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Rafaela Ribeiro Agostinho. Completed the Mestrado in Oncobiologia - Mecanismos Moleculares do Cancro in 2020/03/17 by Universidade do Algarve and Licenciatura in Ciências Biomédicas in 2017 by Universidade do Algarve. Attends the Doutoramento in Ciências Biomédicas by Universidade do Algarve - Campus de Gambelas since 2021/12/01. Is Research Trainee in Universidade do Algarve - Campus de Gambelas. Published 1 articles in journals. Organized 5 event(s). Participated in 13 event(s). Co-supervised 2 work(s) of course completion of LSc/BSc. Has received 1 awards and/or honors. Participates and/or participated as Research Fellow in 2 project(s). Works in the area(s) of Medical and Health Sciences with emphasis on Basic Medicine with emphasis on Neurosciences, Natural sciences with emphasis on Biological Sciences with emphasis on Molecular Biology, Natural sciences with emphasis on Biological Sciences with emphasis on Cell Biology and Natural sciences with emphasis on Biological Sciences with emphasis on Developmental Biology. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Stem Cells; Organoids; gene editing; CRISPR-Cas system; human IPSCs cultures; zebrafish; mice; stem cell; therapy; technology; regeneration; human diseases; .
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Identification

Personal identification

Full name
Rafaela Ribeiro Agostinho

Citation names

  • Agostinho, Rafaela

Author identifiers

Ciência ID
231B-D283-9C07

Email addresses

  • rafaelaribeiroagostinho@gmail.com (Professional)

Telephones

Mobile phone
  • 962938313 (Personal)

Addresses

  • Rua Santa Casa da Misericórdia de Olhão, nº. 56, 4ºDrt, 8700-132, Olhão, Faro, Portugal (Personal)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Developmental Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Education
Degree Classification
2021/12/01 - 2025
Ongoing
 Ciências Biomédicas (Doutoramento)
Universidade do Algarve - Campus de Gambelas, Portugal
2020/11 - 2021
Concluded
 Abordagens Experimentais em Biomedicina (Pós-Graduação)
Universidade do Algarve, Portugal
2018/09 - 2020/03/17
Concluded
 Oncobiologia - Mecanismos Moleculares do Cancro (Mestrado)
Universidade do Algarve, Portugal
"Papel da acetilação N-terminal na fertilidade e no envelhecimento" (THESIS/DISSERTATION)
 17
2014 - 2017
Concluded
 Ciências Biomédicas (Licenciatura)
Universidade do Algarve, Portugal
"Efeito da inibição da sinalização BMP na segmentação embrionária" (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2021/12/01 - Current Research Trainee (Research) Universidade do Algarve - Campus de Gambelas, Portugal
2020/11/16 - 2021/11/15 Contracted Researcher (Research) Universidade do Algarve, Portugal
Universidade do Algarve Centro de Investigação em Biomedicina, Portugal
2018/07 - 2020/03 Research Trainee (Research) Universidade do Algarve, Portugal
Universidade do Algarve Centro de Investigação em Biomedicina, Portugal
2017/01 - 2017/06 Research Trainee (Research) Universidade do Algarve, Portugal
Universidade do Algarve Centro de Investigação em Biomedicina, Portugal
Projects

Contract

Designation Funders
2022 - 2023 Identification of S-sulfhydration targets in Down Syndrome: the role of gasotransmitter hydrogen sulfide (H2S) signaling in neurodevelopment
EXPL/MED-NEU/1240/2021
Research Fellow
Universidade do Algarve - Campus de Gambelas, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
2020/11/16 - 2021 GT-LightUP - Signaling Gasotransmitters Light Up
PTDC/QUI-QFI/29319/2017
Research Fellow
Universidade do Algarve, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
Ongoing
Outputs

Publications

Conference poster
  1. Agostinho, Rafaela; Marques, Vera Lúcia Maia; Sofia M. Calado; Bragança, José; Nzwalo, Hipólito; Mónica Bota; Raquel Melo Medeiros; et al. "Dysregulation of H2S levels in a cellular model of Down Syndrome". Paper presented in IX Clinical Biochemistry Workshop, 2024.
  2. Agostinho, Rafaela; Vera Marques; Sofia M. Calado; Tomás Azevedo; José Bragança; Nzwalo, Hipólito; Simão, Sónia; Araújo, Inês Maria. "Assessment of H2S production in fibroblasts by time-lapse fluorescence imaging prior to establishment of fibroblast-derived iPS cell lines". Paper presented in Spanish & Portuguese Advanced Optical Microscopy (SPAOM) 2023, 2023.
  3. Vera Marques; Agostinho, Rafaela; Tomás Azevedo ; Simão S.; Inês Araújo. "Characterization and modulation of H2S production in fibroblasts derived from Down Syndrome individuals by time-lapse fluorescence imaging". Paper presented in FENS Regional Meeting, Albufeira, 2023.
  4. Agostinho, Rafaela. "Analysis of new corrole-based H 2 S fluorescent probes for cellular imaging". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  5. Agostinho, Rafaela; Simão, Sónia; Araújo, Inês. "New corrole-based H2S fluorescent probes for time-lapse imaging in cultured cells". Paper presented in IV Jornadas Algarve Biomedical Center (ABC), 2021.
Journal article
  1. Simão, Sónia; Agostinho, Rafaela; Martínez-Ruiz, Antonio; Araújo, Inês Maria. "Regulation of Ras Signaling by S-Nitrosylation". Antioxidants 12 8 (2023): 1562. http://dx.doi.org/10.3390/antiox12081562.
    10.3390/antiox12081562
Magazine article
  1. Agostinho, Rafaela; Simão, Sónia; Araújo, Inês. "Como é que a formação de novos neurónios é estimulada a seguir a uma lesão cerebral provocada por crises epilépticas?", Ualgoritmo - Ciência Trocada por Miúdos, 2021
Thesis / Dissertation
  1. Agostinho, Rafaela. "Papel da acetilação N-terminal na fertilidade e no envelhecimento". Master, Universidade do Algarve, 2020.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/01/26 Contribuition of S-nitrosylation of PDI to the aggregation and toxicity of alpha-synuclein in SH-SY5Y cells IX Clinical Biochemistry Workshop
Portuguese Society of Biochemistry (Faro, Portugal)
2019/11/19 Papel da acetilação N-terminal na fertilidade e no envelhecimento LabClub seminars
CBMR (Faro, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024/04 - 2024/06 Estabelecimento e caracterização de linhas de células progenitoras neuronais para o estudo do neurodesenvolvimento em pacientes com Síndrome de Down
Co-supervisor
 Ciências Biomédicas (Degree)
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2023/03 - 2023/06 Characterization of the contribution of S-nitrosylation to the aggregation of alpha-synuclein in Parkinson's Disease
Co-supervisor
 Ciências Biomédicas (Degree)
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2024/11/23 - 2024/11/23 Semana da Ciência e da Tecnologia 2023: Dinamização de atividade "Como manter o teu cérebro forte?" (2023/11/23 - 2023/11/23)
Seminar (Co-organisor)
 Centro Ciência Viva do Algarve, Portugal
2023/10/29 - 2023/11/04 Organizer of the workshop "Seeing is believing: time-lapse analysis of neuronal activity using fluorescent probes" at the ESN-ISN neurochemistry school 2023 (2023/10/29 - 2023/11/04)
Workshop (Other)
 Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2023/05/03 - 2023/05/05 Fens Regional Meeting 2023, 3rd-5th May 2023, Algarve, Portugal (2023/05/03 - 2023/05/05)
Congress (Other)
 Federation of European Neuroscience Societies, Belgium

Algarve Biomedical Center Research Institute, Portugal
2023/05/02 - 2023/05/02 VII Symposium Portuguese Glial Network (2023/05/02 - 2023/05/02)
Symposium (Other)
 Federation of European Neuroscience Societies, Belgium

Algarve Biomedical Center Research Institute, Portugal
2022/11/22 - 2022/11/22 Programa da Visita de Estudo UAlg “ DNA dentro da Célula”, “A Medicina na UAlg”. (2022/11/22 - 2022/11/22)
Seminar (Co-organisor)
 Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2024/01/31 - 2024/01/31 How to get Published and Get your Article Accepted in a Good Journal (with Elsevier UK) Workshop
Workshop
 How to get Published and Get your Article Accepted in a Good Journal (with Elsevier UK) Workshop
Centre for Doctoral Studies at King’s College London , United Kingdom
2022/05/03 - 2022/05/05 Dia Aberto - Universidade do Algarve
Meeting
 Dia Aberto
Universidade do Algarve - Campus de Gambelas, Portugal
2021/11/02 - 2021/11/02 ABC-RI Fall international forum | Neuroscience in Health and Diseases
Conference
Universidade do Algarve Algarve Biomedical Center, Portugal
2021/07/07 - 2021/07/08 Imaging in Neuroscience | Virtual conference
Conference
 Imaging in Neuroscience, Virtual Conference
2021/05/24 - 2021/05/29 The CRISPR Revolution: a workshop on Gene Editing
Workshop
 The CRISPR Revolution: a workshop on Gene Editing
Universidade do Algarve Centro de Investigação em Biomedicina, Portugal
2021 - 2021 Visita de estudo UAlg - Sessão experimental: DNA inside cells
Seminar
Universidade do Algarve Algarve Biomedical Center, Portugal
2020/11/23 - 2020/11/23 Organoids With]Out[ Borders | Online Symposium
Symposium
 Organoids With]Out[ Borders | 23 November 2020 | Online Symposium
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/04 - 2020/04 TAGC 2020 Online - The Allied Genetics Conference
Conference
 TAGC 2020 Online - The Allied Genetics Conference
Genetics Society of America, United States
2018/03/16 - 2018/03/16 II Jornadas Algarve Biomedical Center
Other
 II Jornadas Algarve Biomedical Center
Universidade do Algarve, Portugal
2016/11/10 - 2016/11/16 V Simpósio de Ciências Biomédicas, Faro
Symposium
 V Simpósio de Ciências Biomédicas, Faro
Universidade do Algarve, Portugal
2016/11/11 - 2016/11/12 II Jornadas da Saúde da Universidade do Algarve
Other
 II Jornadas da Saúde da Universidade do Algarve
Universidade do Algarve, Portugal
2016/11/11 - 2016/11/12 Técnicas de Suturas
Workshop
 Técnicas de Suturas
Universidade do Algarve, Portugal
2015/03/12 - 2015/03/14 IV Jornadas Nacionais de Ciências Biomédicas
Other
 IV Jornadas Nacionais de Ciências Biomédicas
Universidade do Algarve, Portugal

Association member

Society Organization name Role
2021 - Current Sociedade Portuguesa de Neurociências Adherent member
2021 - Current Federation of European Neuroscience Societies (FENS) Adherent member
2016/11 - 2017/12 Santa Casa da Misericórdia de Faro Volunteer at Santa Casa da Misericórdia of Faro, in the areas of animation and socialization

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2024/01 - 2024/06 Escrita Científica (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Algarve - Campus de Gambelas, Portugal
2023/07/01 - 2023/07/06 Brain Organoids Advanced Hands-on Course (40h) (Curso de mestrado (conclusão do curso de especialização)) Centre de Regulació Genòmica, Spain
2022/09/08 - 2022/09/09 Basic training on maintenance of Pluripotent Stem Cells (Curso de doutoramento (conclusão de unidades curriculares))
2022/09/01 - 2022/09/05 Hands-on Molecular Biology Tools - a beginners crash course (Curso de doutoramento (conclusão de unidades curriculares)) Fundação Champalimaud, Portugal
2022/03/17 - 2022/03/19 Online Course “Scientific tools in biological assays: principles of cell cultures and genetics” “Scientific tools in biological assays: principles of cell cultures and genetics” (Curso de mestrado (conclusão do curso de especialização)) Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/11/08 - 2021/11/12 PhD Advance Course Stem Cell Technologies PhD Advance Course Stem Cell Technologies (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Lisboa Faculdade de Farmácia, Portugal

Fundação Champalimaud, Portugal
Distinctions

Award

2024 Best Oral Communication Award
Universidade do Algarve - Campus de Gambelas, Portugal