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Identification

Personal identification

Full name
håvard jenssen

Citation names

  • Jenssen, Håvard

Author identifiers

Ciência ID
1C15-8F93-BB81
ORCID iD
0000-0003-0007-0335
Education
Degree Classification
2003 - 2005
Concluded
Dr. Sc. in Peptide chemistry (Doctor of Philosophy)
Major in Peptide chemistry
University of Tromsø , Norway
1997 - 1999
Concluded
C.E. in biotechnology (Postgraduate Certificate)
Major in biotechnology
University of Tromsø , Norway
1994 - 1997
Concluded
B.Sc in biochemistry (Bachelor)
Major in Biochemistry
College of Engineering , Norway

University of Oslo-College of Engineering, Norway
Affiliation

Science

Category
Host institution
Employer
2009/08/01 - Current Principal Investigator (Research) Roskilde Universitet, Denmark
2008 - 2009 Research Assistant (Research) The University of British Columbia Centre for Microbial Diseases and Immunity Research, Canada
2005 - 2007 Researcher (Research) The University of British Columbia Centre for Microbial Diseases and Immunity Research, Canada

Positions / Appointments

Category
Host institution
Employer
2000 - 2002 Research Associate Dept. of Microbiology, University Hospital of North Norway, Norway
Projects

Grant

Designation Funders
2018 - 2018 7th International Meeting on Antimicrobial Peptides
1
Researcher
University of Roskilde, Denmark
2018 - 2018 Diabetic Wound Healing Workshop
20181004
Researcher
University of Roskilde, Denmark
Concluded
2018 - 2018 Hyaluronic acid hydrogels, antimicrobial peptoids (AMPETOIDs) and innate defence regulators (IDRs); exploration of their joint potential in healing of infected chronic wounds
8073-00032B
Researcher
University of Roskilde, Denmark
Concluded
2018 - 2018 Influence of Cyclization on Antimicrobial, Antibiofilm, Toxicity and Immune modulation Profiles of Peptides and Peptoids
5867
Researcher
University of Roskilde, Denmark
Concluded
2016 - 2016 Towards Stable Peptide-Based Therapeutics for Adjunctive Treatment of Tuberculosis
1
Researcher
University of Roskilde, Denmark
Concluded
2016 - 2016 Antimicrobial peptides seen by Neutrons: from basic mechanisms to the next generation antibiotics
82004
Researcher
University of Roskilde, Denmark
Concluded
2015 - 2015 Combination therapy synergistically accelerates diabetic wound closure
1
Researcher
University of Roskilde, Denmark
Ongoing
2014 - 2014 Hidradenitis suppurativa microbiology
1
Researcher
University of Roskilde, Denmark
2014 - 2014 NGS diagnostics of hepatitis C virus
1
Researcher
University of Roskilde, Denmark
Concluded
2014 - 2014 Peptide QSAR
1
Researcher
University of Roskilde, Denmark
Concluded
2014 - 2014 Tuning peptides into drugs
4005-00029
Researcher
University of Roskilde, Denmark
2014 - 2014 RUC PhD scholarship
4005-00029
Researcher
University of Roskilde, Denmark
Concluded
2013 - 2013 Peptidomimetics in Drug Development
1828
Researcher
University of Roskilde, Denmark
Concluded
2013 - 2013 The Involvement of Fimbriae in Infections caused by Opportunistic Gram-Negative Pathogens and the Discovery of Potential Anti-Virulence Peptides
1
Researcher
University of Roskilde, Denmark
Concluded
2013 - 2013 Flavanoid production and biological activity evaluation
1
Researcher
University of Roskilde, Denmark
Concluded
2012 - 2012 Exploration of Lanthibiotics – a conserved defence component in many bacteria
12-132613
Researcher
University of Roskilde, Denmark
Concluded
2011 - 2011 Development of novel anti-infective peptides by sophisticated computer-aided modeling
11-106387
Researcher
University of Roskilde, Denmark
2011 - 2011 RUC PhD scholarship
10-085287
Supervisor
University of Roskilde, Denmark
Concluded
2010 - 2010 Peptoid-based antimicrobials – what gives rise to their activity?”
10-085287
Researcher
University of Roskilde, Denmark
Concluded
2009 - 2009 Advancement of Bioactive Peptides Derived from Mother’s Milk
123
Researcher
University of Roskilde, Denmark
Concluded
Outputs

Publications

Book
  1. Jenssen, Håvard. Therapeutic potential of HDPs as immunomodulatory agents.. Methods Mol Biol.. 2010.
  2. Jenssen, H.. Antimicrobial activity of lactoferrin and lactoferrin derived peptides. 2009.
  3. Jenssen, H.; Aspmo, S.I.. Serum stability of peptides. 2008.
    10.1007/978-1-59745-419-3_10
Book chapter
  1. Fjell, C.D.; Jenssen, H.; Hancock, R.E.W.; Cherkasov, A.. "Quantitative structure-activity relationship-based discovery of antimicrobial peptides active against multidrug-resistant bacteria". 187-207. 2012.
  2. Sun, Haiyan; Jensse, Hvard. "Milk Derived Peptides with Immune Stimulating Antiviral Properties". In Milk Protein. InTech, 2012.
    10.5772/50158
Conference abstract
  1. G.P.B. Carretero; J. Paulino; C. Alvarez; Håvard Jenssen; S. Schreier. "Binding of peptides from the N-termini of sticholysins to lipid membranes". 2014.
  2. Biljana Mojsoska; Håvard Jenssen. "Peptidomimetics in antimcrobial drug development". 2014.
  3. Håvard Jenssen; J. Kindrachuk; M. Elliott; M. Waldbrook; K. Hilpert; C. Fjell; R.E.W. Hancock. "Systematic design and screening of immune modulating innate defence regulator peptides". 2010.
    10.1002/psc.1303
  4. M. Mehrabian; Håvard Jenssen; A. Kyani. "QSAR modeling of calcitonin gene-related peptide antagonists". 2010.
Journal article
  1. Foteini Tsakou; Rosa Jersie-Christensen; Håvard Jenssen; Biljana Mojsoska. "The Role of Proteomics in Bacterial Response to Antibiotics". Pharmaceuticals 13 9 (2020): 214-214. https://doi.org/10.3390/ph13090214.
    10.3390/ph13090214
  2. Laura Daniela Martinenghi; Rie Jønsson; Torben Lund; Håvard Jenssen. "Isolation, Purification, and Antimicrobial Characterization of Cannabidiolic Acid and Cannabidiol from Cannabis sativa L.". Biomolecules 10 6 (2020): 900-900. https://doi.org/10.3390/biom10060900.
    10.3390/biom10060900
  3. Jasmeet Singh Khara; Biljana Mojsoska; Devika Mukherjee; Paul R Langford; Brian D. Robertson; Håvard Jenssen; Pui Lai Rachel Ee; Sandra M. Newton. "Ultra-short antimicrobial peptoids show propensity for membrane activity against multi-drug resistant Mycobacterium tuberculosis". Frontiers in Microbiology 2020 11 (2020): 417-417. https://forskning.ruc.dk/en/publications/a2900db9-f24e-4de3-b822-ca6220aca65e.
    10.3389/fmicb.2020.00417
  4. Greco, I.; Molchanova, N.; Holmedal, E.; Jenssen, H.; Hummel, B.D.; Watts, J.L.; Håkansson, J.; Hansen, P.R.; Svenson, J.. "Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides". Scientific Reports 10 1 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85089063737&partnerID=MN8TOARS.
    10.1038/s41598-020-69995-9
  5. Baer, B.; Veldhuizen, E.J.A.; Molchanova, N.; Jekhmane, S.; Weingarth, M.; Jenssen, H.; Lin, J.S.; et al. "Optimizing Exogenous Surfactant as a Pulmonary Delivery Vehicle for Chicken Cathelicidin-2". Scientific Reports 10 1 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85086236002&partnerID=MN8TOARS.
    10.1038/s41598-020-66448-1
  6. Pietsch, F.; O'Neill, A.J.; Ivask, A.; Jenssen, H.; Inkinen, J.; Kahru, A.; Ahonen, M.; Schreiber, F.. "Selection of resistance by antimicrobial coatings in the healthcare setting". Journal of Hospital Infection 106 1 (2020): 115-125. http://www.scopus.com/inward/record.url?eid=2-s2.0-85089063744&partnerID=MN8TOARS.
    10.1016/j.jhin.2020.06.006
  7. Persson, B.D.; Lenman, A.; Frängsmyr, L.; Schmid, M.; Ahlm, C.; Plückthun, A.; Jenssen, H.; Arnberg, N.. "Lactoferrin-Hexon Interactions Mediate CAR-Independent Adenovirus Infection of Human Respiratory Cells". Journal of virology 94 14 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85087533884&partnerID=MN8TOARS.
    10.1128/JVI.00542-20
  8. Lone, A.; Arnous, A.; Hansen, P.R.; Mojsoska, B.; Jenssen, H.. "Synthesis of Peptoids Containing Multiple Nhtrp and Ntrp Residues: A Comparative Study of Resin, Cleavage Conditions and Submonomer Protection". Frontiers in Chemistry 8 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85084581171&partnerID=MN8TOARS.
    10.3389/fchem.2020.00370
  9. Mahmoud Abdel-Hamid; Ehab Romeih; Paola Saporito; Ali Osman; Ramona Valentina Mateiu; Biljana Mojsoska; Håvard Jenssen. "Camel milk whey hydrolysate inhibits growth and biofilm formation of Pseudomonas aeruginosa PAO1 and methicillin-resistant Staphylococcus aureus". Food Control 111 (2020): https://forskning.ruc.dk/en/publications/59049842-ccb0-4661-b831-89e986d36a28.
    10.1016/j.foodcont.2019.107056
  10. Abdullah Lone; Thomas T. Thomsen; Josefine Eilsø Nielsen; Peter W. Thulstrup; Rasmus N. Klitgaard; Anders Løbner-Olesen; Reidar Lund; Håvard Jenssen; Paul R. Hansen. "Structure-Activity Study of an All-d Antimicrobial Octapeptide D2D". Molecules (2019): https://doi.org/10.3390/molecules24244571.
    10.3390/molecules24244571
  11. Michelle V. Mouritzen; Athina Andrea; Katrine Qvist; Steen S. Poulsen; Håvard Jenssen. "Immunomodulatory potential of Nisin A with application in wound healing". Wound Repair and Regeneration (2019): https://doi.org/10.1111/wrr.12743.
    10.1111/wrr.12743
  12. Paola Saporito; Biljana Mojsoska; Anders Løbner Olesen; Håvard Jenssen. "Antibacterial mechanisms of GN-2 derived peptides and peptoids against Escherichia coli". Biopolymers 110 6 (2019): https://doi.org/10.1002/bip.23275.
    10.1002/bip.23275
  13. João Moura; Anja Elaine Sørensen; Rikke Svendsen; Lina Carvalho; Ermelindo C. Leal; Rie Juul Willemoes; Per Trolle Jørgensen; et al. "MicroRNA-155 inhibition restores Fibroblast Growth Factor 7 expression in diabetic skin and decreases wound inflammation". Scientific Reports 2019 9 (2019): https://forskning.ruc.dk/en/publications/c314a8c8-a3b3-4f38-ad0b-a797a18520af.
    10.1038/s41598-019-42309-4
  14. Athina Andrea; Karen Krogfelt; Håvard Jenssen. "Methods and Challenges of Using the Greater Wax Moth (Galleria mellonella) as a Model Organism in Antimicrobial Compound Discovery". Microorganisms (2019): https://doi.org/10.3390/microorganisms7030085.
    10.3390/microorganisms7030085
  15. Josefine Eilsø Nielsen; Tania Kjellerup Lind; Abdullah Lone; Yuri Gerelli; Paul Robert Hansen; Håvard Jenssen; Marité Cárdenas; Reidar Lund. "A biophysical study of the interactions between the antimicrobial peptide indolicidin and lipid model systems". B B A - Biomembranes 1861 7 (2019): 1355-1364. https://forskning.ruc.dk/en/publications/1512977b-c7dc-47f4-a79c-7a7f59e62c11.
    10.1016/j.bbamem.2019.04.003
  16. Martin Schou Pedersen; Sarah Mollerup; Lone Gilmor Nielsen; Håvard Jenssen; Jens Bukh; Kristian Schønning. "Genome Sequence of an Unknown Subtype of Hepatitis C Virus Genotype 6". Microbiology Resource Announcements 8 (2019): https://forskning.ruc.dk/en/publications/6f53ba77-ecc3-467d-9192-e7b5dc0cee44.
    10.1128/MRA.01030-19
  17. Christine B. Ardon; E.P. Prens; Kurt Fuursted; R.N. Ejaz; J. Shailes; Håvard Jenssen; Gregor B.E. Jemec. "Biofilm production and antibiotic susceptibility of Staphylococcus epidermidis strains from Hidradenitis Suppurativa lesions". Journal of the European Academy of Dermatology and Venereology 33 1 (2019): 170-177. https://forskning.ruc.dk/en/publications/8f7a2005-7647-4b45-ac03-13b86847d57a.
    10.1111/jdv.15183
  18. C.B Ardon; E.P. Prens; J. Tkadlec; Kurt Fuursted; Sali Abourayale; G.B.E. Jemec; Håvard Jenssen. "Virulent Staphylococcus lugdunensis with limited genetic diversity in hidradenitis suppurativa lesions". Journal of the European Academy of Dermatology and Venereology 33 6 (2019): e248-e250. https://forskning.ruc.dk/en/publications/c0c809f3-c78b-4379-8118-370ac31d1b98.
    10.1111/jdv.15523
  19. Paola Saporito; Michelle Vang Mouritzen; Anders Løbner-Olesen; Håvard Jenssen. "LL-37 fragments have antimicrobial activity against Staphylococcus epidermidis biofilms and wound healing potential in HaCaT cell line". Journal of Peptide Science 24 7 (2018): e3080-e3080. https://doi.org/10.1002/psc.3080.
    10.1002/psc.3080
  20. Håvard Jenssen. "7th International Meeting on Antimicrobial Peptides". Journal of Peptide Science 24 7 (2018): e3116-e3116. https://doi.org/10.1002/psc.3116.
    10.1002/psc.3116
  21. Michelle V. Mouritzen; Sali Abourayale; Rooshanie Ejaz; Christine B. Ardon; Eugenia Carvalho; Louise T. Dalgaard; Martin Roursgaard; Håvard Jenssen. "Neurotensin, substance P, and insulin enhance cell migration". Journal of Peptide Science 24 7 (2018): e3093-e3093. https://doi.org/10.1002/psc.3093.
    10.1002/psc.3093
  22. Athina Andrea; Natalia Molchanova; Håvard Jenssen. "Antibiofilm Peptides and Peptidomimetics with Focus on Surface Immobilization". Biomolecules 8 2 (2018): 27-27. https://doi.org/10.3390/biom8020027.
    10.3390/biom8020027
  23. Martin Schou Pedersen; Ulrik Fahnøe; Thomas Arn Hansen; Anders Gorm Pedersen; Håvard Jenssen; Jens Bukh; Kristian Schønning. "A near full-length open reading frame next generation sequencing assay for genotyping and identification of resistance-associated variants in hepatitis C virus". Journal of Clinical Virology 105 (2018): 49-56. https://forskning.ruc.dk/en/publications/4aa4f7c7-1bfd-4776-b9de-8fb77c945021.
    10.1016/j.jcv.2018.05.012
  24. Gustavo Battesini Carretero; Eduardo F. Vicente; Eduardo M. Cilli; Carlos M. Alvarez; Håvard Jenssen; Shirley Schreier. "Dissecting the mechanism of action of actinoporins. Role of the N-terminal amphipathic a-helix in membrane binding and pore activity of sticholysins I and II". P L o S One 13 8 (2018): https://forskning.ruc.dk/en/publications/1f86f404-daf3-4905-9c71-4113ece89290.
    10.1371/journal.pone.0202981
  25. Michelle Vang Mouritzen; Håvard Jenssen. "Optimized Scratch Assay for In Vitro Testing of Cell Migration with an Automated Optical Camera". Journal of Visualized Experiments 2018 138 (2018): https://forskning.ruc.dk/en/publications/8a411ae5-c236-46bb-ae78-27ff585da9cb.
    10.3791/57691
  26. Beata Joanna Lehka; Michael Eichenberger; Walden Emil Bjørn Yoshimoto; Katherina Garcia Vanegas; Nicolaas Buijs; Niels Bjerg Jensen; Jane Dannow Dyekjær; et al. "Improving heterologous production of phenylpropanoids in Saccharomyces cerevisiae by tackling an unwanted side reaction of Tsc13, an endogenous double bond reductase". FEMS Yeast Research 17 1 (2017): https://forskning.ruc.dk/en/publications/d75bcaae-b0f6-41d1-be7d-d54d17c17a46.
    10.1093/femsyr/fox004
  27. Rie Jønsson; Bing Liu; Carsten Struve; Yi Yang; René Jørgensen; Yingqi Xu; Håvard Jenssen; Karen A. Krogfelt; Steve Matthews. "Structural and functional studies of Escherichia coli aggregative adherence fimbriae (AAF/V) reveal a deficiency in extracellular matrix binding". B B A - Proteins and Proteomics 1865 3 (2017): 304–311-304–311. https://forskning.ruc.dk/en/publications/248827d4-416d-4698-afe3-8fec7bc31f47.
    10.1016/j.bbapap.2016.11.017
  28. Rie Jønsson; Carsten Struve; Erik J. Boll; Nadia Boisen; Katrine Grimstrup Joensen; Camilla A. Sørensen; Betina H. Jensen; et al. "A novel pAA virulence plasmid encoding toxins and two distinct variants of the fimbriae of enteroaggregative Escherichia coli". Frontiers in Microbiology 8 (2017): 263-263. https://forskning.ruc.dk/en/publications/4679b5c2-1990-46d6-bf6e-6f099b444a7c.
    10.3389/fmicb.2017.00263
  29. Biljana Mojsoska; Gustavo Battesini Carretero; Sylvester Larsen; Ramona Valentina Mateiu; Håvard Jenssen. "Peptoids successfully inhibit the growth of gram negative E. coli causing substantial membrane damage". Scientific Reports 7 (2017): 42332-42332. https://forskning.ruc.dk/en/publications/83e2f9c5-1222-4fce-a48b-03bc5c6502dc.
    10.1038/srep42332
  30. Rie Jønsson; Carsten Struve; Håvard Jenssen; Karen A. Krogfelt. "The wax moth Galleria mellonella as a novel model system to study Enteroaggregative Escherichia coli pathogenesis". Virulence 8 8 (2017): 1894-1899. https://forskning.ruc.dk/en/publications/e55ba437-c69c-4df7-b9d0-2a88f264a96f.
    10.1080/21505594.2016.1256537
  31. Biljana Mojsoska; Hanne Mørck Nielsen; Håvard Jenssen. "Antimicrobial activity of GN peptides and their mode of action". Biopolymers 106 2 (2016): 172-183. https://forskning.ruc.dk/en/publications/b517aa2d-c42b-414a-ad08-d208041b0255.
    10.1002/bip.22796
  32. Thomas T. Thomasen; Biljana Mojsoska; Joao C. S Cruz; Stefano Donadio; Håvard Jenssen; Anders Løbner-Olesen; Kim Furbo Rewitz. "The Lantibiotic NAI-107 Efficiently Rescues Drosophila melanogaster from Infection with Methicillin-Resistant Staphylococcus aureus USA300". Antimicrobial Agents and Chemotherapy 60 9 (2016): 5427-5436. https://forskning.ruc.dk/en/publications/2fe0e8e8-d296-4031-95f6-0cd7011476f9.
    10.1128/AAC.02965-15
  33. Mahmoud Abdel-Hamid; Hanan A. Goda; Cristian De Gobba; Håvard Jenssen; Ali Osman. "Antibacterial activity of papain hydrolysed camel whey and its fractions". International Dairy Journal 61 (2016): 91-98. https://forskning.ruc.dk/en/publications/89ec4804-55ba-471e-97d7-1754ca3c6405.
    10.1016/j.idairyj.2016.04.004
  34. Ann M. Czyzewski; Håvard Jenssen; Christopher D. Fjell; M. Waldbrook; Nathaniel P. Chongsiriwatana; Eddie Yuen; Robert E. W. Hancock; Annelise E. Barron. "In Vivo, In Vitro, and In Silico Characterization of Peptoids as Antimicrobial Agents". P L o S One 11 2 (2016): https://forskning.ruc.dk/en/publications/24212c01-32f5-40c9-acb0-ac07ee9ae9e5.
    10.1371/journal.pone.0135961
  35. Biljana Mojsoska; Ronald N. Zuckermann; Håvard Jenssen. "Structure-Activity Relationship Study of Novel Peptoids That Mimic the Structure of Antimicrobial Peptides". Antimicrobial Agents and Chemotherapy 59 7 (2015): https://forskning.ruc.dk/en/publications/a81ff8bb-eeb5-433c-9fc6-6f475c86dda9.
    10.1128/AAC.00237-15
  36. Hans Christian Ring; Peter Riis Mikkelsen; Iben Marie Miller; Håvard Jenssen; Kurt Fuursted; Ditte Marie Saunte; Gregor Jemec. "The bacteriology of hidradenitis suppurativa". Experimental Dermatology 24 10 (2015): 727-731. https://forskning.ruc.dk/en/publications/e9d1ebb8-6173-4937-925d-5b50cb1545b6.
    10.1111/exd.12793
  37. Rie Jønsson; Carsten Struve; Nadia Boisen; Ramona Valentina Mateiu; Araceli E. Santiago; Håvard Jenssen; James P. Nataro; Karen A. Krogfelt. "Novel Aggregative Adherence Fimbria Variant of Enteroaggregative Escherichia coli". Infection and Immunity 83 4 (2015): 1396–1405-1396–1405. https://forskning.ruc.dk/en/publications/3f3c1238-b4f3-43e6-9645-c95dff9a900e.
    10.1128/IAI.02820-14
  38. Mojsoska, B.; Jenssen, H.. "Peptides and peptidomimetics for antimicrobial drug design". Pharmaceuticals 8 3 (2015): 366-415. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937921183&partnerID=MN8TOARS.
    10.3390/ph8030366
  39. Håvard Jenssen; Andrey Shestakov; Robert E. W Hancock; Inger Nordström; Kristina Eriksson. "Synthetic analogues of bovine bactenecin dodecapeptide reduce herpes simplex virus type 2 infectivity in mice". Antiviral Research 100 2 (2013): 455-459. https://forskning.ruc.dk/en/publications/29ba4a71-d67b-4e42-b869-406566bde164.
    10.1016/j.antiviral.2013.08.019
  40. Kindrachuk, J.; Jenssen, H.; Elliott, M.; Nijnik, A.; Magrangeas-Janot, L.; Pasupuleti, M.; Thorson, L.; et al. "Manipulation of innate immunity by a bacterial secreted peptide: Lantibiotic nisin Z is selectively immunomodulatory". Innate Immunity 19 3 (2013): 315-327. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877744600&partnerID=MN8TOARS.
    10.1177/1753425912461456
  41. Lars Steinstraesser; Tobias Hirsch; Matthias Schulte; Maximilian Kueckelhaus; Frank Jacobsen; Evgeniija A. Mersch; Ingo Stricker; et al. "Innate Defense Regulator Peptide 1018 in Wound Healing and Wound Infection". P L o S One 7 8 (2012): https://forskning.ruc.dk/en/publications/d07f8a6f-ffa3-4ee8-a7e0-4d25594e7b94.
    10.1371/journal.pone.0039373
  42. Andreas Skovgård Jacobsen; Håvard Jenssen. "Human cathelicidin LL-37 prevents bacterial biofilm formation". Future Medicinal Chemistry 4 12 (2012): 1587-1599. https://forskning.ruc.dk/en/publications/a4422b71-0ae7-4b6b-b3a0-f87a7ea74aa1.
    10.4155/FMC.12.97
  43. Erlend Kristiansen; Casper Wilkens; Bjarne Vincents; Dennis Friis; Anders Blomkild Lorentzen; Håvard Jenssen; Anders Løbner-Olesen; Hans Ramløv. "Hyperactive antifreeze proteins from longhorn beetles". Journal of Insect Physiology 58 11 (2012): 1502-1510. https://forskning.ruc.dk/en/publications/912f564c-8b85-4cad-aa79-a096b06d3d7c.
    10.1016/j.jinsphys.2012.09.004
  44. Andrey Shestakov; Håvard Jenssen; Inger Nordström; Kristina Eriksson. "Lactoferricin but not lactoferrin inhibit herpes simplex virus type 2 infection in mice". Antiviral Research 93 3 (2012): 340-345. https://forskning.ruc.dk/en/publications/d1727d4e-244f-44c6-b18e-f57699b8defa.
    10.1016/j.antiviral.2012.01.003
  45. Håvard Jenssen; Mohadeseh Mehrabian; Anahita Kyani. "Quantitative Structure-Activity Relationships and Docking Studies of Calcitonin Gene-Related Peptide Antagonists". Chemical Biology and Drug Design (Print) 79 2 (2012): 166-176. https://forskning.ruc.dk/en/publications/00b523a0-7061-410e-8a6c-2fb06e1e578f.
    10.1111/j.1747-0285.2011.01252.x
  46. Luca Fernandez; Håvard Jenssen; Manjeet Bains; Irith Wiegand; James W. Gooderham; Robert E.W. Hancock. "The Two-Component System CprRS Senses Cationic Peptides and Triggers Adaptive Resistance in Pseudomonas aeruginosa Independently of ParRS". Antimicrobial Agents and Chemotherapy 56 12 (2012): 6212-6222. https://forskning.ruc.dk/en/publications/d698a006-a314-4c66-811d-ac02175cc211.
    10.1128/AAC.01530-12
  47. Christopher D. Fjell; Håvard Jenssen; Warren A. Cheung; Robert E. W. Hancock; Artem Cherkasov. "Optimization of antibacterial peptides by genetic algorithms and cheminformatics". Chemical Biology and Drug Design (Print) 77 1 (2011): 48-56. https://forskning.ruc.dk/en/publications/a1043b1f-0c64-4e7c-9915-ae1bc89210b9.
    10.1111/j.1747-0285.2010.01044.x
  48. Apollinaire Tsopmo; Andrea Romanowski; Lyness Banda; Jean Claude Lavoie; Håvard Jenssen; James K. Friel. "Novel anti-oxidative peptides from enzymatic digestion of human milk". Food Chemistry 126 3 (2011): 1138-43. https://forskning.ruc.dk/en/publications/6b0eb3d8-7a22-482e-b8ec-8c2af9e3be8e.
    10.1016/j.foodchem.2010.11.146
  49. Miriam A. Lynn; Jason Kindrachuk; Alexandra K. Marr; Håvard Jenssen; Nelly Panté; Melissa R. Elliott; Scott Napper; Robert E. Hancock; W. Robert McMaster. "Effect of BMAP-28 antimicrobial peptides on Leishmania major promastigote and amastigote growth". P L o S Neglected Tropical Diseases (Online) 5 5 (2011): e1141-e1141. https://forskning.ruc.dk/en/publications/c70ece8a-137a-4f11-ba07-dfa8f1af1a1b.
    10.1371/journal.pntd.0001141
  50. Godballe, T.; Nilsson, L.L.; Petersen, P.D.; Jenssen, H.. "Antimicrobial ß-Peptides and a-Peptoids". Chemical Biology and Drug Design 77 2 (2011): 107-116. http://www.scopus.com/inward/record.url?eid=2-s2.0-79251509263&partnerID=MN8TOARS.
    10.1111/j.1747-0285.2010.01067.x
  51. Jenssen, H.. "Descriptors for antimicrobial peptides". Expert Opinion on Drug Discovery 6 2 (2011): 171-184. http://www.scopus.com/inward/record.url?eid=2-s2.0-79251524952&partnerID=MN8TOARS.
    10.1517/17460441.2011.545817
  52. Michal Wieczorek; Håvard Jenssen; Jason Kindrachuk; Walter R.P. Scott; Melissa Elliott; Kai Hilpert; John T.J. Cheng; Robert E.W. Hancock; Suzana K. Straus. "Structural Studies of a Peptide with Immune Modulating and Direct Antimicrobial Activity". Chemistry & Biology 17 9 (2010): 970-980. https://forskning.ruc.dk/en/publications/74784e39-9574-4180-9910-4329bd079d91.
    10.1016/j.chembiol.2010.07.007
  53. Mehdi Kazemzadeh-Narbat; Jason Kindrachuk; Ke Duan; Håvard Jenssen; Robert E.W. Hancock; Rizhi Wang. "Antimicrobial peptides on calcium phosphate-coated titanium for the prevention of implant-associated infections". Biomaterials 31 36 (2010): 9519-9526. https://forskning.ruc.dk/en/publications/48317a28-a8de-4884-8289-c880355745f9.
    10.1016/j.biomaterials.2010.08.035
  54. John T.J. Cheng; John D. Hale; Jason Kindrachuk; Håvard Jenssen; Melissa Elliott; Robert E.W. Hancock; Suzana K. Straus. "Importance of Residue 13 and the C-Terminus for the Structure and Activity of the Antimicrobial Peptide Aurein 2.2". Biophysical Journal 99 9 (2010): 2926-2935. https://forskning.ruc.dk/en/publications/1d58d42a-2e82-4ef8-a5bd-262d3669a631.
    10.1016/j.bpj.2010.08.077
  55. Anastasia Nijnik; Laurence Madera; Shuhua Ma; Matthew Waldbrook; Melissa R. Elliott; Donna M. Easton; Matthew L. Mayer; et al. "Synthetic Cationic Peptide IDR-1002 Provides Protection against Bacterial Infections through Chemokine Induction and Enhanced Leukocyte Recruitment". Journal of Immunology 184 5 (2010): 2539–2550-2539–2550. https://forskning.ruc.dk/en/publications/8e711ed9-124a-43fb-8f51-87f01cd0dcd0.
    10.4049/jimmunol.0901813
  56. B. Bommarius; Håvard Jenssen; M. Elliott; J. Kindrachuk; Mukesh Pasupuleti; H. Gieren; K.-E. Jaeger; R.E.W. Hancock; D. Kalman. "Cost-effective expression and purification of antimicrobial and host defense peptides in Escherichia coli". Peptides 31 11 (2010): 1957-1965. https://forskning.ruc.dk/en/publications/4a1ade25-743c-4883-94d4-adb535e30594.
    10.1016/j.peptides.2010.08.008
  57. Fjell, C.D.; Hancock, R.E.W.; Jenssen, H.. "Computer-aided design of antimicrobial peptides". Current Pharmaceutical Analysis 6 2 (2010): 66-75. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952917455&partnerID=MN8TOARS.
    10.2174/157341210791202645
  58. Cheng, J.T.J.; Hale, J.D.; Kindrachuk, J.; Jenssen, H.; Elliott, M.; Hancock, R.E.W.; Straus, S.K.. "Erratum: Importance of residue 13 and the C-terminus for the structure and activity of the antimicrobial peptide aurein 2.2 (Biophysical Journal (2010) 99 (2926-2935))". Biophysical Journal 99 12 (2010): 4078-4078. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650120898&partnerID=MN8TOARS.
    10.1016/j.bpj.2010.11.026
  59. Jenssen, H.; Hancock, R.E.. "Therapeutic potential of HDPs as immunomodulatory agents.". Methods in molecular biology (Clifton, N.J.) 618 (2010): 329-347. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950482392&partnerID=MN8TOARS.
    10.1007/978-1-60761-594-1_20
  60. Håvard Jenssen. "Clinical development of peptide antibiotics". Pharmachem 10 (2009): 22-26. https://forskning.ruc.dk/en/publications/b807ba80-ef2b-11de-9cda-000ea68e967b.
  61. Jenssen, H.; Hancock, R.E.W.. "Antimicrobial properties of lactoferrin". Biochimie 91 1 (2009): 19-29. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149113170&partnerID=MN8TOARS.
    10.1016/j.biochi.2008.05.015
  62. Kovacs-Nolan, J.; Latimer, L.; Landi, A.; Jenssen, H.; Hancock, R.E.W.; Babiuk, L.A.; van Drunen Littel-van den Hurk, S.. "The novel adjuvant combination of CpG ODN, indolicidin and polyphosphazene induces potent antibody- and cell-mediated immune responses in mice". Vaccine 27 14 (2009): 2055-2064. http://www.scopus.com/inward/record.url?eid=2-s2.0-61549107999&partnerID=MN8TOARS.
    10.1016/j.vaccine.2009.01.118
  63. Hilpert, K.; Elliott, M.; Jenssen, H.; Kindrachuk, J.; Fjell, C.D.; Körner, J.; Winkler, D.F.H.; et al. "Screening and Characterization of Surface-Tethered Cationic Peptides for Antimicrobial Activity". Chemistry and Biology 16 1 (2009): 58-69. http://www.scopus.com/inward/record.url?eid=2-s2.0-58549117162&partnerID=MN8TOARS.
    10.1016/j.chembiol.2008.11.006
  64. Kindrachuk, J.; Jenssen, H.; Elliott, M.; Townsend, R.; Nijnik, A.; Lee, S.F.; Gerdts, V.; et al. "A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity". Vaccine 27 34 (2009): 4662-4671. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649494271&partnerID=MN8TOARS.
    10.1016/j.vaccine.2009.05.094
  65. Jenssen, H.. "Therapeutic approaches using host defence peptides to tackle herpes virus infections". Viruses 1 3 (2009): 939-964. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861370079&partnerID=MN8TOARS.
    10.3390/v1030939
  66. Cherkasov, A.; Hilpert, K.; Jenssen, H.; Fjell, C.D.; Waldbrook, M.; Mullaly, S.C.; Volkmer, R.; Hancock, R.E.W.. "Use of artificial intelligence in the design of small peptide antibiotics effective against a broad spectrum of highly antibiotic-resistant superbugs". ACS Chemical Biology 4 1 (2009): 65-74. http://www.scopus.com/inward/record.url?eid=2-s2.0-60749130267&partnerID=MN8TOARS.
    10.1021/cb800240j
  67. Fjell, C.D.; Jenssen, H.; Hilpert, K.; Cheung, W.A.; Panté, N.; Hancock, R.E.W.; Cherkasov, A.. "Identification of novel antibacterial peptides by chemoinformatics and machine learning". Journal of Medicinal Chemistry 52 7 (2009): 2006-2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-64549125571&partnerID=MN8TOARS.
    10.1021/jm8015365
  68. Marr, A.K.; Jenssen, H.; Moniri, M.R.; Hancock, R.E.W.; Panté, N.. "Bovine lactoferrin and lactoferricin interfere with intracellular trafficking of Herpes simplex virus-1". Biochimie 91 1 (2009): 160-164. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149140247&partnerID=MN8TOARS.
    10.1016/j.biochi.2008.05.016
  69. Jenssen, H.; Fjell, C.D.; Cherkasov, A.; Hancock, R.E.W.. "QSAR modeling and computer-aided design of antimicrobial peptides". Journal of Peptide Science 14 1 (2008): 110-114. http://www.scopus.com/inward/record.url?eid=2-s2.0-38849155828&partnerID=MN8TOARS.
    10.1002/psc.908
  70. Fjell, C.D.; Jenssen, H.; Fries, P.; Aich, P.; Griebel, P.; Hilpert, K.; Hancock, R.E.W.; Cherkasov, A.. "Identification of novel host defense peptides and the absence of a-defensins in the bovine genome". Proteins: Structure, Function and Genetics 73 2 (2008): 420-430. http://www.scopus.com/inward/record.url?eid=2-s2.0-52249108453&partnerID=MN8TOARS.
    10.1002/prot.22059
  71. Jenssen, H.; Sandvik, K.; Andersen, J.H.; Hancock, R.E.W.; Gutteberg, T.J.. "Inhibition of HSV cell-to-cell spread by lactoferrin and lactoferricin". Antiviral Research 79 3 (2008): 192-198. http://www.scopus.com/inward/record.url?eid=2-s2.0-47049097272&partnerID=MN8TOARS.
    10.1016/j.antiviral.2008.03.004
  72. Hamill, P.; Brown, K.; Jenssen, H.; Hancock, R.E.. "Novel anti-infectives: is host defence the answer?". Current Opinion in Biotechnology 19 6 (2008): 628-636. http://www.scopus.com/inward/record.url?eid=2-s2.0-57049083960&partnerID=MN8TOARS.
    10.1016/j.copbio.2008.10.006
  73. Jenssen, H.; Hilpert, K.; Hancock, R.E.W.. "Antibacterial host defence peptides of bovine origin". Chimica Oggi 25 3 SUPPL. (2007): 17-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547178884&partnerID=MN8TOARS.
  74. Jenssen, H.; Lejon, T.; Hilpert, K.; Fjell, C.D.; Cherkasov, A.; Hancock, R.E.W.. "Evaluating different descriptors for model design of antimicrobial peptides with enhanced activity toward P. aeruginosa". Chemical Biology and Drug Design 70 2 (2007): 134-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547803690&partnerID=MN8TOARS.
    10.1111/j.1747-0285.2007.00543.x
  75. Mistry, N.; Drobni, P.; Näslund, J.; Sunkari, V.G.; Jenssen, H.; Evander, M.. "The anti-papillomavirus activity of human and bovine lactoferricin". Antiviral Research 75 3 (2007): 258-265. http://www.scopus.com/inward/record.url?eid=2-s2.0-34250211795&partnerID=MN8TOARS.
    10.1016/j.antiviral.2007.03.012
  76. Jenssen, H.; Hamill, P.; Hancock, R.E.W.. "Peptide antimicrobial agents". Clinical Microbiology Reviews 19 3 (2006): 491-511. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746532309&partnerID=MN8TOARS.
    10.1128/CMR.00056-05
  77. Jenssen, H.; Gutteberg, T.J.; Rekdal, O.; Lejon, T.. "Prediction of activity, synthesis and biological testing of anti-HSV active peptides". Chemical Biology and Drug Design 68 1 (2006): 58-66. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747714647&partnerID=MN8TOARS.
    10.1111/j.1747-0285.2006.00412.x
  78. Jenssen, H.. "Anti herpes simplex virus activity of lactoferrin/lactoferricin - An example of antiviral activity of antimicrobial protein/peptide". Cellular and Molecular Life Sciences 62 24 (2005): 3002-3013. http://www.scopus.com/inward/record.url?eid=2-s2.0-29344463703&partnerID=MN8TOARS.
    10.1007/s00018-005-5228-7
  79. Jenssen, H.; Gutteberg, T.J.; Lejon, T.. "Modelling the anti-herpes simplex virus activity of small cationic peptides using amino acid descriptors". Journal of Peptide Research 66 SUPPL. 1 (2005): 48-56. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645063190&partnerID=MN8TOARS.
    10.1111/j.1747-0285.2006.00332.x
  80. Jenssen, H.; Gutteberg, T.J.; Lejon, T.. "Modelling of anti-HSV activity of lactoferricin analogues using amino acid descriptors". Journal of Peptide Science 11 2 (2005): 97-103. http://www.scopus.com/inward/record.url?eid=2-s2.0-14044258661&partnerID=MN8TOARS.
    10.1002/psc.604
  81. Samuelsen, Ø.; Haukland, H.H.; Jenssen, H.; Krämer, M.; Sandvik, K.; Ulvatne, H.; Vorland, L.H.. "Erratum: Induced resistance to the antimicrobial peptide lactoferricin B in Staphylococcus aureus (FEBS Letters (2005) 579 (3421-3426) DOI: 10.1016/j.febslet.2005.05.017)". FEBS Letters 579 24 (2005): 5437-5437. http://www.scopus.com/inward/record.url?eid=2-s2.0-25844433878&partnerID=MN8TOARS.
    10.1016/j.febslet.2005.09.001
  82. Hunter, H.N.; Ross Demcoe, A.; Jenssen, H.; Gutteberg, T.J.; Vogel, H.J.. "Human lactoferricin is partially folded in aqueous solution and is better stabilized in a membrane mimetic solvent". Antimicrobial Agents and Chemotherapy 49 8 (2005): 3387-3395. http://www.scopus.com/inward/record.url?eid=2-s2.0-23044463641&partnerID=MN8TOARS.
    10.1128/AAC.49.8.3387-3395.2005
  83. Jenssen, H.; Andersen, J.H.; Mantzilas, D.; Gutteberg, T.J.. "A wide range of medium-sized, highly cationic, a-helical peptides show antiviral activity against herpes simplex virus". Antiviral Research 64 2 (2004): 119-126. http://www.scopus.com/inward/record.url?eid=2-s2.0-7444233604&partnerID=MN8TOARS.
    10.1016/j.antiviral.2004.08.003
  84. Jenssen, H.; Andersen, J.H.; Uhlin-Hansen, L.; Gutteberg, T.J.; Rekdal, O.. "Anti-HSV activity of lactoferricin analogues is only partly related to their affinity for heparan sulfate". Antiviral Research 61 2 (2004): 101-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344304749&partnerID=MN8TOARS.
    10.1016/j.antiviral.2003.09.001
  85. Andersen, J.H.; Jenssen, H.; Sandvik, K.; Gutteberg, T.J.. "Anti-HSV activity of lactoferrin and lactoferricin is dependent on the presence of heparan sulphate at the cell surface". Journal of Medical Virology 74 2 (2004): 262-271. http://www.scopus.com/inward/record.url?eid=2-s2.0-4344615913&partnerID=MN8TOARS.
    10.1002/jmv.20171
  86. Andersen, J.H.; Jenssen, H.; Gutteberg, T.J.. "Lactoferrin and lactoferricin inhibit Herpes simplex 1 and 2 infection and exhibit synergy when combined with acyclovir". Antiviral Research 58 3 (2003): 209-215. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037721339&partnerID=MN8TOARS.
    10.1016/S0166-3542(02)00214-0
Activities

Event organisation

Event name
Type of event (Role)
Institution / Organization
2019 - 2019 2nd Wound healing workshop (2019 - 2019)
Workshop (Co-organisor)
University of Roskilde, Denmark
2018 - 2018 DanScatt Annual meeting, Roskilde (2018) (2018 - 2018)
Meeting (President of the Organising Committee)
University of Roskilde, Denmark
2017 - 2017 7th International Meeting on Antimicrobial Peptides, Copenhagen (2017) (2017 - 2017)
Meeting (President of the Organising Committee)
University of Roskilde, Denmark

Event participation

Activity description
Type of event
Event name
Institution / Organization
2018 - 2018 University of Stavanger, Norway, 2018
Seminar
University of Stavanger, Norway, 2018
University of Roskilde, Denmark
2018 - 2018 University of Oslo, Norway, 2018
Seminar
University of Oslo, Norway, 2018
University of Roskilde, Denmark
2017 - 2017 Nordic workshop on scattering from soft and biological matter, Oslo, 2017
Workshop
Nordic workshop on scattering from soft and biological matter, Oslo, 2017
University of Roskilde, Denmark
2017 - 2017 10th Peptoid Summit, Berkley, USA, 2017
Congress
10th Peptoid Summit, Berkley, USA, 2017
University of Roskilde, Denmark
2016 - 2016 26th European society of clinical microbiology and infectious diseases, Amsterdam, 2016
Congress
26th European society of clinical microbiology and infectious diseases, Amsterdam, 2016
University of Roskilde, Denmark
2016 - 2016 Norges Arktiske Universitet, Tromsø Norway, 2016
Conference
Norges Arktiske Universitet, Tromsø Norway, 2016
University of Roskilde, Denmark
2015 - 2015 5rd International Meeting on Antimicrobial Peptides, London, 2015
Meeting
5rd International Meeting on Antimicrobial Peptides, London, 2015
University of Roskilde, Denmark
2014 - 2014 University of Bergen, Norway, 2014
Conference
University of Bergen, Norway, 2014
University of Roskilde, Denmark
2014 - 2014 Aalborg University, Denmark, 2014
Conference
Aalborg University, Denmark, 2014
University of Roskilde, Denmark
2013 - 2013 3rd International Meeting on Antimicrobial Peptides, London, 2013 (opening lecture)
Meeting
University of Roskilde, Denmark
2013 - 2013 Texas A&M University, College Station, 2013
Seminar
Texas A&M University, College Station, 2013
University of Roskilde, Denmark
2008 - 2008 30th European Peptide Symposium, Helsinki, 2008
Symposium
University of Roskilde, Denmark
2008 - 2008 University of Gothenburg, Gothenburg, 2008
Conference
University of Gothenburg, Gothenburg, 2008
University of Roskilde, Denmark
2008 - 2008 Roskilde University, Roskilde, 2008
Congress
Roskilde University, Roskilde, 2008
Roskilde Universitet, Denmark

Association member

Society Organization name Role
2009 - Current International research projects in England, Germany, Portugal, Singapore, Norway, Ireland, and Italy, and with several Universities in Sweden, Canada and USA. Project coordination

Committee member

Activity description
Role
Institution / Organization
2016 - 2016 Management committee member in COST action CA15114; Anti-MIcrobial Coating Innovations to prevent infectious diseases (AMiCI)
Member
University of Roskilde, Denmark
2005 - 2009 Genom Canada and Gates Grand Challenges projects
Coordinator
University of Roskilde, Denmark
2000 - 2002 An antimicrobial drug development project between Alpharma, University of Tromsø and University hospital North-Norway
Coordinator
University of Roskilde, Denmark

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2013 - 2018 Biological Chemistry (biochemistry course) University of Roskilde, Denmark
2010 - 2018 Host defence peptides (protein chemistry & drug development), course coordinator and teacher Host defence peptides (protein chemistry & drug development) University of Roskilde, Denmark
2010 - 2018 Experimental biotechnology; course coordinator and teacher Experimental biotechnology; course coordinator and teacher University of Roskilde, Denmark
2009 - 2018 Microbiology University of Roskilde, Denmark
2009 - 2015 Biochemistry (part 2) University of Roskilde, Denmark
2009 - 2015 Bioinformatics University of Roskilde, Denmark
2009 - 2013 Molecules of life (biochemistry course) University of Roskilde, Denmark
Distinctions

Other distinction

2010 Patent WO 2010/139048 A1; Human milk peptides. Friel K.J. et al. 12/09/2010
2009 PTC/US14/52993 - UBC invention disclosure and assignment, titled; “Anti-biofilm peptides”