???global.info.a_carregar???
Pedro Miguel Santos completed the PhD in Biomedical Sciences at University of Porto, Portugal (2002). He was awarded with a post-doctoral grant at Institute of Bioengineering and Biosciences, IST (2002-2007). In 2008, he was hired as Invited Assistant Professor in the context of MIT-Portugal. He is an Assistant Professor at University of Minho and integrated member of the Center for Molecular and Environmental Biology (CBMA), since September 2008. He leads a research team focused on bacterial functional genomics, bacterial physiology and molecular biology, microbiomes and bioinformatics. Published 39 articles in journals (ORCID: 0000-0003-3234-4265). Has 1 book chapter. In his professional activities interacted with over 220 collaborators through co-authorship of scientific papers. Coordinated 3 research projects, as Principal investigator: BIOMYR: Towards the metabolic engineering of beta-myrcene pathway of Pseudomonas sp. M1: functional genomics and structural biochemistry approaches (PTDC/EBB-BIO/104980/2008); Wastewater reuse: improving the odds by understanding natural attenuation (ERANET, Inn-INDIGO/0004/2014); Towards the valorization of eucalyptus waste using Pseudomonas-based biocatalysts (PTDC/EAM-AMB/30488/2017). Participated in 13 research projects and was the local coordinator of National infrastructure network Genome PT(PINFRA/22184/2016). Currently, he is member of ARNET- Aquatic Research Network (LA/P/0069/2020). It is noteworthy, his contribution for: i) the elucidation of different bacterial molecular adaptation mechanisms to solvents and terpenes; ii) the description of unsual metabolic pathways such as those associated with metabolism of the monoterpene myrcene; iii) description of cetacean microflora and associated health statuses; iv) genomic heterogeneity among Pseudomonas aeruginosa clinical isolates; v) implementation of local infrastructures for genomics (MinION, Oxford Nanopore), proteomics (2-DE) and bioinformatics (server infrastructure and customized workflows for microbial genome and microbiome data analyses). Is Associated Editor in Evolutionary and Genomic Microbiology (Frontiers). He is member of the Directive Board of the Doctoral Program in Biology (since 2018) and of the Master Program in Molecular Genetics (since 2020). Supervised/co-Supervised 4 Post-doctoral fellows (BPD/GenomePT-CBMA/2018; BPD1/wrana/2017; SFRH/BPD/102006/2014; SFRH/BPD/86475/2012) and 5 PhD theses (SFRH/BD/113216/2015; SFRH/BD/98558/2013; SFRH/BD/76894/2011; SFRH/BD/80407/2011; SFRH/BD/38805/2007). Currently, is supervising 1 PhD thesis on bacterial enhanced performance through Adaptative Laboratory Evolution and co-supervising(PD/BD/146184/2019) 1 on the effect of mycorrizhization on soil microbiome (2023.04178.BDANA). Supervised over 15 MSc theses. Current scientific interests are: i) exploitation of the intricate ability of Pseudomonas spp. to tolerate, adapt and thrive in challenging environments (e.g. oligotrophic, polluted). Such competence holds great potential, as a source of novel biomolecules and cell factories, for different biotechnological applications, namely in the fields of biocatalysis, biosensors, and bioremediation; ii) characterization and exploitation of marine microbiome diversity and dynamics as biomonitoring and innovative biotech tools. In his curriculum Ciência Vitae the most frequent terms in the context of scientific and technological output are (among others): Evolution and adaptation; Biodiversity; Bioprospection; Pseudomonas; Microbiology; Bacterial pathogenesis and infection; Molecular Biotechnology; Multi-omics (transcriptomics; Genomics; proteomics; microbiome); Microbial communities; Marine ecosystem health; Biocontrol and Plant protection; Bioinformatics; Biorremediation; Biomarkers; Enzyme structure and function; beta-mircene metabolism; waste valorization.
Identification

Personal identification

Full name
Pedro Miguel Santos

Citation names

  • Santos, Pedro Miguel

Author identifiers

Ciência ID
2C16-CADA-2F72
ORCID iD
0000-0003-3234-4265

Addresses

  • Universidade do Minho, Departamento de Biologia, 4710-087, Braga, Braga, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Microbiology
  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
Affiliation

Science

Category
Host institution
Employer
2008/07 - 2008/09 Auxiliary Researcher (Research) Universidade de Lisboa, Portugal

Teaching in Higher Education

Category
Host institution
Employer
2009/09/01 - Current Assistant Professor (University Teacher) Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2008/09 - 2009/08 Invited Assistant Professor (University Teacher) Universidade do Minho, Portugal
2007/07 - 2008/07 Assistant Professor (University Teacher) Universidade de Lisboa, Portugal
Projects

Grant

Designation Funders
2016/04/01 - Current Effects of sewage outfalls on marine protected species
SFRH/BD/113216/2015
Supervisor
Fundação para a Ciência e a Tecnologia
Ongoing
2014/04/01 - 2018/03/31 Genomic contextualization of heterogeneity in Pseudomonas aeruginosa isolates
SFRH/BD/98558/2013
Supervisor
Fundação para a Ciência e a Tecnologia
Concluded
2014 - 2018 Exploitation of Burkholderia cepacia complex proteins to design new diagnostic and therapeutic strategies.
SFRH/BPD/102006/2014
Supervisor
Fundação para a Ciência e a Tecnologia
Concluded
2012/04/01 - 2015/12/31 Transcriptomic and proteomic responses to silver nanoparticles in aquatic microbes
SFRH/BD/80407/2011
Supervisor
Fundação para a Ciência e a Tecnologia
Concluded
2012/01/01 - 2015/12/31 PSEUDOCAT:OPTIMIZATION OF PSEUDOMONAS SP. M1 AS BIOCATALYST OF MYRCENE AND RELATED PLANT-DERIVED VOLATILES USING SYNTHETIC BIOLOGY
SFRH/BD/76894/2011
Supervisor
Fundação para a Ciência e a Tecnologia
Concluded
2013/04/01 - 2015/08/31 Mucoid phenotype switch in Burkholderia cepacia complex clinical isolates
SFRH/BPD/86475/2012
Supervisor
Fundação para a Ciência e a Tecnologia
Concluded
2007 - 2012 Global responses to phenol and myrcene in Pseudomonas at the level of cell membrane proteome unveiled by quantitative proteomics
SFRH/BD/38805/2007
Supervisor
Fundação para a Ciência e a Tecnologia
Concluded
2002/04/01 - 2007/07/31 Biodegradation of toxic compounds in Pseudomonas
SFRH/BPD/5693/2001
Post-doc Fellow
Fundação para a Ciência e a Tecnologia
Concluded
1998/06/01 - 2002/03/31 ROLE OF ALTERNATIVE SIGMA FACTORS IN GENERAL STRESS RESPONSE AND IN STYRENE CATABOLISM IN PSEUDOMONAS FLUORESCENS ST
PRAXIS XXI/BD/15899/98
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2017/06/01 - Current GenomePT - National Facility for Genome Sequencing and Analysis
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2021/01/01 - 2025/12/31 ARNET - Aquatic Research Network
Researcher
Universidade do Minho, Portugal

Universidade do Algarve, Portugal

Instituto Politécnico de Leiria, Portugal

Instituto Universitário de Ciências Psicológicas Sociais e da Vida, Portugal

Universidade Nova de Lisboa, Portugal

FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade de Lisboa Faculdade de Ciências, Portugal

Universidade de Coimbra, Portugal

Universidade de Évora, Portugal

Agência Regional para o Desenvolvimento da Investigação Tecnologia e Inovação, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal

Centro de Ciências do Mar e do Ambiente, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/06/01 - 2023/05/31 Development of sustainable date palm-based agrosystems by preserving their biodiversity
PRIMA/0001/2019
Researcher
Universidade do Minho, Portugal

Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal

Universidade do Minho Escola de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/01 - 2022/06/30 Development of advanced strategies and solutions for muscle tissue engineering based on electromechanical microenvironments
PTDC/BTM-MAT/28237/2017
Researcher
Universidade do Minho, Portugal

International Iberian Nanotechnology Laboratory, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/07/01 - 2022/06/30 Towards the valorization of eucalyptus waste using Pseudomonas-based biocatalysts
PTDC/EAM-AMB/30488/2017
Principal investigator
Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/07/25 - 2022/04/24 Influence of endosphere microbiome to control diseases in cork oak (Quercus suber L.)
PTDC/ASP-SIL/28635/2017
Researcher
Universidade do Minho, Portugal

Instituto Politécnico de Bragança, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 CENTRO DE BIOLOGIA MOLECULAR E AMBIENTAL
UID/BIA/04050/2019
Researcher
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2015/10/01 - 2018/09/30 Wastewater reuse: improving the odds by understanding natural attenuation
Inn-INDIGO/0004/2014
Principal investigator
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2013/07/01 - 2015/12/31 Cetaceans as marine ecosystem health sentinels
RECI/AAG-GLO/0470/2012
Researcher
Universidade de Aveiro, Portugal

Universidade de Aveiro Centro de Estudos do Ambiente e do Mar, Portugal

Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal

Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal

Universidade de Aveiro, Portugal

Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2013/04/01 - 2015/09/30 Exploitation of immunogenic proteins of the Burkholderia cepacia complex to design new diagnostic and therapeutic strategies.
PTDC/BBB-BIO/1958/2012
Researcher
Instituto de Biotecnologia e Bioengenharia, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2012/03/15 - 2015/09/14 NANOECOTOX-Impacts of metal nanoparticles to aquatic ecosystems: from community responses to cellular targets
PTDC/AAC-AMB/121650/2010
Researcher
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal

Universidade do Algarve, Portugal

Universidade do Minho Centro de Química, Portugal

Centro de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/04/04 - 2014/10/02 Benthic Estuarine Barcode(BEstBarcode): Development and application of massively paralelized sequencing for monitoring of estuarine macrobenthic communities
PTDC/MAR/113435/2009
Researcher
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal

Instituto do Mar, Portugal

Universidade do Porto Faculdade de Desporto, Portugal

University of Guelph Biodiversity Institute for Conservation Synthesis, Canada
Fundação para a Ciência e a Tecnologia
Concluded
2011/04/01 - 2014/09/30 ROOT-INT- Role of a two-component regulatory system in the early interaction between Sinorhizobium meliloti and plant root hairs
PTDC/BIA-MIC/113733/2009
Researcher
Universidade de Lisboa Instituto Superior Técnico, Portugal

Instituto de Biotecnologia e Bioengenharia, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Instituto Gulbenkian de Ciência, Portugal

Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia

Universidade do Algarve Faculdade de Ciências e Tecnologia
Concluded
2010/06/01 - 2014/05/31 Research in new biomass-based composites from renewable resources with improved properties for vehicle parts moulding
info:eu-repo/grantAgreement/EC/FP7/246176/EU
Researcher
Universidade do Algarve Faculdade de Ciências e Tecnologia
Concluded
2011/01/01 - 2013/12/31 Strategic Project - UI 4050 - 2011-2012
PEst-C/BIA/UI4050/2011
Researcher
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/04/01 - 2013/09/30 BIOMYR: Towards the metabolic engineering of beta-myrcene pathway of Pseudomonas sp. M1: functional genomics and structural biochemistry approaches
PTDC/EBB-BIO/104980/2008
Principal investigator
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal

Instituto de Biotecnologia e Bioengenharia, Portugal

Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia

Universidade do Algarve Faculdade de Ciências e Tecnologia
Concluded
2007/10/27 - 2010/10/26 Acute versus persistent infection by Burkholderia cepacia complex bacteria in cystic fibrosis patients: underlying mechanisms, in particular the role of exopolysaccharide biosynthesis
PTDC/SAU-MII/69591/2006
Researcher
Universidade de Lisboa Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia

Universidade do Algarve Faculdade de Ciências e Tecnologia
Concluded
2003/10/01 - 2006 Antimalarial drug resistance: from Yeast to Plasmodium
Researcher
Universidade do Algarve Faculdade de Ciências e Tecnologia
Concluded
2003/02/01 - 2006 Adaptation and resistance to organic acid food preservatives in yeast
Researcher
Universidade do Algarve Faculdade de Ciências e Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Mesquita, C.S.; Soares-Castro, Pedro; Santos, Pedro Miguel. "Pseudomonas aeruginosa: phenotypic flexibility and antimicrobial resistance". In Microbial pathogens and strategies for combating them: science, technology and education, edited by A. Méndez-Vilas, 650-665. Formatex Research Center, 2013.
    Published
Conference abstract
  1. Soares-Castro, Pedro; Araújo-Rodrigues, Helena; Godoy-Vitorino, Filipa; Ferreira, Marisa; Covelo, Pablo; López, Alfredo; Vingada, José; Eira, Catarina; Santos, Pedro Miguel. "Health status-associated microbiota fingerprints within the oral cavity of cetaceans". Paper presented in XX Iberian Symposium on Marine Biology Studies (SIEBM XX), Braga, 2019.
    Published • doi: 10.3389/conf.fmars.2019.08.00056
  2. Godoy-Vitorino, Filipa; Rodriguez-Hilario, Arnald; Araújo-Rodrigues, Helena; Mesquita, Cristina; Ferreira, Marisa; Vingada, José; Eira, Catarina; Santos, Pedro Miguel. "The microbiome of cetaceans as a health status indicator". Paper presented in Campus do Mar International Science Conference 2016, Vila Real, 2016.
    Published
Conference paper
  1. TEIXEIRA, MC; SANTOS, PM; FERNANDES, AR; et al.. "Yeast responses to stress induced by the herbicide 2,4-D: role of Pdr1p/Pdr3p-and Msn2p/Msn4p-regulated genes.". 2003.
  2. FERNANDES, AR; DURAO, PJ; SANTOS, PM; et al.. "Activation and significance of vacuolar H+-ATPase during yeast adaptation to stressful concentrations of the herbicide 2,4-D.". 2003.
Conference poster
  1. Rodrigues, A.M.; Roma-Rodrigues, Catarina; Santos, Pedro Miguel; Isabel Sá-Correia; Figueiredo, A.C.; Pedro, L.G.; Barroso, J.G.. "ß-Myrcene biotransformation by Pseudomonas sp. M1". Paper presented in 43rd International Simposium of Essential Oils, 2012.
Journal article
  1. Pedro Soares-Castro; Filipa Soares; Francisca Reis; Teresa Lino-Neto; Pedro M. Santos. "Bioprospection of the bacterial ß-myrcene-biotransforming trait in the rhizosphere". Applied Microbiology and Biotechnology (2023): https://doi.org/10.1007/s00253-023-12650-w.
    10.1007/s00253-023-12650-w
  2. Mesquita, Cristina S.; Ribeiro, Artur; Gomes, Andreia C.; Santos, Pedro M.. "Absence of Light Exposure Increases Pathogenicity of Pseudomonas aeruginosa Pneumonia-Associated Clinical Isolates". Biology 10 9 (2021): 837. http://dx.doi.org/10.3390/biology10090837.
    Open access • Published • 10.3390/biology10090837
  3. Daniela Costa; Telma Fernandes; Fátima Martins; José A. Pereira; Rui M. Tavares; Pedro M. Santos; Paula Baptista; Teresa Lino-Neto. "Illuminating Olea europaea L. endophyte fungal community". Microbiological Research 245 (2021): 126693-126693. https://doi.org/10.1016/j.micres.2020.126693.
    10.1016/j.micres.2020.126693
  4. Soares-Castro, Pedro; Soares, Filipa; Santos, Pedro M.. "Current Advances in the Bacterial Toolbox for the Biotechnological Production of Monoterpene-Based Aroma Compounds". Molecules 26 1 (2020): 91. http://dx.doi.org/10.3390/molecules26010091.
    10.3390/molecules26010091
  5. Viggor, Signe; Jõesaar, Merike; Soares-Castro, Pedro; Ilmjärv, Tanel; Santos, Pedro M.; Kapley, Atya; Kivisaar, Maia. "Microbial Metabolic Potential of Phenol Degradation in Wastewater Treatment Plant of Crude Oil Refinery: Analysis of Metagenomes and Characterization of Isolates". Microorganisms 8 5 (2020): 652. http://dx.doi.org/10.3390/microorganisms8050652.
    10.3390/microorganisms8050652
  6. Sílvia A. Sousa; Pedro Soares-Castro; António M.M. Seixas; Joana R. Feliciano; Bernardo Balugas; Celeste Barreto; Luísa Pereira; Pedro M. Santos; Jorge H. Leitão. "New insights into the immunoproteome of B. cenocepacia J2315 using serum samples from cystic fibrosis patients". New Biotechnology 54 (2020): 62-70. https://doi.org/10.1016/j.nbt.2019.08.006.
    10.1016/j.nbt.2019.08.006
  7. Pedro Soares-Castro; Helena Araújo-Rodrigues; Filipa Godoy-Vitorino; Marisa Ferreira; Pablo Covelo; Alfredo López; José Vingada; Catarina Eira; Pedro Miguel Santos. "Microbiota fingerprints within the oral cavity of cetaceans as indicators for population biomonitoring". Scientific Reports (2019): https://doi.org/10.1038/s41598-019-50139-7.
    10.1038/s41598-019-50139-7
  8. Pedro Soares-Castro; Trilok C. Yadav; Signe Viggor; Maia Kivisaar; Atya Kapley; Pedro M. Santos. "Seasonal bacterial community dynamics in a crude oil refinery wastewater treatment plant". Applied Microbiology and Biotechnology 103 21-22 (2019): 9131-9141. https://doi.org/10.1007/s00253-019-10130-8.
    10.1007/s00253-019-10130-8
  9. Cristina S. Mesquita; Pedro Soares-Castro; Alberta Faustino; Hugo M. Santos; José L. Capelo; Pedro Santos. "Identification of genomic loci associated with genotypic and phenotypic variation among Pseudomonas aeruginosa clinical isolates from pneumonia". Microbial Pathogenesis 136 (2019): 103702-103702. https://doi.org/10.1016/j.micpath.2019.103702.
    10.1016/j.micpath.2019.103702
  10. Barros, Diana; Pradhan, Arunava; Mendes, Vera M.; Manadas, Bruno; Santos, Pedro M.; Pascoal, Cláudia; Cássio, Fernanda. "Proteomics and antioxidant enzymes reveal different mechanisms of toxicity induced by ionic and nanoparticulate silver in bacteria". Environmental Science: Nano 6 4 (2019): 1207-1218. http://dx.doi.org/10.1039/c8en01067f.
    10.1039/c8en01067f
  11. Pedro Soares-Castro; Pedro Montenegro-Silva; Hermann J. Heipieper; Pedro M. Santos; Maia Kivisaar. "Functional Characterization of a 28-Kilobase Catabolic Island from Pseudomonas sp. Strain M1 Involved in Biotransformation of ß-Myrcene and Related Plant-Derived Volatiles". Applied and Environmental Microbiology 83 9 (2017): https://doi.org/10.1128/AEM.03112-16.
    10.1128/AEM.03112-16
  12. Godoy-Vitorino, Filipa; Rodriguez-Hilario, Arnold; Alves, Ana Luísa; Gonçalves, Filipa; Cabrera-Colon, Beatriz; Mesquita, Cristina Sousa; Soares-Castro, Pedro; et al. "The microbiome of a striped dolphin (Stenella coeruleoalba) stranded in Portugal". Research in Microbiology 168 1 (2017): 85-93. http://dx.doi.org/10.1016/j.resmic.2016.08.004.
    Published • 10.1016/j.resmic.2016.08.004
  13. Inês N. Silva; Pedro M. Santos; Mário R. Santos; James E. A. Zlosnik; David P. Speert; Sean W. Buskirk; Eric L. Bruger; et al. "Long-Term Evolution of Burkholderia multivorans during a Chronic Cystic Fibrosis Infection Reveals Shifting Forces of Selection". mSystems 1 3 (2016): https://doi.org/10.1128/mSystems.00029-16.
    10.1128/mSystems.00029-16
  14. Baptista P; Reis F; Pereira E; Tavares RM; Santos P; Richard F; Selosse MA; Lino-Neto T. "Soil DNA pyrosequencing and fruitbody surveys reveal contrasting diversity for various fungal ecological guilds in chestnut orchards.". (2015): http://europepmc.org/abstract/med/26391727.
    10.1111/1758-2229.12336
  15. Silva, Ines N; Santos, Pedro M; Moreira, Leonilde M. "Draft Genome Sequences of Two Burkholderia multivorans Sequential Isolates from a Chronic Lung Infection of a Cystic Fibrosis Patient.". Genome announcements 3 1 (2015): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:25676757&KeyUID=MEDLINE:25676757.
    10.1128/genomeA.01531-14
  16. Freschi, L.; Jeukens, J.; Kukavica-Ibrulj, I.; Boyle, B.; Dupont, M.-J.; Laroche, J.; Larose, S.; et al. "Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium". Frontiers in Microbiology 6 SEP (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84946833974&partnerID=MN8TOARS.
    10.3389/fmicb.2015.01036
  17. Soares-Castro, Pedro; Santos, Pedro M. "Deciphering the Genome Repertoire of Pseudomonas sp. M1 toward beta-Myrcene Biotransformation.". Genome biology and evolution 7 1 (2014): 1-17. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:25503374&KeyUID=MEDLINE:25503374.
    10.1093/gbe/evu254
  18. Madeira, Andreia; dos Santos, Sandra C.; Santos, Pedro M.; Coutinho, Carla P.; Tyrrell, Jean; McClean, Siobhan; Callaghan, Maire; Sa-Correia, Isabel. "Proteomic Profiling of Burkholderia cenocepacia Clonal Isolates with Different Virulence Potential Retrieved from a Cystic Fibrosis Patient during Chronic Lung Infection". Plos One 8 12 (2013): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000328734200062&KeyUID=WOS:000328734200062.
    10.1371/journal.pone.0083065
  19. Soares-Castro, Pedro; Santos, Pedro M.. "Towards the Description of the Genome Catalogue of Pseudomonas sp. Strain M1". Genome announcements 1 1 (2013): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:23405299&KeyUID=MEDLINE:23405299.
    10.1128/genomeA.00146-12
  20. Madeira, A.; Santos, P.M.; Coutinho, C.P.; Pinto-de-Oliveira, A.; Sá-Correia, I.. "Quantitative proteomics (2-D DIGE) reveals molecular strategies employed by Burkholderia cenocepacia to adapt to the airways of cystic fibrosis patients under antimicrobial therapy". Proteomics 11 7 (2011): 1313-1328. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953034713&partnerID=MN8TOARS.
    10.1002/pmic.201000457
  21. Soares-Castro, P.; Marques, D.; Demyanchuk, S.; Faustino, A.; Santos, P.M.. "draft genome sequences of two Pseudomonas aeruginosa clinical isolates with different antibiotic susceptibilities". Journal of Bacteriology 193 19 (2011): 5573-5573. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053578746&partnerID=MN8TOARS.
    10.1128/JB.05446-11
  22. Madeira, A.; Mira, N.P.; Santos, P.M.; Coutinho, C.P.; Pinto-De-Oliveira, A.; Moreira, A.S.; Roma-Rodrigues, C.; Sá-Correia, I.. "OMICS approaches to reveal Burkholderia cenocepacia adaptive strategies to long-term residence in the lungs of cystic fibrosis patients under antibiotic therapy". 1st Portuguese Meeting in Biomedical Engineering, ENBENG 2011 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-80053962948&partnerID=MN8TOARS.
    10.1109/ENBENG.2011.6026074
  23. Roma-Rodrigues, C.; Santos, P.M.; Benndorf, D.; Rapp, E.; Sá-Correia, I.. "Response of Pseudomonas putida KT2440 to phenol at the level of membrane proteome". Journal of Proteomics 73 8 (2010): 1461-1478. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953122046&partnerID=MN8TOARS.
    10.1016/j.jprot.2010.02.003
  24. Santos, P.M.; Simões, T.; Sá-Correia, I.. "Insights into yeast adaptive response to the agricultural fungicide mancozeb: A toxicoproteomics approach". Proteomics 9 3 (2009): 657-670. http://www.scopus.com/inward/record.url?eid=2-s2.0-60549092710&partnerID=MN8TOARS.
    10.1002/pmic.200800452
  25. Teixeira, M.C.; Santos, P.M.; Rodrigues, C.; Sá-Correia, I.. "Teaching expression proteomics: From the wet-lab to the laptop". Biochemistry and Molecular Biology Education 37 5 (2009): 279-286. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349855060&partnerID=MN8TOARS.
    10.1002/bmb.20315
  26. Santos, P.M.; Sá-Correia, I.. "Adaptation to ß-myrcene catabolism in Pseudomonas sp. M1: An expression proteomics analysis". Proteomics 9 22 (2009): 5101-5111. http://www.scopus.com/inward/record.url?eid=2-s2.0-70949106974&partnerID=MN8TOARS.
    10.1002/pmic.200900325
  27. Cosme, A.M.; Becker, A.; Santos, M.R.; Sharypova, L.A.; Santos, P.M.; Moreira, L.M.. "The outer membrane protein TolC from Sinorhizobium meliloti affects protein secretion, polysaccharide biosynthesis, antimicrobial resistance, and symbiosis". Molecular Plant-Microbe Interactions 21 7 (2008): 947-957. http://www.scopus.com/inward/record.url?eid=2-s2.0-47549111221&partnerID=MN8TOARS.
    10.1094/MPMI-21-7-0947
  28. Santos, P.M.; Roma, V.; Benndorf, D.; Von Bergen, M.; Harms, H.; Sá-Correia, I.. "Mechanistic insights into the global response to phenol in the phenol-biodegrading strain Pseudomonas sp. M1 revealed by quantitative proteomics". OMICS A Journal of Integrative Biology 11 3 (2007): 233-251. http://www.scopus.com/inward/record.url?eid=2-s2.0-34648827772&partnerID=MN8TOARS.
    10.1089/omi.2007.0009
  29. Santos, P.M.; Sá-Correia, I.. "Characterization of the unique organization and co-regulation of a gene cluster required for phenol and benzene catabolism in Pseudomonas sp. M1". Journal of Biotechnology 131 4 (2007): 371-378. http://www.scopus.com/inward/record.url?eid=2-s2.0-34648825385&partnerID=MN8TOARS.
    10.1016/j.jbiotec.2007.07.941
  30. Mendes, N.D.; Casimiro, A.C.; Santos, P.M.; Sá-Correia, I.; Oliveira, A.L.; Freitas, A.T.. "MUSA: A parameter free algorithm for the identification of biologically significant motifs". Bioinformatics 22 24 (2006): 2996-3002. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845359995&partnerID=MN8TOARS.
    10.1093/bioinformatics/btl537
  31. Teixeira, M.C.; Santos, P.M.; Fernandes, A.R.; Sá-Correia, I.. "A proteome analysis of the yeast response to the herbicide 2,4-dichlorophenoxyacetic acid". Proteomics 5 7 (2005): 1889-1901. http://www.scopus.com/inward/record.url?eid=2-s2.0-18844392542&partnerID=MN8TOARS.
    10.1002/pmic.200401085
  32. Santos, P.M.; Benndorf, D.; Sá-Correia, I.. "Insights into Pseudomonas putida KT2440 response to phenol-induced stress by quantitative proteomics". Proteomics 4 9 (2004): 2640-2652. http://www.scopus.com/inward/record.url?eid=2-s2.0-4444316792&partnerID=MN8TOARS.
    10.1002/pmic.200300793
  33. Fernandes, A.R.; Durão, P.J.; Santos, P.M.; Sá-Correia, I.. "Activation and significance of vacuolar H+-ATPase in Saccharomyces cerevisiae adaptation and resistance to the herbicide 2,4-dichlorophenoxyacetic acid". Biochemical and Biophysical Research Communications 312 4 (2003): 1317-1324. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344495239&partnerID=MN8TOARS.
    10.1016/j.bbrc.2003.11.072
  34. Kabelitz, N.; Santos, P.M.; Heipieper, H.J.. "Effect of aliphatic alcohols on growth and degree of saturation of membrane lipids in Acinetobacter calcoaceticus". FEMS Microbiology Letters 220 2 (2003): 223-227. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037470964&partnerID=MN8TOARS.
    10.1016/S0378-1097(03)00103-4
  35. Santos, P.M.; Mignogna, G.; Heipieper, H.J.; Zennaro, E.. "Occurrence and properties of glutathione S-transferases in phenol-degrading Pseudomonas strains". Research in Microbiology 153 2 (2002): 89-98. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036178355&partnerID=MN8TOARS.
    10.1016/S0923-2508(01)01293-1
  36. Santos, P.M.; Leoni, L.; Di Bartolo, I.; Zennaro, E.. "Integration host factor is essential for the optimal expression of the styABCD operon in Pseudomonas fluorescens ST". Research in Microbiology 153 8 (2002): 527-536. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036034159&partnerID=MN8TOARS.
    10.1016/S0923-2508(02)01358-X
  37. Santos, P.M.; Di Bartolo, I.; Blatny, J.M.; Zennaro, E.; Valla, S.; Santos, PM; Di Bartolo, I; et al. "New broad-host-range promoter probe vectors based on the plasmid RK2 replicon". FEMS Microbiology Letters 195 1 (2001): 91-96. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035808974&partnerID=MN8TOARS.
    10.1016/S0378-1097(00)00551-6
  38. Santos, P.M.; Blatny, J.M.; Di Bartolo, I.; Valla, S.; Zennaro, E.. "Physiological analysis of the expression of the styrene degradation gene cluster in Pseudomonas fluorescens ST". Applied and Environmental Microbiology 66 4 (2000): 1305-1310. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034033845&partnerID=MN8TOARS.
    10.1128/AEM.66.4.1305-1310.2000
  39. Isken, S; Santos, PMAC; deBont, JAM; Isken, S.; Santos, P.M.A.C.; De Bont, J.A.M.. "Effect of solvent adaptation on the antibiotic resistance in Pseudomonas putida S12". Applied Microbiology and Biotechnology 48 5 (1997): 642-647. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1997YK51400011&KeyUID=WOS:A1997YK51400011.
    10.1007/s002530051109
Thesis / Dissertation
  1. "Genomic contextualization of heterogeneity in Pseudomonas aeruginosa isolates". PhD, 2020. http://hdl.handle.net/1822/75987.
  2. Soares, Filipa Rafaela Lourenço. "Tuning of Pseudomonas sp. M1 towards ß-myrcene catabolism". Master, 2018. http://hdl.handle.net/1822/59486.
  3. Castro, Pedro Miguel Soares. "Optimization of Pseudomonas sp. M1 as a biocatalyst of ß-myrcene and related plantderived volatiles using Synthetic Biology". PhD, 2017. http://hdl.handle.net/1822/45767.
  4. Silva, Pedro José Pereira da. "Pathogenic potential characterization of two distinct "Pseudomonas aeruginosa strains"". Master, 2016. http://hdl.handle.net/1822/44395.
Activities

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2014 - 2020 Genomic contextualization of heterogeneity in Pseudomonas aeruginosa isolates
Supervisor
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2013 - 2019 Proteomic and physiological responses to metal nanoparticles in aquatic microbes
Co-supervisor
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2017 - 2018 Tuning of Pseudomonas sp. M1 towards ß-myrcene catabolism
Supervisor
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2017 - 2018 Regulation of the KtrAB Trasporter by c-di-AMP in B.subtilis
Co-supervisor
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2016 - 2017 Effects of radiation on the molecular dynamics of Pseudomonas aeruginosa
Supervisor
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2014 - 2015 Characterization of cetacean microbiomes as a health assessment landmark
Supervisor
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2011 - 2015 PSEUDOCAT:Optimization of Pseudomonas sp. M1 as biocatalyst of myrcene and related plant-derived volatiles using Synthetic Biology
Supervisor
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2013 - 2014 Functional characterization of the mobilome of Pseudomonas aeruginosa
Supervisor
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2012 - 2013 Strategies to characterize subpopulations of a distinct Pseudomonas aeruginosa clinical isolate
Supervisor
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2011 - 2012 The Microbiome of cetaceans as an health status marker
Supervisor
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2008 - 2012 Global responses to phenol and myrcene in Pseudomonas at the level of cell membrane proteome unveiled by quantitative proteomics
Co-supervisor
Universidade de Lisboa Instituto Superior Técnico, Portugal
2010 - 2011 Evaluation of myrcene catabolism and adaptation in Pseudomonas sp. M1 using massive parallel transcriptomics
Supervisor
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2023/10/19 - 2023/10/20 IV INTERNATIONAL MEETING OF THE PORTUGUESE SOCIETY OF GENETICS, Braga (2023)
Conference (Member of the Organising Committee)
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2022/09/29 - 2022/09/29 Workshop on Portable Sequencing at the European Researchers' Night
Festival
Eurpean Researchers' Night
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Association member

Society Organization name Role
2022 - Current Portuguese Society of Microbiology Member

Conference scientific committee

Conference name Conference host
2023 - Current GenomePT Symposium 2023 National Institute of Health Doutor Ricardo Jorge (Lisbon, Portugal)

Journal scientific committee

Journal title (ISSN) Publisher
2022/02/08 - Current Frontiers in Microbiology (1664-302X)