13) Universidade de Aveiro, Portugal
2017/09/30 - 2018/09/15 Member of the Organizing Committee of “European Symposium on Biochemical Engineering Sciences 2018 – ESBES 2018” (2018/09/09 - 2018/09/12)
Conference (Member of the Organising Committee)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/10/12 - 2017/10/14 Organization of the stand “Spec-IgY specific chicken antibodies: a solution to save lives” during the TECHDAYS 2017 in Health area. Parque de Exposições de Aveiro, Aveiro, Portugal. (2017/10/12 - 2017/10/14)
Exhibition
2014/08/01 - 2014/09/30 Member of the Organizing Committee of “20th European Conference on Thermophysical Properties” (2014/08/31 - 2014/09/04)
Conference (Member of the Organising Committee)
Universidade do Porto Faculdade de Ciências, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2024/09/30 - 2024/09/30 Round table participation “The power of mentoring”
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Committee member

Activity description
Role
Institution / Organization
2024/10 - Current Guest Editor of the Special Issue “Development and Application of Pharmaceutical and Biotechnological Processes Based on Alternative Solvents” at Molecules (MDPI). MDPI AG, Switzerland
2024/07 - Current Guest Editor of the Special Issue “Advances in Ionic Liquids in Chemical and Biological Engineering” at Processes (MDPI). Special Issue that belongs to "Chemical Processes and Systems" section. Access link: https://www.mdpi.com/journal/processes/special_issues/090N93KKTG. MDPI AG, Switzerland

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018/06/21 - 2018/06/21 Laboratory class for the validation of an experimental protocol on the ambit of the article “A simple approach for the determination and characterization of ternary phase diagrams of aqueous two-phase systems composed of water, polyethylene glycol and sodium carbonate” Universidade de Aveiro, Portugal
2018/02/06 - 2018/02/06 Laboratory class for the validation of an experimental protocol on the ambit of the article “Aqueous Biphasic Systems in the Separation of Food Colorants” Universidade de Aveiro, Portugal
2017/09 - 2018/02 Microbial Biotechnology (1st semester, 4h per week) 3rd year of the degree in Biotechnology (Licenciatura) Department of Chemistry, University of Aveiro, Portugal, Portugal
2017/02/07 - 2017/02/10 Trainer at Ionic Liquids Winter School (ILWS) Universidade do Porto Faculdade de Ciências, Portugal

Evaluation committee

Activity description
Role
Institution / Organization Funding entity
2024/09 - 2024/11 Permanent member of the jury for the attribution of 1 Research Fellowship at CICECO – Aveiro Institute of Materials, University of Aveiro, Portugal (Reference: 105/2024/BI/AgendasPRR).
Member
Universidade de Aveiro, Portugal
2021 - 2021 Student External Expert/Consultant at Agency for Assessment and Accreditation of Higher Education (A3ES) – member of the External Evaluation Committee for the evaluation of PhD cycles
Evaluator
Agência De Avaliação E Acreditação Do Ensino Superior, Portugal

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2023/02 Scientific article highlighted at UAveiro Research Newsletter #321 – “Supported ionic liquids as customizable materials to purify immunoglobulin G”, EV Capela, J Bairos, AQ Pedro, MC Neves, MR Aires-Barros, AM Azevedo, JAP Coutinho, APM Tavares, MG Freire, Separation and Purification Technology, 305, 2023. UAveiro Research Newsletter #321
2019/04 Several mediatic highlights (80+) – “Egg yolk antibodies in tablets against the flu”, research of Emanuel V. Capela and team highlighted in websites, newspapers, magazines, radios and TV news. SIC, TVI, Porto Canal, Diário de Notícias, among others

Interview (tv / radio show)

Program Topic
2019/07/19 - 2019/07/19 90 segundos de ciência - Antena 1 Ep. 671 Emanuel Capela – E se em vez de uma injeção a vacina da gripe viesse numa pastilha?
2019/04/04 - 2019/04/04 Jornal Nacional - TVI Anticorpos da gema de ovo em pastilhas contra a gripe
2017/06/10 - 2017/06/10 Click - Antena 1 Investigador da UA usa líquidos iónicos para separar 2 classes de aminoácidos

Journal scientific committee

Journal title (ISSN) Publisher
2024 - Current Chemical Engineering Journal (1873-3212) Elsevier
2024 - Current Journal of Molecular Liquids (0167-7322) Elsevier
2024 - Current ChemEngineering (2305-7084) MDPI
2020 - Current Current Research in Nutrition and Food Science Journal (2322-0007) Enviro Research Publishers
2020 - Current Biochemical Engineering Journal (1369-703X) Elsevier
2019 - Current Oriental Journal Of Chemistry (2231-5039) Oriental Scientific Publishing Company
2018 - Current Korean Journal of Chemical Engineering (1975-7220) Springer-Verlag
2017 - Current Separation and Purification Technology (1383-5866) Elsevier

Mentoring / Tutoring

Topic Student name
2024/03 - Current Development of a sustainable technology to extract and purify proteins from insects using bio-based ionic liquids Pedro Daniel Ribeiro da Silva Moleiro
2024/03 - Current RemAb: Reshaping mAbs biomanufacturing with ionic liquids João Vasco Almeida Silva Valente
2024/03 - 2024/10 Sustainable technology to extract and purify proteins from insects using deep eutectic solvents Güliz Akyüz
2020/09 - 2021/07 Development of photoresponsive aqueous biphasic systems Ana Beatriz Lopes Fonseca
2019/09 - 2021/02 Removal of albumin from platelet lysates for the fabrication of hydrogels for 3D cell culture Ana Miguel da Silva Loureiro
2020/02 - 2020/12 Three-phase partitioning systems as alternative platforms for the purification of human antibodies Ilaria Magnis
2019/09 - 2020/12 Integrated process for the production and purification of antibodies fragments Andreia Sofia Gomes Correia
2020/03 - 2020/07 Purification of monoclonal antibodies using centrifugal partition chromatography Rúben Daniel Lopes Alves
2020/02 - 2020/07 Stabilization of nucleic acids using ionic liquids and deep eutectic solvents Jéssica Santinha Almeida
2020/02 - 2020/07 Stabilization of proteins using ionic liquids and deep eutectic solvents Ana Margarida Carrilho Loureiro
2019/09 - 2020/07 Purification of therapeutic antibodies from human serum using pear graphene aerogels Ana Beatriz Lopes Fonseca
2018/09 - 2020/07 Purification of therapeutic monoclonal antibodies using biocompatible ionic liquids Alexandre Filipe Ereira Santiago
2018/09 - 2020/03 Microplastics in the indoor environment João Vasco Almeida Silva Valente
2019/09 - 2020/02 Purification of monoclonal antibodies using centrifugal partition chromatography Rúben Daniel Lopes Alves
2019/10 - 2019/12 Application of newly synthesized ionic liquids for pharmaceuticals extraction Bojan Kopilovic
2019/04 - 2019/12 Correlations between laccase activity in ionic liquids and their COSMO-RS descriptors João Cláudio Nunes
2018/09 - 2019/12 Production and purification of anti-human interleukin-8 monoclonal antibodies Jéssica Chaves Braga Bairos
2019/02 - 2019/07 Application of newly synthesized ionic liquids for pharmaceuticals extraction Bojan Kopilovic
2019/02 - 2019/07 Purification of therapeutic antibodies from human serum using pear graphene aerogels Ana Beatriz Lopes Fonseca
2019/02 - 2019/07 Development of thermoreversible aqueous biphasic systems for the processing of biopharmaceuticals Rafael Gonçalves Silva
2018/11 - 2019/07 Carbon xerogels as novel separation matrices for monoclonal antibodies purification Bruno José Carvalho
2018/10 - 2019/04 Laccase extraction and activity enhancement using ionic liquid-based aqueous biphasic systems Ana Isabel Valente
2018/11 - 2019/01 Stability assessment of human antibodies in ionic-liquid-based formulations Filipa Oliveira
2018/11 - 2019/01 Pear graphene aerogels as novel separation matrices for monoclonal antibodies purification Fabiana Pereira
2018/07 - 2018/09 Stability assessment of human antibodies in aqueous solutions of ionic liquids Andreia Reis Louro
2018/04 - 2018/08 Double-switchable aqueous biphasic systems Ana Filipa Correia Santos Rufino
2018/01 - 2018/07 Purification of therapeutic monoclonal antibodies using alternative platforms Alexandre Filipe Ereira Santiago
2017/07 - 2017/08 Production and bioprocess development for the downstream processing of monoclonal antibodies Tiago Porfírio Santos
2016/09 - 2017/07 Extraction and purification of immunoglobulin G using aqueous biphasic systems constituted by ionic liquids as adjuvants Ana Paula Dias Amorim

Other jury / evaluation

Activity description Institution / Organization
2024/07/18 - Current Examiner – “PhD Thesis Project Preparation”. João Luís Pereira Fernandes, “Customized ionic liquid patches for efficient and non-invasive transdermal delivery of messenger RNA vaccines”, PhD Thesis in Chemical Engineering, University of Aveiro (in collaboration with RYAPURTECH, LDA), Portugal. Universidade de Aveiro, Portugal
Distinctions

Award

2019 2nd award in “II IMFAHE's Ideas Competition – Nodal Award/Shark Tank Edition”
International Mentoring Foundation For The Advancement Of Higher Education (IMFAHE), United States
2018 Honorable mention to poster presentation in the event “X Biochemistry Day”
Universidade de Aveiro, Portugal
2017 FCT PhD Grant (SFRH/BD/126202/2016) in the “Bioengineering and Biotechnology” panel
Fundação para a Ciência e a Tecnologia, Portugal
2017 1st Place at ABC2 Conference Contest for Young Researchers
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017 MICROBIOTEC´17 Attendance Grant
Sociedade Portuguesa de Biotecnologia, Portugal
2016 Best Poster Award on the event “IV National Meeting of Chemistry Students”
Universidade do Porto Faculdade de Ciências, Portugal
2016 Merit Award – curricular year 2015/2016 (Final grade: 19.6 out of 20)
Direção-Geral do Ensino Superior (DGES), Portugal
2011 Diploma of Merit 2010/2011
Escola Secundária de Esmoriz, Portugal
2011 Best student admitted in the Bachelor in Biochemistry (Entry grade: 19 out of 20)
Universidade de Aveiro, Portugal
2010 Diploma of Merit 2009/2010
Escola Secundária de Esmoriz, Portugal
2009 Diploma of Merit 2008/2009
Escola Secundária de Esmoriz, Portugal

Other distinction

2020 Santander - IE Digital Revolution Program Scholarship
Banco Santander Totta, Portugal
2019 Themed collection “2018 PCCP HOT Articles”: Physical Chemistry Chemical Physics 20 (2018) 8411-8422
Royal Society of Chemistry, United Kingdom
2019 Certificate of Excellence, Entrepreneurship and Innovation at “V IMFAHE International Conference – International Innovation Camp”
International Mentoring Foundation For The Advancement Of Higher Education (IMFAHE), United States
2019 Themed collection “PCCP Perspectives”: Physical Chemistry Chemical Physics 20 (2018) 8411-8422
Royal Society of Chemistry, United Kingdom
2018 Certificate of Outstanding Contribution in Reviewing in recognition of the contributions made to the quality of the journal Separation and Purification Technology (Elsevier)
Elsevier Inc, United States
2018 Themed collection “Celebrating Excellence in Research: 100 Women of Chemistry”: Green Chemistry 19 (2017) 1850-1854
Royal Society of Chemistry, United Kingdom
2018 Featured as a content highlight in the PCCP promotional flyer: Physical Chemistry Chemical Physics 20 (2018) 8411-8422
Royal Society of Chemistry, United Kingdom
2017 Certificate of Reviewing in recognition of the review made for the journal Separation and Purification Technology (Elsevier)
Elsevier Inc, United States
2017 Themed collection “2017 Green Chemistry Hot Articles”: Green Chemistry 19 (2017) 1850-1854
Royal Society of Chemistry, United Kingdom
2017 Green Chemistry Back Cover: Green Chemistry 19 (2017) 2018-2018
Royal Society of Chemistry, United Kingdom
2017 Most Downloaded Fluid Phase Equilibria Articles: Fluid Phase Equilibria 448 (2017) 15-21
Elsevier Inc, United States