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After graduating in Biology in 2012, I completed a Master’s Degree in Forensic Medicine at the University of Porto in 2014. During my Master’s, I joined the Addiction Biology and Glial Cell Biology Group at the Institute for Molecular and Cell Biology (IBMC) of the University of Porto. In 2017, I started a PhD in Neurosciences at the Faculty of Medicine of the University of Porto (FMUP), funded by an FCT doctoral fellowship. As a team member of the FCT project PsychoGlia at Summavielle's lab (i3S), I investigated the molecular mechanisms regulating psychostimulant-induced microglia activation. In this study, I demonstrated that methamphetamine promotes astrocytic glutamate release through an IP3R2/Ca²¿-dependent signaling pathway, which is critical for microglia reactivity. These findings led to a first-author publication in Neuropsychopharmacology (cover, 2021). To date, I am author/co-author of 10 peer-reviewed articles with a 5-year average impact factor of 7.4. I obtained my PhD degree with distinction in January 2022. During my PhD, I participated in several national and international scientific meetings, presenting my work through oral communications and poster presentations. I also attended specialized courses and workshops, continuously expanding my skills, knowledge, and scientific network. In 2022, I was awarded the first-place travel grant to attend Neuro2022 in Japan, where I presented my work as an oral communication. I was also invited to join scientific committees as an evaluator for the 6th i3S PhD Symposium and the 8th Molecular and Cell Biology Symposium (Porto, Portugal). I have supervised 5 undergraduate students, 4 master’s students, and several ERASMUS+ students. Currently, I supervise 2 PhD students, 1 ERASMUS+ student, and 4 undergraduates, reflecting my autonomy, sense of responsibility, and scientific maturity. Additionally, I have been responsible for laboratory management and logistics, further strengthening my independence as a researcher. Beyond research, I have engaged in science outreach activities, including press interviews (Diário de Notícias, August 21, 2021: “Metanfetamina: Investigadores portugueses descobrem mecanismo para prevenir recaídas”) and the organization of the workshop “Smart Drugs” for high school students. These initiatives aimed to disseminate scientific knowledge to the general public, fostering a better understanding of our research and its societal impact. During Brain Awareness Week (Ciência Viva initiative), I organized and conducted the activity “Exploring the Brain: A Journey into Differences” for primary and middle-grade students. As a Junior Researcher at the Addiction Biology Group at i3S, I studied the impact of substances of abuse, such as alcohol, on glial cell physiology. Currently, I am a Postdoctoral Researcher at the Life and Health Sciences Research Institute (ICVS), where I am investigating the role of astrogliogenesis in the adult brain.
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Identification

Personal identification

Full name
Teresa Correia Soares Canedo Calado

Citation names

  • Canedo, T.
  • Canedo, Teresa

Author identifiers

Ciência ID
241E-A08B-C124
ORCID iD
0000-0002-4000-153X
Researcher Id
ABD-6791-2020
Scopus Author Id
57193930267

Email addresses

  • teresasoares.canedo@gmail.com (Professional)
  • b13804@med.uminho.pt (Professional)

Telephones

Telephone
  • 253 604800 (Professional)

Addresses

  • Instituto de Investigação em Ciências da Vida e Saúde (ICVS), Escola de Medicina, Universidade do Minho, Campus de Gualtar, 4710-057, Braga, Braga, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Biochemistry
  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Health Sciences - Substance Abuse

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Education
Degree Classification
2025/01/17 - 2025/04/08
Ongoing
 Course on Innovation, Entrepreneurship and Leadership (Outros)
International Mentoring Foundation for the Advancement of Higher Education (IMFAHE), United States
2017/09 - 2022/01
Concluded
 Neurosciences (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
"Unveiling the cellular and molecular players involved in methamphetamine-induced neuroinflammation: focus on astrocyte-microglial crosstalk." (THESIS/DISSERTATION)
 Approved with Distinction
2019/10/07 - 2019/10/08
Concluded
 Flow Cytometry Workshop - From basic knowledge to advanced applications (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015/07/14 - 2015/07/14
Concluded
 Introdutory Course on Glial Biology (Outros)
XII European Meeting on Glial Cells in Health and Disease, Bilbao, Spain, Spain
2015/04 - 2015/05
Concluded
 Introductory Animal Science Course, following FELASA recommendations for B category (Outros)
Institute for Molecular and Cell Biology (IBMC), Porto, Portugal, Portugal
2012/09 - 2014/12
Concluded
 Forensic Medicine (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"The role of microglia in methamphetamine exposure" (THESIS/DISSERTATION)
2014/11/07 - 2014/11/08
Concluded
 Profiling alterations in microglia dynamic properties by neuroinflammation (Outros)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2013/04/15 - 2013/05/17
Concluded
 Initial Pedagogical Professional Training Course – Certificate of Pedagogical Skills (CPS) (Diploma de especialização)
I9PROJECT, Portugal
2009/09 - 2012/07
Concluded
 Biology (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
2012/05/15 - 2012/05/18
Concluded
 II Workshop on Cancer Research: biological and molecular basis (Outros)
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Affiliation

Science

Category
Host institution 		Employer
2023/11/27 - Current Postdoc (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2022/06/16 - 2023/10/15 Researcher (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Others

Category
Host institution 		Employer
2017/06/01 - 2022/01/14 PhD Student in Doctoral Programme in Neurosciences Fundação para a Ciência e a Tecnologia, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
(...)
2016/05/01 - 2017/05/31 Fellowship for Master's Graduates Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2014/12/16 - 2016/04/30 Volunteer Researcher Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2013/11/01 - 2014/12/15 Master Student at the Addiction Biology and Glial Cell Biology groups Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Projects

Grant

Designation Funders
2024/09/01 - Current Prefrontal Serotonin Signaling to Revert Cognitive Inflexibility in Stress-related Disorders
2023.14830.PEX
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2023/12/30 Increasing Vitamin C uptake in Microglia for halting Alzheimer's disease
EXPL/MED-NEU/0588/2021
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2018/06/01 - 2021/05/30 Psychostimulant-induced neuroinflammation: new insight in the crosstalk between microglia, astrocytes and neurons
PTDC/SAU-TOX/30647/2017
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2023/11/27 - Current Hippocampal connectivity and behavioral performance in health and depression: where does adult astrogliogenesis stand?
10.54499/2022.02201.PTDC
Post-doc Fellow
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2022/06/16 - 2023/10/15 Advanced therapeutic approaches in addiction: targeting neuroinflammation
PTDC/SAU-TOX/0067/2021
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2017/06/01 - 2022/01/14 Unveiling the cellular and molecular players involved in methamphetamine induced neuroinflammation: focus on astrocyte-microglial crosstalk.
SFRH/BD/117148/2016
PhD Student Fellow
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/05/01 - 2017/05/31 Operant behavioral tasks for evaluation of cognition, anxiety, fear and other complex behaviours in animal models
NORTE-01-0145-FEDER-000008
Master Student Fellow
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
Outputs

Publications

Conference abstract
  1. Santos-Pereira M.; Silva S.; Santos-Leite L.; Silva A.I.; Terceiro A.F.; Canedo, T.; Monteiro F.; Summavielle T.. "The insula, a key brain area for bladder pain control, is modulated by stress". Paper presented in 38th Annual EAU Congress, Milan, 2023.
    Published
  2. Almeida, Tiago O.; Socodato, Renato; Portugal, CC; Canedo, T.; Santos, ECS; Moreira, Joana; Magalhães, A.; et al. "Studying the microglia cytoskeleton: impact of Rho GTPase ablation in microglia morphology and function". Paper presented in XV European Meeting on Glial Cells in Health and Disease (virtual), Marseille, 2021.
    Published
  3. Socodato, Renato; Portugal, CC; Canedo, T.; Vaz, Sandra H.; Batista, Filipa; Summavielle, Teresa; Brakebusch, C.; et al. "RhoGTPase regulation of redox homeostasis in microglia". Paper presented in Free Radical Biology and Medicine, 2019.
    Published
  4. Portugal, Camila; Socodato, Renato; Canedo, T.; Henriques, JF; Silva, CM; Magalhães, J; Coelho-Santos, Vanessa ; Bettencourt Relvas, João. "Profilin-1 deficiency specifically in microglia leads to microglial disfunction, blood-brain barrier dysfunction and changes in mice behavior". Paper presented in XIV European Meeting on Glial Cells in Health and Disease, Porto, 2019.
    Published
  5. Canedo, T.; Portugal, CC; Socodato, Renato; Magalhães, J.D.; Bravo, J.; Relvas, J.B.; Summavielle, T.. "Methamphetamine induced neuroimmune response: an interaction between astrocytes and microglia". Paper presented in XIV European Meeting on Glial Cells in Health and Disease, Porto, 2019.
    Published
  6. Socodato, Renato; Portugal, Camila; Canedo, T.; Henriques, JF; Vaz, JF; Magalhães, J; Silva, CM; Bettencourt Relvas, João. "RhoA signaling in microglia and the impact for neurodegeneration". Paper presented in XIV European Meeting on Glial Cells in Health and Disease, Porto, 2019.
    Published
  7. Bravo, J.; Ribeiro, I.; Canedo, T.; Lopes, C.; Summavielle, T.. "Psychostimulant abuse and neuroinflammation: a crosstalk between glial cells and neurons". Paper presented in XIV European Meeting on Glial Cells in Health and Disease, Porto, 2019.
    Published
  8. Socodato, Renato; Camila C. Portugal; Canedo, T.; Henriques, JF; Vaz, Sandra H.; Magalhães, J; Silva, CM; et al. "Molecular mechanisms regulating glia homeostasis". 2018.
    Published • 10.1016/j.freeradbiomed.2018.04.071
  9. Cossenza, M.; Socodato, Renato; Portugal, CC; Canedo, T.; Oliveira, NA; Paes-De-Carvalho, R.; Bettencourt Relvas, João. "The role of coffee constituents other than caffeine on CSK/Src pathway in the Central Nervous System". Paper presented in Purines 2018 International, 2018.
  10. Socodato, Renato; Portugal, CC; Martins, T.; Canedo, T.; Silva, C; Domith, I.; Oliveira, N.; et al. "Specific downregulation of RhoA triggers microglia pro-inflammatory signature via Rock2/Csk/c-Src signaling pathway". Paper presented in XII European Meeting on Glial Cells in Health and Disease, Bilbao, 2015.
    Published
  11. Canedo, T.; Portugal, CC; Socodato, R.; Bettencourt Relvas, João; Summavielle, T.. "Astrocytes as a key partner in Methamphetamine-induced Microglia activation". Paper presented in XII European Meeting on Glial Cells in Health and Disease, Bilbao, 2015.
    Published
  12. Portugal, CC; Socodato, R.; Canedo, T.; Silva, C.; Martins, T.; Coreixas, V.S.M.; Loiola, E.C.; et al. "The Sodium Vitamin C co-Transporter-2 (SVCT2): a key molecule for microglia physiology". Paper presented in XII European Meeting on Glial Cells in Health and Disease, Bilbao, 2015.
    Published
Conference poster
  1. Raquel Pacheco; Canedo, T.; Rodrigues Ana Margarida; Joana Tedim-Moreira; Bettencourt Relvas, João; Renato Socodato; Cristina P. Vieira ; Summavielle, Teresa. "Untangling sex differences in glia-to-neuron communication in chronic alcohol exposure". Paper presented in Young Researchers Meeting of U.Porto (IJUP), 2025.
  2. Raquel Pacheco; Canedo, Teresa; Ana M. Rodrigues; Joana Tedim-Moreira; Joao B. Relvas; Summavielle, Teresa. "Deciphering neuroimmune interactions in alcohol intake in mouse model of intermittent access in male and female". Paper presented in Young Researchers Meeting of U.Porto (IJUP), 2024.
  3. Ana Filipa Terceiro; Canedo, Teresa; Ana Isabel Silva; Ana Magalhães; Bettencourt Relvas, João; Summavielle, Teresa. "The role of rac1 in methamphetamine-induced neuroinflammation". Paper presented in VIII Symposium Portuguese Glial Network, 2024.
  4. Camila C. Portugal; Evelyn C. S. Santos; Pacheco, Ana M.; Joana Tedim-Moreira; Tiago O. Almeida; Dora Gavin; Canedo, Teresa; et al. "Restoring vitamin c transport in microglia improves synaptic function and restrains cognitive impairments in neurodegenerative diseases". Paper presented in VIII Symposium Portuguese Glial Network, 2024.
  5. Ana Isabel Silva; Renato Socodato; Carolina Pinto; Ana Filipa Terceiro; Canedo, Teresa; Bettencourt Relvas, João; Margarida Saraiva; Summavielle, Teresa. "Il-10 and cdc42 as critical modulators in methamphetamine-induced neuroinflammation". Paper presented in VIII Symposium Portuguese Glial Network, 2024.
  6. Terceiro, Ana F.; Lobo, Andrea; Canedo, Teresa; Socodato, Renato; Carvalhais, Lia; Aroso, Miguel; Sousa, Mafalda; et al. "Rho GTPases in the spotlight: unveiling methamphetamine's effects on neuronal remodeling in the hippocampus". Paper presented in Neuroscience 2023, 2023.
  7. Rodrigues, João; Bravo, Joana; Bonifácio Andrade, Elva; Canedo, Teresa; Azevedo, Maria; Summavielle, Teresa. "Regulation of CD47 expression byinterferon-gamma under chronic Methamphetamine exposure". Paper presented in IJUP 2023, 2023.
  8. Galvão-Ferreira, João; Almeida, Tiago O.; Socodato, Renato; Camila C. Portugal; Santos, Evelyn C.S.; Tedim-Moreira, Joana; Canedo, Teresa; Summavielle, Teresa; Bettencourt Relvas, João. "Characterization of microglial response to Environmental Enrichment: The role of the RhoGTPase Rac1". Paper presented in Fens Regional Meeting 2023, 2023.
  9. Rodrigues, João; Bravo, Joana; Bonifácio Andrade, Elva; Azevedo, Maria; Summavielle, Teresa; Canedo, Teresa. "Microglia-Neuron crosstalk in chronicMethamphetamine exposure: regulation ofCD47 expression by interferon-gamma". Paper presented in FENS Regional Meeting 2023, 2023.
  10. Margarida Rodrigues; Canedo, T.; Ana Filipa Terceiro; Joana Tedim-Moreira; Silva, Ana Isabel; Ana Magalhães; Bettencourt Relvas, João; Summavielle, Teresa. "Deciphering the astrocytic and synaptic changes under chronic alcohol exposure using a self-administration paradigm". Paper presented in FENS Regional Meeting 2023, 2023.
  11. Margarida Rodrigues; Canedo, T.; Ana Filipa Terceiro; Joana Tedim-Moreira; Silva, Ana Isabel; Ana Magalhães; Bettencourt Relvas, João; Summavielle, Teresa. "Deciphering the astrocytic and synaptic changes under chronic alcohol exposure using a self-administration paradigm". Paper presented in VII Symposium for the Portuguese Glial Network, 2023.
  12. Rodrigues, João; Bravo, Joana; Bonifácio Andrade, Elva; Canedo, Teresa; Azevedo, Maria; Summavielle, Teresa. "Microglia-Neuron crosstalk in chronicmethamphetamine exposure". Paper presented in VIISymposium of the Portuguese GliaNetwork, 2023.
  13. Terceiro, Ana F.; Canedo, Teresa; Silva, Ana I; Magalhães, Ana; Relvas, João B.; Summavielle, Teresa. "Methamphetamine activates rac1 in striatal microglia". Paper presented in VII Symposium of the Portuguese Glial Network, 2023.
  14. Margarida Rodrigues; Canedo, T.; Ana Filipa Terceiro; Joana Tedim-Moreira; Silva, Ana Isabel; Ana Magalhães; Bettencourt Relvas, João; Summavielle, Teresa. "Deciphering the astrocytic and synaptic changes under chronic alcohol exposure using a self-administration paradigm". Paper presented in 9th McBiology Symposium, 2023.
  15. Pacheco, Ana M.; Santos, ECS; Almeida, Tiago O.; Socodato, Renato; Canedo, Teresa; Moreira, Joana; Bettencourt Relvas, João; Portugal, CC. "Increasing Ascorbate Transport in Microglia for Halting Alzheimer's Disease". Paper presented in 2nd Symposium on Alzheimer's Disease: An Update on pathology and Therapeutics, 2023.
  16. Ana Filipa Terceiro; Andrea C. Lobo; Canedo, T.; Lia Carvalhais; Aroso, Miguel; Mafalda Sousa; Socodato, Renato; et al. "Methamphetamine-induced modulation of RhoGTPases in hippocampal neurons and microglia". Paper presented in Neuro-immune interactions in health and disease organised by the Hertie Foundation and the Federation of European Neuroscience Societies, 2023.
  17. Terceiro, Ana F.; Lobo, Andrea; Canedo, Teresa; Carvalhais, Lia; Aroso, Miguel; Sousa, Mafalda; Socodato, Renato; et al. "Methamphetamine-induced modulation of RhoGTPases in hippocampal neurons and microglia (Presented by A. Terceiro)". Paper presented in n FENS-Hertie Winter School on Neuro-Immune Interactions in Health and Disease, 2023.
  18. Terceiro, Ana F.; Lobo, Andrea; Canedo, T.; Carvalhais, Lia; Aroso, Miguel; Sousa, Mafalda; Magalhães, Ana; et al. "Methamphetamine remodelling of hippocampal neurons is orchestrated via cdc42 pathway". Paper presented in VI Symposium of the Portuguese Glial Network, 2022.
  19. Ana Isabel Silva; Carolina Pinto; Ana Filipa Terceiro; Teresa Canedo; Ana Magalhães; João Bettencourt Relvas; Margarida Saraiva; Summavielle, Teresa. "Psychostimulant-induced neuroinflammation: the protective role of IL-10". Paper presented in Portuguese Society for Neuroscience (SPN) 2021, Coimbra, Portugal, 2021.
  20. Teresa Canedo; Ana I Silva; Elva B Andrade; Tiago O Almeida; António R Pombinho; André F Maia; Joana Bravo; et al. "Unveiling the mechanism of methamphetamine-induced neuroinflammatory response: focus on astrocyte to microglia glutamatergic signaling". Paper presented in Portuguese Society for Neuroscience (SPN) 2021, Coimbra, Portugal, 2021.
  21. Silva, Ana I.; Pinto, Carolina; Terceiro, Ana F.; Canedo, Teresa; Magalhães, Ana; Relvas, João B.; Saraiva, Margarida; Summavielle, Teresa. "Psychostimulant-induced neuroinflammation: the protective role of IL-10". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  22. Canedo, T.; Silva, Ana I.; Andrade, Elva B.; Almeida, Tiago O.; Pombinho, António R.; Maia, André F.; Bravo, Joana; et al. "Unveiling the mechanism of methamphetamine-induced neuroinflammarory response: focus on astrocyte to microglia glutamatergic signaling". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  23. Renato Socodato; Almeida, Tiago O.; Camila C. Portugal; Evelyn C. S. Santos; Joana Tedim-Moreira; Teresa Canedo; Filipa I. Baptista ; et al. "Microglia remodel the synaptic signaling required for context-dependent cognitive performance". Paper presented in IV Symposium of Portuguese Glial Network, 2021.
  24. A. F. Terceiro; A. Lobo; T. Canedo; A. I. Silva; J. Relvas; T. Summavielle. "Psychostimulant-induced neuroinflammation: the role of RhoGTPases in microglia". Paper presented in 5 th Molecular and Cell Biology Symposium, 2021.
  25. A. I. Silva; T. Canedo; A. F. Terceiro; J. B. Relvas ; M. Saraiva; T. Summavielle. "Psychostimulant-induced neuroinflammation: the protective role of IL-10". Paper presented in 5 th Molecular and Cell Biology Symposium, 2021.
  26. Canedo, T.; Portugal, C.C.; Socodato, R.; Magalhães, J.D.; Bravo, J.; Magalhães, A.; Relvas, J.B.; Summavielle, T.. "Neuroimmune response induced by methamphetamine". Paper presented in i3S Annual Meeting, Póvoa do Varzim., 2019.
  27. Rodrigues, A.; Portugal, C.C.; Canedo, T.; Summavielle, T.; Socodato, R.; Relvas, J.B.. "Deciphering the role of RhoA in microglia inflammation". Paper presented in i3S Annual Meeting, Póvoa do Varzim., 2019.
  28. Bravo, J.; Ribeiro, I.; Canedo, T.; Lopes, C.; Summavielle, T.. "A neuron-glia crosstalk under exposure to methamphetamine". Paper presented in Lisbon Addictions, October 2019, Lisbon., 2019.
  29. Canedo, T.; Portugal, C.C.; Socodato, R.; Magalhães, J.D.; Bravo, J.; Magalhães, A.; Relvas, J.B.; Summavielle, T.. "Methamphetamine induced neuroimmune response: an interaction between astrocytes and microglia". Paper presented in XIV European Meeting on Glial Cells in Health and Disease, Porto., 2019.
  30. Portugal, C.C.; Socodato, R.; Canedo, T.; Henriques, J.F.; Silva, C.M.; Ferreira, M.M.; Magalhães, J.; et al. "Profilin-1 deficiency specifically in microglia leads to microglial disfunction, blood-brain barrier dysfunction and changes in mice behaviour". Paper presented in XIV European Meeting on Glial Cells in Health and Disease, Porto., 2019.
  31. Bravo, J.; Ribeiro, I.; Canedo, T.; Lopes, C.; Summavielle, T.. "Psychostimulant abuse and neuroinflammation: a crosstalk between glial cells and neurons". Paper presented in XIV European Meeting on Glial Cells in Health and Disease, July 2019, Porto., 2019.
  32. Portugal, Camila; Socodato, Renato; Canedo, Teresa; Henriques, Joana F.; Silva, Cátia M; Ferreira, Mélanie M.; Magalhães, João; et al. "Profilin-1 deficiency specifically in microglia leads to microglial dysfunction, blood-brain barrier disruption and changes im mice bahaviour". Paper presented in IV Portuguese Glial Networking, Glia Diversity in Neuromodulation and Neurodegeneration, 2019.
  33. Canedo, T.; Portugal, C.C.; Socodato, R.; Magalhães, J.D.; Bravo, J.; Magalhães, A.; Relvas, J.B.; Summavielle, T.. "Microglia-astrocytes interaction in neuroinflammation under methamphetamine exposure". Paper presented in XVI Meeting of the Portuguese Society for Neuroscience, Lisbon., 2019.
  34. Bravo, J.; Ribeiro, I.; Canedo, T.; Lopes, C.; Summavielle, T.. "Methamphetamine and neuroinflammation: unveiling the crosstalk between glial cells and neurons". Paper presented in XVI Meeting of the Portuguese Society for Neuroscience, Lisbon., 2019.
  35. Canedo, T.; Portugal, C.C.; Socodato, R.; Magalhães, J.D.; Bravo, J.; Magalhães, A.; Relvas, J.B.; Summavielle, T.. "Astrocyte-microglia crosstalk in neuroinflammation induced by methamphetamine". Paper presented in 6th Venusberg Meeting on Neuroinflammation, Bonn., 2019.
  36. Portugal, C.C.; Socodato, R.; Canedo, T.; Henriques, J.F.; Silva, C.M.; Ferreira, M.M.; Magalhães, J.; et al. "Conditional ablation of Profilin-1 in microglia leads to microglial dysfunction, blood-brain barrier disruption and changes in mice behaviour". Paper presented in 6th Venusberg Meeting on Neuroinflammation, Bonn., 2019.
  37. Bravo, J.; Ribeiro, I.; Canedo, T.; Lopes, C.; Summavielle, T.. "Methamphetamine and neuroinflammation: a crosstalk between glial cells and neuron". Paper presented in 6th Venusberg Meeting on Neuroinflammation, Bonn., 2019.
  38. Portugal, C.C.; Socodato, R.; Canedo, T.; Henriques, J.F.; Silva, C.M.; Ferreira, M.M.; Magalhães, J.; et al. "Profilin-1 deficiency specifically in microglia leads to microglial dysfunction, blood-brain barrier disruption and changes in mice behaviour". Paper presented in IV Symposium of Portuguese Glial Network, Lisbon., 2019.
  39. Bravo, Joana; Ribeiro, Inês; Canedo, Teresa; Lopes, Cátia DF; Summavielle, Teresa. "Methamphetamine and neuroinflammation: a crosstalk between glial cells and neurons". Paper presented in 6th Venusberg Meeting on Neuroinflammation, 2019.
  40. Canedo, T.; Portugal, C.C.; Socodato, R.; Magalhães, J.D.; Bravo, J.; Magalhães, A.; Relvas, J.B.; Summavielle, T.. "Astrocyte-microglia crosstalk mediates the neuroinflammatory effects of methamphetamine". Paper presented in i3S Annual Meeting, Póvoa do Varzim., 2018.
  41. Henriques, J.; Socodato, R.; Portugal, C.C.; Alves, R.L.; Magalhães, J.; Canedo, T.; Magalhães, A.; et al. "Microglial Src-to-TNF signaling is implicated in the antigenic effect of ethanol in adult mice". Paper presented in III Symposium of Portuguese Glial Network, Porto., 2018.
  42. Portugal, C.C.; Socodato, R.; Canedo, Teresa; Henriques, J.F.; Silva, C.M.; Ferreira, M.M.; Magalhães, J.; et al. "Profilin-1 deficiency specifically in microglia leads to microglial disfunction, blood brain barrier disruption and cognitive deficits". Paper presented in III Symposium of Portuguese Glial Network, Porto., 2018.
  43. Bravo, J.; Lobo, A.; Canedo, Teresa; Relvas, J.B.; Summavielle, T.. "Methamphetamine and neuroinflammation: The crosstalk between microglia and neuronal cells". Paper presented in III Symposium of Portuguese Glial Network, Porto., 2018.
  44. Canedo, T.; Portugal, C.C.; Socodato, R.; Magalhães, J.D.; Bravo, J.; Magalhães, A.; Relvas, J.B.; Summavielle, T.. "The neuroimmune response induced by methamphetamine depends on an astrocyte-microglia crosstalk". Paper presented in III Symposium of Portuguese Glial Network, Porto., 2018.
  45. Canedo, Teresa; Portugal, C.C.; Socodato, R.; Magalhães, A.; Relvas, J.B.; Summavielle, T.. "Unveiling the mechanisms involved in methamphetamine-induced neuroinflammation: astrocyte-microglial crosstalk". Paper presented in 5th Venusberg Meeting on Neuroinflammation, Bonn., 2017.
  46. Socodato, R.; Portugal, C.C.; Martins, T.; Canedo, Teresa; Henriques, J.F.; Magalhães, J.; Silva, C.M.; et al. "Microglia homeostasis requires RhoA and its conditional ablation leads to phenotypes commonly associated with neurological disorders". Paper presented in 5th Venusberg Meeting on Neuroinflammatio, Bonn., 2017.
  47. Portugal, C.C.; Socodato, R.; Canedo, Teresa; Silva, C.M.; Martins, T.; Coreixas, V.S.M.; Loiola, E.C.; et al. "Caveolin-1-mediated internalization of the vitamin C transporter SVCT2 in microglia triggers an inflammatory phenotype". Paper presented in 5th Venusberg Meeting on Neuroinflammation, Bonn., 2017.
  48. Canedo, Teresa; Portugal, C.C.; Socodato, R.; Magalhães, A.; Relvas, J.B.; Summavielle, T.. "Methamphetamine-induced neuroimmune response: focus on astrocyte-microglia crosstalk". Paper presented in XV Meeting of the Portuguese Society for Neuroscience, Braga., 2017.
  49. Bravo, J.; Lobo, A.; Canedo, Teresa; Relvas, J.B.; Summavielle, T.. "Methamphetamine and neuroinflammation: The crosstalk between microglia and neuronal cells". Paper presented in XV Meeting of the Portuguese Society for Neuroscience, Braga., 2017.
  50. Henriques, J.; Portugal, C.C.; Magalhães, A.; Canedo, Teresa; Silva, C.M.; Relvas, J.B.; Summavielle, T.; Socodato, R.. "The antigenic effect of ethanol in adult mice requires TNF production from microglia". Paper presented in XV Meeting of the Portuguese Society for Neuroscience, Braga., 2017.
  51. Portugal, C.C.; Socodato, R.; Canedo, T.; Silva, C.M.; Martins, T.; Coreixas, V.S.M.; Loiola, E.C.; et al. "Caveolin-1-mediated internalization of the vitamin C transporter SVCT2 in microglia triggers an inflammatory phenotype". Paper presented in 5th Venusberg Meeting on Neuroinflammation, Bonn., 2017.
  52. Canedo, Teresa; Portugal, C.C.; Socodato, R.; Bravo, J.; Magalhães, A.; Relvas, J.B.; Summavielle, T.. "Unveiling the cellular and molecular players involved in methamphetamine-induced neuroinflammation: focus on astrocyte-microglial crosstalk". Paper presented in 5th i3S annual meeting, Póvoa de Varzim, 2016.
  53. Portugal, C.C.; Silva, C.M.; Canedo, Teresa; Socodato, R.; Relvas, J.B.. "Profilin-1 is essential for microglial homeostasis in the adult brain". Paper presented in 5th i3S Annual Meeting, Póvoa de Varzim, 2016.
  54. Socodato, R.; Portugal, C.C.; Canedo, Teresa; Henriques, J. F.; Silva, C.M.; Baptista, F. I.; Alves, R.L.; et al. "The small GTPase RhoA is essential for microglial homeostasis and its conditional ablation leads to phenotypes commonly associated with neurological disorders". Paper presented in 5th i3S Annual Meeting, Póvoa de Varzim., 2016.
  55. Socodato, R.; Portugal, C.C.; Martins, T.; Canedo, Teresa; Silva, C.M.; Domith, I.C.L.; Oliveira, N.A.; et al. "Specific downregulation of RhoA triggers microglia pro-inflammatory signature via Rock2/Csk/c-Src signaling pathway". Paper presented in XII European Meeting on Glial Cells in Health and Disease, Bilbao, 2015.
  56. Portugal, C.C.; Socodato, R.; Canedo, Teresa; Silva, C.M.; Martins, T.; Coreixas, V.S.M.; Loiola, E.C.; et al. "The Sodium Vitamin C co-Transporter 2 (SVCT2): A key molecule for microglia physiology". Paper presented in XII European Meeting on Glial Cells in Health and Disease, Bilbao, 2015.
  57. Canedo, Teresa; Portugal, C.C.; Socodato, R.; Relvas, J.B.; Summavielle, T.. "Astrocytes as a key partner in Methamphetamine-induced Microglia activation". Paper presented in XII European Meeting on Glial Cells in Health and Disease, Bilbao, 2015.
  58. Portugal, C.C.; Socodato, R.; Canedo, Teresa; Silva, C.M.; Martins, T.; Coreixas, V.S.M.; Loiola, E.C.; et al. "The Sodium Vitamin C co-Transporter 2 (SVCT2) downregulation is necessary and sufficient to induce microglia pro-inflammatory activation". Paper presented in XIV Meeting of the Portuguese Society for Neuroscience, Póvoa de Varzim, 2015.
  59. Socodato, R.; Portugal, C.C.; Canedo, Teresa; Silva, C.M.; Summavielle, T.; Relvas, J.B.. "Ethanol triggers fast glutamate release from cortical microglia via c-Src/TNF signaling". Paper presented in XIV Meeting of the Portuguese Society for Neuroscience, Póvoa de Varzim, 2015.
  60. Canedo, Teresa; Portugal, C.C.; Socodato, R.; Relvas, J.B.; Summavielle, T.. "Unveiling the role of astrocytes in methamphetamine-induced microglia activation". Paper presented in XIV Meeting of the Portuguese Society for Neuroscience, Póvoa de Varzim, 2015.
  61. Socodato, R.; Portugal, C.C.; Martins, T.; Canedo, Teresa; Silva, C.M.; Domith, I.C.L.; Oliveira, N.A.; et al. "Specific downregulation of RhoA triggers a pro-inflammatory signature in microglia via a Rock2/Csk/c-Src signaling axis". Paper presented in 4th Venusberg-Meeting on Neuroinflammation, Bonn, 2015.
  62. Portugal, C.C.; Socodato, R.; Canedo, Teresa; Silva, C.M.; Martins, T.; Coreixas, V.S.M.; Loiola, E.C.; et al. "Sodium Vitamin C co-Transporter 2 (SVCT2) downregulation is necessary and sufficient to induce a pro-inflammatory polarization of microglia". Paper presented in 4th Venusberg-Meeting on Neuroinflammation, Bonn, 2015.
  63. Canedo, Teresa; Portugal, C.C.; Socodato, R.; Relvas, J.B.; Summavielle, T.. "Methamphetamine-induced microglia activation: The role of astrocytes". Paper presented in 4th Venusberg-Meeting on Neuroinflammation, Bonn, 2015.
  64. Socodato, R.; Portugal, C.C.; Martins, T.; Canedo, Teresa; Silva, C.M.; Domith, I.C.L.; Oliveira, N.A.; et al. "RhoA downregulation in microglia is sufficient to trigger a pro-inflammatory signature". Paper presented in 5th PF2MUC Symposium "Zoom in Microglia", Coimbra, 2014.
  65. Portugal, C.C.; Socodato, R.; Martins, T.; Canedo, Teresa; Silva, C.M.; Coreixas, V.S.M.; Loiola, E.C.; et al. "Downregulation of sodium vitamin C co-transporter-2 (SVCT-2) is a key step in the pro-inflammatory signature of microglial cells". Paper presented in 5th PF2MUC Symposium "Zoom in Microglia", Coimbra, 2014.
  66. Canedo, Teresa; Portugal, C.C.; Socodato, R.; Relvas, J.B.; Summavielle, T.. "Understanding methamphetamine-mediated microglial cells activation". Paper presented in 5th PF2MUC Symposium "Zoom in Microglia", Coimbra, 2014.
  67. Canedo, Teresa; Portugal, C.C.; Socodato, R.; Relvas, J.B.; Summavielle, T.. "Methamphetamine does not regulate the proinflammatory signature of cortical microglial cells in culture". Paper presented in 4th ANNUAL MEETING IBMC| INEB|IPATIMUP, Póvoa de Varzim, 2014.
Journal article
  1. Portugal, Camila; Almeida, Tiago; Moreira, Joana; Silva, Cátia; Canedo, Teresa; Galvão, João; Magalhaes, Ana; et al. "Disrupting the microglial cytoskeleton accelerates senescence and causes premature synaptic aging". Nature Communications (2025):
    Under revision
  2. Silva, Ana Isabel; Socodato, Renato; Pinto, Carolina; Terceiro, Ana Filipa; Canedo, T.; Relvas, João Bettencourt; Saraiva, Margarida; Summavielle, Teresa. "IL-10 and Cdc42 modulate astrocyte-mediated microglia activation in methamphetamine-induced neuroinflammation". Glia (2024): http://dx.doi.org/10.1002/glia.24542.
    10.1002/glia.24542
  3. Renato Socodato; Tiago O. Almeida; Camila C. Portugal; Evelyn C.S. Santos; Joana Tedim-Moreira; João Galvão-Ferreira; Teresa Canedo; et al. "Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance". Cell Reports (2023): http://dx.doi.org/10.1016/j.celrep.2023.113447.
    10.1016/j.celrep.2023.113447
  4. Renato Socodato; Artur Rodrigues-Santos; Joana Tedim-Moreira; Tiago Almeida; Teresa Canedo; Camila C. Portugal; Joao B. Relvas. "RhoA balances microglial reactivity and survival during neuroinflammation". Cell Death & Disease (2023): http://dx.doi.org/10.1038/s41419-023-06217-w.
    10.1038/s41419-023-06217-w
  5. Socodato, R.; Rodrigues-Santos, A.; Tedim-Moreira, J.; Almeida, T.O.; Canedo, T.; Portugal, C.C.; Relvas, J.B.. "Correction: RhoA balances microglial reactivity and survival during neuroinflammation". Cell Death and Disease 14 12 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85178947443&partnerID=MN8TOARS.
    10.1038/s41419-023-06340-8
  6. Portugal, Camila; Monteiro-Pacheco, Ana; Santos, ECS; Canedo, T.; Almeida, Tiago O.; Moreira, Joana; Oliveira, Fabiana;; Bettencourt Relvas, João. "Increasing the vitamin C transporter SVCT2 in microglia suppresses pathology and cognitive impairment in Alzheimer's disease". Journal of Neurochemistry 39 B 04-09 (2023): 102-103. http://dx.doi.org/10.1111/jnc.15897.
    10.1111/jnc.15897
  7. Joana Bravo; Ines Ribeiro; Ana Filipa Terceiro; Elva Bonifácio Andrade; Camila Portugal; Igor Moreira Lopes; Maria M. Azevedo; et al. "Neuron-Microglia Contact-Dependent Mechanisms Attenuate Methamphetamine-Induced Microglia Reactivity and Enhance Neuronal Plasticity". Cells (2022): https://www.mdpi.com/2073-4409/11/3/355.
    10.3390/cells11030355
  8. Canedo, T.; Portugal, Camila Cabral; Socodato, Renato; Almeida, Tiago Oliveira; Terceiro, Ana Filipa; Bravo, Joana; Silva, Ana Isabel; et al. "Astrocyte-derived TNF and glutamate critically modulate microglia activation by methamphetamine". Neuropsychopharmacology 46 13 (2021): 2358-2370. http://dx.doi.org/10.1038/s41386-021-01139-7.
    10.1038/s41386-021-01139-7
  9. Renato Socodato; Joana F. Henriques; Camila C. Portugal; Tiago O. Almeida; Joana Tedim-Moreira; Renata L. Alves; Teresa Canedo; et al. "Daily alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior". Science Signaling (2020): https://doi.org/10.1126/scisignal.aba5754.
    10.1126/scisignal.aba5754
  10. Socodato, Renato; Portugal, Camila C.; Canedo, Teresa; Rodrigues, Artur; Almeida, Tiago O.; Henriques, Joana F.; Vaz, Sandra H.; et al. "Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration". Cell Reports 31 12 (2020): 107796. http://dx.doi.org/10.1016/j.celrep.2020.107796.
    10.1016/j.celrep.2020.107796
  11. Henriques, J.F.; Portugal, C.C.; Canedo, T.(241E-A08B-C124); Relvas, J.B.; Summavielle, T.; Socodato, R.. "Microglia and alcohol meet at the crossroads: Microglia as critical modulators of alcohol neurotoxicity.". Toxicology Letters 283 (2018): 21-31. http://www.scopus.com/inward/record.url?eid=2-s2.0-85034097322&partnerID=MN8TOARS.
    10.1016/j.toxlet.2017.11.002
  12. Portugal, C.C.; Socodato, R.; Canedo, T. (241E-A08B-C124); Silva, C.M.; Martins, T.; Coreixas, V.S.M.; Loiola, E.C.; et al. "Caveolin-1-mediated internalization of the vitamin C transporter SVCT2 in microglia triggers an inflammatory phenotype". Science Signaling 10 472 (2017): eaal2005-eaal2005. https://doi.org/10.1126/scisignal.aal2005.
    10.1126/scisignal.aal2005
  13. Socodato, R.; Portugal, C.C.; Canedo, T.; Domith, I.; Oliveira, N.A.; Paes-De-Carvalho, R.; Relvas, J.B.; Cossenza, M.. "C-Src deactivation by the polyphenol 3-O-caffeoylquinic acid abrogates reactive oxygen species-mediated glutamate release from microglia and neuronal excitotoxicity". Free Radical Biology and Medicine 79 (2015): 45-55. http://www.scopus.com/inward/record.url?eid=2-s2.0-84919622998&partnerID=MN8TOARS.
    10.1016/j.freeradbiomed.2014.11.019
Online resource
  1. Socodato, R.; Portugal, C.C.; Canedo, T. (241E-A08B-C124); Domith, I.; Oliveira, N.A.; Paes-de-Carvalho, R.; Relvas, J.B.; Cossenza, M.. c-Src deactivation by the polyphenol 3-O-caffeoylquinic acid abrogates reactive oxygen species-mediated glutamate release from microglia and neuronal excitotoxicity. 2015. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000350392900004&KeyUID=WOS:000350392900004.
    10.1002/glia.22767
Preprint
  1. Portugal, Camila C.; Santos, Evelyn C. S.; Pacheco, Ana M.; Costa-Pinto, Sara; Almeida, Tiago O.; Tedim-Moreira, Joana; Gavin, Dora; et al. "Increasing the vitamin C transporter SVCT2 in microglia improves synaptic plasticity and restrains memory impairments in Alzheimer's disease models". 2024. http://dx.doi.org/10.1101/2024.02.29.582679.
    10.1101/2024.02.29.582679
  2. Canedo, T.; Portugal, Camila Cabral; Socodato, Renato; Bravo, Joana; Almeida, Tiago Oliveira; Magalhães, João D.; Guerra-Gomes, Sónia; et al. "Astrocyte-derived TNF and glutamate critically modulate microglia reactivity by methamphetamine". 2021. http://dx.doi.org/10.1101/2021.02.22.432170.
    10.1101/2021.02.22.432170
  3. Socodato, Renato; Almeida, Tiago O.; Portugal, Camila C.; Santos, Evelyn C. S.; Tedim-Moreira, Joana; Canedo, T.; Baptista, Filipa I.; et al. "Rac1 signaling in microglia is essential for synaptic proteome plasticity and experience-dependent cognitive performance". 2021. http://dx.doi.org/10.1101/2021.10.18.464802.
    10.1101/2021.10.18.464802
  4. Socodato, Renato; Henriques, Joana F.; Portugal, Camila C.; Almeida, Tiago O.; Tedim-Moreira, Joana; Alves, Renata L.; Canedo, T.; et al. "Alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior". 2019. http://dx.doi.org/10.1101/870279.
    10.1101/870279
  5. Socodato, Renato; Portugal, Camila C.; Canedo, T.; Rodrigues, Artur; Almeida, Tiago O.; Henriques, Joana F.; Vaz, Sandra H.; et al. "Microglia dysfunction caused by the loss of Rhoa disrupts neuronal physiology and leads to neurodegeneration". 2017. http://dx.doi.org/10.1101/218107.
    10.1101/218107
Thesis / Dissertation
  1. "Unveiling the cellular and molecular players involved in methamphetamine - induced neuroinflammation: focus on astrocyte-microglial crosstalk". PhD, Universidade do Porto Faculdade de Medicina, 2022. https://hdl.handle.net/10216/139356.
  2. "The role of microglia in methamphetamine exposure". Master, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 2014. https://repositorio-aberto.up.pt/handle/10216/77676.

Other

Dataset
  1. Canedo, T.. Transcriptomic profiles of microglia from wild-type control and methamphetamine-treated mice. Gene Expression Omnibus (GEO), acession number GSE180497. 2021.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/11/20 Restoring microglial Vitamin C Transport as a Novel Strategy to Treat dementia-related Neurodegenerative Diseases 1st Iberian Glial Networks Symposium
Portuguese Glial Network and Spanish Glial Network
2024/11/12 Enhancing Microglial Vitamin C transport as a novel strategy to treat Alzheimer's Disease XII Neuroscience Symposium of Federal Fluminense University (UFF) and the VII UFF/Fiocruz Neuroscience Symposium
Universidade Federal Fluminense (UFF), Fundação Oswaldo Cruz (Fiocruz) (Rio de Janeiro, Brazil)
2024/04/05 Microglial rac1 drives experience-dependent brain plasticity VIII Symposium Portuguese Glial Network
(Braga, Portugal)
2023/09/15 Increase Ascorbate Transport in Microglia Prevents Disease Progression in a Pre-clinical Mouse Model for Studying Alzheimer's Disease 18th YES (Young European Scientist) Meeting
Faculty of Medicine, University of Porto (Porto, Portugal)
2023/05/02 Increasing Ascorbate Transport in Hippocampal Microglia Prevents Disease Progression in Aß-Depositing Mice VII Symposium of the Portuguese Glial Network
Portuguese Glial Network (Albufeira, Portugal)
2022/07/02 Unveiling the mechanism of methamphetamine-induced neuroinflammarory response: focus on astrocyte to microglia glutamatergic signaling Neuro2022
(Okinawa, Japan)
2021/12/02 Psychostimulant-induced neuroinflammation: the protective role of IL-10 XVII Meeting of the Portuguese Society of Neuroscience
(Coimbra, Portugal)
2021/11/30 PsychoGlia: A crosstalk between glial cells under psychoactive drugs IV Symposium of Portuguese Glial Network
(Coimbra, Portugal)
2021/11/30 Increasing vitamin C uptake in microglia for halting Alzheimer's disease IV Symposium of Portuguese Glial Network
(Coimbra, Portugal)
2021/03/12 Exploring glial cells in drug context VI SBE - Bioengineering Week 2021
IST (Lisbon, Portugal)
2021/01 Neuroinflammation and substance abuse: partners in crime Neuroscience seminars
Lisbon Medical School (Lisbon, Portugal)
2020/11/17 The role of neuroinflammation in substance abuse XV Congresso da AEFFUP
Faculty of Pharmacy - Student Nucleus (Porto, Portugal)
2020/11 The relevance of neuroinflammation for the addictive behaviour DICAS (National Health System)
(Porto, Portugal)
2019/10/23 An astrocyte-microglia crosstalk mediating neuroinflammation under exposure to psychostimulants Lisbon Addictions 2019
SICAD (Lisboa, Portugal)
2019/07/11 RhoA signaling in microglia and the impact for neurodegeneration XIV European Meeting on Glial Cells in Health and Disease
(Porto, Portugal)
2019/05/29 TNF and glutamate dependent microglia reactivity under a psychoactive drug IV Symposium of Portuguese Glial Network
Portuguese Glial Network (Lisbon, Portugal)
2019/03/17 Neuroinflammation and drug addiction, partners in crime? X National Event for Biomedical Sciences (JNBC)
Universidade de Aveiro (Aveiro, Portugal)
2018/05/17 Padrões de exposição binge e desregulação neuroimune Encontro de Adições de Cascais
(Cascais, Portugal)
2018/03/14 Neuroinflamação na exposição a psicoestimulantes: uma conversa cruzada entre neurónios e glia Seminários da Faculdade de Medicina da Universidade do Porto
FMUP (Porto, Portugal)
2017/05/24 Sodium Vitamin C co-Transporter-2 (SVCT2): A critical molecule for microglial physiology II Symposium of the Portuguese Glial Network
Portuguese Glial Network (Braga, Portugal)
2017/05/24 Microglia homeostasis requires RhoA and its conditional ablation leads to phenotypes commonly associated with neurological disorders II Symposium of the Portuguese Glial Network
Portuguese glial Network (Braga, Portugal)
2017/05/24 New insights on psychostimulant regulation of microglia activation II Symposium of the Portuguese Glial Network
ICVS (Braga, Portugal)
2017/03/09 The addicted brain: a neuronal disease or a crosstalk between different neuronal players? IV AEICBAS Biomedical Conference
AEICBAS (Porto, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2025/05/01 - Current AstroMap: Understanding Adult Astrogliogenesis in Health and Depression
Supervisor of Leandro José Rodrigues Freitas
 Biomedicina e Ciências da Saúde (PhD)
Universidade do Minho, Portugal
2025/03/17 - Current Mapping Adult Astrogliogenesis Influence in Health and Depression
Supervisor of Adriana Vieira
 Medicina (Degree)
Universidade do Minho, Portugal
2025/03/17 - Current Implications of Astrogliogenesis in the Adult Brain for Health and Disease: A Systematic Review
Supervisor of Juliana Carvalho
 Medicina (Master)
Universidade do Minho, Portugal
2024/09/17 - Current Molecular Portraits: Unraveling Exosomal Signatures of Adult-Born Astrocytes in Depression Pathophysiology
Supervisor of Ana Catariana Monteiro Pacheco
 Biomedicina e Ciências da Saúde (PhD)
Universidade do Minho Escola de Ciências da Saúde, Portugal
2025/03/05 - 2025/06/27 Mapping Adult Astrogliogenesis Influence in Health and Depression
Supervisor of Vasiliki Lazarou
Erasmus Plus, Belgium
2024/03/10 - 2025/04/17 Desvendando a Especificidade Viral para a Marcação Seletiva de Novos Astrócitos Gerados no Hipocampo Adulto: Uma Abordagem Inovadora
Supervisor of Adriana Vieira
 Medicina (Degree)
Universidade do Algarve, Portugal
2024/12/10 - 2025/03/14 Decoding the role of mouse adult-born astrocytes in hippocampal plasticity: from heath to depression
Supervisor of Inês Sofia Oliveira Maia
 Medicina (Degree)
Universidade do Minho, Portugal
2024/04/24 - 2024/06/21 Map the developmental and structural features of adult-born astrocytes in the hippocampal DG of mice
Co-supervisor of Bruno Leite Silva
 Bioquímica (Degree)
Universidade do Minho, Portugal
2022/09/01 - 2023/11/08 Deciphering how astrocytes and neuroimmune interactions modulate alcohol intake
Supervisor of Ana Margarida Bravo Rodrigues
 Neurobiologia
Universidade do Porto Faculdade de Medicina, Portugal
2019 - 2020 Acetyl-L-Carnitine's Role in the Metabolism of Astrocytes and Neurons Exposed to Methamphetamine
Co-supervisor of Mariana Isabel Cerqueira Nunes
 Biologia (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2018 - 2019 Modulating ascorbate transport to target neuroinflammation in Alzheimer´s Disease
Co-supervisor of Fabiana Raquel Silva Oliveira
 Biologia (Degree)
Universidade de Aveiro, Portugal
2018 - 2019 Deciphering the role of RhoA in microglia inflammation
Co-supervisor of Artur Santos Rodrigues
 Biologia Celular e Molecular (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2017 - 2018 Rac1 regulation of microglia homeostasis and activation during neuroinfammation
Co-supervisor of Tiago de Oliveira Almeida
 Neurobiologia (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2016 - 2017 Role of Profilin-1 in Microglial function
Co-supervisor of Mélanie Mendes Ferreira
 Biologia (Scientific initiation)
Universidade de Aveiro, Portugal
2015 - 2017 Mechanisms of alcohol modulation of microglial function
Co-supervisor of Joana Fernandes Henriques
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2024/03/14 - 2024/03/14 Organized and led the activity 'Exploring the Brain: A Journey into Differences' with 6th year students at Escola Básica Padre António Luís Moreira. (2024/03/11 - 2024/03/17)
Other (Co-organisor)
 Ciência Viva, Portugal
2024/03/12 - 2024/03/12 Organized and led the activity 'Exploring the Brain: A Journey into Differences' with 4th year students at Colégio Chapim Azul (2024/03/11 - 2024/03/17)
Other (Co-organisor)
 Ciência Viva, Portugal
2024/03/12 - 2024/03/12 Organized and led the activity 'Exploring the Brain: A Journey into Differences' with 4th year students at Escola Básica Padre António Luís Moreira. (2024/03/12 - 2024/03/12)
Other (Co-organisor)
 Ciência Viva, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2025/03/13 - 2025/03/13 Conducted a sensory activity with 2nd year students from Colégio Alfacoop
Other
 Brain Awareness Week
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2024/06/12 - 2024/06/14 The 5th Eurogenesis Meeting took place on June 12–14, 2024, at the University of Bordeaux, France. The event gathered researchers and students to discuss recent advances in adult hippocampal neurogenesis, from cellular mechanisms to therapeutic applications.
Conference
 Adult Neurogenesis in Physiology and Disease
Neurocentre Magendie, France

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2024/07/19 Dissecting the Biology of Begain in Neuroglial Cells
(Thesis) Main arguer
 Luís Castro Fernandes Benge (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024/07/17 Advanced New Therapeutic Approaches in Addiction: Targeting Neuroinflammation
(Thesis) Main arguer
 Constança Santos Almeida Cabral (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024/06/21 Mapping the Developmental and Structural Features of Adult-Born Astrocytes in the Hippocampal DG of Mice
Supervisor
 Bruno Leite Silva (Other)
Universidade do Minho, Portugal
2023/11/08 Deciphering How Astrocytes and Neuroimmune Interactions Modulate Alcohol Intake
Supervisor
 Ana Margarida Bravo Rodrigues (Master)
Universidade do Porto Faculdade de Medicina, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2022/10 - Current Journal of Neuroimmune Pharmacology Springer Nature
2022/06 - Current Metabolic Brain Disease Springer Nature
2022/05 - Current Neurochemical Research Springer Nature
2022/04 - Current Scientific Reports Springer Nature

Association member

Society Organization name Role
2017 - Current Portuguese Glial Network Member

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2024/10/03 - 2024/10/03 Advanced Studies in Neurosciences Biomedicina e Ciências da Saúde (Doutoramento) Universidade do Minho, Portugal
2021/11/25 - 2021/11/25 Cognitive Improvement (Outros)

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2023/10/03 - 2023/10/04 Member of the scientific committee of the 6th i3S PhD Symposium
Evaluator
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/04/04 - 2022/04/04 Member of the scientific committee of the 8th Molecular and Cell Biology Symposium
Evaluator
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2021/08/21 Metanfetaminas: Investigadores portugueses descobrem mecanismo para prevenir recaídas, Diário de Notícias Diário de Notícias
Distinctions

Award

2023 First Prize in the Plenary Session of the 18th YES (Young European Scientist) Meeting
Fundação AstraZeneca, Portugal
2023 First Prize in the Neurosciences Parallel Oral Session of the 18th YES (Young European Scientist) Meeting
Fundação Professor Ernesto Morais, Portugal
2022 First Place Travel Award: Neuro2022, Okinawa, Japan
2021 Best Poster Award: "V Symposium of the Portuguese Glial Network", Coimbra, Portugal
2015 Participation fellowship: "XIV Meeting of the Portuguese Society for Neurosciences" Póvoa de Varzim, Portugal
Serviço de Intervenção nos Comportamentos Aditivos e nas Dependências IP, Portugal
2014 Best Poster Award: "Zoom in Microglia", Coimbra, Portugal
Instituto Biomédico de Investigação da Luz e da Imagem - Universidade de Coimbra, Portugal

Other distinction

2021 Cover of Neuropsychopharmacology, December 2021, Volume 46, Issue 13
2020 Editorial Note in Science: Leslie K. Ferrarelli. Tipsy microglia binge on synapses. Science 25 Sep 2020: Vol. 369, Issue 6511, pp. 1579 https://science.sciencemag.org/content/369/6511/twis.full; Altmetric score 312 - top 5% of all research outputs score
2020 Cover of Science Signaling, September 2020, Volume 13, Issue 650