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Rita Mendes has a BSc in Biology from University of Lisbon, concluded in 2014, and a MSc in Molecular Genetics and Biomedicine, from Nova University of Lisbon, completed in 2016. She has published 10 papers in specialized journals. Currently, she is doing her PhD in Bioengineering at Nova University of Lisbon, in the field of Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology. Her expertise is mainly in the following areas: Drug Development; Big Data; Precision Medicine; Cancer; Nanomedicine; Machine Learning.
Identification

Personal identification

Full name
Ana Rita Soares Mendes

Citation names

  • Rita Mendes

Author identifiers

Ciência ID
261D-A56E-B957
ORCID iD
0000-0002-0672-2958

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Proficiency (C2) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2016
Concluded
 Mestrado em Genética Molecular e Biomedicina (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Combining Gene Therapy, Hyperthermia and Chemotherapy: an Opportunity to Revolutionize Cancer Treatment." (THESIS/DISSERTATION)
 18
2014
Concluded
 Licenciatura em Biologia - Ramo de Biologia Molecular e Genética (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"n/a" (THESIS/DISSERTATION)
 15
Projects

Grant

Designation Funders
2018/01/01 - 2021/12/31 A Precision medicine platform using patient-derived cancer cell models to predict drug efficacy
SFRH/BD/132163/2017
PhD Student Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing

Contract

Designation Funders
2017/01/02 - 2017/12/31 Carbon monoxide guided shuttles (COGSs) to fight Rheumatoid Arthritis
PTDC/QEQ-MED/1902/2014
Research Fellow
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference poster
  1. Mendes, Rita(261D-A56E-B957). "An ex vivo ovarian cancer platform to explore drug response at the individual patient level". Paper presented in Goodbye Flat Biology, 2019.
Journal article
  1. Abreu, Sofia; Silva, Fernanda; Mendes, Rita; Mendes, Teresa F.; Teixeira, Marta; Santo, Vítor E.; Boghaert, Erwin R.; Félix, Ana; Brito, Catarina. "Patient-derived ovarian cancer explants: preserved viability and histopathological features in long-term agitation-based cultures". Scientific Reports 10 1 (2020): http://dx.doi.org/10.1038/s41598-020-76291-z.
    Published • 10.1038/s41598-020-76291-z
  2. Fernandes, Alexandra R.; Mendonça-Martins, Inês; Santos, Marino F. A.; Raposo, Luís R.; Mendes, Rita(261D-A56E-B957); Marques, Joana; Romão, Carlos C.; et al. "Improving the Anti-inflammatory Response via Gold Nanoparticle Vectorization of CO-Releasing Molecules". ACS Biomaterials Science & Engineering 6 2 (2020): 1090-1101. http://dx.doi.org/10.1021/acsbiomaterials.9b01936.
    Open access • Published • 10.1021/acsbiomaterials.9b01936
  3. Roma-Rodrigues, Catarina; Mendes, Rita(261D-A56E-B957); Baptista, Pedro; Fernandes, Alexandra. "Targeting Tumor Microenvironment for Cancer Therapy". International Journal of Molecular Sciences 20 4 (2019): 840. http://dx.doi.org/10.3390/ijms20040840.
    Open access • Published • 10.3390/ijms20040840
  4. Pedro Pedrosa; Rita Mendes (261D-A56E-B957); Rita Cabral; Luísa M. D. R. S. Martins; Pedro V. Baptista; Alexandra R. Fernandes. "Combination of chemotherapy and Au-nanoparticle photothermy in the visible light to tackle doxorubicin resistance in cancer cells". Scientific Reports 8 1 (2018): https://doi.org/10.1038/s41598-018-29870-0.
    10.1038/s41598-018-29870-0
  5. Ribeiro, A.P.C.; Anbu, S.; Alegria, E.C.B.A.; Fernandes, A.R.; Baptista, P.V.; Mendes, Rita(261D-A56E-B957); Matias, A.S.; et al. "Evaluation of cell toxicity and DNA and protein binding of green synthesized silver nanoparticles". Biomedicine & Pharmacotherapy 101 (2018): 137-144. http://dx.doi.org/10.1016/j.biopha.2018.02.069.
    Published • 10.1016/j.biopha.2018.02.069
  6. Vinhas, Raquel; Rita Mendes; Fernandes, Alexandra R.; Baptista, Pedro V.. "Nanoparticles—Emerging Potential for Managing Leukemia and Lymphoma". Frontiers in Bioengineering and Biotechnology 5 79 (2017): http://dx.doi.org/10.3389/fbioe.2017.00079.
    Open access • Published • 10.3389/fbioe.2017.00079
  7. Rita Mendes; Pedro Pedrosa; João C. Lima; Alexandra R. Fernandes; Pedro V. Baptista. "Photothermal enhancement of chemotherapy in breast cancer by visible irradiation of Gold Nanoparticles". Scientific Reports (2017):
    10.1038/s41598-017-11491-8
  8. Mendes, Rita(261D-A56E-B957). "NANOPARTICLES AS EMERGING DIAGNOSTIC TOOLS IN LIQUID TUMOURS". EMJ Innovation 2 1 (2017): 80-87. https://www.emjreviews.com/innovations/article/nanoparticles-as-emerging-diagnostic-tools-in-liquid-tumours/.
    Open access • Published
  9. Mendes, Rita(261D-A56E-B957); Alexandra R. Fernandes; Pedro V. Baptista. "Gold Nanoparticle Approach to the Selective Delivery of Gene Silencing in Cancer—The Case for Combined Delivery?". Genes (2017): http://www.mdpi.com/2073-4425/8/3/94.
    10.3390/genes8030094
  10. Mendes, Rita(261D-A56E-B957); Bárbara Carreira; Alexandra R. Fernandes; Pedro V. Baptista. "Non-small cell lung cancer biomarkers and targeted therapy - two faces of the same coin fostered by nanotechnology". Expert Review of Precision Medicine and Drug Development 1 2 (2016): 155-168. http://dx.doi.org/10.1080/23808993.2016.1159914.
    10.1080/23808993.2016.1159914
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/05/03 PATIENT-DERIVED OVARIAN CANCER EXPLANTS: TOWARDS A PRECISION MEDICINE PLATFORM FOR DRUG DISCOVERY 26th Porto Cancer Meeting
(Portugal)