Fernanda Marujo Marques (1C11-A0C7-418A)

Curriculum Vitae

Fernanda Marujo Marques

Fernanda Marujo Marques is Principal Researcher at Instituto Superior Técnico (IST), Universidade de Lisboa (ULisboa). She is a Chemical Engineer from IST (1978) and has a PhD in Biochemistry (1993) from Faculdade de Ciências, ULisboa. She has so far 134 papers in international peer review journals and more than 100 presentations at national and international conferences. She participated in 16 research projects. She started her professional career as Chemical Engineer at Instituto Hidrográfico (Portuguese Navy) (1980-1982) in Analytical Chemistry under the scope of Marine Sciences for protection and preservation of marine environment. She was Trainee Researcher (December 1982-April 1985), and Assistant Researcher (April 1985-October 1994) at Laboratório Nacional de Engenharia e Tecnologia Industrial (LNETI). During this period, her research work was centered in the production of radionuclides at the Portuguese Research Reactor (RPI) (e.g., 198Au, 103Pd, 153Sm, 166Ho, 177Lu, 64Cu) for therapeutic applications. She was trained in the development of radioimmunoassays (RIA) for T3 and T4 hormones in the diagnosis of thyroid diseases in International Centers, the Institute of Isotopes at the Hungarian Academy of Sciences, Budapest (1987) and NETRIA St Bartholomew's Hospital, London (1989). She was responsible for the supply of T3 and T4 “kits” to Nuclear Medicine Centers (1982-1995), namely Instituto Português de Oncologia (IPO) and Stª Maria Hospital/Faculdade de Medicina de Lisboa. She did her PhD at Faculdade de Medicina, ULisboa, Instituto Química Fisiológica (1987-1993) in the area of Biochemistry, on redox mechanisms at the erythrocyte membrane mediated by catecholamines and got the PhD from Faculdade de Ciências, ULisboa (November 1993). Since October 1994 she was Auxiliary Researcher at Instituto Tecnológico e Nuclear (ex-LNETI). Under the scope of her Thesis, she published 7 papers in international refereed Journals. She was in charge of Laboratório Central de Análises (LCA), UAveiro as Executive Director (1994-1998). During this period, she did the installation and technical support during installation of the Laboratory, setup of laboratory equipment and instruments and was responsible for the analytical services. She receive training in analytical chemistry, elemental analysis by ICP (inductively coupled plasma) and X-ray fluorescence spectrometry and isotopic analysis by mass spectrometry (MS) in geological dating (87Sr/86Sr). She also receive training by RELACRE-Associação Laboratórios Acreditados de Portugal to the implementation of a Quality System for Elemental Analysis. Since 1998, the scientific activity developed has been centered in several domains. In the scope of nuclear techniques and radiochemistry, she developed methodologies for the labelling of molecules with radionuclides (e.g., 198/199Au, 99mTc, 188Re and radiolanthanides) and to assess their potential as diagnostic/therapeutic agents. Under the scope of these scientific domains, she published ca. 22 papers in international refereed Journals. She pioneer in Portugal the development of estrogen receptor binding assays (RBA), using human ER alpha/beta protein recombinant, to evaluate the potential of estrogen derivatives as diagnostic/therapeutic agents for breast cancer. Under the scope of these scientific domains, and the project Cimago, UCoimbra, she published 7 papers in international refereed Journals. In the domain of Medicinal Chemistry, she has been involved with the biological evaluation of metal-based complexes as anticancer and antimicrobial agents. Under this scope, she published ca. 90 papers in international refereed Journals. In the domain of radiation techniques, and in particular radiosensitizers in Radiation Oncology making use of neutrons, gamma rays and proton beams she published ca. 7 papers in international refereed Journals.

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Identification

Personal identification

Full name: Fernanda Marujo Marques

Citation names

Marques, Fernanda
Waerenborgh, Fernanda

Author identifiers

Ciência ID: 1C11-A0C7-418A
ORCID iD: 0000-0001-8440-5299
Researcher Id: J-9790-2013
Scopus Author Id: 16402591700

Telephones

Mobile phone

966226528 (Personal)

Telephone

219946225 Ext.: 6225 (Professional)

Addresses

Instituto Superior Técnico, Campus Tecnológico e Nuclear EN 10, Km 139.7, 2695-066, Bobadela, Loures, Loures, Portugal (Professional)
Rua Padre Américo, 31 4ºA, 1600-548, Lisboa, Lisboa, Portugal (Personal)

Knowledge fields

Exact Sciences - Chemical Sciences - Nuclear Chemistry
Medical and Health Sciences - Health Sciences
Medical and Health Sciences - Health Sciences
Natural sciences - Biological Sciences - Biochemistry
Exact Sciences - Chemical Sciences - Nuclear Chemistry
Exact Sciences - Chemical Sciences - Analytical Chemistry
Medical and Health Sciences - Basic Medicine - Medicinal Chemistry
Medical and Health Sciences - Basic Medicine - Medicinal Chemistry

Languages

Language	Speaking	Reading	Writing	Listening
English	Intermediate (B1)	Advanced (C1)	Intermediate (B1)	Intermediate (B1)
French	Intermediate (B1)	Advanced (C1)	Beginner (A1)	Intermediate (B1)
Spanish; Castilian	Beginner (A1)	Advanced (C1)	Beginner (A1)	Beginner (A1)
Arab	Beginner (A1)	Beginner (A1)	Beginner (A1)	Beginner (A1)

Education

	Degree	Classification
1987/04 - 1993/11 Concluded	n/a (Doutoramento) Major in Bioquímica Universidade de Lisboa Faculdade de Medicina, Portugal "Contribuição para o Estudo de Fenómenos Redox na Membrana Citoplasmática Modificados pelas Catecolaminas" (THESIS/DISSERTATION)	Magna cum Laude
1978 Concluded	Engenharia Química (ramo Tecnologia) (Licenciatura) Universidade de Lisboa Instituto Superior Técnico, Portugal "n/a" (THESIS/DISSERTATION)	14/20

Affiliation

Science

	Category Host institution	Employer
2012 - Current	Auxiliary Researcher (Research)	Universidade de Lisboa Departamento de Engenharia e Ciências Nucleares, Portugal

1998/11/01 - 2012	Auxiliary Researcher (Research)	Instituto Tecnológico e Nuclear Departamento de Radioisótopos, Portugal

1985/04/01 - 1994/10/01	Research Assistant (Research)	Laboratório Nacional de Engenharia e Tecnologia Industrial , Portugal

Other Careers

	Category Host institution	Employer
1980/09 - 1982/12	Técnico Superior (Técnico Superior)	Instituto Hidrográfico, Portugal
	Instituto Hidrográfico, Portugal

Others

	Category Host institution	Employer
1994/09/01 - 1998/11/01	Executive Director of Laboratório Central de Análises	Universidade de Aveiro, Portugal

1982/12/01 - 1985/04/01	Trainee Researcher	Laboratório Nacional de Engenharia e Tecnologia Industrial , Portugal

Projects

Contract

	Designation	Funders
2023/05 - Current	Sub-cellular Imaging and Irradiation using Accelerator-based Techniques CRP-F11024 Researcher International Atomic Energy Agency, Austria	Ongoing
2021/01/01 - 2023/06/30	TOF-PET for Proton Therapy (TPPT) .: In-beam Time-of-Flight (TOF) Positron Emission Tomography (PET) for proton radiation therapy LISBOA-01-0247-FEDER-045904 Researcher Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal	Concluded
2022/04 - 2023/06	Theranostic strategy for proton boron capture therapy of pancreatic cancer UTAP-EXPL/FMT/0020/2021 Researcher Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal	Concluded
2021/03 - 2022/12	Ruthenium-peptide conjugates: arrows for selectively targeting breast cancer PTDC/QUI-QIN/0146/2020 Researcher Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal	Ongoing
2018/09/01 - 2021/08/31	Nanopartículas Multifuncionais para Quimioradioterapia do Glioblastoma PTDC/MED-QUI/29649/2017 Researcher Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal Universidade da Beira Interior, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2013/06/01 - 2016/11/30	Sistemas Moleculares e Nano para Teranóstica de Cancro EXCL/QEQ-MED/0233/2012 Researcher Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal Universidade de Aveiro, Portugal Universidade de Coimbra, Portugal Instituto de Medicina Molecular, Portugal Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2012/03/01 - 2015/08/31	Avaliação pré-clínica de potenciais fármacos de Ruténio na terapia do cancro PTDC/QUI-QUI/118077/2010 Researcher Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal Universidade de Lisboa Faculdade de Ciências, Portugal Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011/04/04 - 2014/10/02	Síntese e Avaliação Pré-Clínica de Complexos de Indio Derivados do Estradiol para Radioterapia Tumoral PTDC/QUI-QUI/111891/2009 Researcher Universidade de Lisboa Instituto Superior Técnico, Portugal Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011/03/01 - 2014/02/28	Síntese, Caracterização e Avaliação Biológica de Compostos Multifuncionais Osteotrópicos PTDC/QUI-QUI/115712/2009 Researcher Universidade de Lisboa Instituto Superior Técnico, Portugal Instituto de Medicina Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/01/01 - 2013/06/30	Complexos de Ruténio para aplicação anti-tumoral PTDC/QUI-QUI/101187/2008 Researcher Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal Universidade de Lisboa Faculdade de Ciências, Portugal Universidade de Lisboa Instituto Superior Técnico, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2009/01/01 - 2012/10/31	Estudos Químicos, Radioquímicos e Biológicos de Complexos de Pt (II) com Ligandos Pirazolo-Alquilamina: Aplicações no Desenvolvimento de Novos Agentes Anti-cancerígenos PTDC/QUI/66813/2006 Researcher Universidade de Lisboa Instituto Superior Técnico, Portugal Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2008 - 2012	Chemical, Radiochemical and Biological Studies of Pyrazolyl-Alkylamine Pt(II) Complexes: Application on the Development of Novel Anti-cancer Drugs info:eu-repo/grantAgreement/FCT/3599-PPCDT/66813/PT Researcher Universidade de Lisboa Instituto Superior Técnico, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2005 - 2008	Novel estrogen receptor ligands as potential probes for targeted tumor imaging and therapy CIMAGO/FLAD/09/05 Researcher Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal	Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia Concluded
2005/10/01 - 2007/12/31	Complexos Multifuncionais de Tecnécio e Gálio para Radioterapia Selectiva POCI/QUI/57632/2004 Researcher Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2002/03/01 - 2005	Radiopharmaceuticals for treatment of bone cancer pain and/or therapy based on macrocyclic lanthanide complexes. info:eu-repo/grantAgreement/FCT/POCI/35859/PT Researcher Instituto Tecnológico e Nuclear Departamento de Radioisótopos, Portugal	Universidade do Algarve Faculdade de Ciências e Tecnologia Concluded
2002 - 2004	Quality of skin as a barrier to ultra-fine particles (NANODERM) EC shared COST RTD ACTION: QoL Researcher Instituto Tecnológico e Nuclear Departamento de Radioisótopos, Portugal	Concluded
2000/11/01 - 2003/11	Evaluation of the genotoxic and antiestrogenic potential of triphenylethylene derivatives and their metabolites info:eu-repo/grantAgreement/FCT/POCI/33544/PT Researcher Instituto Tecnológico e Nuclear Departamento de Radioisótopos, Portugal	Universidade do Algarve Faculdade de Ciências e Tecnologia

Outputs

Publications

Book chapter	Marques, Fernanda. "Ruthenium-based anticancer compounds: insights into their cellular targeting and mechanism of action". 2017.
Journal article	Teresa Pinheiro; Luís C Alves; António P Matos; Isabel Correia; João Costa Pessoa; Fernanda Marques. "Cellular targets of cytotoxic copper phenanthroline complexes: a multimodal imaging quantitative approach in single PC3 cells". Metallomics (2024): https://doi.org/10.1093/mtomcs/mfae051. 10.1093/mtomcs/mfae051 Joana P. Costa; Sílvia A. Sousa; Jorge H. Leitão; Fernanda Marques; Marta M. Alves; M. Fernanda N. N. Carvalho. "Insights into the Dual Anticancer and Antibacterial Activities of Composites Based on Silver Camphorimine Complexes". Journal of Functional Biomaterials (2024): https://doi.org/10.3390/jfb15090240. 10.3390/jfb15090240 João Franco Machado; Marco Sá; Inês Pires; Miguel Tarita da Silva; Fernanda Marques; Jaime A. S. Coelho; Filipa Mendes; et al. "Dual FGFR-targeting and pH-activatable ruthenium–peptide conjugates for targeted therapy of breast cancer". Dalton Transactions (2024): https://doi.org/10.1039/D4DT00497C. 10.1039/D4DT00497C Constantin Vitré; Yann Le Gal; Antoine Vacher; Thierry Roisnel; Dominique Lorcy; Sofia Santana; Miguel Prudêncio; Teresa Pinheiro; Fernanda Marques. "Structure–activity relationship of anticancer and antiplasmodial gold bis(dithiolene) complexes". Dalton Transactions (2024): https://doi.org/10.1039/D4DT01458H. 10.1039/D4DT01458H Laura Gutiérrez-Gálvez; Tania García-Mendiola; Encarnación Lorenzo; Miquel Nuez-Martinez; Carmen Ocal; Shunya Yan; Francesc Teixidor; et al. "Compelling DNA intercalation through ‘anion–anion’ anti-coulombic interactions: boron cluster self-vehicles as promising anticancer agents". Journal of Materials Chemistry B (2024): https://doi.org/10.1039/D4TB01177E. 10.1039/D4TB01177E Andres Alguacil; Franco Scalambra; Antonio Romerosa; Andreia Bento-Oliveira; Fernanda Marques; Ines Maximiano; Rodrigo F. M. de Almeida; et al. "Evaluation of the Antiproliferative Properties of CpRu Complexes Containing N-Methylated Triazaphosphaadamantane Derivatives". Bioinorganic Chemistry and Applications (2023): https://doi.org/10.1155/2023/6669394. 10.1155/2023/6669394 Joana F. Santos; Raquel Azevedo; Miguel Prudêncio; Fernanda Marques; Yann Le Gal; Dominique Lorcy; Célia Fernandes. "Block Copolymer Micelles Encapsulating Au(III) Bis(Dithiolene) Complexes as Promising Nanostructures with Antiplasmodial Activity". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15031030. 10.3390/pharmaceutics15031030 Ana F. Amendoeira; André Luz; Ruben Valente; Catarina Roma-Rodrigues; Hasrat Ali; Johan E. van Lier; Fernanda Marques; Pedro V. Baptista; Alexandra R. Fernandes. "Cell Uptake of Steroid-BODIPY Conjugates and Their Internalization Mechanisms: Cancer Theranostic Dyes". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24043600. 10.3390/ijms24043600 Andreia Sousa; Joana F. Santos; Francisco Silva; Sousa SA; Jorge H. Leitão; António P. Matos; Teresa Pinheiro; et al. "Antitumoral and Antimicrobial Activities of Block Copolymer Micelles Containing Gold Bisdithiolate Complexes". Pharmaceutics (2023): https://www.mdpi.com/1999-4923/15/2/564. 10.3390/pharmaceutics15020564 Fanica Balanescu; Andreea Veronica Botezatu; Fernanda Marques; Anna Busuioc; Olivian Marincas; Costel Vînatoru; Geta Cârâc; Bianca Furdui; Rodica Mihaela Dinica. "Bridging the Chemical Profile and Biological Activities of a New Variety of Agastache foeniculum (Pursh) Kuntze Extracts and Essential Oil". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24010828. 10.3390/ijms24010828 Dömötör, Orsolya; Teixeira, Ricardo G.; Spengler, Gabriella; Avecilla, Fernando; Marques, Fernanda; Lenis-Rojas, Oscar A.; Matos, Cristina P.; et al. "Ruthenium(II) polypyridyl complexes with benzothiophene and benzimidazole derivatives: Synthesis, antitumor activity, solution studies and biospeciation". Journal of Inorganic Biochemistry 238 (2023): 112058. http://dx.doi.org/10.1016/j.jinorgbio.2022.112058. 10.1016/j.jinorgbio.2022.112058 Silva, Francisco; Mendes, Carolina; D'Onofrio, Alice; Campello, Maria Paula Cabral; Marques, Fernanda; Pinheiro, Teresa; Gonçalves, Kyle; et al. "Image-Guided Nanodelivery of Pt(IV) Prodrugs to GRP-Receptor Positive Tumors". Nanotheranostics 7 1 (2023): 22-40. http://dx.doi.org/10.7150/ntno.78807. 10.7150/ntno.78807 Leon F. Richter; Fernanda Marques; João D. G. Correia; Alexander Pöthig; Fritz E. Kühn. "Exploiting click-chemistry: backbone post-functionalisation of homoleptic gold(i) 1,2,3-triazole-5-ylidene complexes". Dalton Transactions (2023): https://doi.org/10.1039/D3DT03052K. 10.1039/D3DT03052K Ana Belchior; Ana Fernandes; Maxime Lamotte; Andreia Filipa Ferreira Silva; Raquel S. G. R. Seixas; Artur M. S. Silva; Fernanda Marques. "Exploring the Physical and Biological Aspects of BNCT with a Carboranylmethylbenzo[b]acridone Compound in U87 Glioblastoma Cells". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms232314929. 10.3390/ijms232314929 Tânia S. Morais; Fernanda Marques; Paulo J. Amorim Madeira; Maria Paula Robalo; Maria Helena Garcia. "Design and Anticancer Properties of New Water-Soluble Ruthenium–Cyclopentadienyl Complexes". Pharmaceuticals (2022): https://doi.org/10.3390/ph15070862. 10.3390/ph15070862 Joana P. Costa; Teresa Pinheiro; Maria S. Martins; M. Fernanda N. N. Carvalho; Joana Feliciano; Jorge H. Leitão; R. A. L. Silva; et al. "Tuning the Biological Activity of Camphorimine Complexes through Metal Selection". Antibiotics (2022): https://www.mdpi.com/2079-6382/11/8/1010. 10.3390/antibiotics11081010 Yann Le Gal; Agathe Filatre-Furcate; Dominique Lorcy; Olivier Jeannin; Thierry ROISNEL; Vincent Dorcet; Diana Fontinha; et al. "Broad Spectrum Functional Activity of Structurally Related Monoanionic Au(III) Bis(Dithiolene) Complexes". International Journal of Molecular Sciences (2022): https://www.mdpi.com/1422-0067/23/13/7146. 10.3390/ijms23137146 Ana Marques; Ana Belchior; Francisco Silva; Fernanda Marques; Maria Paula Cabral Campello; Teresa Pinheiro; Pedro Santos; et al. "Dose Rate Effects on the Selective Radiosensitization of Prostate Cells by GRPR-Targeted Gold Nanoparticles". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms23095279. 10.3390/ijms23095279 Francisco Silva; Alice D'Onofrio; Carolina Mendes; Catarina Pinto; Ana Marques; M.P.C. Campello; Maria Cristina Oliveira; et al. "Radiolabeled Gold Nanoseeds Decorated with Substance P Peptides: Synthesis, Characterization and In Vitro Evaluation in Glioblastoma Cellular Models". International Journal of Molecular Sciences (2022): https://www.mdpi.com/1422-0067/23/2/617. 10.3390/ijms23020617 Buades, Ana B.; Pereira, Laura C. J.; Vieira, Bruno J. C.; Cerdeira, Ana C.; Waerenborgh, João C.; Pinheiro, Teresa; Matos, António P. A.; et al. "The Mössbauer effect using ⁵⁷Fe-ferrabisdicarbollide ([o-⁵⁷FESAN]^-): a glance into the potential of a low-dose approach for glioblastoma radiotherapy". Inorganic Chemistry Frontiers 9 7 (2022): 1490-1503. http://dx.doi.org/10.1039/d1qi01513c. 10.1039/d1qi01513c Nuez-Martínez, Miquel; Queralt-Martín, María; Muñoz-Juan, Amanda; Aguilella, Vicente M.; Laromaine, Anna; Teixidor, Francesc; Viñas, Clara; et al. "Boron clusters (ferrabisdicarbollides) shaping the future as radiosensitizers for multimodal (chemo/radio/PBFR) therapy of glioblastoma". Journal of Materials Chemistry B 10 47 (2022): 9794-9815. http://dx.doi.org/10.1039/d2tb01818g. Published • 10.1039/d2tb01818g Miquel Nuez-Martinez; Catarina I. G. Pinto; Joana F. Guerreiro; Filipa Mendes; Fernanda Marques; Amanda Muñoz-Juan; Jewel Ann Maria Xavier; et al. "Cobaltabis(dicarbollide) ([o-COSAN]-) as Multifunctional Chemotherapeutics: A Prospective Application in Boron Neutron Capture Therapy (BNCT) for Glioblastoma". Cancers (2021): https://doi.org/10.3390/cancers13246367. 10.3390/cancers13246367 Schlagintweit, Jonas F.; Jakob, Christian H. G.; Wilke, Nicola L.; Ahrweiler, Marie; Frias, Corazon; Frias, Jerico; König, Marcel; et al. "Gold(I) Bis(1,2,3-triazol-5-ylidene) Complexes as Promising Selective Anticancer Compounds". Journal of Medicinal Chemistry (2021): http://dx.doi.org/10.1021/acs.jmedchem.1c01021. 10.1021/acs.jmedchem.1c01021 Joana P. Costa; Sílvia A. Sousa; Catarina Soeiro; Jorge H. Leitão; Adelino M. Galvão; Fernanda Marques; M. Fernanda N. N. Carvalho. "Synthesis and Characterization of Camphorimine Au(I) Complexes with a Remarkably High Antibacterial Activity towards B. contaminans and P. aeruginosa". Antibiotics (2021): https://doi.org/10.3390/antibiotics10101272. 10.3390/antibiotics10101272 Rudbari, Hadi Amiri; Saadati, Arezoo; Aryaeifar, Mahnaz; Correia, Isabel; Marques, Fernanda; Blacque, Olivier; Micale, Nicola. "Cytotoxic oxidovanadium(IV) complexes of tridentate halogen-substituted Schiff bases: First dinuclear V(IV) complexes with O ¿ VIV = O ¿ VIV = O core". Bioorganic & Medicinal Chemistry Letters 49 (2021): 128285. http://dx.doi.org/10.1016/j.bmcl.2021.128285. 10.1016/j.bmcl.2021.128285 Mihaela Cudalbeanu; David Peitinho; Francisco Silva; Rosa Marques; Teresa Pinheiro; Ana C. Ferreira; Fernanda Marques; et al. "Sono-Biosynthesis and Characterization of AuNPs from Danube Delta Nymphaea alba Root Extracts and Their Biological Properties". Nanomaterials 11 6 (2021): 1562-1562. https://doi.org/10.3390/nano11061562. 10.3390/nano11061562 Nunes, Patrique; Correia, Isabel; Cavaco, Isabel; Marques, Fernanda; Pinheiro, Teresa; Avecilla, Fernando; Pessoa, João Costa. "Therapeutic potential of vanadium complexes with 1,10-phenanthroline ligands, quo vadis? Fate of complexes in cell media and cancer cells". Journal of Inorganic Biochemistry 217 (2021): 111350. http://dx.doi.org/10.1016/j.jinorgbio.2020.111350. 10.1016/j.jinorgbio.2020.111350 Ribeiro, Elisabete; Marques, Fernanda; Gano, Lurdes; Correia, João D.G.; Santos, Isabel; Fernandes, Célia. "Docetaxel-loaded block copolymer micelles labeled with 188Re for combined radiochemotherapy". Journal of Drug Delivery Science and Technology 60 (2020): 101898. http://dx.doi.org/10.1016/j.jddst.2020.101898. 10.1016/j.jddst.2020.101898 Marques, Fernanda. "Improved Antiproliferative Activity and Fluorescence of a Dinuclear Gold(I) Bisimidazolylidene Complex via Anthracene-Modification". Chemistry – An Asian Journal (2020): http://dx.doi.org/10.1002/asia.202001104. 10.1002/asia.202001104 Atanu Banerjee; Subhashree P. Dash; Monalisa Mohanty; Gurunath Sahu; Giuseppe Sciortino; Eugenio Garribba; M. Fernanda N. N. Carvalho; et al. "New VIV, VIVO, VVO, and VVO2 Systems: Exploring their Interconversion in Solution, Protein Interactions, and Cytotoxicity". Inorganic Chemistry (2020): https://doi.org/10.1021/acs.inorgchem.0c01837. 10.1021/acs.inorgchem.0c01837 Marques, Fernanda. "Mechanisms underlying the cytotoxic activity of syn/anti-isomers of dinuclear Au(I) NHC complexes.". European journal of medicinal chemistry (2020): https://doi.org/10.1016/j.ejmech.2020.112576. 10.1016/j.ejmech.2020.112576 Marques, Fernanda. "Copper Complexes with 1,10-Phenanthroline Derivatives: Underlying Factors Affecting Their Cytotoxicity". Inorganic Chemistry 59 13 (2020): 9116-9134. http://dx.doi.org/10.1021/acs.inorgchem.0c00925. 10.1021/acs.inorgchem.0c00925 Marques, Fernanda. "Exploring the therapeutic potential of Cu(II)-complexes with ligands derived from pyridoxal". Inorganica Chimica Acta (2020): http://dx.doi.org/10.1016/j.ica.2020.119558. 10.1016/j.ica.2020.119558 Marques, Fernanda. "Antiproliferative Activity of Functionalized Histidine derived Au(I) bis-NHC Complexes for Bioconjugation.". Chemistry, an Asian journal (2020): https://doi.org/10.1002/asia.202000620. 10.1002/asia.202000620 Marques, Fernanda. "Biological properties of a new mixed lanthanide(III) complex incorporating a dypiridinium ylide". Inorganica Chimica Acta (2020): http://dx.doi.org/10.1016/j.ica.2020.119517. 10.1016/j.ica.2020.119517 Busila, Mariana; Tabacaru, Aurel; Mussat, Viorica; Vasile, Bogdan Stefan; Neasu, Ionela Andreea; Pinheiro, Teresa; Roma-Rodrigues, Catarina; et al. "Size-Dependent Biological Activities of Fluorescent Organosilane-Modified Zinc Oxide Nanoparticles". Journal of Biomedical Nanotechnology 16 2 (2020): 137-152. http://dx.doi.org/10.1166/jbn.2020.2882. 10.1166/jbn.2020.2882 Marques, Fernanda. "Dual Imaging Gold Nanoplatforms for Targeted Radiotheranostics". Materials 13 3 (2020): 513-513. http://dx.doi.org/10.3390/ma13030513. 10.3390/ma13030513 Marques, Fernanda. "On the path to gold: Monoanionic Au bisdithiolate complexes with antimicrobial and antitumor activities". Journal of Inorganic Biochemistry (2020): http://dx.doi.org/10.1016/j.jinorgbio.2019.110904. 10.1016/j.jinorgbio.2019.110904 Ricardo G. Teixeira; Fernanda Marques; M. Paula Robalo; Xavier Fontrodona; M. Helena Garcia; Simonetta Geninatti Crich; Clara Viñas; Andreia Valente. "Ruthenium carboranyl complexes with 2,2'-bipyridine derivatives for potential bimodal therapy application". RSC Advances (2020): https://doi.org/10.1039/D0RA01522A. 10.1039/D0RA01522A João Franco Machado; Miguel Machuqueiro; Fernanda Marques; M. Paula Robalo; M. Fátima M. Piedade; M. Helena Garcia; João D. G. Correia; Tânia S. Morais. "Novel "ruthenium cyclopentadienyl" peptide conjugate complexes against human FGFR(+) breast cancer". Dalton Transactions (2020): https://doi.org/10.1039/D0DT00955E. 10.1039/D0DT00955E João Franco Machado; Diogo Sequeira; Fernanda Marques; M. Fátima M. Piedade; Maria J. Villa de Brito; M. Helena Garcia; Alexandra R. Fernandes; Tânia S. Morais. "New copper(i) complexes selective for prostate cancer cells". Dalton Transactions (2020): https://doi.org/10.1039/D0DT02157A. 10.1039/D0DT02157A Marques, Fernanda. "Gold(iii) bis(dithiolene) complexes: from molecular conductors to prospective anticancer, antimicrobial and antiplasmodial agents". Metallomics 12 6 (2020): 974-987. http://dx.doi.org/10.1039/d0mt00064g. 10.1039/d0mt00064g Marques, Fernanda. "Antifungal, Antitumoral and Antioxidant Potential of the Danube Delta Nymphaea alba Extracts". Antibiotics (2019): http://dx.doi.org/10.3390/antibiotics9010007. 10.3390/antibiotics9010007 Marques, Fernanda. "Pt-Fe ferrocenyl compounds with hydroxyquinoline ligands show selective cytotoxicity on highly proliferative cells". Journal of Inorganic Biochemistry (2019): http://dx.doi.org/10.1016/j.jinorgbio.2019.110779. 10.1016/j.jinorgbio.2019.110779 Marques, Fernanda. "Antimicrobial Activity of Silver Camphorimine Complexes against Candida Strains". Antibiotics (2019): http://dx.doi.org/10.3390/antibiotics8030144. 10.3390/antibiotics8030144 Marques, Fernanda. "Exploring the cytotoxic activity of new phenanthroline salicylaldimine Zn(II) complexes". Journal of Inorganic Biochemistry (2019): http://dx.doi.org/10.1016/j.jinorgbio.2019.110727. 10.1016/j.jinorgbio.2019.110727 Marques, Fernanda. "Interaction with Blood Proteins of a Ruthenium(II) Nitrofuryl Semicarbazone Complex: Effect on the Antitumoral Activity". Molecules (2019): http://dx.doi.org/10.3390/molecules24162861. 10.3390/molecules24162861 Marques, Fernanda. "Ruthenium–Cyclopentadienyl Bipyridine–Biotin Based Compounds: Synthesis and Biological Effect". Inorganic Chemistry (2019): http://dx.doi.org/10.1021/acs.inorgchem.9b00735. 10.1021/acs.inorgchem.9b00735 Marques, Fernanda. "Lanthanide complexes with phenanthroline-based ligands: insights into cell death mechanisms obtained by microscopy techniques.". Dalton transactions (Cambridge, England : 2003) (2019): https://doi.org/10.1039/c9dt00640k. 10.1039/c9dt00640k Marques, Fernanda. "Antitumour and Toxicity Evaluation of a Ru(II)-Cyclopentadienyl Complex in a Prostate Cancer Model by Imaging Tools.". Anti-cancer agents in medicinal chemistry (2019): https://doi.org/10.2174/1871520619666190318152726. 10.2174/1871520619666190318152726 Marques, Fernanda. "Polymer "ruthenium-cyclopentadienyl" conjugates - New emerging anti-cancer drugs.". European journal of medicinal chemistry (2019): https://doi.org/10.1016/j.ejmech.2019.02.061. 10.1016/j.ejmech.2019.02.061 Catarina Bravo; M. Paula Robalo; Fernanda Marques; Alexandra R. Fernandes; Diogo A. Sequeira; M. Fátima M. Piedade; M. Helena Garcia; Maria J. Villa de Brito; Tânia S. Morais. "First heterobimetallic Cu(i)–dppf complexes designed for anticancer applications: synthesis, structural characterization and cytotoxicity". New Journal of Chemistry (2019): https://doi.org/10.1039/C9NJ02068C. 10.1039/C9NJ02068C Marques, Fernanda. "Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand.". European journal of medicinal chemistry (2018): https://doi.org/10.1016/j.ejmech.2018.12.022. 10.1016/j.ejmech.2018.12.022 Isabel Fuentes; Tania García-Mendiola; Shinichi Sato; Marcos Pita; Hiroyuki Nakamura; Encarnación Lorenzo; Francesc Teixidor; Fernanda Marques; Clara Viñas. "Metallacarboranes on the Road to Anticancer Therapies: Cellular Uptake, DNA Interaction, and Biological Evaluation of Cobaltabisdicarbollide [COSAN]-". Chemistry - A European Journal 24 65 (2018): 17239-17254. https://doi.org/10.1002/chem.201803178. 10.1002/chem.201803178 Isabel Fuentes; Tania García-Mendiola; Shinichi Sato; Marcos Pita; Hiroyuki Nakamura; Encarnación Lorenzo; Francesc Teixidor; Fernanda Marques; Clara Viñas. "Frontispiece: Metallacarboranes on the Road to Anticancer Therapies: Cellular Uptake, DNA Interaction, and Biological Evaluation of Cobaltabisdicarbollide [COSAN]-". Chemistry - A European Journal 24 65 (2018): https://doi.org/10.1002/chem.201886564. 10.1002/chem.201886564 M. Fernanda N.N. Carvalho; Ana M. Botelho do Rego; Adelino M. Galvão; Rudolf Herrmann; Fernanda Marques. "Search for cytotoxic compounds against ovarian cancer cells: Synthesis, characterization and assessment of the activity of new camphor carboxylate and camphor carboxamide silver complexes". Journal of Inorganic Biochemistry 188 (2018): 88-95. https://doi.org/10.1016/j.jinorgbio.2018.08.011. 10.1016/j.jinorgbio.2018.08.011 Marques, Fernanda. "Photophysical properties and biological evaluation of a Zinc(II)-5-methyl-1H-pyrazole Schiff base complex". Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (2018): http://dx.doi.org/10.1016/j.saa.2018.06.028. 10.1016/j.saa.2018.06.028 Marques, Fernanda. "RuII( p-cymene) Compounds as Effective and Selective Anticancer Candidates with No Toxicity in Vivo.". Inorganic chemistry (2018): https://doi.org/10.1021/acs.inorgchem.8b01270. 10.1021/acs.inorgchem.8b01270 Marques, Fernanda. "Synthesis, characterization and antitumor activity of two new dipyridinium ylide based lanthanide(III) complexes". Inorganica Chimica Acta (2018): http://dx.doi.org/10.1016/j.ica.2018.05.003. 10.1016/j.ica.2018.05.003 Marques, Fernanda. "Methyl-cyclopentadienyl Ruthenium Compounds with 2,2'-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential". Inorganic Chemistry (2018): http://dx.doi.org/10.1021/acs.inorgchem.8b00358. 10.1021/acs.inorgchem.8b00358 Tânia S. Morais; Yann Jousseaume; M. Fátima M. Piedade; Catarina Roma-Rodrigues; Alexandra R. Fernandes; Fernanda Marques; Maria J. Villa de Brito; M. Helena Garcia. "Important cytotoxic and cytostatic effects of new copper(i)–phosphane compounds with N,N, N,O and N,S bidentate ligands". Dalton Transactions 47 23 (2018): 7819-7829. https://doi.org/10.1039/C8DT01653D. 10.1039/C8DT01653D Marques, Fernanda. "Heteroleptic oxidovanadium(IV) complexes of 2-hydroxynaphtylaldimine and polypyridyl ligands against Trypanosoma cruzi and prostate cancer cells". Journal Inorganic Biochemistry (2017): Marques, Fernanda. "New Cu(II) complexes with pyrazolyl derived Schiff base ligands: Synthesis and biological evaluation". Journal Inorganic Biochemistry (2017): Marques, Fernanda. "Interaction of [VIV O(acac)2 ] with Human Serum Transferrin and Albumin". Chem Asian J (2017): Marques, Fernanda. "A Multifunctional Radiotheranostic Agent for Dual Targeting of Breast Cancer Cells". ChemMedChem (2017): Marques, Fernanda. "Dinuclear RuII(bipy)2 Derivatives: Structural, Biological, and in Vivo Zebrafish Toxicity Evaluation". Inorganic Chemistry (2017): Marques, Fernanda. "New copper(I) and heteronuclear copper(I)-ruthenium(II) complexes: Synthesis, structural characterization and cytotoxicity". J Inorg Biochem (2017): Marques, Fernanda. "Ultrastructural features of cells following incubation with metal complexes using phenanthroline-based ligands: The influence of the metal center". Ultrastructural Pathology (2017): Marques, Fernanda. "Synthesis and Biological Evaluation of Novel 2-Aryl Benzimidazoles as Chemotherapeutic Agents". J Heterocyclic Chem (2017): http://onlinelibrary.wiley.com/doi/10.1002/jhet.2575/epdf. Marques, Fernanda. "BODIPY-17a-ethynylestradiol conjugates: Synthesis, fluorescence properties and receptor binding affinities". Bioorg Med Chem Lett (2017): http://www.sciencedirect.com/science/article/pii/S0960894X16313269. Marques, Fernanda. "Evaluation of cellular uptake, cytotoxicity and cellular ultrastructural effects of heteroleptic oxidovanadium(IV) complexes of salicylaldimines and polypyridyl ligands". J Inorg Biochem (2017): http://www.sciencedirect.com/science/article/pii/S0162013416303804. Marques, Fernanda. "In vitro and in vivo trackable titanocene-based complexes using optical imaging or SPECT". Dalton Trans (2017): Marques, Fernanda. "In Vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model". Anticancer Agents Med Chem (2017): http://www.eurekaselect.com/145730/article. Océane Florès; Audrey Trommenschlager; Souheila Amor; Fernanda Marques; Francisco Silva; Lurdes Gano; Franck Denat; et al. "In vitro and in vivo trackable titanocene-based complexes using optical imaging or SPECT". Dalton Transactions 46 42 (2017): 14548-14555. https://doi.org/10.1039/C7DT01981E. 10.1039/C7DT01981E Marques, Fernanda. "Unraveling the mode of action of new promising polymer-ruthenium conjugates". Ultrastruct Pathol (2017): http://www.tandfonline.com/doi/abs/10.1080/01913123.2016.1272669?journalCode=iusp20. Marques, Fernanda. "Studies on the mechanism of action of antitumor bis(aminophenolate) ruthenium(III) complexes". J Inorg Biochem (2017): http://www.sciencedirect.com/science/article/pii/S0162013416304998. Marques, Fernanda. "Coordination ability and biological activity of a naringenin thiosemicarbazone". (2016): http://www.sciencedirect.com/science/article/pii/S016201341630277X. Marques, Fernanda. "Tracking antitumor metallodrugs: promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds". Future Med Chem (2016): Marques, Fernanda. "Synthesis of Ag(I) camphor sulphonylimine complexes and assessment of their cytotoxic properties against cisplatin-resistant A2780cisR and A2780 cell lines". J Inorg Biochem (2016): http://www.sciencedirect.com/science/article/pii/S0162013416303749. Marques, Fernanda. "Radiolabeled block copolymer micelles for image-guided drug delivery". Int J Pharm (2016): http://www.sciencedirect.com/science/article/pii/S0378517316310559. Marques, Fernanda. "Novel (188)Re multi-functional bone-seeking compounds: Synthesis, biological and radiotoxic effects in metastatic breast cancer cells". Nucl Med Biol (2016): Marques, Fernanda. "Heteroleptic mononuclear compounds of ruthenium(II): synthesis, structural analyses, in vitro antitumor activity and in vivo toxicity on zebrafish embryos". Dalton Trans (2016): http://pubs.rsc.org/en/content/articlepdf/2016/dt/c6dt03591d. Marques, Fernanda. "Vanadium(IV) and copper(II) complexes of salicylaldimines and aromatic heterocycles: cytotoxicity, DNA binding and DNA cleavage properties". J Inorg Biochem (2015): Marques, Fernanda. "A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites". J Coordination Chemistry (2015): http://www.tandfonline.com/doi/abs/10.1080/00958972.2015.1062480. Marques, Fernanda. "The key role of coligands in novel ruthenium(II)-cyclopentadienyl bipyridine derivatives: Ranging from non-cytotoxic to highly cytotoxic compounds". J Inorg Biochem (2015): http://www.sciencedirect.com/science/article/pii/S0162013415300209. Morais, T.S.; Santos, F.C.; Jorge, T.F.; Côrte-Real, L.; Madeira, P.J.A.; Marques, F.; Robalo, M.P.; et al. "New water-soluble ruthenium(II) cytotoxic complex: Biological activity and cellular distribution". Journal of Inorganic Biochemistry 130 1 (2014): 1-14. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885498325&partnerID=MN8TOARS. 10.1016/j.jinorgbio.2013.09.013 Marques, Fernanda. "Synthesis, characterization and biological evaluation of carboranylmethylbenzo[b]acridones as novel agents for boron neutron capture therapy". Org Biomol Chem (2014): http://pubs.rsc.org/en/content/articlepdf/2014/ob/c4ob00644e. Marques, Fernanda. "Anticancer activity of structurally related ruthenium(II) cyclopentadienyl complexes". J Biol Inorg Chem (2014): Marques, Fernanda. "Hydroxyquinoline derived vanadium(IV and V) and copper(II) complexes as potential anti-tuberculosis and anti-tumor agents". J Inorg Biochem (2014): http://www.sciencedirect.com/science/article/pii/S0162013414002165. Fernandes, C.; Monteiro, S.; Mendes, P.; Gano, L.; Marques, F.; Casimiro, S.; Costa, L.; Correia, J.D.G.; Santos, I.. "Biological assessment of novel bisphosphonate-containing 99mTc/Re-organometallic complexes". Journal of Organometallic Chemistry (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84886959842&partnerID=MN8TOARS. 10.1016/j.jorganchem.2013.10.038 Matos, C.P.; Valente, A.; Marques, F.; Adão, P.; Paula Robalo, M.; De Almeida, R.F.M.; Pessoa, J.C.; et al. "New polydentate Ru(III)-Salan complexes: Synthesis, characterization, anti-tumour activity and interaction with human serum proteins". Inorganica Chimica Acta 394 (2013): 616-626. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868218698&partnerID=MN8TOARS. 10.1016/j.ica.2012.09.026 Marques, S.M.; Abate, C.C.; Chaves, S.; Marques, F.; Santos, I.; Nuti, E.; Rossello, A.; Santos, M.A.. "New bifunctional metalloproteinase inhibitors: An integrated approach towards biological improvements and cancer therapy". Journal of Inorganic Biochemistry 127 (2013): 188-202. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884417690&partnerID=MN8TOARS. 10.1016/j.jinorgbio.2013.03.003 Morais, T.S.; Santos, F.; Côrte-Real, L.; Marques, F.; Robalo, M.P.; Madeira, P.J.A.; Garcia, M.H.. "Biological activity and cellular uptake of [Ru(¿5-C 5H5)(PPh3)(Me2bpy)][CF 3SO3] complex". Journal of Inorganic Biochemistry 122 (2013): 8-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873704110&partnerID=MN8TOARS. 10.1016/j.jinorgbio.2013.01.011 Demoro, B.; De Almeida, R.F.M.; Marques, F.; Matos, C.P.; Otero, L.; Costa Pessoa, J.; Santos, I.; et al. "Screening organometallic binuclear thiosemicarbazone ruthenium complexes as potential anti-tumour agents: Cytotoxic activity and human serum albumin binding mechanism". Dalton Transactions 42 19 (2013): 7131-7146. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876935350&partnerID=MN8TOARS. 10.1039/c3dt00028a Gonçalves, A.C.; Morais, T.S.; Robalo, M.P.; Marques, F.; Avecilla, F.; Matos, C.P.; Santos, I.; Tomaz, A.I.; Garcia, M.H.. "Important cytotoxicity of novel iron(II) cyclopentadienyl complexes with imidazole based ligands". Journal of Inorganic Biochemistry 129 (2013): 1-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882795489&partnerID=MN8TOARS. 10.1016/j.jinorgbio.2013.07.033 Valente, A.; Garcia, M.H.; Marques, F.; Miao, Y.; Rousseau, C.; Zinck, P.. "First polymer "ruthenium-cyclopentadienyl" complex as potential anticancer agent". Journal of Inorganic Biochemistry 127 (2013): 79-81. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884576725&partnerID=MN8TOARS. 10.1016/j.jinorgbio.2013.07.002 Côrte-Real, L.; Matos, A.P.; Alho, I.; Morais, T.S.; Tomaz, A.I.; Garcia, M.H.; Santos, I.; Bicho, M.P.; Marques, F.. "Cellular uptake mechanisms of an antitumor ruthenium compound: The endosomal/lysosomal system as a target for anticancer metal-based drugs". Microscopy and Microanalysis 19 5 (2013): 1122-1130. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884579362&partnerID=MN8TOARS. 10.1017/S143192761300175X Oliveira, M.C.; Neto, C.; Gano, L.; Marques, F.; Santos, I.; Thiemann, T.; Santos, A.C.; Botelho, F.; Oliveira, C.F.. "Estrogen receptor ligands for targeting breast tumours: A brief outlook on radioiodination strategies". Current Radiopharmaceuticals 5 2 (2012): 124-141. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857132356&partnerID=MN8TOARS. 10.2174/1874471011205020124 Neto, C.; Oliveira, M.C.; Gano, L.; Marques, F.; Thiemann, T.; Santos, I.. "Novel estradiol based metal complexes of Tc-99m". Journal of Inorganic Biochemistry 111 (2012): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860528917&partnerID=MN8TOARS. 10.1016/j.jinorgbio.2012.03.001 Neto, C.; Oliveira, M.C.; Gano, L.; Marques, F.; Yasuda, T.; Thiemann, T.; Kniess, T.; Santos, I.. "Novel 7a-alkoxy-17a-(4'-halophenylethynyl)estradiols as potential SPECT/PET imaging agents for estrogen receptor expressing tumours: Synthesis and binding affinity evaluation". Steroids 77 11 (2012): 1123-1132. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865491838&partnerID=MN8TOARS. 10.1016/j.steroids.2012.05.004 Morais, T.S.; Silva, T.J.L.; Marques, F.; Robalo, M.P.; Avecilla, F.; Madeira, P.J.A.; Mendes, P.J.G.; Santos, I.; Garcia, M.H.. "Synthesis of organometallic ruthenium(II) complexes with strong activity against several human cancer cell lines". Journal of Inorganic Biochemistry 114 (2012): 65-74. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861986235&partnerID=MN8TOARS. 10.1016/j.jinorgbio.2012.04.014 Gama, S.; Mendes, F.; Esteves, T.; Marques, F.; Matos, A.; Rino, J.; Coimbra, J.; et al. "Synthesis and Biological Studies of Pyrazolyl-Diamine PtII Complexes Containing Polyaromatic DNA-Binding Groups". ChemBioChem 13 16 (2012): 2352-2362. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868093608&partnerID=MN8TOARS. 10.1002/cbic.201200472 Tomaz, A.I.; Jakusch, T.; Morais, T.S.; Marques, F.; De Almeida, R.F.M.; Mendes, F.; Enyedy, É.A.; et al. "[RuII(¿5-C5H5 (bipy)(PPh3)]+, a promising large spectrum antitumor agent: Cytotoxic activity and interaction with human serum albumin". Journal of Inorganic Biochemistry 117 (2012): 261-269. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869080345&partnerID=MN8TOARS. 10.1016/j.jinorgbio.2012.06.016 Gama, S.; Santos, I.; Mendes, F.; Marques, F.; Santos, I.C.; Carvalho, M.F.; Correia, I.; Pessoa, J.C.; Paulo, A.. "Copper(II) complexes with tridentate pyrazole-based ligands: Synthesis, characterization, DNA cleavage activity and cytotoxicity". Journal of Inorganic Biochemistry 105 5 (2011): 637-644. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953066808&partnerID=MN8TOARS. 10.1016/j.jinorgbio.2011.01.013 Francisco, C.; Gama, S.; Mendes, F.; Marques, F.; Cordeiro Dos Santos, I.; Paulo, A.; Santos, I.; et al. "Pt(ii) complexes with bidentate and tridentate pyrazolyl-containing chelators: Synthesis, structural characterization and biological studies". Dalton Transactions 40 21 (2011): 5781-5792. http://www.scopus.com/inward/record.url?eid=2-s2.0-79957530790&partnerID=MN8TOARS. 10.1039/c0dt01785j Esteves, T.; Marques, F.; Paulo, A.; Rino, J.; Nanda, P.; Smith, C.J.; Santos, I.. "Nuclear targeting with cell-specific multifunctional tricarbonyl M(I) (M is Re, 99mTc) complexes: Synthesis, characterization, and cell studies". Journal of Biological Inorganic Chemistry 16 8 (2011): 1141-1153. http://www.scopus.com/inward/record.url?eid=2-s2.0-84655169705&partnerID=MN8TOARS. 10.1007/s00775-011-0803-x Gambino, D.; Fernández, M.; Santos, D.; Etcheverría, G.A.; Piro, O.E.; Pavan, F.R.; Leite, C.Q.F.; Tomaz, I.; Marques, F.. "Searching for gallium bioactive compounds: Gallium(III) complexes of tridentate salicylaldehyde semicarbazone derivatives". Polyhedron 30 7 (2011): 1360-1366. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953861653&partnerID=MN8TOARS. 10.1016/j.poly.2011.02.037 Neto, Carina; Oliveira, Maria Cristina; Gano, Lurdes; Marques, Fernanda; Santos, Isabel; Thiemann, T.. "Novel estradiol based metal complexes of Tc-99m for breast cancer imaging". Nuclear Medicine and Biology 37 6 (2010): 699-700. 10.1016/j.nucmedbio.2010.04.065 Lacerda, S.; Marques, F.; Campello, P.; Gano, L.; Kubícek, V.; Hermann, P.; Santos, I.. "Chemical, radiochemical and biological studies of Sm and Ho complexes of H4dota analogues containing one methylphosphonic/phosphinic acid pendant arm". Journal of Labelled Compounds and Radiopharmaceuticals 53 1 (2010): 36-43. http://www.scopus.com/inward/record.url?eid=2-s2.0-76249129110&partnerID=MN8TOARS. 10.1002/jlcr.1697 Silva, F.; Marques, F.; Santos, I.C.; Paulo, A.; Rodrigues, A.S.; Rueff, J.; Santos, I.. "Synthesis, characterization and cytotoxic activity of gallium(III) complexes anchored by tridentate pyrazole-based ligands". Journal of Inorganic Biochemistry 104 5 (2010): 523-532. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950691262&partnerID=MN8TOARS. 10.1016/j.jinorgbio.2010.01.003 Esteves, T.; Xavier, C.; Gama, S.; Mendes, F.; Raposinho, P.D.; Marques, F.; Paulo, A.; et al. "Tricarbonyl M(I) (M = Re, 99mTc) complexes bearing acridine fluorophores: Synthesis, characterization, DNA interaction studies and nuclear targeting". Organic and Biomolecular Chemistry 8 18 (2010): 4104-4116. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955948795&partnerID=MN8TOARS. 10.1039/c0ob00073f Lima, L.M.P.; Delgado, R.; Marques, F.; Gano, L.; Santos, I.. "TETA analogue containing one methylenephosphonate pendant arm: Lanthanide complexes and biological evaluation of its 153Sm and 166Ho complexes". European Journal of Medicinal Chemistry 45 12 (2010): 5621-5627. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649318835&partnerID=MN8TOARS. 10.1016/j.ejmech.2010.09.013 Neto, C.; Oliveira, M.C.; Gano, L.; Marques, F.; Santos, I.; Morais, G.; Yasuda, T.; et al. "Evaluation of novel radioiodinated C7-substituted ¿6,7-estradiol derivatives for molecular recognition of er-positive breast tumours". Current Radiopharmaceuticals 2 2 (2009): 83-91. http://www.scopus.com/inward/record.url?eid=2-s2.0-68149090478&partnerID=MN8TOARS. 10.2174/1874471010902020083 Neto, C.; Oliveira, M.C.; Gano, L.; Marques, F.; Santos, I.; Morais, G.R.; Yasuda, T.; et al. "Radioiodinated ligands for the estrogen receptor: Effect of different 7-cyanoalkyl chains on the binding affinity of novel iodovinyl-6-dehydroestradiols". Applied Radiation and Isotopes 67 2 (2009): 301-307. http://www.scopus.com/inward/record.url?eid=2-s2.0-58049153116&partnerID=MN8TOARS. 10.1016/j.apradiso.2008.10.005 Marques, F.; Gano, L.; Batista, M.K.S.; Gomes, C.A.R.; Gomes, P.; Santos, I.. "Radiochemical and biological evaluation of novel 153Sm/ 166Ho-amino acid-chitosan complexes". Journal of Labelled Compounds and Radiopharmaceuticals 52 3 (2009): 79-83. http://www.scopus.com/inward/record.url?eid=2-s2.0-62849096351&partnerID=MN8TOARS. 10.1002/jlcr.1571 Lacerda, S.; Campello, M.P.; Marques, F.; Gano, L.; Kubíek, V.; Fousková, P.; Tóth, E.; Santos, I.. "A novel tetraazamacrocycle bearing a thiol pendant arm for labeling biomolecules with radiolanthanides". Dalton Transactions 23 (2009): 4509-4518. http://www.scopus.com/inward/record.url?eid=2-s2.0-67749147121&partnerID=MN8TOARS. 10.1039/b820375j Vitor, Rute F.; Esteves, Teresa; Marques, Fernanda; Raposinho, Paula; Paulo, Antonio; Rodrigues, Sebastiao; Rueff, Jose; et al. "Tc-99m-Tricarbonyl Complexes Functionalized with Anthracenyl Fragments: Synthesis, Characterization, and Evaluation of Their Radiotoxic Effects in Murine Melanoma Cells". Cancer Biotherapy and Radiopharmaceuticals 24 5 (2009): 551-563. 10.1089/cbr.2009.0647 De Almeida, E.A.F.; Alho, I.; Marques, F.; Thiran, C.; Bicho, M.P.; Prata, M.. "Haemoglobin and erythropoietin levels in polycystic kidney disease". Nephrology Dialysis Transplantation 23 1 (2008): 412-413. http://www.scopus.com/inward/record.url?eid=2-s2.0-44449142934&partnerID=MN8TOARS. 10.1093/ndt/gfm717 Vitor, R.F.; Correia, I.; Videira, M.; Marques, F.; Paulo, A.; Costa Pessoa, J.; Viola, G.; Martins, G.G.; Santos, I.. "Pyrazolyl-diamine ligands that bear anthracenyl moieties and their rhenium(I) tricarbonyl complexes: Synthesis, characterisation and DNA-binding properties". ChemBioChem 9 1 (2008): 131-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-38149057217&partnerID=MN8TOARS. 10.1002/cbic.200700433 Försterová, M.; Jandurová, Z.; Marques, F.; Gano, L.; Lubal, P.; Vanek, J.; Hermann, P.; Santos, I.. "Chemical and biological evaluation of 153Sm and 166Ho complexes of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylphosphonic acid monoethylester) (H4dotpOEt)". Journal of Inorganic Biochemistry 102 7 (2008): 1531-1540. http://www.scopus.com/inward/record.url?eid=2-s2.0-44649181534&partnerID=MN8TOARS. 10.1016/j.jinorgbio.2008.02.002 Gano, L.; Marques, F.; Campbello, M.P.; Balbina, M.; Lacerda, S.; Santos, I.. "Radiolanthanide complexes with tetraazamacrocycles bearing methylphosphonate pendant arms as bone seeking agents". Quarterly Journal of Nuclear Medicine and Molecular Imaging 51 1 (2007): 6-15. http://www.scopus.com/inward/record.url?eid=2-s2.0-34249731389&partnerID=MN8TOARS. Campello, M.P.; Marques, F.; Gano, L.; Lacerda, S.; Santos, I.. "Radiochemical and biological behaviour of 153Sm and 166Ho complexes anchored by a novel bis(methylphosphonate) tetraazamacrocycle". Radiochimica Acta 95 6 (2007): 329-334. http://www.scopus.com/inward/record.url?eid=2-s2.0-34250782134&partnerID=MN8TOARS. 10.1524/ract.2007.95.6.329 Marques, F.; Gano, L.; Campello, M.P.; Lacerda, S.; Santos, I.. "Biological evaluation of 153Sm and 166Ho complexes with tetraazamacrocycles containing methylcarboxylate and/or methylphosphonate pendant arms". Radiochimica Acta 95 6 (2007): 335-341. http://www.scopus.com/inward/record.url?eid=2-s2.0-34250729721&partnerID=MN8TOARS. 10.1524/ract.2007.95.6.335 Marques, F.; Gano, L.; Paula Campello, M.; Lacerda, S.; Santos, I.; Lima, L.M.P.; Costa, J.; Antunes, P.; Delgado, R.. "13- and 14-membered macrocyclic ligands containing methylcarboxylate or methylphosphonate pendant arms: Chemical and biological evaluation of their 153Sm and 166Ho complexes as potential agents for therapy or bone pain palliation". Journal of Inorganic Biochemistry 100 2 (2006): 270-280. http://www.scopus.com/inward/record.url?eid=2-s2.0-30544449145&partnerID=MN8TOARS. 10.1016/j.jinorgbio.2005.11.011 Marques, F.; Paulo, A.; Campello, M.P.; Lacerda, S.; Vitor, R.F.; Gano, L.; Delgado, R.; Santos, I.. "Radiopharmaceuticals for targeted radiotherapy". Radiation Protection Dosimetry 116 1-4 (2005): 601-604. http://www.scopus.com/inward/record.url?eid=2-s2.0-31544473459&partnerID=MN8TOARS. 10.1093/rpd/nci251 Marques, F.; Guerra, K.P.; Gano, L.; Costa, J.; Campello, M.P.; Lima, L.M.P.; Delgado, R.; Santos, I.. "153Sm and 166Ho complexes with tetraaza macrocycles containing pyridine and methylcarboxylate or methylphosphonate pendant arms". Journal of Biological Inorganic Chemistry 9 7 (2004): 859-872. http://www.scopus.com/inward/record.url?eid=2-s2.0-8644263006&partnerID=MN8TOARS. 10.1007/s00775-004-0587-3 Marques, F.; Crespo, M.E.; Silva, Z.I.; Bicho, M.. "Insulin and high glucose modulation of phosphatase and reductase enzymes in the human erythrocytes: A comparative analysis in normal and diabetic states". Diabetes Research and Clinical Practice 47 3 (2000): 191-198. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033964923&partnerID=MN8TOARS. 10.1016/S0168-8227(99)00128-X Marques, F.; Crespo, M.E.; Silva, Z.I.; Bicho, M.. "Redox modulation of reductase and phosphatase activities in human erythrocytes". Protoplasma 206 1-3 (1998): 168-173. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032443022&partnerID=MN8TOARS. Marques, F.; Bicho, M.P.. "Activation of a NADH dehydrogenase in the human erythrocyte by beta-adrenergic agonists: Possible involvement of a G protein in enzyme activation". Biological Signals 6 2 (1997): 52-61. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030837384&partnerID=MN8TOARS. Marques, F.; Duarte, R.O.; Moura, J.J.G.; Bicho, M.P.. "Conversion of adrenaline to indolic derivatives by the human erythrocyte plasma membrane". Biological Signals 5 5 (1996): 275-282. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029823729&partnerID=MN8TOARS. Marques, F; Crespo, ME; Pantaleao, O; Bicho, M. "Insulin activation of NADH ferricyanide reductase in human erythrocytes is mediated by the insulin receptor tyrosine kinase: A comparative study in normal and diabetic states". Redox Report 2 6 (1996): 373-378. NEVES, M; REIS, MF; WAERENBORGH, F; MARTINHO, E; PATRICIO, L. "HO-166 - A POTENTIAL LANTHANIDE ELEMENT IN RADIOTHERAPY". Inorganica Chimica Acta 140 1-2 (1987): 359-360. 10.1016/S0020-1693(00)81123-8 NEVES, M; WAERENBORGH, F; PATRICIO, L. "PD-109 AND HO-166 POTENTIAL RADIONUCLIDES FOR SYNOVIOTHERAPY RADIATION ABSORBED DOSE CALCULATIONS". Applied Radiation and Isotopes 38 9 (1987): 745-749. Neves, M; Waerenborgh, F; Patricio, L. "Palladium-109 and holmium-166 potential radionuclides for synoviotherapy--radiation absorbed dose calculations.". International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 38 9 (1987): 745-9. 10.1016/0883-2889(87)90256-5 SANTOS, I; WAERENBORGH, F; PATRICIO, L. "COUPLING OF A SHEEP ANTI-T3 IGG TO A SOLID-PHASE FOR A TRIIODOTHYRONINE RADIOIMMUNOASSAY". Journal of Radioanalytical and Nuclear Chemistry-Articles 102 1 (1986): 143-148. 10.1007/BF02037955 NEVES, MA; MARTINHO, E; FREITAS, MC; WAERENBORGH, F; MATOS, AP. "PD-109 - A NEW RADIOCOLLOID". International Journal of Applied Radiation and Isotopes 35 6 (1984): 546-547. 10.1016/0020-708X(84)90180-7
Thesis / Dissertation	Marques, Fernanda. "Contribuição para o estudo de fenómenos redox na membrana citoplasmática modificados pelas catecolaminas". PhD, Universidade de Lisboa Faculdade de Ciências, 1993.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2018/12	Carboranyl-containing acridone derivatives with dual application in boron neutron capture therapy and photodynamic therapy: biological studies in human glioblastoma cells	PBSi International Conference on phosphorus, Boron and Silicon (Barcelona, Spain)
2018/12	Metallocarboranes with dual application in boron neutron capture therapy and radiation therapy: biological studies in human glioblastoma cells	PBSi International Conference on Phosphorus, Boron and Silicon (Barcelona, Spain)
2015/09	Bis(phosphonate)-containing 99m-Tc/188-Re organometallic complexes for theranostic applications	COST TD1004 Final Annual Meeting Serbian Academy of Sciences and Arts (Belgrade, Serbia)
2014	Ruthenium-based anticancer compounds: insights into their uptake mechanisms and cellular targets	4th World Congress on Cancer Science & Therapy, Chicago, USA (Chicago, United States)
2013	Novel pathways for anticancer therapy: the role of golgi network in the mechanism of cell death of organometallic complexes	MFS2013-Microscopy at the Frontiers of Science (Tarragona, Spain)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2020/06 - Current	Steroid-BODIPY Theranostics: Receptor-mediated cell uptake and applications in cancer diagnostic and therapy Co-supervisor	Universidade Nova de Lisboa, Portugal
2020 - Current	Evaluation of the Radiosensitizing Capabilities of Target-Specific Gold Nanoparticles (AuNPs) in the Radiotherapy of Glioblastoma Supervisor	Science in Energy and Nuclear Engineering (Master) Politecnico di Torino, Italy
2016 - 2016	Síntese de novos complexos de ruténio para tratamento dos adenomas da hipófise Co-supervisor	Química (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2012 - 2012	Complexos de Ruténio como potenciais agentes terapêuticos: estudos dos mecanismos de captação celular e modulação de enzimas metabólicos Supervisor of Leonor de Sá Nogueira Côrte-Real	Química Inorgânica Biomédica: Aplicações em Diagnóstico e Terapia (Master) Universidade de Lisboa Faculdade de Ciências, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2000 - 2020	Synthesis and evaluation of C-7 substituted estra-1,3,5(10),6 tetraenes as diagnostica for estrogen positive human breast cancer Meeting	78th Annual Spring Meeting of the Chemical Society of Japan Koeki Shadan Hojin Nihon Seikagakukai, Japan
2019/08 - 2019/08	Pt-Fe heterobimetallic ferrocenyl derivatives show cytotoxicity on highly proliferative cells Congress	19Th International Congress on Biological Inorganic Chemistry
2019/06/04 - 2019/06/06	Modification of ZnO nanoparticles with silanes enables their application as anticancer agents Congress	4th International Congress of CiiEM Centro de Investigação Interdisciplinar Egas Moniz, Portugal
2019/06 - 2019/06	Gold(III) bisdithiolate complexes: molecular conductors that also exhibit anticancer and antimicrobial activities Congress	4th International Congress of CiiEM Centro de Investigação Interdisciplinar Egas Moniz, Portugal
2018/06 - 2018/06	Cellular ultrastructural studies and biological effects of copper complexes of phenanthroline derivatives Congress	3th International Congress of CiiEM Centro de Investigação Interdisciplinar Egas Moniz, Portugal
2016/04 - 2016/04	Bodipy-estradiol conjugates as multi-modality tumor imaging agents Congress	18th European Symposium on Radiopharmacy and Radiopharmaceuticals
2015/12 - 2015/12	Heteroleptic oxidovanadium(IV) complexes of salicylaldimines and polypyridyl ligands: cytotoxicity and mechanism of action Congress	1st International Symposium on Clinical and Experimental Mettalodrugs in Medicine: Cancer chemotherapy
2015/11/02 - 2015/11/04	On the mode of action of new promising anticancer agents: multifunctional polymer-ruthenium conjugates Conference	4th International Conference on Medicinal Chemistry & Computor Aided Drug Design
2015/11 - 2015/11	Microscopic analysis of the antitumor effects of ruthenium complexes in a prostate cancer model Congress	1st International Congress of CiiEM Centro de Investigação Interdisciplinar Egas Moniz, Portugal
2015/08 - 2015/08	Multifunctional polymer-ruthenium cyclopentadienyl complexes: applications as anticancer agents for photodynamic therapy Congress	16th Congress of the European Society for Photobiology
2015/07 - 2015/07	Synthesis and biological evaluation of new carboranylmethyl-benzo(b)acridones as novel agents for boron neutron capture therapy Congress	Molecular and Supramolecular Carriers for Imaging and Therapy
2015/07 - 2015/07	Block copolymer micelles for cancer therapy Conference	Trace and Treat Conference on Molecular and Supramolecular Carriers for Imaging and Therapy Technische Universiteit Delft, Netherlands
2015/06 - 2015/06	Zn(II) salGly)(phenanthroline) complexes-synthesis, characterization and cytotoxicty Congress	International Symposia on Metal Complexes -ISMEC
2014 - 2014	Block copolymer micelles for cancer therapy Congress	XVIII Congress of the Portuguese Biochemical Society
2013 - 2013	111-In-DOTAGA-estradiol based complexes with binding affinity for the estrogen receptor Meeting	1st Symposium on Medicinal Chemistry
2013 - 2013	Interaction with proteins and antitumoral activity of a ruthenium semicarbazone complex Meeting	12th International Symposium on metal ions in biology and medicine
2013 - 2013	Cyclopentadienyl ruthenium (macro)metallodrugs: large spectrum antitumor agents Congress	Drug Discovery & therapy World Congress
2013 - 2013	Searching for gallium(III) bioactive compounds: a new gallium(III) complexes as prospective anti-tumoral and anti-trypanosome cruzi compound Symposium	12th International Symposium on Metal Ions in Biology and Medicine
2013 - 2013	Cyclopentadienyl ruthenium (macro)metallodrugs: large spectrum antitumor agents Congress	Drug Discovery & Therapy World Congress
2012 - 2012	Organoruthenium binuclear thiosemicarbazone complexes as potential antitumor agents Meeting	international Symposium on Metal Complexes-ISMEC
2012 - 2012	New polydentate Ru(III)-salan complexes: synthesis, characterization, antitumor activity and interaction with human serum proteins Symposium	ISMEC-2012 International Symposium on Metal Complexes
2012 - 2012	Promising organometallic ruthenium metallodrugs: (RuII(eta(5)-Cp)(bpy)(PPh3)+, a large spectrum antitumor agent Meeting	3º Encontro Nacional de Química Terapêutica da Sociedade Portuguesa de Química Sociedade Portuguesa de Química, Portugal
2012 - 2012	Intracellular distribution of antitumor Ru(II) compounds: the lysosome and the lysosomal enzymes as targets for anticancer metal-based drugs Congress	XLVI Congress of the Portuguese Society for Microscopy (SPMicros)
2012 - 2012	New polydentate Ru(III)-salan complexes : synthesis, characterization, antitumor activity and interaction with human serum proteins Symposium	International Symposium on Metal Complexes (ISMEC 2012)
2011 - 2011	New ruthenium(II) polypyridyl complexes as potential antitumor agents: synthesis , characterization and antiproliferative activity Conference	4th European Conference on Chemistry for Life Sciences (4ECCLS)
2011 - 2011	New Ruthenium tridentate amino-phenolate complexes: characterization and study of their biological activity Meeting	11th International Symposium on Applied Bioinorganic Chemistry (ISABC 11)
2011 - 2011	A promising large spectrum antitumor ruthenium agent: interaction with serum proteins and mechanisms of cell death Conference	4th European Conference on Chemistry for Life Sciences (4ECCLS)
2011 - 2011	Synthesis and cytotoxicity of new ruthenium(II) complexes for antitumor application Meeting	XXII Encontro Nacional da Sociedade Portuguesa de Química Sociedade Portuguesa de Química, Portugal
2010/09 - 2010/09	Novel estradiol based metal complexes of TC-99m for breast cancer Meeting	International Symposium on Technetium and Other Radiometals in Chemistry and Medicine
2010 - 2010	New Pt(II) complexes with bidentate and tridentate pyrazolyl-containing chelators: synthesis, structural studies and in vitro antitumor activity Conference	EUROBIC 10
2010 - 2010	Trifunctional tricarbony complexes for cell-specific and nuclear targeting Conference	TERACHEM 2010
2010 - 2010	New (99m-Tc(CO)3)+-labelled bombesin conjugates bearing an acridine orange moiety for diagnosis and/or therapy of cancer Meeting	EPI XII-Iberian Peptide Meeting
2010 - 2010	New (99mTc(CO)3+ labeled bombesin conjugates bearing an acridine orange moiety for diagnosis and/or therapy of cancer Meeting	EPI XII Iberian Peptide Meeting
2009/09 - 2009/09	Estradiol based metal complexes for breast cancer diagnosis Meeting	10th International Symposium on Applied Bioinorganic Chemistry
2009 - 2009	Platinum(II) complexes with pyrazolyl-diamine chelators bearing DNA-binding groups Meeting	COST ACTION D39 - Metallo-Drug Design and Action
2009 - 2009	Copper(II) complexes fo pyrazole-salen ligands: synthesis, characterization, DNA-binding properties and cytotoxicity Meeting	FIGIPAS 10th International Meeting in Inorganic Chemistry
2009 - 2009	Estradiol based metal complexes for breast cancer diagnosis Meeting	10th International Symposium on Applied Bioinorganic Chemistry
2008 - 2008	Tricarbonyl complexes containing acridine fluorophores for multimodal imaging Congress	World Molecular Imaging Congress
2008 - 2008	Novel radioiodinated estradiols as potential imaging agents for estrogen breast tumors Congress	World Molecular Imaging Congress
2008 - 2008	Novel estra-1,3,5(10),6(7)-tetraen-3,17(beta)diols as potential radioligands for the estrogen receptor Conference	10th Eurasia Conference of Chemical Sciences (EuAs C2S-10)
2007 - 2007	Synthesis, structural characterization and biological studies of homoleptic gallium(III) complexes with novel tridentate (N,N´O) chelators Congress	Congresso de Química Inorgânica da SPQ Sociedade Portuguesa de Química, Portugal
2007 - 2007	Synthesis, characterization and cytotoxic activity of Ga(III) complexes with asymmetric pyrazolyl-containing chelators Conference	13th International Conference on Biological Inorganic Chemistry
2007 - 2007	Chemical and biological evaluation of 153-Sm and 166-Ho complexes with tetraethylester of DOTP Meeting	7th international Symposium on Radiopharmaceutical Sciences
2006 - 2006	Ring annelated estranes as potential cancer diagnostic agents Meeting	8th Cross-Straits Symposium in Pusan
2006 - 2006	Radiolanthanide macrocyclic complexes as bone seeking agents: synthesis and biological evaluation Meeting	Medicinal Chemistry in the 21th Century
2006 - 2006	Radiolanthanide complexes with a novel bis(methylphosphonate) tetraazamacrocycle Meeting	9th International Symposium on Metal ions in Biology and Medicine
2006 - 2006	Synthetic estrane derived steroids as potential radiodiagnostics and drug delivery systems for minimal breast cancer Meeting	The Fukuoka Symposium - New Horizons in Natural Products and Biological Chemistries
2006 - 2006	Radiolanthanide complexes with tetraazamacrocycles bearing methylphosphonate pendant arms as bone seeking agents Symposium	13th European Symposium on Radiopharmacy and Radiopharmaceuticals
2006 - 2006	Mixed tetraazamacrocycles with phosphonate pendant arms: the influence of the number of phosphonate arms on the radiochemical and biological behaviour of their 153Sm and 166Ho complexes Symposium	7th International Symposium on Technetium in Chemistry and Nuclear Medicine
2006 - 2006	153Sm and 166Ho complexes with mixed tetraazamacrocycles: effect of the number of phosphonate pendant arms on bone targeting Workshop	COST Action D18, Lanthanide Chemistry for Diagnosis and Therapy
2005 - 2005	Biological evaluation of 153-Sm and 166-Ho complexes with macrocyclic ligands containing acetate pendant arms as potential agents for therapy Meeting	International Symposium on Trends in Radiopharmaceuticals (ISTR-2005)
2004 - 2004	Radiopharmaceuticals for targeted therapy: synthesis, radiolabelling and biological evaluation Congress	ICRS-10 RPS 2004, 21th Century Challenges in Radiation Protection and Shielding
2004 - 2004	In vitro and in vivo evaluation of 153Sm and 166Ho complexes with tetraazamacrocycles , effect of the incorporation of a pyridine head Workshop	COST Action D18, Lanthanides in Therapy: Particle Emitting Radiolanthanides and Stable Lanthanides with Radiation Induced by External Irradiation
2003 - 2003	Lanthanide complexes with 13-14-membered tetraazamacrocycles Meeting	7th FIGIPS Meeting in Inorganic Chemistry
2003 - 2003	Evaluation of radiolanthanide complexes as potential therapeutic agents Meeting	1º Workshop em Bioquímica Clínica
2003 - 2003	In vitro and in vivo evaluation of 153Sm and 166Ho complexes with macrocycles Symposium	11th European Symposium on Radiopharmacy and Radiopharmaceuticals
2002 - 2002	Complexação de 153-Sm com macrociclos do tipo tetraaza Meeting	18º Encontro Nacional da Sociedade Portuguesa de Química
2002 - 2002	Novel estrone compounds for radiolabeling Meeting	4st Cross Straits Symposium
2002 - 2002	Lanthanide macrocyclic complexes: radiochemical and chemical studies Conference	35th International Conference on Coordination Chemistry-ICCC 35
2002 - 2002	Composites peptides-steroids/alkaloids derived from estrones Conference	ORCHEM 2002
2000 - 2000	C-7 substituted estra-1,3,5(10),6-tetraenes as new radioligands for the estrogen receptor ER alpha as potential diagnostic tools for human breast cancer Meeting	11Th International Symposium on Supramolecular Chemistry
1999 - 1999	New radioligands for the estrogen receptor ER alpha as potential diagnostic tools for human breast cancer Meeting	1st Cross straits Symposium
1999 - 1999	Novel 186-Re complexes prepared using the irradiation conditions available at RPI. Synthesis, characterization and evaluation of their stability Meeting	International Symposium on Research Reactor Utilization, Safety and Management
1998 - 1998	Modulation of NADH ferricyanide reductase and phosphotyrosine phosphatase by high glucose levels Congress	11º Congresso Nacional de Bioquímica
1998 - 1998	Receptor phosphorylation as an important signal for activation of a NADH dehydrogenase in human erythrocytes by insulin Congress	4th European Congress of Endocrinology
1998 - 1998	Activation of a NADH fericyanide reductase in the human erythrocytes is mediated by phosphorylation reactions Conference	International Conference on Plasma Membrane Redox Systems
1997 - 1997	Proposta para valores de consenso para 87-Sr/86-Sr em carbonatos de estrôncio NBS-987 e SrN (E&A) Congress	4º Congresso de Geoquímica dos Países de Língua Portuguesa
1997 - 1997	Activação do sistema enzimático redox transmembranar dos eritrócitos humanos por agonistas beta adrenérgicos Meeting	Reunião da Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo
1996 - 1996	Regulation of a NADH dehydrogenase in the human erythrocytes by beta-adrenergic agonists Conference	Oxidative Stress and Redox Regulation: Cellular Signalling, Aids, Cancer and other Diseases Institut Pasteur, France
1995 - 1995	Metal ion requirement for DNA strand breakage by H2O2 in human leukocytes Congress	2º Congresso de Radicais Livres em Química Universidade do Porto Faculdade de Ciências, Portugal
1993 - 1993	Control of plasma membrane oxidoreductase in the human erythrocytes by hGH and insulin Congress	3rd European Congress of Endocrinology
1993 - 1993	Hormone control of NADH ferricyanide reductase activity in the human erythrocytes Congress	IX Congresso Nacional de Bioquímica
1993 - 1993	Somatotrophin effect on a transmembrane oxidoreductase system of the human erythrocytes Meeting	6th Meeting of the European Neuroendocrine Association
1993 - 1993	Geração de quinonas, semiquinonas e espécies activas de oxigénio durante oxidação da adrenalina pelas membranas do eritrócito humano Congress	Congresso de Radicais Livres em Química, Biologia e Medicina
1992 - 1992	Transplasma membrane redox mechanism in the human erythrocytes activated by catecholamines Congress	I Congresso Nacional de Neurociências
1992 - 1992	Sistema redox transmembranar, transdução hormonal e envelhecimento Meeting	VII Encontro sobre Envelhecimento Cerebral e Demências
1991 - 1991	Can a transmembranar redox system be a catecholamine transducing mechanism? Congress	IV Portuguese-Spanish Biochemistry Congress
1989 - 1989	Systema redox transmembranar no coração de rã e sua regulação por modificadores de sistemas de transporte catiónicos Meeting	X Reunião Nacional da Sociedade Portuguesa de Fisiologia
1989 - 1989	Sistema redox transmembranar, ferro e envelhecimento do sistema nervoso Meeting	IV Encontro sobre Envelhecimento do Sistema Nervoso e Demências
1988 - 1988	Transplasma membrane redox system (ferricyanide reductase) in the blood red cells and free radicals of oxygen Congress	III Portuguese-Spanish Biochemistry Congress
1988 - 1988	Possível papel das proteínas G no controlo das oxidoreductases do NADH da membrana celular Meeting	III Sessão Ordinária da Sociedade Portuguesa de Biologia
1988 - 1988	Ferricianeto reductase no coração de rã Meeting	IX Reunião da Sociedade Portuguesa de Fisiologia
1988 - 1988	Transferrin iron reductase, free radicals and aging Meeting	III Meeting on Aging Nervous System and Dementia
1988 - 1988	Transplasma membrane redox system in erythrocyte ghosts Workshop	NATO Advanced Workshop on Plasma Membrane Oxidoreductases in Control of Animal and Plant Growth
1988 - 1988	Sistema redox transmembranar no coração de rã: papel do cálcio e pH Meeting	II Sessão Ordinária da Sociedade Portuguesa de Biologia
1987 - 1987	Diaforase (fericianeto reductase) do glóbulo vermelho Congress	VIII Congresso Nacional de Bioquímica
1987 - 1987	Doseamento directo de cortisol no soro por radioimunoensaio Congress	IV Congresso Nacional de Medicina Nuclear
1986 - 1986	Constante de afinidade de um anticorpo, parâmetro importante para o desenvolvimento de um kit Meeting	Reunião Científica da Sociedade Portuguesa de Medicina Nuclear
1985 - 1985	Estudo da Ligação a uma fase sólida de alguns anti-T3 Congress	III Congresso Nacional de Medicina Nuclear
1983 - 1983	Estudo comparativo entre 198^Au e 109^Pd na forma de soluções coloidais Congress	II Congresso Nacional de Medicina Nuclear

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2017/06/23	Carboranylphosphinic acids: A new class of Purely Inorganic Ligands to generate Polynuclear Compounds and Multifunctional Nanohybrids Materials for Biomedical Applications (Thesis) Arguer	Elena Oleshkevich (PhD) Institut de Ciència de Materials de Barcelona, Spain
2017/05/03	The effect of bone collagen fragments on breast and prostate cancer (Thesis) Arguer	Bárbara Franco Andrade Góis (Master) Universidade de Lisboa Instituto Superior Técnico, Portugal

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2017/06/19 - 2017/06/22	Materials for Biomedical Applications: "in vitro" evaluation	International Summer School on Materials for Biomedical Application (MATBIO2017)	Institut de Ciència de Materials de Barcelona, Spain
2004 - 2011	Interação da radiação com a matéria e deteção da radiação; Radiobiologia, efeitos biológicos das radiações.	Química Inorgânica Biomédica: Aplicações em Diagnóstico e Terapia	Universidade de Lisboa Faculdade de Ciências, Portugal
2001 - 2011	Radiolabeling techniques	(Licenciatura)	Instituto Tecnológico e Nuclear Departamento de Radioisótopos, Portugal
2009/10 - 2009/10	Radioimunoensaios	Proteção Radiológica em Laboratórios de Radioimunoensaio (Curso de Especialização Tecnológica)	Hospital Garcia de Orta EPE, Portugal
2003/02/10 - 2003/02/14	Desenvolvimento de complexos radioactivos como potenciais agentes terapêuticos	(Licenciatura)	Instituto Tecnológico e Nuclear Departamento de Radioisótopos, Portugal

Journal scientific committee

	Journal title (ISSN)	Publisher
2019 - 2019	Journal of Inorganic Biochemistry
2018 - 2018	Boron-Based Compounds: Potential and Emerging Applications in Medicine (book)	Wiley Online Library
2017 - 2017	Journal of Inorganic Biochemistry (0162-0134)	Elsevier
2015 - 2015	Bioorganic & Medicinal Chemistry (0968-0896)	Elsevier
2015 - 2015	Bioorganic & Medicinal Chemistry (0968-0896)	Elsevier
2014 - 2014	Molecules (1420-3049)	MDPI AG
2014 - 2014	JBIC Journal of Biological Inorganic Chemistry (1432-1327)	Springer-Verlag
2014 - 2014	International Journal of Molecular Sciences	MDPI

Distinctions

Other distinction

2013	Best poster prize
1997	Ernesto Roma-Boehringer Mannheim F Hoffmann-La Roche AG, Switzerland