Curriculum Vitae
Helena Sofia de Azevedo Domingues
Identification
Personal identification
- Full name
- Helena Sofia de Azevedo Domingues
Citation names
- Domingues, Helena S.
- Domingues, Sofia A.
Author identifiers
- Ciência ID
- 1D14-1122-F41A
- ORCID iD
- 0000-0003-1230-2682
- Scopus Author Id
- 26635073600
Email addresses
- sofiadomingues@med.uminho.pt (Professional)
Addresses
- Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus de Gualtar, 4710-057, Braga, Braga, Portugal (Professional)
Websites
- https://www.linkedin.com/in/sofia-domingues-412a9424/ (Social media)
- https://www.researchgate.net/profile/Helena_Domingues (Scholar)
- https://www.mendeley.com/profiles/helena-sofia-domingues2/ (Scholar)
- https://www.scopus.com/authid/detail.uri?authorId=26635073600 (Scholar)
- https://www.news.inl.int/blog/celebrating-women-in-science-interview-with-sofia-domingues (Social media)
- https://loop.frontiersin.org/people/106050/overview (Scholar)
- https://jcs.biologists.org/content/133/15/jcs251934 (Professional)
Knowledge fields
- Medical and Health Sciences - Basic Medicine - Neurosciences
- Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
- Medical and Health Sciences - Basic Medicine - Neurosciences
- Medical and Health Sciences - Basic Medicine - Neurosciences
- Medical and Health Sciences - Basic Medicine - Immunology
- Medical and Health Sciences - Basic Medicine - Human Genetics
Languages
| Language | Speaking | Reading | Writing | Listening | Peer-review |
|---|---|---|---|---|---|
| English | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | |
| German | Elementary (A2) | Elementary (A2) | Elementary (A2) | Elementary (A2) | |
| French | Elementary (A2) | Elementary (A2) | Elementary (A2) | Elementary (A2) | |
| Spanish; Castilian | Elementary (A2) | Elementary (A2) | Elementary (A2) | Elementary (A2) |
Education
| Degree | Classification | |
|---|---|---|
|
2005/10/01 - 2010/09/27
Concluded
|
Biologia Celular (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Role of Th1 and Th17 CD4+ T cell subsets in the pathogenesis of Experimental Autoimmune Encephalomyelitis" (THESIS/DISSERTATION)
|
Aprovado com Distinção e Louvor |
|
2003/07/22
Concluded
|
Licenciatura em Bioquimica - Especialização em Bioquímica Aplicada (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Molecular Diagnosis of Helicobacter pylori from gastric biopsies by Real-time PCR" (THESIS/DISSERTATION)
|
15 valores |
|
1998
Concluded
|
Agrupamento Cientifico-Natural (Ensino secundário)
Escola Secundária de Amares, Portugal
"n/a" (THESIS/DISSERTATION)
|
18 valores |
Affiliation
Science
| Category Host institution |
Employer | |
|---|---|---|
| 2019/09/15 - Current | Contracted Researcher (Research) | Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal |
| Laboratório Associado ICVS 3B's, Portugal | ||
| 2019/09/15 - 2020/06/30 | Visiting Researcher (Research) | International Iberian Nanotechnology Laboratory, Portugal |
| 2017/01/01 - 2019/09/15 | Postdoc (Research) | International Iberian Nanotechnology Laboratory, Portugal |
| 2013/09/01 - 2016/12/31 | Postdoc (Research) | Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal |
| 2011/04/01 - 2013/08/31 | Auxiliary Researcher (Research) | Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal |
| 2009/09/01 - 2010/09/30 | Researcher (Research) | Max-Planck-Institut für Neurobiologie, Germany |
| 2006/08 - 2009/08 | Visiting Researcher (Research) | Max-Planck-Institut für Neurobiologie, Germany |
| 2003/11 - 2005/09 | Researcher (Research) | Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal |
| 2001 - 2003 | Research Trainee (Research) | Centro Hospitalar do Porto, Portugal |
Projects
Grant
| Designation | Funders | |
|---|---|---|
| 2020/01 - Current | SynChronize – Focused Ultrasound combined with Stem Cells Secretome and Pharmacotherapies: establishing a Multimodal path
for Parkinson’s Disease repair
MB28/2019
Researcher
|
Mantero Belard Prize for Neurodegenerative Diseases - Santa Casa da Misericórdia de Lisboa (SCML) |
| 2018/07 - 2021/06 | Uncovering the mechanistic assembly and function of actin ring networks in axonal biology and pathology.
PTDC/MED-NEU/28623/2017
Post-doc
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
Fundação para a Ciência e a Tecnologia, I.P.
Ongoing
|
| 2018/07 - 2021/06 | Combining Mesenchymal Stem Cells (MSCs) Secretome and Pharmacotherapies for the treatment of Parkinson’s Disease
POCI-01-0145-FEDER-029751
Integration into Research Grant Fellow
|
Fundação para a Ciência e a Tecnologia |
Contract
| Designation | Funders | |
|---|---|---|
| 2012/05 - 2015/04 | The oligodendrocyte “protrusiosome”: identification and characterization of proteins promoting oligodendrocyte differentiation
and myelination of axons.
Post-doc Fellow
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
|
| 2011/04 - 2013/08 | Study of proteins involved in oligodendrocyte process extension that regulate axon-glia interactions
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
European Commission
Concluded
|
| 2007/05 - 2010/09 | Microglial and Neuronal Changes in the Hippocampus Induced by Methamphetamine: Role of Pro-inflammatory Cytokines and Neuropeptide
Y
PhD Student Fellow
|
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
|
| 2007/05 - 2010/04 | Subventricular zone stem cells as a tool for brain repair in temporal lobe epilepsy
PhD Student Fellow
|
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
|
Outputs
Publications
| Journal article |
|
| Working paper |
|
Other
| Other output |
|
Activities
Oral presentation
| Presentation title | Event name Host (Event location) |
|
|---|---|---|
| 2019/07/10 | Mechanical plasticity in developing oligodendrocytes | XIV European Meeting on Glial Cells in Health and Disease
(Portugal, Portugal)
|
| 2016/11 | Development of an automated high-throughput image analysis method for oligodendrocyte morphological studies | i3S Annual Meeting
i3S (Póvoa do Varzim, Portugal)
|
| 2013/05/30 | The “Processossome”: identification and characterization of proteins promoting oligodendrocyte process outgrowth and (re)myelination | XIV Meeting of the Portuguese Society for Neurosciences (SPN)
(Luso, Portugal)
|
| 2011/04/16 | Esclerose Múltipla | III Jornadas de Neurofisiologia
Instituto Superior de Tecnologia e Saúde do Porto (ESTSP.IPP) (Porto, Portugal)
|
| 2009/09/14 | Th1 but not Th17 CD4+ T cells kill astrocytes that present myelin autoantigen | 2nd European Congress of Immunology
(Berlin)
|
Supervision
| Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
|---|---|---|
| 2015/10 - Current | Mechanical principles driving microglia activation
Co-supervisor
|
Biologia Celular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
| 2014/09 - 2015/10 | The oligodendrocyte “processosome”: novel regulators of differentiation and myelination
Supervisor
|
Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Faculdade de Ciências, Portugal |
| 2014/11 - 2015/09 | Effect of immobilized a6ß1 synthetic ligands on the behavior of oligodendrocyte progenitor cells (OPCs) cultured in 3D fibrin
hydrogels
Co-supervisor
|
Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
Event organisation
| Event name Type of event (Role) |
Institution / Organization | |
|---|---|---|
| 2016/10/20 - 2016/10/21 | "Careers in Science and beyond" was a 2-day workshop at the i3S - Instituto de Investigação e Inovação em Saúde, dedicated
to career development for young scientists and graduate students, particularly those in the Biological and Medical Sciences.
The workshop aimed to provide essential information and ideas to broaden young scientists' perception of possible career possibilities,
and help develop basic skills and competences needed for successfully entering and thriving in future careers.
(2015/10 - 2016/10)
Workshop (Member of the Organising Committee)
|
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal |
Event participation
| Activity description Type of event |
Event name Institution / Organization |
|
|---|---|---|
| 2017 - Current | Volunteer at INL "Mission NERD - Nanotechnology Education and Research Demonstrations". Mission NERD is a Science Outreach
activity from the International Iberian Nanotechnology Laboratory (INL). In an humanized perspective, it aims to take science
to patients in hospitals through practical demonstration of scientific concepts so the public understands the impact of nanoscience
and nanotechnology research in every daily human lives.
Other
|
Mission NERD - Science Outreach
International Iberian Nanotechnology Laboratory, Portugal
|
| 2019/07/10 - 2019/07/13 | Symposium organizer and speaker at the " 2019 XIV European Meeting on Glial Cells in Health and Disease", Porto (Portugal)
as a (http://glia2019.eu)
Congress
|
XIV European Meeting on Glial Cells in Health and Disease |
| 2018/12/08 - 2018/12/12 | Attended the meeting organized by the American Society for Cell Biology and the European Molecular Biology Organization (ASCB
| EMBO 2018 Meeting) in San Diego (USA) and presented my experimental work with a poster (https://ascb-embo2018.ascb.org)
Congress
|
ASCB | EMBO 2018 Meeting |
| 2018/04/22 - 2018/04/24 | Attended the European First Aid Course (14 hours), organized by the Portuguese Red Cross, Braga, Portugal
Workshop
|
European First Aid Course
Cruz Vermelha Portuguesa, Portugal
|
| 2017/09/18 - 2017/09/22 | Attended the 43th International Conference on Micro and Nanoengineering
Conference
|
43th International Conference on Micro and Nanoengineering
International Iberian Nanotechnology Laboratory, Portugal
|
| 2017/07/08 - 2017/07/11 | Attended and presented a poster at the meeting " 2017 XIII European Meeting on Glial Cells in Health and Disease" in Edinburgh
(UK) (http://www.glia2017.eu)
Congress
|
XIII European Meeting on Glial Cells in Health and Disease |
| 2016/12/02 - 2016/12/03 | Attended the "Science Communication Course", organized by the International Iberian Nanotechnology Laboratory. This series of workshops brings together creatives, social media experts, scientists and journalists, as well as other communication professionals, to empower you with new tools and discuss new challenges and innovative ways to involve people. | Science Communication Course
International Iberian Nanotechnology Laboratory, Portugal
|
| 2011 - 2016 | Science Ambassador at IBMC. Science dissemination activities and seminars to basic and high schools. The goal is to explain
students from 12 to 18 years old the fields of science we study, our latest findings, our daily life at the lab an the reasons
it took us to choose our scientist job (https://ibmcinebescolas.wordpress.com/embaixadores/)
Other
|
IBMC Science Ambassador - Science Outreach
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
| 2015/07/15 - 2015/07/18 | Attended the meeting "2015 XII European Meeting on Glial Cells in Health and Disease" in Bilbao , and presented my work with
a poster (http://bilbao2015.gliameeting.eu)
Conference
|
XII European Meeting on Glial Cells in Health and Disease |
| 2013/09/24 - 2013/09/28 | Attended and presented a poster in the School organized by the International Society for Neuroscience (ISN) in cooperation
with the Federation of European Neuroscience Societies (FENS) on "Local protein synthesis in axons and dendrites", held in
Crete in September 2013 (https://www.fens.org/News-Activities/News/2013/03/ISN-School-in-cooperation-with-FENS/?p=1)
Meeting
|
Local protein synthesis in axons and dendrites |
| 2012/06/26 - 2012/06/29 | Attended the course "Rho GTPases and cell signalling"
Symposium
|
Rho GTPases and cell signalling
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
| 2011/10/17 - 2011/10/21 | Attended the course "Transmission Electron Microscopy: Theory, Techniques and Applications", organized by IBMC, Porto, Portugal
Workshop
|
Transmission Electron Microscopy: Theory, Techniques and Applications
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
| 2011/08/24 - 2011/08/28 | Attended and presented a poster in the "10th Biennial International Society for Neurochemistry (ISN) Satellite Meeting on Myelin Biology" in Crete, Greece. | 10th Biennial ISN Satellite Meeting on Myelin Biology |
| 2011/05/23 - 2011/06/01 | Attended the course "Optical Microscopy Imaging for Biosciences", organized by IBMC, Porto, Portugal
Workshop
|
Optical Microscopy Imaging for Biosciences
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
| 2011/05/03 - 2011/05/13 | Attended the Course “Laboratory Animal Science” (80 hours), category C, accredited by the European Federation for Laboratory
Animal Science Associations (FELASA)”, organized by IBMC, Porto, Portugal.
Workshop
|
Laboratory Animal Science
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
| 2011/04/28 - 2011/04/30 | Attended and presented a poster in the 5th National Meeting on Cell Signalling (SINAL 2011 meeting) in Coimbra, Portugal | SINAL 2011 meeting |
| 2010/10/18 - 2010/10/22 | Attended the Workshop “Animal models in Neuroscience”, organized by the Harvard Medical School Portugal, IBMC, Porto, Portugal.
Workshop
|
Animal models in Neuroscience
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
| 2009/01/13 - 2009/01/13 | Attended the Workshop “Presenting Professionally”, organized by the International Communication Consultancy and the Max-Planck
Institute of Neurobiology, Martinsried, Germany
Workshop
|
Presenting Professionally
Max-Planck-Institut für Neurobiologie, Germany
|
| 2008/10/26 - 2008/10/30 | Attended and presented a poster in the "9th International Congress of Neuroimmunology" in Forth Worth, Texas, USA, organized
the the International Society of Neuroimmunology (ISNI)
Congress
|
9th International Congress of Neuroimmunology |
| 2007/11/14 - 2007/11/16 | Attended and presented a poster in the "XXXIII Reuniao Anual da Sociedade Portuguesa de Imunologia", at Instituto de Medicina
Molecular (iMM), Lisbon, Portugal
Meeting
|
XXXIII Reuniao Anual da Sociedade Portuguesa de Imunologia |
| 2006/10/11 - 2006/10/13 | Attended the International advanced course: “Inflammatory Type of Diseases: a Role for Cytokines”, organized by the International
Program of Post-Graduation of the Health Sciences School, University of Minho, Braga, Portugal.
Symposium
|
Inflammatory Type of Diseases: a Role for Cytokines
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
|
| 2006/04/17 - 2006/04/21 | Attended the Advanced course on Functional Genomics: “Laser-capture micro-dissection and real-time PCR analysis in biomedical sciences", organized by the Histocompatibility Centre of Coimbra, Portugal. | Laser-capture micro-dissection and real-time PCR analysis in biomedical sciences
Hospitais da Universidade de Coimbra, Portugal
|
| 2005/10/01 - 2006/04/15 | Attended 16 advanced courses (full-time) within the framework of the International Doctoral Program in Experimental Biology
and Biomedicine (PDBEB), organized by Centre for Neurosciences of Coimbra (CNC), Coimbra, Portugal.
Other
|
4th International Doctoral Program in Experimental Biology and Biomedicine (PDBEB)
Universidade de Coimbra, Portugal
|
| 2006/01/31 - 2006/02/02 | Attended the International advanced course: “Nervous system and Immune System: a Struggle and a Dialogue”, organized by the
International Program of Post-Graduation of the Health Sciences School, University of Minho, Braga, Portugal.
Symposium
|
Nervous system and Immune System: a Struggle and a Dialogue
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
|
| 2004/09/13 - 2004/09/17 | Attended the Advanced course: “Biostatistics in Health Sciences”, organized by the International Program of Post-Graduation
of the Health Sciences School, University of Minho, Braga, Portugal.
Symposium
|
Biostatistics in Health Sciences
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
|
| 2004/05/24 - 2004/05/27 | Attended the Advanced course: “Microarrays: principles and applications in medicine”, organized by the International Program
of Post-Graduation of the Health Sciences School, University of Minho, Braga, Portugal.
Symposium
|
Microarrays: principles and applications in medicine
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
|
| 2002/02 - 2002/07 | First Aid Course (70 hours) , Portuguese Red Cross, Amares, Portugal | First Aid Course
Cruz Vermelha Portuguesa, Portugal
|
| 2000/05/17 - 2000/05/19 | Attended the Forensics course for university students, organized by the Portuguese Forensics Society, Porto, Portugal.
Workshop
|
Forensics course for university students
Associação Portuguesa de Ciências Forenses, Portugal
|
Jury of academic degree
| Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
|---|---|---|
| 2017/10 | Aptamer functionalized DNA nanostructure for neuronal targeting and TrkB receptor activation
(Thesis) Main arguer
|
Ana Sofia Gonçalves Martins (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
| 2017/10 | Characterization of Cortico-Striatal Myelination in the Context of Pathological Repetitive Behaviors
(Thesis) Main arguer
|
Eliana Lopes Rio da Silva Lousada (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Faculdade de Engenharia, Portugal |
| 2016/01 | The role of astrocytes in the establishment and development of the experimental autoimmune encephalomyelitis (EAE) mice model
(Thesis) Main arguer
|
Marco António Gil Fernandes (Other)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
|
Association member
| Society Organization name | Role | |
|---|---|---|
| 2018/01/01 - Current | American Society for Cell Biology (ASCB) | |
| 2016 - Current | Portuguese Glial Network | Member |
| 2011 - Current | Sociedade Portuguesa de Neurosciências (SPN) |
Conference scientific committee
| Conference name | Conference host | |
|---|---|---|
| 2018/12/08 - Current | ASCB-EMBO 2018 meeting | San Diego, USA |
Course / Discipline taught
| Academic session | Degree Subject (Type) | Institution / Organization | |
|---|---|---|---|
| 2015/09/28 - 2015/09/28 | Células da Glia do Sistema Nervoso Central | Ensino de Biologia e Geologia no 3.º ciclo do Ensino Básico e no Ensino Secundário (Mestrado integrado) | Universidade do Porto Faculdade de Ciências, Portugal |
| 2015/07/01 - 2015/07/01 | De(re)myelination in the CNS | Programa Doutoral GABBA (Doutoramento) |
Interview (newspaper / magazine)
| Activity description | Newspaper / Forum | |
|---|---|---|
| 2020/08/12 | First Person section from the Journal of Cell Science - Company of Biologists is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. | Journal of Cell Science - Company of Biologists |
| 2020/02/19 | Celebration of the International Day of Women and Girls in Science and the International Women’s Day | INL communication office - https://www.news.inl.int/blog/celebrating-women-in-science-interview-with-sofia-domingues |
Journal scientific committee
| Journal title (ISSN) | Publisher | |
|---|---|---|
| 2020/08 - Current | Communications Biology - Nature Research (ISSN 2399-3642) | Nature |
| 2020/06 - Current | Frontiers in Psychiatry (1664-0640) | Frontiers |
| 2019/12 - Current | Nature Cell Death and Disease | Springer Nature |
| 2019/01 - Current | Journal of Neuroscience Methods (0165-0270) | Elsevier |
| 2018/03 - Current | Annals of Multiple Sclerosis and Related Disorders | |
| 2017/01 - Current | Frontiers in Cellular Neuroscience (1662-5102) | Frontiers Media SA |
| 2011/12 - Current | PLoS ONE (1932-6203) | Public Library of Science |
Mentoring / Tutoring
| Topic | Student name | |
|---|---|---|
| 2018/10 - Current | PhD mentoring - Design of bone-stimulating implants by mechanotransduction modulation | Francisca Rocha Melo Fonseca |
| 2015/07/06 - 2015/07/10 | Ocupação Científica de Jovens nas Férias (OCJF) - 2015 - Ciência Viva | Ana Luisa Fonseca e Adriana Costa |
| 2014/06/30 - 2014/07/04 | Ocupação Científica Jovens em Férias (OCJF) - 2014 - Ciência Viva | Patricia Melo e Diana Esteves |
| 2012/07/01 - 2012/07/05 | Ocupação Cientifica Jovens em Férias (OCJF) - 2012 - Ciência Viva | Mariana Pereira e Francisco Almeida |
| 2011/09 - 2012/06 | PhD mentoring - In vivo evaluation of myelination alterations during hyperbilirubinemia | Andreia Barateiro |
Distinctions
Award
| 2018 | ASCB-EMBO Travel Award to the ASCB2018 meeting
European Molecular Biology Laboratory, Germany
|
| 2013 | FCT post-doctoral fellowship
Fundação para a Ciência e a Tecnologia, I.P., Portugal
|
| 2011 | FP7 Marie Curie Intra-European (IEF) Fellowships
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions, Belgium
|
| 2005 | FCT PhD fellowship
Fundação para a Ciência e a Tecnologia, I.P., Portugal
|
Other distinction
| 2020 | Selected cover of the issue August, 2020; 133 (15) from Journal of Cell Science from the Company of Biologists
Journal of Cell Science, United Kingdom
Company of Biologists Ltd, United Kingdom |