Sandra Cristina Almeida Paiva (2617-F4E9-8A01)

Curriculum Vitae

Sandra Cristina Almeida Paiva

SANDRA PAIVA is an Associate Professor with Habilitation at the Department of Biology (DB), and an integrated member of the Centre of Molecular and Environmental Biology (CBMA), at the School of Sciences (ECUM) of the University of Minho (UM). She is the Pro-Rector for Scientific Projects and Research Management at UMinho. She graduated in Biochemistry from the University of Porto and received a Master degree in Molecular Genetics and a Ph.D. in Sciences from ECUM. During her PhD, she was a visiting graduate student at the Jacques Monod Institute and at the École Normale Supérieure (Paris), University of Madrid and University of Amsterdam. Most recently, she was a Fulbright Visiting Scholar at the University of California, Berkeley. She received several awards and scholarships, like the American Club Annual Award (2001). She conducts research in the areas of Molecular Genetics and Cell Biology at the CBMA, supervising dozens of MSc and PhD students. She is a co-author of several indexed scientific publications, including in reference journals such as the Journal of Cell Biology having coordinated or participated in numerous research projects. She annually organizes an international advanced course for graduate students and she was part of an International Training Network -ITN. She develops her teaching activity in the areas of Genetics and Molecular Biology, Biochemistry, Trafficking and Cell Signaling. She was Vice- President of the School of Sciences, Director of the Degree in Applied Biology, Director of the Master Course in Applied Biochemistry, Director for the Society of CBMA, elected member of the Board of Directors of the DB and of the Scientific Council of ECUM. She was an elected member of the General Council of UMinho from 2017 to 2021. She was a member of the Commission for the creation of the Master Course in Science Communication. She designed and coordinated several outreach activities, such as the Science Festival, European Researchers Night, iSci-Interface Science. She is a member of the General Council of the Carlos Amarante Schools Group, in Braga, and was part of the Board of Directors of TecMinho and of the Casas do Conhecimento at UMinho. Over the past 20 years, Paiva’s group has been dissecting the mechanisms by which nutrient transporters at the plasma membrane are regulated to influence metabolic adaptations, stress responses or pathobiology. Her work is internationally recognized and she has been an invited Speaker at some of the most prestigious conferences and Universities, like Yale School of Medicine (Yale University), University of California Berkeley, Imperial College, University College London. She was recently the co-organizer of the EMBO meeting "Membrane transporters as essential elements of cellular function and homeostasis".

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Identification

Personal identification

Full name: Sandra Cristina Almeida Paiva
Gender: Female

Citation names

Paiva, Sandra

Author identifiers

Ciência ID: 2617-F4E9-8A01
ORCID iD: 0000-0003-2270-4546
Researcher Id: H-8864-2013
Scopus Author Id: 36830586500

Email addresses

spaiva@bio.uminho.pt (Professional)

Knowledge fields

Natural sciences - Biological Sciences - Molecular Biology

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
English	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)

Education

	Degree	Classification
2002 Concluded	Ciências (Doutoramento) Major in Sem especialidade Universidade do Minho, Portugal "Identification and Characterization of Plasma Membrane Monocarboxy Late Transporters in Saccharomyces Cerevisiae and Candida Albicans" (THESIS/DISSERTATION)	Aprovado por unanimidade
1999 Concluded	Genética Molecular (Mestrado integrado) Universidade do Minho, Portugal "Caracterização molecular de transportadores de ácidos monocarboxílicos em Saccharomyces cerevisiae" (THESIS/DISSERTATION)	Muito Bom
1991/10 - 1995/12 Concluded	Bioquímica (Licenciatura) Universidade do Porto, Portugal "Mutagenesis on the araE gene encoding for Arabinose-H+ Symport Protein of Escherichia coli" (THESIS/DISSERTATION)

Affiliation

Science

	Category Host institution	Employer
2004/10 - Current	Principal Investigator (Research)	Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
	Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2014/08/28 - 2015/01/23	Visiting Researcher (Research)	University of California Berkeley, United States
	University of California Berkeley, United States

Teaching in Higher Education

	Category Host institution	Employer
2002/11 - Current	Assistant Professor (University Teacher)	Universidade do Minho Departamento de Biologia, Portugal
	Universidade do Minho Departamento de Biologia, Portugal
1999/10 - 2002/04	Visiting Professor (University Teacher)	Universidade do Minho Escola Superior de Enfermagem, Portugal
	Universidade do Minho Escola Superior de Enfermagem, Portugal

Positions / Appointments

	Category Host institution	Employer
2021/11/29 - Current	Pro-Rector	Universidade do Minho, Portugal
	Universidade do Minho, Portugal
2016/04/02 - Current	Member of the Scientific Council of the School of Sciences, UMinho (elected)	Universidade do Minho Escola de Ciências, Portugal
	Universidade do Minho Escola de Ciências, Portugal
2018/09/01 - 2021/10/01	Member of the Course Commision of the Master Course in Science Communication	Universidade do Minho, Portugal
	Universidade do Minho, Portugal
2018 - 2021/10/01	Member of the Diretion Board of CBMA (Diretor for Society)	Universidade do Minho, Portugal
	Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2019/09/01 - 2021/09/01	Course Director of the Master Course in Applied Biochemistry	Universidade do Minho Escola de Ciências, Portugal
	Universidade do Minho Escola de Ciências, Portugal
2017/04/06 - 2021/09/01	Member of the General Council of the University of Minho (elected)	Universidade do Minho, Portugal
	Universidade do Minho, Portugal
2016/09/15 - 2017/09/15	Course Director of the Master Course in Applied Biochemistry	Universidade do Minho, Portugal
	Universidade do Minho, Portugal
2010/02/01 - 2016/06/01	Vice-President	Universidade do Minho, Portugal
	Escola de Ciências, Universidade do Minho, Portugal
2012/09 - 2014/09	Member of the Direction board	TecMinho Associação Universidade-Empresa para o Desenvolvimento, Portugal
	TecMinho Associação Universidade-Empresa para o Desenvolvimento, Portugal
2008/09/01 - 2010/08/31	Course Director of Applied Biology	Universidade do Minho, Portugal
	Universidade do Minho, Portugal

Others

	Category Host institution	Employer
2016/09/01 - 2022/10/01	Scientific Associate	International Iberian Nanotechnology Laboratory, Portugal
	International Iberian Nanotechnology Laboratory, Portugal

Projects

Contract

	Designation	Funders
2021/01/06 - Current	MetaFungal-Metabolism of carboxylic acids in Fungal Infections PTDC/BIA-MIC/5246/2020 Principal investigator Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2017/09/01 - 2021/08/31	YEASTDOC: Yeast Biotechnology Doctoral Training Programme Reference DLV-764927 Researcher	Horizon 2020 European Union Ongoing
2016/06/01 - 2019/05/31	EcoAgriFood: Innovative green products and processes to promote Agri-Food BioEconomy NORTE-01-0145-FEDER Researcher	Ongoing
2016/05/01 - 2019/05/01	Trans-acids: Structural-functional studies of carboxylic acid transporters: novel tools in production optimization using industrial microbes PTDC/BIA-MIC/5184/2014 Researcher	Fundação para a Ciência e a Tecnologia Ongoing
2016/05 - 2019/05	Trans-acids: Structural-functional studies of carboxylic acid transporters: novel tools in production optimization using industrial microbes PTDC/BIA-MIC/5184/2014	Fundação para a Ciência e a Tecnologia
2016/05/01 - 2017/12/01	Science in Everyday Life, SCILIFE H2020-MSCA-NIGHT-2016 Principal investigator	European Union Horizon 2020 Concluded
2016 - 2017	"My school of Sciences" - 2nd edition "My school of Sciences" - 2nd edition Principal investigator	Concluded
2016 - 2017	"My school of Sciences" - 2nd edition "My school of Sciences" - 2nd edition	N/A
2012/03/31 - 2015/08/31	Candida glabrata biofilms tolerance mechanisms to antifungic agents PTDC/SAU-MIC/119069/2010 Researcher	Fundação para a Ciência e a Tecnologia Concluded
2012/03 - 2015/08	Candida glabrata biofilms tolerance mechanisms to antifungic agents PTDC/SAU-MIC/119069/2010	Fundação para a Ciência e a Tecnologia
2011/09/01 - 2014/08/31	Networking Primary Science Educators as a means to provide training and professional development in Inquiry Based Teaching info:eu-repo/grantAgreement/EC/FP7/266647/EU Researcher	European Commission Concluded
2013/01/01 - 2014/07/01	"A minha Escola de Ciências" PEC 183 Principal investigator	Ciência Viva Concluded
2013/01 - 2014/07	"A minha Escola de Ciências" PEC 183	Ciência Viva
2011/10/01 - 2014/03/31	Creative Little Scientists: Enabling Creativity through Science and Mathematics in Preschool and First Years of Primary Education info:eu-repo/grantAgreement/EC/FP7/289081/EU	European Commission
2009 - 2012	MONOLIPO - MONOOLEIN-BASED LIPOPLEXES: PHYSICOCHEMICAL CHARACTERIZATION AND STUDY OF THEIR POTENTIAL AS NON-VIRAL VECTORS info:eu-repo/grantAgreement/FCT/5876-PPCDTI/69795/PT Researcher	European Commission Concluded
2008 - 2011	“GrapeBerryFactory - Sugars, acids, phenolics and water on grape berry development and ripening”. PTDC/AGR-ALI/100636/2008 Researcher	Concluded
2005/01/01 - 2007/12/31	PermYeast – Molecular biology of the monocarboxylic acids permeases in yeast: from functional to structural analysis POCI/BIA-BCM/57812/2004 Principal investigator	Fundação para a Ciência e a Tecnologia Concluded
2003 - 2006	EnoSafe – Segurança e controlo de qualidade de vinhos: implementação de técnicas rápidas para monitorização e rastreabilidade microbiológica Projecto 762 Researcher	Instituto Nacional de Investigação Agrária e Veterinária Concluded
2003 - 2005	Engineering of Saccharomyces cerevisiae species able to remove malic acid under genetic control POCTI/ BIO/38106/2001 Researcher	Fundação para a Ciência e a Tecnologia Concluded
2001 - 2004	Molecular and genetic analysis of monocarboxylic acid transporters in yeasts - JENesis POCTI/ 1999/ BME / 36625 Researcher	Fundação para a Ciência e a Tecnologia Concluded
1996 - 1999	Isolamento e caracterização de leveduras: aplicações em enologia (PAMAF 2029) PAMAF 2029 Researcher	Ministério da Agricultura Florestas e Desenvolvimento Rural Concluded
1996 - 1997	Optimização de Fermentações Alcoólicas: Construção de Estirpes da Levedura Saccharomyces cerevisiae com capacidade de remoção de ácidos fracos do meio de fermentação PRAXIS 2/2.1/BIO/1068/95 Researcher	Concluded

Outputs

Publications

Book chapter	Sandra Paiva. "O valor (in)estimável da Ciência Básica em tempo de pandemia". 295-309. {UMinho, 2020. 10.21814/uminho.ed.24.13 Casal, Margarida; Queirós, Odília; Talaia, Gabriel; Ribas, David; Paiva, Sandra. "Carboxylic Acids Plasma Membrane Transporters in Saccharomyces cerevisiae". In Advances in Experimental Medicine and Biology, 229-251. Springer International Publishing, 2016. Published • 10.1007/978-3-319-25304-6_9
Conference paper	Silva, E; Casal, M; Paiva, S; Queirós, O. "Subcellular localization of the monocarboxylate transporter Mct1 tagged with the green fluorescence protein in different cancer cell lines". 2012. Published • 10.1055/s-0032-1330825 Léon, Sébastien; Becuwe, Michel; Vieira, Neide; Lara, David; Casal, Margarida; Vincent, Olivier; Paiva, Sandra; Haguenauer-Tsapis, Rosine. "Connecting glucose signalling to ubiquitin-dependent transporter endocytosis: Arrestin the culprit!". Paper presented in 25th International Conference on yeast Genetics and Molecular Biology, Olsztyn, 2011. Published Queirós, Odília; Paiva, Sandra; Moradas-Ferreira, Pedro; Casal, Margarida. "Molecular and physiological characterization of monocarboxylic acids permeases in the yeast Kluyveromyces lactis.". Paper presented in XXI International Conference on Yeast Genetics and Molecular Biology, Göteborg, 2003. Published Paiva, Sandra; Soares-Silva, Isabel; Kötter, Peter; Entian, Karl-Dieter; Casal, Margarida. "The disruption of JEN1 from Candida albicans impairs the transport of lactate.". Paper presented in XXI International Conference on Yeast Genetics and Molecular Biology, Göteborg, 2003. Published Paiva, Sandra; Kruckeberg, Arthur L.; Casal, Margarida. "Catabolite inactivation of the lactate transporter in Saccharomyces cerevisiae: ubiquitination, endocytosis and degradation in the vacuole.". Paper presented in YEAST 2001: XXth International Conference on Yeast Genetics and Molecular Biology, Praga, 2001. Published Paiva, Sandra; Makuc, Judita; Schauen, Matthias; Krämer, Reinhard; André, Bruno; Casal, Margarida; Leão, Cecília; Boles, Eckhard. "The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane". Paper presented in 27th Meetting of the FEBS and Pan-American Association Molecular Biology, Lisboa, 2001. Published Paiva, S; Kruckeberg, A; Casal, M. "Catabolite inactivation of the lactate transporter in Saccharomyces cerevisiae: ubiquitination, endocytosis and degradation in the vacuole.". Paper presented in XXth International Conference on Yeast Genetics and Molecular Biology., 2001. Published Casal, Margarida; Paiva, Sandra; Andrade, Raquel P.; Leão, Cecília. "Genetic and functional analysis of the Saccharomyces cerevisiae gene JEN1 encoding the lactate permease.". Paper presented in XIX International Conference on Yeast Genetics and Molecular Biology, Rimini, 1999. Published Paiva, Sandra; Casal, Margarida; Leão, Cecília. "Genetic characterization of monocarboxylic acids transporters of Saccharomyces cerevisiae.". Paper presented in 16th Small Meeting on Yeast Transport and Energetics (SMYTE), Bratislava, 1998. Published
Conference poster	Gonçalves, Alexandra; Alves, Rosana; Casal, Margarida; Van Dijck, Patrick; Paiva, Sandra. "Candida glabrata biofilm development on medical devices is modulated by the presence of alternative carbon sources". Paper presented in MICROBIOTEC’17 – Congress of Microbiology and Biotechnology, 2017. Oliveira-Pacheco, João; Alves, Rosana; Cerqueira-Rodrigues, Bruno; Paiva, Sandra; Silva, Sónia; Henriques, Mariana; Sampaio, Paula. "Metabolic plasticity as a strategy for virulence: participation of Candida albicans transcription factor RLM1 in host-pathogen interaction.". Paper presented in I Symposium of Applied Biochemistry, 2017. Alves, Rosana; Dambournet, Daphné; Sorkin, Alexander; Miranda, Adelaide; De Beule, Pieter; Drubin, David; Paiva, Sandra. "Characterization of intracellular trafficking of nutrient transporters using combined fluorescence optical sectioning and nanomechanical mapping atomic force microscopy in mammalian cells.". Paper presented in XIX Annual Linz Winter Workshop, 2017. Barata-Antunes, Cláudia; Talaia, Gabriel; Alves, Rosana; Martins, Viviana; Gerós, Hernâni; Paiva, Sandra. "Heterologous expression of the Human Copper Transporters hCTR1 and hCTR2 in yeast for endocytic trafficking analysis". Paper presented in XIX National Congress of Biochemistry, 2016. Alves, Rosana; Kastora, Stravoula; Pinho, Eva Patrícia Paiva Santos; Rodrigues, Célia Fortuna; Silva, Sónia; Casal, Margarida; Brown, Alistair J.; Henriques, Mariana; Paiva, Sandra. "Impact of alternative carbon sources and antifungal treatment on Candida glabrata biofilms’ transcription profile". Paper presented in XIX National Congress of Biochemistry, 2016. Ribas, David; Sá-Pessoa, Joana; Paiva, Sandra; Soares-Silva, Isabel; Ruohonen, Laura; Penttilä, Merja; Casal, Margarida. "Yeast as a tool to express carboxylic acid transporters with biotechnological interest". Paper presented in XIX National Congress of Biochemistry, 2016. Talaia, Gabriel; Casal, Margarida; Diallinas, George; Paiva, Sandra. "Analysis of the intracellular traffic and turnover of yeast membrane transporters using a novel domain swap strategy.". Paper presented in 34th Small Meeting on Yeast Transport and Energetics, 2016. Ribas, David; Sá-Pessoa, Joana; Paiva, Sandra; Ruohonen, Laura; Penttilä, Merja; Casal, Margarida. "Yeast as a tool to express carboxylic acid transporters with biotechnological interest.". Paper presented in PYFF6 - Sixth Conference on Physiology of Yeasts and Filamentous Fungi, 2016. Alves, Rosana; Mota, Sandra; Barata, Cláudia; Silva, Sónia; Rodrigues, Célia Fortuna; Brown, Alistair J.; Henriques, Mariana; Casal, Margarida; Paiva, Sandra. "Carboxylic acid transportes Jen1 and Jen2 affect Candida albicans biofilms’ formation and susceptibility to fluconazole". Paper presented in XL Portuguese Genetics Conference, 2016. Maciel, Marina; Dias, Alice; Carvalho, Ana; Cunha, Ana; Gonçalves, Arminda Manuela; André, João Paulo; Gonçalves, Luís; et al. "AMEC nas empresas: Experimentar ciência em contexto empresarial". Paper presented in National Congress SciComPT 2016, 2016. Talaia, Gabriel; Casal, Margarida; Diallinas, George; Paiva, Sandra. "The study of the endocytic trafficking of the yeast monocarboxylate transporter Jen1 from Saccharomyces cerevisiae". Paper presented in XXXIX Portuguese Genetics Conference, 2015. Mota, Sandra; Vieira, Neide; Devaux, Frédéric; Barbosa, Sónia; Garcia, Mathilde; Lemoine, Sophie; Coulpier, Fanny; et al. "Transcriptional and post-transcriptional regulation of yeast lactate and acetate transporters by a RNA helicase". Paper presented in MICROBIOTEC’13, 2013. Aguiar, Cristina Almeida; Almeida, Maria Judite; Almeida, Maria Teresa; Gomes, Andreia; Paiva, Sandra. "BioCientistas de Palmo e Meio – Hands-on Science for Pre-schoolers at the Department of Biology of University of Minho.". Paper presented in HSCI 2013 - 10th International Conference on Hands-on Science. Košice, Slovakia, 2013. Paiva, Sandra; Dias, Alice; Carvalho, Ana; Cunha, Ana; Gonçalves, Arminda Manuela; Silva, Carlos; Coutinho, Elisabete; et al. ""Tertúlias FNACiência: the socialization of knowledge"". Paper presented in SciComPt 2013 - Conference on Science Communication, 2013. Vaz, Estelita; Dias, Alice; Carvalho, Ana; Cunha, Ana; Gonçalves, Arminda Manuela; Silva, Carlos; Coutinho, Elisabete; et al. ""Science Festival"". Paper presented in SciComPt 2013 - Conference on Science Communication, 2013. Pinheiro, Ana Isabel; Carvalho, Ana; Paiva, Sandra; Vaz, Estelita. ""Science communication in a local journal: ECUM and Correio do Minho"". Paper presented in SciComPt 2013 - Conference on Science Communication, 2013. Aguiar, Cristina Almeida; Almeida, Maria Judite; Almeida, Maria Teresa; Gomes, Andreia; Paiva, Sandra. "Biocientistas de palmo e meio at the Biology Department of the University of Minho". Paper presented in SciComPt 2013 - Congresso de Comunicação de Ciência, 2013. Silva, E.; Casal, M.; Paiva, S.; Queirós, O.. "Intracellular Trafficking of MCT1-Tagged GFP.". Paper presented in EMBO Young Scientists Forum 2013, Lisbon, Portugal, 2013. Vieira, Neide; Mota, Sandra; Devaux, Frédéric; Barbosa, Sónia; Garcia, Mathilde; Lemoine, Sophie; Coulpier, Fanny; et al. "The RNA helicase Dhh1 as a regulator of monocarboxylic acids transporters expression in yeast". Paper presented in SMYTE30 (Small Meeting in Yeast Transport and Energetics), Salamanca, Spain, 2012. Becuwe, Michel; Vieira, Neide; Lara, David; Gomes-Rezende, Jéssica; Soares-Cunha, Carina; Casal, Margarida; Haguenauer-Tsapis, Rosine; et al. "A molecular switch on a yeast arrestin-like protein connects glucose signalling to ubiquitin-dependent transporter endocytosis". Paper presented in Gordon Research Conference on Lysosomes & Endocytosis, Andover, USA, 2012. Silva, E.; Casal, M.; Paiva, S.; Queirós, O.. "Subcellular Localizations of the Monocarboxylate Transporters MCT1 Tagged with Green Fluorescence Protein in Different Cancer Cell Lines". Paper presented in Metabolism 2012: From signaling to disease, Heidelberg, Germany, 2012. Pereira, Filipa; Johansson, Björn; Ribeiro, G; Casal, Margarida; Paiva, Sandra. "Screening for interactions with predicted soluble domains of the yeast lactate transporter JEN1". Paper presented in FEBS pratical course on Protein Interaction Modules. Split, Croatia, 2011. Becuwe, Michel; Vieira, Neide; Vincent, Olivier; Haguenauer-Tsapis, Rosine; Paiva, Sandra; Léon, Sébastien. "A metabolic switch on a yeast arrestin connects glucose signaling to transporter endocytosis.". Paper presented in EMBO meeting on Ubiquitin and ubiquitin-like modifiers. Cavtat, Croatia,, 2011. Vieira, Neide; Pereira, Filipa; Paiva, Sandra; Casal, Margarida; Brown, Alistair J.; Johansson, Björn; Brown, Alistair J. P.. "Plasmids for in vivo construction of integrative Candida albicans vectors in Saccharomyces cerevisiae". Paper presented in 25th International Conference on Yeast Genetics and Molecular biology, . Olsztyn, Poland, 2011. 10.1002/yea.1800 Bessa, Daniela; Paiva, Sandra; Moreira, Roxana; Casal, Margarida; Queirós, Odília. "Functional characterization of a Yarrowia lipolytica gene family coding for carboxylic acids permeases homologues". Paper presented in Small Meeting in Yeast Transport and Energetic SMYTE29, Brazil, 2011. Talaia, Gabriel; Diallinas, George; Casal, Margarida; Paiva, Sandra. "Pinpointing intracelllar trafficking determinants in the Jen1 yeast lactate transporter by domain swap.". Paper presented in MicroBiotec11 Congress. Braga, Portugal, 2011. Sá-Pessoa, Joana; Viegas, Sandra Cristina; Rocha, Gabriel; Diallinas, George; Paiva, Sandra; Arraiano, Cecília Maria; Casal, Margarida. "Discovery and initial characterization of members of the new YaaH family of microbial acetate transporters". Paper presented in MicroBiotec11 Congress. Braga, Portugal, 2011. Vieira, Neide; Johansson, Björn; MacCallum, Donna M.; Odds, Frank; Casal, Margarida; Brown, Alistair J.; Paiva, Sandra. "Functional specialization and differential regulation of short chain carboxylic acid transporters in the pathogen Candida albicans". Paper presented in Yeast Genetics and Molecular Biology Meeting (YGM). Manchester, UK, 2009. Strachotová, Dita; Paiva, Sandra; Casal, Margarida; Váchová, Libuše; Palková, Zdena. "Jen1p mediated lactate transport in yeast colony development". Paper presented in 26th Small Meeting on Yeast Transport and Energetics, SMYTE26, Braga, Portugal, 2008. Vieira, Neide; Casal, Margarida; Johansson, Björn; Brown, Alistair J.; Paiva, Sandra. "Assessing the role of CaJEN2 dicarboxylate permease in fungal virulence.". Paper presented in Yeast Genetics and Molecular Biology Meeting. Toronto, Canada, 2008. Paiva, Sandra; Urban-Grimal, Danièle; Haguenauer-Tsapis, Rosine; Casal, Margarida. "Glucose-regulated ubiquitylation of the Jen1 permease of Saccharomyces cerevisiae.". Paper presented in Yeast Genetics and Molecular Biology Meeting. Princeton University, USA, 2006. Paiva, S; Pereira, N; Barbosa, S; Casal, M. "Role of DHH1 gene in the regulation of monocarboxylic acid transporters expression in Saccharomyces cerevisiae.". Paper presented in MICRO’05& BIOTEC’05 Congress. Póvoa de Varzim, Portugal, 2005. Pereira, Leonor; Queirós, Odília; Paiva, Sandra; Moradas-Ferreira, Pedro; Casal, Margarida. "KLJEN1 and KLJEN2 are essencial for the transport of monocarboxylic and dicarboxylic acids in the yeast Kluyveromyces lactis.". Paper presented in MICRO’05& BIOTEC’05 Congress. Póvoa de Varzim, Portugal, 2005. Paiva, Sandra; Urban-Grimal, Danièle; Haguenauer-Tsapis, Rosine; Casal, Margarida. "Glucose-regulated ubiquitylation of the Jen1 permease of Saccharomyces cerevisiae.". Paper presented in MICRO’05& BIOTEC’05 Congress. Póvoa de Varzim, Portugal, 2005. Ramalho, Patrícia A.; Paiva, Sandra; Casal, Margarida; Ramalho, Maria Teresa; Cardoso, M. Helena; Cavaco-Paulo, Artur. "Reductive biological treatment of textile effluents". Paper presented in Simpósio Corantes e Pigmentos Orgânicos, 2004. Ramalho, Patrícia A.; Paiva, Sandra; Cavaco-Paulo, Artur; Ramalho, Maria Teresa; Cardoso, M. Helena. "A contribution for the identification of azo reductase activity in the intact yeast cells.". Paper presented in 11th International Congress on Yeasts (ICY 2004). Rio de Janeiro, Brasil, 2004. Paiva, Sandra; Devaux, Frédéric; Barbosa, Sónia; Jacq, Claude; Casal, Margarida. "Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae.". Paper presented in Yeast Genetics and Molecular Biology Meeting. University of Washington, Seattle, 2004. Barbosa, Sónia; Paiva, Sandra; Casal, Margarida. "The transcription of the monocarboxylic acid transporters JEN1 and ADY2 is downregulated by the gene DHH1 in Saccharomyces cerevisiae". Paper presented in Yeast Genetics and Molecular Biology Meeting. University of Washington, Seattle, USA, 2004. Ramalho, Patrícia A.; Paiva, Sandra; Barbosa, Sónia; Cavaco-Paulo, Artur; Casal, Margarida; Ramalho, Maria Teresa; Cardoso, M. Helena. "Is Saccharomyces cerevisiae azoreductase the plasma membrane ferric reductase?". Paper presented in The 7th International Conference on Plasma Membrane Redox Systems and their Role in Biological Stress and Disease. Asilomar, USA, 2004. Queirós, Odília; Paiva, Sandra; Moradas-Ferreira, Pedro; Casal, Margarida. "Molecular and physiological characterization of monocarboxylic acids permeases in the yeast Kluyveromyces lactis.". Paper presented in XXI International Conference on Yeast Genetics and Molecular Biology. Göteborg, Sweden, 2003. Paiva, Sandra; Soares-Silva, Isabel; Kötter, Peter; Entian, Karl-Dieter; Casal, Margarida. "The disruption of JEN1 from Candida albicans impairs the transport of lactate.". Paper presented in XXI International Conference on Yeast Genetics and Molecular Biology. Göteborg, Sweden, 2003. Paiva, Sandra; Soares-Silva, Isabel; Kötter, Peter; Entian, Karl-Dieter; Casal, Margarida. "The disruption of JEN1 from Candida albicans impairs the transport of lactate.". Paper presented in 13º Congresso Nacional de Bioquímica, Lisbon, Portugal, 2002. Queirós, Odília; Paiva, Sandra; Moradas-Ferreira, Pedro; Casal, Margarida. "Molecular and physiological characterization of mono- and dicarboxylic acids permeases in the yeast Kluyveromyces lactis.". Paper presented in 13º Congresso Nacional de Bioquímica, Lisbon, Portugal, 2002. Paiva, Sandra; Kruckeberg, Arthur L.; Casal, Margarida. "Catabolite inactivation of the lactate transporter in Saccharomyces cerevisiae: ubiquitination, endocytosis and degradation in the vacuole.". Paper presented in XX International Conference on Yeast Genetics and Molecular Biology. Prague, Czech Republic, 2001. Paiva, Sandra; Casal, Margarida; Kruckeberg, Arthur L.; van Dam, Karel; Leão, Cecília. "Functional expression, quantitation and cellular localization of the Jen1 lactate transporter of Saccharomyces cerevisiae tagged with the green fluorescent protein.". Paper presented in Gordon Research Conference "Membrane Transport Proteins". Connecticut College, USA, 2000. Casal, Margarida; Paiva, Sandra; Andrade, Raquel P.; Leão, Cecília. "Genetic and functional analysis of the Saccharomyces cerevisiae gene JEN1 encoding the lactate permease.". Paper presented in XIX International Conference on Yeast Genetics and Molecular Biology. Rimini, Italy, 1999. Schuller, Dorit; Andrade, Raquel P.; Paiva, Sandra; Queirós, Odília; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "Cloning of the genes involved on the lactate, acetate and malate transport in the yeasts Saccharomyces cerevisiae and Kluyveromyces. sp.". Paper presented in MICRO´99, Luso, Portugal, 1999. Paiva, Sandra; Casal, Margarida; Leão, Cecília. "Transport of acetate in mutants of Saccharomyces cerevisiae defective in monocarboxylate permeases.". Paper presented in 19th International Specialized Symposium on Yeasts (ISSY). Braga, Portugal, 1998. Casal, Margarida; Paiva, Sandra; Leão, Cecília. "JEN1, a gene coding for a monocarboxylate transporter in Saccharomyces cerevisiae.". Paper presented in XI Congresso Nacional de Bioquímica, Tomar, Portugal, 1998. Paiva, Sandra; Casal, Margarida; Leão, Cecília. "Transport of acetate in mutants of Saccharomyces cerevisiae defective in monocarboxylate permeases.". Paper presented in XI Congresso Nacional de Bioquímica, Tomar, Portugal, 1998.
Edited book	Mendes, Adélio; Onofre, António; Tavares, Carlos; Serrão, Ester; Granja, Helena; Maia, Hernâni L. S.; Marcos, João Carlos; et al. conversas com Ciência - Tertúlias FNACiência. Braga, Portugal: Comissão de Interação com a Sociedade da Escola de Ciências da Universidade do Minho. 2012. Published • Editor
Journal article	Cláudia Barata-Antunes; Gabriel Talaia; George Broutzakis; David Ribas; Pieter De Beule; Margarida Casal; Christopher J. Stefan; George Diallinas; Sandra Paiva. "Interactions of cytosolic tails in the Jen1 carboxylate transporter are critical for trafficking and transport activity". Journal of Cell Science (2022): https://doi.org/10.1242/jcs.260059. 10.1242/jcs.260059 Carmen Becerra-Rodríguez; Géraldine Taghouti; Perrine Portier; Sylvie Dequin; Margarida Casal; Sandra Paiva; Virginie Galeote. "Yeast Plasma Membrane Fungal Oligopeptide Transporters Display Distinct Substrate Preferences despite Their High Sequence Identity". Journal of Fungi 7 11 (2021): 963-963. https://doi.org/10.3390/jof7110963. 10.3390/jof7110963 Barata-Antunes, Cláudia; Alves, Rosana; Talaia, Gabriel; Casal, Margarida; Gerós, Hernâni; Mans, Robert; Paiva, Sandra. "Endocytosis of nutrient transporters in fungi: The ART of connecting signaling and trafficking". Computational and Structural Biotechnology Journal 19 (2021): 1713-1737. http://dx.doi.org/10.1016/j.csbj.2021.03.013. 10.1016/j.csbj.2021.03.013 Paiva, Sandra. "Transcriptional responses of Candida glabrata biofilm cells to fluconazole are modulated by the carbon source". npj Biofilms and Microbiomes (2020): http://dx.doi.org/10.1038/s41522-020-0114-5. 10.1038/s41522-020-0114-5 Rosana Alves; Maria Sousa-Silva; Daniel Vieira; Pedro Soares; Yasmin Chebaro; Michael C. Lorenz; Margarida Casal; et al. "Carboxylic Acid Transporters in Candida Pathogenesis". mBio 11 3 (2020): https://doi.org/10.1128/mBio.00156-20. 10.1128/mBio.00156-20 Alves, Rosana; Barata-Antunes, Cláudia; CASAL, Margarida; Brown AJP; Van Dijck, Patrick; Paiva, Sandra 2617-F4E9-8A01. "Adapting to survive: how Candida overcomes host-imposed constraints during human colonization.". Plos Pathogens (2020): Accepted Alves, Rosana; Sousa-Silva, Maria; Vieira, Daniel; Soares, Pedro; Chebaro Y; Lorenz Michael; Casal, Margarida; Soares-Silva, Isabel; Paiva, Sandra 2617-F4E9-8A01. "Carboxylate transportes in Candida pathogenesis". mBio (2020): Open access • Accepted Gómez-Varela, Ana I.; Stamov, Dimitar R.; Miranda, Adelaide; Alves, Rosana; Barata-Antunes, Cláudia; Dambournet, Daphné; Drubin, David G.; Paiva, Sandra; De Beule, Pieter A. A.. "Simultaneous co-localized super-resolution fluorescence microscopy and atomic force microscopy: combined SIM and AFM platform for the life sciences". Scientific Reports 10 1 (2020): http://dx.doi.org/10.1038/s41598-020-57885-z. Open access • 10.1038/s41598-020-57885-z Ribas, David; Soares-Silva, Isabel; Vieira, Daniel; Sousa-Silva, Maria; Sa-Pessoa, Joana; Azevedo-Silva, Joao; Viegas, Sandra Cristina; et al. "The acetate uptake transporter family motif "NPAPLGL(M/S)" is essential for substrate uptake.". Fungal genetics and biology : FG & B 122 (2019): 1-10. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:30339831&KeyUID=MEDLINE:30339831. 10.1016/j.fgb.2018.10.001 Oliveira-Pacheco, João; Alves, Rosana; Costa-Barbosa, Augusto; Cerqueira-Rodrigues, Bruno; Pereira-Silva, Patricia; Paiva, Sandra; Silva, Sónia; et al. "The Role of Candida albicans Transcription Factor RLM1 in Response to Carbon Adaptation". Frontiers in Microbiology 9 (2018): http://dx.doi.org/10.3389/fmicb.2018.01127. Published • 10.3389/fmicb.2018.01127 Alves, Rosana; Mota, Sandra; Silva, Sónia; F. Rodrigues, Célia; P. Brown, Alistair J.; Henriques, Mariana; Casal, Margarida; Paiva, Sandra. "The carboxylic acid transporters Jen1 and Jen2 affect the architecture and fluconazole susceptibility of Candida albicans biofilm in the presence of lactate". Biofouling 33 10 (2017): 943-954. http://dx.doi.org/10.1080/08927014.2017.1392514. Published • 10.1080/08927014.2017.1392514 Talaia, Gabriel; Gournas, Christos; Saliba, Elie; Barata-Antunes, Cláudia; Casal, Margarida; André, Bruno; Diallinas, George; Paiva, Sandra. "The a-Arrestin Bul1p Mediates Lactate Transporter Endocytosis in Response to Alkalinization and Distinct Physiological Signals". Journal of Molecular Biology 429 23 (2017): 3678-3695. http://dx.doi.org/10.1016/j.jmb.2017.09.014. Published • 10.1016/j.jmb.2017.09.014 Ribas, David; Sá-Pessoa, Joana; Soares-Silva, Isabel; Paiva, Sandra; Nygård, Yvonne; Ruohonen, Laura; Penttilä, Merja; Casal, Margarida. "Yeast as a tool to express sugar acid transporters with biotechnological interest". FEMS Yeast Research 17 2 (2017): http://dx.doi.org/10.1093/femsyr/fox005. Published • 10.1093/femsyr/fox005 Soares-Silva, Isabel; Ribas, David; Foskolou, Iosifina P.; Barata, Beatriz; Bessa, Daniela; Paiva, Sandra; Queirós, Odília; Casal, Margarida. "TheDebaryomyces hanseniicarboxylate transporters Jen1 homologues are functional inSaccharomyces cerevisiae". FEMS Yeast Research (2015): fov094. http://dx.doi.org/10.1093/femsyr/fov094. Published • 10.1093/femsyr/fov094 Mota, Sandra; Alves, Rosana; Carneiro, Catarina; Silva, Sónia; Brown, Alistair J.; Istel, Fabian; Kuchler, Karl; et al. "Candida glabrata susceptibility to antifungals and phagocytosis is modulated by acetate". Frontiers in Microbiology 6 (2015): http://dx.doi.org/10.3389/fmicb.2015.00919. Published • 10.3389/fmicb.2015.00919 Mota, Sandra; Vieira, Neide; Barbosa, Sónia; Delaveau, Thierry; Torchet, Claire; Le Saux, Agnès; Garcia, Mathilde; et al. "Role of the DHH1 Gene in the Regulation of Monocarboxylic Acids Transporters Expression in Saccharomyces cerevisiae". PLoS ONE 9 11 (2014): e111589. http://dx.doi.org/10.1371/journal.pone.0111589. Published • 10.1371/journal.pone.0111589 Lopes, C.; Fonseca, P.; Matamá, T.; Gomes, A.; Louro, C.; Paiva, S.; Vaz, F.. "Protective Ag:TiO2 thin films for pressure sensors in orthopedic prosthesis: the importance of composition, structural and morphological features on the biological response of the coatings". Journal of Materials Science: Materials in Medicine 25 9 (2014): 2069-2081. http://dx.doi.org/10.1007/s10856-014-5251-z. Published • 10.1007/s10856-014-5251-z Paiva, S.; Strachotová, D.; Kucerová, H.; Hlavácek, O.; Mota, S.; Casal, M.; Palková, Z.; Váchová, L.. "The transport of carboxylic acids and important role of the Jen1p transporter during the development of yeast colonies". Biochemical Journal 454 3 (2013): 551-558. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883321628&partnerID=MN8TOARS. 10.1042/BJ20120312 Sá-Pessoa, J.; Paiva, S.; Ribas, D.; Silva, I.J.; Viegas, S.C.; Arraiano, C.M.; Casal, M.. "SATP (YaaH), a succinate-acetate transporter protein in Escherichia coli". Biochemical Journal 454 3 (2013): 585-589. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883383732&partnerID=MN8TOARS. 10.1042/BJ20130412 Teixeira, Sílvia; Sá, Rosália; Grangeia, Ana; Silva, Joaquina; Oliveira, Cristiano; Ferráz, Luís; Alves, Ângela; et al. "Immunohystochemical analysis of CFTR in normal and disrupted spermatogenesis". Systems Biology in Reproductive Medicine 59 1 (2012): 53-59. http://dx.doi.org/10.3109/19396368.2012.718851. Published • 10.3109/19396368.2012.718851 Pacheco, António; Talaia, Gabriel; Sá-Pessoa, Joana; Bessa, Daniela; Gonçalves, Maria José; Moreira, Roxana; Paiva, Sandra; Casal, Margarida; Queirós, Odília. "Lactic acid production in Saccharomyces cerevisiae is modulated by expression of the monocarboxylate transporters Jen1 and Ady2". FEMS Yeast Research 12 3 (2012): 375-381. http://dx.doi.org/10.1111/j.1567-1364.2012.00790.x. Published • 10.1111/j.1567-1364.2012.00790.x Becuwe, Michel; Vieira, Neide; Lara, David; Gomes-Rezende, Jéssica; Soares-Cunha, Carina; Casal, Margarida; Haguenauer-Tsapis, Rosine; et al. "A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis". The Journal of Cell Biology 196 2 (2012): 247-259. http://dx.doi.org/10.1083/jcb.201109113. Published • 10.1083/jcb.201109113 Vieira, Neide; Casal, Margarida; Johansson, Björn; MacCallum, Donna M.; Brown, Alistair J.P.; Paiva, Sandra. "Functional specialization and differential regulation of short-chain carboxylic acid transporters in the pathogenCandida albicans". Molecular Microbiology 75 6 (2010): 1337-1354. http://dx.doi.org/10.1111/j.1365-2958.2009.07003.x. Published • 10.1111/j.1365-2958.2009.07003.x Paiva, S.; Vieira, N.; Nondier, I.; Haguenauer-Tsapis, R.; Casal, M.; Urban-Grimal, D.. "Glucose-induced ubiquitylation and endocytosis of the yeast Jen1 transporter. Role of lysine 63-linked ubiquitin chains". Journal of Biological Chemistry 284 29 (2009): 19228-19236. http://www.scopus.com/inward/record.url?eid=2-s2.0-67749127761&partnerID=MN8TOARS. 10.1074/jbc.M109.008318 Casal, Margarida; Paiva, Sandra; Queirós, Odília; Soares-Silva, Isabel. "Transport of carboxylic acids in yeasts". FEMS Microbiology Reviews 32 6 (2008): 974-994. http://dx.doi.org/10.1111/j.1574-6976.2008.00128.x. Published • 10.1111/j.1574-6976.2008.00128.x Soares-Silva, Isabel; Paiva, Sandra; Diallinas, George; Casal, Margarida. "The conserved sequence NXX[S/T]HX[S/T]QDXXXT of the lactate/pyruvate:H+symporter subfamily defines the function of the substrate translocation pathway". Molecular Membrane Biology 24 5-6 (2007): 464-474. http://dx.doi.org/10.1080/09687680701342669. Published • 10.1080/09687680701342669 Queirós, Odília; Pereira, Leonor; Paiva, Sandra; Moradas-Ferreira, Pedro; Casal, Margarida. "Functional analysis of Kluyveromyces lactis carboxylic acids permeases: heterologous expression of KlJEN1 and KlJEN2 genes". Current Genetics 51 3 (2006): 161-169. http://dx.doi.org/10.1007/s00294-006-0107-9. Published • 10.1007/s00294-006-0107-9 Ramalho, P.A.; Paiva, S.; Cavaco-Paulo, A.; Casal, M.; Cardoso, M.H.; Ramalho, M.T.. "Azo reductase activity of intact Saccharomyces cerevisiae cells is dependent on the Fre1p component of plasma membrane ferric reductase". Applied and Environmental Microbiology 71 7 (2005): 3882-3888. http://www.scopus.com/inward/record.url?eid=2-s2.0-22144499228&partnerID=MN8TOARS. 10.1128/AEM.71.7.3882-3888.2005 Soares-Silva, Isabel; Paiva, Sandra; Kötter, Peter; Entian, Karl-Dieter; Casal, Margarida. "The disruption ofJEN1fromCandida albicansimpairs the transport of lactate". Molecular Membrane Biology 21 6 (2004): 403-411. http://dx.doi.org/10.1080/09687860400011373. Published • 10.1080/09687860400011373 Paiva, Sandra; Devaux, Frederic; Barbosa, Sonia; Jacq, Claude; Casal, Margarida. "Ady2p is essential for the acetate permease activity in the yeastSaccharomyces cerevisiae". Yeast 21 3 (2004): 201-210. http://dx.doi.org/10.1002/yea.1056. Published • 10.1002/yea.1056 Paiva, S; Soares-Silva, I; Kotter, P; Entian, KD; Casal, M. "The disruption of JEN1 from Candida albicans impairs the transport of lactate.". Yeast 20 (2003): S242-S242. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000184161800577&KeyUID=WOS:000184161800577. Queiros, O; Paiva, S; Moradas-Ferreira, P; Casal, M. "Molecular and physiological characterization of monocarboxylic acids permeases in the yeast Kluyveromyces lactis.". Yeast 20 (2003): S237-S237. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000184161800564&KeyUID=WOS:000184161800564. Paiva, S.; Kruckeberg, A.L.; Casal, M.. "Utilization of green fluorescent protein as a marker for studying the expression and turnover of the monocarboxylate permease Jen1p of Saccharomyces cerevisiae". Biochemical Journal 363 3 (2002): 737-744. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036566150&partnerID=MN8TOARS. 10.1042/0264-6021:3630737 Makuc, J.; Paiva, S.; Schauen, M.; Krämer, R.; André, B.; Casal, M.; Leo, C.; Boles, E.. "The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane". Yeast 18 12 (2001): 1131-1143. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034834876&partnerID=MN8TOARS. 10.1002/yea.763 Casal, Margarida; Paiva, Sandra; Andrade, Raquel P.; Gancedo, Carlos; Leão, Cecília; Casal, M.; Paiva, S.; et al. "The lactate-proton symport of Saccharomyces cerevisiae is encoded by JEN1". Journal of Bacteriology 181 8 (1999): 2620-2623. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000079706600040&KeyUID=WOS:000079706600040. Published Paiva, S.; Althoff, S.; Casal, M.; Leão, C.; Paiva, S; Althoff, S; Casal, M; Leao, C. "Transport of acetate in mutants of Saccharomyces cerevisiae defective in monocarboxylate permeases". FEMS Microbiology Letters 170 2 (1999): 301-306. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032960160&partnerID=MN8TOARS. 10.1016/S0378-1097(98)00522-9
Newsletter article	Leão, Cecília; Rodrigues, Fernando José dos Santos; Paiva, Sandra; Queirós, Odília; Schuller, Dorit; Cássio, Fernanda; Cardoso, M. Helena; Casal, Margarida; Côrte-Real, Manuela. "Remoção Zimológica da acidez volátil e fixa de mostos e vinhos: da fisiologia à manipulação genética de leveduras.", Boletim de Biotecnologia, 2000
Thesis / Dissertation	Paiva, Sandra. "Identification and characterization of plasma membrane monocarboxylate transporters in Saccharomyces cerevisiae and Candida albicans". PhD, Universidade do Minho, 2002. Paiva, Sandra. "Caracterização molecular de transportadores de ácidos monocarboxílicos em Saccharomyces cerevisiae". Master, Universidade do Minho, 1998. Paiva, Sandra. "Mutagenesis on the araE gene encoding for Arabinose-H+ Symport Protein of Escherichia coli". Degree, 1995.

Other

Other output

Interactions of cytosolic termini of the Jen1 monocarboxylate transporter are critical for trafficking, transport activity and endocytosis. 2021. Cláudia Barata-Antunes; Gabriel Talaia; George Broutzakis; David Ribas; Pieter De Beule; Margarida Casal; Christopher J. Stefan; George Diallinas; Sandra Paiva. https://doi.org/10.1101/2021.09.27.461913.
10.1101/2021.09.27.461913

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2019/09/12	Nico Van Uden Opening Plenary Lecture: Metabolic signals triggering the endocytosis of nutrient transporters.	Small Meeting on Yeast Transport & Energetics (SMYTE 37th) (Nove Hrady, Czech Republic)
2018/06/09	Alternative carbon sources modulate Candida glabrata biofilm development on medical devices	XXI Jornadas de Biologia de Leveduras "Professor Nicolau van Uden" (Braga, Portugal)
2018/06/09	The role of Candida albicans transcriptor factor RLM1 in response to carbon adaptation	XXI Jornadas de Biologia de Leveduras "Professor Nicolau van Uden" (Braga, Portugal)
2018/06/09	Functional characterization of Human Copper Transporters hCTR1 and hCTR2 in the yeast Saccharomyces cerevisiae	XXI Jornadas de Biologia de Leveduras "Professor Nicolau van Uden" (Braga, Portugal)
2018	Signals and mechanisms of endocytosis of eukaryotic lactate transportes	Small Meeting on Yeast Transport & Energetics (SMYTE 36th) (Martina Franca, Italy)
2017/06	The impact of carbon source in Candida albicans virulence: participation of RLM1 in host pathogen interaction.	XLI Portuguese Genetics Conference (Aveiro, Portugal)
2017/05	Transferable skills lecture 1: Bridges between research and industry	3rd IDPASC Students Workshop (Braga, Portugal)
2016/12	Lactic acid increases the susceptibility of Candida albicans to fluconazole	XIX National Congress of Biochemistry (Guimarães, Portugal)
2016/12	Outreach activities: from Academia to the Industry	Science Communication course International Iberian Nanotechnology Laboratory and the Department of Communication Sciences – University of Minho (Braga, Portugal)
2016/12	Outreach activities and the Public	Science Communication course International Iberian Nanotechnology Laboratory and the Department of Communication Sciences – University of Minho (Braga, Portugal)
2016/11/25	Regulatory mechanisms of lactate transporters by endocytic signalling: a biomedical perspective	In the scope of the Advanced course on “Mecanismos Moleculares de Doença”, of the Doctoral Program in Health Sciences Faculdade de Medicina, Universidade de Coimbra (Coimbra, Portugal)
2016/06/30	Endocytic trafficking and signaling of lactate transporters in yeast and mammalian cells	University of Leuven (Leuven, Belgium)
2015/07	Biofilm formation, antifungal drug susceptibility and phagocytosis in Candida glabrata are modulated by the carbon source.	SMYTE – 33rd Small Meeting on Yeast and Transport Energetics Departamento de Recursos Naturais, Ambiente e Território - ISA-ULisboa e Departamento de Biologia - Universidade do Minho (Lisboa, Portugal)
2015/07	The study of the intracellular trafficking of the yeast monocarboxylate transporter Jen1 from Saccharomyces cerevisiae.	SMYTE – 33rd Small Meeting on Yeast and Transport Energetics Departamento de Recursos Naturais, Ambiente e Território - ISA-ULisboa e Departamento de Biologia - Universidade do Minho (Lisboa, Portugal)
2015/05	"My school of Sciences" a project from the University of Minho involving 5000 high school students and a network of 19 Schools from the Minho region"	SciComPt 2015 - Conference on Science Communication Rede SciComPt (Lagos, Faro e Tavira, Portugal)
2015/05	Candida glabrata susceptibility to antifungals and phagocytosis is modulated by the carbon source	XXXIX Portuguese Genetics Conference (Braga, Portugal)
2014/10/03	The interplay between glucose signaling and endocytic trafficking of a yeast transporter	October Yeast Super group talk Department of Molecular and Cell Biology, University of California Berkeley, USA (Berkeley, United States)
2014/06/13	Regulation of a transporter endocytosis by glucose signalling	Cell Biology Special Seminar Professor Chris Burd, at the Department of Cell Biology, Yale University, USA (New Haven, Connecticut, United States)
2014/06	Endocytosis and intracellular trafficking of plasma membrane transporters	Erasmus International Program TransProt Advanced Course on New insights into structure, function and regulation of transport proteins Erasmus International Program TransProt
2014/06	Study of the intracellular trafficking of the Saccharomyces cerevisiae lactate transporter Jen1 using domain swap experiments	XX Jornadas de Biologia de Leveduras “Professor Nicolau Van Uden” (Lisboa, Portugal)
2013/09	Role of the DHH1 gene in the regulation of monocarboxylic acids transporters expression in Saccharomyces cerevisiae.	Small Meeting in Yeast Transport and Energetics (SMYTE) 31 Izmir Institute of Technology (Antalya, Turkey)
2012/07	The regulation of Jen1 lactate transporter by Glucose signaling.	SMYTE30 (Small Meeting in Yeast Transport and Energetics) Sociedade Espanhola de Microbiologia (Salamanca, Spain)
2012/07	Transport of lactic acid across plasma membrane: implications in health and biotechnology.	SMYTE30 (Small Meeting in Yeast Transport and Energetics) Sociedade Espanhola de Microbiologia (Salamanca, Spain)
2012/06	DHH1 gene affects the regulation of monocarboxylic acids transporters expression in yeast	XIX Jornadas de Biologia de Leveduras "Professor Nicolau Van Uden" (Lisboa, Portugal)
2011/08	A metabolic switch on a yeast arrestin connects glucose signaling to transporter endocytosis.	Cold Spring Harbor Laboratory meeting on Yeast Cell Biology Cold Spring Harbor Laboratory (Cold Spring Harbor, Nova Iorque , United States)
2011/07	Connecting glucose signalling to ubiquitin-dependent transporter endocytosis: Arrestin the culprit!	25th International Conference on yeast Genetics and Molecular Biology Instituto de Bioquímica e Biofísica PAS (Olsztyn, Poland)
2010/09	Insights into the glucose-mediated endocytosis of yeast Jen1 lactate transporter	28th Small Meeting on Yeast Transport and Energetics (SMYTE) Jawaharlal Nehru University (New Delhi, India)
2009/06	Functional specialization and differential regulation of short chain carboxylic acid transporters in the pathogen Candida albicans	XVII Jornadas de Biologia das Leveduras “Professor Nicolau Van Uden” (Braga, Portugal)
2007/09	Role of carboxylate permeases in the pathogenicity of Candida albicans	25th Small Meeting on Yeast Transport and Energetics (SMYTE) (Arraial d'Ajuda, Brazil)
2006/08	Glucose-regulated ubiquitylation of the Jen1 permease of Saccharomyces cerevisiae.	24th Small Meeting in Yeast Transport and Energetics (SMYTE 24) (Praga, Czech Republic)
2005/09	Role of the component Fre1p of the plasma membrane ferric reductase on the azo reductase activity of intact Saccharomyces cerevisiae cells.	23rd Small Meeting on Yeast Transport and Energetics (SMYTE 23) (New Delhi, India)
2004/09	Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae.	22nd Small Meeting on Yeast Transport and Energetics (SMYTE 22) (Açores, Portugal)
2004/06	Reductive biological treatment of textil effluents.	3th International Conference on Textil Biotechnology (Graz, Austria)
2004	Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae	12as Jornadas de Biologia de Leveduras "Professor Nicolau van Uden" (Aveiro, Portugal)
2004	The azoreductase of yeast cells: a new feature of an old enzyme	12as Jornadas de Biologia de Leveduras "Prof. Nicolau van Uden" (Aveiro, Portugal)
2004	The transcript of the monocarboxilic acid transporters JEN1 and ADY2 is downregulated by the gene DHH1 in Saccharomyces cerevisiae	12as Jornadas de Biologia de Leveduras "Prof. Nicolau van Uden" (Aveiro, Portugal)
2003/08	The disruption of JEN1 from Candida albicans impairs the transport of lactate	21st Small Meeting on Yeast Transport and Energetics (SMYTE 21) (Bonn, Germany)
2003	Identification and characterization of the lactate permease from Candida albicans	11as Jornadas de Biologia de Leveduras "Professor Nicolau Van Uden" (Faro, Portugal)
2001	The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane	9as Jornadas de Biologia de Leveduras "Professor Nicolau Van Uden" (Alcochete, Portugal)
2000/09	Genetic aspects of carbon catabolite regulation of JEN1, the lactate permease gene of Saccharomyces cerevisiae: studies on transcription and GFP tagging.	18th Small Meeting on Yeast Transport and Energetics (SMYTE 18) (Ouro Preto, Brazil)
2000	Utilization of GFP as a marker for studying the expression of JEN1 of Saccharomyces cerevisiae	8as Jornadas de Biologia de Leveduras "Professor Nicolau van Uden" (Madrid, Spain)
1998/08	A new approach for removing acidity during an alcoholic fermentation: cloning a monocarboxylic transporter gene of Saccharomyces cerevisiae.	19th ISSY (Braga, Portugal)
1998/08	Genetic characterization of monocarboxylic acids transporters of Saccharomyces cerevisiae.	16th Small Meeting on Yeast Transport and Energetics (SMYTE 16) (Bratislava, Slovakia)
1998	Genetic characterization of monocarboxylic acids transporters of Saccharomyces cerevisiae	. 6as Jornadas de Biologia de Leveduras "Professor Nicolau van Uden" (Santarém, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2023/01/01 - Current	The Role of Phosphatidic Acid in Apolipoprotein E4 Pathogenesis. Co-supervisor of Inês Paula Ribeiro	Biologia (PhD) Universidade do Minho, Portugal
2021/09/01 - Current	Metabolic Induced Regulation in Candida albicans pathogenesis: the role of carboxylic acids and carboxylate transporters. Supervisor of Alexandra do Carmo Gomes Gonçalves	Biologia Molecular e Ambiental (PhD) Universidade do Minho, Portugal
2017/10 - 2023/02/10	Regulation of plasma membrane nutrient transporters in yeast. Supervisor of Cláudia Manuela Pinto Barata Antunes	Biologia Molecular e Ambiental (PhD) Universidade do Minho, Portugal
2021/10/01 - 2022	Metabolism of carboxylic acids in Fungal Infections Supervisor of Vitor Sérgio Coutinho Fernandes	Genética Molecular (Master) Universidade do Minho, Portugal
2021/10/01 - 2022	The role of organic acids in the pathogenicity of Candida albicans Supervisor of Faezeh Ghasemi	Genética Molecular (Master) Universidade do Minho, Portugal
2018/07/01 - 2021/12/10	Diversity of oligopeptide transport in industrial yeasts. Co-supervisor of Carmen Becerra Rodriguez	Programa Doutoral YEASTDOC: Yeast Biotechnology Doctoral Training Programme (PhD) Escola de Ciências, Universidade do Minho, Portugal Institut National de Recherche pour l’Agriculture l’Alimentation et l’Environnement Centre Occitanie-Montpellier, France
2015 - 2020	Function and regulation of Candida glabrata and C. albicans carboxylic acid transporters and their role in biofilm formation, antifungal drug resistance and phagocytosis Supervisor of Rosana Maria Abreu Alves	Biologia Molecular e Ambiental (PhD) Universidade do Minho, Portugal
2016/10/01 - 2018/06	Analysis of human copper transporters in yeast Supervisor	Genética Molecular (Master) Universidade do Minho, Portugal
2016/10/01 - 2018/03/20	Impact of alternative carbon sources on Candida pathogenesis Supervisor	Bioquímica Aplicada (Master) Universidade do Minho, Portugal
2016 - 2018/01/11	Development of bio-based nanoemulsions to improve physical and chemical stability of omega-3 fatty acids Co-supervisor	Bioquímica Aplicada (Master) Universidade do Minho, Portugal
2013 - 2018	Characterization of carboxylate transporters: functional and structural studies for the improvement of cell factories Co-supervisor of David Manuel Nogueira Ribas	Biologia Molecular e Ambiental (PhD) Universidade do Minho, Portugal
2012 - 2018	Endocytic trafficking and ubiquitylation of plasma membrane transporters in yeast Supervisor of Gabriel Azevedo Carreira Talaia da Rocha	Biologia Molecular e Ambiental (PhD) Universidade do Minho, Portugal
2016 - 2017/12/13	Expression of Megalin in Central Nervous System Co-supervisor	Bioquímica Aplicada (Master) Universidade do Minho, Portugal
2015/10 - 2017/07	Functional Expression of prokaryotic transporters in yeast Co-supervisor	Bioquímica Aplicada (Master) Universidade do Minho, Portugal
2016 - 2017/06/19	Characterization of the relationship between the GPCR Smoothened and the RNA-binding protein SMAUG in Drosophila Co-supervisor	Genética Molecular (Master) Universidade do Minho, Portugal
2015/10 - 2017/03	Heterologous expression of the Human Copper Transporters hCTR1 and hCTR2 in yeast for endocytic trafficking analysis Supervisor	Genética Molecular (Master) Universidade do Minho, Portugal
2015 - 2016/12/22	Role and Regulation of katanin in C. elegans embryo Co-supervisor	Genética Molecular (Master) Universidade do Minho, Portugal
2013 - 2014/12/08	Regulation and intracellular trafficking of monocarboxylate transporters in yeast Supervisor	Genética Molecular (Master) Universidade do Minho, Portugal
2010/01 - 2014/04	Study of the mechanisms of transport and regulation of carboxylic acids in Candida albicans and Candida glabrata Supervisor of Sandra Marlene da Silva Mota	Biologia Molecular e Ambiental (PhD) Universidade do Minho, Portugal
2009/09 - 2013/12	Structural-functional studies of plasma membrane carboxylate transporters in yeast Co-supervisor of Joana Margarida Sá Pessoa da Graça Santos	Biologia Molecular e Ambiental (PhD) Universidade do Minho, Portugal
2008/10 - 2013/12	Engineering of core Pentose Metabolism in Saccharomyces cerevisiae for Bio-ethanol Production Supervisor of Filipa Alexandra Barroso Pereira	Biologia (PhD) Universidade do Minho, Portugal
2012 - 2013/05/10	Caracterização do proteoma mitocondrial do cancro de cabeça e pescoço: análise de um caso clínico Co-supervisor	Genética Molecular (Master) Universidade do Minho, Portugal
2012 - 2013/04/15	Intracellular Trafficking of Plasma Membrane Transporters in Mammalian Cells Supervisor	Genética Molecular (Master) Universidade do Minho, Portugal
2011/10 - 2012/12	Characterization of monocarboxylate membrane transporters in Saccharomyces cerevisiae Supervisor	Genética Molecular (Master) Universidade do Minho, Portugal
2009/10 - 2011/01	Regulation and characterization of carboxylic acid transporters in Saccharomyces cerevisiae and Candida glabrata Supervisor	Genética Molecular (Master) Universidade do Minho, Portugal
2009/10 - 2011/01	Physiological and Molecular studies of carboxylate transporter homologues in Yarrowia lipolytica	Genética Molecular (Master) Universidade do Minho, Portugal
2006/01 - 2010/04	The Transport of Carboxylic Acids in Yeasts: from physiology towards structural-functional characterization of permeases Supervisor of Neide Marina Vieira Pereira	Biologia (PhD) Universidade do Minho, Portugal
2008/09 - 2009/09	The effect of high temperature on sugar transport in grape cells Supervisor	Universidade do Minho, Portugal
2005 - 2005	Role of the DHH1 gene in the regulation of monocarboxylic acids transporters expression in Saccharomyces cerevisiae Supervisor	Universidade do Minho, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2011/11 - Current	Coordinator of "Tertúlias FNACiência " (2011/11) Other (Member of the Organising Committee)
2019/06/11 - 2019/06/12	“1st Workshop on Quantitative microscopy for studying membrane dynamics”. Chair: Sandra Paiva. https://uminho18.wixsite.com/1stworkshopqm (2019/06/11 - 2019/06/12) Workshop (President of the Organising Committee)	International Iberian Nanotechnology Laboratory, Portugal
2018/11/09 - 2018/11/10	“1º encontro de Ciência Maria Alves Paiva”. Joint organization between the Municipality of Chaves and the University of Minho. Chaves. Invited Speakers: Manuel Sobrinho Simões, Jorge Paiva, Alexandre Quintanilha, Carlos Fiolhais, Elvira Fortunato, José Manuel Mejome, Isabel Palmeirim e Alexandre Quintanilha. With the High Sponsorship of His Excellency the President of the Portuguese Republic. Chair: Sandra Paiva. https://uminho18.wixsite.com/encontrociencia (2018/11/09 - 2018/11/10) Meeting (President of the Organising Committee)	Universidade do Minho, Portugal
2018/07/02 - 2018/07/13	International Advanced course on “Protein Degradation and Trafficking in Health and Disease” (sponsored by the American Embassy & FCT) (2018/07/02 - 2018/07/13)	Universidade do Minho, Portugal
2018/07/10 - 2018/07/12	2nd Small Meeting on Endocytic Trafficking and Signaling. Chair: Sandra Paiva. https://uminho18.wixsite.com/smets2 (2018/07/10 - 2018/07/12)	International Iberian Nanotechnology Laboratory, Portugal
2017/05/31 - 2017/05/31	“I Simpósio em Bioquímica Aplicada”. Chair. https://simposiobqaplicada.wixsite.com/sbqa (2017/05/31 - 2017/05/31) Symposium (President of the Organising Committee)
2016/09 - 2016/09	Coordinator of "European Night of Researchers" (2016/09 - 2016/09) Other (Member of the Organising Committee)
2016/04/25 - 2016/05/06	International Advanced course on “Protein Degradation and Trafficking in Health and Disease” (sponsored by the American Embassy & FCT) (2016/04/25 - 2016/05/06)	Universidade do Minho, Portugal
2016/04/28 - 2016/05/03	1st Small Meeting on Endocytic Trafficking and Signaling. Chair: Sandra Paiva. https://uminho16.wixsite.com/smets1 (2016/04/28 - 2016/05/03) Meeting (President of the Organising Committee)	International Iberian Nanotechnology Laboratory, Portugal
2016/05 - 2016/05	Coordinator of "Science Festival" (2016/05 - 2016/05) Festival (Member of the Organising Committee)
2016/03 - 2016/03	Coordinator of "iSci-Interface Ciência" (2016/03 - 2016/03) Other (Member of the Organising Committee)
2015/09 - 2015/09	Coordinator of "European Night of Researchers" (2015/09 - 2015/09) Other (Member of the Organising Committee)
2015/05 - 2015/05	Coordinator of "Science Festival" (2015/05 - 2015/05) Festival (Member of the Organising Committee)
2015/03 - 2015/03	Coordinator of "iSci-Interface Ciência" (2015/03 - 2015/03) Other (Member of the Organising Committee)
2014/09 - 2014/09	Coordinator of "European Night of Researchers" (2014/09 - 2014/09) Other (Member of the Organising Committee)
2014/05 - 2014/05	Coordinator of "Science Festival" (2014/05 - 2014/05) Festival (Member of the Organising Committee)
2014/03 - 2014/03	Coordinator of "iSci-Interface Ciência" (2014/03 - 2014/03) Other (Member of the Organising Committee)
2014 - 2014	"Ocupação Científica de Jovens nas Férias ", (Ciência Viva initiative -School of Sciences coordinator) (2014 - 2014) Other (Member of the Organising Committee)
2013/09/27 - 2013/09/27	Coordinator of "European Night of Researchers" (2013/09/27 - 2013/09/27) Other (Member of the Organising Committee)
2013/09 - 2013/09	International Conference SMYTE 31 (2013/09 - 2013/09)
2013/05 - 2013/05	Coordinator of "Science Festival" (2013/05 - 2013/05) Festival (Member of the Organising Committee)
2013/04 - 2013/05	International Advanced course on “Protein Degradation and Trafficking in Health and Disease” (sponsored by the American Embassy & FCT) (2013/04 - 2013/05)	Universidade do Minho, Portugal
2013 - 2013	"Ocupação Científica de Jovens nas Férias ", (Ciência Viva initiative -School of Sciences coordinator) (2013 - 2013) Other (Member of the Organising Committee)
2012/11 - 2012/11	Coordinator of "iSci-Interface Ciência" (2012/11 - 2012/11) Other (Member of the Organising Committee)
2012/09/28 - 2012/09/28	Coordinator of "European Night of Researchers" (2012/09/28 - 2012/09/28) Other (Member of the Organising Committee)
2012/05 - 2012/05	Coordinator of "Science Festival" (2012/05 - 2012/05) Festival (Member of the Organising Committee)
2011/11 - 2011/11	Coordinator of "iSci-Interface Ciência" (2011/11 - 2011/11) Other (Member of the Organising Committee)
2011/05 - 2011/05	Coordinator of "Science Festival" (2011/05 - 2011/05) Festival (Member of the Organising Committee)
2010/07 - 2010/07	International Advanced course on "Plasma membrane transporters: physiology, genetics and phylogeny", (2010/07 - 2010/07)	Universidade do Minho, Portugal
2010/05/31 - 2010/06/02	National Congress “XXXV Jornadas Portuguesas de Genética” (2010/05/31 - 2010/06/02)	Universidade do Minho, Portugal
2010 - 2010	"Ocupação Científica de Jovens nas Férias ", (Ciência Viva initiative -School of Sciences coordinator) (2010 - 2010) Other (Member of the Organising Committee)
2009/06/19 - 2009/06/20	National Congress “XVII Jornadas de Biologia de Leveduras Professor Nicolau van Uden” (2009/06/19 - 2009/06/20)	Universidade do Minho, Portugal
2008/09/06 - 2008/09/09	International Congress: “26th Small Meeting on Yeast Transport and Energetics” (2009/09/06 - 2009/09/09)
2005/11/30 - 2005/12/03	National Congress MICRO’05-BIOTEC’05, (2005/11/30 - 2005/12/03)

Event participation

	Activity description Type of event	Event name Institution / Organization
2016/12 - 2016/12	Communicating Science: challenges, constraints, and opportunities Round table	Science Communication course International Iberian Nanotechnology Laboratory, Portugal Universidade do Minho, Portugal

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2020/03/11	"Studies to determine the structure and functionof Trk - K+ translocating system" (Thesis) Main arguer	Deepika Uttam Kale (PhD) Jihoceská Univerzita v Ceských Budejovicích, Czech Republic
2020/03/02	“Metabolic networks and metabolism in acute myeloid leukemia”. (Thesis) Main arguer	Olga Marisa da Silva Pereira (PhD) Universidade do Minho Escola de Medicina, Portugal
2019/09/27	“Unveiling the complex regulatory network governing antifungal drug resistance in Candida glabrata: from new regulators to new effectors”. (Thesis) Main arguer	Pedro Henrique Magalhães Fernandes Pais (PhD) Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/05/08	“mTOR pathway is a novel regulator of male fertility” (Thesis) Main arguer	Tito Miguel Boléo Teles de Jesus (PhD) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/09/22	“Functional and genetic analysis of sexual reproduction in the thermodimorphic fungal pathogen Paracoccidioides spp”. (Thesis) Main arguer	Jéssica Angélica Rezende Gomes (PhD) Universidade do Minho Escola de Medicina, Portugal
2016/06/30	“The identification of Ftr1 and Zrt1 as novel iron and zinc transceptors respectively in S. cerevisiae”. (Thesis) Main arguer	Joep Schothorst (PhD) Katholieke Universiteit Leuven Onderzoeksbeleid, Belgium

Interview (tv / radio show)

	Program	Topic
2015/09/25 - 2015/09/25	Portugal em Direto.	“Noite europeia dos Investigadores”. Entrevista a Sandra Paiva, Vice-Presidente da Escola de Ciências e coordenadora do evento na Universidade do Minho.
2012/03/28 - 2012/03/28	Mentes que brilham	Entrevista a Sandra Paiva sobre o artigo publicado no Journal of Cell Biology no programa Mentes que brilham.

Distinctions

Other distinction

2014	Fulbright Award under the Mutual Educational Exchange Program. Visiting Scholar at University of California, Berkeley
2011	2011 Nature Cell Biology Poster Prize Winners
2004	FEBS Youth Travel Grant to attend the FEBS advanced course “Cellular Signaling”, 21-24 of May, 2004, in Dubrovnik, Croatia.
2002	FEBS short-term fellowship, for a one month collaboration with the group of Professor Claude Jacq, at Ecole Normale Superieure, University of Paris, France.
2001	American Club Annual Award 2001
2000	FEBS Youth Travel Grant to attend the advanced course “New Dimensions in the Regulation of Gene Expression”. Spetses, Greece.
1999	FEBS short term fellowship, for a three months collaboration with the group of Professor Karel van Dam, at the University of Amsterdam, The Netherlands
1998	PhD fellowship from the European Union, Program PRAXIS XXI (PRAXIS XXI/BD/18198/98)
1995	ERASMUS semester fellowship from the European Union (Pic-94-p-1056), University of Leeds, England Erasmus, Netherlands