Identification
Personal identification
- Full name
- Laura Maria Alcântara
Citation names
- Alcântara, Laura
Author identifiers
- Ciência ID
- 2D1B-41ED-642B
- ORCID iD
- 0000-0002-3374-7405
Addresses
- UC-Biotech/Biocant - Parque Tecnológico de Cantanhede, núcleo 4, lote 8. , 3060-197, Cantanhede, Coimbra, Portugal (Professional)
Websites
- https://www.researchgate.net/profile/Laura_Alcantara (Professional)
- https://orcid.org/0000-0002-3374-7405 (Professional)
- https://www.cnc.uc.pt/en/people/l-alcantara (Professional)
Knowledge fields
- Natural sciences - Biological Sciences - Cell Biology
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
Portuguese (Mother tongue) | |||||
English | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) |
Education
Degree | Classification | |
---|---|---|
2013/03 - 2017/07
Concluded
|
Doutorado em Genética e Biologia Molecular (Doutoramento)
Universidade Estadual de Campinas, Brazil
"Discovery of new drug candidates for visceral leishmaniasis treatment: from image-based assay development to in vitro compounds
screening." (THESIS/DISSERTATION)
|
|
2007/08 - 2012/08
Concluded
|
Engenharia Biotecnológica (Bachelor)
Universidade Estadual Paulista "Júlio de Mesquita Filho" - UNESP, Brazil
" In vitro chemosensitization effects of tyrosine kinase and third generation P-glycoprotein inhibitors on multidrug resistant
malaria." (THESIS/DISSERTATION)
|
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2020/10 - Current | Postdoc (Research) | Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal | ||
2019/04 - 2020/09 | Postdoc (Research) | Instituto do Coração do Hospital das Clínicas da FMUSP - Incor, Brazil |
Instituto do Coração do Hospital das Clínicas da FMUSP - Incor, Brazil | ||
2017/11 - 2019/03 | Postdoc (Research) | Universidade de São Paulo, Brazil |
Universidade de São Paulo, Brazil |
Others
Category Host institution |
Employer | |
---|---|---|
2019/08 - 2019/11 | Visiting scientist | Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal | ||
2013/03 - 2017/07 | PhD fellow | Laboratório Nacional de Biociências, Brazil |
2016/11 - 2016/12 | Visiting scientist | Universiteit Antwerpen, Belgium |
Universiteit Antwerpen, Belgium | ||
2011/07 - 2012/06 | Research Trainee | Institut Pasteur Korea , South Korea |
Institut Pasteur Korea , South Korea | ||
2010 - 2011 | Research trainee | Universidade Estadual Paulista Júlio de Mesquita Filho - Câmpus de Assis, Brazil |
2009 - 2011 | Junior Enterprise Organization | Junior Enterprise Organization - Biotech Junior, Brazil |
Projects
Grant
Designation | Funders | |
---|---|---|
2022/01 - Current | Identification of host microRNAs regulating the infection of macrophages by invasive and non-invasive Salmonella strains.
EXPL/BIA-MIC/1251/2021
Co-Principal investigator
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2020/10 - Current | Large-scale identification and functional characterization of host microRNAs regulating infection by clinically relevant Staphylococcus
aureus strains
POCI-01-0145-FEDER-029999
Team Member
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2020/10 - 2022/10 | Functional high-throughput analysis of the role of microRNAs in regulating Staphylococcus aureus infection (miRs4Staph).
Marie Sklodowska-Curie fellowship 893942
Post-doc Fellow
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Concluded
|
2017/11 - 2019/03 | Development of secondary in vitro assays for Chagas disease and leishmaniasis early drug discovery.
VPPIS-003-PPE-15-2-6
Post-doc Fellow
Universidade de São Paulo, Brazil
|
Drugs for Neglected Diseases initiative
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2020/10 - 2022/10 | Functional high-throughput analysis of the role of microRNAs in regulating Staphylococcus aureus infection (miRs4Staph).
Marie Sklodowska-Curie fellowship 893942
Post-doc Fellow
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Ongoing
|
2019/04 - 2020/09 | New therapies for Chagas Disease: repurposing of drugs with synergistic effect with Benznidazole to counteract Trypanosoma
cruzi infection
CAPES/FCT - 28/2017
Post-doc Fellow
Instituto do Coração do Hospital das Clínicas da FMUSP - Incor, Brazil
|
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Fundação para a Ciência e a Tecnologia Concluded
|
2017 - 2018 | Identification of starting points for drug discovery and target identification against major neglected diseases
MMV2016
Post-doc Fellow
Universidade de São Paulo, Brazil
|
Medicines for Malaria Venture
Concluded
|
2014 - 2017 | NMTrypl - New Drugs for Trypanosomatidic Infections
603240
PhD Student Fellow
Centro Nacional de Pesquisa em Energia e Materiais, Brazil
|
European Commission Seventh Framework Programme for Research and Technological Development
Concluded
|
Outputs
Publications
Book chapter |
|
Conference abstract |
|
Conference poster |
|
Journal article |
|
Online resource |
|
Preprint |
|
Thesis / Dissertation |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2022/05/17 | Lecturer at a Specialization Program Course: Drug discovery for Chagas Disease: strategies based on drug combination and repurposing. |
Centro Universitário São Camilo (São Paulo, Brazil)
|
2021/05/26 | Lecturer at a Specialization Program Course: Drug discovery for Chagas Disease: strategies based on drug combination and repurposing. | Pós-Graduação em Prescrição Farmacêutica e Farmacologia Clínica
Centro Universitário São Camilo (São Paulo, Brazil)
|
2021/02/04 | Lecturer at PhD Program Course: Translational research and drug discovery for tropical neglected diseases: Strategies based on drug combination and repurposing. | PDBEB course: High-Throughput Screening for Target and Drug Discovery
CNC/CIBB - University of Coimbra (Cantanhede, Portugal)
|
2020/06/23 | Lecturer at a Specialization Program Course: Desenvolvimento de Novos Fármacos - Pesquisa Clínica - Da bancada à prateleira. | Pós-Graduação em Prescrição Farmacêutica e Farmacologia Clínica
Centro Universitário São Camilo (São Paulo, Brazil)
|
2019/12/04 | Translational research and drug discovery for tropical neglected diseases: Strategies based on drug combination and repurposing. | Weekly Seminars at FMUSP Heart Institute (InCor)
FMUSP Heart Institute (InCor) (São Paulo, Brazil)
|
2018/11/06 | Screening of the Pathogen Box library for discovery of broad-spectrum anti-trypanosomatidic agents. | XXXIV Annual Meeting of the Brazilian Society of Protozoology / XLV Annual Meeting on Basic Research in Chagas Disease
Brazilian Society of Protozoology (Caxambu, Minas Gerais, Brazil)
|
2015/07/20 | Speaker at a mini-course at Open Congress for Biology Students - Leishmania high content screenings | Open Congress for Biology Students
Universidade Estadual de Campinas/CAEB (Campinas, SP, Brazil)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2019 - Current | Effect of drug combinations on different stages of T. cruzi infection: study in strains belonging to different DTUs.
Co-supervisor of Marilda Savoia Nascimento
|
Tropical Medicine (PhD)
Instituto de Medicina Tropical - Faculdade de Medicina USP, Brazil
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2021/09/24 - 2021/09/24 | Volunteer of the 2021 edition of European Researchers´s Night - Coimbra (2021/09/24 - 2021/09/24)
Exhibition (Other)
|
Universidade de Coimbra, Portugal |
2018 - 2018 | Member of the organizing committee of this 2-days international event: Tools and Platforms for phenotypic Drug
Discovery (150 attendees) (2018 - 2018)
Conference (Member of the Organising Committee)
|
Universidade de São Paulo, Brazil Drugs for Neglected Diseases initiative, Switzerland |
2015 - 2015 | Member of the organizing committee of this 2-weeks event: Sao Paulo School of Advanced Science on Neglected
Diseases Drug Discovery – focus on Kinetoplastids (80 participants) (2015 - 2015)
Other (Member of the Organising Committee)
|
Centro Nacional de Pesquisa em Energia e Materiais, Brazil Fundação de Amparo à Pesquisa do Estado de São Paulo, Brazil |
2015 - 2015 | Member of the organizing committee of the meeting Building International Consortia on parasitic diseases: the NMTrypl experience
(100 participants) (2015 - 2015)
Meeting (Member of the Organising Committee)
|
Laboratório Nacional de Biociências, Brazil |
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2024/09/24 - 2024/09/24 | Participant investigator of the 2024 edition of European Researchers´ Night – Coimbra, Portugal. Activity: Super bugs: the
invisible threat!
Exhibition
|
European Researchers´ Night
Universidade de Coimbra, Portugal
|
2024/06/04 - 2024/06/07 | Attended the EpiViral conference "RNA biology in host-pathogen interactions" (Flask Talk and Poster presentation)
Conference
|
EpiViral conference - RNA biology in host-pathogen interactions
Universidade de Aveiro, Portugal
|
2023/09/29 - 2023/09/29 | Participant investigator of the 2023 edition of European Researchers´ Night – Coimbra, Portugal. Activity: Super bugs: the
invisible threat!
Exhibition
|
European Researchers´ Night
Universidade de Coimbra, Portugal
|
2023/01/26 - 2023/01/27 | Attended the RNA in disease - IX ptRNA meeting
Meeting
|
RNA in disease - IX ptRNA meeting
Universidade de Lisboa Instituto de Medicina Molecular, Portugal
|
2022/09/30 - 2022/09/30 | Participant investigator of the 2022 edition of European Researchers´ Night – Coimbra, Portugal. Activity: Super bugs: the
invisible threat!
Exhibition
|
European Researchers' Night
Universidade de Coimbra, Portugal
|
2022/08/22 - 2022/08/24 | Attended the XXXVII Annual Meeting of the Brazilian Society of Protozoology / XLVIII Annual Meeting on Basic Research in Chagas
Disease
Meeting
|
XXXVII Annual Meeting of the Brazilian Society of Protozoology / XLVIII Annual Meeting on Basic Research in Chagas Disease
SBPz - Brazilian Society of Protozoology, Brazil
|
2022/02/21 - 2022/02/25 | Attended (virtually) the Advanced Course : High-Throughput Screening for Target and Drug Discovery
Workshop
|
PDBEB course: High-Throughput Screening for Target and Drug Discovery
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
2021/10/27 - 2021/10/27 | Attended the webinar: From Base Pairs to Bedside: Antisense Modulation of RNA Splicing by Adrian Krainer.
Seminar
|
1st International ICBAS Webinar Series
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2021/10/13 - 2021/10/13 | Attended the webinar: Witnessing the fifty-year gene revolution: from single genes and their messenger RNAs to genomes and
their transcriptomes, by Nick Proudfoot
Seminar
|
1st International ICBAS Webinar Series
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2021/09/21 - 2021/09/24 | Attended (virtually) the Cold Spring Harbor Laboratory Conference: Microbiology Pathogenesis & Host Response
Conference
|
Microbial Pathegenesis & Host Response
Cold Spring Harbor Laboratory, United States
|
2021/04/27 - 2021/04/27 | Attended (virtually) the conference: Emerging Infectious Diseases and related environmental, clinical and translational challenges
Conference
|
Emerging Infectious Diseases and related environmental, clinical and translational challenges
Universidade de Coimbra, Portugal
|
2019/10/04 - 2019/10/04 | Attended the mini-course: How to Get Published by Elsevier
Other
|
How to Get Published
Universidade de Coimbra, Portugal
|
2018/11/05 - 2018/11/07 | Attended the international meeting: XXXIV Annual Meeting of the Brazilian Society of Protozoology / XLV Annual Meeting on
Basic Research in Chagas Disease
Meeting
|
XXXIV Annual Meeting of the Brazilian Society of Protozoology / XLV Annual Meeting on Basic Research in Chagas Disease
SBPz - Brazilian Society of Protozoology, Brazil
|
2018 - 2018 | Attended the III Hands On Course - From Genes To Drugs: An introduction to target-based drug discovery. (80h)
Other
|
From Genes To Drugs: An introduction to target-based drug discovery
Structural Genomics Consortium - UNICAMP, Brazil
|
2018 - 2018 | Attended the international symposium on drug discovery and development held by pharmaceutic companies and research institutes.
Symposium
|
Drug Discovery in Academia: learning from success and failure
Instituto Butantan, Brazil
|
2017/06/21 - 2017/06/23 | Attended the scientific Meeting: Searching for active compounds against neglected diseases
Meeting
|
III Scientific Meeting - Searching for active compounds against neglected diseases: from traditional knowledge to structural
synthesis
Universidade de São Paulo, Brazil
|
2016/06/06 - 2016/06/10 | Attended seminars on New Approaches to Drug Discovery against Tropical Diseases
Seminar
|
New approaches to drug discovery against tropical diseases
Universidade Estadual de Campinas, Brazil
|
2016 - 2016 | Attended the Course: Yeast-based high throughput approaches. (3h)
Workshop
|
New approaches to drug discovery against tropical diseases
Universidade Estadual de Campinas, Brazil
|
2016 - 2016 | Attended the Course: Primer in computer-aided drug design for tropical diseases (3h).
Workshop
|
New approaches to drug discovery against tropical diseases
Universidade Estadual de Campinas, Brazil
|
2015/11/09 - 2015/11/11 | Attended the XXXI Annual Meeting of the Brazilian Society of Protozoology / XLII Annual Meeting on Basic Research in Chagas
Disease
Meeting
|
XXXI Annual Meeting of the Brazilian Society of Protozoology / XLII Annual Meeting on Basic Research in Chagas Disease
SBPz - Brazilian Society of Protozoology, Brazil
|
2015/06/16 - 2015/06/23 | Attended seminars on Drug Discovery against Neglected Diseases
Seminar
|
Current Drug Discovery for Neglected Diseases
Centro Nacional de Pesquisa em Energia e Materiais, Brazil
|
2014 - 2014 | Hands-on Course: V Curso de Microscopia Eletrônica de Transmissão (120h)
Other
|
V Curso de Microscopia Eletrônica de Transmissão
Laboratório Nacional de Nanotecnologia, Brazil
|
2014 - 2014 | Hands-on Course: Data Analysis using the Software KNIME (8h)
Meeting
|
1º Encontro Brasileiro de High Content Screening.
Fundação Hemocentro de Ribeirão Preto, Brazil
|
2014 - 2014 | Hands-on Course: Automated Image Analysis Using the Software CellProfiler (8h)
Meeting
|
1º Encontro Brasileiro de High Content Screening
Fundação Hemocentro de Ribeirão Preto, Brazil
|
2014 - 2014 | Course: Basic Principles of High Content Screening (8h).
Meeting
|
1° Encontro Brasileiro de High Content Screening
Fundação Hemocentro de Ribeirão Preto, Brazil
|
2013 - 2013 | Worldleish 5 - Fifth World Congress on Leishmaniasis
Congress
|
Worldleish 5 - Fifth World Congress on Leishmaniasis |
2013 - 2013 | Workshop on Drug Discovery and Neglected Tropical Diseases
Workshop
|
Workshop on Drug Discovery and Neglected Tropical Diseases
Universidade Federal de São Carlos, Brazil
|
Association member
Society Organization name | Role | |
---|---|---|
2021/08/01 - Current | ESCMID - European society of clinical microbiology and infectious disease. | Member |
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2015/02 - 2015/06 | Professorship training program in Parasitology | Parasitology (Bachelor) | Universidade Estadual de Campinas, Brazil |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2013 - 2018 | Application of high content assays in early drug discovery for neglected diseases. | Several undergraduate students |
Distinctions
Other distinction
2022 | Postdoctoral fellowship
Universidade de Coimbra, Portugal
|
2020 | Postdoctoral fellowship
Universidade de Coimbra, Portugal
European Commission Marie Sklodowska-Curie Actions, Belgium |
2019 | Postdoctoral fellowship
Universidade de São Paulo, Brazil
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil |
2017 | Postdoctoral fellowship
Universidade de São Paulo, Brazil
Drugs for Neglected Diseases initiative, Switzerland |
2013 | PhD fellowship
Universidade Estadual de Campinas, Brazil
Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil |