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Hugo Osorio graduated in Biochemistry (1999) and holds a PhD in Biomedical Sciences (2004) from the University of Porto. His research focuses on the development and application of mass-spectrometry based proteomics approaches in biomedicine with a focus on cancer proteomics and glycosylation profiling. Hugo Osorio is the Head of the i3S Proteomics Scientific Platform and Professor at University of Porto. He is member of the board of the Portuguese Proteomics Association – ProCura and manages the i3S node of the Portuguese Mass Spectrometry Network- RNEM integrated in the FCT Research Infrastructures RoadMap. He organizes and participates in pre and postgraduate mass spectrometry and proteomics courses. As of February 2025, Hugo Osorio has 101 publications in international peer-reviewed journals and three book chapters. His research work has over 3900 citations and with an h-index of 27 (Scopus).
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Identification

Personal identification

Full name
Hugo Alexandre Carvalho Pinheiro Osório

Citation names

  • Osorio, Hugo

Author identifiers

Ciência ID
211F-9A6D-2886
ORCID iD
0000-0002-6362-8255
Scopus Author Id
6601979151

Email addresses

  • hosorio@i3s.up.pt (Professional)

Addresses

  • i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135, Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Portuguese Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
French Intermediate (B1) Intermediate (B1) Intermediate (B1) Upper intermediate (B2)
Education
Degree Classification
2004/12/17
Concluded
 Biomedical Sciences (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Role of oxidative stress in Saccharomyces cerevisiae nucleotide metabolism" (THESIS/DISSERTATION)
 Aprovado por unanimidade
1999/12/17
Concluded
 Biochemistry (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"n/a" (THESIS/DISSERTATION)
 16
Affiliation

Science

Category
Host institution 		Employer
2015/10/01 - Current Researcher (Research) Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2006/10/01 - Current Researcher (Research) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2023/02/23 - 2023/07/31 Invited Assistant Professor (University Teacher) Universidade do Porto Faculdade de Ciências, Portugal
2015/04/07 - 2023/01/01 Invited Assistant Professor (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
Projects

Grant

Designation Funders
2022/01/01 - 2026/05/01 NEUROSENSE - NEUROendocrine SENSor for Sudden Unexpected Death in Epilepsy (SUDEP) prediction and prevention
101047131
Researcher
Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
 European Commission
Ongoing
2016/01 - 2018/12 CELLULAR GLYCOENGINEERING FOR EVALUATION OF POST-TRANSLATIONAL MODIFICATIONS OF RECEPTORS IN CANCER: THERAGNOSTIC APPLICATIONS
Provided by PTCRIS: 139174
 Fundação para a Ciência e a Tecnologia, I.P.

Contract

Designation Funders
2023/03/01 - 2026/02/28 Targeting a ‘toolbox’ of human microbiome O-Glycan-Selective proteins towards new approaches in cancer research
2022.06104.PTDC
10.54499/2022.06104.PTDC
Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2024/12/31 GLYCOTARGET. A NEW FRONTIER IN EXTRACELLULAR VESICLE-MEDIATED CANCER IMMUNOMODULATION
PTDC/MEC-ONC/0491/2021
Researcher
Fundação para a Ciência e a Tecnologia
2022/01/01 - 2024/12/31 COoperative Mechanical couPling of adherens junctions and focaL adhesIons supporting breast CancEr progression
PTDC/BIA-BFS/0812/2021
Researcher
Fundação para a Ciência e a Tecnologia
2022/01/01 - 2024/12/31 SweetKiller: Monosaccharide analogues as novel therapeutic agents to block glycan-driven cancer cell metastasis
PTDC/MED-QUI/2335/2021
Researcher
Fundação para a Ciência e a Tecnologia
2023/01/01 - 2024/06/30 Understand the contribution of Extracellular Vesicles for the establishment of a pancreatic cancer METastatic niche at the liver – the EVMet
2022.01036.PTDC
Researcher
Fundação para a Ciência e a Tecnologia
2022/01/01 - 2023/06/30 Exploring glycans as novel players in tumor-adipose tissue transdifferentiation and cancer cachexia
EXPL/MED-ONC/1001/2021
Researcher
Fundação para a Ciência e a Tecnologia
2022/01/01 - 2023/06/30 Glycan-defined organoids as gastric cancer avatars for patient stratification and prediction of therapeutic response
EXPL/BTM-ORG/1450/2021
Researcher
Fundação para a Ciência e a Tecnologia
2018/07/15 - 2022/01/15 Molecular strategies to be applied in the depuration of commercial bivalves for elimination of toxic compounds
PTDC/ASP-PES/31762/2017
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Instituto Português do Mar e da Atmosfera, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/15 - 2022/01/14 Predicting patients' response to liposomal anticancer drugs: focusing on LRP1B endocytic activity
PTDC/MEC-ONC/31520/2017
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/10/01 - 2021/09/30 Advances in MUC1 Glycan Cancer Antigens: From structure to function in the fight against cancer
PTDC/BIA-MIB/31028/2017
Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/10/01 - 2021/09/30 Occult Hepatitis C in Different Clinical Settings: Detection, Characterization and Diagnostic Tools
PTDC/SAU-SER/30788/2017
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

International Iberian Nanotechnology Laboratory, Portugal

Centro Hospitalar e Universitário de Coimbra EPE, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/01 - 2021/06/30 Circulating tumor Extracellular Vesicles for minimally-invasive detection of Minimal Residual Disease in Acute Myeloid Leukemia patients
PTDC/MEC-HEM/30457/2017
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal

Centro Hospitalar Universitário de São João, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/01 - 2021/06/30 Identification of Novel GlycoSpecific Drugs to Tackle Cancer Cell Metastasis
PTDC/MED-QUI/29780/2017
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/01 - 2021/06/30 Meet the ExoNet: Targeting the Exosomes Network in Pancreatic Cancer
PTDC/MEC-GAS/32189/2017
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/01 - 2021/06/30 Microbiome-derived metabolites as new gastric cancer biomarkers
PTDC/MED-OUT/32532/2017
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/01 - 2021/06/30 Stroke in translation: Biomarkers for diagnosis and management of acute ischemic stroke
PTDC/MEC-NEU/31674/2017
Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Centro Hospitalar Universitário do Porto EPE, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/01 - 2021/06/30 Thymus regeneration: Development of a high-content discovery program to identify new bioactive compounds and molecular determinants that induce Foxn1 expression in thymic epithelial cells.
PTDC/MED-IMU/29129/2017
Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2012/10/01 - 2015/12/31 Mucin MUC16 - CA125 cancer biomarker - biological functions and development of new biomarker assays
PTDC/SAU-ONC/117216/2010
117216
Provided by PTCRIS: 117216
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2012/03/01 - 2015/06/30 Unravelling a new Helicobacter pylori virulence factor involved in tight junction dysfunction
PTDC/BIA-MIC/116890/2010
Provided by PTCRIS: 116890
116890
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2011/01/01 - 2012/12/31 Projecto Estratégico - LA 3 - 2011-2012
PEst-C/SAU/LA0003/2011
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2009/01/01 - 2012/03/31 Early detection of cancer using serum biomarkers based on aberrant post-translational modifications of O-glycoproteins, O-PTM-Biomarkers.
PIC/IC/82716/2007
Provided by PTCRIS: 82716
82716
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2000/07/01 - 2004/06/30 METABOLISMO DE NUCLEÓTIDOS E DINUCLEÓSIDOS POLIFOSFATOS EM SITUAÇÕES DE STRESS OXIDATIVO.
SFRH/BD/1477/2000
Universidade do Porto Faculdade de Ciências, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Osório, Hugo; de Almeida, André M.; Campos, Alexandre. "Sample Preparation for 2DE Using Samples of Animal Origin". In Proteomics in Domestic Animals: from Farm to Systems Biology, 37-53. Springer International Publishing, 2018.
    10.1007/978-3-319-69682-9_4
  2. Rodrigues, Pedro M.; Schrama, Denise; Campos, Alexandre; Osório, Hugo; Freitas, Marisa. "Applications of Proteomics in Aquaculture". In Agricultural Proteomics Volume 1, 175-209. Springer International Publishing, 2016.
    10.1007/978-3-319-43275-5_10
  3. Osório, Hugo; Reis, Celso A.. "Mass Spectrometry Methods for Studying Glycosylation in Cancer". In Mass Spectrometry Data Analysis in Proteomics, 301-316. Humana Press, 2013.
    10.1007/978-1-62703-392-3_13
Conference abstract
  1. Felício, Daniela; Osorio, Hugo; Pereira, Maria da Conceição; Sequeiros, Jorge; Lemos, Carolina; Santos, Mariana. "The potential impact of TTBK2 missense variants in SCA11: in silico analysis and a phosphoproteome study". Paper presented in 56th European Society of Human Genetics (ESHG) Conference, Glasgow, 2024.
    Accepted
  2. Pereira, Clara; Pereira, Andreia; Pereira, Joana; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "Identification of the F1Fo ATP synthase complex ß Subunit as a potential target for the phosphatase Sit4p, impacting on mitochondrial function in yeast". Paper presented in 27th International Conference on Yeast Genetics and Molecular Biology, Yeast, Levico Terme (Trento), 2015.
    Published
Conference paper
  1. Pereira, Clara; Pereira, Andreia T.; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vitor. "The Sit4p phosphatase controls mitochondrial function and lifespan by regulating the phosphorylation of the ATP synthase beta subunit Atp2p". 2018.
    10.1016/j.freeradbiomed.2018.04.271
Conference poster
  1. Figueiredo, Gonçalo; Osorio, Hugo; Marta Mendes; Mendo, Sónia. "Complete genome of Pedobacter lusitanus NL19: a comprehensive genomic analysis". Paper presented in Microbiotec'23, 2023.
  2. Girão, Hugo; Macário-Monteiro, Joana; Ricardo Silva e Sousa; Ana C. Figueiredo; Elena Doria; Osorio, Hugo; Patrick Meraldi; Ekaterina L. Grishchuk; Maiato, Helder. Corresponding author: Maiato, Helder. "Kinetochores read detyrosinated tubulin to sustain microtubule attachments". Paper presented in 2023 ASCB Meeting - Boston, EUA, 2023.
  3. Diana Luísa Almeida-Nunes; Nunes M; Osorio, Hugo; Verónica Ferreira; Cláudia Lobo; Paula Monteiro; Miguel Henriques Abreu; et al. "Análise proteómica de ascites de pacientes com cancro do ovário reflete a modificação metabólica no microambiente tumoral durante a quimioterapia". Paper presented in 8º Curso Avançado de Ginecologia Oncológica, 2023.
  4. Ribeiro, Sónia; Pereira, Ana Rita S.; Rocha, Filipe; Vala, Inês Sofia; Pinto, Ana Teresa; Ministro, Augusto; Poli, Esmeralda; et al. Corresponding author: Santos, Susana Constantino Rosa. "Cardiac tissue remodelling induced by ionizing radiation in a dosedependent manner is an early predictor of subclinical cardiac dysfunction.". Paper presented in European Radiation Protection Week 2022, 2022.
  5. Brandão, Catarina; Nunes, Diana; Nunes, Mariana; Osório, Hugo; Ricardo, Sara. "Development of an In Silico Approach to Identify Key Proteins Involved in the Peritoneal Dissemination of Ovarian Cancer". Paper presented in VII Jornadas da Bioquímica, 2022.
  6. Ângela Marques-Magalhães; Marta Laranjeiro Pinto; Cruz, Tânia; Caldeira, Joana; Osorio, Hugo; Pedro Amoroso Canão; Elisabete Rios; et al. Corresponding author: Maria José Oliveira. "Unveil the biochemical and biomechanical properties of colorectal cancer patients-derived tissues from different colon locations". Paper presented in The Structural Microenvironment: Breaking down the walls of cancer (EACR), 2022.
  7. Marques, Sara; Osorio, Hugo; Salta, S; José Pedro Sequeira; Matas, Isabel María; Simão, Adélia ; Madaleno, João; Carvalho, Armando; Silva, Eliane. "Occult hepatitis C Infection: HCV/OCI Infection and Replication in MDBK and Huh7.5 cell line cultures.". Paper presented in 31st Annual Meeting of the Society for Virology., 2022.
  8. Ângela Marques-Magalhães; Marta Laranjeiro Pinto; Cruz, Tânia; Caldeira, Joana; Osorio, Hugo; Pedro Amoroso Canão; Elisabete Rios; et al. Corresponding author: Maria José Oliveira. "Dissecting the biochemical and biomechanical properties of colorectal cancer extracellular matrix". Paper presented in II ASPIC-ASEICA International meeting ¿ Current trends in precision medicine in cancer, 2021.
  9. Ângela Marques-Magalhães; Marta Laranjeiro Pinto; Cruz, Tânia; Caldeira, Joana; Osorio, Hugo; Pedro Amoroso Canão; Elisabete Rios; et al. Corresponding author: Maria José Oliveira. "Dissecting the properties of colorectal cancer patients-derived extracellular matrix". Paper presented in Goodbye Flat Biology: Next generation cancer models, 2021.
  10. Ângela Marques-Magalhães; Marta Laranjeiro Pinto; Cruz, Tânia; Caldeira, Joana; Osorio, Hugo; Pedro Amoroso Canão; Elisabete Rios; et al. Corresponding author: Maria José Oliveira. "Cancro colorrectal: propriedades bioquímicas e biomecânicas da matriz extracelular de pacientes". Paper presented in 3º Encontro Nacional de Jovens Investigadores em Oncologia (ENJIO), 2021.
  11. Patrícia C. Henriques; Osorio, Hugo; Fernão D. Magalhães; Gonçalves, Inês de Castro. "How graphene surface features impact plasma protein adsorption: the power of proteomics". Paper presented in 31st Conference of the European Society for Biomaterials (ESB), 2021.
  12. Malta, Mariana D.; Osorio, Hugo; Guttmann-Gruber, Christina; Kocher, Thomas; Carvalho, Andreia F.; Cerqueira, Mariana T.; Marques, Alexandra P.. "Extracellular Matrix Distinct Signature Among Dystrophic Epidermolysis Bullosa Variants". Paper presented in 1st Global Congress on Epidermolysis Bullosa, 2020.
    10.2340/00015555-3586
  13. Pereira. Clara; Martins, Telma; Pereira, Andreia T.; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "Phosphoproteomic screening identifies ATP synthase subunit beta as a target of the yeast type 2A-like protein phosphatase Sit4p". Paper presented in MitoPorto ¿ Advances in mitochondrial research, 2017.
  14. Pereira, Clara; Pereira, Andreia T.; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "Identification of the F1Fo ATP synthase ß subunit as a target of the phosphatase Sit4p, impacting mitochondrial function and longevity in yeast". Paper presented in XIX Congresso Nacional de Bioquímica, 2016.
  15. Pereira, Clara; Pereira, Andreia T.; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "Phosphoproteome analysis to elucidate the role of the ceramide-activated protein phosphatase Sit4p in mitochondrial function and lifespan in yeast". Paper presented in XVIII Congresso Nacional de Bioquímica, 2014.
  16. Pereira, Clara; Pereira, Andreia; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "Identification of the F1Fo ATP synthase complex ß subunit as a potential target for the phosphatase Sit4p, impacting lifespan extension in yeast". Paper presented in 18th European BioEnergetics Conference, 2014.
  17. Pereira, Clara; Pereira, Andreia T.; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "Using phosphoproteomics to elucidate the role of the phosphatase Sit4p in mitochondrial function and lifespan yeast". Paper presented in IJUP14-7º Encontro de Investigação Jovem da Universidade do Porto, 2014.
  18. Barbosa, António Daniel; Osório, Hugo; Alves, Mariana; Amorim, Maria Amélia; Moradas-Ferreira, Pedro; Costa, Vítor. "ISC1-dependent regulation of the cell integrity pathway is required for oxidative stress resistance and chronological lifespan in yeast". Paper presented in Annual meeting of the Coordination Action LINK-AGE - Third topic research groups meeting, 2009.
  19. Barbosa, António Daniel; Osório, Hugo; Alves, Mariana; Amorim, Maria Amélia; Moradas-Ferreira, Pedro; Costa, Vítor. "The role of Sit4 in Isc1-dependent sphingolipid signalling during oxidative stress and chronological ageing in yeast". Paper presented in 24th International Conference on Yeast Genetics and Molecular Biology, 2009.
  20. Barbosa, António Daniel; Osório, Hugo; Alves, Mariana; Amorim, Maria Amélia; Moradas-Ferreira, Pedro; Costa, Vítor. "Chronological ageing and oxidative stress in Saccharomyces cerevisiae: the role of Sit4 in Isc1-dependent sphingolipid signalling". Paper presented in MARK-AGE/LINK-AGE joint summer school "From molecular mechanisms to biomarkers of human ageing", 2009.
  21. Barbosa, António Daniel; Osório, Hugo; Alves, Mariana; Amorim, Maria Amélia; Moradas-Ferreira, Pedro; Costa, Vítor. "ISC1-dependent sphingolipid signalling during oxidative stress and chronological ageing in yeast". Paper presented in XVI Congresso Nacional de Bioquímica, 2008.
Journal article
  1. Silva, Catarina S.; Casanova, Marta R.; Ferreirinha, Pedro; da Silva Morais, Alain; Osório, Hugo; Lima, Ana C.; Fangueiro, Joana F.; et al. "The effect of conditioned medium from human amniotic membrane-derived mesenchymal stem cells on thymus involution". Life Sciences 362 (2025): 123366. https://doi.org/10.1016/j.lfs.2024.123366.
    10.1016/j.lfs.2024.123366
  2. Gonçalves, Bruna; Pires, Diana Priscila; Fernandes, Liliana; Pacheco, Miguel; Ferreira, Tiago; Osório, Hugo; Soares, Ana Raquel; Henriques, Mariana; Silva, Sónia. "Biofilm matrix regulation by Candida glabrata Zap1 under acidic conditions: transcriptomic and proteomic analyses". Microbiology Spectrum 12 12 (2024): https://doi.org/10.1128/spectrum.01201-24.
    10.1128/spectrum.01201-24
  3. Hugo Girão; Joana Macário-Monteiro; Ana C. Figueiredo; Ricardo Silva e Sousa; Elena Doria; Vladimir Demidov; Hugo Osório; et al. "a-tubulin detyrosination fine-tunes kinetochore-microtubule attachments". Nature Communications (2024): https://doi.org/10.1038/s41467-024-54155-8.
    10.1038/s41467-024-54155-8
  4. Chagas, Ana Carolina S.; Ribeiro, David M.; Osório, Hugo; Abreu, Ana A.P.; Okino, Cintia H.; Niciura, Simone C.M.; Amarante, Alessandro F.T.; et al. "Molecular signatures of Haemonchus contortus infection in sheep: A comparative serum proteomic study on susceptible and resistant sheep breeds". Veterinary Parasitology 331 (2024): 110280. https://doi.org/10.1016/j.vetpar.2024.110280.
    10.1016/j.vetpar.2024.110280
  5. Almeida-Nunes, Diana Luísa; Nunes, Mariana; Osório, Hugo; Ferreira, Verónica; Lobo, Cláudia; Monteiro, Paula; Abreu, Miguel Henriques; et al. "Ovarian cancer ascites proteomic profile reflects metabolic changes during disease progression". Biochemistry and Biophysics Reports 39 (2024): 101755. https://doi.org/10.1016/j.bbrep.2024.101755.
    10.1016/j.bbrep.2024.101755
  6. Francisca Diniz; Sofia Lamas; Hugo Osório; Paulo Aguiar; Daniela Freitas; Fátima Gärtner; Bruno Sarmento; Celso A. Reis; Joana Gomes. "Nanoparticles targeting Sialyl-Tn for efficient tyrosine kinase inhibitor delivery in gastric cancer". Acta Biomaterialia (2023): https://doi.org/10.1016/j.actbio.2023.08.014.
    10.1016/j.actbio.2023.08.014
  7. Joana Peixoto; Catarina Príncipe; Ana Pestana; Hugo Osório; Marta Teixeira Pinto; Hugo Prazeres; Paula Soares; Raquel T. Lima. "Using a Dual CRISPR/Cas9 Approach to Gain Insight into the Role of LRP1B in Glioblastoma". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms241411285.
    10.3390/ijms241411285
  8. Celina São José; Carla Pereira; Marta Ferreira; Ana André; Hugo Osório; Irene Gullo; Fátima Carneiro; Carla Oliveira. "3D Chromatin Architecture Re-Wiring at the CDH3/CDH1 Loci Contributes to E-Cadherin to P-Cadherin Expression Switch in Gastric Cancer". Biology (2023): https://doi.org/10.3390/biology12060803.
    10.3390/biology12060803
  9. Juliana Poças; Catarina Marques; Catarina Gomes; Andreia Hanada Otake; Filipe Pinto; Mariana Ferreira; Tiago Silva; et al. "Syndecan-4 is a maestro of gastric cancer cell invasion and communication that underscores poor survival". Proceedings of the National Academy of Sciences 120 (2023):
    Open access • 10.1073/pnas.2214853120
  10. Sofia Esteves; Clara Lima; Inês Costa; Hugo Osório; Carmen Fernandez-Becerra; Nuno Santarém; Anabela Cordeiro-da-Silva. "Characterization and Proteomic Analysis of Plasma EVs Recovered from Healthy and Diseased Dogs with Canine Leishmaniosis". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24065490.
    10.3390/ijms24065490
  11. Ana Teresa Pinto; Ana Beatriz Machado; Hugo Osório; Marta Laranjeiro Pinto; Rui Vitorino; Gonçalo Justino; Cátia Santa; et al. "Macrophage Resistance to Ionizing Radiation Exposure Is Accompanied by Decreased Cathepsin D and Increased Transferrin Receptor 1 Expression". Cancers (2022): https://doi.org/10.3390/cancers15010270.
    10.3390/cancers15010270
  12. Francisca Diniz; Maria Azevedo; Flávia Sousa; Hugo Osório; Diana Campos; Paula Sampaio; Joana Gomes; Bruno Sarmento; Celso A. Reis. "Polymeric nanoparticles targeting Sialyl-Tn in gastric cancer: A live tracking under flow conditions". Materials Today Bio 16 (2022): 100417-100417. http://dx.doi.org/10.1016/j.mtbio.2022.100417.
    10.1016/j.mtbio.2022.100417
  13. José C. Soares; Hugo Osório; Manuela Pintado; Marta W. Vasconcelos. "Effect of the Interaction between Elevated Carbon Dioxide and Iron Limitation on Proteomic Profiling of Soybean". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms232113632.
    10.3390/ijms232113632
  14. Maria João Leal Romeu; Dany Domínguez Pérez; Daniela Almeida; João Morais; Mário J. Araújo; Hugo Osório; Alexandre Campos; Vítor Vasconcelos; Filipe Mergulhão. "Hydrodynamic conditions affect the proteomic profile of marine biofilms formed by filamentous cyanobacterium". npj Biofilms and Microbiomes 8 1 (2022): http://dx.doi.org/10.1038/s41522-022-00340-w.
    10.1038/s41522-022-00340-w
  15. Diogo Coelho; David Ribeiro; Hugo Osório; André Martinho de Almeida; José António Mestre Prates. "Integrated Omics analysis of pig muscle metabolism under the effects of dietary Chlorella vulgaris and exogenous enzymes". Scientific Reports 12 1 (2022): http://dx.doi.org/10.1038/s41598-022-21466-z.
    10.1038/s41598-022-21466-z
  16. Sónia Ribeiro; Ana Rita Simões; Filipe Rocha; Inês Sofia Vala; Ana Teresa Pinto; Augusto Ministro; Esmeralda Poli; et al. "Molecular Changes In Cardiac Tissue As A New Marker To Predict Cardiac Dysfunction Induced By Radiotherapy". Frontiers in Oncology 12 (2022): http://dx.doi.org/10.3389/fonc.2022.945521.
    10.3389/fonc.2022.945521
  17. Ana M. Moreira; Rui M. Ferreira; Patrícia Carneiro; Joana Figueiredo; Hugo Osório; José Barbosa; John Preto; et al. "Proteomic Identification of a Gastric Tumor ECM Signature Associated With Cancer Progression". Frontiers in Molecular Biosciences 9 (2022): http://dx.doi.org/10.3389/fmolb.2022.818552.
    10.3389/fmolb.2022.818552
  18. David M. Ribeiro; Diogo Coelho; Hugo Osório; Cátia Martins; João P. Bengala Freire; João Almeida; Olga Moreira; André M. Almeida; José A.M. Prates. "Effect of dietary incorporation of Chlorella vulgaris and CAZyme supplementation on the hepatic proteome of finishing pigs". Journal of Proteomics 256 (2022): 104504-104504. http://dx.doi.org/10.1016/j.jprot.2022.104504.
    10.1016/j.jprot.2022.104504
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Intellectual property

Patent
  1. Gertrude Thompson; Silva, Eliane; Marques, Sara; Osorio, Hugo; Carvalheira, Julio Gil Vale. 2013. "HCV homolog fragments, cell-lines and applications thereof.". Portugal.
    Expired
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2019/10/01 - 2020/12/11 Multiple Testing in Proteomics
Co-supervisor
 Master in Bioinformatics & Computational Biology (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2009 - 2013 Discovery of Novel Biomarkers in Gastric Cancer based on Post-translational Modifications of Glycoproteins
Co-supervisor
Universidade do Porto Faculdade de Medicina, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2021/02/26 Molecular effects of metals and ionizing radiation on cells exposed in vitro to an effluent from a uranium mine
(Thesis) Main arguer
 Letícia Isabel Rato Vieira (Master)
Universidade de Aveiro, Portugal
2020/01/28 Deepening the study of the two-peptide lantibiotic lichenicidin: bioengineering, toxicity and mode of action.
Thesis Member
 Joana Cristina Pacheco Barbosa (PhD)
Universidade de Aveiro, Portugal
2015/10/16 A glycoproteomics discovery strategy for gastric cancer biomarkers
Thesis Member
 Diana Campos (PhD)
Universidade do Porto Faculdade de Medicina, Portugal

Association member

Society Organization name Role
2017/01/01 - Current Portuguese Mass Spectrometry Network i3S Node Director
2009/01/01 - Current Portuguese Proteomics Association - Procura Board Member