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Mestre em Engenharia Biomédica pela Universidade do Porto, desenvolvo trabalho cientifico na área de neurociências humanas recorrendo a técnicas de imagem, nomeadamente ressonância magnética estrutural e funcional, tomografia por emissão de positrões e tomografia de coerência óptica. Nos últimos anos o meu trabalho tem sido desenvolvido no CIBIT (Coimbra Institute for Biomedical Imaging and Translational Research) e no ICNAS (Instituto de Ciências Aplicadas à Saúde) - Universidade de Coimbra - com grande foco no envelhecimento e patologias que lhes estão associadas, acedendo às alterações cerebrais estruturais, funcionais e moleculares bem como às alterações estruturais da retina.
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Identification

Personal identification

Full name
Lília Jorge

Citation names

  • Jorge, Lília

Author identifiers

Ciência ID
1411-F695-C78F
ORCID iD
0000-0001-7683-2987

Email addresses

  • liliajorge@uc.pt (Professional)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Engineering and Technology - Medical Engineering
  • Medical and Health Sciences - Clinical Medicine - Radiology, Nuclear Medicine and Medical Imaging
  • Exact Sciences - Mathematics - Statistics and Probability

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Advanced (C1) Upper intermediate (B2) Advanced (C1) Advanced (C1)
Spanish; Castilian Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Education
Degree Classification
2021/01/01 - 2025/01/01
Ongoing
 Engenharia Biomédica (Doutoramento)
Major in Neurociências
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Neurobiological Mechanisms of Aging in Down syndrome" (THESIS/DISSERTATION)
2011/09/19 - 2013/10/25
Concluded
 Engenharia Biomédica (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
"Acelerometria na Reabilitação do membro superior Após-AVC. " (THESIS/DISSERTATION)
 14
2007/09/24 - 2010/09/18
Concluded
 Engenharia Biomédica (Licenciatura)
Instituto Politécnico do Porto, Portugal
 14
Affiliation

Science

Category
Host institution 		Employer
2018/01/29 - 2020/12/31 Science and Technology Management Universidade de Coimbra, Portugal
Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal
(...)
2015/07/01 - 2017/12/31 Researcher (Research) Universidade de Coimbra, Portugal
CNC.IBILI, Portugal
2014/07/01 - 2015/06/30 Researcher (Research) Universidade de Coimbra, Portugal
IBILI (Instituto Biomédico de Investigação da Luz e da Imagem), Portugal

Others

Category
Host institution 		Employer
2021/01/01 - Current PhD student Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal
(...)
Projects

Grant

Designation Funders
2021/01/01 - 2024/12/31 Neurobiological Mechanisms of Aging in Down syndrome
2020.08187.BD
10.54499/2020.08187.BD
PhD Student Fellow
Universidade de Coimbra Centro de Imagem Biomédica e Investigação Translacional, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal

Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/01/29 - 2020/12/31 BIGDATIMAGE – “From computational modelling and clinical research to the development of neuroimaging big data platforms for discovery of novel biomarker.
CENTRO-01-0145-FEDER-000016
Science and Technology Management Fellow
Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal
Ongoing
2015/07/01 - 2017/12/31 Trabalho multidisciplinar no âmbito de imagiologia estrutural da retina e do cérebro e classificação estatística dos dados em doenças da retina.
UID/NEU/04539/2013
Research Fellow
CNC.IBILI, Portugal
Concluded
2014/07/01 - 2015/06/30 From molecules to man: novel diagnostic imaging tools in neurological and psychiatric disorders.
CENTRO-07-ST24-FEDER-00205
Research Fellow
CNC.IBILI, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2015/05/01 - Current The UK GENetic Frontotemporal dementia Initiative (UK GENFI).
info:eu-repo/grantAgreement/RCUK/MRC/MR2%FM0236642%F1/GB
Researcher
UK Research and Innovation
2016/07/01 - 2018/12/31 The changing brain in Alzheimer’s disease: is the retina a reliable mirror of disease onset and progression? Mantero Belard Award - Santa Casa Awards – Neurosciences (3rd edition), Santa Casa da Misericórdia de Lisboa (2016-2018).
MB-1049-2015
Researcher
CNC.IBILI, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal
Santa Casa da Misericórdia de Lisboa
Concluded
Outputs

Publications

Book chapter
  1. Bernardes, R.; Jorge, Lília; Nunes, Ana; Castelo-Branco, Miguel. "Machine Learning Approaches in OCT: Application to Neurodegenerative Disorders". In OCT and Imaging in Central Nervous System Diseases, 507-521. Springer International Publishing, 2020.
    Published
Conference abstract
  1. Jorge, Lília; Canário, Nádia; Quental, Hugo; Bernardes, R.; Castelo-Branco, Miguel. "Retina, a Mirror of the Brain: an Association Between Macular and Cerebral Structural Integrity over Age". Paper presented in EVER 2018 Congress, Nice, 2018.
    Published • 10.1111/aos.13972_209
  2. Castelo-Branco, Miguel; Jorge, Lília; Alves, Carolina; Canário, Nádia; Santiago, Beatriz; Santana, Isabel; Quental, Hugo; Reis, Aldina; Ambrósio, A.F.. "Inner Retinal Layers of the Retina Predict Visual Cortical Thickness and Structural Connectivity in Early Alzheimer's Disease". Paper presented in EVER 2018 Congress, Nice, 2018.
    Published • 10.1111/aos.13972_61
Conference poster
  1. Silva, M.F.; Jorge, Lília; Canário, Nádia; Castelo-Branco, Miguel; Harvey, B. M. "Population receptive field size and visual field maps changes across human early visual cortex in healthy ageing". Paper presented in Ageing: models, mechanisms and therapies - Faculty of Medicine, University of Coimbra, 2019.
  2. Loureiro, M.F; Maruta, Carolina; Canário, Nádia; Jorge, Lília; Ferreira, Carlos; de Mendonça, Alexandre; Castelo-Branco, Miguel. "Face processing system in frontotemporal lobar degeneration: an fMRI study". Paper presented in VII Annual Meeting of IBILI - Faculty of Medicine University of Coimbra, 2015.
Journal article
  1. Jorge, Lília; Canário, Nádia; Martins, Ricardo; Santana, Isabel; Castelo-Branco, Miguel. "Dual PET-fMRI reveals a link between neuroinflammation, amyloid binding and compensatory task-related brain activity in Alzheimer’s disease". Communications Biology 5 1 (2022): http://dx.doi.org/10.1038/s42003-022-03761-7.
    10.1038/s42003-022-03761-7
  2. Bourbon-Teles, José; Jorge, Lília; Canário, Nádia; Castelo-Branco, Miguel. "Structural impairments in hippocampal and occipitotemporal networks specifically contribute to decline in place and face category processing but not to other visual object categories in healthy aging". Brain and Behavior 11 8 (2021): http://dx.doi.org/10.1002/brb3.2127.
    10.1002/brb3.2127
  3. Canário, Nádia; Jorge, Lília; Castelo-Branco, Miguel. "Distinct mechanisms drive hemispheric lateralization of object recognition in the visual word form and fusiform face areas". Brain and Language 210 (2020): http://dx.doi.org/10.1016/j.bandl.2020.104860.
    Published • 10.1016/j.bandl.2020.104860
  4. Jorge, Lília; Canário, Nádia; Martins, Ricardo; Santiago, Beatriz; Santana, Isabel; Quental, Hugo; Ambrósio, Francisco; Bernardes, Rui; Castelo-Branco, Miguel. "The Retinal Inner Plexiform Synaptic Layer Mirrors Grey Matter Thickness of Primary Visual Cortex with Increased Amyloid ß Load in Early Alzheimer’s Disease". Neural Plasticity 2020 (2020): 1-11. http://dx.doi.org/10.1155/2020/8826087.
    Published • 10.1155/2020/8826087
  5. Jorge, Lília. "Investigating the spatial correlations between Aß deposition, gray matter volume and neuroinflammation in Alzheimer's disease". Journal of Alzheimer's disease (2020):
    Under revision
  6. Bourbon-Teles, José; Canário, Nádia; Jorge, Lília; Castelo-Branco, Miguel. "Frontoparietal microstructural damage mediates age-dependent working memory decline in face and body information processing: evidence for dichotomic hemispheric bias mechanisms". Neuropsychologia (2020):
    Submitted
  7. Jorge, Lília; Canário, Nádia; Quental, Hugo; Bernardes, R.; Castelo-Branco, Miguel. "Is the Retina a Mirror of the Aging Brain? Aging of Neural Retina Layers and Primary Visual Cortex Across the Lifespan". Frontiers in Aging Neuroscience 11 360 (2020): http://dx.doi.org/10.3389/fnagi.2019.00360.
    Published • 10.3389/fnagi.2019.00360
  8. Alves, Carolina; Jorge, Lília; Canário, Nádia; Santiago, Beatriz; Santana, Isabel; Castelhano, João; Ambrósio, António Francisco; Bernardes, Rui; Castelo-Branco, Miguel. "Interplay Between Macular Retinal Changes and White Matter Integrity in Early Alzheimer’s Disease". Journal of Alzheimer's Disease 70 3 (2019): 723-732. http://dx.doi.org/10.3233/jad-190152.
    Published • 10.3233/jad-190152
  9. Jorge, Lília; Canário, Nádia; Castelhano, João; Castelo-Branco, Miguel. "Processing of performance-matched visual object categories: faces and places are related to lower processing load in the frontoparietal executive network than other objects". European Journal of Neuroscience 47 8 (2018): 938-946. http://dx.doi.org/10.1111/ejn.13892.
    Published • 10.1111/ejn.13892
  10. Jorge, Lília (shared first authorship); Canário, Nádia; Loureiro Silva, M.F.; Alberto Soares, Mário; Castelo-Branco, Miguel. "Distinct preference for spatial frequency content in ventral stream regions underlying the recognition of scenes, faces, bodies and other objects". Neuropsychologia 87 (2016): 110-119. http://dx.doi.org/10.1016/j.neuropsychologia.2016.05.010.
    Published • 10.1016/j.neuropsychologia.2016.05.010
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2018/10/05 Retina, a Mirror of the Brain: an Association Between Macular and Cerebral Structural Integrity over Age EVER congress 2018
(Nice, France)
Distinctions

Award

2018 Primeiro lugar no 2.º Concurso Nacional de Fotografia SIGMA, na categoria "Wild Life" - os animais no seu habitat natural.
COMERCIALFOTO, Portugal
2018 Best Poster Award (Neuro-opthalmology) at the European Congress - European Association for Vision and Eye Research
European Association for Vision and Eye Research (EVER) , France