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Identification

Personal identification

Full name
Carla Abreu

Citation names

  • Abreu, Carla M
  • Abreu, C

Author identifiers

Ciência ID
2F1C-A7D8-6E4A
ORCID iD
0000-0003-2026-9595

Email addresses

  • cpabreu@stemmatters.com (Professional)
  • carla.abreu03@gmail.com (Personal)

Addresses

  • Stemmatters, Parque de Ciência e Tecnologia Avepark, Zona Industrial da Gandra, 4805-017 , Barco, Guimarães, Portugal (Professional)

Knowledge fields

  • Engineering and Technology - Other Engineering and Technologies

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Spanish; Castilian Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2015/09 - 2020/12
Concluded
 Programa Doutoral em Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento)
Universidade do Minho, Portugal
"Strategies towards the recreation of a hair follicle regenerative microenvironment " (THESIS/DISSERTATION)
2008/09 - 2013/12
Concluded
 Mestrado Integrado em Ciências Farmacêuticas (Mestrado integrado)
Major in Sem especialização
Universidade do Porto Faculdade de Farmácia, Portugal
 15 valores
Affiliation

Science

Category
Host institution 		Employer
2021/10/01 - Current Researcher (Research) FairJourney Biologics SA, Portugal
2021/01/04 - 2021/10/31 Postdoc (Research) Universidade do Minho, Portugal
Research Institute on Biomaterials, Biodegradables and Biomimetics, Portugal
2014/05/27 - 2015/07/31 Researcher (Research) Universidade do Porto Faculdade de Medicina, Portugal
2011 - 2014 Research Trainee (Research) Universidade do Porto Faculdade de Farmácia, Portugal
2013/03/01 - 2013/05/31 Research Trainee (Research) Aix-Marseille Université, France
INSERM UMR 911, France

Others

Category
Host institution 		Employer
2022/07 - Current Senior Scientist Stemmatters Biotecnologia e Medicina Regenerativa SA, Portugal
2015/09/01 - 2020/12/10 PhD student Universidade do Minho, Portugal
Research Institute on Biomaterials, Biodegradables and Biomimetics, Portugal
Projects

Grant

Designation Funders
2018 - Current ECM_INK - Cells-self Extracellular Matrices-based Bioinks to create accurate 3D diseased skin tissue models
726061
PhD Student Fellow
Universidade do Minho, Portugal
 H2020 European Research Council
Ongoing
2015/12/01 - 2018/11/30 GENE2SKIN - Roadmap for advanced genetic engineering-based skin therapies
692221
PhD Student Fellow
Universidade do Minho, Portugal

King's College London, United Kingdom

Royal College of Surgeons in Ireland, Ireland
European Comission
Concluded
2016 - 2017 HAIRequivalent - Bioengineered hair follicles equivalents with controlled biological and architectural configuration
IF/00945/2014
PhD Student Fellow
Laboratório Associado ICVS 3B's, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2014/05/07 - 2015/07/31 Stromal stem cells therapy to prevent diabetes-induced changes in the central nervous system
EXPL/NEU-SCC/1193/2013
Research Fellow
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia, I. P.
Concluded
Outputs

Publications

Book chapter
  1. Carla M. Abreu. "Biofabrication Technologies in Hair Neoformation". 255-274. Springer International Publishing, 2022.
    10.1007/978-3-030-98331-4_12
Conference poster
  1. Abreu, Carla M. "Microguided laser ablation for the biofabrication of skin substitutes with follicular units". Paper presented in Final FoReCaST Conference, 2021.
  2. Abreu, Carla M; Reis, Rui L.; Marques, Alexandra P. "Study of the crosstalk between melanocytes and dermal papilla cells under hyperoxic and normoxic culture conditions". Paper presented in Term Stem, 2019.
  3. Lago, Manuela EL; Abreu, Carla M; Carvalho, Andreia F; da Silva, Lucília P; Cerqueira, Mariana T.; Pirraco, Rogério P; Reis, Rui L.; Marques, Alexandra P. "In vitro platform to study the crosstalk between the dermal white adipose tissue and dermal papilla cells.". Paper presented in Term Stem, 2019.
  4. Abreu, Carla M; Lago, Manuela EL; da Silva, Lucília P; Reis, Rui L.; Marques, Alexandra P. "Biofunctionalized gellan gum hydrogels for the recreation of the hair follicle mesenchymal compartment". Paper presented in 1st Discoveries Forum, 2019.
  5. Abreu, Carla M; Lago, Manuela EL; da Silva, Lucília D; Reis, Rui L.; Marques, Alexandra P. "Encapsulation of dermal papilla cells in functionalized-gellan gum hydrogels". Paper presented in FoReCaST Second Workshop, 2019.
  6. Abreu, Carla M; Cerqueira, Mariana T.; Pirraco, Rogério P; Reis, Rui L.; Watt, Fiona M; Marques, Alexandra P. "Epithelial stem-like cells for the recreation of the hair follicle epithelial compartment". Paper presented in Gene2Skin Summer School, 2018.
  7. Lago, Manuela EL; Abreu, Carla M; da Silva, Lucília P; Cerqueira, Mariana T.; Reis, Rui L.; Marques, Alexandra P. "Sulfate-modified gellan gum as a platform to recover the inductive potential of human dermal papilla cells.". Paper presented in Gene2Skin Summer School, 2018.
  8. da Silva, Lucília P; Lago, Manuela EL; Abreu, Carla M; Carvalho, Andreia F; Reis, Rui L.; Marques, Alexandra P. "Advances on the bioprinting a complex skin analogue substitute". Paper presented in European Wound Management Association Conference, 2018.
  9. Abreu, Carla M; Cerqueira, Mariana T.; Reis, Rui L.; Marques, Alexandra P. "Co-culturing epidermal stem-like cells with dermal papilla cells enhances both cell types proliferation". Paper presented in Gene2Skin Winter School, 2017.
  10. da Silva, Lucília P; Carvalho, Andreia F; Abreu, Carla M; Lago, Manuela EL; Reis, Rui L.; Marques, Alexandra P. "Cell-laden gellan gum-based bioinks for bioprinting a skin analogue". Paper presented in Gene2Skin Winter School, 2017.
  11. Abreu, Carla M; Lago, Manuela EL; da Silva, Lucília P; Cerqueira, Mariana T.; Reis, Rui L.; Marques, Alexandra P. "Tailoring gellan gum-based hydrogels for the recreation of the hair follicle epithelial compartment". Paper presented in Chem2Nature Second School, 2017.
  12. Lago, Manuela EL; Abreu, Carla M; da Silva, Lucília P; Moreira, Helena ; Cerqueira, Mariana T.; Pirraco, Rogério P; Reis, Rui L.; Marques, Alexandra P. "3D platform to evaluate the influence of intradermal adipose tissue on hair follicle cycle". Paper presented in Chem2Nature Second School, 2017.
  13. Abreu, Carla M; Lago, Manuela EL; da Silva, Lucília P; Moreira, Helena ; Reis, Rui L.; Marques, Alexandra P. "Gellan gum-based hydrogels for the recreation of hair follicle microenvironments". Paper presented in The Gene2Skin Conference, 2016.
  14. Oliveira, Sandra M; Abreu, Carla M; Morgado, C; Elliman, Stephen J; O'Brien, Timothy; Tavares, Isaura. "Efficacy of a novel mesenchymal stem cell population in a rat model of type 1 diabetes-induced neuropathic pain and cognitive impairment". Paper presented in 14th Meeting of the Mediterranean Group for the Study of Diabetes, 2015.
  15. Carvalho, C; Abreu, Carla M; Patinha, D; Afonso, J; Diniz, C; Manuela Morato. "The effect of diabetes in the distribution of adenosine receptors in the kidney of hypertensive rats.". Paper presented in 8th YES MEETING, 2013.
  16. Abreu, Carla M; Carvalho, C; Patinha, D; Manuela Morato; Albino-Teixeira, A. "Endogenous and exogenous adenosine and the distribution of adenosine receptors in the glomeruli of SHR diabetic rats". Paper presented in IJUP'2013 - 6th Meeting of Young Researchers of University of Porto, 2013.
Journal article
  1. Carla M. Abreu; Manuela E.L. Lago; Joana Pires; Rui L. Reis; Lucília P. da Silva; Alexandra P. Marques. "Gellan gum-based hydrogels support the recreation of the dermal papilla microenvironment". Biomaterials Advances 150 (2023): 213437-213437. http://dx.doi.org/10.1016/j.bioadv.2023.213437.
    10.1016/j.bioadv.2023.213437
  2. Carla M. Abreu; Rui L. Reis; Alexandra P. Marques. "Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions". Cell Proliferation (2021): https://doi.org/10.1111/cpr.13013.
    10.1111/cpr.13013
  3. Abreu, Carla M.; Marques, Alexandra P.. "Recreation of a hair follicle regenerative microenvironment: successes and pitfalls". Bioengineering & Translational Medicine (2021): http://dx.doi.org/10.1002/btm2.10235.
    10.1002/btm2.10235
  4. Abreu CM; Pirraco RP; Reis RL; Cerqueira MT; Marques AP. "Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment.". Stem cell research & therapy 12 1 (2021): 62. http://europepmc.org/abstract/med/33451331.
    Open access • Published • 10.1186/s13287-020-02104-9
  5. Carla M Abreu. "Rescuing Key Native Traits in Cultured Dermal Papilla Cells for Human Hair Regeneration". Journal of Advanced Research (2021): http://dx.doi.org/10.1016/j.jare.2020.10.006.
    Open access • In press • 10.1016/j.jare.2020.10.006
  6. Abreu, Carla M. "Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions". Cell Proliferation (2021):
    Accepted
  7. Carla M Abreu. "Adenosine A2A and A3 Receptors as Targets for the Treatment of Hypertensive-Diabetic Nephropathy". Biomedicines 8 11 (2020): 529-529. http://dx.doi.org/10.3390/biomedicines8110529.
    10.3390/biomedicines8110529
  8. Carla M Abreu. "Microscopy-guided laser ablation for the creation of complex skin models with folliculoid appendages". Bioengineering & Translational Medicine e10195 (2020): http://dx.doi.org/10.1002/btm2.10195.
    Open access • Published • 10.1002/btm2.10195
  9. Abreu, Carla. "Diabetes downregulates renal adenosine A2A receptors in an experimental model of hypertension". PLOS ONE 14 5 (2019): e0217552. http://dx.doi.org/10.1371/journal.pone.0217552.
    Open access • Published • 10.1371/journal.pone.0217552
  10. Ouaïssi M; Silvy F; Loncle C; Ferraz da Silva D; Martins Abreu C; Martinez E; Berthézene P; et al. "Further characterization of HDAC and SIRT gene expression patterns in pancreatic cancer and their relation to disease outcome.". PLOS One 9 10 (2014): | e108520. http://europepmc.org/abstract/med/25275504.
    Open access • Published • 10.1371/journal.pone.0108520
Thesis / Dissertation
  1. Abreu, Carla M. "Strategies towards the recreation of a hair follicle regenerative microenvironment.". PhD, Universidade do Minho, 2020.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/05 Micropatterning of a cultured skin substitute with folliculoid appendages European Wound Management Association Conference
European Wound Management Association (Paris, France)
2019/06 Complex bioprinted skin analogue 9th Conference of the European Wound Management Association
European Wound Management Association (Gothenburg, Sweden)
2019/05 Effect of EpSCs conditioned medium on dermal papilla cells TERMIS-EU
Tissue Engineering and Regenerative Medicine International Society (Rhodes, Greece)
2018/10 Effect of epidermal-stem like cells conditioned medium on dermal papilla cells Gene2Skin Final Conference
Universidade do Minho - 3Bs Research Group (Guimarães, Portugal)
2018/10 3D constructs as cell-based regenerative approaches and in vitro platforms to study the crosstalk between dermal white adipose tissue and dermal papilla cells Gene2Skin Final Conference
Universidade do Minho - 3Bs Research Group (Guimarães, Portugal)
2018/10 Skin-tailored bioinks Gene2Skin Final conference
Universidade do Minho - 3Bs Research Group (Guimarães, Portugal)
2018/09 Tailoring bioink biofeatures to meet skin microenvironments specificities 5th TERMIS World Congress
Tissue Engineering and Regenerative Medicine International Society (Kyoto, Japan)
2017/06 Biofunctionalized gellan gum hydrogels as tailored platforms for skin regenerative purposes TERMIS EU 2017
Tissue Engineering and Regenerative Medicine International Society (Davos, Switzerland)
2016/11 Gellan-gum based-hydrogels as a suitable platform to recreate the hair follicle 3D-compartments Chem2Nature First School
Universidade do Minho - 3Bs Research Group (Guimarães, Portugal)
2015/01 Efficacy of novel mesenchymal stem cell populations in a rat model of type 1 diabestes-induced neuropathic pain Portuguese Endocrinology Congress, 66th Annual Meeting of SPEDM
Portuguese Congress of Endocrinology (Funchal, Portugal)
2013/02 Distribution of adenosine receptors in the glomeruli of SHR diabetic rats XLIII Annual Meeting of the Portuguese Society of Pharmacology, XXXI Reunion of Clinical Pharmacology and XII Reunion of Toxicology
ICBAS - Universidade do Porto (Guimarães, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019/03/26 - 2019/03/26 3B's 20th Anniversary celebration (2019/03/26 - 2019/03/26)
Other (Co-organisor)
 Universidade do Minho - 3Bs Research Group, Portugal
2018/11/06 - 2018/11/12 3B's Research Group Pop Up Store Exhibition (2018/11/06 - 2018/11/12)
Exhibition (Co-organisor)
 Universidade do Minho - 3Bs Research Group, Portugal
2018/10/23 - 2018/10/24 Gene2Skin Final Conference (2018/10/23 - 2018/10/24)
Conference (Member of the Organising Committee)
 Universidade do Minho, Portugal
2018/06/16 - 2018/06/16 3Bs Family day - open day for staff's family (and other non-scientifc community) members. (2018/06/16 - 2018/06/16)
Other (Co-organisor)
 Universidade do Minho - 3Bs Research Group, Portugal
2018/06/06 - 2018/06/08 Gene2Skin Summer School - Biomaterials and molecular mechanisms in the context of skin regeneration (2018/06/06 - 2018/06/08)
Conference (Member of the Organising Committee)
 Universidade do Minho, Portugal
2017/11/13 - 2017/11/17 GENE2SKIN Winter School - Skin tissue disorders and advanced TE/genetic-based treatment strategies (2017/11/13 - 2017/11/17)
Conference (Member of the Organising Committee)
 Universidade do Minho, Portugal
2016/11/21 - 2016/11/25 Chem2Nature First School (2016/11/21 - 2016/11/25)
Conference (Member of the Organising Committee)
 Universidade do Minho, Portugal
2016/10/27 - 2016/10/28 Term Stem Conference (2016/10/27 - 2016/10/28)
Conference (Member of the Organising Committee)
 Universidade do Minho, Portugal
2016/10/24 - 2016/10/26 Gene2Skin Conference (2016/10/24 - 2016/10/26)
Conference (Member of the Organising Committee)
 Universidade do Minho, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2018/04/23 - 2018/04/24 Gene2Skin workshop -New tools for cutaneous wound healing and clinical progress
Workshop
King's College London, United Kingdom
2017/10/01 - 2017/10/03 Gene2Skin scientific retreat
Meeting
Universidade do Minho, Portugal

Association member

Society Organization name Role
2020 - Current Tissue Engineering and Regenerative Medicine International Society Society member
2016 - 2016 Federation of European Neuroscience Societies Society member
2016 - 2016 Portuguese Society for Neuroscience Society member
Distinctions

Award

2019 Scientific photography context - 2nd place
PhDynamics - I3B's, Portugal

Other distinction

2015 PhD scholarship (PD/BD/113800/2015)
Fundação para a Ciência e a Tecnologia, Portugal