| Conference abstract |
- Lima, Aurea; Bernardes, Miguel; Azevedo, Rita; Medeiros, Rui; Seabra, Vítor. "Rumo à Medicina Personalizada na Artrite Reumatoide:
Polimorfismos no Gene ATIC como Preditores Farmacogenéticos da Resposta Clínica ao Metotrexato". Paper presented in IV
Simpósio SPR - Imagiologia, Póvoa do Varzim, 2015.
Published
- Lima, Aurea; Bernardes, Miguel; Azevedo, Rita; Medeiros, Rui; Seabra, Vítor. "Poderão os Polimorfismos no Gene MTHFR Predizer
o Perfil de Resposta Clínica ao Metotrexato em Doentes com Artrite Reumatoide?". Paper presented in IV Simpósio SPR - Imagiologia,
Póvoa do Varzim, 2015.
Published
- Lima, Aurea; Bernardes, Miguel; Azevedo, Rita; Medeiros, Rui; Seabra, Vítor. "Polimorfismos no ADORA2A como Preditores da
Toxicidade ao Metotrexato na Artrite Reumatoide: Um Passo em Direção à Medicina Personalizada". Paper presented in IV Simpósio
SPR - Imagiologia, IV Simpósio SPR - Imagiologia, 2015.
Published
- Lima, Aurea; Bernardes, Miguel; Sousa, Hugo; Azevedo, Rita; Medeiros, Rui; Seabra, Vítor. "Prediction of Methotrexate Therapeutic
Outcome: Can an Index Risk be more important than a Haplotype approach?". Paper presented in Second ESPT Conference "Pharmacogenomics:
From Cell to Clinic", Lisboa, 2014.
Published
- Lima, Aurea; Seabra, Vítor; Bernardes, Miguel; Azevedo, Rita; Sousa, Hugo; Medeiros, Rui. "Role of key TYMS polymorphisms
on Methotrexate therapeutic outcome in Rheumatoid Arthritis Portuguese patients". Paper presented in Second ESPT Conference
"Pharmacogenomics: From Cell to Clinic", Lisboa, 2014.
Published
- Lima, Aurea; Seabra, Vítor; Bernardes, Miguel; Azevedo, Rita; Sousa, Hugo; Medeiros, Rui. "TYMS polymorphisms and methotrexate
therapeutic outcome in rheumatoid arthritis Portuguese patients: analysis of key polymorphisms". Paper presented in European
League Against Rheumatism Congress 2014, Paris, 2014.
Published
- Lima, Aurea; Azevedo, Rita; Sousa, Hugo; Bernardes, Miguel; Medeiros, Rui; Seabra, Vítor. "SLC19A1, SLCO1B1 and ABCG2 polymorphisms
are associated with Methotrexate-related gastrointestinal toxicity in Portuguese rheumatoid arthritis patients". Paper presented
in European League Against Rheumatism Congress 2014, Paris, 2014.
Published
- Lima, Aurea; Bernardes, Miguel; Azevedo, Rita; Sousa, Hugo; Seabra, Vítor; Medeiros, Rui. "SLC22A11 T allele (rs11231809)
as a predictor of Methotrexate non-response in Portuguese rheumatoid arthritis patients". Paper presented in XVII Congresso
Português de Reumatologia, Algarve, 2014.
Published
|
| Conference poster |
- Freitas, Rui; Relvas-Santos, Marta; Pereira Azevedo, Ana Rita ; Soares, Janine; Fernandes, Elisabete; Beatriz Teixeira; Santos,
Lúcio; Silva, André M. N.; Ferreira, José Alexandre. Corresponding author: Ferreira, José Alexandre. "Enzymatic synthesis
of cancer-associated O-glycopeptides libraries and multivalent protein glycoconjugates: translating synthetic glycoepitopes
into cancer glycovaccines". Paper presented in First Summer School in Biomedical Glycoscience, 2022.
- Peixoto, Andreia; Fernandes, Elisabete; Gaiteiro, Cristiana; Lima, Luís; Azevedo, Rita; Soares, Janine; Cotton, Sofia; et
al. "Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation".
Paper presented in 29th International Carbohydrate Symposium (ICS 2018) by Peixoto A, 2018.
|
| Journal article |
- Moona Sakari; Rajendra Bhadane; Sujit Kumar; Rita Azevedo; Morteza Malakoutikhah; Ahmadreza Masoumi; Dene R. Littler; et al.
"ADP-ribosyltransferase-based biocatalysis of nonhydrolyzable NAD+ analogs". Journal of Biological Chemistry (2025):
https://doi.org/10.1016/j.jbc.2024.108106.
10.1016/j.jbc.2024.108106
- Ferreira E; Ferreira D; Relvas-Santos M; Freitas R; Soares J; Azevedo R; Afonso LP; et al. "Aberrantly Glycosylated GLUT1
as a Poor Prognosis Marker in Aggressive Bladder Cancer.". International journal of molecular sciences (2024): http://europepmc.org/abstract/med/38542435.
10.3390/ijms25063462
- Jacquemin C; Villain N; Azevedo R; Boluda S; Thévenot EA; Fenaille F; Lamari F; Becher F. "Evaluation of SP3 for antibody-free
quantification of tau in CSF mimic and brain by mass spectrometry.". European journal of mass spectrometry (Chichester,
England) (2024): http://europepmc.org/abstract/med/38258392.
10.1177/14690667231218912
- "Mass Spectrometry for Neurobiomarker Discovery: The Relevance of Post-Translational Modifications". Cells 11 8 (2022):
1279-1279. http://dx.doi.org/10.3390/cells11081279.
10.3390/cells11081279
- Gaiteiro, Cristiana; Soares, Janine; Relvas-Santos, Marta; Peixoto, Andreia; Ferreira, Dylan; Paulo, Paula; Brandão, Andreia;
et al. "Glycoproteogenomics characterizes the CD44 splicing code associated with bladder cancer invasion". Theranostics
12 7 (2022): 3150-3177. http://dx.doi.org/10.7150/thno.67409.
10.7150/thno.67409
- Peixoto A; Ferreira D; Azevedo R; Freitas R; Fernandes E; Relvas-Santos M; Gaiteiro C; et al. "Glycoproteomics identifies
HOMER3 as a potentially targetable biomarker triggered by hypoxia and glucose deprivation in bladder cancer.". Journal
of experimental & clinical cancer research : CR (2021): http://europepmc.org/abstract/med/34108014.
10.1186/s13046-021-01988-6
- Sofia Cotton; Dylan Ferreira; Janine Soares; Andreia Peixoto; Marta Relvas-Santos; Rita Azevedo; Paulina Piairo; et al. "Target
Score—A Proteomics Data Selection Tool Applied to Esophageal Cancer Identifies GLUT1-Sialyl Tn Glycoforms as Biomarkers of
Cancer Aggressiveness". International Journal of Molecular Sciences 22 4 (2021): 1664-1664. https://doi.org/10.3390/ijms22041664.
10.3390/ijms22041664
- Freitas, R.; Relvas-Santos, M.; Azevedo, R.; Soares, J.; Fernandes, E.; Teixeira, B.; Santos, L.L.; et al. "Single-pot enzymatic
synthesis of cancer-associated MUC16: O -glycopeptide libraries and multivalent protein glycoconjugates: A step towards cancer
glycovaccines". New Journal of Chemistry 45 20 (2021): 9197-9211. http://www.scopus.com/inward/record.url?eid=2-s2.0-85106745147&partnerID=MN8TOARS.
10.1039/d0nj06021f
- Elisabete Fernandes; Rui Freitas; Dylan Ferreira; Janine Soares; Rita Azevedo; Cristiana Gaiteiro; Andreia Peixoto; et al.
"Nucleolin-Sle A Glycoforms as E-Selectin Ligands and Potentially Targetable Biomarkers at the Cell Surface of Gastric Cancer
Cells". Cancers (2020): https://doi.org/10.3390/cancers12040861.
10.3390/cancers12040861
- Peixoto A; Relvas-Santos M; Azevedo R; Santos LL; Ferreira JA. "Protein Glycosylation and Tumor Microenvironment Alterations
Driving Cancer Hallmarks.". Frontiers in oncology (2019): http://europepmc.org/abstract/med/31157165.
10.3389/fonc.2019.00380
- Manuel Neves; Rita Azevedo; Luís Lima; Marta I. Oliveira; Andreia Peixoto; Dylan Ferreira; Janine Soares; et al. "Exploring
sialyl-Tn expression in microfluidic-isolated circulating tumour cells: A novel biomarker and an analytical tool for precision
oncology applications". New Biotechnology 49 (2019): 77-87. https://doi.org/10.1016/j.nbt.2018.09.004.
10.1016/j.nbt.2018.09.004
- Azevedo R; Soares J; Gaiteiro C; Peixoto A; Lima L; Ferreira D; Relvas-Santos M; et al. "Glycan affinity magnetic nanoplatforms
for urinary glycobiomarkers discovery in bladder cancer.". Talanta (2018): http://europepmc.org/abstract/med/29674052.
10.1016/j.talanta.2018.03.028
- Azevedo R; Gaiteiro C; Peixoto A; Relvas-Santos M; Lima L; Santos LL; Ferreira JA. "CD44 glycoprotein in cancer: a molecular
conundrum hampering clinical applications.". Clinical proteomics (2018): http://europepmc.org/abstract/med/29983670.
10.1186/s12014-018-9198-9
- Rita Azevedo; Janine Soares; Andreia Peixoto; Sofia Cotton; Luís Lima; Lúcio Lara Santos; José Alexandre Ferreira. "Circulating
tumor cells in bladder cancer: Emerging technologies and clinical implications foreseeing precision oncology". Urologic
Oncology: Seminars and Original Investigations 36 5 (2018): 221-236. https://doi.org/10.1016/j.urolonc.2018.02.004.
10.1016/j.urolonc.2018.02.004
- Carrascal MA; Silva M; Ferreira JA; Azevedo R; Ferreira D; Silva AMN; Ligeiro D; et al. "A functional glycoproteomics approach
identifies CD13 as a novel E-selectin ligand in breast cancer.". Biochimica et biophysica acta (2018): http://europepmc.org/abstract/med/29777742.
10.1016/j.bbagen.2018.05.013
- Rita Azevedo; André M.N. Silva; Celso A. Reis; Lúcio Lara Santos; José Alexandre Ferreira. "In silico approaches for unveiling
novel glycobiomarkers in cancer". Journal of Proteomics 171 (2018): 95-106. https://doi.org/10.1016/j.jprot.2017.08.004.
10.1016/j.jprot.2017.08.004
- Luís Lima; Manuel Neves; Marta I. Oliveira; Lorena Dieguez; Rui Freitas; Rita Azevedo; Cristiana Gaiteiro; et al. "Sialyl-Tn
identifies muscle-invasive bladder cancer basal and luminal subtypes facing decreased survival, being expressed by circulating
tumor cells and metastases". Urologic Oncology: Seminars and Original Investigations 35 12 (2017): 675.e1-675.e8. https://doi.org/10.1016/j.urolonc.2017.08.012.
10.1016/j.urolonc.2017.08.012
- Azevedo, Rita. "Over forty years of bladder cancer glycobiology: Where do glycans stand facing precision oncology?". Oncotarget
(2017):
10.18632/oncotarget.19433
- Cotton S; Azevedo R; Gaiteiro C; Ferreira D; Lima L; Peixoto A; Fernandes E; et al. "Targeted O-glycoproteomics explored increased
sialylation and identified MUC16 as a poor prognosis biomarker in advanced stage bladder tumours.". (2017): http://europepmc.org/abstract/med/28156048.
10.1002/1878-0261.12035
- Peixoto, A.; Fernandes, E.; Gaiteiro, C.; Lima, L.; Azevedo, R.; Soares, J.; Cotton, S.; et al. "Hypoxia enhances the malignant
nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension". Oncotarget 7 39 (2016):
63138-63157. http://www.scopus.com/inward/record.url?eid=2-s2.0-84994050563&partnerID=MN8TOARS.
10.18632/oncotarget.11257
- Lima, A.; Bernardes, M.; Azevedo, R.; Seabra, V.; Medeiros, R.; Lima A; Bernardes M; et al. "Moving toward personalized medicine
in rheumatoid arthritis: SNPs in methotrexate intracellular pathways are associated with methotrexate therapeutic outcome".
Pharmacogenomics 17 15 (2016): 1649-1674. http://www.scopus.com/inward/record.url?eid=2-s2.0-84991251048&partnerID=MN8TOARS.
10.2217/pgs-2016-0067
- Azevedo R; Ferreira JA; Peixoto A; Neves M; Sousa N; Lima A; Santos LL. "Emerging antibody-based therapeutic strategies for
bladder cancer: A systematic review.". (2015): http://europepmc.org/abstract/med/26196222.
10.1016/j.jconrel.2015.07.002
- Azevedo, Rita; Bernardes, Miguel; Fonseca, João; Lima, Aurea. "Smartphone application for rheumatoid arthritis self-management:
cross-sectional study revealed the usefulness, willingness to use and patients’ needs". Rheumatology International
1 (2015): 1-11. http://link.springer.com/article/10.1007%2Fs00296-015-3270-9.
Published • 10.1007/s00296-015-3270-9
- Azevedo, Rita; Sousa, Hugo; Monteiro, Joaquim; Lima, Aurea. "Future perspectives of Smartphone applications for rheumatic
diseases self-management". Rheumatology International 35 3 (2015): 419-431. http://link.springer.com/article/10.1007%2Fs00296-014-3117-9.
Published • 10.1007/s00296-014-3117-9
- Lima A; Bernardes M; Azevedo R; Medeiros R; Seabra V. "Pharmacogenomics of Methotrexate Membrane Transport Pathway: Can Clinical
Response to Methotrexate in Rheumatoid Arthritis Be Predicted?". (2015): http://europepmc.org/abstract/med/26086825.
10.3390/ijms160613760
- Lima A; Sousa H; Monteiro J; Azevedo R; Medeiros R; Seabra V; Lima, Aurea; et al. "Genetic polymorphisms in low-dose methotrexate
transporters: current relevance as methotrexate therapeutic outcome biomarkers.". Pharmacogenomics 15 12 (2014): 1611-1635.
http://europepmc.org/abstract/med/25340735.
Published • 10.2217/pgs.14.116
- Lima A; Bernardes M; Azevedo R; Monteiro J; Sousa H; Medeiros R; Seabra V. "SLC19A1, SLC46A1 and SLCO1B1 Polymorphisms As
Predictors Of Methotrexate-Related Toxicity In Portuguese Rheumatoid Arthritis Patients.". (2014): http://europepmc.org/abstract/med/25124723.
10.1093/toxsci/kfu162
- Lima, Aurea; Monteiro, Joaquim; Bernardes, Miguel; Sousa, Hugo; Azevedo, Rita; Seabra, Vítor; Medeiros, Rui. "Prediction of
methotrexate clinical response in Portuguese rheumatoid arthritis patients: Implication of MTHFR rs1801133 and ATIC rs4673993
polymorphisms". BioMed Research International 2014 368681 (2014): 1-14.
Published • 10.1155/2014/368681
- Lima, Aurea; Bernardes, Miguel; Sousa, Hugo; Azevedo, Rita; Costa, Lúcia; Ventura, Francisco; Seabra, Vítor; Medeiros, Rui.
"SLC19A1 80G allele as a biomarker of methotrexate-related gastrointestinal toxicity in Portuguese rheumatoid arthritis patients".
Pharmacogenomics 15 6 (2014): 807-820.
Published • 10.2217/pgs.13.244
- Lima A; Seabra V; Bernardes M; Azevedo R; Sousa H; Medeiros R. "Role of Key TYMS Polymorphisms on Methotrexate Therapeutic
Outcome in Portuguese Rheumatoid Arthritis Patients.". (2014): http://europepmc.org/abstract/med/25279663.
10.1371/journal.pone.0108165
- Lima, Aurea; Azevedo, Rita; Sousa, Hugo; Seabra, Vítor; Medeiros, Rui. "Current approaches for TYMS
polymorphisms and their importance in molecular epidemiology and pharmacogenetics". Pharmacogenomics 14 11 (2013):
1337-1413.
Published • 10.2217/pgs.13.118
|
